Proteins > Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120
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Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120
[no definition available]
Synonyms
Research
Bioassay Publications (5)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
Compounds (5)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| efavirenz | Human immunodeficiency virus 1 | IC50 | 0.0035 | 1 | 1 |
| nbd 556 | Human immunodeficiency virus 1 | IC50 | 1.8775 | 4 | 4 |
| bms 806 | Human immunodeficiency virus 1 | IC50 | 8.7000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| bms-488043 | Human immunodeficiency virus 1 | Kd | 0.0190 | 1 | 1 |
| bms-626529 | Human immunodeficiency virus 1 | Kd | 0.0008 | 1 | 1 |
Exploratory studies on soluble small molecule CD4 mimics as HIV entry inhibitors.Bioorganic & medicinal chemistry, , 02-15, Volume: 56, 2022
Hybrids of Small-Molecule CD4 Mimics with Polyethylene Glycol Units as HIV Entry Inhibitors.Journal of medicinal chemistry, , 02-11, Volume: 64, Issue:3, 2021
Soluble-type small-molecule CD4 mimics as HIV entry inhibitors.Bioorganic & medicinal chemistry letters, , 03-01, Volume: 29, Issue:5, 2019