aminolevulinic acid has been researched along with Sensitivity and Specificity in 211 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To confirm the reproducibility of the effectiveness and safety in photodynamic diagnosis of non-muscle-invasive bladder cancer using 5-aminolevulinic acid in a prospective multicenter non-randomized phase III trial." | 9.27 | Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study. ( Fujimoto, K; Furuse, H; Inoue, K; Matsuyama, H; Miyake, M; Nagao, K; Nakai, Y; Oyama, M; Ozono, S; Shimamoto, T; Shuin, T; Tsuzuki, T, 2018) |
| "Photodynamic diagnosis (PDD) of non-muscle-invasive bladder cancer (NMIBC) following transurethral administration of a hexalated form of 5-aminolevulinic acid (5-ALA), 5-ALA hexyl ester, is widely performed in Western countries." | 9.20 | Oral 5-aminolevulinic acid mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A randomized, double-blind, multicentre phase II/III study. ( Anai, S; Fujimoto, K; Fukuhara, H; Furuse, H; Hara, T; Hirao, Y; Inoue, K; Kai, F; Matsuyama, H; Narukawa, M; Oyama, M; Ozono, S; Shuin, T; Ueno, M, 2015) |
| "We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence." | 9.09 | Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy. ( Baumgartner, R; Hofstetter, A; Knuechel, R; Kriegmair, M; Stepp, H; Zaak, D, 1999) |
| "5-Aminolevulinic acid facilitates detection of neoplastic disease during transurethral resection of bladder cancer and increases the accuracy of diagnosis." | 9.09 | Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy. ( Baumgartner, R; Hofstetter, A; Knuechel, R; Kriegmair, M; Stepp, H; Zaak, D, 1999) |
| "1) To determine whether fluorescence cystoscopy after intravesical administration of 5-aminolevulinic acid (5-ALA) is more sensitive in detection of dysplasia and bladder cancer when compared with conventional cystoscopy." | 9.09 | Cystoscopic diagnosis of bladder cancer by intravesical instillation of 5-aminolevulinic acid induced porphyrin fluorescence--the Singapore experience. ( Cheng, CW; Lau, WK; Olivo, M; Tan, PH, 2000) |
| "We performed a systematic review and meta-analysis to address the (added) value of intraoperative 5-aminolevulinic acid (5-ALA)-guided resection of high-grade malignant gliomas compared with conventional neuronavigation-guided resection, with respect to diagnostic accuracy, extent of tumor resection, safety, and survival." | 8.89 | Intraoperative fluorescence-guided resection of high-grade malignant gliomas using 5-aminolevulinic acid-induced porphyrins: a systematic review and meta-analysis of prospective studies. ( Chen, X; Dong, X; Han, D; Li, H; Liu, H; Liu, Y; Shen, C; Shi, C; Teng, L; Wang, C; Wang, L; Wu, J; Yang, G; Zhao, S, 2013) |
| "To compare fluorescence intensity of tumor specimens, as measured by a fluorescence-guided surgery microscope and a spectrometer, to evaluate tumor infiltration of dura mater around meningiomas with help of these 2 different 5-aminolevulinic acid (5-ALA)-based fluorescence tools, and to correlate fluorescence intensity with histopathologic data." | 7.85 | Fluorescence Behavior and Dural Infiltration of Meningioma Analyzed by 5-Aminolevulinic Acid-Based Fluorescence: Operating Microscope Versus Mini-Spectrometer. ( Beseoglu, K; Cornelius, JF; Felsberg, J; Fischer, I; Kamp, M; Knipps, J; Neumann, LM; Steiger, HJ, 2017) |
| "We evaluated the feasibility of photodynamic diagnosis of bladder cancer by spectrophotometric analysis of voided urine samples after extracorporeal treatment with 5-aminolevulinic acid (ALA)." | 7.81 | Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Masaomi, K; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2015) |
| "We demonstrated that protoporphyrin IX levels in urinary cells treated with ALA could be quantitatively detected by spectrophotometer in patients with bladder cancer." | 7.81 | Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Masaomi, K; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2015) |
| "To evaluate the use of 5-aminolevulinic acid (5-ALA) for the noninvasive detection of malignant gliomas by using in vivo magnetic resonance (MR) imaging in a mouse brain tumor model." | 7.80 | Malignant glioma: MR imaging by using 5-aminolevulinic acid in an animal model. ( Bishop, D; Cho, HR; Choi, SH; Doble, P; Han, MH; Hare, D; Kim, D; Kim, DH; Moon, WK; Park, CK, 2014) |
| "This study was undertaken to evaluate the clinical value of photodynamic diagnosis (PDD) with intravesical and oral instillation of 5-aminolevulinic acid (ALA) (ALA-PDD), and transurethral resection of bladder tumor (TURBT) guided by ALA-PDD (PDD-TURBT) for nonmuscle invasive bladder cancer." | 7.78 | Comparison between intravesical and oral administration of 5-aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer. ( Fukuhara, H; Furihata, M; Iiyama, T; Inoue, K; Kamada, M; Kurabayashi, A; Miyamura, M; Shimamoto, T; Shuin, T; Tanimura, M; Watanabe, H, 2012) |
| " The goal of this study is to investigate the usefulness of 5-aminolevulinic acid (ALA)-assisted in situ fluorescence diagnosis of subclinical lesion and latent HPV infection." | 7.74 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "5-Aminolevulinic acid induced fluorescence endoscopy has outstanding sensitivity for detecting early stage bladder cancer." | 7.71 | Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. ( Baumgartner, R; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Schneede, P; Siebels, M; Stepp, H; Wagner, S; Zaak, D, 2001) |
| "In 25 cases (53 biopsies) of a history of or suspicion for bladder cancer 5-aminolevulinic acid induced fluorescence endoscopy and fluorescence image quantification were performed." | 7.71 | Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. ( Baumgartner, R; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Schneede, P; Siebels, M; Stepp, H; Wagner, S; Zaak, D, 2001) |
| "Our observations suggest that 5-aminolevulinic acid-induced porphyrin fluorescence may label malignant gliomas safely and accurately enough to enhance the completeness of tumor removal." | 7.70 | Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence. ( Fritsch, C; Goetz, AE; Goetz, C; Kiefmann, R; Reulen, HJ; Stepp, H; Stocker, S; Stummer, W; Wagner, S, 1998) |
| "To determine the accuracy of the indicators for detecting lead poisoning." | 7.70 | [Re-assessment of indicators for screening lead poisoning]. ( Lin, G; Lü, L; Wang, Q; Xu, M; Zou, H, 1999) |
| "We determined whether the sensitivity of detecting dysplasia or early bladder cancer can be improved by 5-aminolevulinic acid induced porphyrin fluorescence." | 7.69 | Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. ( Baumgartner, R; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Stepp, H, 1996) |
| "5-Aminolevulinic acid (20 mg/kg) was orally administered 3 h before transurethral resection of bladder tumors using white light or fluorescent light." | 6.87 | Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study. ( Fujimoto, K; Furuse, H; Inoue, K; Matsuyama, H; Miyake, M; Nagao, K; Nakai, Y; Oyama, M; Ozono, S; Shimamoto, T; Shuin, T; Tsuzuki, T, 2018) |
| "PDD can increase the detection rate of bladder cancer, compared to NBI, by greater than 10%." | 5.62 | Comparison between 5-aminolevulinic acid photodynamic diagnosis and narrow-band imaging for bladder cancer detection. ( Abe, Y; Hagimoto, H; Kawakita, M; Kokubun, H; Kubota, M; Makita, N; Mine, Y; Murata, S; Tsutsumi, N; Yamasaki, T, 2021) |
| "Sixty-one patients with bladder cancer, confirmed histologically after the transurethral resection of a bladder tumor, were recruited as the bladder cancer group, and 50 outpatients without history of urothelial carcinoma or cancer-related findings were recruited as the control group." | 5.42 | Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Masaomi, K; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2015) |
| "The differences in the bladder cancer group were significantly greater than those in the control group (p < 0." | 5.42 | Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Masaomi, K; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2015) |
| "Urine samples from 58 patients with bladder cancer were centrifuged, and urine sediments were then treated with ALA." | 5.40 | Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Kuwada, M; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2014) |
| "Latent HPV infections at 0." | 5.35 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "The relatively high recurrence rate of genital warts can be attributed to the unsuccessful elimination of viruses in areas of subclinical and latent infection." | 5.35 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "Four patients with nonresectable bile duct cancer underwent cholangiography, cholangioscopy, and intraductal US before PDT." | 5.31 | Photodynamic therapy with 5-aminolevulinic acid is not effective in bile duct cancer. ( Apel, D; Arnold, JC; Jakobs, R; Riemann, JF; Rosenbaum, A; Zoepf, T, 2001) |
| "To confirm the reproducibility of the effectiveness and safety in photodynamic diagnosis of non-muscle-invasive bladder cancer using 5-aminolevulinic acid in a prospective multicenter non-randomized phase III trial." | 5.27 | Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study. ( Fujimoto, K; Furuse, H; Inoue, K; Matsuyama, H; Miyake, M; Nagao, K; Nakai, Y; Oyama, M; Ozono, S; Shimamoto, T; Shuin, T; Tsuzuki, T, 2018) |
| "Photodynamic diagnosis (PDD) of non-muscle-invasive bladder cancer (NMIBC) following transurethral administration of a hexalated form of 5-aminolevulinic acid (5-ALA), 5-ALA hexyl ester, is widely performed in Western countries." | 5.20 | Oral 5-aminolevulinic acid mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A randomized, double-blind, multicentre phase II/III study. ( Anai, S; Fujimoto, K; Fukuhara, H; Furuse, H; Hara, T; Hirao, Y; Inoue, K; Kai, F; Matsuyama, H; Narukawa, M; Oyama, M; Ozono, S; Shuin, T; Ueno, M, 2015) |
| " The use of 5-aminolevulinic acid as the photosensitising agent has been associated with side effects, specifically hypotension." | 5.17 | Oral 5-aminolevulinic acid induced Photodynamic Diagnostic Ureterorenoscopy--does the blood pressure require monitoring? ( Aboumarzouk, OM; Bondad, J; Kata, SG; Moseley, H, 2013) |
| "In 208 consecutive patients with superficial bladder cancer 328 endoscopies were performed to compare the sensitivity of white light and 5-aminolevulinic acid induced fluorescence endoscopy." | 5.09 | Is everything all right if nothing seems wrong? A simple method of assessing the diagnostic value of endoscopic procedures when a gold standard is absent. ( Kriegmair, M; Schneeweiss, S; Stepp, H, 1999) |
| "We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence." | 5.09 | Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy. ( Baumgartner, R; Hofstetter, A; Knuechel, R; Kriegmair, M; Stepp, H; Zaak, D, 1999) |
| "5-Aminolevulinic acid facilitates detection of neoplastic disease during transurethral resection of bladder cancer and increases the accuracy of diagnosis." | 5.09 | Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy. ( Baumgartner, R; Hofstetter, A; Knuechel, R; Kriegmair, M; Stepp, H; Zaak, D, 1999) |
| "1) To determine whether fluorescence cystoscopy after intravesical administration of 5-aminolevulinic acid (5-ALA) is more sensitive in detection of dysplasia and bladder cancer when compared with conventional cystoscopy." | 5.09 | Cystoscopic diagnosis of bladder cancer by intravesical instillation of 5-aminolevulinic acid induced porphyrin fluorescence--the Singapore experience. ( Cheng, CW; Lau, WK; Olivo, M; Tan, PH, 2000) |
| "The initial encouraging results using 5-aminolevulinic acid (5-ALA) induced fluorescence endoscopy (AFE) have promised a procedure with an outstanding sensitivity for the detection of early stage bladder cancer." | 5.09 | Endoscopic detection of transitional cell carcinoma with 5-aminolevulinic acid: results of 1012 fluorescence endoscopies. ( Baumgartner, R; Corvin, S; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Oberneder, R; Schneede, P; Stepp, H; Zaak, D, 2001) |
| " The usefulness of intracellularly accumulated endogenous protoporphyrin IX (PPIX), induced by 5-aminolevulinic acid (ALA), for diagnosis of early bladder cancer and the correlation with cystoscopic, microscopic, and fluorescence findings was investigated." | 5.07 | Fluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid. ( Baumgartner, R; Ehsan, A; Hofstädter, F; Hofstetter, A; Knuechel, R; Kriegmair, M; Lumper, W; Steinbach, P, 1994) |
| "We performed a systematic review and meta-analysis to address the (added) value of intraoperative 5-aminolevulinic acid (5-ALA)-guided resection of high-grade malignant gliomas compared with conventional neuronavigation-guided resection, with respect to diagnostic accuracy, extent of tumor resection, safety, and survival." | 4.89 | Intraoperative fluorescence-guided resection of high-grade malignant gliomas using 5-aminolevulinic acid-induced porphyrins: a systematic review and meta-analysis of prospective studies. ( Chen, X; Dong, X; Han, D; Li, H; Liu, H; Liu, Y; Shen, C; Shi, C; Teng, L; Wang, C; Wang, L; Wu, J; Yang, G; Zhao, S, 2013) |
| "Hexaminolevulinate (HAL) induced Protoporphyrin IX (PpIX) fluorescence is commonly used to differentiate cancer cells from normal cells in vivo, as for instance in blue light cystoscopy for bladder cancer diagnosis." | 4.02 | Improving hexaminolevulinate enabled cancer cell detection in liquid biopsy immunosensors. ( Chan, KM; Gleadle, J; Li, J; MacGregor, M; Michl, TD; Vasilev, K, 2021) |
| "To investigate the diagnostic accuracy of 5- aminolevulinic acid-mediated photodynamic diagnosis (ALA-PDD) for upper urinary tract tumor (UTUC) including carcinoma in situ (CIS) lesions using flexible fluorescence ureterorenoscopy." | 3.96 | 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence ureterorenoscopy for urinary upper tract urothelial carcinoma ∼Preliminary prospective single centre trial∼. ( Fukuhara, H; Furihata, M; Inoue, K; Kurabayashi, A; Murakami, K; Setuda, S; Takahashi, K; Tanaka, T, 2020) |
| "To compare fluorescence intensity of tumor specimens, as measured by a fluorescence-guided surgery microscope and a spectrometer, to evaluate tumor infiltration of dura mater around meningiomas with help of these 2 different 5-aminolevulinic acid (5-ALA)-based fluorescence tools, and to correlate fluorescence intensity with histopathologic data." | 3.85 | Fluorescence Behavior and Dural Infiltration of Meningioma Analyzed by 5-Aminolevulinic Acid-Based Fluorescence: Operating Microscope Versus Mini-Spectrometer. ( Beseoglu, K; Cornelius, JF; Felsberg, J; Fischer, I; Kamp, M; Knipps, J; Neumann, LM; Steiger, HJ, 2017) |
| "We evaluated the feasibility of photodynamic diagnosis of bladder cancer by spectrophotometric analysis of voided urine samples after extracorporeal treatment with 5-aminolevulinic acid (ALA)." | 3.81 | Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Masaomi, K; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2015) |
| "We demonstrated that protoporphyrin IX levels in urinary cells treated with ALA could be quantitatively detected by spectrophotometer in patients with bladder cancer." | 3.81 | Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Masaomi, K; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2015) |
| "To evaluate the use of 5-aminolevulinic acid (5-ALA) for the noninvasive detection of malignant gliomas by using in vivo magnetic resonance (MR) imaging in a mouse brain tumor model." | 3.80 | Malignant glioma: MR imaging by using 5-aminolevulinic acid in an animal model. ( Bishop, D; Cho, HR; Choi, SH; Doble, P; Han, MH; Hare, D; Kim, D; Kim, DH; Moon, WK; Park, CK, 2014) |
| "This study was undertaken to evaluate the clinical value of photodynamic diagnosis (PDD) with intravesical and oral instillation of 5-aminolevulinic acid (ALA) (ALA-PDD), and transurethral resection of bladder tumor (TURBT) guided by ALA-PDD (PDD-TURBT) for nonmuscle invasive bladder cancer." | 3.78 | Comparison between intravesical and oral administration of 5-aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer. ( Fukuhara, H; Furihata, M; Iiyama, T; Inoue, K; Kamada, M; Kurabayashi, A; Miyamura, M; Shimamoto, T; Shuin, T; Tanimura, M; Watanabe, H, 2012) |
| "Accurate determinations of 5-aminolevulinic acid (ALA) and porphobilinogen (PBG) in physiologic fluids are required for the diagnosis and therapeutic monitoring of acute porphyrias." | 3.77 | A LC-MS/MS method for the specific, sensitive, and simultaneous quantification of 5-aminolevulinic acid and porphobilinogen. ( Balwani, M; Bishop, D; Desnick, RJ; Yasuda, M; Yu, C; Zhang, J, 2011) |
| "To study the differential effects of bacillus Calmette-Guérin (BCG) and mitomycin C (MMC) intravesical therapy on the false-positive rate of PDD of bladder cancer." | 3.76 | Photodynamic diagnosis (5-aminolevulinic acid) of transitional cell carcinoma after bacillus Calmette-Guérin immunotherapy and mitomycin C intravesical therapy. ( Bosch, JL; Draga, RO; Grimbergen, MC; Jonges, TN; Kok, ET; van Swol, CF, 2010) |
| " In bladder cancer diagnosis, fluorescence-guided endoscopy with 5-aminolevulinic acid (5-ALA) has gained interest as a technique that can provide such spatial differentiation, thus improving early detection and more complete removal of superficial tumors." | 3.75 | Raman spectroscopy of bladder tissue in the presence of 5-aminolevulinic acid. ( Grimbergen, MC; Mahadevan-Jansen, A; Stone, N; Uff, J; van Moorselaar, RJ; van Swol, CF, 2009) |
| " The goal of this study is to investigate the usefulness of 5-aminolevulinic acid (ALA)-assisted in situ fluorescence diagnosis of subclinical lesion and latent HPV infection." | 3.74 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "Laryngeal lesions (N = 39; 21 after administration of delta-aminolevulinic acid (ALA)) were investigated with laser-induced fluorescence, and the results correlated to histopathologic grading in 4 groups: non/mild dysplasia (I), moderate dysplasia (II), severe dysplasia/cancer in situ (III), and carcinoma." | 3.74 | Fluorescence investigations to classify malignant laryngeal lesions in vivo. ( Andersson-Engels, S; Eker, C; Krogdahl, A; Rydell, R; Svanberg, K; Wahlberg, P, 2008) |
| "5-Aminolevulinic acid (ALA) or its derivative methyl 5-aminolevulinate (MAL) combined with folic acid was applied in nude mice bearing human colon adenocarcinoma." | 3.73 | The effect of folic acid on porphyrin synthesis in tumors and normal skin of mice treated with 5-aminolevulinic acid or methyl 5-aminolevulinate. ( Iani, V; Juzeniene, A; Ma, L; Moan, J; Steindal, AE, 2006) |
| "5-Aminolevulinic acid induced fluorescence endoscopy has outstanding sensitivity for detecting early stage bladder cancer." | 3.71 | Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. ( Baumgartner, R; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Schneede, P; Siebels, M; Stepp, H; Wagner, S; Zaak, D, 2001) |
| "In 25 cases (53 biopsies) of a history of or suspicion for bladder cancer 5-aminolevulinic acid induced fluorescence endoscopy and fluorescence image quantification were performed." | 3.71 | Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. ( Baumgartner, R; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Schneede, P; Siebels, M; Stepp, H; Wagner, S; Zaak, D, 2001) |
| "Our observations suggest that 5-aminolevulinic acid-induced porphyrin fluorescence may label malignant gliomas safely and accurately enough to enhance the completeness of tumor removal." | 3.70 | Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence. ( Fritsch, C; Goetz, AE; Goetz, C; Kiefmann, R; Reulen, HJ; Stepp, H; Stocker, S; Stummer, W; Wagner, S, 1998) |
| "Malignant gliomas accumulate fluorescing protoporphyrin IX intracellularly after exposure to 5-aminolevulinic acid, a metabolic precursor of haem." | 3.70 | Technical principles for protoporphyrin-IX-fluorescence guided microsurgical resection of malignant glioma tissue. ( Ehrhardt, A; Leonhard, M; Möller, G; Reulen, HJ; Stepp, H; Stummer, W, 1998) |
| "To determine the accuracy of the indicators for detecting lead poisoning." | 3.70 | [Re-assessment of indicators for screening lead poisoning]. ( Lin, G; Lü, L; Wang, Q; Xu, M; Zou, H, 1999) |
| "We determined whether the sensitivity of detecting dysplasia or early bladder cancer can be improved by 5-aminolevulinic acid induced porphyrin fluorescence." | 3.69 | Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. ( Baumgartner, R; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Stepp, H, 1996) |
| "5-Aminolevulinic acid (20 mg/kg) was orally administered 3 h before transurethral resection of bladder tumors using white light or fluorescent light." | 2.87 | Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study. ( Fujimoto, K; Furuse, H; Inoue, K; Matsuyama, H; Miyake, M; Nagao, K; Nakai, Y; Oyama, M; Ozono, S; Shimamoto, T; Shuin, T; Tsuzuki, T, 2018) |
| "5-Aminolevulinic acid was orally administered 3-14 hours before surgery using a dosage of 1 mg/kg, 4-9 hours using 10 mg/kg, and 9-16 hours using 10 mg/kg, respectively." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
| "With a prospective feasibility study, we aimed to analyse the effect of different time points for application and dosage of preoperative oral 5-aminolevulinic acid administration for photodynamic diagnosis of peritoneal metastases in ovarian cancer patients." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
| " 5-Aminolevulinic acid was orally administered 3-14 hours before surgery using a dosage of 1 mg/kg, 4-9 hours using 10 mg/kg, and 9-16 hours using 10 mg/kg, respectively." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
| " Orally applied 5-aminolevulinic acid with a dosage of 1 mg/kg revealed no detectable fluorescence." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
| " 5-Aminolevulinic acid should be used at a dosage of at least 10 mg/kg 4-9 hours preoperatively." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
| "In total, 26 patients suspected for ovarian cancer underwent intraoperative photodynamic diagnosis with 5-aminolevulinic acid." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
| "The sensitivity and specificity were 75." | 2.80 | Performance of 5-aminolevulinic-acid-based photodynamic diagnosis for radical prostatectomy. ( Fukuhara, H; Furihata, M; Inoue, K; Kurabayashi, A; Shuin, T, 2015) |
| "All 52 patients were diagnosed with prostate cancer by biopsy." | 2.80 | Performance of 5-aminolevulinic-acid-based photodynamic diagnosis for radical prostatectomy. ( Fukuhara, H; Furihata, M; Inoue, K; Kurabayashi, A; Shuin, T, 2015) |
| "Hypotension is a common occurrence after the ingestion of 5-ALA." | 2.78 | Oral 5-aminolevulinic acid induced Photodynamic Diagnostic Ureterorenoscopy--does the blood pressure require monitoring? ( Aboumarzouk, OM; Bondad, J; Kata, SG; Moseley, H, 2013) |
| "Hypotension was defined as <80% of the systolic or diastolic baseline blood pressure." | 2.78 | Oral 5-aminolevulinic acid induced Photodynamic Diagnostic Ureterorenoscopy--does the blood pressure require monitoring? ( Aboumarzouk, OM; Bondad, J; Kata, SG; Moseley, H, 2013) |
| "Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX was found as a valuable tool in the diagnosis of oral premalignancy." | 2.72 | Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. ( El-Maaytah, M; Hopper, C; Jerjes, W; Khalil, HS; MacRobert, AJ; Salih, V; Sharwani, A, 2006) |
| "Nineteen patients with localized prostate cancer were included in the study." | 2.72 | Photodynamic selectivity of 5-aminolevulinic acid to prostate cancer cells. ( Abdel-Gawad, O; El-Doray, AA; El-Mahdy, Ael-D; Hofstetter, A; Khoder, W; Sultan, SM, 2006) |
| "A major problem diagnosing bladder cancer using conventional white-light cystoscopy is that flat and tiny papillary neoplasms can be overlooked." | 2.70 | Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms. ( Chai, SE; Choi, HY; Hong, JH; Jeon, SS; Kang, I, 2001) |
| "A series of 62 patients with suspected bladder cancer were investigated by fluorescence cystoscopy." | 2.70 | Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms. ( Chai, SE; Choi, HY; Hong, JH; Jeon, SS; Kang, I, 2001) |
| "Though meningiomas are often benign and well circumscribed in nature, many are associated with recurrences and poor outcome because of their attachment to neurovascular nearby structures or invasion of adjacent venous sinuses or bone, forcing incomplete excision and deployment of further salvage therapy." | 2.53 | ALA-induced fluorescence image guided surgery of meningiomas: A meta-analyses. ( Eljamel, S; Foster, N, 2016) |
| "ALA-FIGS in meningiomas is very selective, highly sensitive, and improves the extent of surgical resection in meningiomas." | 2.53 | ALA-induced fluorescence image guided surgery of meningiomas: A meta-analyses. ( Eljamel, S; Foster, N, 2016) |
| "Bladder cancer is the most common tumor of the urinary tract, with a worldwide incidence of 8." | 2.49 | Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over. ( Ambrosini, E; Frea, B; Giona, S; Gontero, P; Gurioli, A; Oderda, M; Peraldo, F; Soria, F, 2013) |
| "Although bladder cancer occurs frequently, early diagnosis and complete removal of malignant lesions usually lead to good clinical outcomes." | 2.45 | Hexyl aminolevulinate fluorescence cystoscopy in bladder cancer. ( Kruck, S; Sievert, KD, 2009) |
| "In flat bladder cancer and carcinoma in situ, and in multifocal papillary cancer, some smaller lesions may be overlooked at cystoscopy." | 2.44 | Recent developments in fluorescence cystoscopy: do novel agents bring a benefit? ( Marberger, M; Schmidbauer, J, 2007) |
| "Bladder cancer is a frequent disease and represents the second most common genitourinary neoplasm." | 2.44 | [Fluorescence cystoscopy at bladder cancer: present trials]. ( Burger, M; Karl, A; Knuechel, R; Stepp, H; Stief, C; Tilki, D; Tritschler, S; Zaak, D, 2007) |
| "PDD can increase the detection rate of bladder cancer, compared to NBI, by greater than 10%." | 1.62 | Comparison between 5-aminolevulinic acid photodynamic diagnosis and narrow-band imaging for bladder cancer detection. ( Abe, Y; Hagimoto, H; Kawakita, M; Kokubun, H; Kubota, M; Makita, N; Mine, Y; Murata, S; Tsutsumi, N; Yamasaki, T, 2021) |
| "The ability to detect and diagnose bladder cancer early and precisely is crucial for effective treatment." | 1.56 | Evaluation of autofluorescence and photodynamic diagnosis in assessment of bladder lesions. ( Aebisher, D; Bochynek, K; Cieślar, G; Gasiorek, M; Kawczyk-Krupka, A, 2020) |
| "The current blood test for detecting prostate cancers measures prostate-specific antigen." | 1.56 | Plasma enabled devices for the selective capture and photodynamic identification of prostate cancer cells. ( Butler, L; Chan, KM; Gleadle, JM; Li, J; MacGregor, M; McNicholas, K; Ostrikov, K; Rouget, J; Shirazi, HS; Vasilev, K, 2020) |
| "Prostate cancer is the second most common cancer in men and the second leading cause of male cancer deaths." | 1.56 | Plasma enabled devices for the selective capture and photodynamic identification of prostate cancer cells. ( Butler, L; Chan, KM; Gleadle, JM; Li, J; MacGregor, M; McNicholas, K; Ostrikov, K; Rouget, J; Shirazi, HS; Vasilev, K, 2020) |
| "Sensitivity and specificity were calculated for Gd-DTPA MRI, PWI, met-PET, and 5-ALA according to the histology of specimen." | 1.51 | Diagnostic accuracy of intraoperative perfusion-weighted MRI and 5-aminolevulinic acid in relation to contrast-enhanced intraoperative MRI and ( Beer, AJ; Coburger, J; Eberhardt, N; König, R; Pala, A; Reske, SN; Scheuerle, A; Schmitz, B; Wirtz, CR, 2019) |
| "Patients with suspected bladder cancer (positive cytology with negative WLC) or history of previous high-grade NMIBC or CIS were included in the study." | 1.46 | Blue light cystoscopy with hexylaminolevulinate: Our 7 years experience. ( Beatrici, V; Cantoro, D; Cantoro, U; Cervelli, B; Cicetti, A; Gabrielloni, G; Lacetera, V; Milella, D; Montesi, L; Montesi, M; Morcellini, R; Parri, G; Recanatini, E, 2017) |
| "To evaluate the residual tumor rate, the bladder was inspected after its removal and normal appearing mucosa sampled for histologic analysis." | 1.46 | Diagnostic Accuracy of Hexaminolevulinate in a Cohort of Patients Undergoing Radical Cystectomy. ( Alba, S; Buscarini, M; Carrieri, G; Cormio, L; Di Stasi, S; Gallone, MF; Minafra, P; Pagliarulo, V; Petitti, T, 2017) |
| "Sensitivity and specificity was calculated." | 1.42 | Effectiveness of hexaminolevulinate fluorescence cystoscopy for the diagnosis of non-muscle-invasive bladder cancer in daily clinical practice: a Spanish multicentre observational study. ( Abascal, JM; Abascal, R; Burgués, JP; Cabrera, JA; Conde, G; Gutiérrez, C; Hernández, C; Herranz, F; Iborra, I; Oliva, J; Palou, J; Rioja, C; Rodríguez, O; Solsona, E, 2015) |
| "We evaluated the detection rate of bladder cancer lesions by WLC and BLC with hexaminolevulinate, overall and by tumour stage and compared with histological examination of the biopsied lesions." | 1.42 | Effectiveness of hexaminolevulinate fluorescence cystoscopy for the diagnosis of non-muscle-invasive bladder cancer in daily clinical practice: a Spanish multicentre observational study. ( Abascal, JM; Abascal, R; Burgués, JP; Cabrera, JA; Conde, G; Gutiérrez, C; Hernández, C; Herranz, F; Iborra, I; Oliva, J; Palou, J; Rioja, C; Rodríguez, O; Solsona, E, 2015) |
| "Sixty-one patients with bladder cancer, confirmed histologically after the transurethral resection of a bladder tumor, were recruited as the bladder cancer group, and 50 outpatients without history of urothelial carcinoma or cancer-related findings were recruited as the control group." | 1.42 | Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Masaomi, K; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2015) |
| "The differences in the bladder cancer group were significantly greater than those in the control group (p < 0." | 1.42 | Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Masaomi, K; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2015) |
| "Five-aminolevulinic acid (ALA) has received much attention recently as a new-generation photosensitive substance for photodynamic diagnosis (PDD)." | 1.40 | Photodynamic diagnosis using 5-aminolevulinic acid during gastrectomy for gastric cancer. ( Fukuhara, H; Hanazaki, K; Inoue, K; Kitagawa, H; Kobayashi, M; Maeda, H; Namikawa, T; Shiga, M; Shuin, T; Uemura, S, 2014) |
| "Urine samples from 58 patients with bladder cancer were centrifuged, and urine sediments were then treated with ALA." | 1.40 | Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Kuwada, M; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2014) |
| "Non-melanoma skin cancer is the most common cancer lesion worldwide." | 1.40 | Identification of skin lesions through aminolaevulinic acid-mediated photodynamic detection. ( Andrade, CT; Bagnato, VS; Kurachi, C; Salvio, AG; Vollet-Filho, JD, 2014) |
| "Past attempts at detecting prostate cancer (PCa) cells in voided urine by traditional cytology have been impeded by undesirably low sensitivities but high specificities." | 1.40 | Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Hirayama, A; Kuwada, M; Miyake, M; Nakai, Y; Tanaka, N; Yoshida, K, 2014) |
| "The mean number of metastases detected by the PDD was significantly higher than that of white light for FT821 (p=0." | 1.37 | 5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor. ( Ali, AH; Kakiuchi, S; Kenzaki, K; Kondo, K; Matsuoka, H; Nakagawa, Y; Sakiyama, S; Sekido, Y; Sone, S; Takizawa, H; Tangoku, A; Toba, H, 2011) |
| "Latent HPV infections at 0." | 1.35 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "The relatively high recurrence rate of genital warts can be attributed to the unsuccessful elimination of viruses in areas of subclinical and latent infection." | 1.35 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "The chemical diagnosis of tyrosinemia type I generally involves the detection of succinylacetone (SA) in patient urine." | 1.33 | Stability of 5-aminolevulinic acid on dried urine filter paper for a diagnostic marker of tyrosinemia type I. ( Inoue, Y; Kuhara, T; Ohse, M; Shinka, T, 2005) |
| "Thirty-six patients with epithelial ovarian cancer and two patients suffering from fallopian tube carcinoma underwent a laparoscopic second-look procedure 5 hours after the application of ALA." | 1.33 | Fluorescence staining of human ovarian cancer tissue following application of 5-aminolevulinic acid: fluorescence microscopy studies. ( Diddens, HC; Diedrich, K; Holl-Ulrich, K; Hüttmann, G; Küpker, W; Löning, MC; Löning, U, 2006) |
| "Longstanding ulcerative colitis (UC), especially in the presence of epithelial dysplasia, is associated with an increased risk of developing cancer." | 1.32 | Fluorescence endoscopy for the detection of low and high grade dysplasia in ulcerative colitis using systemic or local 5-aminolaevulinic acid sensitisation. ( Endlicher, E; Freunek, G; Knüchel, R; Messmann, H; Rümmele, P; Schölmerich, J, 2003) |
| "The dosage of 20 mg/kg body weight of 5-ALA is feasible for fluorescence diagnosis of nonpigmented endometriosis." | 1.32 | Detection of nonpigmented endometriotic lesions with 5-aminolevulinic acid-induced fluorescence. ( Buchweitz, O; Kiesel, L; Staebler, A; Wülfing, P, 2004) |
| "It will be the aim of further investigations to verify the optimal time of incubation and dosing of systemical 5-ALA application to enhance fluorescence contrasts and set the basis for fluorescence guided resections." | 1.31 | [Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid]. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Leunig, A, 2002) |
| "Four patients with nonresectable bile duct cancer underwent cholangiography, cholangioscopy, and intraductal US before PDT." | 1.31 | Photodynamic therapy with 5-aminolevulinic acid is not effective in bile duct cancer. ( Apel, D; Arnold, JC; Jakobs, R; Riemann, JF; Rosenbaum, A; Zoepf, T, 2001) |
| "This was first shown for cancer of the bladder." | 1.31 | [Fluorescent endoscopy superior to white light endoscopy. Detecting cancers of the urinary bladder earlier]. ( Zaak, D, 2002) |
| "The prognosis of superficial bladder cancer in terms of recurrence and disease progression is related to bladder tumor multiplicity and the presence of concomitant "plane" tumors such as high-grade dysplasia and carcinoma in situ." | 1.30 | Clinical assessment of fluorescence cytoscopy during transurethral bladder resection in superficial bladder cancer. ( Forrer, M; Graber, P; Guillou, L; Jichlinski, P; Leisinger, HJ; Mizeret, J; Oswald, M; Schmidlin, F; Van den Bergh, H; Wagnières, G, 1997) |
| "The prognosis of superficial bladder cancer in terms of local recurrence and transformation into invasive cancer is related to the multiplicity of tumor sites and the concomitant presence of "flat" tumours, such as dysplasia and carcinoma in situ." | 1.30 | [The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder]. ( Forrer, M; Graber, P; Guillou, L; Jichlinski, P; Leisinger, HJ; Mizeret, J; Schmidlin, F; Van den Bergh, H; Wagniéres, G, 1997) |
| "Sixteen patients with papillary bladder cancer, and CIS and dysplasia were given low-dose ALA." | 1.30 | Fluorescence detection of flat transitional cell carcinoma after intravesical instillation of aminolevulinic acid. ( Baert, L; D'Hallewin, MA; Vanherzeele, H, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 31 (14.69) | 18.2507 |
| 2000's | 104 (49.29) | 29.6817 |
| 2010's | 67 (31.75) | 24.3611 |
| 2020's | 9 (4.27) | 2.80 |
| Authors | Studies |
|---|---|
| Guder, WK | 1 |
| Hartmann, W | 1 |
| Buhles, C | 1 |
| Burdack, M | 1 |
| Busch, M | 1 |
| Dünker, N | 1 |
| Hardes, J | 1 |
| Dirksen, U | 1 |
| Bauer, S | 1 |
| Streitbürger, A | 1 |
| Hirao, M | 2 |
| Hosui, A | 2 |
| Mimura, A | 3 |
| Ohnishi, K | 2 |
| Tanimoto, T | 2 |
| Okahara, T | 1 |
| Sueyoshi, Y | 1 |
| Goto, T | 1 |
| Yamada, T | 2 |
| Hiramatsu, N | 2 |
| Kusumoto, Y | 1 |
| Yamaguchi, T | 1 |
| Miwa, H | 2 |
| Fukuhara, H | 9 |
| Kurabayashi, A | 3 |
| Furihata, M | 4 |
| Setuda, S | 1 |
| Takahashi, K | 3 |
| Murakami, K | 1 |
| Tanaka, T | 5 |
| Inoue, K | 12 |
| Bochynek, K | 1 |
| Aebisher, D | 1 |
| Gasiorek, M | 1 |
| Cieślar, G | 1 |
| Kawczyk-Krupka, A | 1 |
| Shirazi, HS | 1 |
| Chan, KM | 2 |
| Rouget, J | 1 |
| Ostrikov, K | 1 |
| McNicholas, K | 1 |
| Li, J | 2 |
| Butler, L | 1 |
| Gleadle, JM | 1 |
| Vasilev, K | 2 |
| MacGregor, M | 2 |
| Gleadle, J | 1 |
| Michl, TD | 1 |
| Lacetera, V | 1 |
| Cantoro, U | 1 |
| Montesi, L | 1 |
| Cantoro, D | 1 |
| Cervelli, B | 1 |
| Cicetti, A | 1 |
| Gabrielloni, G | 1 |
| Milella, D | 1 |
| Montesi, M | 1 |
| Morcellini, R | 1 |
| Parri, G | 1 |
| Recanatini, E | 1 |
| Beatrici, V | 1 |
| Yano, H | 1 |
| Nakayama, N | 1 |
| Ohe, N | 1 |
| Miwa, K | 1 |
| Shinoda, J | 1 |
| Iwama, T | 1 |
| Knipps, J | 1 |
| Beseoglu, K | 1 |
| Kamp, M | 1 |
| Fischer, I | 1 |
| Felsberg, J | 1 |
| Neumann, LM | 1 |
| Steiger, HJ | 2 |
| Cornelius, JF | 2 |
| Pala, A | 2 |
| Reske, SN | 1 |
| Eberhardt, N | 1 |
| Scheuerle, A | 2 |
| König, R | 2 |
| Schmitz, B | 1 |
| Beer, AJ | 1 |
| Wirtz, CR | 2 |
| Coburger, J | 2 |
| Nakai, Y | 4 |
| Tsuzuki, T | 1 |
| Shimamoto, T | 2 |
| Shuin, T | 9 |
| Nagao, K | 1 |
| Matsuyama, H | 2 |
| Oyama, M | 2 |
| Furuse, H | 2 |
| Ozono, S | 2 |
| Miyake, M | 4 |
| Fujimoto, K | 5 |
| Raharja, PAR | 1 |
| Hamid, ARAH | 1 |
| Mochtar, CA | 1 |
| Umbas, R | 1 |
| Yamamichi, G | 1 |
| Nakata, W | 1 |
| Tani, M | 1 |
| Tsujimura, G | 1 |
| Tsujimoto, Y | 1 |
| Nin, M | 1 |
| Tsujihata, M | 1 |
| Konecki, T | 1 |
| Kutwin, P | 1 |
| Łowicki, R | 1 |
| Juszczak, AB | 1 |
| Jabłonowski, Z | 1 |
| Ferré, A | 1 |
| Cordonnier, C | 1 |
| Demailly, M | 1 |
| Hakami, F | 1 |
| Sevestre, H | 1 |
| Saint, F | 1 |
| Hirano, T | 1 |
| Hagiya, Y | 3 |
| Matsumoto, K | 1 |
| Okura, I | 3 |
| Ogura, S | 4 |
| Bondad, J | 1 |
| Aboumarzouk, OM | 2 |
| Moseley, H | 3 |
| Kata, SG | 2 |
| Zhao, S | 1 |
| Wu, J | 1 |
| Wang, C | 1 |
| Liu, H | 1 |
| Dong, X | 1 |
| Shi, C | 2 |
| Liu, Y | 1 |
| Teng, L | 1 |
| Han, D | 1 |
| Chen, X | 1 |
| Yang, G | 1 |
| Wang, L | 1 |
| Shen, C | 1 |
| Li, H | 1 |
| Soria, F | 1 |
| Gurioli, A | 1 |
| Peraldo, F | 1 |
| Oderda, M | 1 |
| Giona, S | 1 |
| Ambrosini, E | 1 |
| Frea, B | 1 |
| Gontero, P | 1 |
| Valdes, PA | 3 |
| Bekelis, K | 1 |
| Harris, BT | 3 |
| Wilson, BC | 3 |
| Leblond, F | 2 |
| Kim, A | 3 |
| Simmons, NE | 1 |
| Erkmen, K | 1 |
| Paulsen, KD | 3 |
| Roberts, DW | 3 |
| Widhalm, G | 1 |
| Kiesel, B | 1 |
| Woehrer, A | 1 |
| Traub-Weidinger, T | 1 |
| Preusser, M | 1 |
| Marosi, C | 1 |
| Prayer, D | 1 |
| Hainfellner, JA | 1 |
| Knosp, E | 1 |
| Wolfsberger, S | 1 |
| Namikawa, T | 1 |
| Uemura, S | 1 |
| Shiga, M | 1 |
| Maeda, H | 1 |
| Kitagawa, H | 1 |
| Kobayashi, M | 1 |
| Hanazaki, K | 1 |
| Maździarz, A | 1 |
| Zielińska, A | 1 |
| Alkhalayla, H | 1 |
| Spiewankiewicz, B | 2 |
| Ota, U | 2 |
| Ishizuka, M | 3 |
| Kawada, C | 1 |
| Penjweini, R | 1 |
| Loew, HG | 1 |
| Breit, P | 1 |
| Kratky, KW | 1 |
| Della Puppa, A | 1 |
| Rustemi, O | 1 |
| Gioffrè, G | 1 |
| Troncon, I | 1 |
| Lombardi, G | 1 |
| Rolma, G | 1 |
| Sergi, M | 1 |
| Munari, M | 1 |
| Cecchin, D | 1 |
| Gardiman, MP | 1 |
| Scienza, R | 1 |
| Anai, S | 4 |
| Tatsumi, Y | 2 |
| Kuwada, M | 2 |
| Onishi, S | 2 |
| Chihara, Y | 3 |
| Tanaka, N | 3 |
| Hirao, Y | 4 |
| Feizy, J | 1 |
| Beheshti, HR | 1 |
| Fahim, NK | 1 |
| Janati, SS | 1 |
| Davari, G | 1 |
| Cho, HR | 1 |
| Kim, DH | 1 |
| Kim, D | 1 |
| Doble, P | 1 |
| Bishop, D | 2 |
| Hare, D | 1 |
| Park, CK | 1 |
| Moon, WK | 1 |
| Han, MH | 1 |
| Choi, SH | 1 |
| Andrade, CT | 1 |
| Vollet-Filho, JD | 1 |
| Salvio, AG | 1 |
| Bagnato, VS | 1 |
| Kurachi, C | 1 |
| Hirayama, A | 1 |
| Yoshida, K | 1 |
| Slotty, PJ | 1 |
| Kamp, MA | 1 |
| Schneiderhan, TM | 1 |
| El-Khatib, M | 1 |
| Vansevičiūtė, R | 2 |
| Venius, J | 2 |
| Letautienė, S | 2 |
| Bosseila, M | 1 |
| Mahgoub, D | 1 |
| El-Sayed, A | 1 |
| Salama, D | 1 |
| Abd El-Moneim, M | 1 |
| Al-Helf, F | 1 |
| Palou, J | 1 |
| Hernández, C | 1 |
| Solsona, E | 1 |
| Abascal, R | 1 |
| Burgués, JP | 1 |
| Rioja, C | 1 |
| Cabrera, JA | 1 |
| Gutiérrez, C | 1 |
| Rodríguez, O | 1 |
| Iborra, I | 1 |
| Herranz, F | 1 |
| Abascal, JM | 1 |
| Conde, G | 1 |
| Oliva, J | 1 |
| Masaomi, K | 1 |
| Rouprêt, M | 1 |
| Malavaud, B | 1 |
| Molinier, L | 1 |
| Leleu, H | 1 |
| Blachier, M | 1 |
| Marteau, F | 1 |
| Yeh, SC | 1 |
| Sahli, S | 1 |
| Andrews, DW | 1 |
| Patterson, MS | 2 |
| Armstrong, D | 1 |
| Provias, J | 1 |
| Fang, Q | 1 |
| Hayashi, M | 1 |
| Nakajima, M | 2 |
| Isomoto, H | 1 |
| Nanashima, A | 1 |
| Senoo, T | 1 |
| Ogiwara, K | 1 |
| Hashisako, M | 1 |
| Ohnita, K | 1 |
| Yamaguchi, N | 1 |
| Kunizaki, M | 1 |
| Hidaka, S | 1 |
| Fukuda, H | 1 |
| Ishii, H | 1 |
| Matsushima, K | 1 |
| Minami, H | 1 |
| Akazawa, Y | 1 |
| Takeshima, F | 1 |
| Fukuoka, J | 1 |
| Nagayasu, T | 1 |
| Nakao, K | 1 |
| Kai, F | 1 |
| Hara, T | 1 |
| Ueno, M | 1 |
| Narukawa, M | 1 |
| Žukovskaja, O | 1 |
| Kanopienė, D | 1 |
| Rotomskis, R | 1 |
| Zreik, A | 1 |
| Somani, B | 1 |
| Ahmad, S | 1 |
| Nabi, G | 1 |
| Buist, R | 1 |
| Goodman, C | 1 |
| Chlosta, P | 1 |
| Golabek, T | 1 |
| Guyotat, J | 1 |
| Pallud, J | 1 |
| Armoiry, X | 1 |
| Pavlov, V | 1 |
| Metellus, P | 1 |
| Kürten, V | 1 |
| Neumann, NJ | 2 |
| Frank, J | 1 |
| Kaibori, M | 2 |
| Matsui, K | 1 |
| Ishizaki, M | 1 |
| Iida, H | 1 |
| Okumura, T | 1 |
| Sakaguchi, T | 1 |
| Ikeura, T | 2 |
| Asano, H | 1 |
| Kon, M | 1 |
| Foster, N | 1 |
| Eljamel, S | 1 |
| Nakae, S | 1 |
| Murayama, K | 1 |
| Sasaki, H | 1 |
| Kumon, M | 1 |
| Nishiyama, Y | 1 |
| Ohba, S | 1 |
| Adachi, K | 1 |
| Nagahisa, S | 1 |
| Hayashi, T | 1 |
| Inamasu, J | 1 |
| Abe, M | 1 |
| Hasegawa, M | 1 |
| Hirose, Y | 1 |
| Hillemanns, P | 2 |
| Wimberger, P | 1 |
| Reif, J | 1 |
| Stepp, H | 24 |
| Klapdor, R | 1 |
| Pagliarulo, V | 1 |
| Alba, S | 1 |
| Gallone, MF | 1 |
| Di Stasi, S | 1 |
| Cormio, L | 1 |
| Petitti, T | 1 |
| Buscarini, M | 1 |
| Minafra, P | 1 |
| Carrieri, G | 1 |
| Thal, D | 1 |
| Giuntini, F | 1 |
| Bourré, L | 1 |
| Macrobert, AJ | 3 |
| Wilson, M | 1 |
| Eggleston, IM | 1 |
| Neus, S | 1 |
| Gambichler, T | 2 |
| Bechara, FG | 1 |
| Wöhl, S | 1 |
| Lehmann, P | 2 |
| Ray, ER | 1 |
| Chatterton, K | 1 |
| Khan, MS | 1 |
| Thomas, K | 2 |
| Chandra, A | 1 |
| O'Brien, TS | 1 |
| Sardh, E | 1 |
| Harper, P | 1 |
| Andersson, DE | 1 |
| Floderus, Y | 1 |
| Egawa, S | 1 |
| Wang, HW | 1 |
| Wang, XL | 1 |
| Zhang, LL | 1 |
| Guo, MX | 1 |
| Huang, Z | 1 |
| Eljamel, MS | 2 |
| Leese, G | 1 |
| Grimbergen, MC | 4 |
| van Swol, CF | 4 |
| van Moorselaar, RJ | 2 |
| Uff, J | 1 |
| Mahadevan-Jansen, A | 1 |
| Stone, N | 2 |
| O'Brien, T | 1 |
| Sievert, KD | 1 |
| Kruck, S | 1 |
| Schmidbauer, J | 2 |
| Remzi, M | 1 |
| Klatte, T | 1 |
| Waldert, M | 1 |
| Mauermann, J | 1 |
| Susani, M | 1 |
| Marberger, M | 2 |
| Draga, RO | 1 |
| Kok, ET | 1 |
| Jonges, TN | 1 |
| Bosch, JL | 2 |
| Szafińska-Dolata, A | 1 |
| Kedzia, W | 1 |
| Szafiński, A | 1 |
| Józefiak, A | 1 |
| Spaczyński, M | 1 |
| Kuno, T | 1 |
| Hamaguchi, T | 1 |
| Fukata, S | 1 |
| Karashima, T | 1 |
| Kamada, M | 2 |
| Sakakura, N | 1 |
| Kasahara, K | 1 |
| Watanabe, H | 2 |
| Kozai, T | 1 |
| Yasuda, M | 2 |
| Kataoka, S | 1 |
| Tanimura, M | 2 |
| Atsushi, K | 1 |
| Kendall, C | 1 |
| Verdaasdonk, RM | 1 |
| Haedersdal, M | 1 |
| Sakamoto, FH | 1 |
| Farinelli, WA | 1 |
| Doukas, AG | 1 |
| Tam, J | 1 |
| Anderson, RR | 1 |
| Liutkeviciūte-Navickiene, J | 1 |
| Mordas, A | 1 |
| Simkute, S | 1 |
| Bloznelyte-Plesniene, L | 1 |
| Kausch, I | 1 |
| Sommerauer, M | 1 |
| Montorsi, F | 1 |
| Stenzl, A | 1 |
| Jacqmin, D | 1 |
| Jichlinski, P | 5 |
| Jocham, D | 3 |
| Ziegler, A | 1 |
| Vonthein, R | 1 |
| Silva, FR | 1 |
| Bellini, MH | 1 |
| Nabeshima, CT | 1 |
| Schor, N | 1 |
| Vieira, ND | 1 |
| Courrol, LC | 1 |
| Ali, AH | 1 |
| Takizawa, H | 1 |
| Kondo, K | 1 |
| Matsuoka, H | 1 |
| Toba, H | 1 |
| Nakagawa, Y | 1 |
| Kenzaki, K | 1 |
| Sakiyama, S | 1 |
| Kakiuchi, S | 1 |
| Sekido, Y | 1 |
| Sone, S | 1 |
| Tangoku, A | 1 |
| Suzuki, T | 1 |
| Numata, T | 1 |
| Shibuya, M | 1 |
| Kraft, M | 1 |
| Betz, CS | 5 |
| Leunig, A | 6 |
| Arens, C | 1 |
| Alsarra, IA | 1 |
| Yassin, AE | 1 |
| Abdel-Hamid, M | 1 |
| Alanazi, FK | 1 |
| Aljuffali, IA | 1 |
| Geavlete, B | 1 |
| Multescu, R | 1 |
| Georgescu, D | 1 |
| Jecu, M | 1 |
| Stanescu, F | 1 |
| Geavlete, P | 1 |
| Iiyama, T | 1 |
| Miyamura, M | 1 |
| Zhang, J | 1 |
| Desnick, RJ | 1 |
| Balwani, M | 1 |
| Yu, C | 1 |
| Brantsch, M | 1 |
| Niu, C | 1 |
| Moses, ZB | 1 |
| Tosteson, TD | 1 |
| Conde, OM | 1 |
| Mizokami, Y | 1 |
| Honda, K | 1 |
| Tabata, K | 1 |
| Kamachi, T | 1 |
| Abe, F | 1 |
| van der Beek, N | 1 |
| de Leeuw, J | 1 |
| Demmendal, C | 1 |
| Bjerring, P | 1 |
| Neumann, HA | 1 |
| Roessler, K | 1 |
| Becherer, A | 1 |
| Donat, M | 1 |
| Cejna, M | 1 |
| Zachenhofer, I | 1 |
| Espinas, NA | 1 |
| Kobayashi, K | 1 |
| Takahashi, S | 1 |
| Mochizuki, N | 1 |
| Masuda, T | 1 |
| Benton, CM | 2 |
| Couchman, L | 2 |
| Marsden, JT | 2 |
| Rees, DC | 2 |
| Moniz, C | 2 |
| Lim, CK | 3 |
| Venturini, M | 1 |
| Sala, R | 1 |
| Gonzàlez, S | 1 |
| Calzavara-Pinton, PG | 1 |
| Marti, A | 1 |
| Leisinger, HJ | 4 |
| Zaak, D | 10 |
| Hungerhuber, E | 2 |
| Schneede, P | 7 |
| Frimberger, D | 4 |
| Corvin, S | 2 |
| Schmeller, N | 3 |
| Kriegmair, M | 10 |
| Hofstetter, A | 15 |
| Knuechel, R | 9 |
| Knöchel, R | 1 |
| Zheng, W | 2 |
| Soo, KC | 2 |
| Sivanandan, R | 1 |
| Olivo, M | 3 |
| Gamarra, F | 2 |
| Wagner, S | 5 |
| Al-Batran, S | 1 |
| Maier, I | 1 |
| Castro, M | 1 |
| Hautmann, H | 2 |
| Bergner, A | 1 |
| Baumgartner, R | 16 |
| Huber, RM | 2 |
| Brand, S | 1 |
| Wang, TD | 1 |
| Schomacker, KT | 2 |
| Poneros, JM | 1 |
| Lauwers, GY | 1 |
| Compton, CC | 1 |
| Pedrosa, MC | 1 |
| Nishioka, NS | 1 |
| Kauppinen, R | 1 |
| von und zu Fraunberg, M | 1 |
| D'Hallewin, MA | 2 |
| Bezdetnaya, L | 1 |
| Guillemin, F | 1 |
| Heinrich, P | 1 |
| Janda, P | 2 |
| Chan, JK | 1 |
| Monk, BJ | 1 |
| Cuccia, D | 1 |
| Pham, H | 1 |
| Kimel, S | 1 |
| Gu, M | 1 |
| Hammer-Wilson, MJ | 1 |
| Liaw, LH | 2 |
| Osann, K | 2 |
| DiSaia, PJ | 1 |
| Berns, M | 1 |
| Tromberg, B | 1 |
| Tadir, Y | 2 |
| Charoenbanpachon, S | 1 |
| Krasieva, T | 1 |
| Ebihara, A | 1 |
| Wilder-Smith, P | 1 |
| Tauber, S | 3 |
| Liedl, B | 2 |
| Liesmann, F | 1 |
| Lüdicke, F | 1 |
| Gabrecht, T | 1 |
| Lange, N | 2 |
| Wagnières, G | 4 |
| Van Den Bergh, H | 4 |
| Berclaz, L | 1 |
| Major, AL | 2 |
| Guillou, L | 3 |
| Karlsen, SJ | 1 |
| Malmström, PU | 1 |
| Brennhovd, B | 1 |
| Johansson, E | 1 |
| Gärtner, T | 1 |
| Messmann, H | 4 |
| Endlicher, E | 3 |
| Freunek, G | 1 |
| Rümmele, P | 2 |
| Schölmerich, J | 4 |
| Knüchel, R | 8 |
| Jonges, TG | 1 |
| Boon, TA | 1 |
| Zuijderhoudt, FM | 1 |
| Weykamp, CW | 1 |
| Willems, HL | 1 |
| Csanády, M | 1 |
| Kiss, JG | 1 |
| Iván, L | 1 |
| Jóri, J | 1 |
| Czigner, J | 1 |
| Stummer, W | 3 |
| Reulen, HJ | 3 |
| Novotny, A | 1 |
| Tonn, JC | 1 |
| Akoel, KM | 1 |
| Welfel, J | 1 |
| Gottwald, L | 1 |
| Suzin, J | 1 |
| Banerjee, B | 1 |
| Frei, KA | 1 |
| Bonel, HM | 1 |
| Frick, H | 1 |
| Walt, H | 1 |
| Steiner, RA | 1 |
| Hausmann, F | 1 |
| Rath, HC | 1 |
| Krieg, RC | 1 |
| Löning, M | 1 |
| Diddens, H | 1 |
| Küpker, W | 2 |
| Diedrich, K | 2 |
| Hüttmann, G | 2 |
| Zumbraegel, A | 1 |
| Bichler, KH | 1 |
| Krause, FS | 1 |
| Feil, G | 1 |
| Nelde, HJ | 1 |
| Song, JM | 1 |
| Kasili, PM | 1 |
| Griffin, GD | 1 |
| Vo-Dinh, T | 1 |
| Daniltchenko, D | 1 |
| Riedl, C | 1 |
| Koenig, F | 2 |
| Daha, LK | 1 |
| Sachs, M | 1 |
| Schnorr, D | 1 |
| Sabban, F | 1 |
| Collinet, P | 1 |
| Cosson, M | 1 |
| Mordon, S | 1 |
| Buchweitz, O | 2 |
| Wülfing, P | 1 |
| Staebler, A | 2 |
| Kiesel, L | 2 |
| Nowakowski, Z | 1 |
| Stelmachów, J | 1 |
| Gerulewicz, G | 1 |
| Lipiński, MI | 1 |
| Jeromin, LM | 1 |
| Shinka, T | 1 |
| Ohse, M | 1 |
| Inoue, Y | 1 |
| Kuhara, T | 1 |
| Witjes, F | 1 |
| Zeylemaker, B | 1 |
| van Moorselaar, J | 1 |
| Grimm, MO | 1 |
| Muschter, R | 1 |
| Popken, G | 1 |
| König, F | 1 |
| Kurth, KH | 1 |
| Kang, MS | 1 |
| Kim, DM | 1 |
| Kim, JS | 1 |
| Jeong, JH | 1 |
| Ramstad, S | 1 |
| Le Anh-Vu, N | 1 |
| Johnsson, A | 1 |
| Dysart, JS | 1 |
| Sharwani, A | 1 |
| Jerjes, W | 1 |
| Salih, V | 1 |
| El-Maaytah, M | 1 |
| Khalil, HS | 1 |
| Hopper, C | 1 |
| Löning, MC | 1 |
| Diddens, HC | 1 |
| Holl-Ulrich, K | 1 |
| Löning, U | 1 |
| Utsuki, S | 1 |
| Oka, H | 1 |
| Sato, S | 1 |
| Suzuki, S | 1 |
| Shimizu, S | 1 |
| Tanaka, S | 1 |
| Fujii, K | 1 |
| Meier, R | 1 |
| Bone, A | 1 |
| Stief, C | 3 |
| Tio, J | 1 |
| Ma, L | 1 |
| Steindal, AE | 1 |
| Juzeniene, A | 1 |
| Iani, V | 1 |
| Moan, J | 1 |
| Arai, T | 1 |
| Tani, S | 1 |
| Isoshima, A | 1 |
| Nagashima, H | 1 |
| Joki, T | 1 |
| Takahashi-Fujigasaki, J | 1 |
| Abe, T | 1 |
| Sailer, R | 1 |
| Strauss, WS | 1 |
| Wagner, M | 1 |
| Emmert, H | 1 |
| Schneckenburger, H | 1 |
| Hartmann, A | 1 |
| Karl, A | 2 |
| Tritschler, S | 2 |
| Cunderlíková, B | 1 |
| Wahlqvist, R | 1 |
| Berner, A | 1 |
| Vasovic, V | 1 |
| Warloe, T | 1 |
| Nesland, JM | 1 |
| Peng, Q | 1 |
| Pichler, JP | 1 |
| Won, Y | 1 |
| Hong, SH | 1 |
| Yu, HY | 1 |
| Kwon, YH | 1 |
| Yun, SJ | 1 |
| Lee, SC | 1 |
| Lee, JB | 1 |
| Tilki, D | 1 |
| Burger, M | 1 |
| Denzinger, S | 1 |
| Rössler, W | 1 |
| Otto, W | 1 |
| Forster, TH | 1 |
| Wyler, S | 1 |
| Ruszat, R | 1 |
| Gasser, TC | 1 |
| Bachmann, A | 1 |
| Waidelich, R | 2 |
| Rydell, R | 1 |
| Eker, C | 2 |
| Andersson-Engels, S | 2 |
| Krogdahl, A | 1 |
| Wahlberg, P | 1 |
| Svanberg, K | 2 |
| Mayinger, B | 2 |
| Neumann, F | 1 |
| Kastner, C | 1 |
| Degitz, K | 1 |
| Hahn, EG | 2 |
| Schwab, D | 1 |
| Sultan, SM | 1 |
| El-Doray, AA | 1 |
| Abdel-Gawad, O | 1 |
| El-Mahdy, Ael-D | 1 |
| Khoder, W | 1 |
| Vallinayagam, R | 1 |
| Schmitt, F | 1 |
| Barge, J | 1 |
| Wenger, V | 1 |
| Neier, R | 1 |
| Juillerat-Jeanneret, L | 1 |
| Moussa, G | 1 |
| Altmeyer, P | 1 |
| Hefti, M | 1 |
| von Campe, G | 1 |
| Moschopulos, M | 1 |
| Siegner, A | 1 |
| Looser, H | 1 |
| Landolt, H | 1 |
| Krammer, B | 1 |
| Plaetzer, K | 1 |
| Hofstädter, F | 2 |
| Tomokuni, K | 1 |
| Morita, Y | 1 |
| Araki, S | 1 |
| Sakai, T | 1 |
| Araki, T | 1 |
| Masuyama, Y | 1 |
| Steinbach, P | 2 |
| Ehsan, A | 2 |
| Lumper, W | 2 |
| Regula, J | 1 |
| Ravi, B | 1 |
| Bedwell, J | 1 |
| Bown, SG | 2 |
| Stepp, HG | 1 |
| Rick, K | 2 |
| Sterenborg, HJ | 1 |
| Saarnak, AE | 1 |
| Frank, R | 1 |
| Motamedi, M | 1 |
| Goetz, A | 1 |
| Feyh, J | 1 |
| Forrer, M | 2 |
| Mizeret, J | 2 |
| Oswald, M | 1 |
| Schmidlin, F | 2 |
| Graber, P | 2 |
| Costa, CA | 1 |
| Trivelato, GC | 1 |
| Demasi, M | 1 |
| Bechara, EJ | 1 |
| Stocker, S | 1 |
| Fritsch, C | 2 |
| Goetz, C | 1 |
| Goetz, AE | 1 |
| Kiefmann, R | 1 |
| Hornung, R | 1 |
| McHale, M | 1 |
| Sabiniano, LA | 1 |
| Tromberg, BJ | 1 |
| Berns, MW | 1 |
| Vanherzeele, H | 1 |
| Baert, L | 1 |
| Kullmann, F | 1 |
| Wild, T | 1 |
| Knüchel-Clarke, R | 1 |
| Rüschoff, J | 1 |
| Gross, V | 1 |
| Holstege, A | 1 |
| Möller, G | 1 |
| Ehrhardt, A | 1 |
| Leonhard, M | 1 |
| Petrík, R | 1 |
| Jirsa, M | 1 |
| Dvorák, E | 1 |
| Skoda, V | 1 |
| Stádník, B | 1 |
| Filbeck, T | 2 |
| Roessler, W | 2 |
| Straub, M | 2 |
| Kiel, HJ | 2 |
| Wieland, WF | 2 |
| Montán, S | 1 |
| Jaramillo, E | 1 |
| Koizumi, K | 1 |
| Rubio, C | 1 |
| Svanberg, S | 1 |
| Slezak, P | 1 |
| Schneeweiss, S | 2 |
| McGovern, FJ | 1 |
| Larne, R | 1 |
| Enquist, H | 1 |
| Deutsch, TF | 1 |
| Rogowska, AZ | 1 |
| Zenk, W | 1 |
| Dietel, W | 1 |
| Schleier, P | 1 |
| Günzel, S | 1 |
| Keller, R | 1 |
| Fischbach, W | 1 |
| Krzemien, AA | 1 |
| Van Vugt, DA | 1 |
| Pottier, RH | 2 |
| Dickson, EF | 2 |
| Reid, RL | 1 |
| Mehlmann, M | 2 |
| Arbogast, S | 3 |
| Grevers, G | 3 |
| Riedl, CR | 1 |
| Plas, E | 1 |
| Pflüger, H | 1 |
| Lord, GA | 1 |
| Luo, JL | 1 |
| Higashikawa, K | 1 |
| Furuki, K | 1 |
| Takada, S | 1 |
| Okamoto, S | 1 |
| Ukai, H | 1 |
| Yuasa, T | 1 |
| Ikeda, M | 1 |
| Weingandt, H | 1 |
| Diebold, J | 1 |
| Xiang, W | 1 |
| Cheng, CW | 1 |
| Lau, WK | 1 |
| Tan, PH | 1 |
| Bunke, A | 1 |
| Schmid, H | 1 |
| Burmeister, G | 1 |
| Merkle, HP | 1 |
| Gander, B | 1 |
| Ruzicka, T | 1 |
| Orth, K | 1 |
| Russ, D | 1 |
| Steiner, R | 1 |
| Beger, HG | 1 |
| Hauser, T | 1 |
| Szeimies, RM | 2 |
| Ackermann, G | 1 |
| Abels, C | 1 |
| Karrer, S | 1 |
| Bäumler, W | 1 |
| Landthaler, M | 1 |
| Gahlen, J | 1 |
| Pietschmann, M | 1 |
| Prosst, RL | 1 |
| Herfarth, C | 1 |
| Oberneder, R | 1 |
| De Dominicis, C | 1 |
| Liberti, M | 1 |
| Perugia, G | 1 |
| De Nunzio, C | 1 |
| Sciobica, F | 1 |
| Zuccalà, A | 1 |
| Sarkozy, A | 1 |
| Iori, F | 1 |
| Liessmann, F | 1 |
| Fischer, F | 1 |
| Wieland, H | 1 |
| Münch, P | 1 |
| Meyer, T | 1 |
| Stockfleth, E | 1 |
| Siebels, M | 1 |
| Neidhardt, S | 1 |
| Reh, H | 1 |
| Martus, P | 1 |
| Jeon, SS | 1 |
| Kang, I | 1 |
| Hong, JH | 1 |
| Choi, HY | 1 |
| Chai, SE | 1 |
| Zoepf, T | 1 |
| Jakobs, R | 1 |
| Rosenbaum, A | 1 |
| Apel, D | 1 |
| Arnold, JC | 1 |
| Riemann, JF | 1 |
| Kaneko, S | 1 |
| Pytel, A | 1 |
| Eisendrath, P | 1 |
| Van Laethem, JL | 1 |
| Lü, L | 1 |
| Lin, G | 1 |
| Xu, M | 1 |
| Zou, H | 1 |
| Wang, Q | 1 |
| Lipinski, M | 1 |
| Jeromin, L | 1 |
| Hellmig, S | 1 |
| Fölsch, UR | 1 |
| Hagimoto, H | 1 |
| Makita, N | 1 |
| Mine, Y | 1 |
| Kokubun, H | 1 |
| Murata, S | 1 |
| Abe, Y | 1 |
| Kubota, M | 1 |
| Tsutsumi, N | 1 |
| Yamasaki, T | 1 |
| Kawakita, M | 1 |
| Hori, Y | 1 |
| Mitsuyama, T | 1 |
| Miyoshi, H | 1 |
| Shimatani, M | 1 |
| Uchida, K | 1 |
| Takaoka, M | 1 |
| Kamiya, A | 1 |
| Okazaki, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Computer Based Algorithm for Patient Specific Implants for Cranioplasty in Patients With Skull Defects: a Prospective Clinical Trial[NCT02828306] | 15 participants (Actual) | Observational | 2016-09-30 | Completed | |||
| 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas[NCT05850377] | 90 participants (Anticipated) | Observational | 2023-06-01 | Not yet recruiting | |||
| Fractional Carbon Dioxide Laser Assisted Delivery of Topical Anesthetics: a Randomized Controlled Pilot Study[NCT02246179] | Phase 4 | 10 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| A Randomized Half-side Comparative Trial of Fractional Laser-assisted Daylight Photodynamic Therapy Versus Daylight Photodynamic Therapy in Organ Transplant Recipients With Multiple Actinic Keratoses of the Scalp or Forehead[NCT01898936] | 12 participants (Actual) | Interventional | 2013-08-31 | Completed | |||
| Parameters in Fractional Laser Assisted Delivery of Topical Anesthetics: Role of Anesthetic and Application Time[NCT03279757] | Phase 4 | 15 participants (Actual) | Interventional | 2016-10-01 | Completed | ||
| Open Label Prospective Trial of Fractional Ablative CO 2 Resurfacing With Laser- Facilitated Steroid Delivery in Patients With Mild to Moderate Hidradenitis Suppurativa.[NCT05580029] | Early Phase 1 | 10 participants (Anticipated) | Interventional | 2022-11-01 | Not yet recruiting | ||
| Parameters in Fractional Laser Assisted Delivery of Topical Anesthetics: Role of Laser Type and Laser Settings[NCT02938286] | Phase 4 | 15 participants (Actual) | Interventional | 2016-03-31 | Completed | ||
| Fractional CO2 Laser Assisted Topical Articaine Anesthesia vs. Topical EMLA Administration: a Randomized Controlled Study[NCT02548533] | Phase 4 | 3 participants (Actual) | Interventional | 2015-06-30 | Terminated (stopped due to Not enough patients eligible for recruitment.) | ||
| The Correlation of Surgical Colorectal Cancer Specimen Pathology With the Fluorescence of Photodynamic Diagnostics (PDD): a Clinical Pilot Study[NCT03272659] | Phase 2 | 0 participants (Actual) | Interventional | 2018-04-01 | Withdrawn (stopped due to Long process and due to strict deadline, project was stopped.) | ||
| [NCT01344902] | Phase 1/Phase 2 | 13 participants (Actual) | Interventional | 2009-02-28 | Terminated (stopped due to The study was stopped due to inadequate efficacy after 13 patients were evaluated.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 reviews available for aminolevulinic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
Recent advances in optical imaging technologies for the detection of bladder cancer.
Topics: Aminolevulinic Acid; Cystoscopy; Humans; Microscopy, Confocal; Molecular Imaging; Photosensitizing A | 2018 |
Hexaminolevulinate in the Management of Nonmuscle Invasive Bladder Cancer: A Meta-Analysis.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Humans; Neoplasm Invasiveness; Photosensitizing | 2019 |
Intraoperative fluorescence-guided resection of high-grade malignant gliomas using 5-aminolevulinic acid-induced porphyrins: a systematic review and meta-analysis of prospective studies.
Topics: Aminolevulinic Acid; Brain Neoplasms; Clinical Trials as Topic; Fluorescence; Glioma; Humans; Intrao | 2013 |
Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; False Negative Rea | 2013 |
5-Aminolevulinic acid-based fluorescence diagnostics of cervical preinvasive changes.
Topics: Aminolevulinic Acid; Female; Fluorescence; Humans; Photosensitizing Agents; Protoporphyrins; Sensiti | 2014 |
5-Aminolevulinic Acid-Protoporphyrin IX Fluorescence-Guided Surgery of High-Grade Gliomas: A Systematic Review.
Topics: Aminolevulinic Acid; Brain; Brain Neoplasms; Fluorescence; Glioblastoma; Humans; Microscopy, Fluores | 2016 |
[Diagnosis of the porphyrias : From A (as in aminolevulinic acid) to Z (as in zinc protoporphyrin)].
Topics: Aminolevulinic Acid; Biomarkers; Diagnosis, Differential; Porphyrias; Protoporphyrins; Reproducibili | 2016 |
ALA-induced fluorescence image guided surgery of meningiomas: A meta-analyses.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Contrast Media; Female; Fluorescent Dyes; Humans; Male | 2016 |
Hexyl aminolevulinate fluorescence cystoscopy in bladder cancer.
Topics: Aminolevulinic Acid; Clinical Trials as Topic; Cystoscopy; Fluorescent Dyes; Humans; Neoplasm Recurr | 2009 |
[Fluorescence diagnosis in patients with non-muscle invasive bladder cancer: results of a metaanalysis].
Topics: Aminolevulinic Acid; Cystoscopy; Disease-Free Survival; Fluorescence; Humans; Neoplasm Invasiveness; | 2010 |
Value of fluorescence endoscopy for the early diagnosis of laryngeal cancer and its precursor lesions.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Early Detection of Cancer; Endoscopy; Fluorescence; H | 2011 |
Fluorescence detection of bladder cancer: a review.
Topics: Administration, Intravesical; Aminolevulinic Acid; Anthracenes; Carcinoma in Situ; Cystoscopy; Dihem | 2002 |
[Fluorescence imaging technique: diagnostic and therapeutic interest in gynecology].
Topics: Aminolevulinic Acid; Breast Neoplasms; Female; Genital Diseases, Female; Gynecology; Humans; Neoplas | 2004 |
Recent developments in fluorescence cystoscopy: do novel agents bring a benefit?
Topics: Aminolevulinic Acid; Anthracenes; Carcinoma in Situ; Cystoscopy; Fluorescence; Fluorescent Dyes; Hum | 2007 |
[Fluorescence cystoscopy at bladder cancer: present trials].
Topics: Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Fluorescen | 2007 |
["... The better to see you with"--phothodynamic diagnostic in superficial bladder cancer].
Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Carcinoma in Situ; Carcinoma, Papillary; | 2007 |
[Fluorescence diagnosis and photodynamic therapy in urology].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II | 2007 |
ALA and its clinical impact, from bench to bedside.
Topics: Aminolevulinic Acid; Dendritic Cells; Fluorescence; Humans; Keratosis; Lymphocytes; Macrophages; Neo | 2008 |
[Delta-Aminolevulinic acid in urine (screening method)].
Topics: Aminolevulinic Acid; Chromatography, High Pressure Liquid; Colorimetry; Fluorometry; Humans; Porphyr | 1995 |
New photosensitizers for photodynamic therapy in gastroenterology.
Topics: Aminolevulinic Acid; Female; Gastrointestinal Diseases; Humans; Male; Organophosphorus Compounds; Ph | 1999 |
[Intraoperative photodynamic diagnosis of human glioma using ALA induced protoporphyrin IX].
Topics: Aminolevulinic Acid; Animals; Brain Neoplasms; Glioma; Humans; Male; Mice; Middle Aged; Monitoring, | 2001 |
35 trials available for aminolevulinic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; F | 2018 |
Oral 5-aminolevulinic acid induced Photodynamic Diagnostic Ureterorenoscopy--does the blood pressure require monitoring?
Topics: Administration, Oral; Aged; Aminolevulinic Acid; Blood Pressure; Contrast Media; Female; Humans; Hyp | 2013 |
Comparison of efficiency of photodynamic diagnostics with topical use of the 3% and 15% aminolevulinic acid in the detection of vulvar lesions.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Dose-Response Relationship, Drug; Female; | 2013 |
Porphyrins as urinary biomarkers for bladder cancer after 5-aminolevulinic acid (ALA) administration: the potential of photodynamic screening for tumors.
Topics: Adult; Aged; Aminolevulinic Acid; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Early Det | 2013 |
Impact of 5-aminolevulinic acid fluorescence-guided surgery on the extent of resection of meningiomas--with special regard to high-grade tumors.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Contrast Media; Female; Fluorescent Dyes; Human | 2014 |
Does fluorescence diagnosis have a role in follow up of response to therapy in mycosis fungoides?
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Contrast Media; Dermoscopy; Female; Follow-Up Studies; | 2014 |
Oral 5-aminolevulinic acid mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A randomized, double-blind, multicentre phase II/III study.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Dose-Response Relationship, Drug; D | 2015 |
Performance of 5-aminolevulinic-acid-based photodynamic diagnosis for radical prostatectomy.
Topics: Aged; Aminolevulinic Acid; Contrast Media; Humans; Image Enhancement; Laparoscopy; Male; Microscopy, | 2015 |
Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study.
Topics: Adult; Aged; Aminolevulinic Acid; Dose-Response Relationship, Drug; Drug Administration Schedule; Fe | 2017 |
Plasma porphobilinogen as a sensitive biomarker to monitor the clinical and therapeutic course of acute intermittent porphyria attacks.
Topics: Acute Disease; Adult; Aminolevulinic Acid; Arginine; Biomarkers; Chromatography, Ion Exchange; Drug | 2009 |
Intraoperative optical identification of pituitary adenomas.
Topics: Adenoma; Aminolevulinic Acid; Diagnostic Imaging; False Negative Reactions; False Positive Reactions | 2009 |
Fluorescence cystoscopy with high-resolution optical coherence tomography imaging as an adjunct reduces false-positive findings in the diagnosis of urothelial carcinoma of the bladder.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; False Positive Reactions; Female; F | 2009 |
Which intracranial lesions would be suitable for 5-aminolevulenic acid-induced fluorescence-guided identification, localization, or resection? A prospective study of 114 consecutive intracranial lesions.
Topics: Aminolevulinic Acid; Brain Neoplasms; Follow-Up Studies; Humans; Photosensitizing Agents; Prospectiv | 2009 |
Treatment changes and long-term recurrence rates after hexaminolevulinate (HAL) fluorescence cystoscopy: does it really make a difference in patients with non-muscle-invasive bladder cancer (NMIBC)?
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Contrast Media; Cystoscopy; Disease Progression | 2012 |
PpIX fluorescence combined with auto-fluorescence is more accurate than PpIX fluorescence alone in fluorescence detection of non-melanoma skin cancer: an intra-patient direct comparison study.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Bowen's Disease; Carcinoma; Carcinoma, Basal Cell; False Neg | 2012 |
Hexyl aminolevulinate fluorescence cystoscopy: new diagnostic tool for photodiagnosis of superficial bladder cancer--a multicenter study.
Topics: Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Humans; Male; Middle Aged; Neoplas | 2003 |
Reduced specificity of 5-ALA induced fluorescence in photodynamic diagnosis of transitional cell carcinoma after previous intravesical therapy.
Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Transitional | 2003 |
Fluorescence-guided resections of malignant gliomas--an overview.
Topics: Aminolevulinic Acid; Biopsy; Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Division; Fluorescenc | 2003 |
Photodynamic detection of diseased axillary sentinel lymph node after oral application of aminolevulinic acid in patients with breast cancer.
Topics: Administration, Oral; Adult; Aminolevulinic Acid; Axilla; Breast Neoplasms; Female; Humans; Light; L | 2004 |
Laparoscopic fluorescence detection of ovarian carcinoma metastases using 5-aminolevulinic acid-induced protoporphyrin IX.
Topics: Adult; Aged; Aminolevulinic Acid; Female; Fluorescence; Humans; Infusions, Parenteral; Laparoscopy; | 2004 |
[The impact of ALA (5-aminolevulinic acid)-fluorescence detection on the prognosis of superficial bladder cancer].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Fluorescence; Follow-Up Stu | 2004 |
Improved detection and treatment of bladder cancer using hexaminolevulinate imaging: a prospective, phase III multicenter study.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Cystoscop | 2005 |
Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Humans; Middle Aged; Mouth Neoplasms; P | 2006 |
In-vivo kinetics of inhaled 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in bronchial tissue.
Topics: Administration, Inhalation; Aged; Aged, 80 and over; Aminolevulinic Acid; Bronchi; Bronchial Neoplas | 2007 |
Photodynamic selectivity of 5-aminolevulinic acid to prostate cancer cells.
Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Biological Availability; Combined Modality Therapy; Human | 2006 |
Fluorescence photodetection of neoplastic urothelial lesions following intravesical instillation of 5-aminolevulinic acid.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Femal | 1994 |
Is everything all right if nothing seems wrong? A simple method of assessing the diagnostic value of endoscopic procedures when a gold standard is absent.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Humans; Male; M | 1999 |
Photodynamic cystoscopy for detection of bladder tumors.
Topics: Adenocarcinoma, Papillary; Administration, Intravesical; Aminolevulinic Acid; Biopsy; Cystoscopy; Di | 1999 |
Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy.
Topics: Adenocarcinoma, Papillary; Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinom | 1999 |
Fluorescence detection of bladder tumors with 5-amino-levulinic acid.
Topics: Adult; Aged; Aminolevulinic Acid; Cystoscopy; Fluorescence; Humans; Middle Aged; Photosensitizing Ag | 1999 |
Photodetection of cervical intraepithelial neoplasia using 5-aminolevulinic acid-induced porphyrin fluorescence.
Topics: Adult; Aminolevulinic Acid; Female; Humans; Photosensitizing Agents; Porphyrins; Sensitivity and Spe | 2000 |
Cystoscopic diagnosis of bladder cancer by intravesical instillation of 5-aminolevulinic acid induced porphyrin fluorescence--the Singapore experience.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy, Needle; C | 2000 |
Endoscopic detection of transitional cell carcinoma with 5-aminolevulinic acid: results of 1012 fluorescence endoscopies.
Topics: Administration, Intravesical; Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biops | 2001 |
Fluorescence urethroscopy following instillation of 5-aminolevulinic acid: a new procedure for detecting clinical and subclinical HPV lesions of the urethra.
Topics: Adolescent; Adult; Aminolevulinic Acid; Biopsy, Needle; Condylomata Acuminata; DNA, Viral; Endoscopy | 2001 |
Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluoresc | 2001 |
155 other studies available for aminolevulinic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
5-ALA-mediated fluorescence of musculoskeletal tumors in a chick chorio-allantoic membrane model: preclinical in vivo qualification analysis as a fluorescence-guided surgery agent in Orthopedic Oncology.
Topics: Allantois; Aminolevulinic Acid; Animals; Chick Embryo; Contrast Media; Fluorescence; Fluorescent Dye | 2022 |
Significance of in vitro photodynamic cytodiagnosis with 5-aminolevulinic acid in biliary brush cytology for malignant biliary stricture.
Topics: Aminolevulinic Acid; Bile Duct Neoplasms; Cholestasis; Constriction, Pathologic; Cytodiagnosis; Huma | 2022 |
Significance of in vitro photodynamic cytodiagnosis using 5-aminolevulinic acid in solid pancreatic tumors extracted by endoscopic ultrasound-guided fine-needle aspiration.
Topics: Aged; Aminolevulinic Acid; Endoscopic Ultrasound-Guided Fine Needle Aspiration; Humans; Male; Pancre | 2021 |
5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence ureterorenoscopy for urinary upper tract urothelial carcinoma ∼Preliminary prospective single centre trial∼.
Topics: Administration, Oral; Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluorescence | 2020 |
Evaluation of autofluorescence and photodynamic diagnosis in assessment of bladder lesions.
Topics: Aminolevulinic Acid; Cystectomy; Cystoscopy; Humans; Photochemotherapy; Photosensitizing Agents; Sen | 2020 |
Plasma enabled devices for the selective capture and photodynamic identification of prostate cancer cells.
Topics: Aminolevulinic Acid; Cell Count; Cell Line, Tumor; Cell Nucleus; Fluorescence; Humans; Male; Microfl | 2020 |
Improving hexaminolevulinate enabled cancer cell detection in liquid biopsy immunosensors.
Topics: Aminolevulinic Acid; Biosensing Techniques; Cell Line, Tumor; Cells, Cultured; Humans; Immunologic T | 2021 |
Blue light cystoscopy with hexylaminolevulinate: Our 7 years experience.
Topics: Aged; Aminolevulinic Acid; Biopsy; Cystoscopy; Female; Humans; Light; Male; Predictive Value of Test | 2017 |
Pathological analysis of the surgical margins of resected glioblastomas excised using photodynamic visualization with both 5-aminolevulinic acid and fluorescein sodium.
Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Female; Fluorescein; Glioblastoma; Humans; Ki-67 | 2017 |
Fluorescence Behavior and Dural Infiltration of Meningioma Analyzed by 5-Aminolevulinic Acid-Based Fluorescence: Operating Microscope Versus Mini-Spectrometer.
Topics: Aminolevulinic Acid; Calibration; Dura Mater; Fluorescent Dyes; Humans; Magnetic Resonance Imaging; | 2017 |
Diagnostic accuracy of intraoperative perfusion-weighted MRI and 5-aminolevulinic acid in relation to contrast-enhanced intraoperative MRI and
Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Female; Gadolinium DTPA; Glioblastoma; Humans; Ma | 2019 |
High diagnostic efficacy of 5-aminolevulinic acid-induced fluorescent urine cytology for urothelial carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cytodiagnosis; Female; Fluorescence; Humans; Ma | 2019 |
[Bladder tumor targeting by Hexvix(®) fluorescence: 4 years results after prospective monocentric evaluation].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Fluorescence; France; Human | 2013 |
Improvement of aminolevulinic acid (ALA)-mediated photodynamic diagnosis using n-propyl gallate.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Drug Combinations; Drug Synergism; Humans; Image Enhancement; | 2013 |
5-Aminolevulinic acid-induced protoporphyrin IX fluorescence in meningioma: qualitative and quantitative measurements in vivo.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Analysis of Variance; Cluster Analysis; Female; | 2014 |
5-Aminolevulinic acid induced fluorescence is a powerful intraoperative marker for precise histopathological grading of gliomas with non-significant contrast-enhancement.
Topics: Adult; Aged; Aminolevulinic Acid; Biomarkers; Brain; Brain Neoplasms; Female; Fluorescence; Glioma; | 2013 |
Photodynamic diagnosis using 5-aminolevulinic acid during gastrectomy for gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Feasibility Studies; Female; Fluorescence; Gast | 2014 |
Optimizing the antitumor selectivity of PVP-Hypericin re A549 cancer cells and HLF normal cells through pulsed blue light.
Topics: Aminolevulinic Acid; Anthracenes; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Color; Dose-Re | 2013 |
Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meni | 2014 |
Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meni | 2014 |
Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meni | 2014 |
Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meni | 2014 |
Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cell Line, Tumor; Cytologica | 2014 |
Survey of aflatoxins in rice from Iran using immunoaffinity column clean-up and HPLC with fluorescence detection.
Topics: Aflatoxin B1; Aflatoxins; Aminolevulinic Acid; Chromatography, Affinity; Chromatography, High Pressu | 2010 |
Malignant glioma: MR imaging by using 5-aminolevulinic acid in an animal model.
Topics: Aminolevulinic Acid; Animals; Brain Neoplasms; Cell Line, Tumor; Contrast Media; Disease Models, Ani | 2014 |
Identification of skin lesions through aminolaevulinic acid-mediated photodynamic detection.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Contrast Media; Dermoscopy; Equipment Design; Eq | 2014 |
Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Biomarkers, Tumor; Feasibility Studies; Humans; Male; | 2014 |
Effectiveness of hexaminolevulinate fluorescence cystoscopy for the diagnosis of non-muscle-invasive bladder cancer in daily clinical practice: a Spanish multicentre observational study.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Humans; Male; Middle Aged; | 2015 |
Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cell Line, Tumor; Female; Humans; Male; Middle | 2015 |
[Cost-effectiveness of transurethral resection of the bladder with blue light in patients with non muscle invasive bladder cancer in France].
Topics: Administration, Intravesical; Aged; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cost Savings; | 2015 |
5-Aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett's esophagus cellular models.
Topics: Adenocarcinoma; Algorithms; Aminolevulinic Acid; Barrett Esophagus; Biomarkers; Esophageal Neoplasms | 2015 |
The effect of iron ion on the specificity of photodynamic therapy with 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Cation Transport Proteins; Cell Line, Tumor; Heme; Humans; Iron; MCF-7 Cells; M | 2015 |
In vivo fluorescence navigation of gastric and upper gastrointestinal tumors by 5-aminolevulinic acid mediated photodynamic diagnosis with a laser-equipped video image endoscope.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Signet Ring Cell; En | 2015 |
5-aminolevulinic-acid-based fluorescence spectroscopy and conventional colposcopy for in vivo detection of cervical pre-malignancy.
Topics: Adult; Aminolevulinic Acid; Colposcopy; Early Detection of Cancer; Female; Humans; Middle Aged; Phot | 2015 |
Photodynamic diagnostic ureterorenoscopy: A valuable tool in the detection of upper urinary tract tumour.
Topics: Administration, Oral; Aminolevulinic Acid; Image Enhancement; Kidney Neoplasms; Photosensitizing Age | 2016 |
Intraoperative Detection of Superficial Liver Tumors by Fluorescence Imaging Using Indocyanine Green and 5-aminolevulinic Acid.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Diagnostic Imaging; Female; Fluorescence; Fluorescent | 2016 |
Prediction of genetic subgroups in adult supra tentorial gliomas by pre- and intraoperative parameters.
Topics: Adult; Aminolevulinic Acid; Female; Glioma; Humans; Isocitrate Dehydrogenase; Magnetic Resonance Spe | 2017 |
Diagnostic Accuracy of Hexaminolevulinate in a Cohort of Patients Undergoing Radical Cystectomy.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell | 2017 |
Histopathological Insights on Imaging Results of Intraoperative Magnetic Resonance Imaging, 5-Aminolevulinic Acid, and Intraoperative Ultrasound in Glioblastoma Surgery.
Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Female; Glioblastoma; Humans; Magnetic Resonance | 2017 |
Quantitative determination of 5-aminolaevulinic acid and its esters in cell lysates by HPLC-fluorescence.
Topics: Aminolevulinic Acid; Analysis of Variance; Animals; Cell Line; Chromatography, High Pressure Liquid; | 2008 |
Preoperative assessment of basal cell carcinoma using conventional fluorescence diagnosis.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Diagnostic Imaging; Female; Flu | 2009 |
Hexylaminolaevulinate 'blue light' fluorescence cystoscopy in the investigation of clinically unconfirmed positive urine cytology.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell | 2009 |
Nondestructive testing in urologic oncology.
Topics: Aminolevulinic Acid; Forecasting; Humans; Male; Medical Oncology; Microscopy, Fluorescence; Prostate | 2009 |
Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region.
Topics: Adult; Aminolevulinic Acid; Condylomata Acuminata; Dermoscopy; Female; Humans; Image Enhancement; Ma | 2008 |
Raman spectroscopy of bladder tissue in the presence of 5-aminolevulinic acid.
Topics: Algorithms; Aminolevulinic Acid; Diagnosis, Differential; Discriminant Analysis; Early Detection of | 2009 |
Blue-sky thinking about blue-light cystoscopy.
Topics: Aminolevulinic Acid; Cystoscopy; Humans; Microscopy, Fluorescence; Neoplasm Recurrence, Local; Photo | 2009 |
Photodynamic diagnosis (5-aminolevulinic acid) of transitional cell carcinoma after bacillus Calmette-Guérin immunotherapy and mitomycin C intravesical therapy.
Topics: Administration, Intravesical; Aminolevulinic Acid; Antibiotics, Antineoplastic; BCG Vaccine; Biopsy; | 2010 |
[Comparison of sensitivity and specificity of PDD, colposcopy and cytology in the detection of cervical neoplastic lesions].
Topics: Adult; Aminolevulinic Acid; Cervix Uteri; Colposcopy; Cytological Techniques; Female; Fluorescence; | 2009 |
[Clinical experience with transurethral resection of bladder tumor (TUR-Bt) guided by photodynamic diagnosis (PDD)].
Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Disease-Free Survival; F | 2009 |
Signal-to-noise contribution of principal component loads in reconstructed near-infrared Raman tissue spectra.
Topics: Administration, Intravesical; Algorithms; Aminolevulinic Acid; Biopsy; Cystitis; Cystoscopy; Discrim | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
Fractional CO(2) laser-assisted drug delivery.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Delivery Systems; Lasers, Gas; Low-Lev | 2010 |
[Fluorescence diagnostics of skin tumors using 5-aminolevulinic acid and its methyl ester].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell | 2009 |
Enhancement of blood porphyrin emission intensity with aminolevulinic acid administration: a new concept for photodynamic diagnosis of early prostate cancer.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Cell Line, Tumor; Drug Synergism; Drug Therapy, | 2011 |
5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor.
Topics: Aminolevulinic Acid; Animals; Carcinoma; Cell Line, Tumor; Fluorescence; Humans; Lung Neoplasms; Mes | 2011 |
Intraoperative photodynamic detection of normal parathyroid glands using 5-aminolevulinic acid.
Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Female; Fluorescence; Humans; Hyperthyroidis | 2011 |
Direct UPLC-MS-MS validated method for the quantification of 5-aminolevulinic acid: application to in-vitro assessment of colonic-targeted oral tablets.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Chromatography, High Pressure Liquid; Colon; Dru | 2011 |
Comparison between intravesical and oral administration of 5-aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer.
Topics: Administration, Intravesical; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic A | 2012 |
A LC-MS/MS method for the specific, sensitive, and simultaneous quantification of 5-aminolevulinic acid and porphobilinogen.
Topics: Adolescent; Adult; Aminolevulinic Acid; Animals; Child; Child, Preschool; Chromatography, Liquid; Di | 2011 |
δ-aminolevulinic acid-induced protoporphyrin IX concentration correlates with histopathologic markers of malignancy in human gliomas: the need for quantitative fluorescence-guided resection to identify regions of increasing malignancy.
Topics: Adult; Aged; Aminolevulinic Acid; Biomarkers; Brain Neoplasms; Diagnostic Imaging; Female; Fluoresce | 2011 |
Combined fluorescence and reflectance spectroscopy for in vivo quantification of cancer biomarkers in low- and high-grade glioma surgery.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Diagnostic Imaging; Glioma; Humans; Models, Biological; Prot | 2011 |
Porphyrins in urine after administration of 5-aminolevulinic acid as a potential tumor marker.
Topics: Aminolevulinic Acid; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Mice; | 2011 |
Intraoperative tissue fluorescence using 5-aminolevolinic acid (5-ALA) is more sensitive than contrast MRI or amino acid positron emission tomography ((18)F-FET PET) in glioblastoma surgery.
Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Contrast Media; Female; Fluorescent Dyes; Gliobla | 2012 |
Evaluation of unbound free heme in plant cells by differential acetone extraction.
Topics: Acetone; Acids; Aminolevulinic Acid; Animals; Arabidopsis; Arabidopsis Proteins; Cell Nucleus; Chemi | 2012 |
Direct and simultaneous determination of 5-aminolaevulinic acid and porphobilinogen in urine by hydrophilic interaction liquid chromatography-electrospray ionisation/tandem mass spectrometry.
Topics: Aminolevulinic Acid; Analysis of Variance; Chromatography, Liquid; Humans; Hydrophobic and Hydrophil | 2012 |
Reflectance confocal microscopy allows in vivo real-time noninvasive assessment of the outcome of methyl aminolaevulinate photodynamic therapy of basal cell carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Dermoscopy; Female; Foll | 2013 |
Direct and simultaneous quantitation of 5-aminolaevulinic acid and porphobilinogen in human serum or plasma by hydrophilic interaction liquid chromatography-atmospheric pressure chemical ionization/tandem mass spectrometry.
Topics: Aminolevulinic Acid; Chromatography, Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Least | 2013 |
[Fluorescence cystoscopy in bladder cancer: what future?].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Diagnosis, Differe | 2002 |
Role of 5-aminolevulinic acid in the detection of urothelial premalignant lesions.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; End | 2002 |
Detection of squamous cell carcinomas and pre-cancerous lesions in the oral cavity by quantification of 5-aminolevulinic acid induced fluorescence endoscopic images.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Aminolevulinic Acid; Carcinoma, Squamous Cell; Diagnosti | 2002 |
Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor.
Topics: Aminolevulinic Acid; Analysis of Variance; Bronchi; Bronchial Neoplasms; Carcinoma, Non-Small-Cell L | 2002 |
Detection of high-grade dysplasia in Barrett's esophagus by spectroscopy measurement of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esopha | 2002 |
Molecular and biochemical studies of acute intermittent porphyria in 196 patients and their families.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; DNA; Family; Feces; Female; Humans; Hydroxymethylbilan | 2002 |
[Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid].
Topics: Administration, Inhalation; Administration, Oral; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous C | 2002 |
Laparoscopic photodynamic diagnosis of ovarian cancer using 5-aminolevulinic acid in a rat model.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Female; Fluorescence; Laparoscopy; Neoplasm Metastasis | 2002 |
Acceleration of ALA-induced PpIX fluorescence development in the oral mucosa.
Topics: Administration, Topical; Aminolevulinic Acid; Analysis of Variance; Animals; Carcinoma, Squamous Cel | 2003 |
Fluorescence cytology of the urinary bladder.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Trans | 2003 |
Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study.
Topics: Aminolevulinic Acid; Animals; Diagnostic Techniques and Procedures; Disease Models, Animal; Drug Eva | 2003 |
Fluorescence endoscopy for the detection of low and high grade dysplasia in ulcerative colitis using systemic or local 5-aminolaevulinic acid sensitisation.
Topics: Adult; Aged; Aminolevulinic Acid; Biopsy; Colitis, Ulcerative; Endoscopy, Gastrointestinal; Feasibil | 2003 |
Measurement of urinary porphyrins and porphyrin precursors in Dutch hospital laboratories: a review of quality control over 5 years.
Topics: Aminolevulinic Acid; Clinical Chemistry Tests; Coproporphyrins; Humans; Laboratories, Hospital; Neth | 2003 |
ALA (5-aminolevulinic acid)-induced protoporphyrin IX fluorescence in the endoscopic diagnostic and control of pharyngo-laryngeal cancer.
Topics: Adult; Aged; Aminolevulinic Acid; Diagnosis, Differential; Female; Fluorescence; Humans; Laryngeal N | 2004 |
[Photodynamic diagnosis of vulvar precancerous conditions and invasive cancers using 5-aminolevulinic acid].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Diagnostic Techniques, Obstetrical and Gynecological; Female | 2003 |
The light at the end of the tunnel.
Topics: Administration, Oral; Aminolevulinic Acid; Colitis, Ulcerative; Colonoscopy; Enema; Female; Fluoresc | 2003 |
Detection of dysplastic lesions by fluorescence in a model of chronic colitis in rats after local application of 5-aminolevulinic acid and its esterified derivatives.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Biopsy; Chronic Disease; Colitis; Colon; Dise | 2004 |
The use of digitized endoscopic imaging of 5-ALA-induced PPIX fluorescence to detect and diagnose oral premalignant and malignant lesions in vivo.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Diagnostic Imaging; Endoscopy; Female; Fluoresc | 2004 |
The photodynamic diagnosis (PDD) for early detection of carcinoma and dysplasia of the bladder.
Topics: Aminolevulinic Acid; Biopsy; Carcinoma, Transitional Cell; Cystoscopy; Early Diagnosis; Fluorescence | 2003 |
Detection of cytochrome C in a single cell using an optical nanobiosensor.
Topics: Aminolevulinic Acid; Apoptosis; Biosensing Techniques; Cell Line, Tumor; Cytochromes c; Enzyme Activ | 2004 |
Detection of nonpigmented endometriotic lesions with 5-aminolevulinic acid-induced fluorescence.
Topics: Adult; Aminolevulinic Acid; Endometriosis; Female; Fluorescence; Humans; Laparoscopy; Photosensitizi | 2004 |
Diagnostic value of the PDD method in evaluation of vulvar lesions.
Topics: Adult; Aged; Aminolevulinic Acid; Female; Humans; Microscopy; Middle Aged; Photochemotherapy; Photos | 2005 |
[Value of the photodynamic method in the diagnosis of superficial bladder tumors].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cystoscopy; Early | 2004 |
Stability of 5-aminolevulinic acid on dried urine filter paper for a diagnostic marker of tyrosinemia type I.
Topics: Aminolevulinic Acid; Biomarkers; Filtration; Gas Chromatography-Mass Spectrometry; Humans; Reproduci | 2005 |
Synthesis of 5-aminolevulinic acid (ALA) and its t-butyl ester for the fluorescence detection of early cancer.
Topics: Aminolevulinic Acid; Early Diagnosis; Fluorescence; Humans; Neoplasms; Sensitivity and Specificity | 2005 |
The temperature dependence of porphyrin production in Propionibacterium acnes after incubation with 5-aminolevulinic acid (ALA) and its methyl ester (m-ALA).
Topics: Aminolevulinic Acid; Light; Photosensitizing Agents; Porphyrins; Propionibacterium acnes; Sensitivit | 2006 |
Photobleaching kinetics, photoproduct formation, and dose estimation during ALA induced PpIX PDT of MLL cells under well oxygenated and hypoxic conditions.
Topics: Aminolevulinic Acid; Animals; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Dose-Response Relations | 2006 |
Fluorescence staining of human ovarian cancer tissue following application of 5-aminolevulinic acid: fluorescence microscopy studies.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Biopsy; Fallopian Tube Neoplasms; Female; Humans; Laparoscop | 2006 |
Possibility of using laser spectroscopy for the intraoperative detection of nonfluorescing brain tumors and the boundaries of brain tumor infiltrates. Technical note.
Topics: Adult; Aminolevulinic Acid; Astrocytoma; Brain; Brain Neoplasms; Female; Humans; Lasers; Male; Middl | 2006 |
Integral spectrophotometric analysis of 5-aminolaevulinic acid-induced fluorescence cytology of the urinary bladder.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Transitional Cell; Female; Humans; M | 2006 |
Detection of peritoneal endometriotic lesions by autofluorescence laparoscopy.
Topics: Adult; Aminolevulinic Acid; Endometriosis; Female; Fluorescence; Humans; Laparoscopy; Peritoneal Dis | 2006 |
The effect of folic acid on porphyrin synthesis in tumors and normal skin of mice treated with 5-aminolevulinic acid or methyl 5-aminolevulinate.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Colonic Neoplasms; Female; Folic Acid; Humans; Injecti | 2006 |
[Intraoperative photodynamic diagnosis for spinal ependymoma using 5-aminolevulinic acid: technical note].
Topics: Adult; Aminolevulinic Acid; Ependymoma; Female; Fluorescence; Humans; Intraoperative Period; Lightin | 2006 |
Relation between intracellular location and photodynamic efficacy of 5-aminolevulinic acid-induced protoporphyrin IX in vitro. Comparison between human glioblastoma cells and other cancer cell lines.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Dose-Response Relationship | 2007 |
Seven years' experience with 5-aminolevulinic acid in detection of transitional cell carcinoma of the bladder.
Topics: Administration, Intravesical; Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carci | 2007 |
Detection of urinary bladder cancer with flow cytometry and hexaminolevulinate in urine samples.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cell | 2007 |
Photodetection of basal cell carcinoma using methyl 5-aminolaevulinate-induced protoporphyrin IX based on fluorescence image analysis.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Facial Neoplasms; Female; Humans; Male; Middle Age | 2007 |
[Photodynamic diagnostic of superficial bladder carcinoma].
Topics: Administration, Intravesical; Aminolevulinic Acid; Germany; Humans; Length of Stay; Photosensitizing | 2007 |
Fluorescence investigations to classify malignant laryngeal lesions in vivo.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma; Female; Humans; Laryngeal Ne | 2008 |
Early detection of premalignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate.
Topics: Aged; Aminolevulinic Acid; Biopsy, Needle; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Early Dia | 2008 |
Early detection of premalignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate.
Topics: Aged; Aminolevulinic Acid; Biopsy, Needle; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Early Dia | 2008 |
Early detection of premalignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate.
Topics: Aged; Aminolevulinic Acid; Biopsy, Needle; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Early Dia | 2008 |
Early detection of premalignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate.
Topics: Aged; Aminolevulinic Acid; Biopsy, Needle; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Early Dia | 2008 |
Glycoside esters of 5-aminolevulinic acid for photodynamic therapy of cancer.
Topics: Aminolevulinic Acid; Cell Line; Cell Line, Tumor; Cell Proliferation; Endothelial Cells; Esterases; | 2008 |
A pilot study of fluorescence diagnosis of basal cell carcinoma using a digital flash light-based imaging system.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Diagnostic Imaging; Female; Flu | 2008 |
5-aminolevulinic acid induced protoporphyrin IX fluorescence in high-grade glioma surgery: a one-year experience at a single institutuion.
Topics: Aminolevulinic Acid; Biopsy; Fluorescence; Glioma; Humans; Prognosis; Protoporphyrins; Sensitivity a | 2008 |
Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence.
Topics: Administration, Intravesical; Aged; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Carcinoma, Trans | 1996 |
Determination of delta-aminolevulinic acid in plasma using high-performance liquid chromatography: a sensitive indicator of lead effects.
Topics: Adult; Aminolevulinic Acid; Chromatography, High Pressure Liquid; Environmental Monitoring; Fluorome | 1994 |
Photodynamic therapy using 5-aminolaevulinic acid for experimental pancreatic cancer--prolonged animal survival.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Cricetinae; Disease Models, Animal; Female; Heme | 1994 |
Fluorescence cystoscopy following intravesical instillation of 5-aminolevulinic acid: a new procedure with high sensitivity for detection of hardly visible urothelial neoplasias.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Epith | 1995 |
Evaluation of spectral correction techniques for fluorescence measurements on pigmented lesions in vivo.
Topics: Adult; Aminolevulinic Acid; Humans; Male; Melanoma; Sensitivity and Specificity; Spectrometry, Fluor | 1996 |
[Photodynamic diagnosis of neoplasms of the mouth cavity after local administration of 5-aminolevulinic acid].
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Fluorescence; | 1996 |
Clinical assessment of fluorescence cytoscopy during transurethral bladder resection in superficial bladder cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cystoscopes; Cyst | 1997 |
[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder].
Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carci | 1997 |
Determination of 5-aminolevulinic acid in blood plasma, tissues and cell cultures by high-performance liquid chromatography with electrochemical detection.
Topics: Air Pollutants, Occupational; Aminolevulinic Acid; Animals; Brain; Cells, Cultured; CHO Cells; Chrom | 1997 |
Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence.
Topics: Aged; Aminolevulinic Acid; Brain Neoplasms; Female; Fluorescence; Fluorometry; Glioma; Humans; Intra | 1998 |
In vivo detection of metastatic ovarian cancer by means of 5-aminolevulinic acid-induced fluorescence in a rat model.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Female; Fluorescence; Injections, Intravenous; | 1998 |
Fluorescence detection of flat transitional cell carcinoma after intravesical instillation of aminolevulinic acid.
Topics: Administration, Intravesical; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Papillary; Cystosco | 1998 |
Detection of dysplastic lesions by fluorescence in a model of colitis in rats after previous photosensitization with 5-aminolaevulinic acid.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Chi-Square Distribution; Chronic Disease; Colitis; Colo | 1998 |
Technical principles for protoporphyrin-IX-fluorescence guided microsurgical resection of malignant glioma tissue.
Topics: Aminolevulinic Acid; Brain; Brain Neoplasms; Glioma; Humans; Image Processing, Computer-Assisted; Mi | 1998 |
Fluorescence cystoscopy in the diagnostics and treatment of bladder tumors.
Topics: Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopes; Endoscope | 1998 |
5-aminolevulinic acid-induced fluorescence endoscopy applied at secondary transurethral resection after conventional resection of primary superficial bladder tumors.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Fluorescence; Humans; Male; | 1999 |
Clinical spectral characterisation of colonic mucosal lesions using autofluorescence and delta aminolevulinic acid sensitisation.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Colon; Colonic Neoplasms; Colonoscopy; | 1999 |
Clinical results of the transurethreal resection and evaluation of superficial bladder carcinomas by means of fluorescence diagnosis after intravesical instillation of 5-aminolevulinic acid.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma | 1999 |
Diagnosis of bladder carcinoma using protoporphyrin IX fluorescence induced by 5-aminolaevulinic acid.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Fluorescence; Humans; Male; | 1999 |
[Visualizing carcinomas of the mouth cavity by stimulating synthesis of fluorescent protoporphyrin IX].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Female; Humans; Male; Middle Aged; Mout | 1999 |
[Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis or colorectal adenomas].
Topics: Adenomatous Polyps; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Colitis, Ulcerative; Colorectal | 1999 |
Evaluation of novel nonlaser light source for endometrial ablation using 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Endometrium; Female; Laser Therapy; Necrosis; | 1999 |
Fluorescence staining of laryngeal neoplasms after topical application of 5-aminolevulinic acid: preliminary results.
Topics: Administration, Topical; Aminolevulinic Acid; Biopsy; Evaluation Studies as Topic; Humans; Laryngeal | 1999 |
Detection of squamous cell carcinoma of the oral cavity by imaging 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
Topics: Adult; Aged; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Humans; Middle Aged; Mouth; Mout | 2000 |
Capillary zone electrophoresis/mass spectrometry of 5-aminolaevulinic acid and porphobilinogen.
Topics: Aminolevulinic Acid; Electrophoresis, Capillary; Mass Spectrometry; Porphobilinogen; Sensitivity and | 2000 |
Blood lead level to induce significant increase in urinary delta-aminolevulinic acid level among lead-exposed workers: a statistical approach.
Topics: Adult; Aminolevulinic Acid; Biomarkers; Female; Humans; Lead; Male; Occupational Exposure; Photosens | 2000 |
Validation of a capillary electrophoresis method for determination of 5-aminolevulinic acid and degradation products.
Topics: Aminolevulinic Acid; Electrophoresis, Capillary; Reproducibility of Results; Sensitivity and Specifi | 2000 |
[Photodiagnostic tests. 3: Fluorescence diagnosis with delta-aminolevulinic acid-induced porphyrins (FDAP) in dermatology].
Topics: Aminolevulinic Acid; Fluorescence; Humans; Porphyrins; Sensitivity and Specificity; Skin; Skin Disea | 2000 |
Sensitivity analysis of the diagnostic value of endoscopies in cross-sectional studies in the absence of a gold standard.
Topics: Aminolevulinic Acid; Cross-Sectional Studies; Cystoscopy; Female; Humans; Male; Predictive Value of | 2000 |
Fluorescence detection of small gastrointestinal tumours: principles, technique, first clinical experience.
Topics: Aminolevulinic Acid; Endoscopy; Fluorescence; Gastrointestinal Neoplasms; Humans; Laparoscopy; Perit | 2000 |
Endoscopic fluorescence detection of low and high grade dysplasia in Barrett's oesophagus using systemic or local 5-aminolaevulinic acid sensitisation.
Topics: Administration, Oral; Administration, Topical; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Esoph | 2001 |
[Fluorescence-assisted biopsy of basal cell carcinomas].
Topics: Administration, Topical; Aminolevulinic Acid; Biopsy; Carcinoma, Basal Cell; Fluorescence; Humans; I | 2000 |
Systemic vs local administration of delta-aminolevulinic acid for laparoscopic fluorescence diagnosis of malignant intra-abdominal tumors. Experimental study.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Fluorescence Polarization; Injections, Intrape | 2001 |
Role of 5-aminolevulinic acid in the diagnosis and treatment of superficial bladder cancer: improvement in diagnostic sensitivity.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluorescence; Humans; Male; | 2001 |
[Fluorescence cytology of the urinary bladder].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Humans; Microscopy | 2001 |
An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part I. Design, spectral and spatial characteristics.
Topics: Aminolevulinic Acid; Equipment Design; Humans; Image Processing, Computer-Assisted; Photosensitizing | 2001 |
Autofluorescence imaging to optimize 5-ALA-induced fluorescence endoscopy of bladder carcinoma.
Topics: Administration, Intravesical; Aminolevulinic Acid; Biopsy; Cystoscopy; Equipment Design; False Posit | 2001 |
Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cystoscopy; Femal | 2001 |
Fluorescence induced with 5-aminolevulinic acid for the endoscopic detection and follow-up of esophageal lesions.
Topics: Administration, Oral; Aged; Aminolevulinic Acid; Biopsy; Esophageal Neoplasms; Esophagoscopy; Female | 2001 |
Photodynamic therapy with 5-aminolevulinic acid is not effective in bile duct cancer.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aminolevulinic Acid; Bile Duct Neoplasms; Cholangiogr | 2001 |
A comparative study of normal inspection, autofluorescence and 5-ALA-induced PPIX fluorescence for oral cancer diagnosis.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Female; Fluor | 2002 |
New aspect of photodynamic diagnosis of bladder tumors: fluorescence cytology.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Anthracenes; Carcinoma in Situ; Cystitis; Cytophotomet | 2002 |
Endoscopic fluorescence detection of low and high grade dysplasia in Barrett's oesophagus using systemic or local 5-aminolaevulinic acid sensitization.
Topics: Administration, Oral; Administration, Topical; Aminolevulinic Acid; Barrett Esophagus; Cell Transfor | 2002 |
[Re-assessment of indicators for screening lead poisoning].
Topics: 5'-Nucleotidase; Adult; Aminolevulinic Acid; Female; Humans; Lead; Lead Poisoning; Male; Mass Screen | 1999 |
Comparison of the bladder tumour antigen test with photodynamic diagnosis in patients with pathologically confirmed recurrent superficial urinary bladder tumours.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Antigens, Neoplasm; Biomarkers, Tumor; Cystosco | 2002 |
[Fluorescent endoscopy superior to white light endoscopy. Detecting cancers of the urinary bladder earlier].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Fluorescence; Huma | 2002 |
[5-aminolevulinic acid induced fluorescence for the detection of oesophageal lesions].
Topics: Aminolevulinic Acid; Esophageal Neoplasms; Esophagoscopy; Esophagus; Fluorescence; Humans; Precancer | 2002 |
Comparison between 5-aminolevulinic acid photodynamic diagnosis and narrow-band imaging for bladder cancer detection.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Humans; Levulinic Acids; Male; Mid | 2021 |
Effectiveness of Photodynamic Screening Using 5-Aminolevulinic Acid for the Diagnosis of Pancreatic Cancer.
Topics: Aged; Aminolevulinic Acid; Biomarkers; Biomarkers, Tumor; Early Detection of Cancer; Female; Humans; | 2020 |