Page last updated: 2024-08-07 15:20:43

pyruvate kinase PKM isoform b

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (85)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
3-hydroxybenzylhydrazineHomo sapiens (human)Potency15.848920
p-chloromercuribenzoic acidHomo sapiens (human)Potency2.511920
4-imidazolemethanolHomo sapiens (human)Potency0.003220
aurintricarboxylic acidHomo sapiens (human)Potency0.158520
benzamidineHomo sapiens (human)Potency0.063120
bml 190Homo sapiens (human)Potency0.007920
clemizoleHomo sapiens (human)Potency0.007920
dephostatinHomo sapiens (human)Potency3.981120
disulfiramHomo sapiens (human)Potency25.118920
ebselenHomo sapiens (human)Potency10.000020
felbamateHomo sapiens (human)Potency0.010020
fusaric acidHomo sapiens (human)Potency0.251220
hydralazineHomo sapiens (human)Potency7.943320
indirubin-3'-monoximeHomo sapiens (human)Potency12.589320
nsc 664704Homo sapiens (human)Potency3.162320
mitoxantroneHomo sapiens (human)Potency19.952620
moxisylyteHomo sapiens (human)Potency0.012620
fg 7142Homo sapiens (human)Potency19.952620
n 0840Homo sapiens (human)Potency0.006320
niclosamideHomo sapiens (human)Potency3.162320
niflumic acidHomo sapiens (human)Potency0.025120
ns 2028Homo sapiens (human)Potency0.012620
oxatomideHomo sapiens (human)Potency0.025120
pd 98059Homo sapiens (human)Potency15.848920
pirenperoneHomo sapiens (human)Potency0.006320
riluzoleHomo sapiens (human)Potency25.118920
ritanserinHomo sapiens (human)Potency0.006320
sanguinarineHomo sapiens (human)Potency10.000020
sb 206553Homo sapiens (human)Potency6.309620
triamtereneHomo sapiens (human)Potency12.589320
trifluperidolHomo sapiens (human)Potency0.005020
pseudoephedrineHomo sapiens (human)Potency7.943320
suramin sodiumHomo sapiens (human)Potency31.622820
d-glutamateHomo sapiens (human)Potency0.005020
rutecarpineHomo sapiens (human)Potency3.162320
n-acetyltryptamineHomo sapiens (human)Potency2.511920
beta-carboline-3-carboxylic acid methyl esterHomo sapiens (human)Potency2.511920
uh 301Homo sapiens (human)Potency0.006320
pre 084Homo sapiens (human)Potency0.012620
n-(2-chloroethyl)-4-piperidinyl diphenylacetateHomo sapiens (human)Potency12.589320
dexefaroxanHomo sapiens (human)Potency0.020020
6-bromoindirubin-3'-oximeHomo sapiens (human)Potency15.848920
gw9662Homo sapiens (human)Potency39.810720
ag-213Homo sapiens (human)Potency39.810720
sch-202676Homo sapiens (human)Potency25.118920
4-bromotetramisole, (s)-isomerHomo sapiens (human)Potency100.000020
phenylthiazolylthioureaHomo sapiens (human)Potency25.118920
(2'-(4-aminophenyl)-(2,5'-bi-1h-benzimidazol)-5-amine)Homo sapiens (human)Potency15.848920
cis-resveratrolHomo sapiens (human)Potency3.162320
6-methyl-2-(phenylethynyl)pyridineHomo sapiens (human)Potency25.118920
n-(1-methyl-5-indolyl)-n'-(3-methyl-5-isothiazolyl)ureaHomo sapiens (human)Potency15.848920
sib 1757Homo sapiens (human)Potency6.309620
apigeninHomo sapiens (human)Potency3.162320
genisteinHomo sapiens (human)Potency25.118920
daidzeinHomo sapiens (human)Potency25.118920
tranilastHomo sapiens (human)Potency19.952620
tyrphostin ag-494Homo sapiens (human)Potency25.118920
ag-490Homo sapiens (human)Potency0.006320
ag 112Homo sapiens (human)Potency31.622820
nf023Homo sapiens (human)Potency25.118920
nf 449Homo sapiens (human)Potency31.622820
7-chloro-4-hydroxy-2-phenyl-1,8-naphthyridineHomo sapiens (human)Potency3.981120
(8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triolHomo sapiens (human)Potency39.810720
dihydrexidineHomo sapiens (human)Potency0.199520
pd 404182Homo sapiens (human)Potency7.943320
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-(4-fluorophenyl)sulfonylpiperazineHomo sapiens (human)Potency0.398110
[4-(2,6-difluorophenyl)sulfonyl-1-piperazinyl]-(2,3-dihydro-1,4-benzodioxin-6-yl)methanoneHomo sapiens (human)Potency0.000010
(2R)-1-(2,6-difluorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazineHomo sapiens (human)Potency0.000010
(2S)-4-(2,6-difluorophenyl)sulfonyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-2-methylpiperazineHomo sapiens (human)Potency0.562310
N-[1-(2,6-difluorophenyl)sulfonyl-4-piperidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency25.118910
1-(2,6-difluorophenyl)sulfonyl-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepaneHomo sapiens (human)Potency0.562310
N-[4-[(2,6-difluorophenyl)sulfonylamino]cyclohexyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency0.002210
1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[3-(trifluoromethyl)phenyl]sulfonylpiperazineHomo sapiens (human)Potency0.251210
N-[[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-3-azetidinyl]methyl]-2,6-difluorobenzenesulfonamideHomo sapiens (human)Potency44.668410
N-[1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-3-pyrrolidinyl]-2,6-difluorobenzenesulfonamideHomo sapiens (human)Potency63.095710
N-[3-[(2,6-difluorophenyl)sulfonylamino]propyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency39.810710
N-[5-[(2,6-difluorophenyl)sulfonylamino]pentyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency2.818410
N-[6-[(2,6-difluorophenyl)sulfonylamino]hexyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency39.810710
N-[2-[(2,6-difluorophenyl)sulfonylamino]ethyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency0.001810
N-[1-(2,6-difluorophenyl)sulfonyl-3-pyrrolidinyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency0.001810
N-[4-[(2,6-difluorophenyl)sulfonylamino]butyl]-2,3-dihydro-1,4-benzodioxin-6-sulfonamideHomo sapiens (human)Potency44.668410
2,4-dimethyl-6-phenyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency1.995310
3-[(2-fluorophenyl)methyl]-5-methyl-4-thieno[3,4]pyrrolo[1,3-d]pyrimidinoneHomo sapiens (human)Potency39.810710
6-[(2-fluorophenyl)methyl]-2-(1-hydroxyethyl)-4-methyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinoneHomo sapiens (human)Potency0.014110
lfm a13Homo sapiens (human)Potency15.848920