Page last updated: 2024-11-05

toluidine red

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Toluidine Red is a red azo dye that was historically used in the textile industry. It is synthesized through a diazotization reaction of p-toluidine with a coupling agent, typically a naphthol derivative. Toluidine Red was known for its bright red color and its ability to dye various fabrics. However, it has been largely replaced by newer dyes due to its potential toxicity and environmental concerns associated with azo dyes. The study of Toluidine Red, along with other azo dyes, helps in understanding the chemistry of dye synthesis, color generation, and the environmental impact of these compounds.'

Cross-References

ID SourceID
PubMed CID17047
CHEMBL ID2138372
CHEBI ID82428
SCHEMBL ID57955
SCHEMBL ID340782
SCHEMBL ID13475196
SCHEMBL ID4223162
MeSH IDM0113033

Synonyms (204)

Synonym
1-[(4-methyl-2-nitrophenyl)diazenyl]naphthalen-2-ol
isol toluidine red rng
symuler fast scarlet 4r
toluidine toner hr x-2700
chromatex red j
segnale light red br
isol toluidine red hb
carnelio helio red
helio fast red bn
toluidine red light
toluidine red rt-115
helio fast red rl
toluidine toner keep hr x-2742
deep fastona red
helio red rl
monolite fast scarlet rna
silosol red rbn
irgalite red rnpx
oralith red p4r
c.p.toluidine toner light rs-3140
toluidine red d 28-3930
recolite fast red rl
dainichi permanent red 4 r
isol toluidine red rnb
monolite fast scarlet rt
toluidine red
toluidine red r
accosperse toluidine red xl
siegle red 1
hansa red g
toluidine red 3b
nsc-45193
siegle red b
fast red r
enialit light red rl
lake red 4rii
fast red j
lake red 4r
adc toluidine red b
toluidine red toner
monolite fast scarlet ca
2-naphthalenol, 1-[(4-methyl-2-nitrophenyl)azo]-
hansa scarlet rn
lithol fast scarlet rn
segnale light red 2b
toluidine toner dark 5040
graphtol red a-4rl
isol fast red rn2b
[(4-methyl-2-nitrophenyl)azo]-2-naphthol
kromon helio fast red
lutetia fast red 3r
nsc45193
helio fast red rn
c.p.toluidine toner deep x-1865
fast red a
isol fast red rnb
segnale light red b
toluidine red bfb
c.p.toluidine toner rt-6101
isol fast red rng
monolite fast scarlet gsa
irgalite red pv2
no. 2 forthfast scarlet
segnale light red rl
fast red ab
toluidine toner l20-3300
siloton red rll
c.i. 12120
sanyo scarlet pure no. 1000
siegle red bb
fastona scarlet ys
eljon fast scarlet pv extra
vulcafor scarlet a
1-(o-nitro-p-tolylazo)-2-naphthol
isol fast red hb
toluidine toner hr x-2741
monolite fast scarlet rnv
permanent red 4r
c.p.toluidine toner rt-6104
toluidine toner
recolite fast red rbl
kromon helio fast red ys
fastona scarlet rl
basoflex red 361
helio red toner
syton fast scarlet rd
hansa red b
c.p.toluidine toner a-2989
hansa scarlet rnc
2425-85-6
lutetia fast scarlet rjn
monolite fast scarlet rb
toluidine red 4r
sanyo scarlet pure
recolite fast red ryl
eljon fast scarlet rn
isol fast red rn2g
d and c red no. 35
toluidine red bfgg
hispalit fast scarlet rn
toluidine toner rt-252
monolite fast scarlet rn
isol toluidine red rn2g
silogomma red rll
versal scarlet rnl
calcotone toluidine red yp
duplex toluidine red l 20-3140
silosol red rn
monolite fast scarlet rba
c.p.toluidine toner dark rs-3340
fast red je
fastona red b
toluidine red m 20-3785
c.p.toluidine toner a-2990
toluidine red xl 20-3050
irgalite scarlet rb
versal scarlet prnl
hansa scarlet rb
segnale light red c4r
syton fast scarlet rn
syton fast scarlet rb
lutetia fast scarlet rf
independence red
toluidine red 10451
isol toluidine red rn2b
irgalite fast scarlet rnd
siloton red brll
irgalite fast red p4r
1-(4-methyl-2-nitrophenylazo)-2-naphthol
1-[(e)-(4-methyl-2-nitrophenyl)diazenyl]-2-naphthol
c.p. toluidine toner dark rs-3340
hsdb 4357
nsc 45193
c.p. toluidine toner light rs-3140
ccris 4013
ai3-30760
toluidine toner l 20-3300
c.p. toluidine toner a-2989
einecs 219-372-2
c.i.12120
c.p. toluidine toner a-2990
1-((4-methyl-2-nitrophenyl)azo)-2-naphthalenol
c.p. toluidine toner rt-6104
2-naphthalenol, 1-((4-methyl-2-nitrophenyl)azo)-
cp toluidine toner a-2989
fast red a (van)
c.p. toluidine toner deep x-1865
1-((2-nitro-4-methylphenyl)azo)-2-naphthol
nci-c60366
ci 12120
((4-methyl-2-nitrophenyl)azo)-2-naphthol
c.p. toluidine toner rt-6101
recolite fast red bl
toluidine red, dye content 70 %
NCGC00164084-01
C19373
7k26s08256 ,
ec 219-372-2
unii-7k26s08256
2-naphthalenol, 1-(2-(4-methyl-2-nitrophenyl)diazenyl)-
AKOS024319605
(1z)-1-[(4-methyl-2-nitro-phenyl)hydrazinylidene]naphthalen-2-one
(1z)-1-[(4-methyl-2-nitrophenyl)hydrazinylidene]-2-naphthalenone
A817175
AKOS016009930
FT-0634264
aka221 [inci]
ci 12120 [inci]
SCHEMBL57955
SCHEMBL340782
SCHEMBL13475196
CHEBI:82428 ,
1-((4-methyl-2-nitrophenyl)diazenyl)naphthalen-2-ol
1-(2-nitro-4-methylphenylazo)-2-naphthol
SCHEMBL4223162
CHEMBL2138372
toluidine toner 4r x-2700
2-nitro-p-toluidine-2-naphthol
isol fast red rn 2b
isol fast red rn 2g
isol toluidine red rn 2g
toluidine red b
irgalite red pv 2
isol toluidine red rn 2b
2-naphthalenol, 1-[2-(4-methyl-2-nitrophenyl)diazenyl]-
1-[(2-nitro-4-methylphenyl)azo]-2-naphthol
irgalite fast red p 4r
ZLFVRXUOSPRRKQ-UHFFFAOYSA-N
1-[(4-methyl-2-nitrophenyl)diazenyl]-2-naphthol #
segnale light red c 4r
DTXSID8021226
AKOS028109424
toluidine red, analytical standard
1-[(z)-(4-methyl-2-nitrophenyl)diazenyl]-2-naphthol
J-015420
(e)-1-((4-methyl-2-nitrophenyl)diazenyl)naphthalen-2-ol
(1z)-1-[(4-methyl-2-nitrophenyl)hydrazinylidene] naphthalen-2-one
Q27155932
toluidine red 100 microg/ml in acetone
E79251
BS-52951
1-(4-methyl-2-nitro-phenyl)diazenylnaphthalen-2-ol
DTXSID10859728
1-[(e)-(4-methyl-2-nitrophenyl)diazenyl]naphthalen-2-ol
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
pregnane X nuclear receptorHomo sapiens (human)Potency44.66840.005428.02631,258.9301AID720659
aryl hydrocarbon receptorHomo sapiens (human)Potency17.78280.000723.06741,258.9301AID651777
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency39.40960.000627.21521,122.0200AID651741; AID720636
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.84

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.84 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.78 (4.65)
Search Engine Demand Index64.68 (26.88)
Search Engine Supply Index4.00 (0.95)

This Compound (29.84)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (25.00%)6.00%
Case Studies1 (12.50%)4.05%
Observational0 (0.00%)0.25%
Other5 (62.50%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]