Page last updated: 2024-08-02 22:03:29

carbon-11 methionine

Description

carbon-11 methionine: RN refers to L-methionine labeled with carbon-11 [MeSH]

Cross-References

ID SourceID
PubMed CID15556483
CHEMBL ID2106977
MeSH IDM0228645

Synonyms (6)

Synonym
carbon-11 methionine
methionine c 11
58576-49-1
D04984
CHEMBL2106977
methionine-c11

Research

Studies (157)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's28 (17.83)18.2507
2000's38 (24.20)29.6817
2010's69 (43.95)24.3611
2020's22 (14.01)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials19 (11.73%)5.53%
Reviews10 (6.17%)6.00%
Case Studies35 (21.60%)4.05%
Observational1 (0.62%)0.25%
Other97 (59.88%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
5-hydroxytryptophanhydroxytryptophanhuman metabolite;
neurotransmitter
201820186.0low000010
cholinecholinesallergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite
2003201117.0low100220
lactic acid2-hydroxy monocarboxylic acidalgal metabolite;
Daphnia magna metabolite
202120213.0low000001
dihydroxyphenylalaninehydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative
human metabolite1996202114.5low101111
racemethioninealpha-amino acid;
amino acid zwitterion;
sulfur-containing amino acid
algal metabolite;
Daphnia magna metabolite;
Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
202320231.0low000004
fluorouracilnucleobase analogue;
organofluorine compound
antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic
2003200321.0low100100
iohexolbenzenedicarboxamide;
organoiodine compound
environmental contaminant;
radioopaque medium;
xenobiotic
2013201311.0low000010
iopromidedicarboxylic acid diamide;
organoiodine compound
environmental contaminant;
nephrotoxic agent;
radioopaque medium;
xenobiotic
2013201311.0low000010
sodium fluoridefluoride saltmutagen2012201212.0low000010
temozolomideimidazotetrazine;
monocarboxylic acid amide;
triazene derivative
alkylating agent;
antineoplastic agent;
prodrug
2006202112.0low200211
methionineaspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid
antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical
1994202314.2high19030397216
ephedrinephenethylamine alkaloid;
phenylethanolamines
bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic
201820186.0low000010
azomycinC-nitro compound;
imidazoles
antitubercular agent202020204.0low000010
3-hydroxyephedrine201820186.0low000010
gadoliniumf-block element atom;
lanthanoid atom
2009201213.5low000110
thallium chlorideinorganic chloride;
thallium molecular entity
2003200321.0low000100
misonidazole2011201113.0low100010
fluorodopa f 18(18)F radiopharmaceutical;
6-fluoro-L-dopa
1996202114.5low101111
fluorodeoxyglucose f182-deoxy-2-((18)F)fluoro-D-glucose;
2-deoxy-2-fluoro-aldehydo-D-glucose
1995202316.7medium301612233
fluoromisonidazole2011201113.0low100010
deoxyglucose1995199728.0low007000
3-iodo-alpha-methyltyrosine2003200321.0low000100
methotrexatedicarboxylic acid;
monocarboxylic acid amide;
pteridines
abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent
2012201212.0low000010
thalliumboron group element atom2003200321.0low000100
cysteinecysteiniumfundamental metabolite1998199826.0low001000
gadolinium dtpagadolinium coordination entityMRI contrast agent2012201212.0low000010
18f-faza202020204.0low000010
technetium tc 99m exametazime1996200225.0low001100
mefloquine2014201410.0low000010
cholecystokinin202020204.0low000010
technetium tc 99m sestamibi200320239.6low200242
dacarbazinedacarbazine2006201215.0low200210
technetium tc 99m bicisate1998199826.0low001000
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Aberrant Tissue01996201518.5low001010
Absence Seizure01998202214.0low001001
Acquired Language Disorders01999199925.0low001000
Adenocarcinoma01994199430.0low001000
Adenocarcinoma, Basal Cell01994199430.0low001000
Adenoma01996202313.4low001461
Adenoma, Basal Cell01996202313.4low001461
Adenomatosis, Familial Endocrine0201820186.0low000010
Adrenocorticotropic Hormone, Inappropriate Secretion0202320231.0low000001
Age-Related Memory Disorders01999199925.0low001000
Aging02011201113.0low000010
AIDS-Associated Lymphoma01997199727.0low001000
AIDS-Related Opportunistic Infections01997199727.0low001000
Anaplastic Astrocytoma01995202119.4low005121
Anaplastic Ependymoma01996199628.0low001000
Anaplastic Oligodendroglioma0202120213.0low000001
Angioblastic Meningioma01996201319.5low001010
Anterior Cerebral Circulation Infarction0201220208.0low000020
Anterior Choroidal Artery Infarction02002200222.0low000100
Argentaffinoma0202020204.0low000010
Astroblastoma02011201113.0low000010
Astrocytoma01995202119.4low005121
Astrocytoma, Grade IV01996202311.9low302163
Atrophy02003200321.0low000100
Aura01998199826.0low001000
Auricular Cancer01995199529.0low001000
Benign Frontal Childhood Epilepsy01996199628.0low001000
Benign Meningeal Neoplasms01996201317.0low001020
Benign Neoplasms02001202312.0low000121
Benign Neoplasms, Brain01994202314.4medium1001319288
Benign Supratentorial Neoplasms01996199628.0low001000
Besnier-Boeck Disease02004200420.0low000100
Bilateral Headache02004200420.0low000100
Bone Cancer01996200921.5low001100
Bone Neoplasms01996200921.5low001100
Brachial Paresis02003200321.0low000100
Brain Abscess02003200321.0low000100
Brain Diseases01998201219.0low001010
Brain Disorders01998201219.0low001010
Brain Hemorrhage, Cerebral02002200222.0low000100
Brain Infarction0201220208.0low000020
Brain Inflammation02012201212.0low000020
Brain Neoplasms01994202314.4medium1001319288
Brain Stem Neoplasms02011201113.0low000010
Brain Stem Neoplasms, Primary02011201113.0low000010
Breast Cancer01996200919.3low001200
Breast Neoplasms01996200919.3low001200
Cancer of Cervix01994199430.0low001000
Cancer of Endometrium01994199430.0low001000
Cancer of Head01998200623.0low102100
Cancer of Larynx0201920195.0low000010
Cancer of Lung01995200922.8low105300
Cancer of Mediastinum01998199826.0low001000
Cancer of Nose01995199529.0low001000
Cancer of Ovary0202020204.0low000010
Cancer of Parathyroid01996202313.2low001471
Cancer of Pituitary02013201311.0low000010
Cancer of Rectum02002200222.0low100100
Cancer of Skin01995199529.0low001000
Cancer, Embryonal02009200915.0low000100
Cancer, Radiation-Induced0201820186.0low000010
Carcinoid Tumor0202020204.0low000010
Carcinoma0201920195.0low000010
Carcinoma, Adenosquamous01994199430.0low001000
Carcinoma, Anaplastic0201920195.0low000010
Carcinoma, Epidermoid01994200325.7low102100
Carcinoma, Non-Small Cell Lung02009200915.0low000100
Carcinoma, Non-Small-Cell Lung02009200915.0low000100
Carcinoma, Squamous Cell01994200325.7low102100
Cardiovascular Stroke02009200915.0low000100
Central Nervous System Cysts0201520159.0low000010
Central Nervous System Neoplasm0201020208.0low000120
Central Nervous System Neoplasms0201020208.0low000120
Central Nervous System Toxoplasmosis01997199727.0low001000
Cerebral Hemorrhage02002200222.0low000100
Cerebral Infarction02002200222.0low000100
Chronic Kidney Failure02006200618.0low100100
Clinically Isolated CNS Demyelinating Syndrome02005200519.0low000100
Coin Lesion, Pulmonary02004200818.0low100200
Craniopharyngioma02013201311.0low000010
Craniopharyngioma, Adamantinous02013201311.0low000010
Demyelinating Diseases02005200519.0low000100
Diffuse Large B-Cell Lymphoma0201220238.3low000021
Diffuse Mixed Small and Large Cell Lymphoma01995200225.5low001100
Disease Exacerbation02002201414.5low100220
Dysembryoma0200920209.5low000110
Ear Neoplasms01995199529.0low001000
Encephalitis02012201212.0low000020
Encephalitis, JC Polyomavirus02014201410.0low000010
Endodermal Sinus Tumor02009200915.0low000100
Endometrial Neoplasms01994199430.0low001000
Ependymoma01996199628.0low001000
Epilepsy01998199826.0low001000
Experimental Neoplasms01997199727.0low001000
Fever of Unknown Origin01997199727.0low001000
Genetic Predisposition0201820186.0low000010
Germinoblastoma01994201022.0low001100
Germinoma02003202211.5low000101
Glial Cell Tumors01996202212.0low40311224
Glioblastoma01996202311.9low302163
Glioblastoma with Sarcomatous Component02013201311.0low000010
Glioma01996202212.0low40311224
Gliosarcoma02013201311.0low000010
Granuloma02004201116.5low000110
Granulomas02004201116.5low000110
Granulomatosis, Lymphomatoid0202220222.0low000001
Group A Strep Infection02003200321.0low000100
Head and Neck Neoplasms01998200623.0low102100
Headache02004200420.0low000100
Hematoma02002200222.0low000100
HIV Coinfection01997199727.0low001000
HIV Infections01997199727.0low001000
Hyperparathyroidism01996201516.4low301330
Hyperparathyroidism, Primary0201020235.8low000123
Hyperparathyroidism, Secondary02004200519.5low100200
Hyperplasia01996201516.7low001020
Hyperthyroid02005200519.0low000100
Hyperthyroidism02005200519.0low000100
Hypertrophy02012201212.0low000010
Hypopharyngeal Cancer02003200321.0low100100
Hypopharyngeal Neoplasms02003200321.0low100100
Infarct, Lacunar0202020204.0low000010
Injuries, Radiation01996201918.4low202120
Invasiveness, Neoplasm02005201016.5low100200
Kahler Disease0201520206.5low000040
Kidney Failure, Chronic02006200618.0low100100
Language Disorders01999199925.0low001000
Laryngeal Neoplasms0201920195.0low000010
Leukoencephalopathy, Progressive Multifocal02014201410.0low000010
Local Neoplasm Recurrence01996202017.0low103340
Lung Neoplasms01995200922.8low105300
Lymph Node Metastasis01995200025.5low004000
Lymphatic Diseases01998199826.0low001000
Lymphoma01994201022.0low001100
Lymphoma, AIDS-Related01997199727.0low001000
Lymphoma, Large B-Cell, Diffuse0201220238.3low000021
Lymphoma, Non-Hodgkin01995200225.5low001100
Malignant Melanoma01995199529.0low001000
Mediastinal Neoplasms01998199826.0low001000
Melanoma01995199529.0low001000
Memory Disorders01999199925.0low001000
Meningeal Neoplasms01996201317.0low001020
Meningioma01996201319.5low001010
Meningitis02012201212.0low000010
Minimal Disease, Residual01996201817.0low101010
Morbid Obesity0201520159.0low000010
MS (Multiple Sclerosis)02005200519.0low000100
Multiple Myeloma0201520206.5low000040
Multiple Primary Neoplasms01996199628.0low001000
Multiple Sclerosis02005200519.0low000100
Myocardial Infarction02009200915.0low000100
Nausea02004200420.0low000100
Necrosis01996201916.5low201120
Neoplasm Metastasis, Unknown Primary01999199925.0low001000
Neoplasms02001202312.0low000121
Neoplasms, Germ Cell and Embryonal02009200915.0low000100
Neoplasms, Neuroepithelial02011201113.0low000010
Neoplasms, Plasma Cell02013201311.0low000010
Neoplasms, Skull Base0201620168.0low000010
Neurocytoma02004200420.0low000100
Obesity, Morbid0201520159.0low000010
Oligodendroglioma0202120213.0low000001
Orphan Diseases02004200420.0low000100
Ovarian Neoplasms0202020204.0low000010
Pachymeningitis02012201212.0low000010
Parathyroid Diseases02004200420.0low000100
Parathyroid Disorders02004200420.0low000100
Parathyroid Neoplasms01996202313.2low001471
Pituitary ACTH Hypersecretion0202320231.0low000001
Pituitary Neoplasms02013201311.0low000010
Primary Hyperparathyroidism0201020235.8low000123
Pulmonary Sarcoidosis01998199826.0low001000
Recrudescence0201020219.0low100171
Rectal Neoplasms02002200222.0low100100
Rhabdoid Tumor02012201212.0low000010
Sarcoidosis02004200420.0low000100
Sarcoidosis, Pulmonary01998199826.0low001000
Secondary Hyperparathyroidism02004200519.5low100200
Seizures01998202214.0low001001
Sensitivity and Specificity01996202116.2low110720112
Skin Neoplasms01995199529.0low001000
Soft Tissue Neoplasms01996200921.5low001100
Sparganosis02012201212.0low000010
Streptococcal Infections02003200321.0low000100
Teratoma0200920209.5low000110
Toxoplasmosis, Cerebral01997199727.0low001000
Uterine Cervical Neoplasms01994199430.0low001000
Yolk Sac Tumor02009200915.0low000100

Pharmacokinetics (3)

ArticleYear
Prognostic value of 11C-methionine volume-based PET parameters in IDH wild type glioblastoma.
PloS one, , Volume: 17, Issue:2
2022
Prognostic value of volume-based measurements on (11)C-methionine PET in glioma patients.
European journal of nuclear medicine and molecular imaging, , Volume: 42, Issue:7
2015
Quantitative volumetric analysis of gliomas with sequential MRI and ¹¹C-methionine PET assessment: patterns of integration in therapy planning.
European journal of nuclear medicine and molecular imaging, , Volume: 39, Issue:5
2012

Dosage (1)

ArticleYear
Potential significance of (11)C-methionine PET as a marker for the radiosensitivity of low-grade gliomas.
European journal of nuclear medicine and molecular imaging, , Volume: 29, Issue:5
2002