An ornithine decarboxylase that is encoded in the genome of rat. [OMA:P09057, PRO:DNx]
ODC;
EC 4.1.1.17
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 3-hydroxybenzylhydrazine | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 0 |
| p-chloromercuribenzoic acid | Rattus norvegicus (Norway rat) | Potency | 2.5119 | 1 | 0 |
| 4-imidazolemethanol | Rattus norvegicus (Norway rat) | Potency | 0.0032 | 1 | 0 |
| aurintricarboxylic acid | Rattus norvegicus (Norway rat) | Potency | 0.1585 | 1 | 0 |
| benzamidine | Rattus norvegicus (Norway rat) | Potency | 0.0631 | 1 | 0 |
| bml 190 | Rattus norvegicus (Norway rat) | Potency | 0.0079 | 1 | 0 |
| clemizole | Rattus norvegicus (Norway rat) | Potency | 0.0079 | 1 | 0 |
| dephostatin | Rattus norvegicus (Norway rat) | Potency | 3.9811 | 1 | 0 |
| disulfiram | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| ebselen | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 0 |
| felbamate | Rattus norvegicus (Norway rat) | Potency | 0.0100 | 1 | 0 |
| fusaric acid | Rattus norvegicus (Norway rat) | Potency | 0.2512 | 1 | 0 |
| hydralazine | Rattus norvegicus (Norway rat) | Potency | 7.9433 | 1 | 0 |
| indirubin-3'-monoxime | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 0 |
| nsc 664704 | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 0 |
| mitoxantrone | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 0 |
| moxisylyte | Rattus norvegicus (Norway rat) | Potency | 0.0126 | 1 | 0 |
| fg 7142 | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 0 |
| n 0840 | Rattus norvegicus (Norway rat) | Potency | 0.0063 | 1 | 0 |
| niclosamide | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 0 |
| niflumic acid | Rattus norvegicus (Norway rat) | Potency | 0.0251 | 1 | 0 |
| ns 2028 | Rattus norvegicus (Norway rat) | Potency | 0.0126 | 1 | 0 |
| oxatomide | Rattus norvegicus (Norway rat) | Potency | 0.0251 | 1 | 0 |
| pd 98059 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 0 |
| pirenperone | Rattus norvegicus (Norway rat) | Potency | 0.0063 | 1 | 0 |
| riluzole | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| ritanserin | Rattus norvegicus (Norway rat) | Potency | 0.0063 | 1 | 0 |
| sanguinarine | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 0 |
| sb 206553 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 0 |
| triamterene | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 0 |
| trifluperidol | Rattus norvegicus (Norway rat) | Potency | 0.0050 | 1 | 0 |
| pseudoephedrine | Rattus norvegicus (Norway rat) | Potency | 7.9433 | 1 | 0 |
| suramin sodium | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 0 |
| d-glutamate | Rattus norvegicus (Norway rat) | Potency | 0.0050 | 1 | 0 |
| rutecarpine | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 0 |
| n-acetyltryptamine | Rattus norvegicus (Norway rat) | Potency | 2.5119 | 1 | 0 |
| beta-carboline-3-carboxylic acid methyl ester | Rattus norvegicus (Norway rat) | Potency | 2.5119 | 1 | 0 |
| uh 301 | Rattus norvegicus (Norway rat) | Potency | 0.0063 | 1 | 0 |
| pre 084 | Rattus norvegicus (Norway rat) | Potency | 0.0126 | 1 | 0 |
| n-(2-chloroethyl)-4-piperidinyl diphenylacetate | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 0 |
| dexefaroxan | Rattus norvegicus (Norway rat) | Potency | 0.0200 | 1 | 0 |
| 6-bromoindirubin-3'-oxime | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 0 |
| gw9662 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 0 |
| ag-213 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 0 |
| sch-202676 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| 4-bromotetramisole, (s)-isomer | Rattus norvegicus (Norway rat) | Potency | 100.0000 | 1 | 0 |
| phenylthiazolylthiourea | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| (2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine) | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 0 |
| cis-resveratrol | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 0 |
| 6-methyl-2-(phenylethynyl)pyridine | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)urea | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 0 |
| sib 1757 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 0 |
| apigenin | Rattus norvegicus (Norway rat) | Potency | 3.1623 | 1 | 0 |
| genistein | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| daidzein | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| tranilast | Rattus norvegicus (Norway rat) | Potency | 19.9526 | 1 | 0 |
| tyrphostin ag-494 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| ag-490 | Rattus norvegicus (Norway rat) | Potency | 0.0063 | 1 | 0 |
| ag 112 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 0 |
| nf023 | Rattus norvegicus (Norway rat) | Potency | 25.1189 | 1 | 0 |
| nf 449 | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 0 |
| 7-chloro-4-hydroxy-2-phenyl-1,8-naphthyridine | Rattus norvegicus (Norway rat) | Potency | 3.9811 | 1 | 0 |
| (8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 0 |
| dihydrexidine | Rattus norvegicus (Norway rat) | Potency | 0.1995 | 1 | 0 |
| pd 404182 | Rattus norvegicus (Norway rat) | Potency | 7.9433 | 1 | 0 |
| lfm a13 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 0 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| putrescine | Rattus norvegicus (Norway rat) | Ki | 3,500.0000 | 1 | 1 |
| alpha-methylornithine | Rattus norvegicus (Norway rat) | Ki | 40.0000 | 1 | 1 |
| eflornithine | Rattus norvegicus (Norway rat) | Ki | 39.0000 | 1 | 1 |
| 1-aminooxy-3-aminopropane | Rattus norvegicus (Norway rat) | IC50 | 0.0350 | 1 | 1 |
| 2-fluoromethylornithine | Rattus norvegicus (Norway rat) | Ki | 38.8500 | 2 | 2 |
| cangrelor | Rattus norvegicus (Norway rat) | IC50 | 0.0004 | 1 | 1 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid | Rattus norvegicus (Norway rat) | ID50 | 0.0001 | 1 | 1 |
| 6-(1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-naphthyl)-2-naphthalenecarboxylic acid | Rattus norvegicus (Norway rat) | ID50 | 0.0022 | 1 | 1 |
| tretinoin | Rattus norvegicus (Norway rat) | ID50 | 0.0000 | 1 | 1 |
| 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid | Rattus norvegicus (Norway rat) | ID50 | 0.0000 | 1 | 1 |