schaftoside: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
schaftoside : A C-glycosyl compound that is apigenin substituted by beta-D-glucopyranosyl and an alpha-L-arabinopyranosyl moieties at positions 6 and 8 via C-glycosidic linkages. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
ID Source | ID |
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PubMed CID | 182689 |
MeSH ID | M0504289 |
Synonym |
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51938-32-0 |
schaftoside |
5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2r,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2s,3r,4s,5s)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one |
4h-1-benzopyran-4-one, 8alpha-l-arabinopyranosyl-6beta-d-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)- |
S9234 |
CCG-270071 |
Schaftoside (SS) is a bioactive compound of Herba Desmodii Styracifolii. The herb has traditionally been used to treat hepatitis and cholelithiasis.
Excerpt | Reference | Relevance |
---|---|---|
"The novel integrated double peak pharmacokinetic approach to studying the holistic pharmacokinetic properties of traditional Chinese medicine has been successfully developed and validated using AM as a model drug." | ( Integrated pharmacokinetics and biodistribution of multiple flavonoid C-glycosides components in rat after oral administration of Abrus mollis extract and correlations with bio-effects. Gu, N; Huo, M; Jiang, Z; Wang, H; Xiong, F; Yan, C; Zheng, C, 2015) | 0.42 |
" The method was applied to a pharmacokinetic study of Abrus cantoniensis Hance in rats." | ( Simultaneous determination of abrine, hypaphorine, schaftoside and soyasaponin Bb in rat plasma by UPLC-MS/MS and its application to a pharmacokinetic study after oral administration of Abrus cantoniensis Hance extract. Bu, Q; Huang, B; Li, C; Liu, C; Lu, P; Zhang, C, 2023) | 1.16 |
Excerpt | Reference | Relevance |
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") Merr has been established, based on analysis of high-performance liquid chromatography fingerprint combined with the similarity analysis (SA), hierarchical cluster analysis (HCA), principal component analysis (PCA), discriminant analysis (DA) and the quantitative analysis multi-components by single marker (QAMS) method." | ( Quantitative and Chemical Fingerprint Analysis of Desmodium styracifolium by High-Performance Liquid Chromatography Combined with Chemometrics. Chen, L; Cheng, X; Tang, X; Yang, Q, 2020) | 0.56 |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 8 (50.00) | 24.3611 |
2020's | 8 (50.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (32.59) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 18 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |