Proteins > NPC1-like intracellular cholesterol transporter 1
Page last updated: 2024-08-07 19:47:52
NPC1-like intracellular cholesterol transporter 1
An NPC1-like intracellular cholesterol transporter 1 that is encoded in the genome of rat. [OMA:Q6T3U3, PRO:DNx]
Synonyms
Niemann-Pick C1-like protein 1
Research
Bioassay Publications (2)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (2)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| ezetimibe | Rattus norvegicus (Norway rat) | Ki | 0.2000 | 1 | 1 |
| sch 60663 | Rattus norvegicus (Norway rat) | IC50 | 0.5800 | 1 | 1 |
| sch 60663 | Rattus norvegicus (Norway rat) | Ki | 0.1800 | 1 | 1 |
Spiroimidazolidinone NPC1L1 inhibitors. 1: Discovery by 3D-similarity-based virtual screening.Bioorganic & medicinal chemistry letters, , Jun-01, Volume: 19, Issue:11, 2009
Substituted oxazolidinones as novel NPC1L1 ligands for the inhibition of cholesterol absorption.Bioorganic & medicinal chemistry letters, , Jan-15, Volume: 18, Issue:2, 2008