Page last updated: 2024-08-07 18:47:14
Histamine H4 receptor
An H4 histamine receptor that is encoded in the genome of mouse. [OMA:Q91ZY2, PRO:DNx]
Synonyms
H4R;
HH4R
Research
Bioassay Publications (10)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
Compounds (8)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| histamine | Mus musculus (house mouse) | Ki | 0.0607 | 2 | 2 |
| clobenpropit | Mus musculus (house mouse) | Ki | 0.1408 | 2 | 2 |
| histamine dihydrochloride | Mus musculus (house mouse) | Ki | 1.3196 | 2 | 2 |
| thioperamide | Mus musculus (house mouse) | Ki | 0.0728 | 2 | 2 |
| jnj 7777120 | Mus musculus (house mouse) | IC50 | 0.0400 | 1 | 1 |
| jnj 7777120 | Mus musculus (house mouse) | Ki | 2.6645 | 4 | 12 |
| pf-3893787 | Mus musculus (house mouse) | Ki | 0.0322 | 3 | 3 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| histamine | Mus musculus (house mouse) | EC50 | 2.8596 | 5 | 5 |
| histamine | Mus musculus (house mouse) | Kd | 0.0420 | 1 | 1 |
| clobenpropit | Mus musculus (house mouse) | EC50 | 0.8511 | 1 | 1 |
| histamine dihydrochloride | Mus musculus (house mouse) | EC50 | 1.2157 | 2 | 2 |
| 4-methylhistamine | Mus musculus (house mouse) | EC50 | 1.5849 | 1 | 1 |
| thioperamide | Mus musculus (house mouse) | EC50 | 0.1651 | 2 | 2 |
| vuf 8430 | Mus musculus (house mouse) | EC50 | 8.7096 | 1 | 1 |
| jnj 7777120 | Mus musculus (house mouse) | EC50 | 0.3984 | 2 | 2 |