Page last updated: 2024-08-07 12:40:29

POsterior Segregation

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (120)

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
3,4-dihydroxyphenylacetic acidCaenorhabditis elegansEC5049.832010
6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolCaenorhabditis elegansEC50300.000010
benserazideCaenorhabditis elegansEC501,350.000010
hexachloropheneCaenorhabditis elegansEC5045.445010
masoprocolCaenorhabditis elegansEC5026.111010
protoporphyrin ixCaenorhabditis elegansEC509.949010
methylene blueCaenorhabditis elegansEC50186.681010
quinophthaloneCaenorhabditis elegansEC50300.000010
yohimbineCaenorhabditis elegansEC50300.000010
rheinCaenorhabditis elegansEC5029.176010
neutral red baseCaenorhabditis elegansEC5013.004010
malononitrile dimerCaenorhabditis elegansEC5054.854010
lysergolCaenorhabditis elegansEC5020.605010
isoetharine mesylateCaenorhabditis elegansEC50300.000010
benserazide hydrochlorideCaenorhabditis elegansEC5037.451010
epigallocatechin gallateCaenorhabditis elegansEC505.892010
dimidium bromideCaenorhabditis elegansEC5013.509010
methyl fluorone blackCaenorhabditis elegansEC501.897010
agroclavineCaenorhabditis elegansEC5011.174010
2,4,6-tripyridyl-s-triazineCaenorhabditis elegansEC5031.054010
oxoglaucineCaenorhabditis elegansEC5068.553010
paxillineCaenorhabditis elegansEC5016.719010
pyrophenCaenorhabditis elegansEC5038.668010
sk&f-38393Caenorhabditis elegansEC50108.546010
sb 216763Caenorhabditis elegansEC5025.978010
4-(2-methyl-5-phenyl-1-pyrrolyl)benzoic acidCaenorhabditis elegansEC50300.000010
2-carbazol-9-ylbenzoic acidCaenorhabditis elegansEC50300.000010
(R)-RoemerineCaenorhabditis elegansEC5016.837010
oxopurpureineCaenorhabditis elegansEC5028.614010
3,6-bis(2-pyridyl)-1,2,4,5-tetrazineCaenorhabditis elegansEC50300.000010
18-Hydroxy-11,17-dimethoxyyohimban-16-carboxylic acidCaenorhabditis elegansEC50300.000010
(R)-norlaudanosolineCaenorhabditis elegansEC506.359010
resveratrolCaenorhabditis elegansEC50300.000010
2-phenoxy-N-(2-pyridinyl)butanamideCaenorhabditis elegansEC50300.000010
2-(N-[2-(1-benzotriazolyl)-1-oxoethyl]-4-methoxyanilino)-N-(2-methylbutan-2-yl)-2-(1-methyl-2-pyrrolyl)acetamideCaenorhabditis elegansEC50300.000010
6-hydroxy-1-(3-hydroxypropyl)-4-methyl-2-oxo-5-(1-piperidinylmethyl)-3-pyridinecarbonitrileCaenorhabditis elegansEC50300.000010
2-cyano-N-(3-methoxypropyl)-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetamideCaenorhabditis elegansEC5023.830010
N-ethyl-2-imino-10-methyl-1-[(4-methylphenyl)methyl]-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideCaenorhabditis elegansEC50300.000010
7-(diethylamino)-2-oxo-1-benzopyran-3-carbonitrileCaenorhabditis elegansEC5076.301010
6-amino-5-(methylamino)-1-(phenylmethyl)pyrimidine-2,4-dioneCaenorhabditis elegansEC50300.000010
N'-[(4-chlorophenyl)-oxomethyl]-2-pyrazinecarbohydrazideCaenorhabditis elegansEC5095.863010
2-bromo-N-(3-methoxyphenyl)benzamideCaenorhabditis elegansEC50300.000010
2-phenyl-3-imidazo[1,2-a]pyridinecarboxaldehydeCaenorhabditis elegansEC50300.000010
1-[[(1,5-dimethyl-3-pyrazolyl)-oxomethyl]amino]-3-(2-methoxyphenyl)thioureaCaenorhabditis elegansEC5050.254010
3-(3-formyl-2,5-dimethyl-1-pyrrolyl)-4-methylbenzoic acid methyl esterCaenorhabditis elegansEC50300.000010
umi-77Caenorhabditis elegansEC5020.723010
7-anilino-1-(4-methylphenyl)-5-oxo-[1,2,4]triazolo[4,3-a]pyrimidine-3-carboxylic acid ethyl esterCaenorhabditis elegansEC5078.248010
2-imino-10-methyl-N-[2-(4-morpholinyl)ethyl]-5-oxo-1-(3-pyridinylmethyl)-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideCaenorhabditis elegansEC50300.000010
2-[2,5-dimethyl-3-[(2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1-pyrrolyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid ethyl esterCaenorhabditis elegansEC50300.000010
2-[[3-(3,4-dimethoxyphenyl)-2-oxo-1-benzopyran-7-yl]oxy]acetamideCaenorhabditis elegansEC50300.000010
3-amino-8-methyl-N-[4-(4-morpholinyl)phenyl]-2-thieno[2,3-b]quinolinecarboxamideCaenorhabditis elegansEC50300.000010
2-(4-chlorophenoxy)-4-(dimethylamino)-3-pyridinecarbonitrileCaenorhabditis elegansEC50300.000010
1,4-benzoquinone guanylhydrazone thiosemicarbazoneCaenorhabditis elegansEC5076.496010
5-bromo-N-(2-fluorophenyl)-6-oxo-3-pyrancarboxamideCaenorhabditis elegansEC50300.000010
1-[2-[(2-methylphenyl)methylthio]ethyl]-3-phenylthioureaCaenorhabditis elegansEC50300.000010
2,8-dimercapto-6-hydroxypurineCaenorhabditis elegansEC5032.038010
1,3-benzothiazole-6-carboxylic acid [2-(2-furanyl)-2-oxoethyl] esterCaenorhabditis elegansEC50300.000010
5-(methoxymethyl)-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-oneCaenorhabditis elegansEC50300.000010
N'-benzoyl-2-(3-pyridinyl)-4-thiazolecarbohydrazideCaenorhabditis elegansEC50300.000010
2-amino-4-(4,5-dimethoxy-2-nitrophenyl)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-1-benzopyran-3-carbonitrileCaenorhabditis elegansEC5019.454010
2-amino-7-methyl-5-oxo-4-(2,3,4-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrileCaenorhabditis elegansEC50300.000010
2-amino-7-methyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydro-1-benzopyran-3-carbonitrileCaenorhabditis elegansEC50300.000010
1-hexadecyl-3-methylimidazolium bromideCaenorhabditis elegansEC50300.000010
2-cyano-N-(phenylmethyl)-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetamideCaenorhabditis elegansEC50300.000010
2-benzoyl-N-(6-methoxy-3-pyridinyl)-3,4-dihydro-1H-isoquinoline-3-carboxamideCaenorhabditis elegansEC5025.113010
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolineCaenorhabditis elegansEC50300.000010
4-(6-bromo-1,3-benzodioxol-5-yl)-7,9-dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolineCaenorhabditis elegansEC50300.000010
1-[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]ethanoneCaenorhabditis elegansEC50300.000010
N-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]-2-nitrobenzamideCaenorhabditis elegansEC50133.712010
2-imino-1-[(4-methylphenyl)methyl]-5-oxo-N-(2-oxolanylmethyl)-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamideCaenorhabditis elegansEC50300.000010
6-amino-2-ethyl-8-[2-(trifluoromethyl)phenyl]-1,6,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrileCaenorhabditis elegansEC50260.324010
2-(3-ethoxypropylamino)-8-methyl-5-oxo-N-(2-oxolanylmethyl)-3-dipyrido[1,2-pyrimidinecarboxamideCaenorhabditis elegansEC50300.000010
5-[(4-fluorophenyl)methylsulfonylmethyl]-N-(2-oxolanylmethyl)-2-furancarboxamideCaenorhabditis elegansEC50300.000010
4-[[2-[[cyclohexyl(oxo)methyl]amino]-1-oxo-3-phenylpropyl]amino]-1-piperidinecarboxylic acid ethyl esterCaenorhabditis elegansEC50300.000010
4-morpholinecarboxylic acid [4-(2-amino-3-cyano-5-oxo-4,6,7,8-tetrahydro-1-benzopyran-4-yl)-2,6-dimethoxyphenyl] esterCaenorhabditis elegansEC50300.000010
4-[3-(1,3-diphenyl-4-pyrazolyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-4-oxobutanoic acidCaenorhabditis elegansEC5046.519010
6-(5,6-Dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acidCaenorhabditis elegansEC5027.245010
4-(3,5-dimethyl-1-piperidinyl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-4-oxobutanamideCaenorhabditis elegansEC50300.000010
N,6-dimethyl-2-[[[4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl]-oxomethyl]amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamideCaenorhabditis elegansEC50300.000010
5-(3,4-dimethoxyphenyl)-3-(2-furanylmethyl)-4-imino-5H-[1]benzopyrano[2,3-d]pyrimidin-8-olCaenorhabditis elegansEC50300.000010
luteolinCaenorhabditis elegansEC5060.374010
methysergide maleateCaenorhabditis elegansEC5010.281010
myricitrinCaenorhabditis elegansEC5015.805010
rosmarinic acidCaenorhabditis elegansEC5013.604010
4-[(3aR,4S,9bS)-8-[(4-methoxyphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acidCaenorhabditis elegansEC5014.296010
semaxinibCaenorhabditis elegansEC50300.000010
2-(4-(dimethylamino)styryl)benzothiazoleCaenorhabditis elegansEC50300.000010
1,5-dioxo-2,4-dihydropyrrolo[1,2-a]quinazoline-3-carboxylic acid ethyl esterCaenorhabditis elegansEC5089.039010
quinaldine redCaenorhabditis elegansEC50300.000010
2',3,4-trihydroxychalconeCaenorhabditis elegansEC50300.000010
3-amino-5-(4-bromophenyl)-4-pyridazinecarbonitrileCaenorhabditis elegansEC5053.523010
cefdinirCaenorhabditis elegansEC5049.794010
altenusinCaenorhabditis elegansEC5030.968010
1-(3,4-dimethylphenyl)-2,5-dioxo-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarbonitrileCaenorhabditis elegansEC50300.000010
mdl 105725Caenorhabditis elegansEC5014.438010
3-amino-2-cyano-5-(3-methoxyphenyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid methyl esterCaenorhabditis elegansEC50300.000010
2-hydroxyapomorphine, (r)-isomerCaenorhabditis elegansEC505.410010
N-butyl-N-methyl-4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxobutanamideCaenorhabditis elegansEC50181.127520
[5-Chloranyl-3-[(1E,3E)-3,5-dimethylhepta-1,3-dienyl]-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] ethanoateCaenorhabditis elegansEC50300.000010
N-[3-(diethylamino)propyl]-4-[(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazo]-4-oxobutanamideCaenorhabditis elegansEC5081.076020
violaceol IICaenorhabditis elegansEC5043.938010
2-(2-acetyl-3,5-dihydroxyphenyl)acetic acidCaenorhabditis elegansEC50300.000010
cyclopenolCaenorhabditis elegansEC504.129010
N-[5-[methyl-(3-methylphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl]-2-furancarboxamideCaenorhabditis elegansEC50300.000010
N-[1-(3-fluorophenyl)-6,6-dimethyl-5,7-dihydro-4H-indazol-4-yl]-2-(2-pyridinylthio)acetamideCaenorhabditis elegansEC50300.000010
3-[[1-[1-(methylthio)propan-2-yl]-4-piperidinyl]oxy]-N-(2-pyridinylmethyl)benzamideCaenorhabditis elegansEC5034.866010
2-(4-morpholinyl)-N'-[(2-nitrophenyl)-oxomethyl]-4-thiazolecarbohydrazideCaenorhabditis elegansEC50101.968020
2-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-1H-quinazolin-4-oneCaenorhabditis elegansEC50300.000010

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
5,8,11,14-eicosatetraynoic acidCaenorhabditis elegansAC5010.780010
s-2678Caenorhabditis elegansAC503.298010
4-(2-thiazolylazo)resorcinolCaenorhabditis elegansAC5019.067010
sch 45752Caenorhabditis elegansAC508.292010
raubasineCaenorhabditis elegansAC507.169010
LSM-16248Caenorhabditis elegansAC508.045010
N'-[(2-nitrophenyl)-oxomethyl]-2-pyridinecarbohydrazideCaenorhabditis elegansAC5021.218010
N1',N6'-bis[(5-methyl-1H-pyrazol-3-yl)-oxomethyl]hexanedihydrazideCaenorhabditis elegansAC50100.000010
2-[[3-(3-oxo-1,2-benzothiazol-2-yl)phenyl]sulfonylamino]benzoic acidCaenorhabditis elegansAC508.717010
N-(6-methoxy-3-pyridinyl)-7-methyl-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamideCaenorhabditis elegansAC5024.615010
4'-epichaetoviridin ACaenorhabditis elegansAC5014.554010
methacycline monohydrochlorideCaenorhabditis elegansAC5011.359010