8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Sensitivity and Specificity in 9 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (77.78) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalipatnapu, S | 1 |
| Pucadyil, TJ | 1 |
| Harikumar, KG | 1 |
| Chattopadhyay, A | 1 |
| Lahmame, A | 1 |
| Armario, A | 1 |
| Wood, SA | 1 |
| Pegg, SN | 1 |
| Simmonds, RJ | 1 |
| Stevenson, D | 1 |
| Rees, SA | 1 |
| Austin, PM | 1 |
| Raap, DK | 1 |
| Garcia, F | 1 |
| Muma, NA | 1 |
| Wolf, WA | 1 |
| Battaglia, G | 1 |
| van de Kar, LD | 1 |
| Joyce, MP | 1 |
| Carden, SE | 1 |
| Hain, HS | 1 |
| Belknap, JK | 1 |
| Mogil, JS | 1 |
| Zuideveld, KP | 1 |
| Treijtel, N | 1 |
| Van der Graaf, PH | 1 |
| Danhof, M | 1 |
| Kelder, D | 1 |
| Ross, SB | 1 |
9 other studies available for 8-hydroxy-2-(di-n-propylamino)tetralin and Sensitivity and Specificity
| Article | Year |
|---|---|
Ligand binding characteristics of the human serotonin1A receptor heterologously expressed in CHO cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Binding Sites; Binding, Competitive | 2004 |
Differential responsiveness of inbred strains of rats to antidepressants in the forced swimming test: are Wistar Kyoto rats an animal model of subsensitivity to antidepressants?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Behavior, Animal; Desipramin | 1996 |
Development of chiral high performance liquid chromatographic assays for the enantiomers of 8-hydroxy-(di-n-propylamino)tetralin and three 8-keto-pyrrole-substituted analogues.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Chromatography, High Pressure Liquid; Liver; Rats; | 1996 |
Determination of U-89968E, a 5HT1a agonist in rat plasma using solid-phase extraction, precolumn derivatization and reversed-phase high-performance liquid chromatography.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Chromatography, High Pressure Liquid; Drug Stabilit | 1997 |
Sustained desensitization of hypothalamic 5-Hydroxytryptamine1A receptors after discontinuation of fluoxetine: inhibited neuroendocrine responses to 8-hydroxy-2-(Dipropylamino)Tetralin in the absence of changes in Gi/o/z proteins.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Brain; Drug Interactio | 1999 |
The effects of 8-OH-DPAT and (+/-)-pindolol on isolation-induced ultrasonic vocalizations in 3-, 10-, and 14-day-old rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Analysis of Variance; Animals; Animals, Newborn | 1999 |
Pharmacogenetic evidence for the involvement of 5-hydroxytryptamine (Serotonin)-1B receptors in the mediation of morphine antinociceptive sensitivity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Dose-Response Relationship, Drug; Drug | 1999 |
Enantioselective high-performance liquid chromatographic analysis of the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin. Application to a pharmacokinetic-pharmacodynamic study in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Chromatography, High Pressure Liq | 2000 |
Long lasting attenuation of 8-OH-DPAT-induced corticosterone secretion after a single injection of a 5-HT1A receptor agonist.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Corticosterone; Drug Interactions; Hydro | 1992 |