Proteins > Squalene synthase
Page last updated: 2024-08-07 16:59:50

Squalene synthase

A squalene synthase that is encoded in the genome of rat. [OMA:Q02769, PRO:DNx]

Synonyms

SQS;
SS;
EC 2.5.1.21;
FPP:FPP farnesyltransferase;
Farnesyl-diphosphate farnesyltransferase

Research

Bioassay Publications (10)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's0 (0.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Compounds (13)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
acetazolamideRattus norvegicus (Norway rat)Ki0.009022
alprenololRattus norvegicus (Norway rat)IC504.200011
thiorphanRattus norvegicus (Norway rat)Ki10.000011
losartanRattus norvegicus (Norway rat)Ki0.005011
valsartanRattus norvegicus (Norway rat)Ki10.000012
cyc 202Rattus norvegicus (Norway rat)IC500.170011
resveratrolRattus norvegicus (Norway rat)IC5050.000011
farnesyl pyrophosphateRattus norvegicus (Norway rat)Ki2.600011
omapatrilatRattus norvegicus (Norway rat)Ki10.000011
squalestatin 1Rattus norvegicus (Norway rat)IC500.006222
3-(biphenyl-4-yl)-3-hydroxyquinuclidineRattus norvegicus (Norway rat)IC500.040024
zaragozic acid bRattus norvegicus (Norway rat)IC500.000211
zaragozic acid cRattus norvegicus (Norway rat)IC500.000411

Drugs with Other Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
farnesyl pyrophosphateRattus norvegicus (Norway rat)Km12.700011