Streptomycin is an antibiotic that is used to treat a variety of bacterial infections. It was the first effective treatment for tuberculosis, a deadly disease that was once a leading cause of death worldwide. Streptomycin is a complex molecule that is produced by the bacterium *Streptomyces griseus*. The compound is a mixture of several closely related molecules, all of which have similar biological activity. Streptomycin works by binding to the 30S ribosomal subunit of bacteria, inhibiting protein synthesis. This disrupts the bacteria's ability to grow and reproduce, leading to their death. Streptomycin is typically given by injection, but it can also be administered orally. Streptomycin is an effective treatment for a variety of bacterial infections, including tuberculosis, plague, and tularemia. However, it is important to note that streptomycin can have several side effects, including hearing loss, dizziness, and kidney problems. Streptomycin is also effective against a wide range of bacteria, but resistance to the drug is a growing problem. This resistance can develop due to mutations in the bacterial ribosome. Streptomycin is an important antibiotic that has saved millions of lives. However, the development of resistance to the drug is a serious concern. Streptomycin is still used to treat some infections, particularly in developing countries. It is also used as a research tool to study the mechanisms of protein synthesis and bacterial resistance. Scientists are working on developing new antibiotics that are less likely to cause resistance. '
| ID Source | ID |
|---|---|
| PubMed CID | 19649 |
| CHEMBL ID | 372795 |
| CHEBI ID | 17076 |
| SCHEMBL ID | 3276 |
| MeSH ID | M0020595 |
| Synonym |
|---|
| n,n'''-[(1r,2r,3s,4r,5r,6s)-4-{5-deoxy-2-o-[2-deoxy-2-(methylamino)-alpha-l-glucopyranosyl]-3-c-formyl-alpha-l-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine |
| CHEBI:17076 , |
| 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-o-(2-deoxy-2-methylamino-alpha-l-glucopyranosyl)-3-c-formyl-beta-l-lyxopentanofuranoside |
| [2-deoxy-2-(dimethylamino)-alpha-l-glucopyranosyl]-(1->2)-[5-deoxy-3-c-formyl-alpha-l-lyxofuranosyl]-(1->4)-{n',n'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine} |
| streomycin |
| n,n'''-[(1r,2r,3s,4r,5r,6s)-4-({5-deoxy-2-o-[2-deoxy-2-(methylamino)-alpha-l-glucopyranosyl]-3-c-formyl-alpha-l-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine |
| nsc-14083 |
| o-2-deoxy-2-(methylamino)-.alpha.-l-glucopyranosyl-(1->2)-o-5-deoxy-3-c-formyl-.alpha.-l-lyxofuranosyl-(1->4)-n,n'-bis(aminoiminomethyl)-d-streptamine and liposome |
| d-streptamine, o-2-deoxy-2-(methylamino)-.alpha.-l-glucopyranosyl-(1->2)-o-5-deoxy-3-c-formyl-.alpha.-l-lyxofuranosyl-(1->4)-n,n'-bis(aminoiminomethyl)- |
| liposomal streptomycin |
| 1-[(1s,2r,3r,4s,5r,6r)-2-[(2r,3r,4r,5s)-3-[(2s,3s,4s,5r,6s)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydropyran-2-yl]oxy-4-formyl-4-hydroxy-5-methyl-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine |
| chemform |
| C00413 |
| STREPTOMYCIN , |
| 57-92-1 |
| SRY , |
| streptomycin a |
| DB01082 |
| streptomycin [inn:ban] |
| einecs 200-355-3 |
| estreptomicina [inn-spanish] |
| hsdb 1768 |
| neodiestreptopab |
| epa pesticide chemical code 006306 |
| streptomyzin [german] |
| d-streptamine, o-2-deoxy-2-(methylamino)-alpha-l-glucopyranosyl-(1-2)-o-5-deoxy-3-c-formyl-alpha-l-lyxofuranosyl-(1-4)-n,n'-bis(aminoiminomethyl)- |
| streptomicina [italian] |
| strepcen |
| brn 0074498 |
| gerox |
| agrept |
| caswell no. 804 |
| streptomycinum |
| streptomycine |
| hokko-mycin |
| agrimycin |
| ccris 5730 |
| 2-[(1r,2r,3s,4r,5r,6s)-3-(diaminomethylideneamino)-4-[(2r,3r,4r,5s)-3-[(2s,3s,4s,5r,6s)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine |
| streptomycin (inn) |
| streptomycin (tn) |
| D08531 |
| CHEMBL372795 |
| streptomyzin |
| streptomicina |
| AKOS015969759 |
| streptomycin, sulfate salt |
| y45qso73ob , |
| d-streptamine, o-2-deoxy-2-(methylamino)-alpha-l-glucopyranosyl-(1.fwdarw.2)-o-5-deoxy-3-c-formyl-alpha-l-lyxofuranosyl-(1.fwdarw.4)-n,n'-bis(aminoiminomethyl)- |
| unii-y45qso73ob |
| 4-18-00-07540 (beilstein handbook reference) |
| streptomycin sesquisulfate hydrate |
| streptomycin [hsdb] |
| streptomycin [inn] |
| streptomycin [mart.] |
| streptomycin [mi] |
| streptomycin [vandf] |
| streptomycin [who-dd] |
| streptomycin [green book] |
| AM84920 |
| EPITOPE ID:224553 |
| SCHEMBL3276 |
| UCSJYZPVAKXKNQ-HZYVHMACSA-N |
| AB00443813_02 |
| DTXSID4023597 |
| 1-[(1s,2r,3r,4s,5r,6r)-3-carbamimidamido-6-{[(2r,3r,4r,5s)-3-{[(2s,3s,4s,5r,6s)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2,4,5-trihydroxycyclohexyl]guanidine |
| bdbm50103513 |
| streptomycin sesquisulphate hydrate |
| AS-35042 |
| 1,-((1r,2r,3s,4r,5r,6s)-4-((2r,3r,4r,5s)- |
| streptomycin,(s) |
| -hydroxy-5-methyltetrahydrofuran-2-yloxy)- |
| 3-((2s,3s,4s,5r,6s)-4,5-dihydroxy-6 |
| -(hydroxymethyl)-3-(methylamino) |
| 2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine |
| tetrahydro-2h-pyran-2-yloxy)-4-formyl-4 |
| Q192717 |
| BRD-K07166362-330-02-8 |
| gtpl10923 |
| 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-o-(2-deoxy-2-methylamino-alpha-glucopyranosyl)-3-formylpentofuranoside |
| CS-0013964 |
| HY-B1906 |
| EN300-7481099 |
| n-[(1r,2r,3s,4r,5r,6s)-3-carbamimidamido-4-{[(2r,3r,4r,5s)-3-{[(2s,3s,4s,5r,6s)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2,5,6-trihydroxycyclohexyl]guanidine |
| a07aa04 |
| j01ga01 |
| estreptomicina (inn-spanish) |
| streptomycin (mart.) |
Streptomycin is an antibiotic that is used against a range of gram-positive and gram-negative bacteria. Its use has led to the development of antibiotic resistance in some pathogens.
Streptomycin has been available for over 60 years, yet optimal dosing in hemodialysis (HD) patients is not well defined. StrePTomycin resistance has been found to differ from ordinary one-step streptomycins resistance. Streptomycus sulfate has been known to be ototoxic since its use in the treatment of tuberculosis.
Streptomycin (SM) displays antimicrobial activity via inhibition of protein synthesis in bacteria. It is one of the major antituberculous drugs used in chemotherapy of tuberculosis (TB) Streptomycins can cause peripheral nerve damage when injected perineurally.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Streptomycin reduced the increase seen in GLUT4 protein following CLFS (CTL=89.4%±6.7%; STREP=41.0%±4.3%) and prevented increases in the mitochondrial proteins succinate dehydrogenase (SDH) and ATP synthase." | ( Streptomycin decreases the functional shift to a slow phenotype induced by electrical stimulation in engineered muscle. Baar, K; Khodabukus, A, 2015) | 2.58 |
| "Streptomycin (SM) displays antimicrobial activity via inhibition of protein synthesis in bacteria and it is one of the major antituberculous drugs used in chemotherapy of tuberculosis (TB). " | ( [Investigation of rpsL and rrs gene region mutations in streptomycin resistant Mycobacterium tuberculosis complex isolates]. Aslan, G; Emekdaş, G; Serin, MS; Tezcan, S; Ulger, M, 2009) | 2.04 |
| "Streptomycin did not inhibit A-site cleavage in rpsL mutants, which express streptomycin-resistant variants of ribosomal protein S12." | ( Ribosomal protein S12 and aminoglycoside antibiotics modulate A-site mRNA cleavage and transfer-messenger RNA activity in Escherichia coli. Hayes, CS; Holberger, LE, 2009) | 1.07 |
| "Streptomycin can cause peripheral nerve damage when injected perineurally. " | ( Effects of streptomycin on the rat infraorbital nerve. Dozić, S; Saulacić, N; Stajcić, Z, 2002) | 2.15 |
| "Streptomycin caused an increase in the endogenous respiration of S." | ( SELECTIVE INHIBITION OF PROLINE-INDUCED PIGMENTATION IN WASHED CELLS OF SERRATIA MARCESCENS. BLIZZARD, JL; PETERSON, GE, 1963) | 0.96 |
| "Streptomycin and kanamycin inhibit histamine release from mast cells challenged with IgE-directed secretagogue or compound 48/80, and the responsible mechanisms seem to implicate the Ca(2+)-antagonistic action on the stimulus-provoked influx of Ca2+ and impairment of the cellular events linked to exocytosis." | ( Influence of aminoglycoside antibiotics, streptomycin and kanamycin on histamine secretion in mast cells. Hazama, S; Kanno, M; Kikuchi, C, 1992) | 1.27 |
| "Streptomycin was used to increase the frequency of errors in protein synthesis in vivo. " | ( Streptomycin-induced, third-position misreading of the genetic code. Johnston, TC; Parker, J, 1985) | 3.15 |
Treatment with streptomycin, isonicotinic acid and/or para-aminosalicylic acid should be started as soon as genitourinary tuberculosis is proved. Treatment with strePTomycin plus bacitracin decreased the anaerobic bacterial levels in these gnotobiotic mice.
| Excerpt | Reference | Relevance |
|---|---|---|
| "In streptomycin-treated mice, the FCT was able to prevent C." | ( Diluted Fecal Community Transplant Restores Clostridioides difficile Colonization Resistance to Antibiotic-Perturbed Murine Communities. Bishop, L; Colovas, J; Henry, A; Lesniak, NA; McBride, K; Schloss, PD; Taylor, A; Tomkovich, S, 2022) | 1.24 |
| "For streptomycin-pretreated mice, which were colonized with higher levels of Salmonella, an additional gavage of arabinose was required to completely eliminate the vaccine bacteria in the guts of the tested mice." | ( Elimination of persistent vaccine bacteria of Salmonella enterica serovar Typhimurium in the guts of immunized mice by inducible expression of truncated YncE. Chen, Z; Cong, Y; Li, J; Tan, Y; Wang, Y; Xiong, K; Zheng, C, 2017) | 0.94 |
| "Streptomycin treatment eliminated Bartonella-like bacteria in the both A." | ( The effect of antibiotics on associated bacterial community of stored product mites. Hubert, J; Kopecky, J; Mareckova-Sagova, M; Nesvorna, M, 2014) | 1.12 |
| "Streptomycin treatment had little effect on the microbiota and on disease, whereas vancomycin reduced microbial diversity, shifted the composition of the bacterial population and enhanced disease severity." | ( Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. Blanchet, MR; Finlay, BB; Gill, N; Gold, MJ; Hartmann, M; McNagny, KM; Mohn, WW; Russell, SL; Thorson, L; Willing, BP; Wlodarska, M, 2012) | 1.1 |
| "Streptomycin-pretreated mice provide an alternative animal model to study enteric salmonellosis." | ( Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice. Hapfelmeier, S; Hardt, WD; Kremer, M; Müller, C; Stallmach, T; Stecher, B, 2004) | 1.25 |
| "Streptomycin is the treatment of choice in developing countries for patients suffering from tuberculosis or other infectious diseases. " | ( Streptidine, a metabolic derivative produced after administration of streptomycin in vivo, is vestibulotoxic in rats. Granados, O; Meza, G, 2005) | 2.01 |
| "Streptomycin pretreated mice provide a surrogate host model for studying molecular aspects of the intestinal inflammation (colitis) caused by serovar Typhimurium (S." | ( Virulence of broad- and narrow-host-range Salmonella enterica serovars in the streptomycin-pretreated mouse model. Barrow, PA; Hapfelmeier, S; Hardt, WD; Jantsch, J; Kremer, M; Stallmach, T; Suar, M, 2006) | 1.28 |
| "Streptomycin treatment resulted in improved experimental colonization variables, compared with untreated controls, during initiation (days 2 to 6) and early maintenance (days 7 to 12) of colonization. " | ( Evaluation of a model for Escherichia coli O157:H7 colonization in streptomycin-treated adult cattle. Blair, JL; Clinkenbeard, KD; Cohen, PS; Conway, T; Fabich, AJ; Sims, WP; Snider, TA; Washburn, KE, 2006) | 2.01 |
| "Streptomycin is still the treatment of choice for tularemia and plague, and is effective in a few other diseases. " | ( Proper use of aminoglycosides. Yoshikawa, TT, 1980) | 1.7 |
| "This streptomycin sulfate treatment procedure, however, had no effect on the reactive carbonyl measurement of an oxidized protein sample." | ( Protein oxidation and aging. I. Difficulties in measuring reactive protein carbonyls in tissues using 2,4-dinitrophenylhydrazine. Cao, G; Cutler, RG, 1995) | 0.75 |
| "In streptomycin-treated guinea pigs, immunoreactivities for NFP and vimentin (found in the hair cells) decreased after treatment, whereas immunoreactivities for the other IFs were not affected.(ABSTRACT TRUNCATED AT 250 WORDS)" | ( Immunocytochemical localization of intermediate filaments in the guinea pig vestibular periphery with special reference to their alteration after ototoxic drug administration. Fujita, S; Hozawa, J; Matsubara, A; Saito, S; Shinkawa, H; Usami, S, 1993) | 0.8 |
| "Streptomycin-treated adult mice were investigated as a possible model for studying the enteropathogenicity of Aeromonas species. " | ( Colonization of streptomycin-treated mice by Aeromonas species. Ghazali, FM; Kirov, SM; Sanderson, K, 1996) | 2.08 |
| "Streptomycin-treated rats exhibited almost complete destruction of sensory hair cells in the crista ampullaris, vestibular impairment in the drop test, and hyperkinesia." | ( Dizocilpine attenuates streptomycin-induced vestibulotoxicity in rats. Basile, AS; Brichta, AM; Coling, D; Harris, BD; Morse, D; Skolnick, P, 1999) | 1.34 |
| "When streptomycin-treated, strobe-recovered birds were then placed in normal light for 2 days, hVOR gain returned to normal." | ( Visual influences on the development and recovery of the vestibuloocular reflex in the chicken. Fuchs, AF; Goode, CT; Maney, DL; Rubel, EW, 2001) | 0.77 |
| "A streptomycin-treated mouse model was used to compare the intestinal colonizing capacity of E." | ( Mouse model for colonization and disease caused by enterohemorrhagic Escherichia coli O157:H7. Burris, JA; O'Brien, AD; Wadolkowski, EA, 1990) | 0.84 |
| "In streptomycin-treated guinea pigs with damage to the ampullary hair cells, the situation was reversed: the AEP responded normally while the CEP responded abnormally." | ( Origin of the endolymphatic DC potential in the cochlea and ampulla of the guinea pig. Ono, T; Tachibana, M, 1990) | 0.79 |
| "Streptomycin treatment on either Days 2 to 12 or Days 8 to 13 abolished the transepithelial potential difference and short-circuit current across the monolayer but had no effect on transepithelial resistance in confluent 12 to 13-d cultures, suggesting the loss of active transepithelial transport." | ( Streptomycin toxicity in primary cultures of flounder renal proximal tubule cells. Dickman, KG; Renfro, JL, 1990) | 2.44 |
| "Both streptomycin-treated and untreated Swiss white mice were irregularly colonized when challenged orogastrically with between 1 and 10(11) viable organisms of either of two strains of Campylobacter jejuni. " | ( Colonization of mice by Campylobacter jejuni. Hentges, DJ; Jesudason, MV; Pongpech, P, 1989) | 0.79 |
| "Streptomycin treatment in Menière's disease has traditionally been used for control of vertigo in patients with severe bilateral involvement or unilateral involvement in the only hearing ear. " | ( Streptomycin treatment in Menière's disease. Emmett, JR; Moretz, WH; Orchik, DJ; Shea, JJ, 1987) | 3.16 |
| "When streptomycin-treated and untreated mice were challenged orogastrically with 10(3) viable S." | ( Effect of streptomycin administration on colonization resistance to Salmonella typhimurium in mice. Hentges, DJ; Que, JU, 1985) | 1.13 |
| "Treatment with streptomycin enhances the growth of human commensal Escherichia coli isolates in the mouse intestine, suggesting that the resident microbial community (microbiota) can inhibit the growth of invading microbes, a phenomenon known as "colonization resistance." However, the precise mechanisms by which streptomycin treatment lowers colonization resistance remain obscure. " | ( Streptomycin-induced inflammation enhances Escherichia coli gut colonization through nitrate respiration. Bäumler, AJ; Kingsbury, DD; Lopez, CA; Spees, AM; Tsolis, RM; Wangdi, T; Winter, SE; Xavier, MN, 2013) | 2.19 |
| "Treatment with streptomycin increased misreading errors at several codons associated in particular with U·U, G·U and C·U codon·anti-codon mismatches, but oxidative stress did not change translational fidelity." | ( Translational misreading in Mycobacterium smegmatis increases in stationary phase. Javid, B; Leng, T; Pan, M; Xu, X, 2015) | 0.76 |
| "Treatment with streptomycin resulted in the loss of most Pax2 immunoreactivity from the lumenal (hair cell) stratum of the utricle." | ( Expression of the Pax2 transcription factor is associated with vestibular phenotype in the avian inner ear. Richardson, GP; Warchol, ME, ) | 0.47 |
| "Upon treatment with streptomycin, substantial changes in the microbial composition occurred, with a marked loss of population complexity." | ( Perturbation of the small intestine microbial ecology by streptomycin alters pathology in a Salmonella enterica serovar typhimurium murine model of infection. Altier, C; Antonopoulos, DA; Duhamel, GE; Garner, CD; Keresztes, I; Ross, DA; Wagner, B; Young, VB, 2009) | 0.91 |
| "Pretreatment with streptomycin (500 mg twice daily) showed similar results." | ( Inhibitory effect of arsenic on aerobic gut flora in rat. Choudhry, ZK; Hosain, AK; Misbahuddin, M; Saleh, AA, 2009) | 0.68 |
| "Treatment with streptomycin, isonicotinic acid and/or para-aminosalicylic acid should be started as soon as genitourinary tuberculosis is proved." | ( Current views on genitourinary tuberculosis. MALCOLM, DC, 1954) | 0.57 |
| "Treatment with streptomycin plus bacitracin decreased the anaerobic bacterial levels in these gnotobiotic mice, allowing increased population levels of E." | ( Inhibition of Escherichia coli translocation from the gastrointestinal tract by normal cecal flora in gnotobiotic or antibiotic-decontaminated mice. Berg, RD, 1980) | 0.6 |
| "Pretreatment with streptomycin at a low concentration influenced the susceptibility to streptomycin of a strain of Escherichia coli carrying a streptomycin-resistance plasmid, pSA1700, derived from Pseudomonas aeruginosa. " | ( Isolation of an Escherichia coli mutant which permits the high-level expression of a streptomycin-resistance gene derived from Pseudomonas aeruginosa. Arai, T; Hamashima, H; Kazama, H; Sasatsu, M, 1998) | 0.86 |
| "Pretreatment with streptomycin (200 micromol/L) not only eliminated the facilitated effect of ado on carotid baroreflex but also caused a reflex decrease in MAP to a level lower than control." | ( [Streptomycin inhibits carotid sinus baroreflex in anesthetized rats]. Chen, S; He, RR; Yin, T, 2000) | 1.54 |
| "Treatment with streptomycin, sulfamethoxazole and trimethoprim achieved the clinical and roentgenologic cure of the patient." | ( [Pulmonary nocardiosis. A case report (author's transl)]. García Rodríguez, JA; Martín Luengo, F; Villar Galán, JL, 1979) | 0.6 |
| "Treatment with streptomycin but not with neomycin led to impaired order of arm entries." | ( Impaired tunnel-maze behavior in rats with sensory lesions: vestibular and auditory systems. Classen, W; FitzGerald, RE; Krinke, G; Schaeppi, U, 1991) | 0.62 |
| "coli treated with streptomycin." | ( Error propagation in E. coli protein synthesis. Blomberg, C; Johansson, J; Liljenström, H, 1985) | 0.59 |
In a series of 1,212 tuberculosis patients treated on a regime of streptomycin/isoniazid/thiacetazone over a period of 10 years in Nigeria there were 171 cases considered to have toxic reactions. In a dose of 1/10 or 1/5 of the LD50 injected intraperitoneally CPP lowered acute toxicity of strepomycin.
| Excerpt | Reference | Relevance |
|---|---|---|
| "In a series of 1,212 tuberculosis patients treated on a regime of streptomycin/isoniazid/thiacetazone (S/INH/thiacetazone) over a period of 10 years in Nigeria there were 171 cases considered to have toxic reactions to thiacetazone (14%)." | ( Thiacetazone toxicity in the treatment of tuberculosis patients in Nigeria. Pearson, CA, 1978) | 0.5 |
| " An additive toxic effect was obvious in patients receiving streptomycin; when the treatment was withdrawn the urinary NAG activity stabilized within 15-21 days." | ( Detection of rifampicin-induced nephrotoxicity by N-acetyl-3-D-glucosaminidase activity. Krishnaswamy, K; Kumar, BD; Prasad, CE, 1992) | 0.53 |
| "An analysis of the adverse effects appearing in 101 patients during at least 4 months of chemotherapy for newly detected pulmonary tuberculosis between September, 1985 and July, 1987 was performed." | ( Adverse effects of antitubercular drugs and significance of measurement of the drug-stimulating lymphocyte transformation rate. Umeki, S, ) | 0.13 |
| " The subconfluent cultures demonstrated increased resistance to the toxic effects of streptomycin, again mimicking the clinical experience with aminoglycoside toxicity." | ( Cultured human proximal tubule cells as a model for aminoglycoside nephrotoxicity. Blackburn, JG; Hazen-Martin, DJ; Hennigar, GR; Sens, DA; Sens, MA, ) | 0.36 |
| " This association of toxic reactions with antibodies is highly significant (P<0." | ( Potentially serious side effects of high-dose twice-weekly rifampicin. Poole, G; Stradling, P; Worlledge, S, 1971) | 0.25 |
| "Pyrazinamide, an antituberculous drug discovered in 1952, was first considered as a toxic drug." | ( [Toxicity of pyrazinamide in antituberculous treatments (author's transl)]. Perdrizet, S; Pretet, S, 1980) | 0.26 |
| "The adverse effects of drugs which caused changes in therapeutic regimens have been studied in 511 patients with pulmonary tuberculosis, at the Pavilion Koch of Buenos Aires University." | ( Adverse effects of antituberculosis drugs causing changes in treatment. Dambrosi, A; Dambrosi, VM; Gonzalez Montaner, LJ; Manassero, M, 1982) | 0.26 |
| " These cases plus similar reports in the literature suggest that isoniazid or rifampin, or both, may potentiate the hepatotoxicity of acetaminophen, perhaps by induction of cytochrome P450 isozymes that oxidize acetaminophen to its toxic metabolites." | ( Hepatotoxicity associated with acetaminophen usage in patients receiving multiple drug therapy for tuberculosis. Nelson, SD; Nolan, CM; Sandblom, RE; Slattery, JT; Thummel, KE, 1994) | 0.29 |
| " This study supports the idea that iron and free radicals play a critical role in the toxic side effects of aminoglycoside antibiotics." | ( Iron chelators protect from aminoglycoside-induced cochleo- and vestibulo-toxicity. Schacht, J; Sha, SH; Song, BB, 1998) | 0.3 |
| " Group II also registered; the maximum cost and highest incidence of adverse effects." | ( Comparative evaluation of efficacy and safety profile of three anti-tuberculous regimens in Mangalore. Beena, S; Pai, MR; Rao, KN, 2002) | 0.31 |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | ( Developing structure-activity relationships for the prediction of hepatotoxicity. Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) | 0.36 |
| " The study will be useful in promoting effective residue monitoring and ensuring safe use of these antibiotics in managing bacterial diseases of pomegranate." | ( Validation of a residue analysis method for streptomycin and tetracycline and their food safety evaluation in pomegranate (Punica granatum L.). Banerjee, K; Jadhav, MR; Oulkar, DP; Sabale, R; Shabeer T P, A; Utture, SC, 2013) | 0.65 |
| " Based on our results it can be concluded that the FB control measures currently applied in Switzerland are safe for consumers, workers and the environment." | ( Fire Blight Control: The Struggle Goes On. A Comparison of Different Fire Blight Control Methods in Switzerland with Respect to Biosafety, Efficacy and Durability. Gusberti, M; Hunger-Glaser, I; Klemm, U; Maurhofer, M; Meier, MS, 2015) | 0.42 |
The efficacies of simulated pharmacokinetic profiles for human 10-day clinical regimens of ampicillin, meropenem, moxifloxacin and gentamicin were compared with the gold standard, streptomycin, for killing of Yersinia pestis.
Oxytetracycline (OTC) combined with streptomycin (STM) eliminated Brucella melitensis from 480 naturally-infected sheep and goats. The extent of synergistic killing and duration of the post-antibiotic effect was evaluated.
| Excerpt | Reference | Relevance |
|---|---|---|
| "The effect of streptomycin used alone and in combination with tubazid on the brain electric activity was studied in chronic experiments on rabbits with tuberculosis." | ( [Effect of the prolonged use of streptomycin as well as streptomycin in combination with tubazid on the bioelectrical activity of the brain in experimental tuberculosis]. Aksel'rod, LB; Bogun, OI; Kniazheva, VN; Sukolovskaia, DM, 1976) | 0.9 |
| "Six treatment regimens using oxytetracycline (OTC) combined with streptomycin (ST) were evaluated for eliminating Brucella melitensis from 480 naturally-infected sheep and goats." | ( Treatment of Brucella melitensis infection in sheep and goats with oxytetracycline combined with streptomycin. Bekairi, SI; Mukayel, AA; Radwan, AI, 1992) | 0.74 |
| "Twenty-four rams inoculated with Brucella ovis by conjunctival and preputial routes were treated with a long-acting oxytetracycline alone or in combination with dihydrostreptomycin sulfate." | ( Efficacy of long-acting oxytetracycline alone or in combination with streptomycin for treatment of Brucella ovis infection of rams. Barberán, M; Blasco, JM; Jiménez de Bagués, MP; Marín, CM, 1989) | 0.71 |
| "The efficacy of oxytetracycline (OTC) alone or combined with streptomycin in the treatment of 118 Najdi ewes believed to have been naturally infected with Brucella melitensis, was evaluated by culture of selected tissues and organs at slaughter." | ( Experimental treatment of Brucella melitensis infection in sheep with oxytetracycline alone or combined with streptomycin. al-Aska, AK; al-Jalaifi, M; al-Mukayel, AA; al-Yamani, MJ; Bekairi, SI; Hafez, SM; Radwan, AI, 1989) | 0.73 |
| "Seven strains of Streptococcus faecalis, of which two possessed high-level resistance to streptomycin (MIC greater than or equal to 2000 mcg/ml), and two strains of Streptococcus faecium were evaluated with respect to killing-effect and duration of post-antibiotic effect (PAE) of ampicillin and vancomycin in combination with streptomycin, gentamicin, tobramycin and netilmicin." | ( Evaluation of the combination effects of ampicillin or vancomycin combined with streptomycin, gentamicin, tobramycin or netilmicin against enterococci. Fuursted, K, 1989) | 0.73 |
| "Twenty-nine Brucella abortus culture-positive cows were treated with a long-acting oxytetracycline (20 mg/kg of body weight, IM) alone or combined with streptomycin (25 mg/kg, IM or IV) or were re-treated with the same product." | ( Efficacy of long-acting oxytetracycline alone or combined with streptomycin in the treatment of bovine brucellosis. Altvater, L; Hoffmann, E; Milward, FW; Nicoletti, P, 1985) | 0.71 |
| " At achievable serum concentrations, ampicillin alone killed 60% of strains, whereas combination with streptomycin increased this to 90% and with gentamicin to 100%." | ( In vitro activity of ampicillin or vancomycin combined with gentamicin or streptomycin against enterococci. Guze, LB; Harwick, HJ; Kalmanson, GM, 1973) | 0.7 |
| " melitensis intraperitoneally on day 0 and were randomized to receive, starting on day 7, STR alone at 75, 150, or 300 mg/kg of body weight per day intraperitoneally or DOX at 6 mg/kg/day orally, RIF at 3 mg/kg/day orally, or CIP at 200 mg/kg/day orally, each of the last three drugs alone or in combination with STR at 75, 150, or 300 mg/kg/day, for 14 days." | ( Therapy of experimental murine brucellosis with streptomycin alone and in combination with ciprofloxacin, doxycycline, and rifampin. Lang, R; Rubinstein, E; Shasha, B, 1993) | 0.54 |
| "The efficacy of vancomycin (VM) and teicoplanin (TE), alone and in combination with streptomycin (SM), against enterococci that express low-level VanB-type VM resistance was investigated in experimental endocarditis using isogenic strains of Enterococcus faecalis susceptible to glycopeptides and aminoglycosides or inducibly resistant to low levels of VM (MIC = 16 micrograms/ml)." | ( Efficacy of vancomycin and teicoplanin alone and in combination with streptomycin in experimental, low-level vancomycin-resistant, VanB-type Enterococcus faecalis endocarditis. Cooper, BW; Courvalin, P; Marangos, MN; Nicolau, DP; Nightingale, CH; Patel, KB; Quintiliani, R, 1996) | 0.75 |
| " The aim of this study was to ascertain whether DCL used in combination with the first-line antitubercular antibiotic streptomycin (STM) synergistically augments its efficacy in vitro as well as in a murine tuberculosis infection model." | ( Activity of diclofenac used alone and in combination with streptomycin against Mycobacterium tuberculosis in mice. Dastidar, SG; Dutta, NK; Mazumdar, K; Park, JH, 2007) | 0.79 |
| "To establish a method for the determination of streptomycin in honey by determined hydrophilic interaction chromatography combined with tandem mass spectrometry (HILIC-MS/MS)." | ( [Determination of streptomycin in honey determined by hydrophilic interaction chromatography combined with tandem mass spectrometry]. Chen, L; Ma, A; Zhou, Z, 2010) | 0.95 |
| " Ultimately, the good permeability, moderate rates of metabolism and low risk of drug-drug interactions displayed by some of the synthesized compounds indicate that 2-(quinolin-4-yloxy)acetamides may yield candidates to use in the development of novel alternative therapeutics for tuberculosis treatment." | ( New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis. Abbadi, BL; Back, DF; Basso, LA; Campos, MM; Giacobbo, BC; Grams, ES; Machado, P; Pissinate, K; Rodrigues-Junior, V; Santos, DS; Sperotto, N; Subtil, FT; Trindade, RV; Villela, AD, 2017) | 0.46 |
| "To analyze the effect of streptomyces protease combined with dyclonine in painless magnifying endoscopy." | ( Case report: Streptomycin combined with dacronin in painless magnifying endoscopy. Zhou, Z, 2023) | 1.28 |
| "The diagnoses were made by painless magnifying endoscopy and narrow-band imaging combined with pathological findings." | ( Case report: Streptomycin combined with dacronin in painless magnifying endoscopy. Zhou, Z, 2023) | 1.28 |
| "The patients were divided into the observation group and control group, the observation group was streptomyces protease combined with dyclonine group, and the control group was dyclonine group, 50 cases in each group." | ( Case report: Streptomycin combined with dacronin in painless magnifying endoscopy. Zhou, Z, 2023) | 1.28 |
| "Compared with the control group, the streptomyces protease combined with dyclonine group had better clear visibility and a higher detection rate of small lesions, but there was no significant difference in early cancer detection rate between the 2 groups." | ( Case report: Streptomycin combined with dacronin in painless magnifying endoscopy. Zhou, Z, 2023) | 1.28 |
| "Streptomyces protease combined with dyclonine plays a certain role in painless magnifying gastroscopy, which can improve the visibility of gastroscopy, improve the detection rate of small lesions, help to find gastric dysplasia and early gastric cancer diagnosis, and does not increase the incidence of adverse reactions." | ( Case report: Streptomycin combined with dacronin in painless magnifying endoscopy. Zhou, Z, 2023) | 1.28 |
There was a 21-fold increase in the relative bioavailability of PLG-encapsulated streptomycin compared with intramuscular free drug.
Streptomycin and vitamin K3 were studied on the guinea-pig ileum for their effects on the cumulative dose-response curves of bradykinin, acetylcholine and histamine. Bilateral labyrinthectomy or prolonged dosage was found to nearly abolish the counterroll reflex.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the second group, the dosage of each antibiotic necessary to induce apnea is sought." | ( [Neuromuscular inhibition of new aminoglycoside antibiotics]. Baltar, I; Esplugues, J; Marti, JL; Orts, A, 1979) | 0.26 |
| " But this effect is small and does not justify a change in the usual dosage of rifampicin." | ( [The use of mycobacteria in the estimation of the concentration of antibiotics, antimycotics and antituberculotics (author's transl)]. Iwainsky, H; Reutgen, H; Sesser, I, 1978) | 0.26 |
| " Basing their comment on the published literature, they analyze the properties, pharmacology, toxicity, and side-effects of each medication, and define their dosage and modes of administration." | ( [Principles underlying the use of antituberculosis medication in children (author's transl)]. Besson-Leaud, M; Ollivier, A, ) | 0.13 |
| " As regards the influence of gentamicin on cell growth and metabolsim, dose-response relationship were found proving that the antibiotic causes a depression of proliferation, a striking increase in lactate production, an elevated LDH release, and changes in pH behaviour." | ( Gentamicin as a bactericidal antibiotic in tissue culture. Fischer, AB, 1975) | 0.25 |
| " The influence of dosage and renal function on serum levels and their relevance to ototoxicity are discussed." | ( Suggestions for monitoring patients during treatment with aminoglycoside antibiotics. Lerner, SA; Matz, GJ, ) | 0.13 |
| " It rests on an optimum dosage in connection with a best suited combination, taking into consideration the relations of sensitiveness and side effects as well as consequent long-term treatment." | ( [Modern therapy and after-care in urogenital tuberculosis]. Kalweit, H; Lenk, S; Rothkopf, M, 1978) | 0.26 |
| " The low dose-response curves obtained presenting no significant deviation from parallelism are highly suggestive of a competitive type of antagonism between those substances." | ( Competitive antagonism between calcium and antibiotics at the neuromuscular junction. Corrado, AP; Marseillan, RF; Prado, WA, 1978) | 0.26 |
| " The patient's cooperation during a systematic triple drug therapy in adequate dosage is important." | ( [Present status and treatment of urogenital tuberculosis]. Haubensak, K; Osterhage, HR, 1975) | 0.25 |
| " Bilateral labyrinthectomy or prolonged dosage with streptomycin was found to nearly abolish the counterroll reflex." | ( Effect of labyrinthectomy on the dynamic vestibulo-ocular counterrol reflex in the rhesus monkey. Hite, D; Hyams, VJ; Junker, AM; Smiles, KA, 1975) | 0.51 |
| "Indications, side effects, dosage and several pharmacokinetic properties of gentamicin, tobramycin, sisomicin, kanamycin, amikacin, and streptomycin are delt with in the first part." | ( [Aminoglycoside antibiotics from clinical viewpoint]. Lüthy, R, 1975) | 0.46 |
| " In a second series of 27 orthotopic liver transplantations in tissue-typed littermate dogs and littermate pigs the standard surgical technique and aftercare were changed with regard to four factors: an end-to-end common bile duct anastomosis was made instead of a gallbladder to duodenum anastomosis; the continuous postoperative bacteriostatic antibiotic therapy was changed to a single 2-day course of bactericidal antibiotics; preoperative selective bowel decontamination combined with postoperative protective isolation was introduced; the dosage of azathioprine used for immunosuppression was reduced." | ( Orthotopic liver transplantation: an experimental study on the prevention of infections with Gram-negative organisms. Hendriks, WD; Jerusalem, C; Krom, RA; Popescu, DT; Schalm, SW; Terpstra, JL; Van Der Waay, D, 1975) | 0.25 |
| " The administration of isoniazid in standard dosage for one year in these situations will help greatly to reduce tuberculosis as a community health problem in the future." | ( The Jewish Hospital of St. Louis therapeutic grand rounds number 10. Chemoprophylaxis of tuberculosis. Avioli, LV; Byrd, R; Lefrak, SS; Senior, RM, 1975) | 0.25 |
| " The highest antibiotic dosage induced an abrupt decline of PGI2 synthesis, down to 26%, in animals with the longest duration of treatment." | ( Prostaglandin synthesis by the lateral cochlear wall under streptomycin influence. Aharinejad, S; Firbas, W; Franz, P; Sinzinger, H, 1992) | 0.53 |
| " The first group received intramuscular injection of streptomycin sulfate 400 mg/kg/day for one week; the second group received the same dosage for two weeks; the third group served as the control." | ( [Streptomycin toxicity on dark cells of utricles in guinea pigs]. Ge, X, 1991) | 1.44 |
| " The dosage schedule used involved two intraperitoneal administrations of SPLV-entrapped aminoglycosides at three-day intervals." | ( Treatment of Brucella canis and Brucella abortus in vitro and in vivo by stable plurilamellar vesicle-encapsulated aminoglycosides. Fountain, AG; Fountain, MW; Lenk, RP; Shen, A; Weiss, SJ, 1985) | 0.27 |
| " Drug-localization studies demonstrated that significant fractions of the total dosage were associated with the red-cell membrane." | ( The effects of antibiotics on hemolytic behavior of red cells. Lijana, RC; Williams, MC, 1986) | 0.27 |
| " Based on the gene dosage effect and the biological characteristics of the mutants complemented by strR and strB, it was concluded that strB encodes amidinotransferase and strR encodes a positive effector required for the full expression of strA and strB genes." | ( Self-cloning in Streptomyces griseus of an str gene cluster for streptomycin biosynthesis and streptomycin resistance. Aiba, S; Imanaka, T; Ohnuki, T, 1985) | 0.51 |
| " These results suggest that lower dosage of streptomycin in the therapy of enterococcal infections will probably result in a higher relapse rate." | ( Synergistic effect of ampicillin or vancomycin in combination with decreasing concentrations of streptomycin against enterococci. Fuursted, K, 1988) | 0.75 |
| " In studies relating cell numbers to the dosage and time of exposure to streptomycin, the confluent cultures demonstrated and "insult-recovery" period at toxic, but sub-lethal, concentration, again correlating to the known in vivo experience with this class of antibiotics." | ( Cultured human proximal tubule cells as a model for aminoglycoside nephrotoxicity. Blackburn, JG; Hazen-Martin, DJ; Hennigar, GR; Sens, DA; Sens, MA, ) | 0.36 |
| " It should be emphasized, however, that the standard dosage of aminoglycosides in patients with cystic fibrosis frequently results in serum concentrations that are lower than anticipated because of a relatively larger volume of drug distribution and a greater urinary excretion rate." | ( Aminoglycoside toxicity in infants and children. McCracken, GH, 1986) | 0.27 |
| "The bactericidal activity of the aminoglycoside antibiotics streptomycin and kanamycin for Mycobacterium leprae in mice was assessed, both alone and in combination with rifampin, utilizing various dosage schedules." | ( Further studies of the killing of M. leprae by aminoglycosides: reduced dosage and frequency of administration. Gelber, RH, 1987) | 0.52 |
| " In the first study, when isoniazid was prescribed daily in a dosage of 20 mg/kg, 39% of the patients developed jaundice; however, when the dosage was reduced to 12 mg/kg, the incidence fell to 16%." | ( Three chemotherapy studies of tuberculous meningitis in children. Duraipandian, M; Nagarajan, M; Prabhakar, R; Ramachandran, P; Ramakrishnan, CV; Tripathy, SP, 1986) | 0.27 |
| " Current dosage recommendations are based on total body weight (TBW); drug toxicity might result in obese patients receiving TBW doses." | ( Dosage of antituberculous drugs in obese patients. Geiseler, PJ; Maddux, MS; Manis, RD, 1985) | 0.27 |
| " No functional or histopathologic evidence of ototoxicity was found in any neonatal rat dosed with aztreonam or saline." | ( Ototoxicity of subcutaneously administered aztreonam in neonatal rats. DePaoli, A; Keim, GR; Myhre, JL, 1985) | 0.27 |
| "A patient with Addison's disease required increased corticosteroid dosage whilst receiving rifampicin." | ( Changes in cortisol metabolism following rifampicin therapy. Courtenay-Evans, RJ; Edwards, OM; Galley, JM; Hunter, J; Tait, AD, 1974) | 0.25 |
| " Complaints of vomiting or diarrhoea that did not require a reduction of the PAS dosage were made on one or two occasions by 23(21%) out of 109 twice-weekly and 25 (23%) out of 108 daily patients, and on at least three occasions by 4 (4%) and 12 (11%) respectively." | ( Controlled comparison of oral twice-weekly and oral daily isoniazid plus PAS in newly diagnosed pulmonary tuberculosis. , 1973) | 0.25 |
| " The effects of 4 antibiotics orally administered in varying dosage schedules were studied." | ( Antibiotic therapy of cholera. Greenough, WB; Islam, MR; Lindenbaum, J, 1967) | 0.25 |
| " They were then allocated at random either to standard daily continuation chemotherapy with isoniazid plus PAS or to fully supervised treatment with streptomycin and high dosage isoniazid, given twice weekly." | ( A comparative study of daily and twice-weekly continuation regimens of tuberculosis chemotherapy, including a comparison of two durations of sanatorium treatment. 1. First report: the results at 12 months. , 1971) | 0.45 |
| " The kinetics of DNA uptake, dose-response curve of DNA versus transformants, time required for phenotypic expression, and other features were similar to those in other bacterial transformation systems." | ( Genetic transformation of Neisseria gonorrhoeae to streptomycin resistance. Sparling, PF, 1966) | 0.5 |
| " The results confirm that the twice-weekly regimen is highly effective and demonstrate that its efficacy is not influenced by the rate of inactivation of isoniazid or by a reduction (by one-fourth) in the dosage of streptomycin." | ( A controlled comparison of a twice-weekly and three once-weekly regimens in the initial treatment of pulmonary tuberculosis. , 1970) | 0.43 |
| " A good dose-response relationship was evident." | ( Suppressive activity of streptomycin on the growth of Mycobacterium lepraemurium in macrophage cultures. Chang, YT, 1969) | 0.55 |
| " Used in high dosage by the intraventricular as well as the intravenous route, this drug might be successful in the treatment of further cases of primary amoebic meningoencephalitis." | ( Sensitivity to amphotericin B of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis. Carter, RF, 1969) | 0.25 |
| " Although HPO alone is primarily bacteriostatic, combined therapy with antibiotics and HPO may be useful against bacterial infections because the therapeutic effectiveness of a maximal dosage of antibiotic could be increased." | ( Enhancement of antibiotic activity against Staphylococcus aureus by exposure to hyperbaric oxygen. Bornside, GH, 1967) | 0.25 |
| " The liposomal preparations thus formed may be useful as intravenous dosage forms of the antibiotics." | ( [Production of liposomal preparations of streptomycin and dihydrostreptomycin]. Griazmova, NS; Ladygina, GA; Petiushenko, RM; Tentsova, AI; Vladimirskiĭ, MA, 1984) | 0.53 |
| " These studies are the first to test and satisfy the interpretation of a dose-response curve for animal survival in terms of "target cell" survival, where measurements of both are made over a similar range of dose in concurrent experiments." | ( The gastrointestinal syndrome and mucosal clonogenic cells: relationships between target cell sensitivities, LD50 and cell survival, and their modification by antibiotics. Hendry, JH; Potten, CS; Roberts, NP, 1983) | 0.27 |
| " In spite of therapy with penicillin G and gentamycin in high dosage the patient got centralnervous spasms and died on the second day." | ( [Listeriosis: case report and repetitorium]. Franzen, H; Just, I; Ringelmann, R; Stegmüller, B, 1984) | 0.27 |
| " Prescribed at a daily dosage of 30 to 35 mg/kg (1,5 to 2 g daily), it gives no major side effects." | ( [Toxicity of pyrazinamide in antituberculous treatments (author's transl)]. Perdrizet, S; Pretet, S, 1980) | 0.26 |
| " This increase was independent of dosage of ethambutol." | ( Hyperuricaemia induced by ethambutol. Agarwal, MC; Bihari, K; Narang, RK; Raina, AK; Sharma, SN; Singh, SN, 1983) | 0.27 |
| " When recommended dosage regiments are followed, the incidence of adverse reactions is low with short-course therapy, and in only 5% or less of patients is it necessary to withdraw one or more drugs." | ( Short-course therapy for tuberculosis. Aquinas, M, 1982) | 0.26 |
| " First, some birds in the three experimental groups began to tremble at least slightly by the third injections, but others, particularly at the highest dosage (1,200 mg/kg body weight), trembled severely by the fifth injections." | ( Vestibular ototoxicity in the chick: effects of streptomycin on equilibrium and on ampullary dark cells. Cohen, GM; Park, JC, ) | 0.39 |
| "The agonistic actions of angiotensin II and prostaglandin E2 (PGE2) were plotted on the guinea-pig ileum as cumulative dose-response curves." | ( Non-competitive inhibition of angiotensin II and PGE2 on guinea-pig ileum with streptomycin, vitamin K3 and rutin. Abacioglu, N; Altinkurt, O, 1980) | 0.49 |
| " A dosage interval of 8 h would be appropriate for kanamycin compared with a 12-h interval for streptomycin." | ( The pharmacokinetics of some aminoglycoside antibiotics in the horse. Baggot, JD; Love, DN; Raus, J; Rose, RJ, 1981) | 0.48 |
| "Streptomycin and vitamin K3 were studied on the guinea-pig ileum for their effects on the cumulative dose-response curves of bradykinin, acetylcholine and histamine." | ( Non-competitive inhibition of bradykinin, acetylcholine and histamine on guinea-pig ileum with streptomycin and vitamin K3. Altinkurt, O; Kanzik, I, 1980) | 1.92 |
| " Diazepam displaced the dose-response curve to the right in four cats." | ( Interaction between rocuronium bromide and some drugs used during anaesthesia. Anderson, KA; Muir, AW; Pow, E, 1994) | 0.29 |
| "310 patients with pulmonary tuberculosis disseminating bacteria received isoniazid, rifampicin, streptomycin (ethambutol) and pirazinamid in different regimens and dosage forms." | ( [Combined chemotherapy of patients with tuberculosis - new regimens and dosage forms]. Elistratova, NA; Khalbaeva, IV; Koriakin, VA; Sokolova, GB; Ziia, AV, 1993) | 0.5 |
| " The findings of this study indicate that only a low dosage of streptomycin and a small volume of perfusate are required to obtain good results." | ( Factors influencing results with streptomycin perfusion of the labyrinth. Ge, X; Shea, JJ, 1993) | 0.81 |
| " The results indicate that streptomycin in a low dosage that will destroy the vestibular receptors was not harmful to the function of either the stria vascularis or the hair cells in the cochlea, as measured by changes in the EP after streptomycin perfusion of the cochlea." | ( Effect on endocochlear potential of streptomycin perfusion of the cochlea in guinea pigs. Ge, X; Liu, J; Shea, JJ, 1993) | 0.86 |
| " In order to destroy vestibular function and preserve cochlear function, further study for adequate dosage of streptomycin and correct route of administration is needed." | ( [Effect of streptomycin placing in the fenestra of semicircular canals on the function and morphology of the normal and hydropic ears in guinea pigs]. Chen, Z; Lu, Y; Peng, A, 1995) | 0.89 |
| " The dosage of streptomycin used for successful ablation of vertigo varied between 250 and 100 micrograms." | ( Selective chemical vestibulectomy. Preliminary results. Amedee, RG; Begall, K; Ecke, U; Mann, WJ; Norris, CH, ) | 0.48 |
| "Ten chinchillas underwent left middle ear instillation of one of three agents using variable dosing schedules: gentamicin (n = 6), streptomycin (n = 2), and saline (n = 2) as control." | ( Middle ear instillation of gentamicin and streptomycin in chinchillas: morphologic appraisal of selective ototoxicity. Chen, JM; Harrison, RV; Hirakawa, H; Kakigi, A; Mount, RJ, 1999) | 0.77 |
| " Increased damage was seen with increased dosage of each drug." | ( Comparison of vestibular and cochlear ototoxicity from transtympanic streptomycin administration. Cefaratti, LK; Ogata, Y; Slepecky, NB; Wanamaker, HH, 1999) | 0.54 |
| "A simple and highly sensitive method is proposed for the fluorimetric determination of streptomycin in dosage forms and in biological fluids." | ( Spectrofluorimetric determination of streptomycin in dosage forms and in spiked plasma using 9,10-phenanthraquinone. Belal, F; El Kerdawy, MM; El Wasseef, DR; El-Ashry, SM, 2001) | 0.81 |
| " The dose-response curves for each test did not deviate significantly from parallelism." | ( Antinociceptive potency of aminoglycoside antibiotics and magnesium chloride: a comparative study on models of phasic and incisional pain in rats. Machado Filho, EB; Prado, WA, 2002) | 0.31 |
| " Further studies with increased rifapentine dosage are necessary." | ( Rifapentine and isoniazid in the continuation phase of a 6-month regimen. Final report at 5 years: prognostic value of various measures. Chan, SL; Goodall, RL; Kam, KM; Mitchison, DA; Tam, CM, 2002) | 0.31 |
| " This study compared the incidences of toxicities associated with 2 recommended dosing regimens." | ( Aminoglycoside toxicity: daily versus thrice-weekly dosing for treatment of mycobacterial diseases. Berning, SE; Cook, JL; Curran-Everett, D; Goble, M; Huitt, GA; Iseman, MD; Nitta, AT; Peloquin, CA; Simone, PM, 2004) | 0.32 |
| " In those cases in which the diagnosis was established by blood culture, the in vitro sensitivity of the organism to penicillin was determined and penicillin then was administered by continuous intramuscular infusion in a dosage calculated to produce blood levels of penicillin four to five times that required for in vitro inhibition." | ( Subacute bacterial endocarditis; a report on 57 patients treated with massive doses of penicillin. GRIFFITH, GC; LEVINSON, DC, 1949) | 0.23 |
| " Piglets in the treatment group were orally dosed with PCE (10(10) cfu/mL) twice within 24 h of birth, at weaning, and 18-24 h post-weaning; control group piglets were dosed with sterile broth as a placebo." | ( Effect of porcine-derived mucosal competitive exclusion culture on antimicrobial resistance in Escherichia coli from growing piglets. Bailey, JS; Fedorka-Cray, PJ; Gray, JT; Jones, RD; Kim, LM, 2005) | 0.33 |
| " We have demonstrated from a rat model that intestinal beta-glucuronidase may play a key role in the development of CPT-11-induced delayed diarrhea by the deconjugation of the luminal SN-38 glucuronide, and the elimination of the intestinal microflora by antibiotics or dosing of TJ-14, a Kampo medicine that contains beta-glucuronidase inhibitor baicalin, exerted a protective effect." | ( Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea. Hagiwara, T; Kamataki, T; Kumazawa, E; Nagai, E; Onose, S; Takasuna, K; Watanabe, K; Yoshida, S, 2006) | 0.33 |
| "Our results suggest that nanoencapsulation might be useful for developing a suitable oral dosage form for streptomycin and perhaps for other antibiotics that are otherwise injectable." | ( Nanoparticle-based oral drug delivery system for an injectable antibiotic - streptomycin. Evaluation in a murine tuberculosis model. Khuller, GK; Pandey, R, 2007) | 0.78 |
| " We observed a moderate dose-response effect for thiabendazole, whereby spore count decreased as drug consumption increased." | ( Effect of four antimicrobials against an Encephalitozoon sp. (Microsporidia) in a grasshopper host. Johny, S; Whitman, DW, 2008) | 0.35 |
| " allosaccharophila were either negative or occurred randomly at low levels with respect to concentrations of the dosage consumed by the animals." | ( A mouse model for characterization of gastrointestinal colonization rates among environmental Aeromonas isolates. Lye, DJ, 2009) | 0.35 |
| " Therapy was performed according to regimens 3 and 1, by using individual dosage regimens depending on the extent and severity of a specific process, the presence of complications, and age-related features." | ( [Optimization of chemotherapy regimens in children with primary pulmonary tuberculosis]. Dovgaliuk, IF; Ovchinnikova, IuE; Starshinova, AA, 2009) | 0.35 |
| " The objective of this experiment is to assess the impacts of various dosing frequencies of the combination on its bactericidal and sterilizing activities against Mycobacterium ulcerans in mice." | ( Impacts of dosing frequency of the combination rifampin-streptomycin on its bactericidal and sterilizing activities against Mycobacterium ulcerans in mice. Aubry, A; Chauffour, A; Ibrahim, M; Jarlier, V; Ji, B; Robert, J, 2009) | 0.6 |
| "Therapeutic drug monitoring allows to determine the best dosage regimen adapted to each patient optimizing the therapeutic benefits, while minimizing the risk for side effects." | ( Determination of antituberculosis drug concentration in human plasma by MALDI-TOF/TOF. Ascenzi, P; Bevilacqua, N; Gullotta, F; Lauria, FN; Mancone, C; Notari, S; Pucillo, LP; Sergi, M; Tempestilli, M; Tripodi, M; Urso, R, 2010) | 0.36 |
| "A questionnaire regarding what antitubercular drugs, their dosage and for how long was asked to attending faculty in an International Conference on musculoskeletal infections." | ( A survey of prescribing pattern for osteoarticular tuberculosis: orthopaedic surgeons' and infectious disease experts' perspective. Agarwal, A; Arora, A; Kumar, S, 2009) | 0.35 |
| "Streptomycin has been available for over 60 years, yet optimal dosing in hemodialysis (HD) patients is not well defined." | ( A successful strategy for the use of synergistic intravenous streptomycin in a hemodialysis patient with refractory Enterococcus faecalis bacteremia. Belknap, R; Jenkins, TC; Swartwood, CJ; Young, H, 2011) | 2.05 |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | ( FDA-approved drug labeling for the study of drug-induced liver injury. Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) | 0.37 |
| " Average CAM dosage was increased from the early (517 mg/day) to the later (800 mg/day) period." | ( Relationship between clinical efficacy for pulmonary MAC and drug-sensitivity test for isolated MAC in a recent 6-year period. Abe, M; Kato, S; Kobashi, Y; Mouri, K; Obase, Y; Oka, M, 2012) | 0.38 |
| " A dosage effect relating the level of damage to the concentration of streptomycin was observed." | ( Ageing in Escherichia coli requires damage by an extrinsic agent. Chao, L; Peng, AY; Poon, AF; Rang, CU, 2012) | 0.61 |
| "The series is part of an ongoing randomised controlled trial assessing rechallenge dosing following TB-associated cutaneous ADR." | ( Multiple drug hypersensitivity reactions to anti-tuberculosis drugs: five cases in HIV-infected patients. Dheda, K; Lehloenya, RJ; Todd, G; Wallace, J, 2012) | 0.38 |
| " Based on pharmacokinetic/pharmacodynamic indexes reported for beta-lactams against other bacterial pathogens, a cumulative percentage of a 24-h period that the drug concentration exceeds the MIC under steady-state pharmacokinetic conditions (%TMIC) of 20 to 40% was achieved in mice using a suitable dosing regimen." | ( In vitro and in vivo efficacy of β-lactams against replicating and slowly growing/nonreplicating Mycobacterium tuberculosis. Ahuja, V; Balasubramanian, V; Balganesh, M; Bhattacharjee, D; Dinesh, N; Ganguly, S; Kumar, N; Panduga, V; Parab, M; Ramachandran, V; Reddy, J; Shandil, R; Sharma, S; Solapure, S; Vishwas, KG, 2013) | 0.39 |
| "Therapeutic drug monitoring (TDM) of second-line antituberculosis drugs would allow for optimal individualized dosage adjustments and improve drug safety and therapeutic outcomes." | ( Pharmacokinetics of Second-Line Antituberculosis Drugs after Multiple Administrations in Healthy Volunteers. Chung, JY; Jang, IJ; Jang, K; Lee, JH; Moon, SJ; Oh, J; Park, JS; Park, SI; Song, J; Yoon, J; Yu, KS, 2015) | 0.42 |
| " High dose streptomycin (6-8 g/d) remained the first practical strategy for controlling the progressive, vicious clinical circumstances for patients with pneumonic plague in the Plateau, as opposed to the routine dosage recommended by the World Health Organization." | ( Continuous hypoxia reduces the concentration of streptomycin in the blood. Chen, L; Gao, Z, 2018) | 1.13 |
| " Here, we compared the application of streptomycin dosed orally in microcontainers to dosage through drinking water." | ( Local Delivery of Streptomycin in Microcontainers Facilitates Colonization of Streptomycin-Resistant Escherichia coli in the Rat Colon. Bahl, MI; Boisen, A; Chassaing, B; Christfort, JF; Daniel, N; Guerra, P; Kamguyan, K; Kristensen, KA; Licht, TR; Nielsen, LH; Torp, AM; Zòr, K, 2022) | 1.33 |
| Role | Description |
|---|---|
| antimicrobial agent | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| antimicrobial drug | A drug used to treat or prevent microbial infections. |
| antibacterial drug | A drug used to treat or prevent bacterial infections. |
| protein synthesis inhibitor | A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. |
| bacterial metabolite | Any prokaryotic metabolite produced during a metabolic reaction in bacteria. |
| antifungal agrochemical | Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| streptomycins | |
| antibiotic antifungal drug | Any antibiotic antifungal agent used to treat fungal infections in humans or animals. |
| antibiotic fungicide | Any antibiotic antifungal agent that has been used as a fungicide. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Pathway | Proteins | Compounds |
|---|---|---|
| Streptomycin Action Pathway | 1 | 4 |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 39.8107 | 0.0112 | 12.4002 | 100.0000 | AID1030 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 17.7828 | 0.0355 | 20.9770 | 89.1251 | AID504332 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 70.7946 | 0.3548 | 28.0659 | 89.1251 | AID504847 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 (µMol) | 1,000.0000 | 0.4000 | 2.7500 | 8.6000 | AID1209456 |
| Bile salt export pump | Homo sapiens (human) | IC50 (µMol) | 1,000.0000 | 0.1100 | 7.1903 | 10.0000 | AID1209455; AID1443988 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 (µMol) | 1,800.0000 | 2.5000 | 4.2000 | 5.9000 | AID320706 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | MIC | 11.7400 | 1.5600 | 4.6983 | 9.4100 | AID1647340 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1174111 | Antimycobacterial activity against isoniazid, rifampin, ethambutol-resistant Mycobacterium tuberculosis after 7 days by microplate Alamar blue assay | 2015 | European journal of medicinal chemistry, Jan-07, Volume: 89 | Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis. |
| AID637085 | Antibacterial activity against Micrococcus luteus ATCC 9631 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID424613 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH287 harboring Ala655Glu mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID509470 | Antibacterial activity against Bacillus subtilis at 100 ug/mL | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID595281 | Antimicrobial activity against Salmonella typhi ATCC 25021 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, spectral, crystal structure and in vitro antimicrobial evaluation of imidazole/benzotriazole substituted piperidin-4-one derivatives. |
| AID449211 | Cytotoxicity against african green monkey Vero cells after 72 hrs | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation. |
| AID719316 | Antimicrobial activity against Bacillus subtilis NCIM 2999 at 10 ug/disc incubated for 24 hrs by agar disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID446151 | Antimycobacterial activity against rifampin-resistant Mycobacterium tuberculosis H37Rv after 16 to 24 hrs by microplate alamar | 2010 | Journal of medicinal chemistry, Jan-28, Volume: 53, Issue:2 | Rational design of 5-phenyl-3-isoxazolecarboxylic acid ethyl esters as growth inhibitors of Mycobacterium tuberculosis. a potent and selective series for further drug development. |
| AID209595 | Antibacterial activity against gram positive bacteria Streptococcus mutans was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID1565884 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 assessed as growth inhibition measured after 24 hrs by two-fold broth dilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | Design, synthesis and biological evaluation of novel diazaspiro[4.5]decan-1-one derivatives as potential chitin synthase inhibitors and antifungal agents. |
| AID521803 | Antimicrobial activity against Francisella tularensis subsp. holarctica after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | In vitro susceptibility of isolates of Francisella tularensis types A and B from North America. |
| AID419571 | Antibacterial activity against Escherichia coli MTCC 51 at 100 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID1456568 | Antibacterial activity against Streptococcus mutans MTCC 890 after 24 hrs by broth microdilution method | |||
| AID1168609 | Antibacterial activity against Klebsiella pneumoniae at 50 ug/mL incubated for 24 hrs by agar well diffusion method | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets. |
| AID289147 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines. |
| AID460794 | Antibacterial activity against Staphylococcus aureus ATCC 29213 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID1156690 | Antimicrobial activity against Klebsiella pneumonia MTCC 109 assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID1255672 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 assessed as growth inhibition at 100 ug/ml after 8 to 24 hrs by agar well diffusion method | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID370254 | Antimycobacterial activity against Mycobacterium tuberculosis Kurono infected ICR mouse assessed as viable lung bacterial count at 20 mg/kg, po administered once daily measured after 28 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID1435652 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 234/2005 after 14 days by micromethod | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. |
| AID625281 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1596680 | Antibacterial activity against Salmonella typhimurium ATCC 13311 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID490978 | Antifungal activity against Aspergillus niger NCIM 545 after 48 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach. |
| AID535771 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H carrying the luxAB gene under the hsp60 promoter agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID381884 | Antimicrobial activity against Staphylococcus epidermidis ATCC 12228 by serial dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | A novel sesquiterpene lactone from Centaurea pullata: structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties. |
| AID200348 | Antibacterial activity was evaluated against salmonella. | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID67877 | Antibacterial activity against gram negative bacteria Enterobacter aerogens was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID537115 | Protection index, ratio of CC50 for Mycobacterium tuberculosis infected mouse J774A1 cells to MIC for Mycobacterium tuberculosis H37Rv ATCC 27294 | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22 | Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin. |
| AID631059 | Antimicrobial activity against Yersinia pestis KIM6-2082.1+ in PMHD medium supplemented with 100 uM FeCl3 after 26 hrs by spectrophotometric analysis | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID594332 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID719318 | Antimicrobial activity against Staphylococcus aureus NCIM 5021 at 10 ug/disc incubated for 24 hrs by agar disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID396000 | Antimicrobial activity against Mycoplasma putrefaciens French isolates after 24 hrs by twofold serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. |
| AID545532 | Antibacterial activity against Salmonella typhi ATCC 24915 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide. |
| AID1171265 | Inhibition of YopH in Yersinia pseudotuberculosis YPIII PIB102-Elux using p-nitrophenyl phosphate as substrate measured after 3 hrs 15 mins by phosphatase enzyme assay | 2014 | Journal of natural products, Dec-26, Volume: 77, Issue:12 | Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems. |
| AID448071 | Antibacterial activity against Erwinia aroideae at 50 mg/L after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Design, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)quinoline-3-carboxylic acid derivatives. |
| AID374113 | Antimicrobial activity against azide-resistant Escherichia coli J53 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID521802 | Antimicrobial activity against Francisella tularensis subsp. tularensis after 48 hrs by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Jun, Volume: 52, Issue:6 | In vitro susceptibility of isolates of Francisella tularensis types A and B from North America. |
| AID1125797 | Antifungal activity against Saccharomyces cerevisiae NCIM 3044 assessed as diameter of growth inhibition zone at 10 ug/ml after 4 days by agar disc diffusion method | 2014 | European journal of medicinal chemistry, Apr-22, Volume: 77 | New polyfunctional imidazo[4,5-C]pyridine motifs: synthesis, crystal studies, docking studies and antimicrobial evaluation. |
| AID456354 | Antibacterial activity against Bacillus cereus NCIB 6349 after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID278538 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium breve R0070 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1143263 | Antimycobacterial activity against Mycobacterium tuberculosis Beijing (E-47/94) assessed as growth inhibition after 2 to 3 weeks by turbidometry | 2014 | Journal of medicinal chemistry, Jun-12, Volume: 57, Issue:11 | Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. |
| AID490981 | Antifungal activity against Candida albicans MTCC 277 after 24 to 72 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach. |
| AID289152 | Antimycobacterial activity against streptomycin, isoniazid, ethambutol-resistant Mycobacterium tuberculosis CIBIN 112 isolates | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines. |
| AID275055 | Antibacterial activity against Escherichia coli pTMV19 | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25 | Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin. |
| AID565749 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID381887 | Antimicrobial activity against Salmonella enteritidis ATCC 13076 by serial dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | A novel sesquiterpene lactone from Centaurea pullata: structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties. |
| AID442402 | Antimicrobial activity against Staphylococcus aureus at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID320706 | Inhibition of PAD4 by ABPP-based assay | 2008 | Bioorganic & medicinal chemistry, Jan-15, Volume: 16, Issue:2 | Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors. |
| AID326550 | Antimicrobial activity against Mycobacterium abscessus V120 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID341100 | Protein binding in human serum at 1 g, iv | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID1247101 | Antibacterial activity against Enterobacter aerogenes assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID1272620 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 21 days by broth microdilution method | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. |
| AID678659 | Antibacterial activity against Bacillus proteus by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of novel N-acyl substituted quinolin-2(1H)-one derivatives as potential antimicrobial agents. |
| AID625279 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID600682 | Bactericidal activity against Listeria monocytogenes NCTC 7973 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID544021 | Antimicrobial activity against Psychrobacter sp. DY9-2 isolate C711 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID442401 | Antimicrobial activity against Micrococcus flavus at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1435650 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 131 after 14 days by micromethod | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. |
| AID358877 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 35818 at 1 ug/disk by disk diffusion susceptibility assay | 2001 | Journal of natural products, Mar, Volume: 64, Issue:3 | Pitipeptolides A and B, new cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. |
| AID594331 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID733704 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 after 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID442405 | Antimicrobial activity against Enterobacter cloacae at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID544028 | Antimicrobial activity against Acinetobacter lwoffii isolate C141 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1546157 | Antifungal activity against Candida albicans assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID375850 | Antibacterial activity against Klebsiella pneumoniae after 48 hrs by agar well diffusion method | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13 | Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes. |
| AID509469 | Antibacterial activity against Bacillus subtilis at 50 ug/mL | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID442424 | Antimicrobial activity against Bacillus cereus after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1091746 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 assessed as inhibition zones at 100 ug/disk at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID1174110 | Antimycobacterial activity against isoniazid, rifampin, streptomycin-resistant Mycobacterium tuberculosis after 7 days by microplate Alamar blue assay | 2015 | European journal of medicinal chemistry, Jan-07, Volume: 89 | Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis. |
| AID637082 | Antibacterial activity against Acinetobacter johnsonii ATCC 17909 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID376317 | Antibacterial activity against Agrobacterium tumefaciens A281 after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID1596668 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hrs by iodonitrotetrazolium chloride dye based microdilution assay | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID332793 | Antibacterial activity against Klebsiella pneumoniae at 10 mg/10 ml dimethylformamide | |||
| AID696346 | Antibacterial activity against Escherichia coli ATCC 26032 after 24 hrs by two fold serial dilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 22, Issue:21 | Design, synthesis, spectral and biological evaluation of novel 1-allyl substituted 2,6-diphenylpiperidin-4-ones and its derivatives of oximes/oxime ethers. |
| AID419576 | Antibacterial activity against Bacillus stearothermophilus MTCC 8508 after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID1616519 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by broth microdilution method | 2019 | Journal of natural products, 10-25, Volume: 82, Issue:10 | Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from |
| AID1545437 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as diameter of zone inhibition at 30 ug/ml | 2019 | Bioorganic & medicinal chemistry, 04-01, Volume: 27, Issue:7 | Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances. |
| AID1304838 | Antibacterial activity against Mycobacterium tuberculosis H37Ra ATCC 25177 after 7 days by two-fold serial dilution method | 2016 | Journal of medicinal chemistry, 04-28, Volume: 59, Issue:8 | Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis. |
| AID544281 | Antimicrobial activity against Enterococcus faecalis NKH11 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID373987 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr deficient Escherichia coli J53 qnrA1 bearing pHS4 transconjugant from Enterobacter cloacae 91 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID673187 | Antimicrobial activity against Escherichia coli MTCC 1650 after 24 hrs by agar well diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 22, Issue:15 | Synthesis and biological evaluation of novel 2,4,6-triazine derivatives as antimicrobial agents. |
| AID584115 | Antibacterial activity against Escherichia coli KAM32 harboring pSP72 by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus. |
| AID532984 | Antibacterial activity against Escherichia coli MG1655 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID278558 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium animalis ATCC 27536 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1179569 | Antibacterial activity against methicillin-resistant Staphylococcus aureus at 100 ug/well after 24 hrs by well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives. |
| AID540930 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor 92G harboring rpsL gene with inserted glycine at position 92 after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID1091748 | Antibacterial activity against Lysinibacillus sphaericus MTCC 11 assessed as inhibition zones at 100 ug/disk at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID332788 | Antibacterial activity against Vibrio cholerae at 10 mg/10 ml dimethylformamide | |||
| AID569255 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID574794 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 2911 obtained from sputum of patient at 1 ug/ml by Bactec MGIT960 modified proportion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID1170142 | Antimicrobial activity against Staphylococcus aureus subsp. aureus DSM 799 incubated for 24 hrs by disk diffusion method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Antibacterial secondary metabolites from an endophytic fungus, Eupenicillium sp. LG41. |
| AID424605 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH362 (SCV-34) harboring TAA stop codon at nucleotide 282 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID737330 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 at 750 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID1233486 | Antimicrobial activity against Shigella flexneri MTCC 1457 assessed as inhibition of visual microbial growth incubated for 24 hrs at 37 degC | 2015 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 25, Issue:14 | Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. |
| AID1156892 | Antimicrobial activity against Aspergillus clavatus MTCC 1323 after 24 hrs by NCCLS M7-A5 method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID601249 | Antibacterial activity against Escherichia coli assessed as 99.5% bacterial killing using 1 x 10'4 CFU/ml inoculum after 72 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID530236 | Resistance factor, ratio of MIC for Mycobacterium bovis BCG ML1034 to MIC for wild-type Mycobacterium bovis BCG | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID625529 | Antimicrobial activity against Escherichia coli MTCC 443 by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Iodine-catalyzed conjugate addition of indoles onto en-1,4-dione: a novel synthesis of 3-(1-(1H-indol-3-yl)-2-oxo-2-phenylethyl)indolin-2-ones as antibacterial and antifungal agents. |
| AID294963 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID1247073 | Antibacterial activity against Staphylococcus aureus assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID565994 | Antimycobacterial activity against Mycobacterium tuberculosis H37Ra by twofold agar dilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and anti-mycobacterial activities of triazoloquinolones. |
| AID644170 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID719315 | Antimicrobial activity against Bacillus subtilis NCIM 2999 by broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID1544787 | Antimicrobial activity against Pseudomonas aeruginosa assessed as zone of inhibition at 10 ug/disk after 24 hrs by disk diffusion method | 2019 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 29, Issue:13 | Synthesis and biological evaluation of 2-chloro-3-[(thiazol-2-yl)amino]-1,4-naphthoquinones. |
| AID561107 | Antibacterial activity against Pasteurella multocida BB1041 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID585418 | Antimicrobial activity against Escherichia coli C600 by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID539693 | Antifungal activity against Escherichia coli MTCC 443 by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Indium(III) chloride catalyzed three-component coupling reaction: a novel synthesis of 2-substituted aryl(indolyl)kojic acid derivatives as potent antifungal and antibacterial agents. |
| AID534827 | Antimicrobial activity against Campylobacter fetus subsp. fetus CA75 harboring pCA75 carrying ant(6)-Ib resistant gene of 1516477 in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID375851 | Antibacterial activity against Escherichia coli after 48 hrs by agar well diffusion method | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13 | Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes. |
| AID268913 | Antibacterial activity against Mycobacterium smegmatis | 2006 | Journal of medicinal chemistry, Aug-10, Volume: 49, Issue:16 | Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity. |
| AID1104308 | Antibacterial activity against Listeria monocytogenes NCTC 7973 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID419826 | Antibacterial activity against Bacillus subtilis MTCC 619 at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID419574 | Antibacterial activity against Pseudomonas putida MTCC 121 at 100 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID545531 | Antibacterial activity against Bacillus subtilis ATCC 451 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide. |
| AID1443995 | Hepatotoxicity in human assessed as drug-induced liver injury | 2014 | Hepatology (Baltimore, Md.), Sep, Volume: 60, Issue:3 | Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. |
| AID1546648 | Antibacterial activity against Bacillus subtilis MTCC 441 assessed as reduction in microbial growth after 24 hrs by CLSI based microdilution method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID565750 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID445329 | Cytotoxicity against human THP1 cells | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID601173 | Antibacterial activity against Pseudomonas aeruginosa using 1 x 10'4 CFU/ml inoculum after 24 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID341102 | Free Cmin in human at 1 g, iv | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID424588 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH348 (SCV-20) harboring TGA stop codon at nucleotide 244 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID424593 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH379 (SCV-51) harboring TAA stop codon at nucleotide 418 in rplF but gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1105403 | Antibacterial activity against Klebsiella pneumoniae MTCC 7028 assessed as growth inhibition after 24 hr by broth dilution method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID1596674 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID321431 | Antibacterial activity against Salmonella enteritidis ATCC 13076 after 24 hrs by microdilution test | 2008 | Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3 | Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1201579 | Antibacterial activity against Pseudomonas aeruginosa at 0.5 mg/ml incubated for 18 hrs by well plate technique | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. |
| AID245345 | Minimum inhibitory concentration against gram negative Chromobacterium violaceum (MTCC 2656) using broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17 | Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents. |
| AID311789 | Antibacterial activity against Salmonella enteritidis by microdilution technique | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | Minor sesquiterpene lactones from Centaurea pullata and their antimicrobial activity. |
| AID1179269 | Antimicrobial activity against Klebsiella pneumoniae MTCC 109 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID311350 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs by MTT assay | 2007 | Journal of natural products, Sep, Volume: 70, Issue:9 | Targeted natural product isolation guided by HPLC-SPE-NMR: constituents of Hubertia species. |
| AID648391 | Antibacterial activity against Salmonella paratyphi B at 10 ug/disc after 24 hrs by disc diffusion assay | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID424829 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH420 harboring deletion of nucleotide 72-80 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID424340 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH201 harboring Gly452Cys mutation in fusA after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID723716 | Bactericidal activity against Bacillus cereus clinical isolate after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID424343 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH206 harboring Arg464Ser mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1247092 | Antibacterial activity against Proteus vulgaris after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID539692 | Antifungal activity against Staphylococcus epidermidis MTCC 2639 by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Indium(III) chloride catalyzed three-component coupling reaction: a novel synthesis of 2-substituted aryl(indolyl)kojic acid derivatives as potent antifungal and antibacterial agents. |
| AID619773 | Antibacterial activity against Pseudomonas aeruginosa RCMB 000102 at 30 mg/ml after 24 hrs by agar well diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Design and synthesis of some new thiophene, thienopyrimidine and thienothiadiazine derivatives of antipyrine as potential antimicrobial agents. |
| AID633947 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID419578 | Antibacterial activity against Pseudomonas putida MTCC 121 after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID601175 | Antibacterial activity against Bacillus cereus assessed as 99.5% bacterial killing using 1 x 10'4 CFU/ml inoculum after 72 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID424598 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH337 (SCV-9) harboring -1 frameshift mutation at nucleotide 220 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1443991 | Induction of mitochondrial dysfunction in Sprague-Dawley rat liver mitochondria assessed as inhibition of mitochondrial respiration per mg mitochondrial protein measured for 20 mins by A65N-1 oxygen probe based fluorescence assay | 2014 | Hepatology (Baltimore, Md.), Sep, Volume: 60, Issue:3 | Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. |
| AID541817 | Antibacterial activity against wild-type Bacillus subtilis 168 after 15 hrs | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Inactivation of KsgA, a 16S rRNA methyltransferase, causes vigorous emergence of mutants with high-level kasugamycin resistance. |
| AID631058 | Antimicrobial activity against Yersinia pestis KIM6-2082.1+ in PMHD medium after 26 hrs by spectrophotometric analysis | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID1143266 | Antimycobacterial activity against streptomycin-resistant Mycobacterium tuberculosis 136570 assessed as growth inhibition after 2 to 3 weeks by turbidometry | 2014 | Journal of medicinal chemistry, Jun-12, Volume: 57, Issue:11 | Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. |
| AID562381 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1183530 | Antibacterial activity against Escherichia coli MTCC-725 assessed as zone of inhibition at 10 ug/disc | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties. |
| AID1286942 | Antibacterial activity against Proteus vulgaris MTCC 1771 by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 26, Issue:6 | Indole-2-carboxylic acid derived mono and bis 1,4-disubstituted 1,2,3-triazoles: Synthesis, characterization and evaluation of anticancer, antibacterial, and DNA-cleavage activities. |
| AID633853 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID424425 | Antibacterial activity against Enterococcus faecalis AIS2007003 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID585425 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G375-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1091742 | Antibacterial activity against Lysinibacillus sphaericus MTCC 11 assessed as growth arrest at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID535772 | Antimicrobial activity against Mycobacterium ulcerans 1059 agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID1247079 | Antibacterial activity against Micrococcus luteus assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID544010 | Antimicrobial activity against Enterococcus hirae isolate PGS48 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID404095 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 by microdilution method | 2005 | Journal of natural products, Sep, Volume: 68, Issue:9 | Sesquiterpene lactones from Centaurea spinosa and their antibacterial and cytotoxic activities. |
| AID490977 | Antifungal activity against Candida albicans MTCC 277 after 48 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach. |
| AID408877 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID424586 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH352 (SCV-24) harboring -1 frameshift mutation at nucleotide 106 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1061252 | Antimicrobial activity against Escherichia coli at 1 mg/ml by well plate method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Synthesis and biological evaluation of novel substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1-b] [1,3,4] thiadiazole derivatives. |
| AID575169 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 1000 uM by spectrofluorometric assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID737338 | Antimicrobial activity against Escherichia coli MTCC 723 at 500 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID1186777 | Antibacterial activity against Streptococcus pyogenes MTCC 1926 at 30 ug/ml after 24 hrs by agar well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17 | Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: synthesis, characterization and evaluation of anticancer and antimicrobial activities. |
| AID649473 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 6 days by MTT assay | 2012 | Bioorganic & medicinal chemistry, Mar-15, Volume: 20, Issue:6 | Anti-mycobacterial activities of some cationic and anionic calix[4]arene derivatives. |
| AID535775 | Antimicrobial activity against Mycobacterium ulcerans 1059 harboring pTY60K containing pMH94 carrying the luxAB gene under the hsp60 promoter after 14 days determined according to RLU count by real-time luminescence method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID341093 | Antimicrobial activity against antibiotic-resistant Yersinia pestis mutant on day 4 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID1174108 | Antimycobacterial activity against isoniazid, rifampin, ethambutol, ofloxacin-resistant Mycobacterium tuberculosis after 7 days by microplate Alamar blue assay | 2015 | European journal of medicinal chemistry, Jan-07, Volume: 89 | Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis. |
| AID278521 | Antimicrobial activity against Bifidobacterium animalis ATCC 27536 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID424833 | Ratio of MIC for kanamycin-resistant Staphylococcus aureus harboring mutations in FusA gene to MIC for wild type kanamycin-susceptible Staphylococcus aureus AH001 | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID143714 | In vitro antibacterial activity against Mycobacterium avium 103317 | 1999 | Bioorganic & medicinal chemistry letters, Oct-18, Volume: 9, Issue:20 | New pyrrole derivatives as antimycobacterial agents analogs of BM212. |
| AID448072 | Antibacterial activity against Bacillus subtilis at 50 mg/L after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Design, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)quinoline-3-carboxylic acid derivatives. |
| AID69822 | Tested for the antimicrobial activity as minimum inhibitory concentration against Escherichia coli ATCC 25922 | 2002 | Bioorganic & medicinal chemistry letters, Mar-11, Volume: 12, Issue:5 | New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation. |
| AID278859 | Inhibition of metabolic activity in MG63 cells assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID544058 | Antimicrobial activity against Shigella flexneri isolate C506 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1224527 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 131 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID515235 | Antibacterial activity against Escherichia coli at 50 ug/ml after 18 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Anti-tubercular agents. Part 5: synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners. |
| AID311790 | Antibacterial activity against Escherichia coli ATCC 35210 by microdilution technique | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | Minor sesquiterpene lactones from Centaurea pullata and their antimicrobial activity. |
| AID1179271 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus MTCC 96 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID1055964 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolate X004244 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1272600 | Antibacterial activity against Staphylococcus aureus MTCC 96 after 24 hrs by broth microdilution technique | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. |
| AID244855 | Minimum inhibitory concentration against Staphylococcus aureus | 2005 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 15, Issue:7 | Enhancement in antimicrobial activity of 2-(phenyl)-3-(2-butyl-4-chloro-1H-imidazolyl)-5-butylate isoxazolidine. |
| AID534825 | Antimicrobial activity against Campylobacter fetus subsp. fetus CA73 harboring pCA73 carrying tet(44) resistance gene of 1516477 in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID674378 | Antibacterial activity Escherichia coli ATCC 25922 at 1 mg/ml after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: as a new class of potent antioxidants and antimicrobials--a novel accost to amend biocompatibility. |
| AID495753 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow and treated with Cefixime-cluvulanic acid by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID1143269 | Antimycobacterial activity against ethambutol-resistant Mycobacterium tuberculosis 17003 assessed as growth inhibition after 2 to 3 weeks by turbidometry | 2014 | Journal of medicinal chemistry, Jun-12, Volume: 57, Issue:11 | Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. |
| AID530252 | Antimicrobial activity against dnaK deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 10 ug/ml after 3 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID279863 | Antimicrobial activity against Burkholderia pseudomallei KHW | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID544282 | Antimicrobial activity against Enterococcus faecalis NKH12 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID673188 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 after 24 hrs by agar well diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 22, Issue:15 | Synthesis and biological evaluation of novel 2,4,6-triazine derivatives as antimicrobial agents. |
| AID1179286 | Antimicrobial activity against Shigella flexneri MTCC 1457 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID1247083 | Antibacterial activity against Pseudomonas aeruginosa assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID1476350 | Antitubercular activity against isoniazid resistant Mycobacterium tuberculosis H37Rv ATCC 35822 after 24 hrs by MABA method | 2017 | Journal of medicinal chemistry, 10-26, Volume: 60, Issue:20 | Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity. |
| AID620347 | Antibacterial activity against Bacillus subtilis RCMB 000107 at 30 ug/ml after 24 hrs by diffusion agar technique | 2011 | European journal of medicinal chemistry, Oct, Volume: 46, Issue:10 | Synthesis and anti-microbial activity of some 1- substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives. |
| AID66760 | Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID370070 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 35838 after 14 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID404895 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB10 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID509480 | Antibacterial activity against Bacillus subtilis | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID540932 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor SP2 harboring rpsL K88E mutant gene and inserted glycine at position 92 of the gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID585424 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G062-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID515919 | Antibacterial activity against streptomycin-resistant Mycobacterium tuberculosis after 7 days by microplate alamar blue assay | 2010 | Bioorganic & medicinal chemistry, Oct-15, Volume: 18, Issue:20 | Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring. |
| AID1647343 | Antibacterial activity against Pseudomonas aeruginosa by dilution assay | 2020 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2 | The bioisosteric modification of pyrazinamide derivatives led to potent antitubercular agents: Synthesis via click approach and molecular docking of pyrazine-1,2,3-triazoles. |
| AID278531 | Antimicrobial activity against Bifidobacterium pseudolongum ATCC 25562 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID453949 | Antitubercular activity against Mycobacterium tuberculosis H37Rv by BACTEC460 radiometric susceptibility assay | 2010 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 20, Issue:2 | Antitubercular potential of some semisynthetic analogues of phytol. |
| AID600684 | Bactericidal activity against Salmonella Typhimurium ATCC 13311 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID277995 | Antibacterial activity against Escherichia coli ESS K12 | 2007 | Journal of natural products, Feb, Volume: 70, Issue:2 | Antimicrobial ambiguines from the cyanobacterium Fischerella sp. collected in Israel. |
| AID537116 | Antimycobacterial activity against rifampin-resistant Mycobacterium tuberculosis after 3 to 28 days by twofold dilution method | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22 | Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin. |
| AID424579 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH340 (SCV-12) harboring Gly617Asp mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1596677 | Bactericidal activity against Enterobacter cloacae incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID563503 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 79 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID332798 | Antibacterial activity against Salmonella Typhimurium at 10 mg/10 ml dimethylformamide | |||
| AID1183532 | Antibacterial activity against Aeromonas hydrophila MTCC-1739 assessed as zone of inhibition at 10 ug/disc | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties. |
| AID1156679 | Antimicrobial activity against Klebsiella pneumonia MTCC 109 assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID1091740 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 assessed as growth arrest at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID283642 | Decrease in sensitivity of Escherichia coli K12 MG1655 assessed as reduction in zone of inhibition in presence of 10 mM glutathione by disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID637031 | Antibacterial activity against Sarcina lutea ATCC 9341 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID588220 | Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset | 2008 | Toxicology mechanisms and methods, , Volume: 18, Issue:2-3 | Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. |
| AID569259 | Antimycobacterial activity against Mycobacterium avium subsp. avium ATCC 2529I | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID572151 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBADomegaydhE plasmid containing Escherichia coli multidrug efflux pump YdhE after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID594339 | Antimicrobial activity against Proteus vulgaris NCIM 2027/ATCC 13315 at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID65066 | Percent killing of the total Escherichia coli K12 (ATCC 25868)cells at the C50 concentration was determined. | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID1061247 | Antimicrobial activity against Pseudomonas aeruginosa at 0.5 mg/ml by well plate method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Synthesis and biological evaluation of novel substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1-b] [1,3,4] thiadiazole derivatives. |
| AID633949 | Antibacterial activity against Enterococcus faecalis isolated from human incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID278560 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium bifidum BB12 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID562588 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID279872 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 3.9 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID644171 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID92475 | Inhibitory activity of the aminoglycoside on Staphylococcus aureus IF-2 binding to fMet-tRNA(fMet) | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6 | Inhibition of bacterial IF2 binding to fMet-tRNA((fMet)) by aminoglycosides. |
| AID515324 | Antibacterial activity against Pseudomonas aeruginosa at 100 ug/ml after 24 to 48 hrs by cup-plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Synthesis and biological property of some novel 1,3,4-oxadiazoles. |
| AID442412 | Antimicrobial activity against Pseudomonas aeruginosa at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID594336 | Antimicrobial activity against Escherichia coli NCIM 2068/ATCC 11105 at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID637021 | Antibacterial activity against Escherichia coli ATCC 8739 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID448317 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 by broth dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, photochemical E (trans)-->Z (cis) isomerization and antimicrobial activity of 2-chloro-5-methylpyridine-3-olefin derivatives. |
| AID1245989 | Antimicrobial activity against streptomycin-resistant Erwinia amylovora after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID358864 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 25177 at 25 ug/disk by disk diffusion susceptibility assay | 2001 | Journal of natural products, Mar, Volume: 64, Issue:3 | Pitipeptolides A and B, new cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. |
| AID445289 | Antibacterial activity against Staphylococcus aureus by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID643383 | Induction of phospholipidosis in bovine corneal fibroblasts assessed as lamellar inclusion bodies after 72 hrs by light microscopy | 2012 | Journal of medicinal chemistry, Jan-12, Volume: 55, Issue:1 | In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. |
| AID206362 | Compound (isolated from leaves of Cistus monspeliensis) was tested for antimicrobial activity against Staphylococcus epidermidis (ATCC 12228) | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | A simple and rapid method for the differentiation of C-13 manoyl oxide epimers in biologically important samples using GC-MS analysis supported with NMR spectroscopy and computational chemistry results. |
| AID588209 | Literature-mined public compounds from Greene et al multi-species hepatotoxicity modelling dataset | 2010 | Chemical research in toxicology, Jul-19, Volume: 23, Issue:7 | Developing structure-activity relationships for the prediction of hepatotoxicity. |
| AID535776 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60K containing pMH94 carrying the luxAB gene under the hsp60 promoter after 7 days determined according to RLU count by real-time luminescence method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID1303883 | Antibacterial activity against methicillin resistant Staphylococcus aureus subsp. aureus HPV107 (ATCC BAA-44) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID1075581 | Antimicrobial activity against Listeria monocytogenes ATCC 7644 after 18 to 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents. |
| AID1255667 | Antibacterial activity against Staphylococcus aureus ATCC 6538P assessed as growth inhibition at 25 ug/ml after 8 to 24 hrs by agar well diffusion method | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID424344 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH190 harboring Arg464His mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID220347 | Percent of interaction with calf thymus DNA (activated type XV) at a concentration of 35 uM | 2001 | Bioorganic & medicinal chemistry letters, Apr-23, Volume: 11, Issue:8 | Study of aminoglycoside-nucleic acid interactions by an HPLC method. |
| AID648378 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 after 24 hrs by twofold serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID530050 | Antimicrobial activity against Staphylococcus aureus 286607-R1 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID561112 | Antibacterial activity against Pasteurella multocida BB1046 harboring plasmid pB1003 bearing blaROB-1 gene and plasmid pB1002 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID615479 | Antimicrobial activity against Pseudomonas aeruginosa at 50 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID374112 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr expressing Escherichia coli J53 qnrA1 bearing pHS6 transconjugant from Escherichia coli 650 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID442419 | Antimicrobial activity against Escherichia coli at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID408879 | Antimycobacterial activity against Mycobacterium marinum CIP 6423 | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID283650 | Antibacterial activity against Escherichia coli K12 XL1 Blue | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID1463960 | Antimycobacterial activity MDR/XDR against Mycobacterium tuberculosis isolate 234/2005 incubated for 14 days by micromethod | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents. |
| AID537113 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 3 to 28 days by twofold dilution method | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22 | Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin. |
| AID775853 | Antitubercular activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition by micro plate alamar blue assay | 2013 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 23, Issue:21 | Studies on substituted benzo[h]quinazolines, benzo[g]indazoles, pyrazoles, 2,6-diarylpyridines as anti-tubercular agents. |
| AID562587 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID666778 | Antibacterial activity against Escherichia coli at 0.05 mg by agar diffusion test | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13 | Bioactive briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. |
| AID279880 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 7.8 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID678626 | Antibacterial activity against Escherichia coli ATCC 3509 at 50 mg/ml after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of optically active conjugated γ- and δ-lactone derivatives. |
| AID774300 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 by microplate Alamar blue assay | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID301999 | Cytotoxicity against Vero cells after 48 hrs by XTT method | 2007 | Bioorganic & medicinal chemistry, Dec-15, Volume: 15, Issue:24 | Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase. |
| AID714932 | Antimicrobial activity against Aspergillus flavus NCIM 524 at 100 ug/mL incubated for 48 hrs by agar disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID733709 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 1 mg/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID1454340 | Antibacterial activity Bacillus subtilis MTCC 441 by agar well method | 2017 | Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15 | Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides. |
| AID540209 | Volume of distribution at steady state in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID544029 | Antimicrobial activity against Bacillus psychrodurans isolate C328 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID341103 | Half life in human plasma at 1 g, iv | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID574788 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 2301 obtained from sputum of patient at 1 ug/ml by Bactec MGIT960 modified proportion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID600723 | Antibacterial activity against Bacillus subtilis at 10 ug/disc after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Urea/thiourea derivatives of quinazolinone-lysine conjugates: synthesis and structure-activity relationships of a new series of antimicrobials. |
| AID574809 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 2474 horboring rpoB H526Y, katG D329A/R463L, gyrA D94G/S95T, rrs A1401G by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID1241213 | Ratio of Kd for 5'-FAM-pre-miR-372 (unknown origin) in presence of 100-fold excess of Escherichia coli tRNA to Kd for 5'-FAM-pre-miR-372 (unknown origin) | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID648385 | Antibacterial activity against methicillin-resistant Staphylococcus aureus at 10 ug/disc after 24 hrs by disc diffusion assay | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID1156692 | Antimicrobial activity against Shigella flexneri MTCC 1457 assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID509468 | Antibacterial activity against Escherichia coli at 100 ug/mL | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID770973 | Antibacterial activity against Staphylococcus aureus MTCC 96 by broth dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Demonic axe-like conjugated alkynes in combating microbes. |
| AID456438 | Antibacterial activity against Klebsiella pneumoniae NCIB 418 after 72 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID633855 | Antibacterial activity against Enterococcus faecalis isolated from human after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID725543 | Potentiation of streptomycin antimicrobial activity against methicillin-resistant Staphylococcus aureus at 10 ug/ml after 20 hrs by liquid microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3 | Discovery of nosokophic acid, a predicted intermediate of moenomycins, from nosokomycin-producing Streptomyces sp. K04-0144. |
| AID1104310 | Antibacterial activity against Salmonella enterica subsp. enterica serovar TyphimuriumATCC 13311 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID294760 | Antibacterial activity against Mycobacterium avium 724S after 2 weeks by broth dilution method | 2007 | Bioorganic & medicinal chemistry letters, May-01, Volume: 17, Issue:9 | Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus. |
| AID1463962 | Antimycobacterial activity MDR/XDR against Mycobacterium tuberculosis isolate 8666/2010 incubated for 14 days by micromethod | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents. |
| AID278540 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium longum ATCC 15707 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID382575 | Antibacterial activity against Escherichia coli assessed as diameter of inhibition zone at 0.5% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID456434 | Antibacterial activity against Bacillus subtilis NCIB 3610 after 72 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID1255671 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 assessed as growth inhibition at 25 ug/ml after 8 to 24 hrs by agar well diffusion method | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID355890 | Antimicrobial activity against Micrococcus flavus ATCC 10240 after 36 hrs under aerobic condition by microdilution method | 2003 | Journal of natural products, May, Volume: 66, Issue:5 | Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity. |
| AID1456567 | Antibacterial activity against Clostridium sporogenes NICM 2559 after 24 hrs by broth microdilution method | |||
| AID694231 | Antibacterial activity against Mycobacterium tuberculosis H37Rv under anaerobic condition by BACTEC method | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. |
| AID1054722 | Antibacterial activity against Bacillus cereus Frankland and Frankland ATCC 11778 after overnight incubation by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 | Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley. |
| AID1247078 | Antibacterial activity against Proteus vulgaris assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID381883 | Antimicrobial activity against Micrococcus flavus ATCC 10240 by serial dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | A novel sesquiterpene lactone from Centaurea pullata: structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties. |
| AID674380 | Antibacterial activity Pseudomonas aeruginosa ATCC 27853 at 1 mg/ml after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: as a new class of potent antioxidants and antimicrobials--a novel accost to amend biocompatibility. |
| AID509479 | Antibacterial activity against Escherichia coli | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID600677 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1546166 | Antimicrobial activity against Pseudomonas aeruginosa assessed as zone of inhibition at 5 mg/ml after 24 to 48 hrs by well diffusion method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID747757 | Antibacterial activity against Pseudomonas aeruginosa | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID1143267 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis 912253 assessed as growth inhibition after 2 to 3 weeks by turbidometry | 2014 | Journal of medicinal chemistry, Jun-12, Volume: 57, Issue:11 | Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. |
| AID279874 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 500 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID615478 | Antimicrobial activity against Pseudomonas aeruginosa at 25 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID532021 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H containing pCK0601 carrying the luxAB gene under the hsp60 promoter after 14 days determined according to CFU counts by bioluminescence method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID460793 | Antibacterial activity against methicillin-resistant Staphylococcus aureus BAA-44 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID279877 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 62.5 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID1253866 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis FJ05120 after 3 to 4 weeks by microplate alamar blue assay | 2015 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 25, Issue:22 | Discovery of the disubstituted oxazole analogues as a novel class anti-tuberculotic agents against MDR- and XDR-MTB. |
| AID278861 | Inhibition of metabolic activity in HeLa cells assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID424337 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH194 harboring Pro404Leu mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1079942 | Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source] | |||
| AID293413 | Antibacterial activity against Klebsiella pneumoniae by disc diffusion method | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis of some new bioactive 3-amino-2-mercapto-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one derivatives. |
| AID1204387 | Antibacterial activity against Bacillus subtilis assessed as growth inhibition at 100 umol/L after 8 hrs by ELISA plate reader analysis relative to control | 2015 | European journal of medicinal chemistry, Jun-05, Volume: 97 | Benzaldehyde Schiff bases regulation to the metabolism, hemolysis, and virulence genes expression in vitro and their structure-microbicidal activity relationship. |
| AID1653413 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv by BACTEC radiometric growth assay | 2019 | Bioorganic & medicinal chemistry, 07-01, Volume: 27, Issue:13 | Insights of synthetic analogues of anti-leprosy agents. |
| AID477409 | Antibacterial activity against Staphylococcus aureus NCTC 8325 after 16 to 20 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID636966 | Antibacterial activity against Bacillus cereus ATCC 11778 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID656229 | Antimycobacterial activity against isoniazid-, rifampin-, streptomycin-resistant Mycobacterium tuberculosis after 16 to 24 hrs by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. |
| AID656228 | Antimycobacterial activity against isoniazid-, rifampin-, ethambutol-resistant Mycobacterium tuberculosis after 16 to 24 hrs by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. |
| AID1055957 | Antimycobacterial activity against kanamycin-resistant Mycobacterium tuberculosis ATCC 35827 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID278563 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium longum ATCC 15707 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID665397 | Antibacterial activity against Escherichia coli MTCC 42 after 24 hrs by serial dilution technique | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Synthesis, characterization, antimicrobial activities and QSAR studies of some 10a-phenylbenzo[b]indeno[1,2-e][1,4]thiazin-11(10aH)-ones. |
| AID218066 | In vitro cytotoxicity against vero cells | 1999 | Bioorganic & medicinal chemistry letters, Oct-18, Volume: 9, Issue:20 | New pyrrole derivatives as antimycobacterial agents analogs of BM212. |
| AID278523 | Antimicrobial activity against Bifidobacterium bifidum ATCC 15696 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID588213 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID715626 | Antibacterial activity against Escherichia coli MTCC 42 after 24 hrs by serial dilution method | 2012 | European journal of medicinal chemistry, Nov, Volume: 57 | Synthesis, characterization, biological evaluation and QSAR studies of 11-p-substituted phenyl-12-phenyl-11a,12-dihydro-11H-indeno[2,1-c][1,5]benzothiazepines as potential antimicrobial agents. |
| AID1156883 | Antimicrobial activity against Candida albicans MTCC 277 at 100 ug/disc after 48 hrs by agar cup plate method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID320035 | Antibacterial activity against Staphylococcus epidermidis by broth dilution method | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3 | Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates. |
| AID381885 | Antimicrobial activity against Escherichia coli ATCC 35210 by serial dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | A novel sesquiterpene lactone from Centaurea pullata: structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties. |
| AID532983 | Antibacterial activity against Escherichia coli W3110 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID567091 | Drug absorption in human assessed as human intestinal absorption rate | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Prediction of drug intestinal absorption by new linear and non-linear QSPR. |
| AID1555492 | Antimycobacterial activity against Staphylococcus aureus FDA 209P by agar diffusion method | 2019 | European journal of medicinal chemistry, Aug-15, Volume: 176 | Salinomycin and its derivatives - A new class of multiple-targeted "magic bullets". |
| AID268912 | Antibacterial activity against Mycobacterium marinum | 2006 | Journal of medicinal chemistry, Aug-10, Volume: 49, Issue:16 | Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity. |
| AID445332 | Selectivity for Mycobacterium tuberculosis H37Rv over human THP1 cells | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID770971 | Antibacterial activity against Escherichia coli MTCC 443 by broth dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Demonic axe-like conjugated alkynes in combating microbes. |
| AID587763 | Antimicrobial activity against recombinant Mycobacterium ulcerans Mu1059 expressing luxAB from vibrio harveyi infected BALB/c mouse assessed as reduction in foodpad relative light unit after 2 weeks relative to basal level | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Using bioluminescence to monitor treatment response in real time in mice with Mycobacterium ulcerans infection. |
| AID289148 | Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis CIBIN 687 isolates | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines. |
| AID626288 | Antibacterial activity against Escherichia coli ATCC 25922 at 0.25 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID279905 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 3.9 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID1156675 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID144021 | Antimycobacterial activity against Mycobacterium gordonae CIP 6427 | 1998 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 8, Issue:20 | Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis. |
| AID574808 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 2301 horboring rpoB S531L, katG R463L/E217G, gyrA D94N/S95T, rrs A1401G by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID611681 | Antibacterial activity against Escherichia coli at 0.05 mg by agar diffusion method | 2011 | Journal of natural products, Jul-22, Volume: 74, Issue:7 | Bioactive 11,20-epoxy-3,5(16)-diene briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. |
| AID1333143 | Induction of membrane disruption in Mycobacterium bovis BCG ATCC 35734 at 60 uM up to 3 hrs by Sytox green uptake assay | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID1596673 | Bactericidal activity against Staphylococcus aureus ATCC 6538 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID381886 | Antimicrobial activity against Pseudomonas tolaasii by serial dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | A novel sesquiterpene lactone from Centaurea pullata: structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties. |
| AID631060 | Ratio of IC50 for Yersinia pestis KIM6-2082.1+ in PMHD medium supplemented with 100 uM FeCl3 to IC50 for Yersinia pestis KIM6-2082.1+ in Fe-deficient GASTD medium | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID1156885 | Antimicrobial activity against Aspergillus niger MCIM 545 at 100 ug/disc after 48 hrs by agar cup plate method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID1055956 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis ATCC 35822 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1170144 | Antimicrobial activity against Bacillus subtilis DSM 1088 incubated for 24 hrs by disk diffusion method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Antibacterial secondary metabolites from an endophytic fungus, Eupenicillium sp. LG41. |
| AID1079944 | Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] | |||
| AID293799 | Antibacterial activity against Streptococcus faecalis | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives. |
| AID1476362 | Antitubercular activity against bedaquiline resistant Mycobacterium tuberculosis H37Rv after 24 hrs by MABA method | 2017 | Journal of medicinal chemistry, 10-26, Volume: 60, Issue:20 | Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity. |
| AID245270 | Minimum inhibitory concentration against gram negative Klebsiella aerogenes (MTCC 39) using broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17 | Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents. |
| AID277069 | Antibacterial activity against Pseudomonase aeruginosa by measuring zone of inhibition at 30 ug after 24 hrs | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Synthesis of antimicrobial 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines. |
| AID544014 | Antimicrobial activity against Acinetobacter sp. An9 isolate PGS49 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID625284 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID534829 | Antimicrobial activity against Campylobacter fetus subsp. fetus CA80 harboring ciprofloxacin-resistant gene and IMD523-06 pathogenicity island with tet(44) and ant(6)-Ib resistant marker gene in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID400006 | Antimicrobial activity against Bacillus subtilis using distilled water as solvent by agar diffusion test | |||
| AID1477416 | Antibacterial activity against wild type Mycobacterium tuberculosis H37Rv grown in GAST/Fe medium measured on day 14 post inoculation by broth microdilution method | 2017 | Journal of medicinal chemistry, 12-28, Volume: 60, Issue:24 | Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies. |
| AID357044 | Antibacterial activity against Escherichia coli at 10 ug/disk by disk diffusion method | 2001 | Journal of natural products, Jul, Volume: 64, Issue:7 | Isolation and bioactivities of constitutents of the roots of Garcinia atroviridis. |
| AID1201577 | Antibacterial activity against Staphylococcus aureus at 0.5 mg/ml incubated for 18 hrs by well plate technique | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. |
| AID1435648 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 1 after 14 days by micromethod | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. |
| AID245264 | Minimum inhibitory concentration against gram positive Bacillus sphaericus (MTCC 11) using broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17 | Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents. |
| AID532965 | Antimicrobial activity against multidrug-resistant Mycobacterium tuberculosis isolate 9 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | In vitro antituberculosis activities of ACH-702, a novel isothiazoloquinolone, against quinolone-susceptible and quinolone-resistant isolates. |
| AID320033 | Antibacterial activity against Bacillus subtilis by broth dilution method | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3 | Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates. |
| AID400002 | Antimicrobial activity against Bacillus subtilis using pH 4.0 buffer as solvent by agar diffusion test | |||
| AID1241201 | Inhibition of pre-miR-372 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID362712 | Antimicrobial activity against Escherichia coli CGMCC 1.2340 | 2008 | Journal of natural products, Sep, Volume: 71, Issue:9 | Bioactive asterric acid derivatives from the Antarctic ascomycete fungus Geomyces sp. |
| AID562589 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1079949 | Proposed mechanism(s) of liver damage. [column 'MEC' in source] | |||
| AID1456559 | Antibacterial activity against Clostridium sporogenes NICM 2559 assessed as diameter of inhibition zone measured after 20 hrs by agar well diffusion method | |||
| AID1247082 | Antibacterial activity against Bacillus subtilis assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID456080 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1456558 | Antibacterial activity against Bacillus flexus MTCC 2909 assessed as diameter of inhibition zone measured after 20 hrs by agar well diffusion method | |||
| AID637083 | Antibacterial activity against Staphylococcus aureus NRRL B 313 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1296388 | Antimycobacterial activity against multi drug resistant Mycobacterium tuberculosis Praha 131 after 14 days by microdilution method | 2016 | Journal of medicinal chemistry, Mar-24, Volume: 59, Issue:6 | Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. |
| AID311786 | Antibacterial activity against Bacillus subtilis ATCC 10907 by microdilution technique | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | Minor sesquiterpene lactones from Centaurea pullata and their antimicrobial activity. |
| AID534339 | Antimicrobial activity against Burkholderia pseudomallei 1026b after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID370257 | Antimycobacterial activity against Mycobacterium tuberculosis Kurono infected ICR mouse assessed as viable lung bacterial count at 160 mg/kg, po administered once daily measured after 28 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID1156881 | Antimicrobial activity against Bacillus subtilis NCIM 2250 at 100 ug/disc after 24 hrs by agar cup plate method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID1255665 | Antibacterial activity against Escherichia coli ATCC 8739 assessed as growth inhibition at 25 ug/ml after 8 to 24 hrs by agar well diffusion method | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID532987 | Antibacterial activity against Pseudomonas aeruginosa NCIM 5029 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID561100 | Antibacterial activity against Pasteurella multocida BB1034 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1001 bearing tetB gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID442430 | Antimicrobial activity against Salmonella Typhimurium after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID94065 | Compound (isolated from leaves of Cistus monspeliensis) was tested for antimicrobial activity against Klebsiella pneumoniae (ATCC 13883) | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | A simple and rapid method for the differentiation of C-13 manoyl oxide epimers in biologically important samples using GC-MS analysis supported with NMR spectroscopy and computational chemistry results. |
| AID321426 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by microdilution test | 2008 | Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3 | Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1153327 | Antimycobacterial activity against Mycobacterium smegmatis ATCC 19420 after 1 day | 2014 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 24, Issue:13 | Design, synthesis and antimycobacterial activity evaluation of natural oridonin derivatives. |
| AID424338 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH196 harboring Pro406Leu mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1546190 | Antifungal activity against Rhodotorula ingeniosa assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID585433 | Antimicrobial activity against Escherichia coli DH5[alpha] by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID585428 | Antimicrobial activity against oqxAB positive Escherichia coli C600 SW8-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID544288 | Antimicrobial activity against Enterococcus faecalis NKH18 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID723717 | Bactericidal activity against Micrococcus flavus ATCC 10240 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID278532 | Antimicrobial activity against Bifidobacterium thermophilum ATCC 25866 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID460795 | Antibacterial activity against Staphylococcus aureus ATCC 29740 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID283647 | Antibacterial activity against Escherichia coli K12 MG1655 in presence of ascorbic acid by agar dilution method relative to control | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID601168 | Antibacterial activity against Bacillus cereus using 1 x 10'4 CFU/ml inoculum after 24 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID625278 | FDA Liver Toxicity Knowledge Base Benchmark Dataset (LTKB-BD) drugs of no concern for DILI | 2011 | Drug discovery today, Aug, Volume: 16, Issue:15-16 | FDA-approved drug labeling for the study of drug-induced liver injury. |
| AID460796 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 16 to 20 hrs by microdilution susceptibility test | 2010 | Bioorganic & medicinal chemistry, Jan-15, Volume: 18, Issue:2 | The chemical synthesis and antibiotic activity of a diverse library of 2-aminobenzimidazole small molecules against MRSA and multidrug-resistant A. baumannii. |
| AID1055965 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolate X003899 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID424347 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH199 harboring TAA stop codon at nucleotide 241 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID534341 | Antimicrobial activity against Burkholderia pseudomallei Bp227 harboring deleted (bpeAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID464053 | Antibacterial activity against Pseudomonas tolaasii after 48 hrs by serial dilution technique | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Sesquiterpene lactones from Anthemis melanolepis and their antibacterial and cytotoxic activities. Prediction of their pharmacokinetic profile. |
| AID644165 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID565228 | Antimicrobial activity against Mycobacterium chelonae ATCC 35752 by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID258711 | Antibacterial activity against gram positive Bacillus sphaericus (MTCC 11) | 2006 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 16, Issue:1 | Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents. |
| AID568759 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 25177 at 1 ug after 12 days by disc diffusion assay | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | Pitiprolamide, a proline-rich dolastatin 16 analogue from the marine cyanobacterium Lyngbya majuscula from Guam. |
| AID515226 | Antibacterial activity against Staphylococcus aureus at 50 ug/ml after 18 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Anti-tubercular agents. Part 5: synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners. |
| AID673186 | Antimicrobial activity against Staphylococcus aureus MTCC 96 after 24 hrs by agar well diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 22, Issue:15 | Synthesis and biological evaluation of novel 2,4,6-triazine derivatives as antimicrobial agents. |
| AID144025 | In vitro cytotoxicity against Mycobacterium gordonae (CIP 6427) was determined | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12 | N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480. |
| AID92476 | Maximal inhibition against the displacement of Picogreen from fMet-tRNA(fMet) by the aminoglycoside | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6 | Inhibition of bacterial IF2 binding to fMet-tRNA((fMet)) by aminoglycosides. |
| AID424608 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH386 (SCV-58) harboring -1 frameshift mutation at nucleotide 90 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID674379 | Antibacterial activity Staphylococcus aureus ATCC 25923 at 1 mg/ml after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: as a new class of potent antioxidants and antimicrobials--a novel accost to amend biocompatibility. |
| AID464206 | Antibacterial activity against Bacillus subtilis NCIM 2250 after 48 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Synthesis, in vitro antibacterial and antifungal evaluations of new alpha-hydroxyphosphonate and new alpha-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline. |
| AID1235642 | Antibacterial activity against Pseudomonas aeruginosa DSM 22644 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID382586 | Antibacterial activity against Vibrio cholerae assessed as diameter of inhibition zone at 2.0% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID515322 | Antibacterial activity against Escherichia coli at 100 ug/ml after 24 to 48 hrs by cup-plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Synthesis and biological property of some novel 1,3,4-oxadiazoles. |
| AID1179281 | Antimicrobial activity against Salmonella typhimurium MTCC 1251 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID529885 | Antibacterial activity against Staphylococcus aureus RN4220 by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID294555 | Antimicrobial activity against Candida tropicalis IP 2031 at 10 ug by disk diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Rapid synthesis of sulfone derivatives as potential anti-infectious agents. |
| AID245252 | Minimum inhibitory concentration against gram positive Bacillus subtilis (MTCC 441) using broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17 | Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents. |
| AID540213 | Half life in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID569258 | Antimycobacterial activity against Mycobacterium avium subsp. hominissuis 104 | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID625372 | Antibacterial activity against Staphylococcus aureus ATCC 25825 after 24 hrs by twofold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Synthesis, stereochemistry and in vitro antimicrobial evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-4-phenyl-2,3-dihydrothiazoles. |
| AID683687 | Kinetic solubility of the compound at pH 7.4 | 2012 | European journal of medicinal chemistry, Nov, Volume: 57 | The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives. |
| AID532022 | Antimicrobial activity against Mycobacterium ulcerans 1059 harboring pTY60K containing pMH94 carrying the luxAB gene under the hsp60 promoter after 14 days determined according to CFU count by bioluminescence method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID326544 | Antimicrobial activity against Mycobacterium abscessus R50 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID723724 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID715627 | Antibacterial activity against Pseudomonas aeruginosa MTCC 7952 after 24 hrs by serial dilution method | 2012 | European journal of medicinal chemistry, Nov, Volume: 57 | Synthesis, characterization, biological evaluation and QSAR studies of 11-p-substituted phenyl-12-phenyl-11a,12-dihydro-11H-indeno[2,1-c][1,5]benzothiazepines as potential antimicrobial agents. |
| AID258710 | Antibacterial activity against gram positive Bacillus subtilis MTCC 441 | 2006 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 16, Issue:1 | Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents. |
| AID456081 | Antibacterial activity against Escherichia coli ATCC 35210 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID601174 | Antibacterial activity against Salmonella typhi using 1 x 10'4 CFU/ml inoculum after 24 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID633850 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID341105 | Antimicrobial activity against streptomycin-resistant Yersinia pestis mutant | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID534340 | Antimicrobial activity against Burkholderia pseudomallei Bp50 harboring deleted (amrRAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID341091 | Antimicrobial activity against antibiotic-resistant Yersinia pestis mutant in human serum assessed as decrease in bacterial population after 24 hrs | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID774294 | Antimycobacterial activity against cycloserine-resistant Mycobacterium tuberculosis ATCC 35826 | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID737335 | Antimicrobial activity against Staphylococcus aureus ATCC 29513 at 500 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID1186774 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 30 ug/ml after 24 hrs by agar well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17 | Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: synthesis, characterization and evaluation of anticancer and antimicrobial activities. |
| AID515241 | Antibacterial activity against Pseudomonas aeruginosa at 50 ug/ml after 18 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Anti-tubercular agents. Part 5: synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners. |
| AID1079941 | Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source] | |||
| AID1566486 | Binding affinity to biotinylated pre-miRNA-21 (unknown origin) by SPR analysis | 2019 | ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5 | Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. |
| AID608669 | Antibacterial activity against Salmonella Typhimurium assessed as zone of inhibition at 500 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID404903 | Antibacterial activity against Streptococcus bovis ATCC 33317 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID644174 | Antibacterial activity against Micrococcus flavus ATCC 10240 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID285339 | Antimicrobial activity against streptomycin-resistant Escherichia coli J53 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID279864 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 1000 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID70151 | Minimum inhibitory concentration against Escherichia coli (ATCC 25922) | 2001 | Bioorganic & medicinal chemistry letters, Mar-26, Volume: 11, Issue:6 | Structure elucidation and conformational properties of a novel bioactive clerodane diterpene using a combination of high field NMR spectroscopy, computational analysis and X-ray diffraction. |
| AID732683 | Cytotoxicity against human HEK293 cells assessed as inhibition of cell viability after 24 hrs by MTT assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 23, Issue:5 | Syntheses of lipophilic chalcones and their conformationally restricted analogues as antitubercular agents. |
| AID1247102 | Antibacterial activity against Enterobacter aerogenes after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID358133 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by twofold serial dilution method | |||
| AID1224521 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 8666/2010 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID442408 | Antimicrobial activity against Bacillus cereus at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID540183 | Antibacterial activity against Staphylococcus aureus NCIM 2492 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis and anti-tubercular and antimicrobial activities of some 2r,4c-diaryl-3-azabicyclo[3.3.1]nonan-9-one N-isonicotinoylhydrazone derivatives. |
| AID585419 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W281-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID311785 | Antibacterial activity against Micrococcus flavus ATCC 10240 by microdilution technique | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | Minor sesquiterpene lactones from Centaurea pullata and their antimicrobial activity. |
| AID625375 | Antibacterial activity against Escherichia coli ATCC 25835 after 24 hrs by twofold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Synthesis, stereochemistry and in vitro antimicrobial evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-4-phenyl-2,3-dihydrothiazoles. |
| AID294742 | Antibacterial activity against Salmonella typhi at 0.5% (w/v) concentration after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID376312 | Antibacterial activity against Pseudomonas savastanoi pv. savastanoi CCM 3580 assessed as total inhibition of cell growth/spore germination after 24 hrs | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Antimicrobial dialkylresorcinols from Pseudomonas sp. Ki19. |
| AID1156891 | Antimicrobial activity against Aspergillus niger MCIM 545 after 24 hrs by NCCLS M7-A5 method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID732685 | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as growth inhibition measured every 24 hrs by BACTEC radiosusceptibility assay | 2013 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 23, Issue:5 | Syntheses of lipophilic chalcones and their conformationally restricted analogues as antitubercular agents. |
| AID396001 | Antimicrobial activity against Mycoplasma putrefaciens Jordanian isolates after 24 hrs by twofold serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. |
| AID665396 | Antibacterial activity against Staphylococcus aureus MTCC 7443 after 24 hrs by serial dilution technique | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Synthesis, characterization, antimicrobial activities and QSAR studies of some 10a-phenylbenzo[b]indeno[1,2-e][1,4]thiazin-11(10aH)-ones. |
| AID574811 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis H37Rv by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID723715 | Bactericidal activity against Listeria monocytogenes NCTC 7973 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID424826 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH298 harboring Gly664Val mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID279883 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 500 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID464047 | Antibacterial activity against Bacillus cereus clinical isolate after 48 hrs by serial dilution technique | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Sesquiterpene lactones from Anthemis melanolepis and their antibacterial and cytotoxic activities. Prediction of their pharmacokinetic profile. |
| AID424580 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH332 (SCV-4) harboring Ala655Glu mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1204390 | Antibacterial activity against Bacillus subtilis assessed as lowest concentration required to reduce growth by 1% after 8 hrs by ELISA plate reader analysis relative to control | 2015 | European journal of medicinal chemistry, Jun-05, Volume: 97 | Benzaldehyde Schiff bases regulation to the metabolism, hemolysis, and virulence genes expression in vitro and their structure-microbicidal activity relationship. |
| AID1201574 | Antibacterial activity against Escherichia coli at 1 mg/ml incubated for 18 hrs by well plate technique | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. |
| AID530051 | Antimicrobial activity against Staphylococcus aureus 286607-R1 harboring wild type gyrB by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID528087 | Antibacterial activity against Salmonella typhi ATCC 25021 after 24 hrs by serial dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Efficient synthesis, spectral analysis and antimicrobial studies of nitrogen and sulfur containing spiro heterocycles from 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones. |
| AID644172 | Antibacterial activity against Staphylococcus aureus ATCC 6538 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1091741 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as growth arrest at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID1245992 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID456357 | Antibacterial activity against Pseudomonas fluorescens NCIB 3756 after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID561110 | Antibacterial activity against Pasteurella multocida BB1044 harboring plasmid pB1000 bearing blaROB-1 gene, plasmid 1006 bearing tetO gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID200678 | Antibacterial activity against gram negative bacteria Salmonella typhi was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID464050 | Antibacterial activity against Agrobacterium tumefaciens A 281 after 48 hrs by serial dilution technique | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Sesquiterpene lactones from Anthemis melanolepis and their antibacterial and cytotoxic activities. Prediction of their pharmacokinetic profile. |
| AID1596681 | Bactericidal activity against Salmonella typhimurium ATCC 13311 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID1653582 | Anti-leprotic activity against Mycobacterium leprae infected in BALB/c weanling mouse assessed as bacteria killing at 150 mg/kg, ip administrated for 60 days and measured after 1 year by most probable number technique analysis relative to control | 2019 | Bioorganic & medicinal chemistry, 07-01, Volume: 27, Issue:13 | Insights of synthetic analogues of anti-leprosy agents. |
| AID1125791 | Antibacterial activity against Staphylococcus aureus MTCC 4102 assessed as diameter of growth inhibition zone at 10 ug/ml after 20 hrs by agar disc diffusion method | 2014 | European journal of medicinal chemistry, Apr-22, Volume: 77 | New polyfunctional imidazo[4,5-C]pyridine motifs: synthesis, crystal studies, docking studies and antimicrobial evaluation. |
| AID294735 | Antibacterial activity against Aeromonas hydrophila at 0.25% (w/v) concentration after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID530250 | Antimicrobial activity against dksA deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 10 ug/ml after 3 hrs by time kill analysis relative to wild type | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID424339 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH198 harboring Gly452Ser mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID561105 | Antibacterial activity against Pasteurella multocida BB1039 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID535773 | Antimicrobial activity against Mycobacterium ulcerans 1059 harboring pTY60K carrying the luxAB gene under the hsp60 promoter agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID595282 | Antimicrobial activity against Escherichia coli ATCC 26032 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, spectral, crystal structure and in vitro antimicrobial evaluation of imidazole/benzotriazole substituted piperidin-4-one derivatives. |
| AID1456564 | Antibacterial activity against Klebsiella pneumoniae PTCC 1053 assessed as diameter of inhibition zone measured after 20 hrs by agar well diffusion method | |||
| AID440767 | Antibacterial activity against Bacillus thuringiensis after 24-48 hrs by microdilution susceptibility test | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | Enaminonitrile in heterocyclic synthesis: synthesis and antimicrobial evaluation of some new pyrazole, isoxazole and pyrimidine derivatives incorporating a benzothiazole moiety. |
| AID279898 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 500 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID456437 | Antibacterial activity against Escherichia coli NCIB 86 after 72 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID449212 | Protection index, ratio of MNTD for african green monkey Vero cells to MIC for Mycobacterium tuberculosis CIP 103471 | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation. |
| AID326551 | Antimicrobial activity against Mycobacterium fortuitum V13 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID404902 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID648386 | Antibacterial activity against Micrococcus luteus at 10 ug/disc after 24 hrs by disc diffusion assay | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID1079931 | Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] | |||
| AID419398 | Antibacterial activity against Bacillus subtilis MTCC 8509 at 10 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID1600166 | Antibacterial activity against Escherichia coli NCIM 2574 assessed as zone of inhibition at 80 ug/well incubated for 24 to 48 hrs by by agar well diffusion method | 2019 | European journal of medicinal chemistry, Oct-01, Volume: 179 | Synthesis of new thiazolyl-pyrazolyl-1,2,3-triazole derivatives as potential antimicrobial agents. |
| AID774299 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 incubated for 10 days under low oxygen condition followed by normoxic environment for 28 hrs by low oxygen recovery assay | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID1247091 | Antibacterial activity against Salmonella typhimurium after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID245279 | Minimum inhibitory concentration against gram positive Staphylococcus aureus (MTCC 96) using broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 15, Issue:17 | Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents. |
| AID565747 | Antimicrobial activity against Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID338746 | Antimicrobial activity against Mycobacterium smegmatis after 48 hrs by twofold serial broth dilution technique | |||
| AID608665 | Antibacterial activity against Staphylococcus aureus assessed as zone of inhibition at 500 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID456352 | Antibacterial activity against Bacillus stearothermophilus NCIB 8222 after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID1333172 | Antimycobacterial activity against Mycobacterium bovis BCG ATCC 35734 after 5 days by broth dilution assay | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID615476 | Antimicrobial activity against Escherichia coli at 50 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID381882 | Antimicrobial activity against Bacillus subtilis ATCC 10907 by serial dilution technique | 2008 | Bioorganic & medicinal chemistry, Apr-01, Volume: 16, Issue:7 | A novel sesquiterpene lactone from Centaurea pullata: structure elucidation, antimicrobial activity, and prediction of pharmacokinetic properties. |
| AID608666 | Antibacterial activity against Bacillus subtilis assessed as zone of inhibition at 1000 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID1241205 | Inhibition of pre-miR-372 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID376320 | Antibacterial activity against Salmonella enteritidis ATCC 13076 after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID747758 | Antibacterial activity against Escherichia coli | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID1546105 | Antimicrobial activity against Bacillus subtilis | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID574806 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 625 horboring rpoB S531L/G566R/I569L, katG S315T/R463L, gyrA A90V/S95T, rrs A1401G by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID1596669 | Bactericidal activity against Bacillus cereus clinical isolate incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID545530 | Antibacterial activity against Staphylococcus aureus ATCC 25825 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide. |
| AID1546201 | Antifungal activity against Candida albicans MTCC 277 after 48 hrs by NCCLS protocol based method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID409957 | Inhibition of bovine liver MAOA | 2008 | Journal of medicinal chemistry, Nov-13, Volume: 51, Issue:21 | Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. |
| AID1159122 | Antimicrobial activity against Bacillus cereus ATCC 11778 for 24 hrs by microdillution method | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID370071 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 35822 after 14 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID595280 | Antimicrobial activity against Bacillus subtilis ATCC 530 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, spectral, crystal structure and in vitro antimicrobial evaluation of imidazole/benzotriazole substituted piperidin-4-one derivatives. |
| AID636963 | Antibacterial activity against Bacillus idosus B 241 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID440545 | Antibacterial activity against Escherichia coli ATCC 35218 | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23 | Discovery of Trp-His and His-Arg analogues as new structural classes of short antimicrobial peptides. |
| AID379962 | Antimicrobial activity against Staphylococcus aureus at 37 degC after 24 hrs in dark | 2006 | Journal of natural products, Dec, Volume: 69, Issue:12 | Low-abundance kutznerides from Kutzneria sp. 744. |
| AID464059 | Antibacterial activity against Proteus mirabilis clinical isolate after 48 hrs by serial dilution technique | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Sesquiterpene lactones from Anthemis melanolepis and their antibacterial and cytotoxic activities. Prediction of their pharmacokinetic profile. |
| AID528085 | Antibacterial activity against Staphylococcus aureus ATCC 25930 after 24 hrs by serial dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Efficient synthesis, spectral analysis and antimicrobial studies of nitrogen and sulfur containing spiro heterocycles from 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones. |
| AID379427 | Antibacterial activity against Bacillus subtilis DSM2109 at 5 ug after 24 hrs by agar diffusion assay | 2006 | Journal of natural products, Feb, Volume: 69, Issue:2 | Cytotoxic isomalabaricane triterpenes from the marine sponge Rhabdastrella globostellata. |
| AID278551 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium infantis ATCC 15697 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID601176 | Antibacterial activity against Bacillus subtilis assessed as 99.5% bacterial killing using 1 x 10'4 CFU/ml inoculum after 72 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID587243 | Antimicrobial activity against Klebsiella pneumoniae DSM 681 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID723712 | Bactericidal activity against Escherichia coli ATCC 35210 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID279902 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 31.3 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID278537 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium breve ATCC 15700 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID648380 | Antibacterial activity against Salmonella paratyphi B after 24 hrs by twofold serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID370255 | Antimycobacterial activity against Mycobacterium tuberculosis Kurono infected ICR mouse assessed as viable lung bacterial count at 40 mg/kg, po administered once daily measured after 28 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID321430 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs by microdilution test | 2008 | Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3 | Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID428872 | Antibacterial activity against Escherichia coli JM109 carrying pMCL-BE by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID530287 | Antimicrobial activity against PR-39-resistant sbmA-deficient Salmonella enterica serovar Typhimurium LT2 DA12088 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID774839 | Antibacterial activity against Escherichia coli ATCC 25922 at 0.5 to 1 mg/ml at 37 degC after 18 hrs by well plate method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis, characterization and molecular docking studies of some new 1,3,4-oxadiazolines bearing 6-methylpyridine moiety for antimicrobial property. |
| AID419568 | Antibacterial activity against Bacillus stearothermophilus MTCC 8508 at 100 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID541855 | Antimicrobial activity against Escherichia coli ATCC 29522 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID1075579 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 254992 after 18 to 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents. |
| AID396002 | Antimicrobial activity against Mycoplasma putrefaciens KS1 after 24 hrs by twofold serial dilution method | 2007 | Antimicrobial agents and chemotherapy, Sep, Volume: 51, Issue:9 | In vitro susceptibilities of Mycoplasma putrefaciens field isolates. |
| AID1233489 | Antimicrobial activity against Staphylococcus aureus MTCC 96 assessed as inhibition of visual microbial growth incubated for 24 hrs at 37 degC | 2015 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 25, Issue:14 | Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. |
| AID584114 | Antibacterial activity against Escherichia coli KAM32 harboring Staphylococcus aureus cloned pSP72 lmrS by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus. |
| AID65061 | Lethal dose required to kill 90% of the Escherichia coli K12 (ATCC 25868) cell population | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID562591 | Antimicrobial activity against Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1546642 | Antibacterial activity against Bacillus subtilis MTCC 441 assessed as diameter of zone of inhibition at 200 ug/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID574800 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 2474 obtained from sputum of patient at 1 ug/ml by Bactec MGIT960 modified proportion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID268908 | Antibacterial activity against Mycobacterium tuberculosis 103471 | 2006 | Journal of medicinal chemistry, Aug-10, Volume: 49, Issue:16 | Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity. |
| AID268909 | Cytotoxicity against Vero cell line | 2006 | Journal of medicinal chemistry, Aug-10, Volume: 49, Issue:16 | Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity. |
| AID1236039 | Antibacterial activity against Escherichia coli assessed as growth inhibition at 200 ug/ml after 24 hrs by paper disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Bisabolane-Type Sesquiterpenoids from the Whole Plant of Parasenecio rubescens. |
| AID1125785 | Antibacterial activity against Pseudomonas aeruginosa MTCC 4727 assessed as diameter of growth inhibition zone at 10 ug/ml after 20 hrs by agar disc diffusion method | 2014 | European journal of medicinal chemistry, Apr-22, Volume: 77 | New polyfunctional imidazo[4,5-C]pyridine motifs: synthesis, crystal studies, docking studies and antimicrobial evaluation. |
| AID1179277 | Antimicrobial activity against Bacillus subtilis MTCC 441 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID515918 | Antibacterial activity against isoniazid-resistant Mycobacterium tuberculosis after 7 days by microplate alamar blue assay | 2010 | Bioorganic & medicinal chemistry, Oct-15, Volume: 18, Issue:20 | Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring. |
| AID321429 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by microdilution test | 2008 | Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3 | Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID532980 | Antibacterial activity against Escherichia coli DH5alpha in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID434665 | Antibacterial activity against Klebsiella pneumoniae ATCC 15490 after 24 hrs by twofold serial dilution method | 2009 | Bioorganic & medicinal chemistry letters, May-15, Volume: 19, Issue:10 | Design, synthesis and biological evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-1,3-thiazolidin-4-ones as a new class of antimicrobial agents. |
| AID442420 | Antimicrobial activity against Pseudomonas aeruginosa at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID408873 | Protection index, ratio of MNTD50 for african green monkey Vero cells to MIC for Mycobacterium tuberculosis 103471 | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID442422 | Antimicrobial activity against Salmonella Typhimurium at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID587764 | Antimicrobial activity against recombinant Mycobacterium ulcerans Mu1059 expressing luxAB from vibrio harveyi infected BALB/c mouse assessed as reduction in foodpad CFU count after 1 week relative to basal level | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Using bioluminescence to monitor treatment response in real time in mice with Mycobacterium ulcerans infection. |
| AID656233 | Antimycobacterial activity against isoniazid-, rifampin-, ofloxacin-, ethambutol-, streptomycin-resistant Mycobacterium tuberculosis after 16 to 24 hrs by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. |
| AID456439 | Antibacterial activity against Shigella dysenteriae after 72 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID1428255 | Antibacterial activity against Escherichia coli RCMB 000106 assessed as zone of inhibition at 30 ug/ml | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold. |
| AID1079947 | Comments (NB not yet translated). [column 'COMMENTAIRES' in source] | |||
| AID275056 | Antibacterial activity against Escherichia coli pTMV19 in presence of mevalonate | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25 | Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin. |
| AID456084 | Antibacterial activity against Proteus mirabilis after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID747764 | Antibacterial activity against Streptococcus faecalis after 24 hrs by broth dilution method | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID1156689 | Antimicrobial activity against Salmonella typhimurium MTCC 1251 assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID774296 | Antimycobacterial activity against streptomycin-resistant Mycobacterium tuberculosis ATCC 35820 | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID306204 | Antimicrobial activity against Mycobacterium smegmatis | 2007 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 17, Issue:5 | Anti-mycobacterial activity of a bis-sulfonamide. |
| AID424610 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH421 harboring Pro404Arg mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID600681 | Bactericidal activity against Micrococcus flavus ATCC 10240 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1054727 | Antibacterial activity against Staphylococcus aureus Rosenbach ATCC 9144 after overnight incubation by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 | Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley. |
| AID289153 | Cytotoxicity against Vero cells | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines. |
| AID723718 | Bactericidal activity against Staphylococcus aureus ATCC 6538 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID278545 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium animalis ATCC 27536 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID341090 | Antibacterial activity against Yersinia pestis delta CO92 by broth macrodilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID1055937 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv under normoxic condition after 7 days by MABA assay in presence of 10% fetal bovine serum | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID416839 | Antimycobacterial activity against Mycobacterium ulcerans isolate CU001 | 2007 | Antimicrobial agents and chemotherapy, Oct, Volume: 51, Issue:10 | Orally administered combined regimens for treatment of Mycobacterium ulcerans infection in mice. |
| AID775492 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition after 5 days by microplate Alamar Blue assay | 2013 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 23, Issue:21 | Synthesis, characterization and in vitro biological evaluation of some novel 1,3,5-triazine-Schiff base conjugates as potential antimycobacterial agents. |
| AID424577 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH336 (SCV-8) harboring His438Asn mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1474167 | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring verified drug-induced liver injury concern status | 2016 | Drug discovery today, Apr, Volume: 21, Issue:4 | DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. |
| AID1279001 | Antibacterial activity against methicillin-resistant Staphylococcus aureus incubated for 20 hrs by microbroth dilution method | 2016 | Bioorganic & medicinal chemistry, Mar-15, Volume: 24, Issue:6 | Synthesis of fluorinated carbazoles via C-H arylation catalyzed by Pd/Cu bimetal system and their antibacterial activities. |
| AID321427 | Antibacterial activity against Bacillus subtilis ATCC 10907 after 24 hrs by microdilution test | 2008 | Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3 | Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1104323 | Antibacterial activity against Micrococcus flavus ATCC 10240 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1456556 | Antifungal activity against Aspergillus terreus MTCC 1782 assessed as diameter of inhibition zone after 4 days by agar well diffusion method | |||
| AID419566 | Antibacterial activity against Bacillus stearothermophilus MTCC 8508 at 10 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID279890 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 3.9 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID401462 | Antimicrobial activity against Klebsiella pneumoniae ATCC 10031 by agar-dilution streak method | |||
| AID1156678 | Antimicrobial activity against Salmonella typhimurium MTCC 1251 assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID434662 | Antibacterial activity against Bacillus subtilis ATCC 451 after 24 hrs by twofold serial dilution method | 2009 | Bioorganic & medicinal chemistry letters, May-15, Volume: 19, Issue:10 | Design, synthesis and biological evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-1,3-thiazolidin-4-ones as a new class of antimicrobial agents. |
| AID400003 | Antimicrobial activity against Staphylococcus aureus using pH 4.0 buffer as solvent by agar diffusion test | |||
| AID544008 | Antimicrobial activity against Acinetobacter lwoffii isolate C2 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID301998 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | 2007 | Bioorganic & medicinal chemistry, Dec-15, Volume: 15, Issue:24 | Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase. |
| AID440601 | Antibacterial activity against Bacillus subtilis assessed as zone of inhibition diameter at 1 mg/mL after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | Enaminonitrile in heterocyclic synthesis: synthesis and antimicrobial evaluation of some new pyrazole, isoxazole and pyrimidine derivatives incorporating a benzothiazole moiety. |
| AID530234 | Antimicrobial activity against wild-type Mycobacterium bovis BCG by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID424589 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH370 (SCV-42) harboring TAA stop codon at nucleotide 229 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID68983 | Antibacterial activity against gram negative bacteria Escherichia coli was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID1054723 | Antibacterial activity against Salmonella typhimurium (Loeffler) Castellani and Chalmers ATCC 14028 after overnight incubation by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 | Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley. |
| AID1168612 | Antibacterial activity against Coagulase positive Staphylococcus incubated for 24 hrs by agar microdilution method | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets. |
| AID539694 | Antifungal activity against Pseudomonas aeruginosa MTCC 741 by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Indium(III) chloride catalyzed three-component coupling reaction: a novel synthesis of 2-substituted aryl(indolyl)kojic acid derivatives as potent antifungal and antibacterial agents. |
| AID644178 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID669186 | Antitubercular activity against Mycobacterium tuberculosis H37Rv in aerobic conditions after 7 days by microplate-based alamar blue assay | 2012 | Journal of medicinal chemistry, Apr-26, Volume: 55, Issue:8 | Structure-based design of novel benzoxazinorifamycins with potent binding affinity to wild-type and rifampin-resistant mutant Mycobacterium tuberculosis RNA polymerases. |
| AID144298 | In vitro cytotoxicity against Mycobacterium marinum (CIP 6423) was determined | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12 | N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480. |
| AID321432 | Antibacterial activity against Enterobacter cloacae after 24 hrs by microdilution test | 2008 | Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3 | Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1241214 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay in presence of 100-fold excess of 15-mer DNA | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID238131 | Binding dissociation constant towards 3'-Fl-AM1A-Rhd in Bacillus subtilis tyrS | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Fluorescence resonance energy transfer studies of aminoglycoside binding to a T box antiterminator RNA. |
| AID277997 | Antibacterial activity against Bacillus subtilis | 2007 | Journal of natural products, Feb, Volume: 70, Issue:2 | Antimicrobial ambiguines from the cyanobacterium Fischerella sp. collected in Israel. |
| AID424596 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH358 (SCV-30) harboring -1 frameshift mutation at nucleotide 423 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID677139 | Antimicrobial activity against Mycobacterium smegmatis by broth microdilution assay | 2012 | Bioorganic & medicinal chemistry, Sep-01, Volume: 20, Issue:17 | Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola. |
| AID562383 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1463961 | Antimycobacterial activity MDR/XDR against Mycobacterium tuberculosis isolate 7357/1998 incubated for 14 days by micromethod | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents. |
| AID1596672 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID637027 | Antibacterial activity against Bacillus mycoides DSMZ 274 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID523397 | Antimicrobial activity against amikacin-susceptible Nocardia farcinica IFM 10152 harboring 16s rRNA A1408G mutant after 3 days by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic. |
| AID637032 | Antibacterial activity against Micrococcus luteus ATCC 9631 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID588122 | Ratio of MIC for Streptococcus pyogenes 12RF transconjugant harboring ermB and tetW gene from Streptococcus suis UD to wild type Streptococcus suis UD | 2011 | Antimicrobial agents and chemotherapy, Feb, Volume: 55, Issue:2 | Different genetic elements carrying the tet(W) gene in two human clinical isolates of Streptococcus suis. |
| AID382583 | Antibacterial activity against Escherichia coli assessed as diameter of inhibition zone at 2.0% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID1546649 | Antibacterial activity against Escherichia coli MTCC 443 assessed as reduction in microbial growth after 24 hrs by CLSI based microdilution method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID1247095 | Antibacterial activity against Shigella flexneri after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID1245988 | Antimicrobial activity against Erwinia amylovora 1501 after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID278529 | Antimicrobial activity against Bifidobacterium longum R0175 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID382578 | Antibacterial activity against Vibrio cholerae assessed as diameter of inhibition zone at 0.5% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID496398 | Antibacterial activity against azide-resistant Escherichia coli J53 TET1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID144448 | In vitro cytotoxicity against Mycobacterium smegmatis CIP (103599) was determined | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12 | N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480. |
| AID442428 | Antimicrobial activity against Pseudomonas aeruginosa after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID203040 | Antibacterial activity was evaluated against shigella. | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID625374 | Antibacterial activity against Salmonella typhi ATCC 24915 after 24 hrs by twofold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Synthesis, stereochemistry and in vitro antimicrobial evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-4-phenyl-2,3-dihydrothiazoles. |
| AID1247097 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID1075582 | Antimicrobial activity against Staphylococcus aureus NRRL B-767 after 18 to 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents. |
| AID515917 | Antibacterial activity against rifampicin-resistant Mycobacterium tuberculosis after 7 days by microplate alamar blue assay | 2010 | Bioorganic & medicinal chemistry, Oct-15, Volume: 18, Issue:20 | Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring. |
| AID625445 | Antimicrobial activity against Bacillus subtilis MTCC 441 by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Iodine-catalyzed conjugate addition of indoles onto en-1,4-dione: a novel synthesis of 3-(1-(1H-indol-3-yl)-2-oxo-2-phenylethyl)indolin-2-ones as antibacterial and antifungal agents. |
| AID648374 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after 24 hrs by twofold serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID601171 | Antibacterial activity against Staphylococcus aureus using 1 x 10'4 CFU/ml inoculum after 24 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID716925 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 500 ug/mL after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core. |
| AID1255669 | Antibacterial activity against Salmonella abony NCTC 6017 assessed as growth inhibition at 25 ug/ml after 8 to 24 hrs by agar well diffusion method | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID1428252 | Antibacterial activity against Staphylococcus aureus RCMB 000108 assessed as zone of inhibition at 30 ug/ml | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold. |
| AID358876 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 35818 at 5 ug/disk by disk diffusion susceptibility assay | 2001 | Journal of natural products, Mar, Volume: 64, Issue:3 | Pitipeptolides A and B, new cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. |
| AID1247089 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID442409 | Antimicrobial activity against Micrococcus flavus at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1083178 | Bactericidal activity against mixture of two strains of Erwinia amylovora 295/93 and 763 inoculated in Malus x domestica cv. Gala flowers assessed as prevention of infection at 0.06% applied two times at 2 hr after bacterial exposure measured after 8 to 1 | 2012 | Journal of agricultural and food chemistry, Dec-12, Volume: 60, Issue:49 | Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora. |
| AID544285 | Antimicrobial activity against Enterococcus faecalis NKH15 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID94048 | Tested for the antimicrobial activity as minimum inhibitory concentration against Klebsiella pneumoniae ATCC 13883 | 2002 | Bioorganic & medicinal chemistry letters, Mar-11, Volume: 12, Issue:5 | New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation. |
| AID311787 | Antibacterial activity against Pseudomonas tolaasii by microdilution technique | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | Minor sesquiterpene lactones from Centaurea pullata and their antimicrobial activity. |
| AID1054724 | Antibacterial activity against Salmonella sp. ATCC 700623 after overnight incubation by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 | Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley. |
| AID565744 | Antimicrobial activity against Enterococcus faecium expressing VanA gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID294964 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID523398 | Antimicrobial activity against amikacin-susceptible Nocardia farcinica IFM 10152 harboring 16s rRNA A1408G mutant after 5 days by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic. |
| AID1054725 | Antibacterial activity against Escherichia coli (Migula) Castellani and Chalmers ATCC 25922 after overnight incubation by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 | Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley. |
| AID445333 | Selectivity for Mycobacterium tuberculosis H37Rv over human A549 cells | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID562238 | Antimycobacterial activity against Mycobacterium smegmatis assessed as growth inhibition in mid-logarithmic phase by spectrophotometry | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria. |
| AID637084 | Antibacterial activity against Sarcina lutea ATCC 9341 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1565880 | Antibacterial activity against methicillin-resistant Staphylococcus aureus N315 assessed as growth inhibition measured after 24 hrs by two-fold broth dilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | Design, synthesis and biological evaluation of novel diazaspiro[4.5]decan-1-one derivatives as potential chitin synthase inhibitors and antifungal agents. |
| AID279887 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 31.3 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID656231 | Antimycobacterial activity against isoniazid-, rifampin-, ofloxacin-, ethambutol-resistant Mycobacterium tuberculosis after 16 to 24 hrs by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. |
| AID448070 | Antibacterial activity against Xanthomonas axonopodis at 50 mg/L after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Design, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)quinoline-3-carboxylic acid derivatives. |
| AID283649 | Antibacterial activity against Escherichia coli K12 W3110 | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID637025 | Antibacterial activity against Bacillus idosus B 241 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID320036 | Antibacterial activity against Escherichia coli by broth dilution method | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3 | Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates. |
| AID585422 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W245-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID733711 | Antibacterial activity against Micrococcus luteus MTCC 106 at 1 mg/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID370264 | Antimycobacterial activity against Mycobacterium tuberculosis Kurono infected ICR mouse assessed as reduction in viable lung bacterial count at 40 mg/kg, po administered once daily measured after 28 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID408874 | Cytotoxicity against african green monkey Vero cells after 5 days | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID283644 | Sensitivity of Escherichia coli K12 MG1655 in presence of 25 mM histidine by disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID1143268 | Antimycobacterial activity against rifampin-resistant Mycobacterium tuberculosis 19000 assessed as growth inhibition after 2 to 3 weeks by turbidometry | 2014 | Journal of medicinal chemistry, Jun-12, Volume: 57, Issue:11 | Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. |
| AID424611 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH288 harboring Gly617Asp mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID584116 | Ratio of MIC for Escherichia coli KAM32 harboring cloned pSP72 lmrS to MIC for Escherichia coli KAM32 harboring pSP72 | 2010 | Antimicrobial agents and chemotherapy, Dec, Volume: 54, Issue:12 | LmrS is a multidrug efflux pump of the major facilitator superfamily from Staphylococcus aureus. |
| AID326542 | Antimicrobial activity against Mycobacterium abscessus NTU446 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID1511408 | Antibacterial activity against Ralstonia solanacearum assessed as reduction in bacterial cell growth incubated for 24 hrs by filter paper assay | 2019 | Bioorganic & medicinal chemistry, 11-01, Volume: 27, Issue:21 | Synthesis and biological evaluation of calycanthaceous alkaloid analogs. |
| AID268910 | Protection index, cytotoxicity against Vero cell line/antibacterial activity against Mycobacterium tuberculosis 103471 | 2006 | Journal of medicinal chemistry, Aug-10, Volume: 49, Issue:16 | Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity. |
| AID1255675 | Antibacterial activity against Salmonella abony NCTC 6017 after 24 to 48 hrs | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID1594068 | Antibacterial activity against Escherichia coli assessed as reduction in bacterial cell viability incubated for 20 to 24 hrs by REMA method | 2019 | Bioorganic & medicinal chemistry, 06-15, Volume: 27, Issue:12 | Design, synthesis, in-silico studies and biological screening of quinazolinone analogues as potential antibacterial agents against MRSA. |
| AID715625 | Antibacterial activity against Staphylococcus aureus MTCC 7443 after 24 hrs by serial dilution method | 2012 | European journal of medicinal chemistry, Nov, Volume: 57 | Synthesis, characterization, biological evaluation and QSAR studies of 11-p-substituted phenyl-12-phenyl-11a,12-dihydro-11H-indeno[2,1-c][1,5]benzothiazepines as potential antimicrobial agents. |
| AID648373 | Antibacterial activity against Staphylococcus aureus MTCC 96 after 24 hrs by twofold serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID1577339 | Antimycobacterial activity against multi-drug resistant Mycobacterium tuberculosis 8666/2010 after 14 days | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. |
| AID429088 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolates from tuberculosis patient assessed as percent resistant isolates at 4 ug/ml by absolute-concentration method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Prevalence of and molecular basis for tuberculosis drug resistance in the Republic of Georgia: validation of a QIAplex system for detection of drug resistance-related mutations. |
| AID719307 | Antimicrobial activity against Candida albicans NCIM 3471 by broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID1104322 | Antibacterial activity against clinical isolate Bacillus cereus at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID601600 | Antibacterial activity against Gordonia sp. isolate Fs48 at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID644169 | Antibacterial activity against Enterobacter cloacae human isolate after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1545439 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as diameter of zone inhibition at 30 ug/ml | 2019 | Bioorganic & medicinal chemistry, 04-01, Volume: 27, Issue:7 | Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances. |
| AID733702 | Antibacterial activity against Shigella flexneri MTCC 1457 after 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID245105 | In vitro minimum inhibitory concentration of compound against Staphylococcus aureus ATCC 49951 (Smith) | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2 | Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones. |
| AID1091738 | Antibacterial activity against Chromobacterium violaceum MTCC 2656 assessed as growth arrest at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID424335 | Antibacterial activity against fusidic acid-susceptible wild type Staphylococcus aureus 8325-4 after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1463958 | Antimycobacterial activity MDR/XDR against Mycobacterium tuberculosis isolate Praha 131 incubated for 14 days by micromethod | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents. |
| AID1546189 | Antifungal activity against Penicillium assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID644175 | Antibacterial activity against Listeria monocytogenes NCTC 7973 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID285338 | Antimicrobial activity against streptomycin-resistant Escherichia coli J53 transconjugant with qnrA1 producing urinary specimen isolate 13.52 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID737331 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 at 1000 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID283643 | Decrease in sensitivity of Escherichia coli K12 MG1655 assessed as reduction in zone of inhibition in presence of 10 mM ascorbic acid by disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID1324371 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | Novel substituted hydrazono indolo[2,1-b]quinazoline-6,12-dione analogues as cytostatic agents: Synthesis, crystal structure, biological evaluation and molecular docking studies. |
| AID1435651 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 9449/2007 after 14 days by micromethod | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. |
| AID278536 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium bifidum BB12 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1091745 | Antibacterial activity against Enterobacter aerogenes MTCC 39 assessed as inhibition zones at 100 ug/disk at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID456075 | Antibacterial activity against Bacillus cereus clinical isolate after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID311788 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 by microdilution technique | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | Minor sesquiterpene lactones from Centaurea pullata and their antimicrobial activity. |
| AID285159 | Antimicrobial activity against non replicating persistence Mycobacterium tuberculosis H37Rv in aerobic condition assessed by relative light units after 7 days | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. |
| AID633854 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID648387 | Antibacterial activity against Enterobacter aerogenes MTCC 111 at 10 ug/disc after 24 hrs by disc diffusion assay | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID544006 | Antimicrobial activity against Stenotrophomonas maltophilia isolate C422 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1179264 | Antimicrobial activity against Bacillus subtilis MTCC 441 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID528086 | Antibacterial activity against Bacillus subtilis ATCC 530 after 24 hrs by serial dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Efficient synthesis, spectral analysis and antimicrobial studies of nitrogen and sulfur containing spiro heterocycles from 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones. |
| AID294764 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 908 after 2 weeks by broth dilution method | 2007 | Bioorganic & medicinal chemistry letters, May-01, Volume: 17, Issue:9 | Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus. |
| AID278553 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium longum ATCC 15708 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID279878 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 31.3 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID289149 | Antimycobacterial activity against drug-sensitive Mycobacterium tuberculosis CIBIN 650 isolates | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines. |
| AID601250 | Antibacterial activity against Pseudomonas aeruginosa assessed as 99.5% bacterial killing using 1 x 10'4 CFU/ml inoculum after 72 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID326546 | Antimicrobial activity against Mycobacterium abscessus R61 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID544277 | Antimicrobial activity against Enterococcus faecalis NKH7 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID302004 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at MIC | 2007 | Bioorganic & medicinal chemistry, Dec-15, Volume: 15, Issue:24 | Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase. |
| AID293410 | Antibacterial activity against Escherichia coli ATCC 25922 by disc diffusion method | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis of some new bioactive 3-amino-2-mercapto-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one derivatives. |
| AID404901 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB41 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID440602 | Antibacterial activity against Bacillus thuringiensis assessed as zone of inhibition diameter at 1 mg/mL after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | Enaminonitrile in heterocyclic synthesis: synthesis and antimicrobial evaluation of some new pyrazole, isoxazole and pyrimidine derivatives incorporating a benzothiazole moiety. |
| AID494345 | Antibacterial activity against Bacillus subtilis by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization and antimicrobial studies of 2-(4-methoxy-phenyl)-5-methyl-4-(2-arylsulfanyl-ethyl)-2,4-dihydro-[1,2,4] triazolo-3-ones and their corresponding sulfones. |
| AID637033 | Antibacterial activity against Escherichia coli ATCC 8739 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID382571 | Antibacterial activity against Escherichia coli assessed as diameter of inhibition zone at 0.25% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID442431 | Antimicrobial activity against Listeria monocytogenes after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID341101 | Free Cmax in human at 1 g, iv | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID561101 | Antibacterial activity against Pasteurella multocida BB1035 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID440763 | Antibacterial activity against Pseudomonas aeruginosa assessed as zone of inhibition diameter at 1 mg/mL after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | Enaminonitrile in heterocyclic synthesis: synthesis and antimicrobial evaluation of some new pyrazole, isoxazole and pyrimidine derivatives incorporating a benzothiazole moiety. |
| AID1227452 | Antibacterial activity against Escherichia coli assessed as bacterial growth inhibition at 30 ug/ml after 24 hrs by cup-plate agar diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 25, Issue:1 | One-pot multicomponent synthesis of indole incorporated thiazolylcoumarins and their antibacterial, anticancer and DNA cleavage studies. |
| AID530528 | Induction of Ppbp2::lacZ gene expression in Staphylococcus aureus SH1000 at 3 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID326538 | Antimicrobial activity against Mycobacterium abscessus R39 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID283645 | Sensitivity of Escherichia coli K12 MG1655 in presence of 25 mM mannitol by disk diffusion method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID1476361 | Antitubercular activity against moxifloxacin resistant Mycobacterium tuberculosis H37Rv after 24 hrs by MABA method | 2017 | Journal of medicinal chemistry, 10-26, Volume: 60, Issue:20 | Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity. |
| AID464048 | Antibacterial activity against Micrococcus luteus clinical isolate after 48 hrs by serial dilution technique | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Sesquiterpene lactones from Anthemis melanolepis and their antibacterial and cytotoxic activities. Prediction of their pharmacokinetic profile. |
| AID774292 | Selectivity index, ratio of IC50 for african green monkey Vero cells to MIC90 for Mycobacterium tuberculosis H37Rv ATCC 27294 by microplate Alamar blue assay | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID104011 | Activity against Mycobacterium tuberculosis (H37Rv) using the standard BACTEC radiometric growth assay | 2000 | Journal of medicinal chemistry, Aug-24, Volume: 43, Issue:17 | A new class of antituberculosis agents. |
| AID456429 | Antibacterial activity against Shigella dysenteriae after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID1209456 | Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake | 2012 | Drug metabolism and disposition: the biological fate of chemicals, Jan, Volume: 40, Issue:1 | In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. |
| AID561111 | Antibacterial activity against Pasteurella multocida BB1045 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID625285 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic necrosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1546181 | Antimicrobial activity against Streptococcus lactis assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID326553 | Antimicrobial activity against Mycobacterium fortuitum V146 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID544287 | Antimicrobial activity against Enterococcus faecalis NKH17 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID424583 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH347 (SCV-19) harboring Arg659Ser mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID206033 | Tested for the antimicrobial activity as minimum inhibitory concentration against Staphylococcus epidermidis ATCC 12228 | 2002 | Bioorganic & medicinal chemistry letters, Mar-11, Volume: 12, Issue:5 | New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation. |
| AID523396 | Antimicrobial activity against amikacin-resistant Nocardia farcinica IFM 10580 after 3 days by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic. |
| AID1170646 | Antitubercular activity against Mycobacterium tuberculosis H37Rv by MABA assay | 2014 | Journal of natural products, Dec-26, Volume: 77, Issue:12 | Tetrahydroxanthene-1,3(2H)-dione derivatives from Uvaria valderramensis. |
| AID424602 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH351 (SCV-23) harboring -4 frameshift mutation at nucleotide 45-48 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1055963 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolate X004439 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1179285 | Antimicrobial activity against Salmonella paratyphi B after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID1156681 | Antimicrobial activity against Shigella flexneri MTCC 1457 assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID355494 | Antimicrobial activity against Mycobacterium smegmatis ATCC 607 after 48 hrs by twofold serial dilution method | |||
| AID1156887 | Antimicrobial activity against Bacillus subtilis NCIM 2250 after 24 hrs by NCCLS M7-A5 method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID144445 | In vitro antibacterial activity against Mycobacterium smegmatis 103599 | 1999 | Bioorganic & medicinal chemistry letters, Oct-18, Volume: 9, Issue:20 | New pyrrole derivatives as antimycobacterial agents analogs of BM212. |
| AID375852 | Antibacterial activity against Vibrio cholerae after 48 hrs by agar well diffusion method | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13 | Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes. |
| AID424617 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus AIS2006049 isolated from patients arm wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID449208 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv by twofold agar dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation. |
| AID774298 | Antimycobacterial activity against rifampin-resistant Mycobacterium tuberculosis ATCC 35838 | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID534337 | Antimicrobial activity against Burkholderia pseudomallei Bp216 harboring mini-Tn7T after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID625282 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID65071 | Estimated rate of [3H]DHS uptake in Escherichia coli K12 (ATCC 25868) | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID1546199 | Antimicrobial activity against Escherichia coli ATCC 25922 after 48 hrs by NCCLS protocol based method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID565752 | Antimicrobial activity against Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID617850 | Antitubercular activity against drug sensitive Mycobacterium tuberculosis H37Rv ATCC 27294 by microplate Alamar blue assay | 2011 | Journal of natural products, Sep-23, Volume: 74, Issue:9 | Stereochemical analysis of leubethanol, an anti-TB-active serrulatane, from Leucophyllum frutescens. |
| AID648389 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 at 10 ug/disc after 24 hrs by disc diffusion assay | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID1303882 | Antibacterial activity against multidrug resistant Staphylococcus aureus subsp. aureus Seattle 1945 (ATCC 25923) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID587850 | Antimicrobial activity against recombinant Mycobacterium ulcerans Mu1059 expressing luxAB from vibrio harveyi infected BALB/c mouse assessed as reduction in foodpad CFU count after 2 weeks relative to basal level | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Using bioluminescence to monitor treatment response in real time in mice with Mycobacterium ulcerans infection. |
| AID569260 | Antimicrobial activity against Staphylococcus aureus | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID770970 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 by broth dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Demonic axe-like conjugated alkynes in combating microbes. |
| AID477411 | Antibacterial activity against MBX-1090-resistant Staphylococcus aureus isolate d20A1 after 16 to 20 hrs by broth microdilution method | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID747763 | Antibacterial activity against Streptococcus faecalis | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID419829 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID382585 | Antibacterial activity against Pseudomonas aeruginosa assessed as diameter of inhibition zone at 2.0% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID1170143 | Antimicrobial activity against Escherichia coli DSM 1116 incubated for 24 hrs by disk diffusion method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Antibacterial secondary metabolites from an endophytic fungus, Eupenicillium sp. LG41. |
| AID1278998 | Antibacterial activity against Bacillus subtilis incubated for 20 hrs by microbroth dilution method | 2016 | Bioorganic & medicinal chemistry, Mar-15, Volume: 24, Issue:6 | Synthesis of fluorinated carbazoles via C-H arylation catalyzed by Pd/Cu bimetal system and their antibacterial activities. |
| AID603192 | Antibacterial activity against Escherichia coli MTCC 443 by broth microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 21, Issue:13 | Efficient synthesis, structural characterization and anti-microbial activity of chiral aryl boronate esters of 1,2-O-isopropylidene-α-D-xylofuranose. |
| AID1158050 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 7 days by serial dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla. |
| AID1156882 | Antimicrobial activity against Escherichia coli ATCC 25922 at 100 ug/disc after 24 hrs by agar cup plate method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID1241204 | Inhibition of pre-miR-21 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID424424 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus AIS2006032 isolated from patients foot wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID419830 | Antibacterial activity against Bacillus subtilis MTCC 619 after 24 hrs by liquid dilution method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID293411 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by disc diffusion method | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis of some new bioactive 3-amino-2-mercapto-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one derivatives. |
| AID563500 | Antimicrobial activity against Serratia marcescens ATCC 13880 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID277066 | Antibacterial activity against Staphylococcus aureus by measuring zone of inhibition at 30 ug after 24 hrs | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Synthesis of antimicrobial 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines. |
| AID278857 | Inhibition of metabolic activity in primary human osteoblasts assessed as MTT reduction after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID1456555 | Antibacterial activity against Staphylococcus aureus NCIM 5345 after 24 hrs by broth microdilution method | |||
| AID445331 | Cytotoxicity against human MRC5 cells | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID625287 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatomegaly | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID326541 | Antimicrobial activity against Mycobacterium abscessus R51 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID166712 | Tested for binding affinity against RNA construct A; n.b. means no observable binding | 2002 | Bioorganic & medicinal chemistry letters, Feb-11, Volume: 12, Issue:3 | Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers. |
| AID381181 | Antibacterial activity against Streptococcus faecalis after 24 to 72 hrs by disk diffusion method | 1999 | Journal of natural products, Sep, Volume: 62, Issue:9 | Antimicrobial and antitumor activities of mycosporulone. |
| AID633849 | Antibacterial activity against clinical isolate of Bacillus cereus after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID1171266 | Antimicrobial activity against Yersinia pseudotuberculosis YPIII PIB102-Elux by spectrophotometry | 2014 | Journal of natural products, Dec-26, Volume: 77, Issue:12 | Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems. |
| AID1463957 | Antimycobacterial activity MDR/XDR against Mycobacterium tuberculosis isolate Praha 4 incubated for 14 days by micromethod | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents. |
| AID1091739 | Antibacterial activity against Enterobacter aerogenes MTCC 39 assessed as growth arrest at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID278556 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium pseudolongum ATCC 25562 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1648090 | Antibacterial activity against Bacillus thuringiensis KACC 10168 assessed as reduction in microbial growth after 24 hrs by two-fold serial dilution method | 2020 | Journal of natural products, 02-28, Volume: 83, Issue:2 | Absolute Configuration and Antibiotic Activity of Piceamycin. |
| AID528089 | Antibacterial activity against Klebsiella pneumoniae ATCC 16425 after 24 hrs by serial dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Efficient synthesis, spectral analysis and antimicrobial studies of nitrogen and sulfur containing spiro heterocycles from 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones. |
| AID376324 | Antibacterial activity against Bacillus cereus isolate after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID648379 | Antibacterial activity against Salmonella Typhimurium MTCC 1251 after 24 hrs by two-fold serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID206640 | Minimum inhibitory concentration against Staphylococcus aureus (ATCC 6538) | 2001 | Bioorganic & medicinal chemistry letters, Mar-26, Volume: 11, Issue:6 | Structure elucidation and conformational properties of a novel bioactive clerodane diterpene using a combination of high field NMR spectroscopy, computational analysis and X-ray diffraction. |
| AID326537 | Antimicrobial activity against Mycobacterium abscessus R31 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID1274481 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by two-fold serial dilution method | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis and biological evaluation of novel phosphoramidate derivatives of coumarin as chitin synthase inhibitors and antifungal agents. |
| AID1191184 | Antibacterial activity against Bacillus subtilis | 2015 | European journal of medicinal chemistry, Jan-27, Volume: 90 | Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: the advances continue. |
| AID1091743 | Antibacterial activity against Bacillus subtilis MTCC 441 assessed as growth arrest at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID268911 | Antibacterial activity against Mycobacterium avium | 2006 | Journal of medicinal chemistry, Aug-10, Volume: 49, Issue:16 | Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity. |
| AID585432 | Antimicrobial activity against oqxAB positive Escherichia coli DH5[alpha] harboring pMD18-T::oqxAB by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1303895 | Antibacterial activity against multidrug resistant Pseudomonas aeruginosa NCTC 10332 (ATCC 10145) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID1546186 | Antimicrobial activity against Pseudomonas assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID456356 | Antibacterial activity against Escherichia coli NCIB 86 after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID1233488 | Antimicrobial activity against Enterobacter aerogenes MTCC 111 assessed as inhibition of visual microbial growth incubated for 24 hrs at 37 degC | 2015 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 25, Issue:14 | Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. |
| AID382579 | Antibacterial activity against Escherichia coli assessed as diameter of inhibition zone at 1.0% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID1055935 | Antimycobacterial activity against Mycobacterium tuberculosis harboring luxABCDE under hypoxic condition after 10 days by MABA assay in presence of 10% fetal bovine serum | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID428873 | Antibacterial activity against Escherichia coli JM109 carrying pMCL210 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID1255676 | Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 to 48 hrs | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID1055954 | Antimycobacterial activity against capreomycin-resistant Mycobacterium tuberculosis under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID562382 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID279866 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 250 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID534338 | Antimicrobial activity against Burkholderia pseudomallei Bp250 harboring mini-Tn7T-bpeA+B+ -oprB+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID562813 | Antimicrobial activity against Escherichia coli DH5[alpha] harboring pEK516 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID562590 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID600679 | Bactericidal activity against Staphylococcus aureus ATCC 6538 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1600165 | Antifungal activity against Rhodotorula glutinis NCIM 3168 assessed as zone of inhibition at 80 ug/well incubated for 48 to 72 hrs by by agar well diffusion method | 2019 | European journal of medicinal chemistry, Oct-01, Volume: 179 | Synthesis of new thiazolyl-pyrazolyl-1,2,3-triazole derivatives as potential antimicrobial agents. |
| AID144296 | In vitro antibacterial activity against Mycobacterium marinum 6423 | 1999 | Bioorganic & medicinal chemistry letters, Oct-18, Volume: 9, Issue:20 | New pyrrole derivatives as antimycobacterial agents analogs of BM212. |
| AID565748 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1600167 | Antifungal activity against Candida albicans NCIM 3100 assessed as zone of inhibition at 80 ug/well incubated for 48 to 72 hrs by by agar well diffusion method | 2019 | European journal of medicinal chemistry, Oct-01, Volume: 179 | Synthesis of new thiazolyl-pyrazolyl-1,2,3-triazole derivatives as potential antimicrobial agents. |
| AID326549 | Antimicrobial activity against Mycobacterium abscessus R49 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID1072955 | Reduction in intracellular dipeptide D-alanyl-D-alanine pool size in Mycobacterium tuberculosis H37Rv up to 5 times MIC by filter-based mass spectrometry technique | 2013 | ACS medicinal chemistry letters, Dec-12, Volume: 4, Issue:12 | Metabolomics Reveal d-Alanine:d-Alanine Ligase As the Target of d-Cycloserine in |
| AID733714 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 at 1 mg/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID774838 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 0.5 to 1 mg/ml at 37 degC after 18 hrs by well plate method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis, characterization and molecular docking studies of some new 1,3,4-oxadiazolines bearing 6-methylpyridine moiety for antimicrobial property. |
| AID644173 | Antibacterial activity against Bacillus cereus clinical isolate treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID65059 | Concentration required for half maximum rate of enhanced [3H]DHS uptake in Escherichia coli K12 | 1987 | Journal of medicinal chemistry, Feb, Volume: 30, Issue:2 | Comparison of aminoglycoside antibiotics with respect to uptake and lethal activity in Escherichia coli. |
| AID294740 | Antibacterial activity against Salmonella typhi at 0.125% (w/v) concentration after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID719451 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 500 ug/mL after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core. |
| AID565231 | Antimicrobial activity against Mycobacterium chelonae 9917 harboring pZS01 carrying mspA gene by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID637030 | Antibacterial activity against Staphylococcus aureus NRRL B 313 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID601601 | Antibacterial activity against Brevundimonas sp. isolate Fs30 at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID1105401 | Antibacterial activity against Bacillus pumilus MTCC 2466 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID311349 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by MTT assay | 2007 | Journal of natural products, Sep, Volume: 70, Issue:9 | Targeted natural product isolation guided by HPLC-SPE-NMR: constituents of Hubertia species. |
| AID71055 | Compound was tested for photoinhibition of Escherichia coli (CIP 548T); Sensitive | 1998 | Bioorganic & medicinal chemistry letters, Nov-03, Volume: 8, Issue:21 | Nitroglycosylated meso-arylporphyrins as photoinhibitors of gram positive bacteria. |
| AID678625 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 50 mg/ml after 24 hrs by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of optically active conjugated γ- and δ-lactone derivatives. |
| AID1597390 | Antimicrobial activity against Bacillus cereus MTCC 8558 incubated for 24 hrs by well diffusion method | 2019 | European journal of medicinal chemistry, Sep-01, Volume: 177 | Synthesis, biological evaluation and computational study of novel isoniazid containing 4H-Pyrimido[2,1-b]benzothiazoles derivatives. |
| AID285162 | Antimicrobial activity against non replicating persistence Mycobacterium tuberculosis H37Rv in anaerobic condition assessed as bacterial density after 10 days | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. |
| AID1224525 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 4 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID376311 | Antibacterial activity against Staphylococcus aureus assessed as total inhibition of cell growth/spore germination after 24 hrs | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Antimicrobial dialkylresorcinols from Pseudomonas sp. Ki19. |
| AID565746 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID611680 | Antifungal activity against Septoria tritici at 0.05 mg by agar diffusion method | 2011 | Journal of natural products, Jul-22, Volume: 74, Issue:7 | Bioactive 11,20-epoxy-3,5(16)-diene briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. |
| AID419573 | Antibacterial activity against Pseudomonas putida MTCC 121 at 50 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID585430 | Antimicrobial activity against oqxAB positive Escherichia coli C600 SP8-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1600168 | Antibacterial activity against Staphylococcus albus NCIM 2178 assessed as zone of inhibition at 80 ug/well incubated for 24 to 48 hrs by by agar well diffusion method | 2019 | European journal of medicinal chemistry, Oct-01, Volume: 179 | Synthesis of new thiazolyl-pyrazolyl-1,2,3-triazole derivatives as potential antimicrobial agents. |
| AID530253 | Antimicrobial activity against dnaJ deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 10 ug/ml after 3 hrs by time kill analysis | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID615477 | Antimicrobial activity against Escherichia coli at 100 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID1114817 | Antibacterial activity against Mycobacterium smegmatis ATCC 607 after 48 to 72 hr by double microdilution method | 2013 | Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, Aug, Volume: 22, Issue:8 | |
| AID440766 | Antibacterial activity against Bacillus subtilis after 24-48 hrs by microdilution susceptibility test | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | Enaminonitrile in heterocyclic synthesis: synthesis and antimicrobial evaluation of some new pyrazole, isoxazole and pyrimidine derivatives incorporating a benzothiazole moiety. |
| AID279901 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 62.5 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID283651 | Antibacterial activity against Escherichia coli K12 DH5alpha | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID625447 | Antimicrobial activity against Staphylococcus epidermidis by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Iodine-catalyzed conjugate addition of indoles onto en-1,4-dione: a novel synthesis of 3-(1-(1H-indol-3-yl)-2-oxo-2-phenylethyl)indolin-2-ones as antibacterial and antifungal agents. |
| AID625280 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID540928 | Antimicrobial activity against streptomycin-resistant Streptomyces coelicolor KO-178 harboring rpsL K88E mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID329352 | Antimicrobial activity against Yersinia pestis KIM6-2082.1+ in presence of iron limiting PMH-D medium | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID644166 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1159124 | Antimicrobial activity against Bacillus thuringiensis for 24 hrs by microdillution method | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID586086 | Antimicrobial activity against verocytotoxin-producing Escherichia coli isolate O157 obtained from animals and food assessed as percentage of resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID603193 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 by broth microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 21, Issue:13 | Efficient synthesis, structural characterization and anti-microbial activity of chiral aryl boronate esters of 1,2-O-isopropylidene-α-D-xylofuranose. |
| AID293412 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by disc diffusion method | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis of some new bioactive 3-amino-2-mercapto-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one derivatives. |
| AID562387 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1600169 | Antifungal activity against Aspergillus niger NCIM 504 assessed as zone of inhibition at 80 ug/well incubated for 48 to 72 hrs by by agar well diffusion method | 2019 | European journal of medicinal chemistry, Oct-01, Volume: 179 | Synthesis of new thiazolyl-pyrazolyl-1,2,3-triazole derivatives as potential antimicrobial agents. |
| AID633857 | Antibacterial activity against clinical isolate of Bacillus cereus incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID326533 | Antimicrobial activity against Mycobacterium abscessus after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID1555430 | Antibacterial activity against Pseudomonas aeruginosa assessed as diameter of zone of inhibition at 10 ug/disc by disc diffusion method | 2019 | European journal of medicinal chemistry, Aug-15, Volume: 176 | Phytochemical and pharmacological attributes of piperine: A bioactive ingredient of black pepper. |
| AID1542737 | Antibacterial activity against Staphylococcus intermedius 1051997 measured after 18 hrs by broth dilution method | 2019 | Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10 | 6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers. |
| AID278987 | Antimycobacterial activity in Mycobacterium ulcerans Cu001 infected BALB/c mouse assessed as mean number of CFU per foot-pad at 150 mg, sc after 2 weeks | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Curing Mycobacterium ulcerans infection in mice with a combination of rifampin-streptomycin or rifampin-amikacin. |
| AID648376 | Antibacterial activity against Enterobacter aerogenes MTCC 111 after 24 hrs by twofold serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID144013 | Antibacterial activity was evaluated against Mycobacterium fortuitum. | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID283655 | Effect on sensitivity of Escherichia coli K12 MG1655 with sodA, sodB, or sodC genes assessed as alteration in susceptibility | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID373986 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr expressing Escherichia coli J53 qnrA1 bearing pHS3 transconjugant from Citrobacter freundii 64 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID278548 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium bifidum BB12 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID617851 | Antitubercular activity against multidrug-resistant Mycobacterium tuberculosis CIBIN/UMF15:99 isolate by microplate Alamar blue assay | 2011 | Journal of natural products, Sep-23, Volume: 74, Issue:9 | Stereochemical analysis of leubethanol, an anti-TB-active serrulatane, from Leucophyllum frutescens. |
| AID446149 | Antimycobacterial activity against streptomycin-resistant Mycobacterium tuberculosis H37Rv after 16 to 24 hrs by microplate alamar | 2010 | Journal of medicinal chemistry, Jan-28, Volume: 53, Issue:2 | Rational design of 5-phenyl-3-isoxazolecarboxylic acid ethyl esters as growth inhibitors of Mycobacterium tuberculosis. a potent and selective series for further drug development. |
| AID530537 | Induction of PvraSr::lacZ gene expression in Staphylococcus aureus SH1000 at 3 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID326535 | Antimicrobial activity against Mycobacterium fortuitum after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID1255673 | Antibacterial activity against Escherichia coli ATCC 8739 after 24 to 48 hrs | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID572150 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBAD plasmid after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID279865 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 500 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID424603 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH360 (SCV-32) harboring ATA start codon at nucleotide 3 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID625373 | Antibacterial activity against Bacillus subtilis ATCC 451 after 24 hrs by twofold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Synthesis, stereochemistry and in vitro antimicrobial evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-4-phenyl-2,3-dihydrothiazoles. |
| AID145132 | In vitro antibacterial activity against Mycobacterium tuberculosis 103471 | 1999 | Bioorganic & medicinal chemistry letters, Oct-18, Volume: 9, Issue:20 | New pyrrole derivatives as antimycobacterial agents analogs of BM212. |
| AID338745 | Antimicrobial activity against Bacillus subtilis after 24 hrs by twofold serial broth dilution technique | |||
| AID737336 | Antimicrobial activity against Staphylococcus aureus ATCC 29513 at 750 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID442425 | Antimicrobial activity against Micrococcus flavus after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID341094 | Antimicrobial activity against antibiotic-resistant Yersinia pestis mutant on day 6 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID626283 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 1 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID534425 | Antibacterial activity against Mycobacterium bovis BCG-Glaxo | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics. |
| AID426315 | Antimycobacterial activity against Mycobacterium tuberculosis H37Ra after 24 hrs by microplate alamar Blue assay | 2009 | Journal of natural products, Jun, Volume: 72, Issue:6 | Cytotoxic and antimycobacterial prenylated flavonoids from the roots of Eriosema chinense. |
| AID1245993 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID565745 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecium clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID278534 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium animalis ATCC 27536 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID515232 | Antibacterial activity against Bacillus subtilis at 50 ug/ml after 18 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Anti-tubercular agents. Part 5: synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners. |
| AID326543 | Antimicrobial activity against Mycobacterium abscessus R47 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID1296385 | Antimycobacterial activity against multi drug resistant Mycobacterium tuberculosis 8666/2010 after 14 days by microdilution method | 2016 | Journal of medicinal chemistry, Mar-24, Volume: 59, Issue:6 | Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. |
| AID144295 | Antimycobacterial activity against Mycobacterium marinum CIP 6423 | 1998 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 8, Issue:20 | Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis. |
| AID279897 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 1000 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID279868 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 62.5 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID733698 | Antibacterial activity against methicillin-resistant Staphylococcus aureus after 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID585421 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W322-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1477417 | Antibacterial activity against 6-((3-Fluorobenzyl)(methyl)amino)-N-(4-methoxyphenyl)-pyrimidine-4-carboxamide-resisitant Mycobacterium tuberculosis H37Rv grown in GAST/Fe medium measured on day 14 post inoculation by broth microdilution method | 2017 | Journal of medicinal chemistry, 12-28, Volume: 60, Issue:24 | Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies. |
| AID341092 | Antimicrobial activity against antibiotic-resistant Yersinia pestis mutant in human serum assessed as decrease in bacterial population after 12 hrs | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID562594 | Antimicrobial activity against vancomycin-nonsusceptible Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID696344 | Antibacterial activity against Bacillus subtilis ATCC 530 after 24 hrs by two fold serial dilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 22, Issue:21 | Design, synthesis, spectral and biological evaluation of novel 1-allyl substituted 2,6-diphenylpiperidin-4-ones and its derivatives of oximes/oxime ethers. |
| AID574593 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 2403 obtained from sputum of patient at 1 ug/ml by Bactec MGIT960 modified proportion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID515920 | Antibacterial activity against kanamycin-resistant Mycobacterium tuberculosis after 7 days by microplate alamar blue assay | 2010 | Bioorganic & medicinal chemistry, Oct-15, Volume: 18, Issue:20 | Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring. |
| AID620349 | Antibacterial activity against Escherichia coli RCMB 000103 at 30 ug/ml after 24 hrs by diffusion agar technique | 2011 | European journal of medicinal chemistry, Oct, Volume: 46, Issue:10 | Synthesis and anti-microbial activity of some 1- substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives. |
| AID535769 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID1546651 | Antibacterial activity against Klebsiella pneumoniae MTCC 618 assessed as reduction in microbial growth after 24 hrs by CLSI based microdilution method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID544007 | Antimicrobial activity against Bacillus sphaericus isolate C237 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID228036 | Percent of interaction with wheat germ tRNA (type V) at a concentration of 35 uM | 2001 | Bioorganic & medicinal chemistry letters, Apr-23, Volume: 11, Issue:8 | Study of aminoglycoside-nucleic acid interactions by an HPLC method. |
| AID1594069 | Antibacterial activity against Staphylococcus aureus assessed as reduction in bacterial cell viability incubated for 20 to 24 hrs by REMA method | 2019 | Bioorganic & medicinal chemistry, 06-15, Volume: 27, Issue:12 | Design, synthesis, in-silico studies and biological screening of quinazolinone analogues as potential antibacterial agents against MRSA. |
| AID477423 | Selectivity ratio of MIC for MBX-1090-resistant Staphylococcus aureus isolate d20A1 to MIC for Staphylococcus aureus NCTC 8325 | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR. |
| AID540929 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor KO-347 harboring rpsl P91S mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID370073 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 35820 after 14 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID523405 | Antimicrobial activity against amikacin-susceptible Nocardia farcinica IFM 10152 after 3 days by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Homozygous triplicate mutations in three 16S rRNA genes responsible for high-level aminoglycoside resistance in Nocardia farcinica clinical isolates from a Canada-wide bovine mastitis epizootic. |
| AID574587 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 761 obtained from pus of patient at 1 ug/ml by Bactec MGIT960 modified proportion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID278544 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium thermophilum ATCC 25866 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID608673 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as zone of inhibition at 500 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID1279000 | Antibacterial activity against Escherichia coli incubated for 20 hrs by microbroth dilution method | 2016 | Bioorganic & medicinal chemistry, Mar-15, Volume: 24, Issue:6 | Synthesis of fluorinated carbazoles via C-H arylation catalyzed by Pd/Cu bimetal system and their antibacterial activities. |
| AID665395 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by serial dilution technique | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Synthesis, characterization, antimicrobial activities and QSAR studies of some 10a-phenylbenzo[b]indeno[1,2-e][1,4]thiazin-11(10aH)-ones. |
| AID1546188 | Antifungal activity against Aspergillus niger assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID600671 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID279565 | Antimicrobial activity against Salmonella enterica serovar Typhimurium JB127 in Caenorhabditis elegans | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium. |
| AID1255666 | Antibacterial activity against Escherichia coli ATCC 8739 assessed as growth inhibition at 100 ug/ml after 8 to 24 hrs by agar well diffusion method | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID442426 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID424825 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH292 harboring Gly664Val mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1191876 | Antimicrobial activity against isoniazid and rifampin resistant Mycobacterium tuberculosis after 21 days at 37 degC by agar dilution drug susceptibility assay | 2015 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 25, Issue:6 | A novel molecule with notable activity against multi-drug resistant tuberculosis. |
| AID544026 | Antimicrobial activity against Acinetobacter lwoffii isolate C37 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID217188 | In vitro cytotoxicity against VERO cells. | 1998 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 8, Issue:20 | Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis. |
| AID600725 | Antibacterial activity against Pseudomonas fluorescens at 10 ug/disc after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Urea/thiourea derivatives of quinazolinone-lysine conjugates: synthesis and structure-activity relationships of a new series of antimicrobials. |
| AID544023 | Antimicrobial activity against Psychrobacter ikaite isolate C713 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID294765 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 910 after 2 weeks by broth dilution method | 2007 | Bioorganic & medicinal chemistry letters, May-01, Volume: 17, Issue:9 | Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus. |
| AID456083 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1272622 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis after 21 days by broth microdilution method | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. |
| AID279879 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 15.6 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID528088 | Antibacterial activity against Escherichia coli ATCC 26032 after 24 hrs by serial dilution method | 2010 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 20, Issue:22 | Efficient synthesis, spectral analysis and antimicrobial studies of nitrogen and sulfur containing spiro heterocycles from 2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ones. |
| AID537114 | Cytotoxicity against mouse J774A1 cells after 24 to 72 hrs by MTT assay | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22 | Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin. |
| AID442417 | Antimicrobial activity against Micrococcus flavus at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID424342 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH187 harboring His457Tyr mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID673185 | Antimicrobial activity against Bacillus subtilis MTCC 441 after 24 hrs by agar well diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 22, Issue:15 | Synthesis and biological evaluation of novel 2,4,6-triazine derivatives as antimicrobial agents. |
| AID674381 | Antibacterial activity Escherichia coli ATCC 25922 at 0.5 mg/ml after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: as a new class of potent antioxidants and antimicrobials--a novel accost to amend biocompatibility. |
| AID1156680 | Antimicrobial activity against Proteus vulgaris MTCC 1771 assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID1511407 | Antibacterial activity against Pseudomonas aeruginosa assessed as reduction in bacterial cell growth incubated for 24 hrs by filter paper assay | 2019 | Bioorganic & medicinal chemistry, 11-01, Volume: 27, Issue:21 | Synthesis and biological evaluation of calycanthaceous alkaloid analogs. |
| AID540212 | Mean residence time in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID1183528 | Antibacterial activity against Bacillus subtilis MTCC-441 assessed as zone of inhibition at 10 ug/disc | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties. |
| AID1278999 | Antibacterial activity against Staphylococcus aureus incubated for 20 hrs by microbroth dilution method | 2016 | Bioorganic & medicinal chemistry, Mar-15, Volume: 24, Issue:6 | Synthesis of fluorinated carbazoles via C-H arylation catalyzed by Pd/Cu bimetal system and their antibacterial activities. |
| AID1183526 | Antibacterial activity against Staphylococcus aureus MTCC-7443 assessed as zone of inhibition at 10 ug/disc | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Synthesis of novel thiadiazolotriazin-4-ones and study of their mosquito-larvicidal and antibacterial properties. |
| AID568757 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 25177 at 10 ug after 12 days by disc diffusion assay | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | Pitiprolamide, a proline-rich dolastatin 16 analogue from the marine cyanobacterium Lyngbya majuscula from Guam. |
| AID694357 | Antibacterial activity against Mycobacterium tuberculosis H37Rv under anaerobic condition assessed as growth inhibition at 0.1 ug/ml by BACTEC method | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. |
| AID560899 | Antibacterial activity against cefoxitin-resistant Escherichia coli by microdilution method | 2009 | Antimicrobial agents and chemotherapy, Jul, Volume: 53, Issue:7 | Characterization of cefoxitin-resistant Escherichia coli isolates from recreational beaches and private drinking water in Canada between 2004 and 2006. |
| AID375848 | Antibacterial activity against Staphylococcus aureus after 48 hrs by agar well diffusion method | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13 | Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes. |
| AID1224519 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 9449/2007 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID1247077 | Antibacterial activity against Salmonella typhimurium assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID515238 | Antibacterial activity against Klebsiella pneumoniae at 50 ug/ml after 18 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Anti-tubercular agents. Part 5: synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners. |
| AID311348 | Antimicrobial activity against Escherichia coli ATCC 11229 after 24 hrs by MTT assay | 2007 | Journal of natural products, Sep, Volume: 70, Issue:9 | Targeted natural product isolation guided by HPLC-SPE-NMR: constituents of Hubertia species. |
| AID419570 | Antibacterial activity against Escherichia coli MTCC 51 at 50 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID1262005 | Antitubercular activity against Mycobacterium tuberculosis H37Rv after 5 days by microplate Alamar blue assay | 2015 | European journal of medicinal chemistry, Nov-13, Volume: 105 | A click chemistry approach for the synthesis of mono and bis aryloxy linked coumarinyl triazoles as anti-tubercular agents. |
| AID1075578 | Antimicrobial activity against Micrococcus luteus NRLL B-4375 after 18 to 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents. |
| AID283646 | Susceptibility of Escherichia coli K12 MG1655 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID534344 | Antimicrobial activity against Burkholderia pseudomallei Bp174 harboring mini-Tn7T-bpeR+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID424824 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH296 harboring Gly664Ala mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID600678 | Antibacterial activity against Enterococcus faecalis isolate obtained from human after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID614918 | Antibacterial activity against Escherichia coli ATCC 8739 after 24 hrs by broth micro dilution assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis, antimicrobial evaluation and QSAR analysis of novel nalidixic acid based 1,2,4-triazole derivatives. |
| AID424604 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH383 (SCV-55) harboring TAA stop codon at nucleotide 139 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1171264 | Inhibition of YopE in Yersinia pseudotuberculosis YPIII PIB102-Elux measured after 3 hrs 15 mins by luminescent reporter-gene assay | 2014 | Journal of natural products, Dec-26, Volume: 77, Issue:12 | Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems. |
| AID442416 | Antimicrobial activity against Bacillus cereus at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1193496 | Thermodynamic equilibrium solubility, log S of the compound in water at RT after 24 hrs by shake-flask method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. |
| AID637080 | Antibacterial activity against Bacillus mycoides DSMZ 274 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1061249 | Antimicrobial activity against Bacillus subtilis at 0.5 mg/ml by well plate method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Synthesis and biological evaluation of novel substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1-b] [1,3,4] thiadiazole derivatives. |
| AID574810 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 2911 horboring rpoB D516V, katG S315T/R463L, gyrA D94G/S95T/R128S/Y129C, rrs A1401G by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID424612 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH294 harboring Gly628Val mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1055961 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolate X005319 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1055953 | Antimycobacterial activity against Mycobacterium smegmatis ATCC 700084 under normoxic condition after 72 hrs by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1179572 | Antibacterial activity against methicillin-resistant Staphylococcus aureus by NCCLS method | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives. |
| AID375849 | Antibacterial activity against Pseudomonas aeruginosa after 48 hrs by agar well diffusion method | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13 | Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes. |
| AID1245991 | Antimicrobial activity against Pseudomonas syringae pv. actinidiae 16027 after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID424422 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus HIP15178 isolated from patients surgical wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID594328 | Antimicrobial activity against Staphylococcus aureus NCIM 2079/ATCC 6538P at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID145022 | Antimycobacterial activity against Mycobacterium tuberculosis CIP 103471 | 1998 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 8, Issue:20 | Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis. |
| AID770974 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Demonic axe-like conjugated alkynes in combating microbes. |
| AID1104315 | Antibacterial activity against clinical isolate Bacillus cereus at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1179570 | Antibacterial activity against Pseudomonas aeruginosa MTCC 201 at 100 ug/well after 24 hrs by well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives. |
| AID414461 | Antitubercular activity against isoniazid-resistant Mycobacterium tuberculosis H37Rv ATCC 27294 after 7 days by microplate alamar blue assay | 2009 | Journal of medicinal chemistry, Apr-09, Volume: 52, Issue:7 | Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium tuberculosis. |
| AID1454341 | Antibacterial activity Staphylococcus aureus MTCC 96 by agar well method | 2017 | Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15 | Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides. |
| AID456431 | Antifungal activity against Candida albicans after 3 days by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID562809 | Antimicrobial activity against Escherichia coli J53 | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID382584 | Antibacterial activity against Staphylococcus aureus assessed as diameter of inhibition zone at 2.0% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID561099 | Antibacterial activity against Pasteurella multocida ATCC 43137 by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID278533 | Antimicrobial activity against Bifidobacterium breve R0070 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1168605 | Antibacterial activity against Escherichia coli at 50 ug/mL incubated for 24 hrs by agar well diffusion method | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets. |
| AID1156687 | Antimicrobial activity against Micrococcus luteus MTCC 106 assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID442429 | Antimicrobial activity against Enterobacter cloacae after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1055967 | Antimycobacterial activity against Mycobacterium tuberculosis harboring luxABCDE under hypoxic condition after 10 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID689077 | Antibacterial activity against Bacillus megaterium assessed as zone of inhibition at 0.05 mg by agar diffusion method | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Sinularosides A and B, bioactive 9,11-secosteroidal glycosides from the South China Sea soft coral Sinularia humilis Ofwegen. |
| AID1274480 | Antibacterial activity against Proteus vulgaris ATCC 8427 after 24 hrs by two-fold serial dilution method | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis and biological evaluation of novel phosphoramidate derivatives of coumarin as chitin synthase inhibitors and antifungal agents. |
| AID532982 | Antibacterial activity against Escherichia coli W3110 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID665398 | Antibacterial activity against Pseudomonas aeruginosa MTCC 7952 after 24 hrs by serial dilution technique | 2012 | European journal of medicinal chemistry, Jul, Volume: 53 | Synthesis, characterization, antimicrobial activities and QSAR studies of some 10a-phenylbenzo[b]indeno[1,2-e][1,4]thiazin-11(10aH)-ones. |
| AID1303881 | Antibacterial activity against multidrug resistant Enterococcus faecium NCTC 7171 (ATCC 19434) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID1083211 | Bactericidal activity against Erwinia amylovora 295/93 assessed as growth inhibition in King's B full medium measured at pH 7.2 after overnight incubation by suspension culture assay | 2012 | Journal of agricultural and food chemistry, Dec-12, Volume: 60, Issue:49 | Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora. |
| AID608667 | Antibacterial activity against Bacillus subtilis assessed as zone of inhibition at 500 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID1286940 | Antibacterial activity against Escherichia coli MTCC 443 by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 26, Issue:6 | Indole-2-carboxylic acid derived mono and bis 1,4-disubstituted 1,2,3-triazoles: Synthesis, characterization and evaluation of anticancer, antibacterial, and DNA-cleavage activities. |
| AID294763 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 906 after 2 weeks by broth dilution method | 2007 | Bioorganic & medicinal chemistry letters, May-01, Volume: 17, Issue:9 | Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus. |
| AID1193498 | Thermodynamic equilibrium solubility, log S of the compound simulated gastric fluid at pH 1.2 at RT after 24 hrs by shake-flask method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. |
| AID424591 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH333 (SCV-5) harboring TAA stop codon at nucleotide 249 in rplF but gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID719313 | Antimicrobial activity against Escherichia coli NCIM 2574 at 10 ug/disc incubated for 24 hrs by agar disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID520108 | Antimicrobial activity against Mycobacterium tuberculosis H37Rv at assessed as growth inhibition at 10 mg/kg following 24 days oxygen depletion by Wayne method relative to control | 2008 | Antimicrobial agents and chemotherapy, Apr, Volume: 52, Issue:4 | Evaluation of a 2-pyridone, KRQ-10018, against Mycobacterium tuberculosis in vitro and in vivo. |
| AID614916 | Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 24 hrs by broth micro dilution assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis, antimicrobial evaluation and QSAR analysis of novel nalidixic acid based 1,2,4-triazole derivatives. |
| AID245125 | In vitro minimum inhibitory concentration against vancomycin-resistant Enterococcus faecalis NCTC 12201 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2 | Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones. |
| AID419828 | Antibacterial activity against Escherichia coli MTCC 722 at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID1454339 | Antibacterial activity Klebsiella pneumoniae MTCC 618 by agar well method | 2017 | Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15 | Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides. |
| AID1546187 | Antimicrobial activity against Streptomyces assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID278543 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium pseudolongum ATCC 25562 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID442414 | Antimicrobial activity against Salmonella Typhimurium at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID530249 | Antimicrobial activity against ygfA deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 10 ug/ml after 3 hrs by time kill analysis relative to wild type | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID747755 | Antibacterial activity against Klebsiella pneumoniae | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID1186778 | Antibacterial activity against Streptococcus pyogenes MTCC 1926 after 24 hrs by agar well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17 | Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: synthesis, characterization and evaluation of anticancer and antimicrobial activities. |
| AID326534 | Antimicrobial activity against Mycobacterium chelonae after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID562811 | Antimicrobial activity against Escherichia coli J53 harboring pEK204 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID544274 | Antimicrobial activity against Enterococcus faecalis NKH4 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID562239 | Antimycobacterial activity against Mycobacterium smegmatis by GFP-based fluorescence assay | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Modifying culture conditions in chemical library screening identifies alternative inhibitors of mycobacteria. |
| AID625292 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) combined score | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID644177 | Antibacterial activity against Enterobacter cloacae human isolate treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID614920 | Antibacterial activity against Staphylococcus aureus ATCC 2937 after 24 hrs by broth micro dilution assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis, antimicrobial evaluation and QSAR analysis of novel nalidixic acid based 1,2,4-triazole derivatives. |
| AID1272621 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis after 14 days by broth microdilution method | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. |
| AID656230 | Antimycobacterial activity against isoniazid-, rifampin-, streptomycin-, ethambutol-resistant Mycobacterium tuberculosis after 16 to 24 hrs by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. |
| AID1174106 | Antimycobacterial activity against isoniazid, rifampin, ethambutol, streptomycin, ofloxacin-resistant Mycobacterium tuberculosis after 7 days by microplate Alamar blue assay | 2015 | European journal of medicinal chemistry, Jan-07, Volume: 89 | Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis. |
| AID594273 | Antimicrobial activity against Bacillus subtilis NCIM 2063/ATCC 6633 at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID625286 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatitis | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID278557 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium thermophilum ATCC 25866 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1296387 | Antimycobacterial activity against multi drug resistant Mycobacterium tuberculosis Praha 4 after 14 days by microdilution method | 2016 | Journal of medicinal chemistry, Mar-24, Volume: 59, Issue:6 | Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. |
| AID200709 | Antibacterial activity against gram negative bacteria Salmonella Typhimurium was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID1156691 | Antimicrobial activity against Proteus vulgaris MTCC 1771 assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID648384 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 10 ug/disc after 24 hrs by disc diffusion assay | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID490976 | Antibacterial activity against Escherichia coli ATCC 25922 after 48 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach. |
| AID594335 | Antimicrobial activity against Escherichia coli NCIM 2068/ATCC 11105 at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID674383 | Antibacterial activity Pseudomonas aeruginosa ATCC 27853 at 0.5 mg/ml after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: as a new class of potent antioxidants and antimicrobials--a novel accost to amend biocompatibility. |
| AID326540 | Antimicrobial activity against Mycobacterium abscessus NTU459 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID278522 | Antimicrobial activity against Bifidobacterium bifidum R0071 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID637024 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID424423 | Antibacterial activity against Enterococcus faecalis HIP15179 coisolated with vancomycin-resistant Staphylococcus aureus by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID534422 | Antibacterial activity against Mycobacterium bovis BCG-japan | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics. |
| AID633858 | Antibacterial activity against Micrococcus flavus ATCC 10240 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID424346 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH193 harboring TAA stop codon at nucleotide 299 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID278550 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium breve R0070 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1071640 | Antimicrobial activity against Mycobacterium phlei after 5 days by microplate Alamar Blue assay | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis, structure-activity relationship of iodinated-4-aryloxymethyl-coumarins as potential anti-cancer and anti-mycobacterial agents. |
| AID1596675 | Bactericidal activity against Listeria monocytogenes NCTC 7973 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID278856 | Antiproliferative effect against primary human osteoblasts assessed as BrdU incorporation into DNA after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID582764 | Antimicrobial activity against eaeA negative verocytotoxin-producing non-O157 Escherichia coli isolates obtained from human assessed as percentage of resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID442415 | Antimicrobial activity against Listeria monocytogenes at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID244839 | Minimum inhibitory concentration against Bacillus subtilis | 2005 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 15, Issue:7 | Enhancement in antimicrobial activity of 2-(phenyl)-3-(2-butyl-4-chloro-1H-imidazolyl)-5-butylate isoxazolidine. |
| AID424576 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH334 (SCV-6) harboring Thr436Ile mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1168606 | Antibacterial activity against Escherichia coli incubated for 24 hrs by agar microdilution method | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets. |
| AID294736 | Antibacterial activity against Aeromonas hydrophila at 0.5% (w/v) concentration after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID277067 | Antibacterial activity against Bacillus subtilis by measuring zone of inhibition at 30 ug after 24 hrs | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Synthesis of antimicrobial 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines. |
| AID278562 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium breve R0070 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID541819 | Antibacterial activity against Bacillus subtilis RIK543 after 15 hrs | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Inactivation of KsgA, a 16S rRNA methyltransferase, causes vigorous emergence of mutants with high-level kasugamycin resistance. |
| AID279899 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 250 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID562384 | Antimicrobial activity against Enterococcus faecium clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1071641 | Antimicrobial activity against Mycobacterium tuberculosis H37Rv after 5 days by microplate Alamar Blue assay | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis, structure-activity relationship of iodinated-4-aryloxymethyl-coumarins as potential anti-cancer and anti-mycobacterial agents. |
| AID294969 | Antifungal activity against Candida glabrata after 48 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID600724 | Antibacterial activity against Escherichia coli at 10 ug/disc after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Urea/thiourea derivatives of quinazolinone-lysine conjugates: synthesis and structure-activity relationships of a new series of antimicrobials. |
| AID568758 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 25177 at 5 ug after 12 days by disc diffusion assay | 2011 | Journal of natural products, Jan-28, Volume: 74, Issue:1 | Pitiprolamide, a proline-rich dolastatin 16 analogue from the marine cyanobacterium Lyngbya majuscula from Guam. |
| AID631061 | Ratio of MIC90 for Yersinia pestis KIM6-2082.1+ in PMHD medium supplemented with 100 uM FeCl3 to IC50 for Yersinia pestis KIM6-2082.1+ in Fe-deficient PMHD medium | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID490982 | Antifungal activity against Aspergillus niger NCIM 545 after 24 to 72 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach. |
| AID1596670 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID543102 | Antimicrobial activity against Pseudomonas lini isolate C701 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1546200 | Antifungal activity against Aspergillus niger NCIM 545 after 48 hrs by NCCLS protocol based method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID336086 | Antimicrobial activity against Candida albicans NIH B311 by twofold serial macrobroth dilution assay | 1993 | Journal of natural products, Nov, Volume: 56, Issue:11 | Antimicrobial compounds from Petalostemum purpureum. |
| AID143701 | Antimycobacterial activity against Mycobacterium avium CIP 103317 | 1998 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 8, Issue:20 | Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis. |
| AID321428 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by microdilution test | 2008 | Bioorganic & medicinal chemistry, Feb-01, Volume: 16, Issue:3 | Sulfonamide-1,2,4-triazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID404898 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB33 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID600686 | Bactericidal activity against Enterococcus faecalis isolate obtained from human after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID206520 | Tested for the antimicrobial activity as minimum inhibitory concentration against Staphylococcus hominis ATCC 27844 | 2002 | Bioorganic & medicinal chemistry letters, Mar-11, Volume: 12, Issue:5 | New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation. |
| AID1546643 | Antibacterial activity against Escherichia coli MTCC 443 assessed as diameter of zone of inhibition at 200 ug/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID279904 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 7.8 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID1055960 | Antimycobacterial activity against streptomycin-resistant Mycobacterium tuberculosis ATCC 35820 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID376316 | Antibacterial activity against Proteus mirabilis isolate after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID600676 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID404900 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB40 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID445290 | Antibacterial activity against Escherichia coli by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID1272619 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 14 days by broth microdilution method | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. |
| AID1104313 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID283656 | Increase in ROS levels in Escherichia coli K12 MG1655 assessed as ratio of ROS with antibiotic to ROS without antibiotic | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID561104 | Antibacterial activity against Pasteurella multocida BB1038 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID1079943 | Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] | |||
| AID424599 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH357 (SCV-29) harboring TAA stop codon at nucleotide 301 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID585423 | Antimicrobial activity against oqxAB positive Escherichia coli C600 G262-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1054726 | Antibacterial activity against Bacillus subtilis (Ehrenberg) Cohn ATCC 6051 after overnight incubation by broth microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 23, Issue:23 | Pahangensin A and B, two new antibacterial diterpenes from the rhizomes of Alpinia pahangensis Ridley. |
| AID376315 | Antibacterial activity against Escherichia coli ATCC 35218 after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID445330 | Cytotoxicity against human A549 cells | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID376323 | Antibacterial activity against Sarcina lutea ATCC 9341 after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID1474166 | Liver toxicity in human assessed as induction of drug-induced liver injury by measuring severity class index | 2016 | Drug discovery today, Apr, Volume: 21, Issue:4 | DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. |
| AID1168610 | Antibacterial activity against Klebsiella pneumoniae incubated for 24 hrs by agar microdilution method | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets. |
| AID278552 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium longum ATCC 15707 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1179279 | Antimicrobial activity against Enterobacter aerogenes MTCC 111 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID537111 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis after 3 to 28 days by twofold dilution method | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22 | Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin. |
| AID540181 | Antibacterial activity against Escherichia coli NCIM 2345 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis and anti-tubercular and antimicrobial activities of some 2r,4c-diaryl-3-azabicyclo[3.3.1]nonan-9-one N-isonicotinoylhydrazone derivatives. |
| AID601251 | Antibacterial activity against Salmonella typhi assessed as 99.5% bacterial killing using 1 x 10'4 CFU/ml inoculum after 72 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID633856 | Antibacterial activity against Staphylococcus aureus ATCC 6538 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID1105380 | Antibacterial activity against Erwinia chrysanthemi ITCC B-40 assessed as as growth inhibition after 24 hr by broth dilution method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID1091749 | Antibacterial activity against Bacillus subtilis MTCC 441 assessed as inhibition zones at 100 ug/disk at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID1333278 | Antimycobacterial activity against Mycobacterium smegmatis MC2 155 assessed as inhibition of respiratory ATP synthesis by measuring ATP level at 4 times MIC measured after 6 hrs by luciferase reporter gene assay (Rvb = 212.7%) | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID442427 | Antimicrobial activity against Escherichia coli after 24 hrs by microdilution technique | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID381177 | Antibacterial activity against Escherichia coli after 24 to 72 hrs by disk diffusion method | 1999 | Journal of natural products, Sep, Volume: 62, Issue:9 | Antimicrobial and antitumor activities of mycosporulone. |
| AID278549 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium breve ATCC 15700 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID245104 | In vitro minimum inhibitory concentration against vancomycin-resistant Enterococcus faecium NCTC 12202 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2 | Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones. |
| AID294741 | Antibacterial activity against Salmonella typhi at 0.25% (w/v) concentration after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID719312 | Antimicrobial activity against Escherichia coli NCIM 2574 by broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID1079937 | Severe hepatitis, defined as possibly life-threatening liver failure or through clinical observations. Value is number of references indexed. [column 'MASS' in source] | |||
| AID278567 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium thermophilum ATCC 25866 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID382574 | Antibacterial activity against Vibrio cholerae assessed as diameter of inhibition zone at 0.25% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID644176 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID279881 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 3.9 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID747762 | Antibacterial activity against Bacillus subtilis after 24 hrs by broth dilution method | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID595283 | Antimicrobial activity against Klebsiella pneumoniae ATCC 16425 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, spectral, crystal structure and in vitro antimicrobial evaluation of imidazole/benzotriazole substituted piperidin-4-one derivatives. |
| AID1233484 | Antimicrobial activity against Klebsiella pneumoniae MTCC 109 assessed as inhibition of visual microbial growth incubated for 24 hrs at 37 degC | 2015 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 25, Issue:14 | Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. |
| AID166718 | Tested for binding affinity against RNA construct D; n.b. means no observable binding | 2002 | Bioorganic & medicinal chemistry letters, Feb-11, Volume: 12, Issue:3 | Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers. |
| AID569261 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus 873 | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID294551 | Antimicrobial activity against Pseudomonas aeruginosa ATCC 15442 at 10 ug by disk diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Rapid synthesis of sulfone derivatives as potential anti-infectious agents. |
| AID600685 | Bactericidal activity against Escherichia coli ATCC 35210 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID562386 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID637081 | Antibacterial activity against Bacillus cereus ATCC 11778 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID379425 | Antibacterial activity against Escherichia coli DSM10290 at 5 ug after 24 hrs by agar diffusion assay | 2006 | Journal of natural products, Feb, Volume: 69, Issue:2 | Cytotoxic isomalabaricane triterpenes from the marine sponge Rhabdastrella globostellata. |
| AID515294 | Antibacterial activity against Escherichia coli MTCC 443 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID600675 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID626287 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 0.5 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID544284 | Antimicrobial activity against Enterococcus faecalis NKH14 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID401460 | Antimicrobial activity against Escherichia coli ATCC 9637 by agar-dilution streak method | |||
| AID544276 | Antimicrobial activity against Enterococcus faecalis NKH6 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1241225 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) assessed as change in total free energy by thermodynamic assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID648377 | Antibacterial activity against Proteus vulgaris MTCC 1771 after 24 hrs by twofold serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID277996 | Antibacterial activity against Staphylococcus albus | 2007 | Journal of natural products, Feb, Volume: 70, Issue:2 | Antimicrobial ambiguines from the cyanobacterium Fischerella sp. collected in Israel. |
| AID544271 | Antimicrobial activity against Enterococcus faecalis NKH1 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1156886 | Antimicrobial activity against Aspergillus clavatus MTCC 1323 at 100 ug/disc after 48 hrs by agar cup plate method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID1565894 | Antibacterial activity against Bacillus proteus ATCC 8427 assessed as growth inhibition measured after 24 hrs by two-fold broth dilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | Design, synthesis and biological evaluation of novel diazaspiro[4.5]decan-1-one derivatives as potential chitin synthase inhibitors and antifungal agents. |
| AID1186775 | Antibacterial activity against Staphylococcus aureus MTCC 96 after 24 hrs by agar well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17 | Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: synthesis, characterization and evaluation of anticancer and antimicrobial activities. |
| AID442411 | Antimicrobial activity against Escherichia coli at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1055962 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolate X005282 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID92473 | Denaturation rate constant of IF2 in the presence of aminoglycoside | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6 | Inhibition of bacterial IF2 binding to fMet-tRNA((fMet)) by aminoglycosides. |
| AID442406 | Antimicrobial activity against Salmonella Typhimurium at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID544019 | Antimicrobial activity against Acinetobacter lwoffii isolate C15 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID625283 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID1594070 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as reduction in bacterial cell viability incubated for 20 to 24 hrs by REMA method | 2019 | Bioorganic & medicinal chemistry, 06-15, Volume: 27, Issue:12 | Design, synthesis, in-silico studies and biological screening of quinazolinone analogues as potential antibacterial agents against MRSA. |
| AID440768 | Antibacterial activity against Escherichia coli after 24-48 hrs by microdilution susceptibility test | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | Enaminonitrile in heterocyclic synthesis: synthesis and antimicrobial evaluation of some new pyrazole, isoxazole and pyrimidine derivatives incorporating a benzothiazole moiety. |
| AID1255668 | Antibacterial activity against Staphylococcus aureus ATCC 6538P assessed as growth inhibition at 100 ug/ml after 8 to 24 hrs by agar well diffusion method | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID92477 | Maximal inhibition of the aminoglycoside on Staphylococcus aureus IF-2 binding to fMet-tRNA(fMet) | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6 | Inhibition of bacterial IF2 binding to fMet-tRNA((fMet)) by aminoglycosides. |
| AID1247096 | Antibacterial activity against Bacillus subtilis after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID1555426 | Antibacterial activity against Escherichia coli assessed as diameter of zone of inhibition at 10 ug/disc by disc diffusion method | 2019 | European journal of medicinal chemistry, Aug-15, Volume: 176 | Phytochemical and pharmacological attributes of piperine: A bioactive ingredient of black pepper. |
| AID1511406 | Antibacterial activity against Escherichia coli assessed as reduction in bacterial cell growth incubated for 24 hrs by filter paper assay | 2019 | Bioorganic & medicinal chemistry, 11-01, Volume: 27, Issue:21 | Synthesis and biological evaluation of calycanthaceous alkaloid analogs. |
| AID1168608 | Antibacterial activity against Xanthomonas oryzae incubated for 24 hrs by agar microdilution method | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets. |
| AID278860 | Antiproliferative effect against HeLa cells after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID636965 | Antibacterial activity against Bacillus mycoides DSMZ 274 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1577329 | Antimycobacterial activity against multi-drug resistant Mycobacterium tuberculosis Praha 4 after 14 days | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. |
| AID424594 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH349 (SCV-21) harboring -1 frameshift mutation at nucleotide 404 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID464207 | Antibacterial activity against Escherichia coli ATCC 25922 after 48 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Synthesis, in vitro antibacterial and antifungal evaluations of new alpha-hydroxyphosphonate and new alpha-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline. |
| AID144867 | Antibacterial activity was evaluated against Mycobacterium tuberculosis (clinical isolate 1104) | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID419567 | Antibacterial activity against Bacillus stearothermophilus MTCC 8508 at 50 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID1075580 | Antimicrobial activity against Escherichia coli ATCC 25922 after 18 to 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents. |
| AID618737 | Antimicrobial activity against Mycobacterium tuberculosis H37Rv after 4 weeks by agar dilution assay | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18 | Synthesis and biological evaluation of substituted 4-arylthiazol-2-amino derivatives as potent growth inhibitors of replicating Mycobacterium tuberculosis H₃₇Rv. |
| AID656227 | Antimycobacterial activity against isoniazid-, rifampin-resistant Mycobacterium tuberculosis after 16 to 24 hrs by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. |
| AID258714 | Antibacterial activity against gram negative Klebsiella aerogenes(MTCC 39) | 2006 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 16, Issue:1 | Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents. |
| AID326539 | Antimicrobial activity against Mycobacterium abscessus NTU445 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID753880 | Antibacterial activity against Serratia marcescens ATCC 13880 assessed as growth inhibition at 10 ug after 24 hrs by agar diffusion method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthesis, antibacterial activity and cytotoxicity of new fused pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-c][1,2,4]triazine derivatives from new 5-aminopyrazoles. |
| AID1179280 | Antimicrobial activity against Staphylococcus aureus MTCC 96 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID1435649 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 4 after 14 days by micromethod | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. |
| AID424587 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH377 (SCV-49) harboring +1 frameshift mutation at nucleotide 23 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID442400 | Antimicrobial activity against Bacillus cereus at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID544024 | Antimicrobial activity against Acinetobacter calcoaceticus isolate C35 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID456088 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1104316 | Antibacterial activity against Listeria monocytogenes NCTC 7973 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1274477 | Antibacterial activity against Methicillin-resistant Staphylococcus aureus N 315 after 24 hrs by two-fold serial dilution method | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis and biological evaluation of novel phosphoramidate derivatives of coumarin as chitin synthase inhibitors and antifungal agents. |
| AID562593 | Antimicrobial activity against Enterococcus faecalis expressing VanA gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID456076 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID294761 | Antibacterial activity against Staphylococcus aureus after 2 weeks by broth dilution method | 2007 | Bioorganic & medicinal chemistry letters, May-01, Volume: 17, Issue:9 | Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus. |
| AID648390 | Antibacterial activity against Salmonella Typhimurium MTCC 1251 at 10 ug/disc after 24 hrs by disc diffusion assay | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID530235 | Antimicrobial activity against Mycobacterium bovis BCG ML1034 by microplate Alamar blue assay | 2008 | Antimicrobial agents and chemotherapy, Jul, Volume: 52, Issue:7 | Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. |
| AID456086 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID544009 | Antimicrobial activity against Providencia stuartii isolate C167 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1061248 | Antimicrobial activity against Pseudomonas aeruginosa at 1 mg/ml by well plate method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Synthesis and biological evaluation of novel substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1-b] [1,3,4] thiadiazole derivatives. |
| AID1600170 | Antibacterial activity against Proteus mirabilis NCIM 2388 assessed as zone of inhibition at 80 ug/well incubated for 24 to 48 hrs by by agar well diffusion method | 2019 | European journal of medicinal chemistry, Oct-01, Volume: 179 | Synthesis of new thiazolyl-pyrazolyl-1,2,3-triazole derivatives as potential antimicrobial agents. |
| AID285161 | Antimicrobial activity against non replicating persistence Mycobacterium tuberculosis H37Rv in anaerobic condition assessed as relative light unit after 11 days by LORA assay | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. |
| AID456089 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID285337 | Antimicrobial activity against Escherichia coli qnrA1 producing urinary specimen isolate 13.52 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | First report of plasmid-mediated qnrA1 in a ciprofloxacin-resistant Escherichia coli strain in Latin America. |
| AID1570735 | Antimicrobial activity against Enterococcus faecium AUS0004 at 300 ug/disk incubated for 20 +/- 4 hrs by agar disk diffusion method | 2019 | Bioorganic & medicinal chemistry, 11-01, Volume: 27, Issue:21 | Synthesis and evaluation of 1,3,4-oxadiazole derivatives for development as broad-spectrum antibiotics. |
| AID456358 | Antibacterial activity against Klebsiella pneumoniae NCIB 418 after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID424832 | Ratio of MIC for kanamycin-resistant Staphylococcus aureus harboring mutations in FusE gene to MIC for wild type kanamycin-susceptible Staphylococcus aureus AH001 | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1240997 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 6 days by MTT assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Guanidinium compounds with sub-micromolar activities against Mycobacterium tuberculosis. Synthesis, characterization and biological evaluations. |
| AID1566490 | Inhibition of Dicer mediated biotinylated pre-miRNA-21 (unknown origin) maturation at 1 mM measured after 15 mins by cat-ELCCA relative to control | 2019 | ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5 | Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. |
| AID1241210 | Binding affinity to 5'-FAM-pre-miR-17 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID626286 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 0.5 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID434661 | Antibacterial activity against Staphylococcus aureus ATCC 25825 after 24 hrs by twofold serial dilution method | 2009 | Bioorganic & medicinal chemistry letters, May-15, Volume: 19, Issue:10 | Design, synthesis and biological evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-1,3-thiazolidin-4-ones as a new class of antimicrobial agents. |
| AID206634 | Compound (isolated from leaves of Cistus monspeliensis) was tested for antimicrobial activity against Staphylococcus aureus (ATCC 6538) | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | A simple and rapid method for the differentiation of C-13 manoyl oxide epimers in biologically important samples using GC-MS analysis supported with NMR spectroscopy and computational chemistry results. |
| AID382577 | Antibacterial activity against Pseudomonas aeruginosa assessed as diameter of inhibition zone at 0.5% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID464056 | Antibacterial activity against Sarcina lutea ATCC 9341 after 48 hrs by serial dilution technique | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Sesquiterpene lactones from Anthemis melanolepis and their antibacterial and cytotoxic activities. Prediction of their pharmacokinetic profile. |
| AID464209 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Synthesis, in vitro antibacterial and antifungal evaluations of new alpha-hydroxyphosphonate and new alpha-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline. |
| AID357042 | Antibacterial activity against Staphylococcus aureus at 10 ug/disk by disk diffusion method | 2001 | Journal of natural products, Jul, Volume: 64, Issue:7 | Isolation and bioactivities of constitutents of the roots of Garcinia atroviridis. |
| AID1179265 | Antimicrobial activity against Micrococcus luteus MTCC 106 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID1104314 | Antibacterial activity against Micrococcus flavus ATCC 10240 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1055936 | Antimycobacterial activity against Mycobacterium tuberculosis harboring luxABCDE under hypoxic condition after 10 days by MABA assay in presence of 4% bovine serum albumin | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1274478 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by two-fold serial dilution method | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis and biological evaluation of novel phosphoramidate derivatives of coumarin as chitin synthase inhibitors and antifungal agents. |
| AID1456560 | Antibacterial activity against Streptococcus mutans MTCC 890 assessed as diameter of inhibition zone measured after 20 hrs by agar well diffusion method | |||
| AID1201581 | Antibacterial activity against Salmonella typhi at 0.5 mg/ml incubated for 18 hrs by well plate technique | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. |
| AID1265024 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 5 days by microplate alamar blue assay | 2015 | European journal of medicinal chemistry, Dec-01, Volume: 106 | Design of new phenothiazine-thiadiazole hybrids via molecular hybridization approach for the development of potent antitubercular agents. |
| AID442478 | Antibacterial activity against Staphylococcus aureus MTCC 96 by broth dilution method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Click chemistry: studies on the synthesis of novel fluorous tagged triazol-4-yl substituted quinazoline derivatives and their biological evaluation--theoretical and experimental validation. |
| AID279873 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 1000 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID608662 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition at 1000 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID358134 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 48 hrs by twofold serial dilution method | |||
| AID563501 | Antimicrobial activity against cetylpyridinium chloride-resistant Serratia marcescens 01 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID562385 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID456078 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID355887 | Antimicrobial activity against Proteus mirabilis isolates after 36 hrs under aerobic condition by microdilution method | 2003 | Journal of natural products, May, Volume: 66, Issue:5 | Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity. |
| AID424827 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH422 harboring +2 frameshift mutation at nucleotide 222 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID689075 | Antifungal activity against Septoria tritici assessed as zone of inhibition at 0.05 mg by agar diffusion method | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Sinularosides A and B, bioactive 9,11-secosteroidal glycosides from the South China Sea soft coral Sinularia humilis Ofwegen. |
| AID245016 | Minimum inhibitory concentration against Klebsiella aerogenes (Gram-negative) in broth | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 2,4,6-tri substituted s-triazines. |
| AID442477 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth dilution method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Click chemistry: studies on the synthesis of novel fluorous tagged triazol-4-yl substituted quinazoline derivatives and their biological evaluation--theoretical and experimental validation. |
| AID619775 | Antibacterial activity against Escherichia coli RCMB 000103 at 30 mg/ml after 24 hrs by agar well diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Design and synthesis of some new thiophene, thienopyrimidine and thienothiadiazine derivatives of antipyrine as potential antimicrobial agents. |
| AID1601230 | Antitubercular activity against Mycobacterium tuberculosis H37Rv incubated for 5 days by microplate alamar blue assay | 2019 | Bioorganic & medicinal chemistry, 10-15, Volume: 27, Issue:20 | A click chemistry approach for the synthesis of cyclic ureido tethered coumarinyl and 1-aza coumarinyl 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis H37Rv and their in silico studies. |
| AID723721 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID294965 | Antibacterial activity against Escherichia coli ATCC 23556 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID530052 | Antimicrobial activity against Staphylococcus aureus RN4220 expressing gyrB D437N mutant gene by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors. |
| AID289150 | Antimycobacterial activity against streptomycin and isoniazid-resistant Mycobacterium tuberculosis CIBIN 675 isolates | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines. |
| AID1454342 | Antibacterial activity Staphylococcus epidermidis MTCC 9041 by agar well method | 2017 | Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15 | Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides. |
| AID544283 | Antimicrobial activity against Enterococcus faecalis NKH13 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1156889 | Antimicrobial activity against Candida albicans MTCC 277 after 24 hrs by NCCLS M7-A5 method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID1153326 | Antimycobacterial activity against Mycobacterium phlei ATCC 355 after 1 day by alamar blue assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 24, Issue:13 | Design, synthesis and antimycobacterial activity evaluation of natural oridonin derivatives. |
| AID733703 | Antibacterial activity against Proteus vulgaris MTCC 1771 after 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID733715 | Antibacterial activity against Salmonella typhimurium MTCC 1251 at 1 mg/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID283648 | Susceptibility of Escherichia coli K12 MG1655 in presence of 10 mM glutathione by agar dilution method relative to control | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID278858 | Antiproliferative effect against MG63 cells assessed as BrdU incorporation into DNA after 48 hrs after 48 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. |
| AID258713 | Antibacterial activity against gram negative Pseudomonas aeruginosa (MTCC 741) | 2006 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 16, Issue:1 | Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents. |
| AID283654 | Antibacterial activity against Escherichia coli K12 DH5alpha in presence of 10 mM ascorbic acid | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID419575 | Antibacterial activity against Bacillus subtilis MTCC 8509 after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID737340 | Antimicrobial activity against Escherichia coli MTCC 723 at 1000 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID569256 | Antimycobacterial activity against Mycobacterium bovis BCG str. Tokyo 172 | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID419564 | Antibacterial activity against Bacillus subtilis MTCC 8509 at 50 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID716924 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 1000 ug/mL after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core. |
| AID585427 | Antimicrobial activity against oqxAB positive Escherichia coli C600 XT11-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID440603 | Antibacterial activity against Escherichia coli assessed as zone of inhibition diameter at 1 mg/mL after 24 hrs by twofold serial dilution method | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | Enaminonitrile in heterocyclic synthesis: synthesis and antimicrobial evaluation of some new pyrazole, isoxazole and pyrimidine derivatives incorporating a benzothiazole moiety. |
| AID1296384 | Antimycobacterial activity against multi drug resistant Mycobacterium tuberculosis 9449/2007 after 14 days by microdilution method | 2016 | Journal of medicinal chemistry, Mar-24, Volume: 59, Issue:6 | Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. |
| AID544012 | Antimicrobial activity against Arthrobacter arilaitensis isolate C361 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID404096 | Antimicrobial activity against Bacillus cereus isolates by microdilution method | 2005 | Journal of natural products, Sep, Volume: 68, Issue:9 | Sesquiterpene lactones from Centaurea spinosa and their antibacterial and cytotoxic activities. |
| AID637039 | Antibacterial activity against Bacillus megaterium NRRL 1353895 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID293802 | Antibacterial activity against Pseudomonas aeruginosa | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives. |
| AID594272 | Antimicrobial activity against Bacillus subtilis NCIM 2063/ATCC 6633 at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID1463959 | Antimycobacterial activity MDR/XDR against Mycobacterium tuberculosis isolate 9449/2007 incubated for 14 days by micromethod | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents. |
| AID1174107 | Antimycobacterial activity against isoniazid, rifampin, streptomycin, ofloxacin-resistant Mycobacterium tuberculosis after 7 days by microplate Alamar blue assay | 2015 | European journal of medicinal chemistry, Jan-07, Volume: 89 | Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis. |
| AID542420 | Antimicrobial activity against Acinetobacter sp. N2 isolate C439 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID683685 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 7 days by microplate alamar blue assay | 2012 | European journal of medicinal chemistry, Nov, Volume: 57 | The design, synthesis, in silico ADME profiling, antiplasmodial and antimycobacterial evaluation of new arylamino quinoline derivatives. |
| AID1061250 | Antimicrobial activity against Bacillus subtilis at 1 mg/ml by well plate method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Synthesis and biological evaluation of novel substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1-b] [1,3,4] thiadiazole derivatives. |
| AID534824 | Antimicrobial activity against ciprofloxacin-resistant Campylobacter fetus subsp. fetus 1516477 human isolate harboring tet(44) and ant(6)-Ib resistance gene in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID620348 | Antibacterial activity against Pseudomonas aeruginosa RCMB 000102 at 30 ug/ml after 24 hrs by diffusion agar technique | 2011 | European journal of medicinal chemistry, Oct, Volume: 46, Issue:10 | Synthesis and anti-microbial activity of some 1- substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives. |
| AID445287 | Antibacterial activity against Mycobacterium avium SmO by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID587242 | Antimicrobial activity against Staphylococcus aureus DSM 799 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID333644 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv at 0.004 mg/ml by rapid radiometric method | 2004 | Journal of natural products, Nov, Volume: 67, Issue:11 | Antibacterial activity of naphthoquinones and triterpenoids from Euclea natalensis root bark. |
| AID436793 | Antitubercular activity against Mycobacterium tuberculosis H37Rv at 7.25 ug/ml by microplate alamar blue assay | 2009 | European journal of medicinal chemistry, Oct, Volume: 44, Issue:10 | Synthesis and evaluation of in vitro anti-microbial and anti-tubercular activity of 2-styryl benzimidazoles. |
| AID532985 | Antibacterial activity against Escherichia coli MG1655 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID545533 | Antibacterial activity against Escherichia coli ATCC 25835 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide. |
| AID446150 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis H37Rv after 16 to 24 hrs by microplate alamar | 2010 | Journal of medicinal chemistry, Jan-28, Volume: 53, Issue:2 | Rational design of 5-phenyl-3-isoxazolecarboxylic acid ethyl esters as growth inhibitors of Mycobacterium tuberculosis. a potent and selective series for further drug development. |
| AID294738 | Antibacterial activity against Escherichia coli at 0.25% (w/v) concentration after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID723725 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1296386 | Antimycobacterial activity against multi drug resistant Mycobacterium tuberculosis Praha 1 after 14 days by microdilution method | 2016 | Journal of medicinal chemistry, Mar-24, Volume: 59, Issue:6 | Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. |
| AID723714 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID626285 | Antibacterial activity against Escherichia coli ATCC 25922 at 0.5 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID733701 | Antibacterial activity against Micrococcus luteus MTCC 106 after 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID355493 | Antimicrobial activity against Bacillus subtilis ATCC 6633 after 24 hrs by twofold serial dilution method | |||
| AID1156688 | Antimicrobial activity against Enterobacter aerogenes MTCC 111 assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID495750 | Antimicrobial activity against Escherichia coli J5 by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID408870 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID1555427 | Antibacterial activity against Staphylococcus aureus assessed as diameter of zone of inhibition at 10 ug/disc by disc diffusion method | 2019 | European journal of medicinal chemistry, Aug-15, Volume: 176 | Phytochemical and pharmacological attributes of piperine: A bioactive ingredient of black pepper. |
| AID562596 | Antimicrobial activity against Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID716926 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 1000 ug/mL after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core. |
| AID408875 | Antimycobacterial activity against Mycobacterium tuberculosis 103471 | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID400008 | Antimicrobial activity against Escherichia coli using distilled water as solvent by agar diffusion test | |||
| AID278524 | Antimicrobial activity against Bifidobacterium bifidum BB12 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID278546 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium bifidum R0071 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID515296 | Antibacterial activity against Klebsiella pneumoniae MTCC 39 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID144866 | Antibacterial activity was evaluated against Mycobacterium tuberculosis (ATCC) | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID545534 | Antibacterial activity against Klebsiella pneumoniae ATCC 15490 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Dec, Volume: 45, Issue:12 | Regiospecific synthesis and biological evaluation of spirooxindolopyrrolizidines via [3+2] cycloaddition of azomethine ylide. |
| AID615568 | Antimicrobial activity against Bacillus subtilis at 100 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID1156677 | Antimicrobial activity against Enterobacter aerogenes MTCC 111 assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID336091 | Antimicrobial activity against Bacillus subtilis ATCC 6633 by twofold serial macrobroth dilution assay | 1993 | Journal of natural products, Nov, Volume: 56, Issue:11 | Antimicrobial compounds from Petalostemum purpureum. |
| AID279875 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 250 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID357043 | Antibacterial activity against Bacillus cereus at 10 ug/disk by disk diffusion method | 2001 | Journal of natural products, Jul, Volume: 64, Issue:7 | Isolation and bioactivities of constitutents of the roots of Garcinia atroviridis. |
| AID424595 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH374 (SCV-46) harboring -5 frameshift mutation at nucleotide 236-240 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID382572 | Antibacterial activity against Staphylococcus aureus assessed as diameter of inhibition zone at 0.25% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID206693 | Antibacterial activity against gram positive bacteria Staphylococcus aureus was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID278541 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium longum R0175 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID534342 | Antimicrobial activity against Burkholderia pseudomallei Bp58 harboring deleted bpeR::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID355266 | Antitubercular activity against Mycobacterium tuberculosis H37Rv after 21 days by broth microdilution method | 1997 | Journal of natural products, Dec, Volume: 60, Issue:12 | Norditerpenoids and diterpenoids from Salvia multicaulis with antituberculous activity. |
| AID1079935 | Cytolytic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is > 5 (see ACUTE). Value is number of references indexed. [column 'CYTOL' in source] | |||
| AID1274479 | Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by two-fold serial dilution method | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis and biological evaluation of novel phosphoramidate derivatives of coumarin as chitin synthase inhibitors and antifungal agents. |
| AID419827 | Antibacterial activity against Staphylococcus aureus MTCC 96 at 1000 ug/ml after 24 hrs by agar diffusion method | 2009 | European journal of medicinal chemistry, Jun, Volume: 44, Issue:6 | Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde. |
| AID424590 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH346 (SCV-18) harboring -1 frameshift mutation at nucleotide 238 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID626284 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 1 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID1179278 | Antimicrobial activity against Micrococcus luteus MTCC 106 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID496397 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT2 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID1156676 | Antimicrobial activity against Micrococcus luteus MTCC 106 assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID1653584 | Anti-leprotic activity against Mycobacterium leprae infected in BALB/c weanling mouse assessed as bacteria killing at 150 mg/kg, ip administrated cotreated with 0.0001% dietary dapsone for 60 days and measured after 1 year by most probable number techniqu | 2019 | Bioorganic & medicinal chemistry, 07-01, Volume: 27, Issue:13 | Insights of synthetic analogues of anti-leprosy agents. |
| AID166714 | Tested for binding affinity against RNA construct B; n.b. means no observable binding | 2002 | Bioorganic & medicinal chemistry letters, Feb-11, Volume: 12, Issue:3 | Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers. |
| AID725545 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus after 20 hrs by liquid microdilution method | 2013 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 23, Issue:3 | Discovery of nosokophic acid, a predicted intermediate of moenomycins, from nosokomycin-producing Streptomyces sp. K04-0144. |
| AID1546087 | Antimicrobial activity against Escherichia coli | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID279867 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 125 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID424581 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH329 (SCV-1) harboring Arg659Cys mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID92474 | Inhibitory activity against the displacement of Picogreen from fMet-tRNA(fMet) by the aminoglycoside | 2003 | Bioorganic & medicinal chemistry letters, Mar-24, Volume: 13, Issue:6 | Inhibition of bacterial IF2 binding to fMet-tRNA((fMet)) by aminoglycosides. |
| AID1183299 | Antibacterial activity against Pseudomonas aeruginosa | 2014 | European journal of medicinal chemistry, Sep-12, Volume: 84 | Design, synthesis and anti-mycobacterial activity of 1,2,3,5-tetrasubstituted pyrrolyl-N-acetic acid derivatives. |
| AID449209 | Antimycobacterial activity against rifampicin-resistant Mycobacterium tuberculosis ATCC 35838 by twofold agar dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation. |
| AID1204391 | Antibacterial activity against Staphylococcus aureus assessed as lowest concentration required to reduce growth by 1% after 8 hrs by ELISA plate reader analysis relative to control | 2015 | European journal of medicinal chemistry, Jun-05, Volume: 97 | Benzaldehyde Schiff bases regulation to the metabolism, hemolysis, and virulence genes expression in vitro and their structure-microbicidal activity relationship. |
| AID1079948 | Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source] | |||
| AID1179268 | Antimicrobial activity against Salmonella typhimurium MTCC 1251 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID464052 | Antibacterial activity against Escherichia coli ATCC 35218 after 48 hrs by serial dilution technique | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Sesquiterpene lactones from Anthemis melanolepis and their antibacterial and cytotoxic activities. Prediction of their pharmacokinetic profile. |
| AID1158049 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv assessed as compound level causing less than 2% growth after 7 days by serial dilution method | 2014 | Journal of natural products, Jun-27, Volume: 77, Issue:6 | Identification and bioactivity of 3-epi-xestoaminol C isolated from the New Zealand brown alga Xiphophora chondrophylla. |
| AID544273 | Antimicrobial activity against Enterococcus faecalis NKH3 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID747760 | Antibacterial activity against Escherichia coli after 24 hrs by broth dilution method | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID626340 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 0.25 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID1079946 | Presence of at least one case with successful reintroduction. [column 'REINT' in source] | |||
| AID1315652 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv measured daily for 8 days by GFP-based fluorescence assay | 2016 | Journal of natural products, 06-24, Volume: 79, Issue:6 | Lovastatin Analogues from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178. |
| AID603191 | Antibacterial activity against Staphylococcus epidermidis MTCC 2639 by broth microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 21, Issue:13 | Efficient synthesis, structural characterization and anti-microbial activity of chiral aryl boronate esters of 1,2-O-isopropylidene-α-D-xylofuranose. |
| AID681768 | TP_TRANSPORTER: inhibition of PAH uptake (PAH: 2 uM, Streptomycin: 2000 uM) in Xenopus laevis oocytes | 1999 | The Journal of pharmacology and experimental therapeutics, Aug, Volume: 290, Issue:2 | The interaction and transport of beta-lactam antibiotics with the cloned rat renal organic anion transporter 1. |
| AID326548 | Antimicrobial activity against Mycobacterium abscessus R53 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID568437 | Antimicrobial activity against Klebsiella pneumoniae MTCC 39 after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Stereoselective first total synthesis, confirmation of the absolute configuration and bioevaluation of botryolide-E. |
| AID1303896 | Antibacterial activity against multidrug resistant Enterobacter cloacae subsp. cloacae CDC 442-68 (ATCC 13047) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID370069 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 14 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID456077 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1240998 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis MYC5165 after 6 days by MTT assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Guanidinium compounds with sub-micromolar activities against Mycobacterium tuberculosis. Synthesis, characterization and biological evaluations. |
| AID614917 | Antibacterial activity against Klebsiella pneumoniae ATCC 31488 after 24 hrs by broth micro dilution assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis, antimicrobial evaluation and QSAR analysis of novel nalidixic acid based 1,2,4-triazole derivatives. |
| AID424831 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH416 harboring deletion of nucleotide 395-398 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID737339 | Antimicrobial activity against Escherichia coli MTCC 723 at 750 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID1241206 | Inhibition of pre-miR-17 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID753882 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 assessed as growth inhibition at 10 ug after 24 hrs by agar diffusion method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthesis, antibacterial activity and cytotoxicity of new fused pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-c][1,2,4]triazine derivatives from new 5-aminopyrazoles. |
| AID1079940 | Granulomatous liver disease, proven histopathologically. Value is number of references indexed. [column 'GRAN' in source] | |||
| AID1105399 | Antibacterial activity against Staphylococcus aureus MTCC 3160 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID636964 | Antibacterial activity against Bacillus megaterium NRRL 1353895 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1227981 | Antimycobacterial activity against GFP expressing Mycobacterium tuberculosis H37Ra assessed as microbial growth inhibition incubated at 37 degC for 7 days by fluorescence based assay | 2015 | Journal of natural products, Apr-24, Volume: 78, Issue:4 | Eremophilane Sesquiterpenes and Diphenyl Thioethers from the Soil Fungus Penicillium copticola PSU-RSPG138. |
| AID278565 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium longum R0175 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1179282 | Antimicrobial activity against Klebsiella pneumoniae MTCC 109 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID588212 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID656232 | Antimycobacterial activity against isoniazid-, rifampin-, ofloxacin-, streptomycin-resistant Mycobacterium tuberculosis after 16 to 24 hrs by alamar blue assay | 2012 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 22, Issue:8 | Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosis. |
| AID1333272 | Antimycobacterial activity against Mycobacterium smegmatis MC2 155 assessed as inhibition of respiratory ATP synthesis by measuring ATP level at 2 times MIC measured after 3 hrs by luciferase reporter gene assay (Rvb = 158.3%) | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID1647342 | Antibacterial activity against Staphylococcus aureus by dilution assay | 2020 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2 | The bioisosteric modification of pyrazinamide derivatives led to potent antitubercular agents: Synthesis via click approach and molecular docking of pyrazine-1,2,3-triazoles. |
| AID611679 | Antibacterial activity against Bacillus megaterium at 0.05 mg by agar diffusion method | 2011 | Journal of natural products, Jul-22, Volume: 74, Issue:7 | Bioactive 11,20-epoxy-3,5(16)-diene briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. |
| AID644168 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1209455 | Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake | 2012 | Drug metabolism and disposition: the biological fate of chemicals, Jan, Volume: 40, Issue:1 | In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. |
| AID1527476 | Antibacterial activity against Lactobacillus casei NCIM-2651 assessed as reduction in microbial growth incubated for 24 hrs by broth dilution method | 2020 | European journal of medicinal chemistry, Jan-01, Volume: 185 | Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents. |
| AID294966 | Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 after 24 hrs by serial dilution method | 2007 | European journal of medicinal chemistry, Oct, Volume: 42, Issue:10 | Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles. |
| AID294734 | Antibacterial activity against Aeromonas hydrophila at 0.125% (w/v) concentration after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID568436 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 741 after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Stereoselective first total synthesis, confirmation of the absolute configuration and bioevaluation of botryolide-E. |
| AID1179287 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 741 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID449207 | Antimycobacterial activity against Mycobacterium tuberculosis CIP 103471 by twofold agar dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation. |
| AID258715 | Antibacterial activity against gram negative Chromobacterium violaceum(MTCC 2656) | 2006 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 16, Issue:1 | Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents. |
| AID408872 | Antimycobacterial activity against Mycobacterium avium CIP 103317 | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID603189 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 21, Issue:13 | Efficient synthesis, structural characterization and anti-microbial activity of chiral aryl boronate esters of 1,2-O-isopropylidene-α-D-xylofuranose. |
| AID440769 | Antibacterial activity against Pseudomonas aeruginosa after 24-48 hrs by microdilution susceptibility test | 2009 | European journal of medicinal chemistry, Dec, Volume: 44, Issue:12 | Enaminonitrile in heterocyclic synthesis: synthesis and antimicrobial evaluation of some new pyrazole, isoxazole and pyrimidine derivatives incorporating a benzothiazole moiety. |
| AID515323 | Antibacterial activity against Pseudomonas aeruginosa at 50 ug/ml after 24 to 48 hrs by cup-plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Synthesis and biological property of some novel 1,3,4-oxadiazoles. |
| AID1311820 | Antibacterial activity against ofloxacin-resistant Mycobacterium tuberculosis by two fold serial dilution method | 2016 | Bioorganic & medicinal chemistry, 09-15, Volume: 24, Issue:18 | Antibacterial and anticancer activity of a series of novel peptides incorporating cyclic tetra-substituted C(α) amino acids. |
| AID586085 | Antimicrobial activity against verocytotoxin-producing Escherichia coli isolate O157 obtained from human assessed as percentage of resistant isolates by disk diffusion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID1186783 | Antibacterial activity against Pseudomonas aeruginosa MTCC 4673 at 30 ug/ml after 24 hrs by agar well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17 | Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: synthesis, characterization and evaluation of anticancer and antimicrobial activities. |
| AID1247094 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID540210 | Clearance in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID776465 | Antimicrobial activity against Mycobacterium smegmatis ATCC 607 | 2013 | European journal of medicinal chemistry, Nov, Volume: 69 | Design, synthesis and biological activities of some 7-aminocephalosporanic acid derivatives. |
| AID1272602 | Antibacterial activity against Escherichia coli MTCC 443 after 24 hrs by broth microdilution technique | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. |
| AID442413 | Antimicrobial activity against Enterobacter cloacae at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID1476360 | Antitubercular activity against rifampicin resistant Mycobacterium tuberculosis H37Rv ATCC 35838 after 24 hrs by MABA method | 2017 | Journal of medicinal chemistry, 10-26, Volume: 60, Issue:20 | Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity. |
| AID587245 | Antimicrobial activity against Escherichia coli DSM 682 after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID320037 | Antibacterial activity against Pseudomonas aeruginosa by broth dilution method | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3 | Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates. |
| AID565993 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv by twofold agar dilution method | 2011 | European journal of medicinal chemistry, Jan, Volume: 46, Issue:1 | Synthesis and anti-mycobacterial activities of triazoloquinolones. |
| AID636967 | Antibacterial activity against Acinetobacter johnsonii ATCC 17909 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1104320 | Antibacterial activity against Escherichia coli ATCC 35210 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID540927 | Antimicrobial activity against Streptomyces coelicolor 1147 after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID1224523 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis Praha 1 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID1091744 | Antibacterial activity against Chromobacterium violaceum MTCC 2656 assessed as inhibition zones at 100 ug/disk at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID456432 | Antibacterial activity against Bacillus anthracis after 72 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID1055938 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv under normoxic condition after 7 days by MABA assay in presence of 4% bovine serum albumin | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID733712 | Antibacterial activity against Shigella flexneri MTCC 1457 at 1 mg/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID733713 | Antibacterial activity against Proteus vulgaris MTCC 1771 at 1 mg/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID530749 | Induction of PlytR::lacZ gene expression in Staphylococcus aureus SH1000 at 3 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID258712 | Antibacterial activity against gram positive Staphylococcus aureus(MTCC 96) | 2006 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 16, Issue:1 | Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents. |
| AID1055969 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID1079934 | Highest frequency of acute liver toxicity observed during clinical trials, expressed as a percentage. [column '% AIGUE' in source] | |||
| AID696347 | Antibacterial activity against Pseudomonas ATCC 27853 after 24 hrs by two fold serial dilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 22, Issue:21 | Design, synthesis, spectral and biological evaluation of novel 1-allyl substituted 2,6-diphenylpiperidin-4-ones and its derivatives of oximes/oxime ethers. |
| AID1153328 | Antimycobacterial activity against Mycobacterium marinum ATCC 927 after 7 days | 2014 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 24, Issue:13 | Design, synthesis and antimycobacterial activity evaluation of natural oridonin derivatives. |
| AID278547 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium bifidum ATCC 15696 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID544272 | Antimicrobial activity against Enterococcus faecalis NKH2 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID144024 | In vitro antibacterial activity against Mycobacterium gordonae 6427 | 1999 | Bioorganic & medicinal chemistry letters, Oct-18, Volume: 9, Issue:20 | New pyrrole derivatives as antimycobacterial agents analogs of BM212. |
| AID1546646 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as reduction in microbial growth after 24 hrs by CLSI based microdilution method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID1333168 | Induction of membrane integrity impairment in Mycobacterium bovis BCG ATCC 35734 assessed as reduction in intracellular pH at 16 times MIC by CMFDA dye based fluorescence spectroscopic method | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID294553 | Antimicrobial activity against Enterococcus hirae ATCC 10541 at 10 ug by disk diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Rapid synthesis of sulfone derivatives as potential anti-infectious agents. |
| AID414454 | Antitubercular activity against rifampin-resistant Mycobacterium tuberculosis H37Rv ATCC 27294 after 7 days by microplate alamar blue assay | 2009 | Journal of medicinal chemistry, Apr-09, Volume: 52, Issue:7 | Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium tuberculosis. |
| AID1193499 | Thermodynamic equilibrium solubility, log S of the compound simulated intestinal fluid at pH 6.8 at RT after 24 hrs by shake-flask method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. |
| AID1193497 | Thermodynamic equilibrium solubility, log S of the compound PBS at pH 7.4 at RT after 24 hrs by shake-flask method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. |
| AID625291 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver function tests abnormal | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID615569 | Antimicrobial activity against Staphylococcus aureus at 25 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID1168607 | Antibacterial activity against Xanthomonas oryzae at 50 ug/mL incubated for 24 hrs by agar well diffusion method | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets. |
| AID400005 | Antimicrobial activity against Pseudomonas aeruginosa using pH 4.0 buffer as solvent by agar diffusion test | |||
| AID600680 | Bactericidal activity against Bacillus cereus clinical isolate after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID1333106 | Antimycobacterial activity against Mycobacterium smegmatis MC2 155 after 24 hrs by broth dilution assay | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID206049 | Minimum inhibitory concentration against Staphylococcus epidermidis (ATCC 12228) | 2001 | Bioorganic & medicinal chemistry letters, Mar-26, Volume: 11, Issue:6 | Structure elucidation and conformational properties of a novel bioactive clerodane diterpene using a combination of high field NMR spectroscopy, computational analysis and X-ray diffraction. |
| AID245455 | Minimum inhibitory concentration against Staphylococcus aureus (Gram-positive) was determined by broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 2,4,6-tri substituted s-triazines. |
| AID608668 | Antibacterial activity against Salmonella Typhimurium assessed as zone of inhibition at 1000 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID278542 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium longum P/N 601377 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1186780 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 at 30 ug/ml after 24 hrs by agar well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17 | Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: synthesis, characterization and evaluation of anticancer and antimicrobial activities. |
| AID747759 | Antibacterial activity against Pseudomonas aeruginosa after 24 hrs by broth dilution method | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID449210 | Antimycobacterial activity against Mycobacterium avium CIP 103317 by twofold agar dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis, and microbiological evaluation. |
| AID619771 | Antibacterial activity against Bacillus subtilis RCMB 000107 at 30 mg/ml after 24 hrs by agar well diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Design and synthesis of some new thiophene, thienopyrimidine and thienothiadiazine derivatives of antipyrine as potential antimicrobial agents. |
| AID245437 | Minimum inhibitory concentration against Bacillus sphaericus (Gram-positive) was determined by broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 2,4,6-tri substituted s-triazines. |
| AID1186784 | Antibacterial activity against Pseudomonas aeruginosa MTCC 4673 after 24 hrs by agar well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17 | Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: synthesis, characterization and evaluation of anticancer and antimicrobial activities. |
| AID601247 | Antibacterial activity against Bacillus thuringiensis assessed as 99.5% bacterial killing using 1 x 10'4 CFU/ml inoculum after 72 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID495748 | Antimicrobial activity against Escherichia coli ATCC 25922 by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID774293 | Cytotoxicity against african green monkey Vero cells after 72 hrs by MTS-PMS assay | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID689078 | Antimicrobial activity against Chlorella fusca assessed as zone of inhibition at 0.05 mg by agar diffusion method | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Sinularosides A and B, bioactive 9,11-secosteroidal glycosides from the South China Sea soft coral Sinularia humilis Ofwegen. |
| AID1104318 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID666781 | Antifungal activity against Septoria tritici at 0.05 mg by agar diffusion test | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13 | Bioactive briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. |
| AID1487411 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth microdilution method | 2017 | Bioorganic & medicinal chemistry, 08-15, Volume: 25, Issue:16 | Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase. |
| AID401463 | Antimicrobial activity against Mycobacterium smegmatis ATCC 607 by agar-dilution streak method | |||
| AID207184 | Antibacterial activity against Staphylococcus aureus NCTC 6571 strain. | 2004 | Journal of medicinal chemistry, Apr-08, Volume: 47, Issue:8 | Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity. |
| AID1105400 | Antibacterial activity against Klebsiella pneumoniae MTCC 7028 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID496396 | Antibacterial activity against azide-resistant Escherichia coli J53 SXT1 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID723722 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID1546167 | Antimicrobial activity against Escherichia coli assessed as zone of inhibition at 5 mg/ml after 24 to 48 hrs by well diffusion method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID587762 | Antimicrobial activity against recombinant Mycobacterium ulcerans Mu1059 expressing luxAB from vibrio harveyi infected BALB/c mouse assessed as reduction in foodpad relative light unit after 1 week relative to basal level | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Using bioluminescence to monitor treatment response in real time in mice with Mycobacterium ulcerans infection. |
| AID733705 | Antibacterial activity against Salmonella typhimurium MTCC 1251 after 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID568435 | Antimicrobial activity against Escherichia coli MTCC 443 after 24 hrs by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Stereoselective first total synthesis, confirmation of the absolute configuration and bioevaluation of botryolide-E. |
| AID561103 | Antibacterial activity against Pasteurella multocida BB1037 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID456355 | Antibacterial activity against Staphylococcus aureus NCIB 8588 after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID424614 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH291 harboring Arg659His mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID448073 | Antibacterial activity against Ralstonia solanacearum at 50 mg/L after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Design, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)quinoline-3-carboxylic acid derivatives. |
| AID1241207 | Inhibition of pre-miR-373 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID1156890 | Antimicrobial activity against Candida tropicalis MTCC 184 after 24 hrs by NCCLS M7-A5 method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID544286 | Antimicrobial activity against Enterococcus faecalis NKH16 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID320038 | Antibacterial activity against Klebsiella pneumoniae by broth dilution method | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3 | Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates. |
| AID1179273 | Antimicrobial activity against Shigella flexneri MTCC 1457 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID1168611 | Antibacterial activity against Coagulase positive Staphylococcus at 50 ug/mL incubated for 24 hrs by agar well diffusion method | 2014 | European journal of medicinal chemistry, Nov-24, Volume: 87 | Implications of N-capped urea/thiourea and C-capped 3-(1-piperazinyl)-1,2-benzisothiazole with bridging Gly-Val/Phe-Gly-Val-Pro as therapeutic targets. |
| AID1456561 | Antibacterial activity against Pseudomonas sp. NCIM 2872 assessed as diameter of inhibition zone measured after 20 hrs by agar well diffusion method | |||
| AID1593046 | Antibacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as reduction in mycobacterial growth incubated for 5 days by MABA method | 2019 | European journal of medicinal chemistry, Apr-15, Volume: 168 | Molecular hybridization approach for phenothiazine incorporated 1,2,3-triazole hybrids as promising antimicrobial agents: Design, synthesis, molecular docking and in silico ADME studies. |
| AID1303893 | Antibacterial activity against multidrug resistant Klebsiella pneumoniae subsp. pneumoniae NCTC 9633 (ATCC 13883) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID1125794 | Antifungal activity against Candida albicans MTCC 183 assessed as diameter of growth inhibition zone at 10 ug/ml after 4 days by agar disc diffusion method | 2014 | European journal of medicinal chemistry, Apr-22, Volume: 77 | New polyfunctional imidazo[4,5-C]pyridine motifs: synthesis, crystal studies, docking studies and antimicrobial evaluation. |
| AID694227 | Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. |
| AID442404 | Antimicrobial activity against Pseudomonas aeruginosa at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID590140 | Antitubercular activity against Mycobacterium tuberculosis H37Rv by microplate alamar blue assay | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Novel thiolactone-isatin hybrids as potential antimalarial and antitubercular agents. |
| AID1105402 | Antibacterial activity against Bacillus thuringiensis MTCC 6941 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID1596683 | Bactericidal activity against Escherichia coli ATCC 35210 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID320034 | Antibacterial activity against Staphylococcus aureus by broth dilution method | 2008 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 18, Issue:3 | Synthesis and antimicrobial activity of novel C-linked imidazole glycoconjugates. |
| AID1179270 | Antimicrobial activity against Proteus vulgaris MTCC 1771 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID696345 | Antibacterial activity against Salmonella typhi ATCC 25021 after 24 hrs by two fold serial dilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 22, Issue:21 | Design, synthesis, spectral and biological evaluation of novel 1-allyl substituted 2,6-diphenylpiperidin-4-ones and its derivatives of oximes/oxime ethers. |
| AID534346 | Antimicrobial activity against Burkholderia pseudomallei Bp207 harboring deleted (bpeAB-oprA)::FRT gene after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID456433 | Antibacterial activity against Bacillus stearothermophilus NCIB 8222 after 72 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID689074 | Antifungal activity against Microbotryum violaceum assessed as zone of inhibition at 0.05 mg by agar diffusion method | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Sinularosides A and B, bioactive 9,11-secosteroidal glycosides from the South China Sea soft coral Sinularia humilis Ofwegen. |
| AID614002 | Antitubercular activity against Mycobacterium tuberculosis H37Rv after 3 weeks by turbidity assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | One-pot synthesis of pyrazoline derivatised carbazoles as antitubercular, anticancer agents, their DNA cleavage and antioxidant activities. |
| AID1435653 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 7357/1998 after 14 days by micromethod | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. |
| AID625446 | Antimicrobial activity against Staphylococcus aureus MTCC 96 by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Iodine-catalyzed conjugate addition of indoles onto en-1,4-dione: a novel synthesis of 3-(1-(1H-indol-3-yl)-2-oxo-2-phenylethyl)indolin-2-ones as antibacterial and antifungal agents. |
| AID1156674 | Antimicrobial activity against Staphylococcus aureus MTCC 96 assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID279903 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 15.6 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID608664 | Antibacterial activity against Staphylococcus aureus assessed as zone of inhibition at 1000 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID587244 | Antimicrobial activity against Pseudomonas aeruginosa DSM 1128 at 1 ug/ul after 24 hrs by disk diffusion method | 2011 | Journal of natural products, Feb-25, Volume: 74, Issue:2 | Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. |
| AID442403 | Antimicrobial activity against Escherichia coli at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID539691 | Antifungal activity against Staphylococcus aureus MTCC 96 by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Indium(III) chloride catalyzed three-component coupling reaction: a novel synthesis of 2-substituted aryl(indolyl)kojic acid derivatives as potent antifungal and antibacterial agents. |
| AID1201580 | Antibacterial activity against Salmonella typhi at 1 mg/ml incubated for 18 hrs by well plate technique | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. |
| AID1542739 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 measured after 18 hrs by broth dilution method | 2019 | Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10 | 6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers. |
| AID544027 | Antimicrobial activity against Acinetobacter rhizosphaerae isolate C44 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID283220 | Antimicrobial activity against Pseudomonas aeruginosa PA0905 | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. |
| AID562810 | Antimicrobial activity against Escherichia coli J53 harboring pEK499 plasmid encoding CTX-M extended-spectrum beta-lactamases | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID294550 | Antimicrobial activity against Escherichia coli ATCC 10536 at 10 ug by disk diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Rapid synthesis of sulfone derivatives as potential anti-infectious agents. |
| AID1233487 | Antimicrobial activity against Micrococcus luteus MTCC 106 assessed as inhibition of visual microbial growth incubated for 24 hrs at 37 degC | 2015 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 25, Issue:14 | Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. |
| AID532023 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60K containing pMH94 carrying the luxAB gene under the hsp60 promoter after 7 days determined according to CFU count by bioluminescence method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID733700 | Antibacterial activity against Enterobacter aerogenes MTCC 111 after 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID1104309 | Antibacterial activity against Proteus mirabilis at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID401461 | Antimicrobial activity against Salmonella gallinarum ATCC 9184 by agar-dilution streak method | |||
| AID1227450 | Antibacterial activity against Bacillus subtilis assessed as bacterial growth inhibition at 30 ug/ml after 24 hrs by cup-plate agar diffusion method | 2015 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 25, Issue:1 | One-pot multicomponent synthesis of indole incorporated thiazolylcoumarins and their antibacterial, anticancer and DNA cleavage studies. |
| AID244831 | Minimum inhibitory concentration against Escherichia coli | 2005 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 15, Issue:7 | Enhancement in antimicrobial activity of 2-(phenyl)-3-(2-butyl-4-chloro-1H-imidazolyl)-5-butylate isoxazolidine. |
| AID770969 | Antibacterial activity against Klebsiella pneumoniae MTCC 618 by broth dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Demonic axe-like conjugated alkynes in combating microbes. |
| AID1546198 | Antimicrobial activity against Bacillus subtilis NCIM 2250 after 48 hrs by NCCLS protocol based method | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID608672 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 assessed as zone of inhibition at 1000 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID442421 | Antimicrobial activity against Enterobacter cloacae at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID279889 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 7.8 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID1179267 | Antimicrobial activity against Staphylococcus aureus MTCC 96 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID530769 | Antimicrobial activity against beta-lactamase producing Staphylococcus aureus SH1000 | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID419572 | Antibacterial activity against Pseudomonas putida MTCC 121 at 10 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID278535 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium bifidum R0071 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID144577 | Ability to inhibit 100% growth against Mycobacterium tuberculosis strain no :14029 | 1989 | Journal of medicinal chemistry, Nov, Volume: 32, Issue:11 | Synthesis and antitubercular activity of N-(2-naphthyl)glycine hydrazide analogues. |
| AID424421 | Antibacterial activity against Enterococcus faecalis HIP14333 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID544278 | Antimicrobial activity against Enterococcus faecalis NKH8 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1125782 | Antibacterial activity against Escherichia coli NCIM 2931 assessed as diameter of growth inhibition zone at 10 ug/ml after 20 hrs by agar disc diffusion method | 2014 | European journal of medicinal chemistry, Apr-22, Volume: 77 | New polyfunctional imidazo[4,5-C]pyridine motifs: synthesis, crystal studies, docking studies and antimicrobial evaluation. |
| AID723723 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID544022 | Antimicrobial activity against Psychrobacter frigidicola isolate C712 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID615571 | Antimicrobial activity against Staphylococcus aureus at 100 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID625530 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 741 by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Iodine-catalyzed conjugate addition of indoles onto en-1,4-dione: a novel synthesis of 3-(1-(1H-indol-3-yl)-2-oxo-2-phenylethyl)indolin-2-ones as antibacterial and antifungal agents. |
| AID358865 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 25177 at 5 ug/disk by disk diffusion susceptibility assay | 2001 | Journal of natural products, Mar, Volume: 64, Issue:3 | Pitipeptolides A and B, new cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. |
| AID1463956 | Antimycobacterial activity MDR/XDR against Mycobacterium tuberculosis isolate Praha 1 incubated for 14 days by micromethod | 2017 | Bioorganic & medicinal chemistry, 10-15, Volume: 25, Issue:20 | Development of water-soluble 3,5-dinitrophenyl tetrazole and oxadiazole antitubercular agents. |
| AID637037 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID329355 | Cytotoxicity against human HeLa cells after 24 hrs | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID1179266 | Antimicrobial activity against Enterobacter aerogenes MTCC 111 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID560224 | Antibacterial activity against Salmonella enterica serovar Typhimurium R200 expressing stm3031 gene deletion mutant by CLSI M7-A7 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Outer membrane protein STM3031 (Ail/OmpX-like protein) plays a key role in the ceftriaxone resistance of Salmonella enterica serovar Typhimurium. |
| AID719317 | Antimicrobial activity against Staphylococcus aureus NCIM 5021 by broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID355492 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by twofold serial dilution method | |||
| AID381180 | Antibacterial activity against Staphylococcus aureus after 24 to 72 hrs by disk diffusion method | 1999 | Journal of natural products, Sep, Volume: 62, Issue:9 | Antimicrobial and antitumor activities of mycosporulone. |
| AID419569 | Antibacterial activity against Escherichia coli MTCC 51 at 10 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID515295 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID341095 | Antimicrobial activity against antibiotic-resistant Yersinia pestis mutant on day 10 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Aug, Volume: 51, Issue:8 | Impact of resistance selection and mutant growth fitness on the relative efficacies of streptomycin and levofloxacin for plague therapy. |
| AID561108 | Antibacterial activity against Pasteurella multocida BB1042 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID540179 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis and anti-tubercular and antimicrobial activities of some 2r,4c-diaryl-3-azabicyclo[3.3.1]nonan-9-one N-isonicotinoylhydrazone derivatives. |
| AID404899 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB34 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID424585 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH380 (SCV-52) harboring -1 frameshift mutation at nucleotide 158 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID495752 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow and treated with Cefixime by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID619769 | Antibacterial activity against Staphylococcus aureus RCMB 000106 at 30 mg/ml after 24 hrs by agar well diffusion method | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Design and synthesis of some new thiophene, thienopyrimidine and thienothiadiazine derivatives of antipyrine as potential antimicrobial agents. |
| AID1235643 | Antibacterial activity against Streptococcus pyogenes DSM 11728 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID565743 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID326552 | Antimicrobial activity against Mycobacterium fortuitum V61 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID294737 | Antibacterial activity against Escherichia coli at 0.125% (w/v) concentration after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID456087 | Antibacterial activity against Salmonella Typhimurium ATCC 13311 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1193493 | Thermodynamic equilibrium solubility, log S of the compound in PBS at pH 7.4 at RT after 4 hrs by 96 well plate method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. |
| AID600674 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID278528 | Antimicrobial activity against Bifidobacterium longum ATCC 15708 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID490979 | Antibacterial activity against Bacillus subtilis NCIM 2250 after 24 to 72 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach. |
| AID636969 | Antibacterial activity against Sarcina lutea ATCC 9341 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID424568 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH209 harboring deletion of nucleotide 404-427 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1577327 | Antimycobacterial activity against multi-drug resistant Mycobacterium tuberculosis Praha 1 after 14 days | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. |
| AID537112 | Antimycobacterial activity against Mycobacterium tuberculosis CIP 103471 after 3 to 28 days by twofold dilution method | 2010 | Bioorganic & medicinal chemistry, Nov-15, Volume: 18, Issue:22 | Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin. |
| AID358866 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 25177 at 1 ug/disk by disk diffusion susceptibility assay | 2001 | Journal of natural products, Mar, Volume: 64, Issue:3 | Pitipeptolides A and B, new cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. |
| AID278530 | Antimicrobial activity against Bifidobacterium longum P/N 601377 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID603194 | Antibacterial activity against Klebsiella pneumoniae MTCC 618 by broth microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 21, Issue:13 | Efficient synthesis, structural characterization and anti-microbial activity of chiral aryl boronate esters of 1,2-O-isopropylidene-α-D-xylofuranose. |
| AID1179284 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus MTCC 96 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID637038 | Antibacterial activity against Bacillus idosus B 241 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID1542738 | Antibacterial activity against Escherichia coli ATCC 25922 measured after 18 hrs by broth dilution method | 2019 | Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10 | 6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers. |
| AID279884 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 250 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID448316 | Antibacterial activity against Escherichia coli by broth dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, photochemical E (trans)-->Z (cis) isomerization and antimicrobial activity of 2-chloro-5-methylpyridine-3-olefin derivatives. |
| AID633860 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID561102 | Antibacterial activity against Pasteurella multocida BB1036 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB1005 bearing strA, sul2 genes by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID494347 | Antibacterial activity against Staphylococcus epidermidis by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization and antimicrobial studies of 2-(4-methoxy-phenyl)-5-methyl-4-(2-arylsulfanyl-ethyl)-2,4-dihydro-[1,2,4] triazolo-3-ones and their corresponding sulfones. |
| AID144586 | Ability to inhibit partial growth (50+/-10%) against Mycobacterium tuberculosis strain no: 14029 in Youman's medium | 1989 | Journal of medicinal chemistry, Nov, Volume: 32, Issue:11 | Synthesis and antitubercular activity of N-(2-naphthyl)glycine hydrazide analogues. |
| AID666780 | Antifungal activity against Microbotryum violaceum at 0.05 mg by agar diffusion test | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13 | Bioactive briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. |
| AID565229 | Antimicrobial activity against Mycobacterium chelonae ATCC 35752 harboring pZS01 carrying mspA gene by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID1456557 | Antibacterial activity against Staphylococcus aureus NCIM 5345 assessed as diameter of inhibition zone measured after 20 hrs by agar well diffusion method | |||
| AID587759 | Antimicrobial activity against Mycobacterium ulcerans Mu1059 expressing luxAB from vibrio harveyi infected BALB/c mouse assessed as reduction in foodpad CFU count after 4 weeks | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Using bioluminescence to monitor treatment response in real time in mice with Mycobacterium ulcerans infection. |
| AID1647340 | Inhibition of Mycobacterium tuberculosis H37Rv ATCC 27294 InhA assessed as bacterial growth inhibition after 5 days by microplate alamar blue assay | 2020 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2 | The bioisosteric modification of pyrazinamide derivatives led to potent antitubercular agents: Synthesis via click approach and molecular docking of pyrazine-1,2,3-triazoles. |
| AID338744 | Antimicrobial activity against Staphylococcus aureus after 24 hrs by twofold serial broth dilution technique | |||
| AID587761 | Antimicrobial activity against wild type Mycobacterium ulcerans ATCC 19423 infected BALB/c mouse assessed as delay to time to foodpad swelling | 2011 | Antimicrobial agents and chemotherapy, Jan, Volume: 55, Issue:1 | Using bioluminescence to monitor treatment response in real time in mice with Mycobacterium ulcerans infection. |
| AID633859 | Antibacterial activity against Listeria monocytogenes NCTC 7973 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID1546088 | Antimicrobial activity against Pseudomonas aeruginosa | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID1159123 | Antimicrobial activity against Bacillus subtilis ATCC 6633 for 24 hrs by microdillution method | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells. |
| AID509471 | Antibacterial activity against Staphylococcus aureus at 50 ug/mL | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID737333 | Antimicrobial activity against Klebsiella pneumoniae NCTC 13368 at 750 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID1241215 | Ratio of Kd for 5'-FAM-pre-miR-372 (unknown origin) in presence of 100-fold excess of 15-mer DNA to Kd for 5'-FAM-pre-miR-372 (unknown origin) | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID1435842 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 7 days by resazurin reduction microplate assay | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | New insights into the SAR and drug combination synergy of 2-(quinolin-4-yloxy)acetamides against Mycobacterium tuberculosis. |
| AID245438 | Minimum inhibitory concentration against Bacillus subtilis (Gram-positive) was determined by by broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 2,4,6-tri substituted s-triazines. |
| AID408878 | Antimycobacterial activity against Mycobacterium smegmatis CIP 103599 | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID637028 | Antibacterial activity against Bacillus cereus ATCC 11778 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID166716 | Tested for binding affinity against RNA construct C; n.b. means no observable binding | 2002 | Bioorganic & medicinal chemistry letters, Feb-11, Volume: 12, Issue:3 | Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers. |
| AID1542736 | Antibacterial activity against Staphylococcus aureus ATCC 25923 measured after 18 hrs by broth dilution method | 2019 | Bioorganic & medicinal chemistry, 05-15, Volume: 27, Issue:10 | 6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers. |
| AID370256 | Antimycobacterial activity against Mycobacterium tuberculosis Kurono infected ICR mouse assessed as viable lung bacterial count at 80 mg/kg, po administered once daily measured after 28 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID1653585 | Anti-leprotic activity against Mycobacterium leprae infected in BALB/c weanling mouse assessed as bacteria killing at 150 mg/kg, ip administrated for 60 days and measured after 1 year by Spearman-Karber technique analysis relative to control | 2019 | Bioorganic & medicinal chemistry, 07-01, Volume: 27, Issue:13 | Insights of synthetic analogues of anti-leprosy agents. |
| AID678656 | Antibacterial activity against Staphylococcus aureus ATCC 25923 by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of novel N-acyl substituted quinolin-2(1H)-one derivatives as potential antimicrobial agents. |
| AID144439 | Antibacterial activity was evaluated against Mycobacterium smegmatis | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID70150 | Compound (isolated from leaves of Cistus monspeliensis) was tested for antimicrobial activity against Escherichia coli (ATCC 25922) | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | A simple and rapid method for the differentiation of C-13 manoyl oxide epimers in biologically important samples using GC-MS analysis supported with NMR spectroscopy and computational chemistry results. |
| AID1597388 | Antimicrobial activity against Micrococcus luteus MTCC 11948 incubated for 24 hrs by well diffusion method | 2019 | European journal of medicinal chemistry, Sep-01, Volume: 177 | Synthesis, biological evaluation and computational study of novel isoniazid containing 4H-Pyrimido[2,1-b]benzothiazoles derivatives. |
| AID1186781 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 after 24 hrs by agar well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Sep-01, Volume: 24, Issue:17 | Indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones: synthesis, characterization and evaluation of anticancer and antimicrobial activities. |
| AID1079932 | Highest frequency of moderate liver toxicity observed during clinical trials, expressed as a percentage. [column '% BIOL' in source] | |||
| AID719308 | Antimicrobial activity against Candida albicans NCIM 3471 at 100 ug/mL incubated for 48 hrs by agar disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID445288 | Antibacterial activity against Mycobacterium smegmatis by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID1577331 | Antimycobacterial activity against XDR Mycobacterium tuberculosis Praha 131 after 14 days | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. |
| AID1075577 | Antimicrobial activity against Bacillus subtilis NRS-744 after 18 to 24 hrs by microbroth dilution method | 2014 | European journal of medicinal chemistry, Mar-03, Volume: 74 | Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents. |
| AID245008 | In vitro minimum inhibitory concentration of compound against Mycobacterium smegmatis MTCC 006 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2 | Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones. |
| AID608671 | Antibacterial activity against Clostridium perfringens assessed as zone of inhibition at 500 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID320707 | Inhibition of PAD4 measured by slope plot of Lineweaver-Burke analyses | 2008 | Bioorganic & medicinal chemistry, Jan-15, Volume: 16, Issue:2 | Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors. |
| AID424830 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH417 harboring -1 frameshift mutation at nucleotide 422 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID644167 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1201576 | Antibacterial activity against Staphylococcus aureus at 1 mg/ml incubated for 18 hrs by well plate technique | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. |
| AID428869 | Antibacterial activity against Escherichia coli isolate ARS3 carrying pARS3 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID1104311 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID574581 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 625 obtained from sputum of patient at 1 ug/ml by Bactec MGIT960 modified proportion method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID588211 | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | 2010 | Chemical research in toxicology, Jan, Volume: 23, Issue:1 | Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. |
| AID585420 | Antimicrobial activity against oqxAB positive Escherichia coli C600 W191-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID582763 | Antimicrobial activity against eaeA positive verocytotoxin-producing non-O157 Escherichia coli isolates obtained from human assessed as percentage of resistant isolates | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Antimicrobial resistance testing of verocytotoxin-producing Escherichia coli and first description of TEM-52 extended-spectrum β-lactamase in serogroup O26. |
| AID601248 | Antibacterial activity against Staphylococcus aureus assessed as 99.5% bacterial killing using 1 x 10'4 CFU/ml inoculum after 72 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID245296 | In vitro minimum inhibitory concentration of compound against Methicillin-sensitive Staphylococcus aureus ATCC 29213 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2 | Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones. |
| AID429092 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolates from tuberculosis patient assessed as percent sensitive isolates at 4 ug/ml by absolute-concentration method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Prevalence of and molecular basis for tuberculosis drug resistance in the Republic of Georgia: validation of a QIAplex system for detection of drug resistance-related mutations. |
| AID733708 | Antibacterial activity against methicillin-resistant Staphylococcus aureus at 1 mg/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID774297 | Antimycobacterial activity against isoniazid-resistant Mycobacterium tuberculosis ATCC 35822 | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID565751 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID442407 | Antimicrobial activity against Listeria monocytogenes at 10 ug/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID530758 | Induction of PsgtB::lacZ gene expression in Staphylococcus aureus SH1000 at 3 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID1296383 | Antimycobacterial activity against multi drug resistant Mycobacterium tuberculosis 234/2005 after 14 days by microdilution method | 2016 | Journal of medicinal chemistry, Mar-24, Volume: 59, Issue:6 | Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis. |
| AID424609 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible wild type Staphylococcus aureus 8325-4 clinical isolate after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID495751 | Antimicrobial activity against Escherichia coli J5 transconjugants expressing beta lactamase CTX-M-9 isolated from human flora associated C3H rat infected with Salmonella enterica serotype Virchow by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID278527 | Antimicrobial activity against Bifidobacterium longum ATCC 15707 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID442410 | Antimicrobial activity against Staphylococcus aureus at 1 umol/disk after 24 hrs by disk diffusion assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID534419 | Antibacterial activity against Mycobacterium bovis BCG-Connaught | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics. |
| AID737334 | Antimicrobial activity against Klebsiella pneumoniae NCTC 13368 at 1000 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID563502 | Antimicrobial activity against cetylpyridinium chloride-sensitive Serratia marcescens 71 by broth dilution method | 2009 | Antimicrobial agents and chemotherapy, Dec, Volume: 53, Issue:12 | Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens. |
| AID1241209 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID1201578 | Antibacterial activity against Pseudomonas aeruginosa at 1 mg/ml incubated for 18 hrs by well plate technique | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. |
| AID774608 | Antimicrobial activity against Mycobacterium intracellulare | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Synthesis and antimycobacterial activity of analogues of the bioactive natural products sampangine and cleistopholine. |
| AID279869 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 31.3 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID618738 | Antimicrobial activity against Mycobacterium tuberculosis H37Rv after 11 days using [14]C labeled palmitic acid as substrate by radiometric Bactec 460TB method | 2011 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 21, Issue:18 | Synthesis and biological evaluation of substituted 4-arylthiazol-2-amino derivatives as potent growth inhibitors of replicating Mycobacterium tuberculosis H₃₇Rv. |
| AID1125788 | Antibacterial activity against Bacillus cereus NCIM 2155 assessed as diameter of growth inhibition zone at 10 ug/ml after 20 hrs by agar disc diffusion method | 2014 | European journal of medicinal chemistry, Apr-22, Volume: 77 | New polyfunctional imidazo[4,5-C]pyridine motifs: synthesis, crystal studies, docking studies and antimicrobial evaluation. |
| AID278561 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium breve ATCC 15700 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID382582 | Antibacterial activity against Vibrio cholerae assessed as diameter of inhibition zone at 1.0% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID1179571 | Antifungal activity against fluconazole-resistant Candida albicans at 100 ug/well after 24 hrs by well diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives. |
| AID1247081 | Antibacterial activity against Shigella flexneri assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID1596676 | Antibacterial activity against Enterobacter cloacae clinical isolate after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID428871 | Antibacterial activity against Escherichia coli CSH-2 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID464208 | Antibacterial activity against Bacillus subtilis NCIM 2250 after 24 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3 | Synthesis, in vitro antibacterial and antifungal evaluations of new alpha-hydroxyphosphonate and new alpha-acetoxyphosphonate derivatives of tetrazolo [1, 5-a] quinoline. |
| AID1565881 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition measured after 24 hrs by two-fold broth dilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | Design, synthesis and biological evaluation of novel diazaspiro[4.5]decan-1-one derivatives as potential chitin synthase inhibitors and antifungal agents. |
| AID515244 | Antifungal activity against Candida albicans MTCC 227 at 50 ug/ml after 48 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Anti-tubercular agents. Part 5: synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners. |
| AID424420 | Antibacterial activity against vancomycin-resistant Staphylococcus aureus HIP14300 isolated from patients foot wound by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID775491 | Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay | 2013 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 23, Issue:21 | Synthesis, characterization and in vitro biological evaluation of some novel 1,3,5-triazine-Schiff base conjugates as potential antimycobacterial agents. |
| AID382581 | Antibacterial activity against Pseudomonas aeruginosa assessed as diameter of inhibition zone at 1.0% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID1079939 | Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source] | |||
| AID530286 | Antimicrobial activity against PR-39-resistant Salmonella enterica serovar Typhimurium LT2 DA10899 harboring Q179Stop mutant gene by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID1647341 | Antibacterial activity against Escherichia coli by dilution assay | 2020 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 30, Issue:2 | The bioisosteric modification of pyrazinamide derivatives led to potent antitubercular agents: Synthesis via click approach and molecular docking of pyrazine-1,2,3-triazoles. |
| AID601602 | Antibacterial activity against Kocuria sp. isolate Fs24 at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID355886 | Antimicrobial activity against Escherichia coli ATCC 35218 after 36 hrs under aerobic condition by microdilution method | 2003 | Journal of natural products, May, Volume: 66, Issue:5 | Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity. |
| AID442382 | Antibacterial activity against Bacillus subtilis PTCC 1365 at 10 ug/ml after 24 hrs by disk diffusion sensitivity assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Molecular iodine promoted synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as potential antibacterial agents. |
| AID625288 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for jaundice | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID442380 | Antibacterial activity against Pseudomonas aeruginosa PTCC 1431 at 10 ug/ml after 24 hrs by disk diffusion sensitivity assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Molecular iodine promoted synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as potential antibacterial agents. |
| AID336090 | Antimicrobial activity against Staphylococcus aureus NIH B311 by twofold serial macrobroth dilution assay | 1993 | Journal of natural products, Nov, Volume: 56, Issue:11 | Antimicrobial compounds from Petalostemum purpureum. |
| AID1179274 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 741 at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID279888 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 15.6 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID534828 | Antimicrobial activity against kanamycin-resistant Campylobacter fetus subsp. fetus CA76 harboring deletion in ant(6)-Ib::pCA76 in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID424348 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH202 harboring CTG start codon at nucleotide 1 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID633948 | Antibacterial activity against Escherichia coli ATCC 35210 incubated for 24 hrs followed by serial sub-cultivation for 24 hrs by microdilution | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID1245990 | Antimicrobial activity against Escherichia coli after 24 hrs by spectrophotometry | 2015 | Journal of medicinal chemistry, Jan-22, Volume: 58, Issue:2 | Antimicrobial peptides with potential for biofilm eradication: synthesis and structure activity relationship studies of battacin peptides. |
| AID530546 | Induction of PtcaA::lacZ gene expression in Staphylococcus aureus SH1000 at 3 ug/ml after 2 hrs by beta-galactosidase reporter gene assay relative to untreated control | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Staphylococcus aureus cell wall stress stimulon gene-lacZ fusion strains: potential for use in screening for cell wall-active antimicrobials. |
| AID534421 | Antibacterial activity against Mycobacterium bovis BCG-Denmark | 2009 | Antimicrobial agents and chemotherapy, Jan, Volume: 53, Issue:1 | Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics. |
| AID1596678 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID637026 | Antibacterial activity against Bacillus megaterium NRRL 1353895 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID278554 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium longum R0175 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID279876 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 125 uM promazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID1546644 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 assessed as diameter of zone of inhibition at 200 ug/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID1201597 | Antibacterial activity against Streptomyces scabiei CGMCC4.7610246 assessed as growth inhibition after 36 hrs by turbidimetric analysis | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit gram-positive bacteria growth by regulating metabolism and virulence genes expression. |
| AID294759 | Antibacterial activity against Mycobacterium tuberculosis H37Rv after 2 weeks by broth dilution method | 2007 | Bioorganic & medicinal chemistry letters, May-01, Volume: 17, Issue:9 | Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus. |
| AID696343 | Antibacterial activity against Staphylococcus aureus ATCC 25930 after 24 hrs by two fold serial dilution method | 2012 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 22, Issue:21 | Design, synthesis, spectral and biological evaluation of novel 1-allyl substituted 2,6-diphenylpiperidin-4-ones and its derivatives of oximes/oxime ethers. |
| AID1274482 | Antibacterial activity against Escherichia coli JM 109 after 24 hrs by two-fold serial dilution method | 2016 | European journal of medicinal chemistry, Jan-27, Volume: 108 | Synthesis and biological evaluation of novel phosphoramidate derivatives of coumarin as chitin synthase inhibitors and antifungal agents. |
| AID424582 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH331 (SCV-3) harboring Arg659His mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1324372 | Antibacterial activity against Escherichia coli after 24 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | Novel substituted hydrazono indolo[2,1-b]quinazoline-6,12-dione analogues as cytostatic agents: Synthesis, crystal structure, biological evaluation and molecular docking studies. |
| AID277068 | Antibacterial activity against Escherichia coli by measuring zone of inhibition at 30 ug after 24 hrs | 2006 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 16, Issue:24 | Synthesis of antimicrobial 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines. |
| AID1061251 | Antimicrobial activity against Escherichia coli at 0.5 mg/ml by well plate method | 2014 | European journal of medicinal chemistry, Jan, Volume: 71 | Synthesis and biological evaluation of novel substituted 1,3,4-thiadiazole and 2,6-di aryl substituted imidazo [2,1-b] [1,3,4] thiadiazole derivatives. |
| AID1253865 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 5 days by microplate alamar blue assay | 2015 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 25, Issue:22 | Discovery of the disubstituted oxazole analogues as a novel class anti-tuberculotic agents against MDR- and XDR-MTB. |
| AID532990 | Antibacterial activity against Klebsiella pneumoniae NCIM 2883 assessed as growth inhibition in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1179283 | Antimicrobial activity against Proteus vulgaris MTCC 1771 after 24 hrs by two fold dilution method | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID355891 | Antimicrobial activity against Bacillus cereus isolate after 36 hrs under aerobic condition by microdilution method | 2003 | Journal of natural products, May, Volume: 66, Issue:5 | Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity. |
| AID496399 | Antibacterial activity against azide-resistant Escherichia coli J53 TET2 transconjugant with qnrVC3 gene expressing Vibrio cholerae 59 strain | 2010 | Antimicrobial agents and chemotherapy, Feb, Volume: 54, Issue:2 | Transferable quinolone resistance in Vibrio cholerae. |
| AID456351 | Antibacterial activity against Bacillus anthracis after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID544017 | Antimicrobial activity against Enterococcus sulfureus isolate PGS61 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID494349 | Antibacterial activity against Pseudomonas aeruginosa by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization and antimicrobial studies of 2-(4-methoxy-phenyl)-5-methyl-4-(2-arylsulfanyl-ethyl)-2,4-dihydro-[1,2,4] triazolo-3-ones and their corresponding sulfones. |
| AID278526 | Antimicrobial activity against Bifidobacterium infantis ATCC 15697 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID424606 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH330 (SCV-2) harboring -1 frameshift mutation at nucleotide 423 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1224517 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 234/2005 after 7 days by micromethod | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | 1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. |
| AID540211 | Fraction unbound in human after iv administration | 2008 | Drug metabolism and disposition: the biological fate of chemicals, Jul, Volume: 36, Issue:7 | Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. |
| AID442480 | Antibacterial activity against Escherichia coli MTCC 443 by broth dilution method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Click chemistry: studies on the synthesis of novel fluorous tagged triazol-4-yl substituted quinazoline derivatives and their biological evaluation--theoretical and experimental validation. |
| AID1105383 | Antibacterial activity against Erwinia chrysanthemi ITCC B-40 assessed as as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID509472 | Antibacterial activity against Staphylococcus aureus at 100 ug/mL | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID637086 | Antibacterial activity against Escherichia coli ATCC 8739 at 1 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID719310 | Antimicrobial activity against Pseudomonas aeruginosa NCIM 5029 at 10 ug/disc incubated for 24 hrs by agar disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID541857 | Antimicrobial activity against Escherichia coli ATCC 29522 carrying Edwardsiella ictaluri pM07-1 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID532981 | Antibacterial activity against Escherichia coli DH5alpha | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1104319 | Antibacterial activity against Proteus mirabilis at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID283222 | Antimicrobial activity against Escherichia coli XL1-Blue [pBluescript 2 SK(+) | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. |
| AID733710 | Antibacterial activity against Enterobacter aerogenes MTCC 111 at 1 mg/disc after 24 hrs by disc diffusion method | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID544275 | Antimicrobial activity against Enterococcus faecalis NKH5 harboring pMG2200-like plasmid after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID334155 | Antimicrobial activity against Staphylococcus aureus at 10 ug by antimicrobial disk assay | 1997 | Journal of natural products, Nov, Volume: 60, Issue:11 | New phomopsolides from a Penicillium sp. |
| AID599450 | Antitubercular activity against Mycobacterium tuberculosis H37Rv after 24 hrs by BACTEC radiometric susceptibility assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | 2,3-dideoxy hex-2-enopyranosid-4-uloses as promising new anti-tubercular agents: design, synthesis, biological evaluation and SAR studies. |
| AID1272601 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by broth microdilution technique | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. |
| AID1247080 | Antibacterial activity against Klebsiella pneumoniae assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID1476363 | Antitubercular activity against capreomycin resistant Mycobacterium tuberculosis H37Rv after 24 hrs by MABA method | 2017 | Journal of medicinal chemistry, 10-26, Volume: 60, Issue:20 | Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity. |
| AID442381 | Antibacterial activity against Staphylococcus aureus PTCC 1074 at 10 ug/ml after 24 hrs by disk diffusion sensitivity assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Molecular iodine promoted synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as potential antibacterial agents. |
| AID495749 | Antimicrobial activity against Salmonella enterica serotype Virchow 3464b by Etest method | 2010 | Antimicrobial agents and chemotherapy, Jan, Volume: 54, Issue:1 | Transfer of plasmid-mediated CTX-M-9 from Salmonella enterica serotype Virchow to Enterobacteriaceae in human flora-associated rats treated with cefixime. |
| AID382573 | Antibacterial activity against Pseudomonas aeruginosa assessed as diameter of inhibition zone at 0.25% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID585426 | Antimicrobial activity against oqxAB positive Escherichia coli C600 X1B1-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID575170 | Inhibition of acrAB AcrAB-TolC-mediated Nile Red efflux in Escherichia coli K-12 3-AG100 overexpressing acrAB AcrAB-TolC assessed as time needed for 50% efflux after energization with 50 mM glucose at 200 uM by spectrofluorometric assay | 2010 | Antimicrobial agents and chemotherapy, Sep, Volume: 54, Issue:9 | Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. |
| AID590141 | Antitubercular activity against Mycobacterium tuberculosis H37Rv by LORA assay | 2011 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 21, Issue:7 | Novel thiolactone-isatin hybrids as potential antimalarial and antitubercular agents. |
| AID575680 | Antibacterial activity against Listeria monocytogenes isolated from humans harboring putative ribosomal mutation | 2010 | Antimicrobial agents and chemotherapy, Jun, Volume: 54, Issue:6 | Antimicrobial resistance of Listeria monocytogenes strains isolated from humans in France. |
| AID404897 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB30 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID275054 | Antibacterial activity against Escherichia coli W3110 | 2006 | Journal of medicinal chemistry, Dec-14, Volume: 49, Issue:25 | Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin. |
| AID1247075 | Antibacterial activity against methicillin-resistant Staphylococcus aureus assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID723719 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID544279 | Antimicrobial activity against Enterococcus faecalis NKH9 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID1577337 | Antimycobacterial activity against multi-drug resistant Mycobacterium tuberculosis 7357/1998 after 21 days | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. |
| AID445285 | Antibacterial activity against Mycobacterium bovis BCG str. Tokyo 172 by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID445286 | Antibacterial activity against Mycobacterium avium 724S by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID206193 | Tested for the antimicrobial activity as minimum inhibitory concentration against Staphylococcus aureus ATCC 6538 | 2002 | Bioorganic & medicinal chemistry letters, Mar-11, Volume: 12, Issue:5 | New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation. |
| AID293801 | Antibacterial activity against Escherichia coli | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives. |
| AID1156888 | Antimicrobial activity against Escherichia coli ATCC 25922 after 24 hrs by NCCLS M7-A5 method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID1653588 | Anti-leprotic activity against Mycobacterium leprae infected in BALB/c weanling mouse assessed as bacteria killing at 150 mg/kg, ip administrated cotreated with 0.0001% dietary dapsone for 60 days and measured after 1 year by Spearman-Karber technique ana | 2019 | Bioorganic & medicinal chemistry, 07-01, Volume: 27, Issue:13 | Insights of synthetic analogues of anti-leprosy agents. |
| AID625531 | Antimicrobial activity against Klebsiella pneumoniae MTCC 618 by broth dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Iodine-catalyzed conjugate addition of indoles onto en-1,4-dione: a novel synthesis of 3-(1-(1H-indol-3-yl)-2-oxo-2-phenylethyl)indolin-2-ones as antibacterial and antifungal agents. |
| AID1577335 | Antimycobacterial activity against multi-drug resistant Mycobacterium tuberculosis 234/2005 after 14 days | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. |
| AID456082 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID540184 | Antibacterial activity against Pseudomonas aeruginosa NCIM 2035 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis and anti-tubercular and antimicrobial activities of some 2r,4c-diaryl-3-azabicyclo[3.3.1]nonan-9-one N-isonicotinoylhydrazone derivatives. |
| AID600673 | Antibacterial activity against Micrococcus flavus ATCC 10240 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID585431 | Antimicrobial activity against oqxAB positive Escherichia coli C600 D83-T transconjugant by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID1104321 | Antibacterial activity against Staphylococcus aureus ATCC 6538 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID532989 | Antibacterial activity against Klebsiella aerogenes NCIM 2281 in presence of 10 mM N-Acetylcysteine | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID279885 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 125 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID279870 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 15.6 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID1565882 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as growth inhibition measured after 24 hrs by two-fold broth dilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | Design, synthesis and biological evaluation of novel diazaspiro[4.5]decan-1-one derivatives as potential chitin synthase inhibitors and antifungal agents. |
| AID1443992 | Total Cmax in human administered as single dose | 2014 | Hepatology (Baltimore, Md.), Sep, Volume: 60, Issue:3 | Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. |
| AID1255674 | Antibacterial activity against Staphylococcus aureus ATCC 6538P after 24 to 48 hrs | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID1555429 | Antibacterial activity against Proteus vulgaris assessed as diameter of zone of inhibition at 10 ug/disc by disc diffusion method | 2019 | European journal of medicinal chemistry, Aug-15, Volume: 176 | Phytochemical and pharmacological attributes of piperine: A bioactive ingredient of black pepper. |
| AID1143265 | Antimycobacterial activity against Mycobacterium tuberculosis D-211 assessed as growth inhibition after 2 to 3 weeks by turbidometry | 2014 | Journal of medicinal chemistry, Jun-12, Volume: 57, Issue:11 | Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. |
| AID434664 | Antibacterial activity against Escherichia coli ATCC 25835 after 24 hrs by twofold serial dilution method | 2009 | Bioorganic & medicinal chemistry letters, May-15, Volume: 19, Issue:10 | Design, synthesis and biological evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-1,3-thiazolidin-4-ones as a new class of antimicrobial agents. |
| AID615482 | Antimicrobial activity against Bacillus subtilis at 50 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID532988 | Antibacterial activity against Klebsiella aerogenes NCIM 2281 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID424601 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH378 (SCV-50) harboring -1 frameshift mutation at nucleotide 221 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID456074 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID544020 | Antimicrobial activity against Psychrobacter ikaite isolate C20 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID490980 | Antibacterial activity against Escherichia coli ATCC 25922 after 24 to 72 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach. |
| AID278525 | Antimicrobial activity against Bifidobacterium breve ATCC 15700 | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID1247093 | Antibacterial activity against Micrococcus luteus after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID565230 | Antimicrobial activity against Mycobacterium chelonae 9917 by resazurine microtiter assay | 2009 | Antimicrobial agents and chemotherapy, Sep, Volume: 53, Issue:9 | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. |
| AID203464 | Antibacterial activity was evaluated against staphylococcus | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID1597386 | Antimicrobial activity against Escherichia coli MTCC 1610 incubated for 24 hrs by well diffusion method | 2019 | European journal of medicinal chemistry, Sep-01, Volume: 177 | Synthesis, biological evaluation and computational study of novel isoniazid containing 4H-Pyrimido[2,1-b]benzothiazoles derivatives. |
| AID1174112 | Antimycobacterial activity against isoniazid, rifampin-resistant Mycobacterium tuberculosis after 7 days by microplate Alamar blue assay | 2015 | European journal of medicinal chemistry, Jan-07, Volume: 89 | Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis. |
| AID445334 | Selectivity for Mycobacterium tuberculosis H37Rv over human MRC5 cells | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID1454343 | Antibacterial activity Escherichia coli MTCC 443 by agar well method | 2017 | Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15 | Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides. |
| AID1235641 | Antibacterial activity against Bacillus subtilis DSM 1088 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID1303894 | Antibacterial activity against multidrug resistant Acinetobacter baumannii 2208 (ATCC 19606) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | 2016 | Bioorganic & medicinal chemistry letters, 07-01, Volume: 26, Issue:13 | GroEL/ES inhibitors as potential antibiotics. |
| AID376319 | Antibacterial activity against Pseudomonas tolaasii after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID1566495 | Inhibition of biotinylated pre-let-7d (unknown origin) maturation at 1 mM preincubated for 15 mins followed by Pre-let-7d addition and measured after 5 hrs by cat-ELCCA | 2019 | ACS medicinal chemistry letters, May-09, Volume: 10, Issue:5 | Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition. |
| AID382580 | Antibacterial activity against Staphylococcus aureus assessed as diameter of inhibition zone at 1.0% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID1546650 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 assessed as reduction in microbial growth after 24 hrs by CLSI based microdilution method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID1201596 | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as growth inhibition after 24 hrs by turbidimetric analysis | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit gram-positive bacteria growth by regulating metabolism and virulence genes expression. |
| AID429096 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolates from tuberculosis patient assessed as percent specific isolates at 4 ug/ml by absolute-concentration method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Prevalence of and molecular basis for tuberculosis drug resistance in the Republic of Georgia: validation of a QIAplex system for detection of drug resistance-related mutations. |
| AID562389 | Antimicrobial activity against Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID326545 | Antimicrobial activity against Mycobacterium abscessus R54 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID244872 | In vitro minimum inhibitory concentration against Enterococcus faecalis ATCC 29212 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2 | Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones. |
| AID1104312 | Antibacterial activity against Escherichia coli ATCC 35210 at 48 degC measured after 72 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1324369 | Antibacterial activity against Staphylococcus aureus after 24 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | Novel substituted hydrazono indolo[2,1-b]quinazoline-6,12-dione analogues as cytostatic agents: Synthesis, crystal structure, biological evaluation and molecular docking studies. |
| AID1456562 | Antibacterial activity against Escherichia coli NCIM 2931 assessed as diameter of inhibition zone measured after 20 hrs by agar well diffusion method | |||
| AID245519 | Minimum inhibitory concentration against Chromobacterium violaceum (Gram-negative) was determined by broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 2,4,6-tri substituted s-triazines. |
| AID532956 | Antimicrobial activity against Mycobacterium tuberculosis ATCC 35802 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | In vitro antituberculosis activities of ACH-702, a novel isothiazoloquinolone, against quinolone-susceptible and quinolone-resistant isolates. |
| AID279882 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 1000 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID1597384 | Antimicrobial activity against Enterobacter aerogenes MTCC 8558 incubated for 24 hrs by well diffusion method | 2019 | European journal of medicinal chemistry, Sep-01, Volume: 177 | Synthesis, biological evaluation and computational study of novel isoniazid containing 4H-Pyrimido[2,1-b]benzothiazoles derivatives. |
| AID1456593 | Inhibition of Mycobacterium tuberculosis H37Rv enoyl ACP reductase assessed as reduction in bacterial growth after 5 days by microplate alamar blue assay | 2017 | Bioorganic & medicinal chemistry letters, 05-15, Volume: 27, Issue:10 | Novel quinoxalinyl chalcone hybrid scaffolds as enoyl ACP reductase inhibitors: Synthesis, molecular docking and biological evaluation. |
| AID445210 | Antituberculosis activity against Mycobacterium tuberculosis H37Rv by broth dilution method | 2009 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 19, Issue:22 | Synthesis of new sugar derivatives and evaluation of their antibacterial activities against Mycobacterium tuberculosis. |
| AID1443988 | Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-taurocholate uptake in to vesicles after 5 mins by microbeta filtration method | 2014 | Hepatology (Baltimore, Md.), Sep, Volume: 60, Issue:3 | Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. |
| AID278539 | Antimicrobial activity against 60 min 1 M HCl-stressed Bifidobacterium infantis ATCC 15697 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID419577 | Antibacterial activity against Escherichia coli MTCC 51 after 24 hrs | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID1330850 | Antimycobacterial activity against Mycobacterium smegmatis MC2 155 measured after 48 hrs by resazurin dye-based MABA method | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | FtsZ inhibition and redox modulation with one chemical scaffold: Potential use of dihydroquinolines against mycobacteria. |
| AID1487412 | Antibacterial activity against Staphylococcus intermedius isolate 1051997 after 24 hrs by broth microdilution method | 2017 | Bioorganic & medicinal chemistry, 08-15, Volume: 25, Issue:16 | Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase. |
| AID302000 | Selectivity index, ratio of IC50 for Vero cells to MIC of Mycobacterial tuberculosis H37Rv | 2007 | Bioorganic & medicinal chemistry, Dec-15, Volume: 15, Issue:24 | Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase. |
| AID434663 | Antibacterial activity against Salmonella typhi ATCC 24915 after 24 hrs by twofold serial dilution method | 2009 | Bioorganic & medicinal chemistry letters, May-15, Volume: 19, Issue:10 | Design, synthesis and biological evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-1,3-thiazolidin-4-ones as a new class of antimicrobial agents. |
| AID601172 | Antibacterial activity against Escherichia coli using 1 x 10'4 CFU/ml inoculum after 24 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID1545441 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as diameter of zone inhibition at 30 ug/ml | 2019 | Bioorganic & medicinal chemistry, 04-01, Volume: 27, Issue:7 | Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances. |
| AID370072 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 35837 after 14 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID332803 | Antibacterial activity against Escherichia coli at 10 mg/10 ml dimethylformamide | |||
| AID370074 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 35812 after 14 days | 2006 | PLoS medicine, Nov, Volume: 3, Issue:11 | OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. |
| AID1276594 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 16 hrs by two-fold microdillution method | 2016 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 26, Issue:2 | Naphtho[1',2':4,5]imidazo[1,2-a]pyridine-5,6-diones: Synthesis, enzymatic reduction and cytotoxic activity. |
| AID765105 | Bacteriostatic activity against rifampicin, isoniazid, streptomycin, ethambutol and pyrazinamide-resistant Mycobacterium tuberculosis MS-115 assessed as growth inhibition at 2 to 200 ug/mL relative to control | 2013 | Bioorganic & medicinal chemistry, Sep-01, Volume: 21, Issue:17 | Inhibition of Mycobacterium tuberculosis strains H37Rv and MDR MS-115 by a new set of C5 modified pyrimidine nucleosides. |
| AID569262 | Antimicrobial activity against Escherichia coli DH5alpha | 2011 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3 | Synthesis and evaluation of anti-tubercular activity of new dithiocarbamate sugar derivatives. |
| AID424336 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH207 harboring Thr385Asn mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID375078 | Binding affinity to small bacterial subunit RNA | 2009 | Journal of medicinal chemistry, Jun-25, Volume: 52, Issue:12 | Design and implementation of an ribonucleic acid (RNA) directed fragment library. |
| AID1156884 | Antimicrobial activity against Candida tropicalis MTCC 184 at 100 ug/disc after 48 hrs by agar cup plate method | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis and biological evaluation of novel N-aryl maleimide derivatives clubbed with α-hydroxyphosphonates. |
| AID404097 | Antimicrobial activity against Micrococcus flavus ATCC 10240 by microdilution method | 2005 | Journal of natural products, Sep, Volume: 68, Issue:9 | Sesquiterpene lactones from Centaurea spinosa and their antibacterial and cytotoxic activities. |
| AID1079936 | Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source] | |||
| AID747756 | Antibacterial activity against Klebsiella pneumoniae after 24 hrs by broth dilution method | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID375853 | Antibacterial activity against Shigella sp. after 48 hrs by agar well diffusion method | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13 | Synthesis and antibacterial activity of some novel imidazole-based dicationic quinolinophanes. |
| AID1079933 | Acute liver toxicity defined via clinical observations and clear clinical-chemistry results: serum ALT or AST activity > 6 N or serum alkaline phosphatases activity > 1.7 N. This category includes cytolytic, choleostatic and mixed liver toxicity. Value is | |||
| AID1255670 | Antibacterial activity against Salmonella abony NCTC 6017 assessed as growth inhibition at 100 ug/ml after 8 to 24 hrs by agar well diffusion method | 2015 | European journal of medicinal chemistry, Oct-20, Volume: 103 | Synthesis, characterization, crystal structure determination and biological screening of novel N-1 and C5 alkyl substituted scaffolds of pyrimidine. |
| AID329354 | Ratio of MIC90 for Yersinia pestis KIM6-2082.1+ in iron rich PMH-D medium to MIC90 for Yersinia pestis KIM6-2082.1+ in presence of iron limiting PMH-D medium | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID294739 | Antibacterial activity against Escherichia coli at 0.5% (w/v) concentration by after 24 hrs by disc diffusion method | 2007 | European journal of medicinal chemistry, Aug, Volume: 42, Issue:8 | Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction. |
| AID1577333 | Antimycobacterial activity against multi-drug resistant Mycobacterium tuberculosis 9449/2007 after 21 days | 2019 | Journal of medicinal chemistry, 09-12, Volume: 62, Issue:17 | Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2'-Oxidase. |
| AID620346 | Antibacterial activity against Staphylococcus aureus RCMB 000106 at 30 ug/ml after 24 hrs by diffusion agar technique | 2011 | European journal of medicinal chemistry, Oct, Volume: 46, Issue:10 | Synthesis and anti-microbial activity of some 1- substituted amino-4,6-dimethyl-2-oxo-pyridine-3-carbonitrile derivatives. |
| AID144444 | Antibacterial activity against Mycobacterium smegmatis CIP 103599. | 1998 | Bioorganic & medicinal chemistry letters, Oct-20, Volume: 8, Issue:20 | Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis. |
| AID419565 | Antibacterial activity against Bacillus subtilis MTCC 8509 at 100 ug/mL by agar well diffusion method | 2009 | European journal of medicinal chemistry, May, Volume: 44, Issue:5 | Organoiodine (III)-mediated synthesis of 3-aryl/heteroaryl-5,7-dimethyl-1,2,4-triazolo[4,3-c]pyrimidines as antibacterial agents. |
| AID143870 | Antibacterial activity was evaluated against MAC (Mycobacterium Avium Complex ) | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID648375 | Antibacterial activity against Micrococcus luteus after 24 hrs by twofold serial dilution method | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID637020 | Antibacterial activity against Micrococcus luteus ATCC 9631 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID424572 | Antibacterial activity against kanamycin-susceptible wild type Staphylococcus aureus AH001 after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1156673 | Antimicrobial activity against Staphylococcus epidermidis MTCC 3615 assessed as zone of inhibition at 1 mg/disc after 24 hrs incubation by disc diffusion assay | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID1179573 | Antifungal activity against fluconazole-resistant Candida albicans by NCCLS method | 2014 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 24, Issue:15 | Synthesis and SAR study of novel anticancer and antimicrobial naphthoquinone amide derivatives. |
| AID1570729 | Antimicrobial activity against Enterococcus faecalis ATCC 29212 at 300 ug/disk incubated for 20 +/- 4 hrs by agar disk diffusion method | 2019 | Bioorganic & medicinal chemistry, 11-01, Volume: 27, Issue:21 | Synthesis and evaluation of 1,3,4-oxadiazole derivatives for development as broad-spectrum antibiotics. |
| AID1241208 | Inhibition of pre-miR-21 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID236835 | Maximum Frel value for binding to 3'-Fl-AM1A-Rhd in Bacillus subtilis tyr | 2005 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 15, Issue:8 | Fluorescence resonance energy transfer studies of aminoglycoside binding to a T box antiterminator RNA. |
| AID1204388 | Antibacterial activity against Staphylococcus aureus assessed as growth inhibition at 100 umol/L after 8 hrs by ELISA plate reader analysis relative to control | 2015 | European journal of medicinal chemistry, Jun-05, Volume: 97 | Benzaldehyde Schiff bases regulation to the metabolism, hemolysis, and virulence genes expression in vitro and their structure-microbicidal activity relationship. |
| AID424600 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH384 (SCV-56) harboring -1 frameshift mutation at nucleotide 221 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID326547 | Antimicrobial activity against Mycobacterium abscessus R65 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID294552 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 at 10 ug by disk diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Rapid synthesis of sulfone derivatives as potential anti-infectious agents. |
| AID1170145 | Antimicrobial activity against Acinetobacter sp. BD4 DSM 586 incubated for 24 hrs by disk diffusion method | 2014 | Journal of natural products, Nov-26, Volume: 77, Issue:11 | Antibacterial secondary metabolites from an endophytic fungus, Eupenicillium sp. LG41. |
| AID490975 | Antibacterial activity against Bacillus subtilis NCIM 2250 after 48 hrs by agar cup plate method | 2010 | European journal of medicinal chemistry, Jul, Volume: 45, Issue:7 | Synthesis and biological evaluation of new 2-chloro-3-((4-phenyl-1H-1,2,3-triazol-1-yl)methyl)quinoline derivatives via click chemistry approach. |
| AID206515 | Compound (isolated from leaves of Cistus monspeliensis) was tested for antimicrobial activity against Staphylococcus hominis (ATCC 27844) | 2002 | Bioorganic & medicinal chemistry letters, Dec-16, Volume: 12, Issue:24 | A simple and rapid method for the differentiation of C-13 manoyl oxide epimers in biologically important samples using GC-MS analysis supported with NMR spectroscopy and computational chemistry results. |
| AID424341 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH197 harboring Leu456Phe mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1247076 | Antibacterial activity against Salmonella paratyphi B assessed as growth inhibition at 1 mg/well after 24 hrs by Well method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID594340 | Antimicrobial activity against Proteus vulgaris NCIM 2027/ATCC 13315 at 1000 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID562592 | Antimicrobial activity against Enterococcus faecalis expressing VanB gene clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID561106 | Antibacterial activity against Pasteurella multocida BB1040 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID1272603 | Antibacterial activity against Klebsiella pneumoniae MTCC 109 after 24 hrs by broth microdilution technique | 2016 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 26, Issue:3 | Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases. |
| AID1333275 | Antimycobacterial activity against Mycobacterium smegmatis MC2 155 assessed as inhibition of respiratory ATP synthesis by measuring ATP level at 4 times MIC measured after 6 hrs by luciferase reporter gene assay (Rvb = 152%) | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID448069 | Antibacterial activity against Xanthomonas oryzae at 50 mg/L after 24 hrs by agar well diffusion method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Design, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)quinoline-3-carboxylic acid derivatives. |
| AID283652 | Antibacterial activity against Escherichia coli K12 W3110 in presence of 10 mM ascorbic acid | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID1156684 | Antimicrobial activity against Staphylococcus epidermidis MTCC 3615 assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID1063305 | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as growth inhibition after 16 to 24 hrs by microplate-Alamar Blue assay | 2014 | European journal of medicinal chemistry, Jan-24, Volume: 72 | Design, synthesis and investigation on the structure-activity relationships of N-substituted 2-aminothiazole derivatives as antitubercular agents. |
| AID279900 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 125 uM chlorpromazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID633848 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID631063 | Bactericidal activity against Yersinia pestis KIM6-2082.1+ in PMHD medium at 2 times MIC after 3 days by colony counting | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide-polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID544280 | Antimicrobial activity against Enterococcus faecalis NKH10 harboring pMG2200-like and pMG2201-like plasmids after 24 hrs by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Isolation of VanB-type Enterococcus faecalis strains from nosocomial infections: first report of the isolation and identification of the pheromone-responsive plasmids pMG2200, Encoding VanB-type vancomycin resistance and a Bac41-type bacteriocin, and pMG2 |
| AID715624 | Antibacterial activity against Bacillus subtilis MTCC 441 after 24 hrs by serial dilution method | 2012 | European journal of medicinal chemistry, Nov, Volume: 57 | Synthesis, characterization, biological evaluation and QSAR studies of 11-p-substituted phenyl-12-phenyl-11a,12-dihydro-11H-indeno[2,1-c][1,5]benzothiazepines as potential antimicrobial agents. |
| AID1079938 | Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] | |||
| AID381179 | Antibacterial activity against penicillin-resistant Staphylococcus aureus after 24 to 72 hrs by disk diffusion method | 1999 | Journal of natural products, Sep, Volume: 62, Issue:9 | Antimicrobial and antitumor activities of mycosporulone. |
| AID615475 | Antimicrobial activity against Escherichia coli at 25 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID644164 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 24 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID408871 | Antimycobacterial activity against rifampicin-resistant Mycobacterium tuberculosis | 2008 | Journal of medicinal chemistry, Jun-26, Volume: 51, Issue:12 | 1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings. |
| AID601170 | Antibacterial activity against Bacillus thuringiensis using 1 x 10'4 CFU/ml inoculum after 24 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID1546645 | Antibacterial activity against Klebsiella pneumoniae MTCC 618 assessed as diameter of zone of inhibition at 200 ug/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID442379 | Antibacterial activity against Escherichia coli HB101 BA 7601C at 10 ug/ml after 24 hrs by disk diffusion sensitivity assay | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Molecular iodine promoted synthesis of new pyrazolo[3,4-d]pyrimidine derivatives as potential antibacterial agents. |
| AID278555 | Antimicrobial activity against 90 mins oxgall-stressed Bifidobacterium longum P/N 601377 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID614919 | Antibacterial activity against Bacillus subtilis ATCC 12711 after 24 hrs by broth micro dilution assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9 | Synthesis, antimicrobial evaluation and QSAR analysis of novel nalidixic acid based 1,2,4-triazole derivatives. |
| AID1596682 | Antibacterial activity against Escherichia coli ATCC 35210 after 24 hrs by iodonitrotetrazolium chloride dye based microdilution method | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID509481 | Antibacterial activity against Staphylococcus aureus | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID594327 | Antimicrobial activity against Staphylococcus aureus NCIM 2079/ATCC 6538P at 50 ug/mL after 24 hrs by disc diffusion method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines. |
| AID414458 | Antitubercular activity against replicating form of Mycobacterium tuberculosis H37Rv ATCC 27294 after 7 days by microplate alamar blue assay | 2009 | Journal of medicinal chemistry, Apr-09, Volume: 52, Issue:7 | Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium tuberculosis. |
| AID674382 | Antibacterial activity Staphylococcus aureus ATCC 25923 at 0.5 mg/ml after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 22, Issue:14 | Synthesis of benzofuran based 1,3,5-substituted pyrazole derivatives: as a new class of potent antioxidants and antimicrobials--a novel accost to amend biocompatibility. |
| AID1233490 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as inhibition of visual microbial growth incubated for 24 hrs at 37 degC | 2015 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 25, Issue:14 | Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. |
| AID562595 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates assessed as resistant isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID293803 | Antibacterial activity against Klebsiella pneumoniae | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives. |
| AID615480 | Antimicrobial activity against Pseudomonas aeruginosa at 100 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID442481 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 by broth dilution method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Click chemistry: studies on the synthesis of novel fluorous tagged triazol-4-yl substituted quinazoline derivatives and their biological evaluation--theoretical and experimental validation. |
| AID1546155 | Antimicrobial activity against Escherichia coli assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID1241211 | Binding affinity to 5'-FAM-pre-miR-373 (unknown origin) after 4 hrs by fluorescence assay | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID245356 | Minimum inhibitory concentration against Pseudomonas aeruginosa (Gram-negative) by broth dilution method | 2005 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 15, Issue:4 | Synthesis and antibacterial activity of 2,4,6-tri substituted s-triazines. |
| AID283221 | Antimicrobial activity against Escherichia coli XL1-Blue pPA95S29 | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. |
| AID588210 | Human drug-induced liver injury (DILI) modelling dataset from Ekins et al | 2010 | Drug metabolism and disposition: the biological fate of chemicals, Dec, Volume: 38, Issue:12 | A predictive ligand-based Bayesian model for human drug-induced liver injury. |
| AID515921 | Antibacterial activity against clofazimine-resistant Mycobacterium tuberculosis after 7 days by microplate alamar blue assay | 2010 | Bioorganic & medicinal chemistry, Oct-15, Volume: 18, Issue:20 | Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring. |
| AID424607 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH390 (SCV-62) harboring +1 frameshift mutation at nucleotide 84 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID515321 | Antibacterial activity against Escherichia coli at 50 ug/ml after 24 to 48 hrs by cup-plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Synthesis and biological property of some novel 1,3,4-oxadiazoles. |
| AID1235640 | Antibacterial activity against Escherichia coli DSM 682 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID494346 | Antibacterial activity against Staphylococcus aureus by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization and antimicrobial studies of 2-(4-methoxy-phenyl)-5-methyl-4-(2-arylsulfanyl-ethyl)-2,4-dihydro-[1,2,4] triazolo-3-ones and their corresponding sulfones. |
| AID678660 | Antibacterial activity against Escherichia coli JM 109 by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of novel N-acyl substituted quinolin-2(1H)-one derivatives as potential antimicrobial agents. |
| AID550046 | Antitubercular activity against Mycobacterium tuberculosis H37Rv assessed as inhibition of colonies after 30 days by agar microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 21, Issue:1 | Conventional and microwave assisted synthesis of 2-oxo-4-substituted aryl-azetidine derivatives of benzotriazole: a new class of biological compounds. |
| AID601598 | Antibacterial activity against Bacillus subtilis assessed as diameter of zone of inhibition at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID336087 | Antimicrobial activity against Cryptococcus neoformans ATCC 32264 by twofold serial macrobroth dilution assay | 1993 | Journal of natural products, Nov, Volume: 56, Issue:11 | Antimicrobial compounds from Petalostemum purpureum. |
| AID206394 | Compound was tested for photoinhibition of Staphylococcus aureus(CIP 53156); Sensitive | 1998 | Bioorganic & medicinal chemistry letters, Nov-03, Volume: 8, Issue:21 | Nitroglycosylated meso-arylporphyrins as photoinhibitors of gram positive bacteria. |
| AID544025 | Antimicrobial activity against Acinetobacter calcoaceticus isolate C36 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1247090 | Antibacterial activity against Salmonella paratyphi B after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID1201575 | Antibacterial activity against Escherichia coli at 0.5 mg/ml incubated for 18 hrs by well plate technique | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives. |
| AID143721 | In vitro cytotoxicity against Mycobacterium avium (CIP 103317) was determined | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12 | N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480. |
| AID448314 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, photochemical E (trans)-->Z (cis) isomerization and antimicrobial activity of 2-chloro-5-methylpyridine-3-olefin derivatives. |
| AID1333139 | Induction of membrane disruption in Mycobacterium smegmatis MC2 155 assessed as increased cytoplasmic membrane permeability at 60 uM up to 3 hrs by Sytox green uptake assay | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID278566 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium longum P/N 601377 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID206096 | Antibacterial activity was evaluated against streptococcus. | 1999 | Journal of medicinal chemistry, Jul-15, Volume: 42, Issue:14 | Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. |
| AID770972 | Antibacterial activity against Staphylococcus epidermidis MTCC 435 by broth dilution method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Demonic axe-like conjugated alkynes in combating microbes. |
| AID1546641 | Antibacterial activity against Staphylococcus epidermidis assessed as diameter of zone of inhibition at 200 ug/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID278559 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium bifidum R0071 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID737329 | Antimicrobial activity against Pseudomonas aeruginosa MTCC 1688 at 500 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID637029 | Antibacterial activity against Acinetobacter johnsonii ATCC 17909 at 5 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID400007 | Antimicrobial activity against Staphylococcus aureus using distilled water as solvent by agar diffusion test | |||
| AID1091747 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as inhibition zones at 100 ug/disc at 37 degC for 24 hr | 2009 | Chemical & pharmaceutical bulletin, Jul, Volume: 57, Issue:7 | Synthesis, nematicidal and antimicrobial properties of Bis-[4-methoxy-3-[3-(4-fluorophenyl)-6-(4-methylphenyl)-2(aryl)-tetrahydro-2H-pyrazolo[3,4-d]thiazol-5-yl]phenyl]methanes. |
| AID1428253 | Antibacterial activity against Bacillus subtilis RCMB 000109 assessed as zone of inhibition at 30 ug/ml | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold. |
| AID644179 | Antibacterial activity against Escherichia coli ATCC 35210 treated for 24 hrs followed by sub-cultivated for 72 hrs by micro dilution method | 2012 | Bioorganic & medicinal chemistry, Feb-15, Volume: 20, Issue:4 | Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. |
| AID1193494 | Thermodynamic equilibrium solubility, log S of the compound in simulated gastric fluid at pH 1.2 at RT after 4 hrs by 96 well plate method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. |
| AID1435654 | Antimycobacterial activity against multidrug-resistant Mycobacterium tuberculosis 8666/2010 after 14 days by micromethod | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. |
| AID166720 | Tested for binding affinity against RNA construct E; n.b. means no observable binding | 2002 | Bioorganic & medicinal chemistry letters, Feb-11, Volume: 12, Issue:3 | Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers. |
| AID535774 | Antimicrobial activity against Mycobacterium ulcerans ATCC 19423 harboring pTY60H containing pCK0601 carrying the luxAB gene under the hsp60 promoter after 14 days determined according to RLU count by real-time luminescence method | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains. |
| AID1476364 | Antitubercular activity against streptomycin resistant Mycobacterium tuberculosis H37Rv ATCC 35820 after 24 hrs by MABA method | 2017 | Journal of medicinal chemistry, 10-26, Volume: 60, Issue:20 | Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity. |
| AID424578 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH338 (SCV-10) harboring Arg464Cys mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID544016 | Antimicrobial activity against Acinetobacter lwoffii isolate PGS47 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID1143264 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as growth inhibition after 2 to 3 weeks by turbidometry | 2014 | Journal of medicinal chemistry, Jun-12, Volume: 57, Issue:11 | Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. |
| AID689076 | Antibacterial activity against Escherichia coli assessed as zone of inhibition at 0.05 mg by agar diffusion method | 2012 | Journal of natural products, Sep-28, Volume: 75, Issue:9 | Sinularosides A and B, bioactive 9,11-secosteroidal glycosides from the South China Sea soft coral Sinularia humilis Ofwegen. |
| AID534826 | Antimicrobial activity against kanamycin-resistant Campylobacter fetus subsp. fetus CA74 harboring deletion in tet(44)::pCA64 resistant gene in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID336088 | Antimicrobial activity against Mycobacterium intracellular ATCC 23068 by twofold serial macrobroth dilution assay | 1993 | Journal of natural products, Nov, Volume: 56, Issue:11 | Antimicrobial compounds from Petalostemum purpureum. |
| AID1156685 | Antimicrobial activity against Staphylococcus aureus MTCC 96 assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID1233483 | Antimicrobial activity against Salmonella typhimurium MTCC 1251 assessed as inhibition of visual microbial growth incubated for 24 hrs at 37 degC | 2015 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 25, Issue:14 | Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. |
| AID601169 | Antibacterial activity against Bacillus subtilis using 1 x 10'4 CFU/ml inoculum after 24 hrs by microdilution method | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Microwave assisted synthesis and structure-activity relationship of 4-hydroxy-N'-[1-phenylethylidene]-2H/2-methyl-1,2-benzothiazine-3-carbohydrazide 1,1-dioxides as anti-microbial agents. |
| AID1105398 | Antibacterial activity against Pseudomonas aeruginosa MTCC 2581 assessed as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID1055955 | Antimycobacterial activity against cycloserine-resistant Mycobacterium tuberculosis ATCC 35826 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID94066 | Minimum inhibitory concentration against Klebsiella pneumoniae (ATCC 13883) | 2001 | Bioorganic & medicinal chemistry letters, Mar-26, Volume: 11, Issue:6 | Structure elucidation and conformational properties of a novel bioactive clerodane diterpene using a combination of high field NMR spectroscopy, computational analysis and X-ray diffraction. |
| AID279886 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 62.5 uM omeprazole | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID442423 | Antimicrobial activity against Listeria monocytogenes at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID494348 | Antibacterial activity against Escherichia coli by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8 | Synthesis, characterization and antimicrobial studies of 2-(4-methoxy-phenyl)-5-methyl-4-(2-arylsulfanyl-ethyl)-2,4-dihydro-[1,2,4] triazolo-3-ones and their corresponding sulfones. |
| AID1331257 | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 5 days by micro plate alamar blue assay | 2017 | Bioorganic & medicinal chemistry letters, 01-01, Volume: 27, Issue:1 | Synthesis, screening and docking analysis of hispolon analogs as potential antitubercular agents. |
| AID1428254 | Antibacterial activity against Pseudomonas aeruginosa RCMB 000103 assessed as zone of inhibition at 30 ug/ml | 2017 | European journal of medicinal chemistry, Jan-27, Volume: 126 | An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold. |
| AID1546647 | Antibacterial activity against Staphylococcus epidermidis assessed as reduction in microbial growth after 24 hrs by CLSI based microdilution method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID600672 | Antibacterial activity against Bacillus cereus clinical isolate after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID633851 | Antibacterial activity against Listeria monocytogenes NCTC 7973 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID572147 | Antimicrobial activity against AcrAB-deficient Escherichia coli AG100AX harboring pBADomeganorM plasmid containing Neisseria gonorrhoeae multidrug efflux pump NorM after 18 to 24 hrs by two fold dilution method | 2008 | Antimicrobial agents and chemotherapy, Sep, Volume: 52, Issue:9 | Functional cloning and characterization of the multidrug efflux pumps NorM from Neisseria gonorrhoeae and YdhE from Escherichia coli. |
| AID1333153 | Induction of membrane damage in CI/DOPG/DOPI large unilamellar vesicles assessed as calcein leakage at compound to lipid ratio of 1:2 to 1:8 by fluorescence based total phosphorous determination assay relative to control | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID1104317 | Antibacterial activity against Salmonella enterica subsp. enterica serovar Typhimurium ATCC 13311 at 48 degC measured after 24 hr by microdilution method | 2010 | Chemical & pharmaceutical bulletin, Feb, Volume: 58, Issue:2 | Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. |
| AID1456565 | Antifungal activity against Scopulariopsis sp. MTCC 3553 assessed as diameter of inhibition zone after 4 days by agar well diffusion method | |||
| AID603190 | Antibacterial activity against Staphylococcus aureus MTCC 96 by broth microdilution method | 2011 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 21, Issue:13 | Efficient synthesis, structural characterization and anti-microbial activity of chiral aryl boronate esters of 1,2-O-isopropylidene-α-D-xylofuranose. |
| AID608670 | Antibacterial activity against Clostridium perfringens assessed as zone of inhibition at 1000 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID374111 | Antimicrobial activity against azide-resistant aac(6')-Ib-cr deficient Escherichia coli J53 qnrA1 bearing pHS5 transconjugant from Enterobacter cloacae 641 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Nov, Volume: 51, Issue:11 | Prevalence and expression of the plasmid-mediated quinolone resistance determinant qnrA1. |
| AID562388 | Antimicrobial activity against vancomycin-susceptible Enterococcus faecalis clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID1055959 | Antimycobacterial activity against rifampin-resistant Mycobacterium tuberculosis ATCC 35838 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID382835 | Antibacterial activity against Staphylococcus aureus assessed as diameter of inhibition zone at 0.5% after 24 hrs | 2008 | European journal of medicinal chemistry, Feb, Volume: 43, Issue:2 | Structural and biological studies of mononuclear palladium(II) complexes containing N-substituted thiosemicarbazones. |
| AID678657 | Antibacterial activity against methicillin-resistant Staphylococcus aureus N 315 by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of novel N-acyl substituted quinolin-2(1H)-one derivatives as potential antimicrobial agents. |
| AID424584 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH367 (SCV-39) harboring Gly664Ser mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID293800 | Antibacterial activity against Bacillus subtilis | 2007 | European journal of medicinal chemistry, May, Volume: 42, Issue:5 | Synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives. |
| AID530288 | Antimicrobial activity against PR-39-resistant Salmonella enterica serovar Typhimurium LT2 DA6192 by Etest | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. |
| AID424597 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH339 (SCV-11) harboring -1 frameshift mutation at nucleotide 144 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID1105382 | Antibacterial activity against Xanthomonas oryzae ITCC B-47 assessed as as growth inhibition at 25 ug/disk after 24 hr by disk diffusion method | 2013 | European journal of medicinal chemistry, Jan, Volume: 59 | Microwave synthesis, characterization and bio-efficacy evaluation of novel chalcone based 6-carbethoxy-2-cyclohexen-1-one and 2H-indazol-3-ol derivatives. |
| AID424567 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH204 harboring deletion of nucleotide 203-231 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID381178 | Antibacterial activity against Pseudomonas aeruginosa after 24 to 72 hrs by disk diffusion method | 1999 | Journal of natural products, Sep, Volume: 62, Issue:9 | Antimicrobial and antitumor activities of mycosporulone. |
| AID636962 | Antibacterial activity against Bacillus subtilis ATCC 6633 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID456430 | Antibacterial activity against Pseudomonas aeruginosa NCIB 950 after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID600683 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs | 2011 | Bioorganic & medicinal chemistry, May-15, Volume: 19, Issue:10 | Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. |
| AID294554 | Antimicrobial activity against Candida albicans ATCC 90029 at 10 ug by disk diffusion method | 2007 | European journal of medicinal chemistry, Jun, Volume: 42, Issue:6 | Rapid synthesis of sulfone derivatives as potential anti-infectious agents. |
| AID278564 | Antimicrobial activity against 90 mins hydrogen peroxide-stressed Bifidobacterium longum ATCC 15708 after 18 hrs | 2007 | Antimicrobial agents and chemotherapy, Jan, Volume: 51, Issue:1 | Antibiotic susceptibility profile of bifidobacteria as affected by oxgall, acid, and hydrogen peroxide stress. |
| AID560222 | Antibacterial activity against Salmonella enterica serovar Typhimurium 01-4 by CLSI M7-A7 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Outer membrane protein STM3031 (Ail/OmpX-like protein) plays a key role in the ceftriaxone resistance of Salmonella enterica serovar Typhimurium. |
| AID603301 | Antitubercular activity against Mycobacterium tuberculosis H37Rv by Bactec 460 method | 2011 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 21, Issue:13 | 1-Chloro-2-formyl indenes and tetralenes as antitubercular agents. |
| AID534823 | Antimicrobial activity against nalidixic acid-resistant Campylobacter fetus subsp. fetus IMD523-06 bovine isolate harboring tet(44) and ant(6)-Ib resistance gene in presence of 5% lacked horse blood | 2010 | Antimicrobial agents and chemotherapy, Jul, Volume: 54, Issue:7 | Two novel antibiotic resistance genes, tet(44) and ant(6)-Ib, are located within a transferable pathogenicity island in Campylobacter fetus subsp. fetus. |
| AID283653 | Antibacterial activity against Escherichia coli K12 XL1 Blue in presence of 10 mM ascorbic acid | 2007 | Antimicrobial agents and chemotherapy, Mar, Volume: 51, Issue:3 | Effects of glutathione and ascorbic acid on streptomycin sensitivity of Escherichia coli. |
| AID732422 | Antimycobacterial activity Mycobacterium tuberculosis H37Rv assessed as growth inhibition measured at day 7 by broth microdilution method | 2013 | ACS medicinal chemistry letters, Jan-10, Volume: 4, Issue:1 | Synthesis and antiplasmodial and antimycobacterial evaluation of new nitroimidazole and nitroimidazooxazine derivatives. |
| AID534345 | Antimicrobial activity against Burkholderia pseudomallei Bp175 harboring mini-Tn7T-P1-bpeR+ after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID753881 | Antibacterial activity against Escherichia coli ATCC 10536 assessed as growth inhibition at 10 ug after 24 hrs by agar diffusion method | 2013 | European journal of medicinal chemistry, Jun, Volume: 64 | Synthesis, antibacterial activity and cytotoxicity of new fused pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-c][1,2,4]triazine derivatives from new 5-aminopyrazoles. |
| AID626289 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 0.25 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID326536 | Antimicrobial activity against Mycobacterium abscessus CH10 isolate after 3 to 5 days by broth microdilution method | 2007 | Antimicrobial agents and chemotherapy, May, Volume: 51, Issue:5 | In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. |
| AID206516 | Minimum inhibitory concentration against Staphylococcus hominis (ATCC 27844) | 2001 | Bioorganic & medicinal chemistry letters, Mar-26, Volume: 11, Issue:6 | Structure elucidation and conformational properties of a novel bioactive clerodane diterpene using a combination of high field NMR spectroscopy, computational analysis and X-ray diffraction. |
| AID279871 | Antimicrobial activity against Burkholderia pseudomallei KHW in presence of 7.8 uM prochlorperazine | 2007 | Antimicrobial agents and chemotherapy, Feb, Volume: 51, Issue:2 | Synergistic interaction between phenothiazines and antimicrobial agents against Burkholderia pseudomallei. |
| AID1055958 | Antimycobacterial activity against moxifloxacin-resistant Mycobacterium tuberculosis under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID633852 | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by microdilution method | 2011 | Bioorganic & medicinal chemistry, Dec-15, Volume: 19, Issue:24 | Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. |
| AID329351 | Antimicrobial activity against Yersinia pestis KIM6-2082.1+ in presence of iron rich PMH-D medium | 2008 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 18, Issue:8 | Small molecules with structural similarities to siderophores as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis. |
| AID456353 | Antibacterial activity against Bacillus subtilis NCIB 3610 after 24 hrs by agar well diffusion method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID1247087 | Antibacterial activity against Staphylococcus aureus after 24 hrs by two fold serial dilution method | 2015 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 25, Issue:19 | Synthesis of BF₃ catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. |
| AID716928 | Antibacterial activity against Escherichia coli ATCC 25922 at 1000 ug/mL after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core. |
| AID561109 | Antibacterial activity against Pasteurella multocida BB1043 harboring plasmid pB1000 bearing blaROB-1 gene and plasmid pB9956 bearing tetH gene by CLSI M31-A3 broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Multiresistance in Pasteurella multocida is mediated by coexistence of small plasmids. |
| AID1241203 | Inhibition of pre-miR-17 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID733699 | Antibacterial activity against Staphylococcus aureus MTCC 96 after 24 hrs | 2013 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 23, Issue:6 | Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. |
| AID442418 | Antimicrobial activity against Staphylococcus aureus at 1 umol/spot after 18 hrs by TLC-bioautographic method | 2010 | European journal of medicinal chemistry, Feb, Volume: 45, Issue:2 | Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents. |
| AID428870 | Antibacterial activity against Escherichia coli CSH-2 carrying Escherichia coli ARS3 pARS3 by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. |
| AID560223 | Antibacterial activity against Salmonella enterica serovar Typhimurium R200 expressing Outer membrane protein STM3031 by CLSI M7-A7 agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Aug, Volume: 53, Issue:8 | Outer membrane protein STM3031 (Ail/OmpX-like protein) plays a key role in the ceftriaxone resistance of Salmonella enterica serovar Typhimurium. |
| AID336089 | Antimicrobial activity against Escherichia coli ATCC 10536 by twofold serial macrobroth dilution assay | 1993 | Journal of natural products, Nov, Volume: 56, Issue:11 | Antimicrobial compounds from Petalostemum purpureum. |
| AID1241202 | Inhibition of pre-miR-373 (unknown origin) cleavage assessed as reduction of oncogenic microRNAs biogenesis at 200 uM by measuring fluorescence every minute for 5 hrs using 5'-FAM,3'-dabcyl-pre-miRNA beacons by FRET assay in presence of recombinant Dicer | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID636968 | Antibacterial activity against Staphylococcus aureus NRRL B 313 at 25 mg/ml after 24 hrs by agar diffusion test | 2012 | European journal of medicinal chemistry, Feb, Volume: 48 | Synthesis and in vitro antimycobacterial activity of compounds derived from (R)- and (S)-2-amino-1-butanol - The crucial role of the configuration. |
| AID424616 | Antibacterial activity against Enterococcus avium AIS2007004 isolated from patients rectum by broth microdilution method | 2008 | Antimicrobial agents and chemotherapy, Feb, Volume: 52, Issue:2 | Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan. |
| AID1201595 | Antibacterial activity against Bacillus subtilis ATCC 6633 assessed as growth inhibition after 24 hrs by turbidimetric analysis | 2015 | European journal of medicinal chemistry, May-05, Volume: 95 | Pentacyclic triterpene derivatives possessing polyhydroxyl ring A inhibit gram-positive bacteria growth by regulating metabolism and virulence genes expression. |
| AID1616518 | Antibacterial activity against Escherichia coli after 24 hrs by broth microdilution method | 2019 | Journal of natural products, 10-25, Volume: 82, Issue:10 | Highly Oxygenated Triterpenoids and Rare Tetraterpenoids from |
| AID294762 | Antibacterial activity against methicillin-resistant Staphylococcus aureus 873 after 2 weeks by broth dilution method | 2007 | Bioorganic & medicinal chemistry letters, May-01, Volume: 17, Issue:9 | Synthesis of new sugar derivatives from Stachys sieboldi Miq and antibacterial evaluation against Mycobacterium tuberculosis, Mycobacterium avium, and Staphylococcus aureus. |
| AID424345 | Antibacterial activity against fusidic acid-resistant Staphylococcus aureus AH188 harboring Gly664Ser mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID723720 | Antibacterial activity against Salmonella typhi after 24 hr by microdilution test | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID424828 | Antibacterial activity against kanamycin-resistant and fusidic acid-susceptible Staphylococcus aureus AH290 harboring duplication mutation at nucleotide 202-293 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID666779 | Antibacterial activity against Bacillus megaterium at 0.05 mg by agar diffusion test | 2012 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 22, Issue:13 | Bioactive briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. |
| AID285160 | Antimicrobial activity against non replicating persistence Mycobacterium tuberculosis H37Rv in aerobic condition assessed as bacterial density after 7 days | 2007 | Antimicrobial agents and chemotherapy, Apr, Volume: 51, Issue:4 | Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis. |
| AID1311821 | Antibacterial activity against rifampin/isoniazid-resistant Mycobacterium tuberculosis CSU 45 SRI 1377 by two fold serial dilution method | 2016 | Bioorganic & medicinal chemistry, 09-15, Volume: 24, Issue:18 | Antibacterial and anticancer activity of a series of novel peptides incorporating cyclic tetra-substituted C(α) amino acids. |
| AID456085 | Antibacterial activity against Proteus mirabilis after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID737332 | Antimicrobial activity against Klebsiella pneumoniae NCTC 13368 at 500 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID765555 | Antimicrobial activity against Mycobacterium smegmatis ATCC 607 after 48 to 72 hrs by double microdilution method | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities. |
| AID159919 | Minimum inhibitory concentration against P. aeruginosa; Not tested | 2001 | Bioorganic & medicinal chemistry letters, Mar-26, Volume: 11, Issue:6 | Structure elucidation and conformational properties of a novel bioactive clerodane diterpene using a combination of high field NMR spectroscopy, computational analysis and X-ray diffraction. |
| AID1596671 | Bactericidal activity against Micrococcus flavus ATCC 10240 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID537668 | Antibacterial activity against Mycobacterium smegmatis ATCC 607 after 18 hrs by agar-well diffusion method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities. |
| AID1191883 | Toxicity against macrophages (unknown origin) assessed cell viability at 4 times MIC level after 7 days by MTT assay | 2015 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 25, Issue:6 | A novel molecule with notable activity against multi-drug resistant tuberculosis. |
| AID509958 | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 24 hrs by BACTEC radiometric susceptibility assay | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | A bioactive labdane diterpenoid from Curcuma amada and its semisynthetic analogues as antitubercular agents. |
| AID358875 | Antimycobacterial activity against Mycobacterium tuberculosis ATCC 35818 at 25 ug/disk by disk diffusion susceptibility assay | 2001 | Journal of natural products, Mar, Volume: 64, Issue:3 | Pitipeptolides A and B, new cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. |
| AID1209457 | Unbound Cmax in human plasma | 2012 | Drug metabolism and disposition: the biological fate of chemicals, Jan, Volume: 40, Issue:1 | In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. |
| AID203052 | Antibacterial activity against gram negative bacteria Shigella flexenerii was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID1546640 | Antibacterial activity against Staphylococcus aureus MTCC 96 assessed as diameter of zone of inhibition at 200 ug/ml after 24 hrs by agar well diffusion method | 2020 | Journal of natural products, 01-24, Volume: 83, Issue:1 | Usnic Acid Enaminone-Coupled 1,2,3-Triazoles as Antibacterial and Antitubercular Agents. |
| AID376322 | Antibacterial activity against Micrococcus luteus isolate after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID414462 | Antitubercular activity against streptomycin-resistant Mycobacterium tuberculosis H37Rv ATCC 27294 after 7 days by microplate alamar blue assay | 2009 | Journal of medicinal chemistry, Apr-09, Volume: 52, Issue:7 | Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium tuberculosis. |
| AID737337 | Antimicrobial activity against Staphylococcus aureus ATCC 29513 at 1000 ug/ml after 24 hrs by cup plate method | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7 | Synthesis of novel 2-amino-4-(5'-substituted 2'-phenyl-1H-indol-3'-yl)-6-aryl-4H-pyran-3-carbonitrile derivatives as antimicrobial and antioxidant agents. |
| AID456435 | Antibacterial activity against Bacillus cereus NCIB 6349 after 72 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID1241212 | Binding affinity to 5'-FAM-pre-miR-372 (unknown origin) after 4 hrs by fluorescence assay in presence of 100-fold excess of Escherichia coli tRNA | 2015 | Bioorganic & medicinal chemistry, Sep-01, Volume: 23, Issue:17 | Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targeting. |
| AID723713 | Bactericidal activity against Salmonella typhi after 72 hrs by serial subcultivation method | 2013 | Bioorganic & medicinal chemistry, Jan-15, Volume: 21, Issue:2 | Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents. |
| AID719309 | Antimicrobial activity against Pseudomonas aeruginosa NCIM 5029 by broth dilution method | 2012 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 22, Issue:23 | Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues. |
| AID562812 | Antimicrobial activity against Escherichia coli DH5[alpha] | 2009 | Antimicrobial agents and chemotherapy, Oct, Volume: 53, Issue:10 | Complete nucleotide sequences of plasmids pEK204, pEK499, and pEK516, encoding CTX-M enzymes in three major Escherichia coli lineages from the United Kingdom, all belonging to the international O25:H4-ST131 clone. |
| AID540931 | Antimicrobial activity against paromomycin-resistant Streptomyces coelicolor SP1 harboring rpsL A262G and C271T mutant gene after 48 hrs | 2009 | Antimicrobial agents and chemotherapy, Mar, Volume: 53, Issue:3 | A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction. |
| AID424575 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH364 (SCV-36) harboring Asp434Asn mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID400009 | Antimicrobial activity against Pseudomonas aeruginosa using distilled water as solvent by agar diffusion test | |||
| AID1546159 | Antimicrobial activity against Bacillus subtilis assessed as zone of inhibition at 10 ug/ml | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID534343 | Antimicrobial activity against Burkholderia pseudomallei Bp173 harboring mini-Tn7T after 24 hrs by broth microdilution method | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | The BpeAB-OprB efflux pump of Burkholderia pseudomallei 1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides but is a broad-spectrum drug efflux system. |
| AID1454344 | Antibacterial activity Pseudomonas aeruginosa MTCC 1688 by agar well method | 2017 | Bioorganic & medicinal chemistry letters, 08-01, Volume: 27, Issue:15 | Synthesis and biological evaluation of 5-fatty-acylamido-1, 3, 4-thiadiazole-2-thioglycosides. |
| AID424573 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH366 (SCV-38) harboring Pro114His mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID424574 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH369 (SCV-41) harboring Gln115Leu mutation in fusA gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID289151 | Antimycobacterial activity against streptomycin, isoniazid, rifampicin, pyrazinamide-resistant Mycobacterium tuberculosis CIBIN 234 isolates | 2007 | Bioorganic & medicinal chemistry, Aug-15, Volume: 15, Issue:16 | Synthesis and antimycobacterial activity of 4-(5-substituted-1,3,4-oxadiazol-2-yl)pyridines. |
| AID442479 | Antibacterial activity against Staphylococcus epidermidis MTCC 435 by broth dilution method | 2010 | European journal of medicinal chemistry, Jan, Volume: 45, Issue:1 | Click chemistry: studies on the synthesis of novel fluorous tagged triazol-4-yl substituted quinazoline derivatives and their biological evaluation--theoretical and experimental validation. |
| AID1456566 | Antibacterial activity against Bacillus flexus MTCC 2909 after 24 hrs by broth microdilution method | |||
| AID207878 | Antibacterial activity against gram positive bacteria Staphylococcus epidermidis was determined by twofold Micro-broth dilution assay | 2004 | Bioorganic & medicinal chemistry letters, Feb-09, Volume: 14, Issue:3 | Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals. |
| AID401468 | Antimicrobial activity against Candida albicans ATCC 10231at 100 ug/mL by agar-dilution streak method | |||
| AID401459 | Antimicrobial activity against Staphylococcus aureus ATCC 13709 by agar-dilution streak method | |||
| AID539690 | Antifungal activity against Bacillus subtilis MTCC 441 by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Indium(III) chloride catalyzed three-component coupling reaction: a novel synthesis of 2-substituted aryl(indolyl)kojic acid derivatives as potent antifungal and antibacterial agents. |
| AID1324370 | Antibacterial activity against Bacillus subtilis after 24 hrs by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 26, Issue:22 | Novel substituted hydrazono indolo[2,1-b]quinazoline-6,12-dione analogues as cytostatic agents: Synthesis, crystal structure, biological evaluation and molecular docking studies. |
| AID1193495 | Thermodynamic equilibrium solubility, log S of the compound in simulated intestinal fluid at pH 6.8 at RT after 4 hrs by 96 well plate method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. |
| AID376321 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 48 hrs by serial dilution technique | 2006 | Journal of natural products, Apr, Volume: 69, Issue:4 | Linear sesquiterpene lactones from Anthemis auriculata and their antibacterial activity. |
| AID539695 | Antifungal activity against Klebsiella pneumoniae MTCC 618 by broth dilution method | 2010 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 20, Issue:24 | Indium(III) chloride catalyzed three-component coupling reaction: a novel synthesis of 2-substituted aryl(indolyl)kojic acid derivatives as potent antifungal and antibacterial agents. |
| AID1596679 | Bactericidal activity against Pseudomonas aeruginosa ATCC 27853 incubated for 24 hrs followed by re-plating on tryptic soy broth | 2019 | European journal of medicinal chemistry, Aug-01, Volume: 175 | Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies. |
| AID615481 | Antimicrobial activity against Bacillus subtilis at 25 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID1565883 | Antibacterial activity against Escherichia coli JM 109 assessed as growth inhibition measured after 24 hrs by two-fold broth dilution method | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | Design, synthesis and biological evaluation of novel diazaspiro[4.5]decan-1-one derivatives as potential chitin synthase inhibitors and antifungal agents. |
| AID1546089 | Antimicrobial activity against Staphylococcus aureus | 2019 | European journal of medicinal chemistry, Dec-15, Volume: 184 | Current scenario of tetrazole hybrids for antibacterial activity. |
| AID448315 | Antibacterial activity against Staphylococcus aureus MTCC 11 by broth dilution method | 2009 | European journal of medicinal chemistry, Nov, Volume: 44, Issue:11 | Synthesis, photochemical E (trans)-->Z (cis) isomerization and antimicrobial activity of 2-chloro-5-methylpyridine-3-olefin derivatives. |
| AID678658 | Antibacterial activity against Bacillus subtilis ATCC 6633 by disc diffusion method | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18 | Synthesis and biological evaluation of novel N-acyl substituted quinolin-2(1H)-one derivatives as potential antimicrobial agents. |
| AID400004 | Antimicrobial activity against Escherichia coli using pH 4.0 buffer as solvent by agar diffusion test | |||
| AID774295 | Antimycobacterial activity against kanamycin-resistant Mycobacterium tuberculosis ATCC 35827 | 2013 | Journal of natural products, Oct-25, Volume: 76, Issue:10 | Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis. |
| AID611682 | Antifungal activity against Microbotryum violaceum at 0.05 mg by agar diffusion method | 2011 | Journal of natural products, Jul-22, Volume: 74, Issue:7 | Bioactive 11,20-epoxy-3,5(16)-diene briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. |
| AID216526 | Minimal toxic dose that induced a reduction of 50% of cell growth in Vero cell line infected with Mycobacterium tuberculosis CIP 103471 | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12 | N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480. |
| AID694365 | Antibacterial activity against multidrug-resistant Mycobacterium tuberculosis MS-115 under anaerobic condition assessed as growth inhibition at 0.1 ug/ml by BACTEC method | 2012 | Bioorganic & medicinal chemistry, Nov-15, Volume: 20, Issue:22 | The synthesis and antituberculosis activity of 5'-nor carbocyclic uracil derivatives. |
| AID145144 | In vitro minimum inhibitory concentration against Mycobacterium tuberculosis CIP 103471 was determined | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12 | N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480. |
| AID532986 | Antibacterial activity against Pseudomonas aeruginosa NCIM 5029 | 2010 | Antimicrobial agents and chemotherapy, Aug, Volume: 54, Issue:8 | N-acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. |
| AID1286941 | Antibacterial activity against Staphylococcus aureus MTCC 96 by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 26, Issue:6 | Indole-2-carboxylic acid derived mono and bis 1,4-disubstituted 1,2,3-triazoles: Synthesis, characterization and evaluation of anticancer, antibacterial, and DNA-cleavage activities. |
| AID1179272 | Antimicrobial activity against Salmonella paratyphi B at 1 mg/disc after 24 hrs by disc diffusion assay | 2014 | Bioorganic & medicinal chemistry letters, Jul-15, Volume: 24, Issue:14 | Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. |
| AID747761 | Antibacterial activity against Bacillus subtilis | 2013 | Bioorganic & medicinal chemistry letters, Jun-01, Volume: 23, Issue:11 | Synthesis, spectral and antimicrobial evaluation of some novel 1-methyl-3-alkyl-2,6-diphenylpiperidin-4-one oxime carbonates. |
| AID626282 | Antibacterial activity against Escherichia coli ATCC 25922 at 1 mg/mL after 24 hrs by by agar-well diffusion method | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11 | Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents. |
| AID1156686 | Antimicrobial activity against methicillin-resistant Staphylococcus aureus assessed as absence of visible growth after 48 to 72 hrs | 2014 | European journal of medicinal chemistry, Aug-18, Volume: 83 | Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and molecular docking studies. |
| AID1055966 | Antimycobacterial activity against Mycobacterium tuberculosis clinical isolate X001354 under normoxic condition after 7 days by MABA assay | 2013 | Journal of natural products, Nov-22, Volume: 76, Issue:11 | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. |
| AID456079 | Antibacterial activity against Staphylococcus aureus ATCC 6538 after 72 hrs by serial sub-cultivation method | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. |
| AID1235639 | Antibacterial activity against Staphylococcus aureus DSM 799 incubated for 24 hrs by disk diffusion method | 2015 | Journal of natural products, Aug-28, Volume: 78, Issue:8 | Endophytic Diaporthe sp. LG23 Produces a Potent Antibacterial Tetracyclic Triterpenoid. |
| AID355889 | Antimicrobial activity against Staphylococcus aureus ATCC 6538 after 36 hrs under aerobic condition by microdilution method | 2003 | Journal of natural products, May, Volume: 66, Issue:5 | Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity. |
| AID456436 | Antibacterial activity against Staphylococcus aureus NCIB 8588 after 72 hrs | 2010 | Bioorganic & medicinal chemistry, Jan-01, Volume: 18, Issue:1 | Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives. |
| AID585429 | Antimicrobial activity against Escherichia coli C600 ST2-T transconjugant harboring oqxAB, qnrB6 and aac(6')-Ib-cr genes by CLSI agar dilution method | 2010 | Antimicrobial agents and chemotherapy, Oct, Volume: 54, Issue:10 | Prevalence and dissemination of oqxAB in Escherichia coli isolates from animals, farmworkers, and the environment. |
| AID515229 | Antibacterial activity against Staphylococcus epidermidis at 50 ug/ml after 18 hrs by cup plate method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10 | Anti-tubercular agents. Part 5: synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners. |
| AID530251 | Antimicrobial activity against yigB deficient Escherichia coli K-12 BW-25113 assessed as decrease in persistence at 10 ug/ml after 3 hrs by time kill analysis relative to wild type | 2008 | Antimicrobial agents and chemotherapy, Aug, Volume: 52, Issue:8 | Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. |
| AID1174109 | Antimycobacterial activity against isoniazid, rifampin, ethambutol, streptomycin-resistant Mycobacterium tuberculosis after 7 days by microplate Alamar blue assay | 2015 | European journal of medicinal chemistry, Jan-07, Volume: 89 | Antimycobacterial activity of natural products and synthetic agents: pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis. |
| AID608663 | Antibacterial activity against Escherichia coli ATCC 25922 assessed as zone of inhibition at 500 ug/ml after 24 hrs by agar diffusion method | 2011 | European journal of medicinal chemistry, Aug, Volume: 46, Issue:8 | Synthesis, characterization and antimicrobial studies of some new pyrazole incorporated imidazole derivatives. |
| AID404896 | Antibacterial activity against high-level gentamicin resistant Streptococcus pasteurianus SB28 isolate carrying transposon-borne resistance gene [aac(6')Ie-aph(2'')Ia] by agar dilution method | 2007 | Antimicrobial agents and chemotherapy, Jul, Volume: 51, Issue:7 | High-level gentamicin resistance mediated by a Tn4001-like transposon in seven nonclonal hospital isolates of Streptococcus pasteurianus. |
| AID1193492 | Thermodynamic equilibrium solubility, log S of the compound in water at RT after 4 hrs by 96 well plate method | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. |
| AID595279 | Antimicrobial activity against Staphylococcus aureus ATCC 25930 after 24 hrs by two fold serial dilution method | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Synthesis, spectral, crystal structure and in vitro antimicrobial evaluation of imidazole/benzotriazole substituted piperidin-4-one derivatives. |
| AID716927 | Antibacterial activity against Escherichia coli ATCC 25922 at 500 ug/mL after 24 hrs by well plate method | 2012 | Bioorganic & medicinal chemistry letters, Dec-15, Volume: 22, Issue:24 | Synthesis, antioxidant and antimicrobial activity of novel vanillin derived piperidin-4-one oxime esters: preponderant role of the phenyl ester substituents on the piperidin-4-one oxime core. |
| AID1143270 | Antimycobacterial activity against ofloxacin-resistant Mycobacterium tuberculosis 12119 assessed as growth inhibition after 2 to 3 weeks by turbidometry | 2014 | Journal of medicinal chemistry, Jun-12, Volume: 57, Issue:11 | Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity. |
| AID1253867 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis FJ05195 after 3 to 4 weeks by microplate alamar blue assay | 2015 | Bioorganic & medicinal chemistry letters, Nov-15, Volume: 25, Issue:22 | Discovery of the disubstituted oxazole analogues as a novel class anti-tuberculotic agents against MDR- and XDR-MTB. |
| AID1286943 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth dilution method | 2016 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 26, Issue:6 | Indole-2-carboxylic acid derived mono and bis 1,4-disubstituted 1,2,3-triazoles: Synthesis, characterization and evaluation of anticancer, antibacterial, and DNA-cleavage activities. |
| AID509467 | Antibacterial activity against Escherichia coli at 50 ug/mL | 2010 | European journal of medicinal chemistry, Sep, Volume: 45, Issue:9 | Conventional and microwave assisted synthesis of some new N-[(4-oxo-2-substituted aryl -1, 3-thiazolidine)-acetamidyl]-5-nitroindazoles and its antimicrobial activity. |
| AID774840 | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 0.5 to 1 mg/ml at 37 degC after 18 hrs by well plate method | 2013 | European journal of medicinal chemistry, Oct, Volume: 68 | Synthesis, characterization and molecular docking studies of some new 1,3,4-oxadiazolines bearing 6-methylpyridine moiety for antimicrobial property. |
| AID601599 | Antibacterial activity against Escherichia coli DH5[alpha] at 10 ug/disk after 24 hrs by disc diffusion assay | 2011 | European journal of medicinal chemistry, Jun, Volume: 46, Issue:6 | Synthesis of 2-aziridinyl phosphonates by modified Gabriel-Cromwell reaction and their antibacterial activities. |
| AID464054 | Antibacterial activity against Salmonella enteritidis ATCC 13076 after 48 hrs by serial dilution technique | 2010 | Journal of natural products, Feb-26, Volume: 73, Issue:2 | Sesquiterpene lactones from Anthemis melanolepis and their antibacterial and cytotoxic activities. Prediction of their pharmacokinetic profile. |
| AID574807 | Antimycobacterial activity against extensively drug-resistant Mycobacterium tuberculosis isolate 761 horboring rpoB S531L/Q510P, katG S315T/R463L, gyrA D94N/S95T, rrs G1484T by CLSI method | 2010 | Antimicrobial agents and chemotherapy, Nov, Volume: 54, Issue:11 | Emergence and molecular characterization of extensively drug-resistant Mycobacterium tuberculosis clinical isolates from the Delhi Region in India. |
| AID424592 | Antibacterial activity against kanamycin-resistant Staphylococcus aureus AH392 (SCV-64) harboring -1 frameshift mutation at nucleotide 383 in rplF gene after 18 to 24 hrs by Etest strip assay | 2007 | Antimicrobial agents and chemotherapy, Dec, Volume: 51, Issue:12 | Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. |
| AID615570 | Antimicrobial activity against Staphylococcus aureus at 50 ug/ml by agar plate diffusion technique | 2011 | European journal of medicinal chemistry, May, Volume: 46, Issue:5 | Novel dihydropyrimidines and its pyrazole derivatives: synthesis and pharmacological screening. |
| AID1079945 | Animal toxicity known. [column 'TOXIC' in source] | |||
| AID625290 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver fatty | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID648388 | Antibacterial activity against Proteus vulgaris MTCC 1771 at 10 ug/disc after 24 hrs by disc diffusion assay | 2012 | European journal of medicinal chemistry, May, Volume: 51 | Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. |
| AID562380 | Antimicrobial activity against Enterococcus faecium expressing VanB gene clinical isolates assessed as percent susceptible isolates by broth microdilution method | 2009 | Antimicrobial agents and chemotherapy, Nov, Volume: 53, Issue:11 | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. |
| AID625376 | Antibacterial activity against Klebsiella pneumoniae ATCC 15490 after 24 hrs by twofold serial dilution method | 2011 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 21, Issue:21 | Synthesis, stereochemistry and in vitro antimicrobial evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-4-phenyl-2,3-dihydrothiazoles. |
| AID544004 | Antimicrobial activity against Aerococcus viridans isolate PGS22 harboring sul1 to sul3 genes assessed as antibiotic resistance breakpoint by agar dilution method | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. |
| AID541856 | Antimicrobial activity against florfenicol-resistant Edwardsiella ictaluri M07-1 by microdilution assay | 2009 | Antimicrobial agents and chemotherapy, Feb, Volume: 53, Issue:2 | IncA/C plasmid-mediated florfenicol resistance in the catfish pathogen Edwardsiella ictaluri. |
| AID1456563 | Antibacterial activity against Pseudomonas aeruginosa MTCC 4727 assessed as diameter of inhibition zone measured after 20 hrs by agar well diffusion method | |||
| AID540177 | Antibacterial activity against Bacillus subtilis NCIM 2439 after 24 hrs by twofold serial dilution method | 2010 | European journal of medicinal chemistry, Nov, Volume: 45, Issue:11 | Synthesis and anti-tubercular and antimicrobial activities of some 2r,4c-diaryl-3-azabicyclo[3.3.1]nonan-9-one N-isonicotinoylhydrazone derivatives. |
| AID1311819 | Antibacterial activity against Mycobacterium tuberculosis H37Ra ATCC 2517 by two fold serial dilution method | 2016 | Bioorganic & medicinal chemistry, 09-15, Volume: 24, Issue:18 | Antibacterial and anticancer activity of a series of novel peptides incorporating cyclic tetra-substituted C(α) amino acids. |
| AID1333266 | Antimycobacterial activity against Mycobacterium smegmatis MC2 155 assessed as inhibition of respiratory ATP synthesis by measuring ATP level at 4 times MIC measured after 1 hr by luciferase reporter gene assay (Rvb = 90.6%) | 2016 | European journal of medicinal chemistry, Nov-10, Volume: 123 | Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. |
| AID1555428 | Antibacterial activity against Klebsiella pneumoniae assessed as diameter of zone of inhibition at 10 ug/disc by disc diffusion method | 2019 | European journal of medicinal chemistry, Aug-15, Volume: 176 | Phytochemical and pharmacological attributes of piperine: A bioactive ingredient of black pepper. |
| AID625289 | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for liver disease | 2011 | PLoS computational biology, Dec, Volume: 7, Issue:12 | Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). |
| AID245295 | In vitro minimum inhibitory concentration of compound against Methicillin-resistant Staphylococcus aureus ATCC 29213 | 2005 | Bioorganic & medicinal chemistry letters, Jan-17, Volume: 15, Issue:2 | Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones. |
| AID504749 | qHTS profiling for inhibitors of Plasmodium falciparum proliferation | 2011 | Science (New York, N.Y.), Aug-05, Volume: 333, Issue:6043 | Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 16813 (83.97) | 18.7374 |
| 1990's | 1006 (5.02) | 18.2507 |
| 2000's | 911 (4.55) | 29.6817 |
| 2010's | 1058 (5.28) | 24.3611 |
| 2020's | 234 (1.17) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.
| This Compound (88.40) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 362 (1.63%) | 5.53% |
| Reviews | 496 (2.23%) | 6.00% |
| Case Studies | 672 (3.02%) | 4.05% |
| Observational | 3 (0.01%) | 0.25% |
| Other | 20,694 (93.10%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Randomized Study to Compare Clinical Outcomes in Patients With Osteomyelitis Treated With Intravenous Antibiotics Versus Intravenous Antibiotics With an Early Switch to Oral Antibiotics [NCT02099240] | Early Phase 1 | 11 participants (Actual) | Interventional | 2014-03-06 | Terminated(stopped due to Not enough patient enrollment and lack of staffing) | ||
| Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis [NCT03625739] | 800 participants (Anticipated) | Observational [Patient Registry] | 2018-07-01 | Recruiting | |||
| A Open-label, Single Sequence Clinical Trial to Investigate the Pharmacokinetic Characteristics of Second-Line Anti-Tuberculosis Agents After Multiple Oral/Intramuscular Administration in Healthy Male Volunteers [NCT02128308] | Phase 1 | 16 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| [NCT02604849] | 44 participants (Actual) | Observational | 2012-07-31 | Completed | |||
| Preoperative Mechanical Bowel Preparation With Oral Antibiotics Reduces Surgical Site Infection After Elective Colorectal Surgery for Malignancies: a Propensity Matching Analysis [NCT04258098] | 806 participants (Actual) | Observational | 2011-01-01 | Completed | |||
| Safety and Efficacy of Gentamicin Versus Streptomycin for the Treatment of Naturally Occurring Human Plague and Evaluation of Rapid Diagnostic Test Kits for Yersinia Pestis [NCT00128466] | Phase 2/Phase 3 | 114 participants (Actual) | Interventional | 2004-08-31 | Completed | ||
| Randomized Controlled Trial Comparing Efficacy of 8 Weeks Treatment With Clarithromycin and Rifampicin Versus Streptomycin and Rifampicin for Buruli Ulcer (M. Ulcerans Infection) [NCT01659437] | Phase 2/Phase 3 | 310 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in [NCT00000796] | 525 participants | Interventional | Completed | ||||
| [NCT00004444] | 24 participants | Interventional | 1994-11-30 | Completed | |||
| [NCT00004689] | Phase 2 | 50 participants | Interventional | 1991-01-31 | Completed | ||
| New Super-short Course Regimen for Retreatment Pulmonary Tuberculosis [NCT02331823] | Phase 4 | 864 participants (Anticipated) | Interventional | 2013-06-30 | Recruiting | ||
| An Open-label, Randomised, Non-inferiority Trial of the Efficacy and Safety of Ciprofloxacin Versus an Aminoglycoside Followed by Ciprofloxacin in the Treatment of Bubonic Plague [NCT04110340] | Phase 3 | 600 participants (Anticipated) | Interventional | 2020-02-15 | Recruiting | ||
| A Phase I/II, Randomized, Blinded and Placebo-controlled Trial to Evaluate the Safety and Potential Efficacy of Allogeneic Human Mesenchymal Stem Cell Infusion in Patients With Aging Frailty [NCT02065245] | Phase 1/Phase 2 | 65 participants (Actual) | Interventional | 2014-03-03 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||