Page last updated: 2024-08-08 00:33:38
Mast/stem cell growth factor receptor Kit
A mast/stem cell growth factor receptor that is encoded in the genome of mouse. [OMA:MOUSE17014, PRO:DNx]
Synonyms
SCFR;
EC 2.7.10.1;
Proto-oncogene c-Kit;
Tyrosine-protein kinase Kit
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (4)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| imatinib | Mus musculus (house mouse) | GI50 | 0.3500 | 1 | 1 |
| su 11248 | Mus musculus (house mouse) | GI50 | 0.0030 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one | Mus musculus (house mouse) | EC50 | 0.0460 | 1 | 1 |
| gs-9973 | Mus musculus (house mouse) | EC50 | 0.4450 | 1 | 1 |