| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
acetylcarnitine
Acetylcarnitine: An acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS. | 2.45 | 2 | 0 | O-acylcarnitine | human metabolite |
ammonium hydroxide
azane : Saturated acyclic nitrogen hydrides having the general formula NnHn+2. | 1.99 | 1 | 0 | azane;
gas molecular entity;
mononuclear parent hydride | EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant |
betaine
glycine betaine : The amino acid betaine derived from glycine. | 2.07 | 1 | 0 | amino-acid betaine;
glycine derivative | fundamental metabolite |
carnitine
[no description available] | 3.39 | 7 | 0 | amino-acid betaine | human metabolite;
mouse metabolite |
gamma-butyrobetaine
4-(trimethylammonio)butanoate : An amino-acid betaine gamma-aminobutyric acid zwitterion in which all of the hydrogens attached to the nitrogen are replaced by methyl groups. | 2.07 | 1 | 0 | amino-acid betaine | Escherichia coli metabolite;
human metabolite |
valproic acid
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.. valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem. | 8.39 | 7 | 0 | branched-chain fatty acid;
branched-chain saturated fatty acid | anticonvulsant;
antimanic drug;
EC 3.5.1.98 (histone deacetylase) inhibitor;
GABA agent;
neuroprotective agent;
psychotropic drug;
teratogenic agent |
carbon tetrachloride
Carbon Tetrachloride: A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed). tetrachloromethane : A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups. | 1.98 | 1 | 0 | chlorocarbon;
chloromethanes | hepatotoxic agent;
refrigerant |
dimethylformamide
Dimethylformamide: A formamide in which the amino hydrogens are replaced by methyl groups.. N,N-dimethylformamide : A member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups. | 1.98 | 1 | 0 | formamides;
volatile organic compound | geroprotector;
hepatotoxic agent;
polar aprotic solvent |
pivalic acid
pivalic acid: RN given refers to parent cpd; structure. pivalic acid : A branched, short-chain fatty acid composed of propanoic acid having two methyl substituents at the 2-position. | 7.44 | 2 | 0 | branched-chain saturated fatty acid;
methyl-branched fatty acid;
short-chain fatty acid | |
s-adenosylmethionine
acylcarnitine: structure in first source. S-adenosyl-L-methioninate : A sulfonium betaine that is a conjugate base of S-adenosyl-L-methionine obtained by the deprotonation of the carboxy group. | 2.06 | 1 | 0 | sulfonium betaine | human metabolite |
propionylcarnitine
propionylcarnitine: RN given refers to cpd without isomeric designation | 2.07 | 1 | 0 | O-acylcarnitine | analgesic;
antirheumatic drug;
cardiotonic drug;
human metabolite;
peripheral nervous system drug |
octanoylcarnitine
octanoylcarnitine: RN given refers to cpd without isomeric designation. O-octanoyl-L-carnitine : The L-enantiomer of an O-octanoylcarnitine. | 1.96 | 1 | 0 | O-octanoylcarnitine;
saturated fatty acyl-L-carnitine | human metabolite |
3-hydroxyisovalerylcarnitine
3-hydroxyisovalerylcarnitine : An O-acylcarnitine having 3-hydroxyisovaleryl as the acyl substituent. | 2.06 | 1 | 0 | O-acylcarnitine | human metabolite |
pivaloylcarnitine
O-pivaloylcarnitine : A C5-acylcarnitine in which the acyl group specified is pivaloyl. | 7.44 | 2 | 0 | C5-acylcarnitine | metabolite |