Page last updated: 2024-08-01 09:08:05
6-ketoprostaglandin f1 alpha
Description
6-Ketoprostaglandin F1 alpha: The physiologically active and stable hydrolysis product of EPOPROSTENOL. Found in nearly all mammalian tissue. [MeSH]
6-oxoprostaglandin F1alpha : A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position. [CHeBI]
Cross-References
Synonyms (64)
| Synonym |
|---|
| CHEBI:28158 , |
| 6-ketoprostaglandin f1alpha |
| 6-oxoprostaglandin f1alpha |
| (13e,15s)-9alpha,11alpha,15-trihydroxy-6-oxoprost-13-en-1-oic acid |
| MLS000028869 |
| 6-keto prostaglandin f1alpha |
| smr000058896 |
| SMP2_000282 |
| LMFA03010001 |
| 6-oxo-pgf1alpha |
| 6-oxo-prostaglandin f1alpha |
| 6-oxo-9s,11r,15s-trihydroxy-13e-prostenoic acid |
| BSPBIO_001457 |
| IDI1_033927 |
| 6-keto-pgf1a |
| 58962-34-8 |
| 6-keto-prostaglandin f1a |
| C05961 |
| 6-keto-pgf1alpha |
| 6-keto-prostaglandin f1alpha |
| NCGC00161289-02 |
| NCGC00161289-01 |
| NCGC00161289-03 |
| prost-13-en-1-oic acid, 9,11,15-trihydroxy-6-oxo-, (9alpha,11alpha,13e,15s)- |
| 6-ketoprostaglandin f1 alpha |
| prostaglandin f1a, 6-oxo- |
| DE7EA974-152E-4B77-88BF-F809636EB050 |
| HMS1989I19 |
| BML1-G02 |
| HMS1791I19 |
| HMS1361I19 |
| SCHEMBL4343736 |
| 7-[(1r,2r,3r,5s)-3,5-dihydroxy-2-[(e,3s)-3-hydroxyoct-1-enyl]cyclopentyl]-6-oxoheptanoic acid |
| pgf1 alpha 6-keto |
| bdbm82211 |
| cas_58962-34-8 |
| prosta-13-en-1-oic acid, 9,11,15-trihydroxy-6-oxo-, (9alpha,11alpha,13e,15s)- |
| unii-8urb805jjj |
| 8urb805jjj , |
| 6-keto-prostaglandin f1-alpha |
| 6-ketoprostaglandin f1|a |
| CHEMBL2074840 |
| KFGOFTHODYBSGM-ZUNNJUQCSA-N |
| 6-keto pgf1alpha |
| 6-keto-pgf1.alpha. |
| 6-oxo-pgf1.alpha. |
| prost-13-en-1-oic acid, 9,11,15-trihydroxy-6-oxo-, (9.alpha.,11.alpha.,13e,15s)- |
| 6-ketoprostaglandin f1.alpha. |
| HMS3402I19 |
| HMS3648L05 |
| 6-oxoprostaglandin f1a |
| 6-oxo-9s,11r,15s-trihydroxy-13e-prostenoate |
| 6-oxo-pgf1a |
| 7-((1r,2r,3r,5s)-3,5-dihydroxy-2-((s,e)-3-hydroxyoct-1-enyl)cyclopentyl)-6-oxoheptanoic acid |
| Q27103534 |
| SR-01000946444-1 |
| sr-01000946444 |
| 6-keto-prostaglandin f1 alpha |
| 6-oxo-9alpha,11alpha,15s-trihydroxy-prost-13e-en-1-oic acid |
| DTXSID001317937 |
| PD020580 |
| CS-0062290 |
| 6-keto prostaglandin f1|a |
| HY-113358 |
Roles (2)
| Role | Description |
|---|
| human metabolite | Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). |
| mouse metabolite | Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). |
Drug Classes (1)
Pathways (48)
6-ketoprostaglandin f1 alpha is involved in 48 pathway(s), involving a total of 3374 unique proteins and 4799 unique compounds
Protein Targets (1)
Other Measurements
Bioassays (5)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
ISSN: 1091-6490 | Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
ISSN: 2211-1247 | A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
ISSN: 1872-9096 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
ISSN: 1464-3405 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID681576 | TP_TRANSPORTER: uptake in PGT-expressing HeLa cells | 1995 | Science (New York, N.Y.), May-12, Volume: 268, Issue:5212
ISSN: 0036-8075 | Identification and characterization of a prostaglandin transporter. |
Research
Studies (4,651)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 2277 (48.96) | 18.7374 |
| 1990's | 1693 (36.40) | 18.2507 |
| 2000's | 509 (10.94) | 29.6817 |
| 2010's | 158 (3.40) | 24.3611 |
| 2020's | 14 (0.30) | 2.80 |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 294 (6.08%) | 5.53% |
| Reviews | 31 (0.64%) | 6.00% |
| Case Studies | 20 (0.41%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 4,487 (92.86%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|
| acetylcarnitine | | O-acylcarnitine | human metabolite | 1990 | 1996 | 30.7 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| 2-oxo-3-methylvalerate | | 2-oxo monocarboxylic acid;
branched-chain keto acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| alpha-ketoisovalerate | | 2-oxo monocarboxylic acid;
branched-chain keto acid | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2,3-diphosphoglycerate | | bisphosphoglyceric acid;
tetronic acid derivative | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-keto-4-methylvalerate | | 2-oxo monocarboxylic acid;
branched-chain keto acid | algal metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxyanthranilic acid | | aminobenzoic acid;
monohydroxybenzoic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxykynurenine | | hydroxykynurenine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-oxoadipic acid | | dicarboxylic fatty acid;
oxo dicarboxylic acid | bacterial xenobiotic metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-mercaptopyruvic acid | | 2-oxo monocarboxylic acid;
thiol | antidote to cyanide poisoning;
Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphoserine | | non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
serine derivative | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-phenylpropionic acid | | benzenes;
monocarboxylic acid | antifungal agent;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-aminobutyric acid | | amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid | human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-hydroxyphenylacetic acid | | monocarboxylic acid;
phenols | fungal metabolite;
human metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isocaproaldehyde | | alpha-CH2-containing aldehyde | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aminolevulinic acid | | 4-oxo monocarboxylic acid;
amino acid zwitterion;
delta-amino acid | antineoplastic agent;
dermatologic drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite;
prodrug;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-aminovaleric acid | | amino acid zwitterion;
delta-amino acid;
omega-amino fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxytryptophan | | hydroxytryptophan | human metabolite;
neurotransmitter | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acetaldehyde | | aldehyde | carcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent | 1987 | 1993 | 35.5 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| acetone | | ketone body;
methyl ketone;
propanones;
volatile organic compound | EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acetyl phosphate | | acyl monophosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adenine | | 6-aminopurines;
purine nucleobase | Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1987 | 1989 | 36.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| allantoin | | imidazolidine-2,4-dione;
ureas | Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite;
vulnerary | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| anthranilic acid | | aminobenzoic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta-alanine | | amino acid zwitterion;
beta-amino acid | agonist;
fundamental metabolite;
human metabolite;
inhibitor;
neurotransmitter | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| betaine aldehyde | | quaternary ammonium ion | Aspergillus metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-butanol | | alkyl alcohol;
primary alcohol;
short-chain primary fatty alcohol | human metabolite;
mouse metabolite;
protic solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ureidosuccinic acid | | aspartic acid derivative;
C4-dicarboxylic acid;
N-carbamoyl-amino acid | Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| carbon monoxide | | carbon oxide;
gas molecular entity;
one-carbon compound | biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent | 1987 | 2008 | 29.0 | low | 0 | 2 | 1 | 1 | 0 | 0 |
| carnitine | | amino-acid betaine | human metabolite;
mouse metabolite | 1990 | 1994 | 32.3 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| choline | | cholines | allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| chlorine | | halide anion;
monoatomic chlorine | cofactor;
Escherichia coli metabolite;
human metabolite | 1983 | 2014 | 29.4 | low | 3 | 6 | 7 | 2 | 1 | 0 |
| coumarin | | coumarins | fluorescent dye;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aminoethylphosphonic acid | | phosphonic acids;
primary amino compound;
zwitterion | human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| octanoic acid | | medium-chain fatty acid;
straight-chain saturated fatty acid | antibacterial agent;
Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydrolipoic acid | | thio-fatty acid | antioxidant;
human metabolite;
neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trimethylenediamine | | alkane-alpha,omega-diamine | human metabolite;
mouse metabolite;
reagent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxybutyric acid | | (omega-1)-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
hydroxybutyric acid | human metabolite | 1996 | 1996 | 28.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| methylmalonic acid | | C4-dicarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyrrolidonecarboxylic acid | | oxoproline;
pyrrolidin-2-ones;
pyrrolidinemonocarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,4-dihydroxyphenylacetic acid | | catechols;
dihydroxyphenylacetic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| alpha-keto-delta-guanidinovaleric acid | | 2-oxo monocarboxylic acid;
zwitterion | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| creatine | | glycine derivative;
guanidines;
zwitterion | geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent;
nutraceutical | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cytosine | | aminopyrimidine;
pyrimidine nucleobase;
pyrimidone | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydrouracil | | pyrimidone | Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydrolipoamide | | dithiol;
monocarboxylic acid amide | cofactor;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydroxyacetone phosphate | | glycerone phosphates;
primary alpha-hydroxy ketone | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydroxyacetone | | ketotriose;
primary alpha-hydroxy ketone | antifungal agent;
Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dimethylglycine | | amino acid zwitterion;
N-methyl-amino acid;
N-methylglycines | Daphnia magna metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5,6-dimethylbenzimidazole | | dimethylbenzimidazole | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ethanolamine | | ethanolamines;
primary alcohol;
primary amine | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-butyrobetaine | | amino-acid betaine | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glutaric acid | | alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid | Daphnia magna metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycerol | | alditol;
triol | algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent | 1981 | 1993 | 37.6 | low | 0 | 6 | 1 | 0 | 0 | 0 |
| alpha-glycerophosphoric acid | | glycerol monophosphate | algal metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycolaldehyde | | glycolaldehydes | fundamental metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glyoxylic acid | | 2-oxo monocarboxylic acid;
aldehydic acid | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycocyamine | | guanidinoacetic acids;
zwitterion | bacterial metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydrogen cyanide | | hydracid;
one-carbon compound | Escherichia coli metabolite;
human metabolite;
poison | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydrogen carbonate | | carbon oxoanion | cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1984 | 1994 | 35.9 | low | 0 | 6 | 2 | 0 | 0 | 0 |
| histamine | | aralkylamino compound;
imidazoles | human metabolite;
mouse metabolite;
neurotransmitter | 1981 | 2013 | 33.8 | low | 1 | 27 | 16 | 4 | 1 | 0 |
| homogentisic acid | | dihydroxyphenylacetic acid;
hydroquinones | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydrogen | | elemental hydrogen;
elemental molecule;
gas molecular entity | antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| indole-3-acetaldehyde | | indoleacetaldehyde | bacterial metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| indoleacetic acid | | indole-3-acetic acids;
monocarboxylic acid | auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| itaconic acid | | dicarboxylic acid;
dicarboxylic fatty acid;
olefinic compound | fungal metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| potassium | | alkali metal cation;
elemental potassium;
monoatomic monocation;
monovalent inorganic cation | cofactor;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydroxyphenylalanine | | hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| kynurenine | | aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lipoamide | | dithiolanes;
monocarboxylic acid amide | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| malonic acid | | alpha,omega-dicarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| methylmercaptan | | alkanethiol | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyruvaldehyde | | 2-oxo aldehyde;
propanals | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| methanol | | alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound | amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| melatonin | | acetamides;
tryptamines | anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger | 1986 | 2006 | 28.0 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| n-acetylserotonin | | acetamides;
N-acylserotonin;
phenols | antioxidant;
human metabolite;
mouse metabolite;
tropomyosin-related kinase B receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-methylphenylethanolamine | | alkaloid;
phenylethanolamines | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n'-acetylspermine | | acetamides;
acetylspermine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nitrites | | monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species | human metabolite | 1994 | 2018 | 21.8 | low | 3 | 0 | 15 | 17 | 3 | 0 |
| hydroxypyruvic acid | | 2-oxo monocarboxylic acid;
3-hydroxy monocarboxylic acid;
primary alpha-hydroxy ketone | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| oxalic acid | | alpha,omega-dicarboxylic acid | algal metabolite;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-hydroxyphenylpyruvic acid | | 2-oxo monocarboxylic acid;
phenols | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hexadecanal | | 2,3-saturated fatty aldehyde;
long-chain fatty aldehyde | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenylacetaldehyde | | alpha-CH2-containing aldehyde;
phenylacetaldehydes | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenylacetic acid | | benzenes;
monocarboxylic acid;
phenylacetic acids | allergen;
Aspergillus metabolite;
auxin;
EC 6.4.1.1 (pyruvate carboxylase) inhibitor;
Escherichia coli metabolite;
human metabolite;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite;
toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxyphenethylamine | | phenylethanolamines | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenethylamine | | alkaloid;
aralkylamine;
phenylethylamine | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphoric acid | | phosphoric acids | algal metabolite;
fertilizer;
human metabolite;
NMR chemical shift reference compound;
solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphorylcholine | | phosphocholines | allergen;
epitope;
hapten;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphorylethanolamine | | phosphoethanolamine;
primary amino compound | algal metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| picolinic acid | | pyridinemonocarboxylic acid | human metabolite;
MALDI matrix material | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyridoxal | | hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 | cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyridoxal phosphate | | methylpyridines;
monohydroxypyridine;
pyridinecarbaldehyde;
vitamin B6 phosphate | coenzyme;
cofactor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyridoxamine | | aminoalkylpyridine;
hydroxymethylpyridine;
monohydroxypyridine;
vitamin B6 | Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyridoxamine phosphate | | aminoalkylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6 phosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyridoxine | | hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6 | cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| quinolinic acid | | pyridinedicarboxylic acid | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thiosulfates | | divalent inorganic anion;
sulfur oxide;
sulfur oxoanion | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sarcosine | | N-alkylglycine zwitterion;
N-alkylglycine;
N-methyl-amino acid;
N-methylglycines | Escherichia coli metabolite;
glycine receptor agonist;
glycine transporter 1 inhibitor;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| taurine | | amino sulfonic acid;
zwitterion | antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite | 1987 | 1998 | 31.8 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| thiamine | | primary alcohol;
vitamin B1 | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thymine | | pyrimidine nucleobase;
pyrimidone | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-(4-methyl-1,3-thiazol-5-yl)ethanol | | 1,3-thiazoles;
primary alcohol | Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tryptamine | | aminoalkylindole;
aralkylamino compound;
indole alkaloid;
tryptamines | human metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uracil | | pyrimidine nucleobase;
pyrimidone | allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prodrug;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uric acid | | uric acid | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 1983 | 2008 | 31.4 | low | 2 | 3 | 3 | 1 | 0 | 0 |
| urea | | isourea;
monocarboxylic acid amide;
one-carbon compound | Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1993 | 1998 | 28.3 | low | 1 | 0 | 3 | 0 | 0 | 0 |
| vanilmandelic acid | | 2-hydroxy monocarboxylic acid;
aromatic ether;
phenols | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| perillic acid | | alpha,beta-unsaturated monocarboxylic acid;
cyclohexenecarboxylic acid | antineoplastic agent;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| meglutol | | 3-hydroxy carboxylic acid;
dicarboxylic acid;
tertiary alcohol | anticholesteremic drug;
antimetabolite;
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| homovanillic acid | | guaiacols;
monocarboxylic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxy-4-methoxyphenethylamine | | monomethoxybenzene;
phenols;
phenylethylamine;
primary amino compound | human metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydroxyindoleacetic acid | | indole-3-acetic acids | drug metabolite;
human metabolite;
mouse metabolite | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 5-methoxytryptamine | | aromatic ether;
primary amino compound;
tryptamines | 5-hydroxytryptamine 2A receptor agonist;
5-hydroxytryptamine 2B receptor agonist;
5-hydroxytryptamine 2C receptor agonist;
antioxidant;
cardioprotective agent;
human metabolite;
mouse metabolite;
neuroprotective agent;
radiation protective agent;
serotonergic agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cetyl alcohol | | hexadecanol;
long-chain primary fatty alcohol | algal metabolite;
flavouring agent;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-cresol | | cresol | Escherichia coli metabolite;
human metabolite;
uremic toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| debrisoquin | | carboxamidine;
isoquinolines | adrenergic agent;
antihypertensive agent;
human metabolite;
sympatholytic agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| decanoic acid | | medium-chain fatty acid;
straight-chain saturated fatty acid | algal metabolite;
anti-inflammatory agent;
antibacterial agent;
human metabolite;
plant metabolite;
volatile oil component | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nordazepam | | 1,4-benzodiazepinone;
organochlorine compound | anticonvulsant;
anxiolytic drug;
GABA modulator;
human metabolite;
sedative | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2,5-dihydroxybenzoic acid | | dihydroxybenzoic acid | EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
fungal metabolite;
human metabolite;
MALDI matrix material;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tele-methylhistamine | | imidazoles;
primary amino compound | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| indolepropionic acid | | indol-3-yl carboxylic acid | auxin;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| kynurenic acid | | monohydroxyquinoline;
quinolinemonocarboxylic acid | G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-phenyllactic acid | | 2-hydroxy monocarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-amino-3-phosphonopropionic acid | | alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids | human metabolite;
metabotropic glutamate receptor antagonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-phenylglycine | | non-proteinogenic alpha-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nifedipine | | C-nitro compound;
dihydropyridine;
methyl ester | calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent | 1982 | 2004 | 33.0 | low | 3 | 11 | 14 | 2 | 0 | 0 |
| oxidopamine | | benzenetriol;
catecholamine;
primary amino compound | drug metabolite;
human metabolite;
neurotoxin | 1985 | 1992 | 35.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| sebacic acid | | alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| stearic acid | | long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| succinylacetone | | beta-diketone;
dioxo monocarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tolbutamide | | N-sulfonylurea | human metabolite;
hypoglycemic agent;
insulin secretagogue;
potassium channel blocker | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| retinoic acid | | alpha,beta-unsaturated monocarboxylic acid;
retinoid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tyramine | | monoamine molecular messenger;
primary amino compound;
tyramines | EC 3.1.1.8 (cholinesterase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| corticosterone | | 11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 1979 | 2017 | 31.5 | low | 0 | 4 | 5 | 0 | 1 | 0 |
| estriol | | 16alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid | estrogen;
human metabolite;
human xenobiotic metabolite;
mouse metabolite | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sorbitol | | glucitol | cathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent | 1989 | 1997 | 30.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| thymidine | | pyrimidine 2'-deoxyribonucleoside | Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite | 1987 | 1998 | 31.2 | low | 0 | 2 | 4 | 0 | 0 | 0 |
| hydroxyproline | | 4-hydroxyproline;
L-alpha-amino acid zwitterion | human metabolite;
mouse metabolite;
plant metabolite | 1983 | 1996 | 36.8 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| thyroxine | | 2-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine | antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone | 1985 | 1998 | 34.2 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| aldosterone | | 11beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde | human metabolite;
mouse metabolite | 1983 | 2014 | 32.8 | low | 10 | 29 | 15 | 3 | 2 | 0 |
| cysteine | | cysteine zwitterion;
cysteine;
L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid | EC 4.3.1.3 (histidine ammonia-lyase) inhibitor;
flour treatment agent;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| estrone | | 17-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols | antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite | 1981 | 1992 | 38.5 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| androsterone | | 17-oxo steroid;
3alpha-hydroxy steroid;
androstanoid;
C19-steroid | androgen;
anticonvulsant;
human blood serum metabolite;
human metabolite;
human urinary metabolite;
mouse metabolite;
pheromone | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| etiocholanolone | | 17-oxo steroid;
3alpha-hydroxy steroid;
androstanoid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dehydroepiandrosterone | | 17-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid | androgen;
human metabolite;
mouse metabolite | 1984 | 1995 | 34.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| triiodothyronine | | 2-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine | human metabolite;
mouse metabolite;
thyroid hormone | 1985 | 1998 | 33.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| isonicotinic acid | | pyridinemonocarboxylic acid | algal metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| serine | | L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| glutamine | | amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 2001 | 2009 | 19.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| lysine | | aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid | algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1985 | 1998 | 33.0 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| sucrose | | glycosyl glycoside | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent | 1981 | 2002 | 32.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| adenosine diphosphate | | adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate | fundamental metabolite;
human metabolite | 1980 | 2013 | 32.3 | low | 6 | 28 | 21 | 6 | 3 | 0 |
| uridine | | uridines | drug metabolite;
fundamental metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uridine monophosphate | | pyrimidine ribonucleoside 5'-monophosphate;
uridine 5'-phosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| levodopa | | amino acid zwitterion;
dopa;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid | allelochemical;
antidyskinesia agent;
antiparkinson drug;
dopaminergic agent;
hapten;
human metabolite;
mouse metabolite;
neurotoxin;
plant growth retardant;
plant metabolite;
prodrug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cysteamine | | amine;
thiol | geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent | 1986 | 1993 | 35.2 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| leucine | | amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1993 | 1997 | 28.7 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| androstenedione | | 17-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid | androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite | 1985 | 1990 | 35.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| cytidine monophosphate | | cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-monophosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| methionine | | aspartate family amino acid;
L-alpha-amino acid;
methionine zwitterion;
methionine;
proteinogenic amino acid | antidote to paracetamol poisoning;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| desoxycorticosterone | | 20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
mineralocorticoid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 1985 | 1998 | 33.3 | low | 0 | 3 | 3 | 0 | 0 | 0 |
| cytidine | | cytidines | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 17-alpha-hydroxyprogesterone | | 17alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
tertiary alpha-hydroxy ketone | human metabolite;
metabolite;
mouse metabolite;
progestin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| asparagine | | amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| histidine | | amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-pentanol | | pentanol;
short-chain primary fatty alcohol | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| valine | | L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| threonine | | amino acid zwitterion;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
threonine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tryptophan | | erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan | antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1981 | 2004 | 28.4 | low | 0 | 1 | 3 | 1 | 0 | 0 |
| isoleucine | | aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ethylamine | | primary aliphatic amine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| taurocholic acid | | amino sulfonic acid;
bile acid taurine conjugate | human metabolite | 1984 | 2009 | 30.5 | low | 0 | 5 | 7 | 2 | 0 | 0 |
| skatole | | methylindole | human metabolite;
mammalian metabolite | 1989 | 1993 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| quinaldic acid | | quinolinemonocarboxylic acid | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-methylpentane | | alkane;
volatile organic compound | allelochemical;
human metabolite;
non-polar solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| methylcyclopentane | | cycloalkane;
volatile organic compound | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphoribosyl pyrophosphate | | 5-O-phosphono-D-ribofuranosyl diphosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-phenethylamine | | phenylethylamine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trehalose | | trehalose | Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isethionic acid | | alkanesulfonic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| methylcyclohexane | | cycloalkane;
volatile organic compound | aprotic solvent;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| piperidine | | azacycloalkane;
piperidines;
saturated organic heteromonocyclic parent;
secondary amine | base;
catalyst;
human metabolite;
non-polar solvent;
plant metabolite;
protic solvent;
reagent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| undecanoic acid | | medium-chain fatty acid;
straight-chain saturated fatty acid | antifungal agent;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-tridecanol | | long-chain primary fatty alcohol;
tridecanol | bacterial metabolite;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| stearyl alcohol | | long-chain primary fatty alcohol;
octadecanol | algal metabolite;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acetol | | methyl ketone;
primary alcohol;
primary alpha-hydroxy ketone;
propanones | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-methylbutanoic acid | | methylbutyric acid | bacterial metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hexanoic acid | | medium-chain fatty acid;
straight-chain saturated fatty acid | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isopropyl palmitate | | fatty acid ester;
isopropyl ester | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pregnenolone | | 20-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
C21-steroid | human metabolite;
mouse metabolite | 1983 | 1993 | 36.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| 20-alpha-dihydroprogesterone | | 20-hydroxypregn-4-en-3-one | human metabolite;
mouse metabolite | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| homoarginine | | homoarginine;
L-lysine derivative;
non-proteinogenic L-alpha-amino acid | biomarker;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
human metabolite;
rat metabolite;
xenobiotic metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dibenzo(a,l)pyrene | | ortho- and peri-fused polycyclic arene | human metabolite;
mutagen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| diiodotyrosine | | diiodotyrosine;
L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-methoxytyrosine | | aromatic L-alpha-amino acid zwitterion;
L-tyrosine derivative;
monomethoxybenzene;
non-proteinogenic L-alpha-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thiocyanate | | pseudohalide anion;
sulfur molecular entity | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-hydroxyphenyllactic acid | | 2-hydroxy carboxylic acid;
phenols | bacterial metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| citrulline | | amino acid zwitterion;
citrulline | Daphnia magna metabolite;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
protective agent;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lithocholic acid | | bile acid;
C24-steroid;
monohydroxy-5beta-cholanic acid | geroprotector;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nandrolone | | 17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
anabolic androgenic steroid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-methylcatechol | | methylcatechol | antioxidant;
carcinogenic agent;
hapten;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| homocystine | | amino acid zwitterion;
homocystines | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| chenodeoxycholic acid | | bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycocholic acid | | bile acid glycine conjugate | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| epitestosterone | | 17alpha-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid | androgen antagonist;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ninhydrin | | aromatic ketone;
beta-diketone;
indanones;
ketone hydrate | colour indicator;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| indican | | aryl sulfate;
indoles | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| suberic acid | | alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hexadecanedioic acid | | alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| androstenediol | | 17beta-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid | androgen;
human metabolite;
mouse metabolite;
radiation protective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydrotestosterone | | 17beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid | androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| pyridoxamine dihydrochloride | | hydrochloride;
vitamin B6 | Escherichia coli metabolite;
human metabolite;
iron chelator;
mouse metabolite;
nephroprotective agent;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aceturic acid | | N-acetyl-amino acid;
N-acylglycine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| myristic acid | | long-chain fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite | 1989 | 1993 | 33.0 | low | 1 | 1 | 1 | 0 | 0 | 0 |
| glycylglycine | | dipeptide zwitterion;
dipeptide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lignoceric acid | | straight-chain saturated fatty acid;
very long-chain fatty acid | Daphnia tenebrosa metabolite;
human metabolite;
plant metabolite;
volatile oil component | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 18-hydroxycorticosterone | | 11beta-hydroxy steroid;
18-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo steroid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxybutyric acid | | 2-hydroxy monocarboxylic acid;
hydroxybutyric acid | algal metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-methylhexane | | alkane;
volatile organic compound | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ethylmalonic acid | | dicarboxylic acid;
dicarboxylic fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| galactitol | | hexitol | Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxyphenylacetic acid | | hydroxy monocarboxylic acid;
phenols | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acetylcysteine | | acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid | antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-methyl-2-furfural | | aldehyde;
furans | EC 2.2.1.6 (acetolactate synthase) inhibitor;
flavouring agent;
human metabolite;
Maillard reaction product | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hexanol | | hexanol;
secondary alcohol | human metabolite;
plant metabolite;
semiochemical | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,1,3,3-tetramethylurea | | ureas | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycochenodeoxycholic acid | | bile acid glycine conjugate | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isocaproic acid | | branched-chain saturated fatty acid;
medium-chain fatty acid;
methyl-branched fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dehydroepiandrosterone sulfate | | 17-oxo steroid;
steroid sulfate | EC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite;
mouse metabolite | 1984 | 1995 | 34.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| homoserine | | amino acid zwitterion;
homoserine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dodecanedioic acid | | alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid | EC 1.1.1.1 (alcohol dehydrogenase) inhibitor;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxycytidine | | pyrimidine 2'-deoxyribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxyuridine | | pyrimidine 2'-deoxyribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2'-deoxyadenosine | | purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cytidine diphosphate choline | | nucleotide-(amino alcohol)s;
phosphocholines | human metabolite;
mouse metabolite;
neuroprotective agent;
psychotropic drug;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-pentene-3-one | | enone | flavouring agent;
genotoxin;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 alpha-androstane-3 alpha,17 beta-diol | | androstane-3alpha,17beta-diol | Daphnia magna metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 9,10-epoxystearic acid | | epoxystearic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxyindole | | hydroxyindoles | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta-hydroxymyristic acid | | 3-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
long-chain fatty acid | bacterial metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| perillaldehyde | | aldehyde;
olefinic compound | human metabolite;
mouse metabolite;
volatile oil component | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tricosanoic acid | | straight-chain saturated fatty acid;
very long-chain fatty acid | Daphnia magna metabolite;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uridine diphosphate glucuronic acid | | UDP-D-glucuronic acid | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tetrahydropapaveroline | | benzylisoquinoline alkaloid;
benzyltetrahydroisoquinoline;
isoquinolinol | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dithiothreitol | | 1,4-dimercaptobutane-2,3-diol;
butanediols;
dithiol;
glycol;
thiol | chelator;
human metabolite;
reducing agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cyclic cmp | | 3',5'-cyclic pyrimidine nucleotide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| furoylglycine | | furans;
N-acylglycine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,3',5'-triiodothyronine | | iodothyronine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| limonene | | cycloalkene;
p-menthadiene | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hypochlorous acid | | chlorine oxoacid;
reactive oxygen species | EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| urobilinogen | | bilanes | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| estetrol | | 15alpha-hydroxy steroid;
16alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid;
steroid hormone | estrogen receptor agonist;
estrogen;
human metabolite;
human xenobiotic metabolite;
oral contraceptive | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| iron | | divalent metal cation;
iron cation;
monoatomic dication | cofactor;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-methyladenosine | | methyladenosine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| iodine | | halide anion;
monoatomic iodine | human metabolite | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| nonanal | | medium-chain fatty aldehyde;
n-alkanal;
saturated fatty aldehyde | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dimethylacetamide | | acetamides;
monocarboxylic acid amide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ursodeoxycholic acid | | bile acid;
C24-steroid;
dihydroxy-5beta-cholanic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pregnanolone | | 3-hydroxy-5beta-pregnan-20-one;
3alpha-hydroxy steroid | human metabolite;
intravenous anaesthetic;
sedative | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| s-adenosylmethionine | | sulfonium betaine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acetylgalactosamine | | N-acetyl-D-hexosamine;
N-acetylgalactosamine | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| paclitaxel | | taxane diterpenoid;
tetracyclic diterpenoid | antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| norsalsolinol | | isoquinolinol | animal metabolite;
apoptosis inducer;
human metabolite;
marine metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline | | isoquinolinol;
tertiary amino compound | human metabolite;
neurotoxin;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adenosine | | adenosines;
purines D-ribonucleoside | analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent | 1983 | 2014 | 31.1 | low | 3 | 8 | 10 | 3 | 1 | 0 |
| d-lactic acid | | 2-hydroxypropanoic acid | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| xanthosine | | purines D-ribonucleoside;
xanthosines | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,5-anhydroglucitol | | anhydro sugar | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-methylhistidine | | L-histidine derivative;
non-proteinogenic L-alpha-amino acid;
zwitterion | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-methylcytosine | | methylcytosine;
pyrimidines | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylaspartic acid | | N-acetyl-L-amino acid;
N-acyl-L-aspartic acid | antioxidant;
human metabolite;
mouse metabolite;
nutraceutical;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxyuridine triphosphate | | deoxyuridine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-triphosphate | Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| homocitrulline | | amino acid zwitterion;
L-lysine derivative;
non-proteinogenic L-alpha-amino acid;
ureas | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholesteryl sulfate | | steroid sulfate | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2'-deoxycytidine 5'-triphosphate | | 2'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-triphosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 25-hydroxycholesterol | | 25-hydroxy steroid;
oxysterol | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aica ribonucleotide | | 1-(phosphoribosyl)imidazolecarboxamide;
aminoimidazole | cardiovascular drug;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylserine | | acetyl-L-serine;
N-acetyl-L-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| o-4-methylthymine | | aromatic ether;
methylthymine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tetraiodothyroacetic acid | | 2-halophenol;
aromatic ether;
iodophenol;
monocarboxylic acid | apoptosis inducer;
human metabolite;
thyroid hormone | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lathosterol | | 3beta-sterol;
C27-steroid;
cholestanoid;
Delta(7)-sterol | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| omega-aminocaprylic acid | | medium-chain fatty acid;
omega-amino fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-methoxyestradiol | | 17beta-hydroxy steroid;
3-hydroxy steroid | angiogenesis modulating agent;
antimitotic;
antineoplastic agent;
human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| parabanic acid | | hydracid;
imidazolidinone | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetyl-l-arginine | | N-acetyl-L-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cystine | | cystine zwitterion;
cystine;
L-cysteine derivative;
non-proteinogenic L-alpha-amino acid | EC 1.2.1.11 (aspartate-semialdehyde dehydrogenase) inhibitor;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 6-methyladenine | | 6-alkylaminopurine;
methyladenine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenylacetylglycine | | monocarboxylic acid amide;
monocarboxylic acid;
N-acylglycine | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydracrylic acid | | 3-hydroxy monocarboxylic acid;
omega-hydroxy-short-chain fatty acid | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hordenine | | phenethylamine alkaloid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-methoxyestradiol | | 17beta-hydroxy steroid;
3-hydroxy steroid;
aromatic ether;
phenols | estrogen;
human metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glutaurine | | dipeptide zwitterion;
dipeptide;
L-glutamine derivative;
sulfonic acid | anticonvulsant;
anxiolytic drug;
hormone;
human metabolite;
mammalian metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| plasmenylserine | | O-phosphoserine | EC 1.4.7.1 [glutamate synthase (ferredoxin)] inhibitor;
EC 2.5.1.49 (O-acetylhomoserine aminocarboxypropyltransferase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ubiquinone-o | | ubiquinones | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta-hydroxyisovaleric acid | | 3-hydroxy monocarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylhistamine | | acetamides;
imidazoles | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| indole-3-carboxylic acid | | indol-3-yl carboxylic acid | bacterial metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxymethylcytosine | | aminopyrimidine;
aromatic primary alcohol;
nucleobase analogue;
pyrimidone | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylglutamic acid | | N-acetyl-L-amino acid;
N-acyl-L-glutamic acid | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2,5-dihydroxybenzaldehyde | | dihydroxybenzaldehyde | human metabolite;
mouse metabolite;
Penicillium metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| D-serine | | D-alpha-amino acid;
serine zwitterion;
serine | Escherichia coli metabolite;
human metabolite;
NMDA receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| D-alanine | | alanine zwitterion;
alanine;
D-alpha-amino acid | EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-ketopentanoic acid | | 2-oxo monocarboxylic acid;
oxopentanoic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydroxyindoleacetaldehyde | | hydroxyindoles;
indoleacetaldehyde | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| leucylleucine | | dipeptide;
L-aminoacyl-L-amino acid zwitterion | human metabolite;
Mycoplasma genitalium metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxymethyluracil | | primary alcohol;
pyrimidone | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 12-hydroxydodecanoic acid | | omega-hydroxy-medium-chain fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| decane-1,2-diol | | glycol;
volatile organic compound | anti-inflammatory agent;
antioxidant;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-nitrophenyl sulfate | | aryl sulfate;
C-nitro compound | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glucose-1,6-bisphosphate | | D-glucose 1,6-bisphosphate | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| biotinamide | | biotins;
monocarboxylic acid amide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,4-dihydroxymandelic acid | | 2-hydroxy monocarboxylic acid;
catechols | antioxidant;
drug metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxymandelic acid | | 2-hydroxy monocarboxylic acid;
phenols | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylalanine | | L-alanine derivative;
N-acetyl-L-amino acid | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 17-alpha-hydroxypregnenolone | | 17alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
hydroxypregnenolone;
tertiary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 1980 | 1980 | 44.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cholest-4-en-3-one | | 3-oxo-Delta(4) steroid;
cholestanoid | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| mephentermine | | 2-aminooctadecane-1,3-diol | EC 2.7.11.13 (protein kinase C) inhibitor;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-pinene oxide | | epoxide;
pinane monoterpenoid | bacterial xenobiotic metabolite;
fragrance;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-methylhistidine | | L-histidine derivative;
non-proteinogenic L-alpha-amino acid;
zwitterion | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxybutyric acid | | 3-hydroxybutyric acid;
ketone body | fungal metabolite;
human metabolite;
pheromone | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| L-2-aminoadipic acid | | 2-aminoadipic acid | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| testosterone acetate | | 3-oxo-Delta(4) steroid;
androstanoid;
sterol ester | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenylacetylglutamine | | N(2)-phenylacetylglutamine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5beta-pregnane-3,20-dione | | 20-oxo steroid;
3-oxo-5beta-steroid;
C21-steroid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| zymosterol | | 3beta-sterol;
cholestanoid | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| brexanolone | | 3-hydroxy-5alpha-pregnan-20-one | antidepressant;
GABA modulator;
human metabolite;
intravenous anaesthetic;
sedative | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-alpha-dihydroprogesterone | | 20-oxo steroid;
3-oxo-5alpha-steroid;
C21-steroid hormone | human metabolite;
progestogen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-epsilon-acetyllysine | | acetyl-L-lysine;
amino acid zwitterion;
N(6)-acyl-L-lysine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxyhexadecanoic acid | | 2-hydroxy fatty acid;
hydroxypalmitic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 19-oxo-delta(4) androstene-3,17-dione | | 17-oxo steroid;
19-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid;
steroid aldehyde | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-glutamylglutamate | | dipeptide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| indole-3-lactic acid | | hydroxy monocarboxylic acid;
indol-3-yl carboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n(alpha)-acetyllysine | | acetyl-L-lysine;
amino acid zwitterion | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycyl-l-phenylalanine | | dipeptide zwitterion;
dipeptide | human metabolite;
metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5,6-dihydrothymine | | pyrimidone | human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-glutamyltyrosine | | dicarboxylic acid;
dipeptide;
phenols;
primary amino compound;
secondary carboxamide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholest-5-ene-3 beta,26-diol | | 26-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol | EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxyisovaleric acid | | 2-hydroxy monocarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aminomalonic acid | | amino dicarboxylic acid | Daphnia magna metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| zymostenol | | 3beta-sterol;
cholestanoid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 16-hydroxydehydroepiandrosterone | | 16alpha-hydroxy steroid;
17-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid;
secondary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cortisol 21-sulfate | | 11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
cortisol ester;
steroid sulfate;
tertiary alpha-hydroxy ketone | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,2-distearoylphosphatidylethanolamine | | phosphatidylethanolamine zwitterion;
phosphatidylethanolamine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydrogen sulfite | | sulfur oxoanion | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aflatoxin b1-2,3-oxide | | aflatoxin | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| fructose 2,6-diphosphate | | D-fructofuranose 2,6-bisphosphate | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pregnenolone sulfate | | steroid sulfate | EC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,3'-diiodothyronine | | 3,3'-diiodothyronine;
amino acid zwitterion | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| l-lactic acid | | (2S)-2-hydroxy monocarboxylic acid;
2-hydroxypropanoic acid | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| propionylcarnitine | | O-acylcarnitine | analgesic;
antirheumatic drug;
cardiotonic drug;
human metabolite;
peripheral nervous system drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hypotaurine | | aminosulfinic acid;
zwitterion | human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| testosterone 17-glucosiduronate | | 3-oxo steroid;
beta-D-glucosiduronic acid;
enone;
steroid glucosiduronic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-chloro-L-tyrosine | | chloroamino acid;
L-alpha-amino acid zwitterion;
L-tyrosine derivative;
monochlorobenzenes;
non-proteinogenic L-alpha-amino acid | biomarker;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| androsterone glucuronide | | beta-D-glucosiduronic acid;
steroid glucosiduronic acid | human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| selenomethylselenocysteine | | non-proteinogenic alpha-amino acid;
selenocysteines | antineoplastic agent;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,5(10)-estradiene-3,4,17-trione | | 17-oxo steroid;
3-oxo-Delta(1) steroid;
orthoquinones | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| s-sulphocysteine | | organic thiosulfate;
S-substituted L-cysteine | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| estrone-3-glucuronide | | 17-oxo steroid;
beta-D-glucosiduronic acid;
steroid glucosiduronic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,4-dihydroxyphenylacetaldehyde | | alpha-CH2-containing aldehyde;
catechols;
phenylacetaldehydes | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| caprylates | | fatty acid anion 8:0;
straight-chain saturated fatty acid anion | human metabolite;
Saccharomyces cerevisiae metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1-hydroxyethyl radical | | organic anion | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| (20s)-20-hydroxycholesterol | | 20-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxyhypusine | | L-lysine derivative;
non-proteinogenic L-alpha-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,7,12-trihydroxycoprostanic acid | | 12alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
cholestanoic acid;
hydroxy monocarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| triiodothyronine sulfate | | aryl sulfate;
O-sulfoamino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,7,12-trihydroxycholestan-26-oic acid | | 12alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
hydroxy monocarboxylic acid;
steroid acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| erythrose 4-phosphate | | erythrose phosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n(8)-acetylspermidine | | acetylspermidine | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 alpha-hydroxy-4-cholesten-3-one | | 3-oxo-Delta(4) steroid;
7alpha-hydroxy steroid;
cholestanoid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pristanic acid | | branched-chain saturated fatty acid;
long-chain fatty acid;
methyl-branched fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-glutamylcysteine | | gamma-glutamylcysteine | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 27-hydroxycholesterol | | 26-hydroxycholesterol | apoptosis inducer;
human metabolite;
mouse metabolite;
neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid | | dicarboxylic acid;
furoic acid | human metabolite;
uremic toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dehydroalanine | | 2,3-dehydroamino acid;
alpha,beta-unsaturated monocarboxylic acid;
amino acid zwitterion;
enamine;
non-proteinogenic alpha-amino acid | alkylating agent;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hypothiocyanite ion | | one-carbon compound;
sulfur oxoacid | antibacterial agent;
antifungal agent;
antiviral agent;
human metabolite;
oxidising agent;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-c-methylerythritol | | tetritol | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| succinylacetoacetate | | alpha,omega-dicarboxylic acid;
beta-diketone | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isoursodeoxycholic acid | | dihydroxy-5beta-cholanic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| mannitol-1-phosphate | | alditol 1-phosphate;
hexitol phosphate | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| triiodothyronine | | tetrahydrothiophenes;
thiolactone | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| kinetensin | | oligopeptide | histamine releasing agent;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| estra-1(10),4-diene-2,3,17-trione | | 17-oxo steroid;
3-oxo-Delta(4) steroid;
orthoquinones | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2'-deoxycytidine diphosphate | | 2'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-diphosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-methylserotonin | | phenols;
tryptamines | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-glutamylglutamine | | dipeptide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,4-dihydroxybutanoic acid | | 3-hydroxy fatty acid;
omega-hydroxy-short-chain fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-palmitoylglycine | | fatty amide;
N-acylglycine 16:0 | human metabolite;
marine metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-glutamyl-leucine | | glutamyl-L-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ribulose | | ribulose | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,4-dihydroxyphenylglycolaldehyde | | catechols;
hydroxyaldehyde | human metabolite;
mouse metabolite;
neurotoxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| androsterone sulfate | | 17-oxo steroid;
androstanoid;
steroid sulfate | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,7,12-trihydroxycoprostane | | 12alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| saccharopine | | amino acid opine;
L-lysine derivative | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| allysine | | allysine;
amino acid zwitterion;
aminoadipate semialdehyde;
non-proteinogenic L-alpha-amino acid | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| orotidylic acid | | pyrimidine ribonucleoside 5'-monophosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| allocholic acid | | 12alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
allo-bile acid;
C24-steroid | human metabolite;
marine metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta-ureidoisobutyric acid | | ureidocarboxylic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| kynurenine | | amino acid zwitterion;
kynurenine;
non-proteinogenic L-alpha-amino acid | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nicotinate ribonucleoside | | ammonium betaine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n(6)-(n-threonylcarbonyl)adenosine | | L-threonine derivative;
N-(adenosin-N(6)-ylcarbonyl)threonine | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sedoheptulose 7-phosphate | | ketoheptose phosphate;
sedoheptulose derivative | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| histidinol | | amino alcohol;
imidazoles | EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor;
Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thiocysteine | | amino acid zwitterion;
S-substituted L-cysteine | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nicotinic acid adenine dinucleotide | | nicotinic acid dinucleotide | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol | | 3beta-sterol | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| bradykinin, des-phe(8)-des-arg(9)- | | oligopeptide | human metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isobutyryl-1-carnitine | | methyl-branched fatty acyl-L-carnitine;
O-isobutyrylcarnitine;
saturated fatty acyl-L-carnitine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| threitol | | threitol | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| biotin | | biotins;
vitamin B7 | coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| angiotensin ii | | amino acid zwitterion;
angiotensin II | human metabolite | 1981 | 2017 | 31.7 | low | 4 | 49 | 47 | 11 | 6 | 0 |
| aceglutamide | | N-acetyl-L-amino acid;
N(2)-acetylglutamine;
N(2)-acyl-L-glutamine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aflatoxin b1 | | aflatoxin;
aromatic ether;
aromatic ketone | carcinogenic agent;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isospaglumic acid | | dipeptide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2'-deoxyadenosine triphosphate | | 2'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-diphosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-ethylhydracrylic acid | | branched-chain saturated fatty acid;
hydroxy fatty acid;
short-chain fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-methyl-3-oxovaleric acid | | 3-oxo monocarboxylic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| monoacetylcadaverine | | acetamides;
N-substituted cadaverine;
primary amino compound;
secondary carboxamide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta-citrylglutamic acid | | N-acyl-L-glutamic acid;
tetracarboxylic acid | human metabolite;
iron chelator | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| maltotriose | | maltotriose trisaccharide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholestane-3,7,12,26-tetrol | | 12alpha-hydroxy steroid;
26-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta-leucine | | beta-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-methylbutyrylglycine | | N-acylglycine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| neurotensin (1-8) | | peptide zwitterion;
peptide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholic acid | | 12alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
bile acid;
C24-steroid;
trihydroxy-5beta-cholanic acid | human metabolite;
mouse metabolite | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| erythritol | | butane-1,2,3,4-tetrol | antioxidant;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cortisone | | 11-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 5 alpha-androstane-3 beta,17 beta-diol | | 17beta-hydroxy steroid;
3beta-hydroxy steroid;
androstane-3,17-diol | Daphnia magna metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholesteryl palmitate | | cholesteryl ester | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lanosterol | | 14alpha-methyl steroid;
3beta-sterol;
tetracyclic triterpenoid | bacterial metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxyestradiol | | 17beta-hydroxy steroid;
2-hydroxy steroid | carcinogenic agent;
human metabolite;
metabolite;
mouse metabolite;
prodrug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxyisourate | | oxopurine | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-formyluracil | | aldehyde;
nucleobase analogue;
pyrimidone | human metabolite;
mutagen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| taurochenodeoxycholic acid | | bile acid taurine conjugate | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5'-methylthioadenosine | | thioadenosine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5'-deoxyadenosine | | 5'-deoxyribonucleoside;
adenosines | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isomaltose | | glycosylglucose | human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylneuraminic acid | | N-acetylneuraminic acids | antioxidant;
bacterial metabolite;
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glucosamine 6-phosphate | | 2-amino-2-deoxy-D-glucopyranose 6-phosphate | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| carnosine | | amino acid zwitterion;
dipeptide | anticonvulsant;
antineoplastic agent;
antioxidant;
Daphnia magna metabolite;
geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxytryptophan | | 5-hydroxytryptophan;
amino acid zwitterion;
hydroxy-L-tryptophan;
non-proteinogenic L-alpha-amino acid | human metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dopaquinone | | 1,2-benzoquinones;
amino acid zwitterion;
L-phenylalanine derivative | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pantetheine | | pantetheines;
thiol | human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tryptophanamide | | amino acid amide;
tryptophan derivative | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-diphosphomevalonic acid | | carboxyalkyl phosphate | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 7-dehydrocholesterol | | 3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid;
Delta(5),Delta(7)-sterol | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cysteinylglycine | | dipeptide zwitterion;
dipeptide | Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| desmosterol | | 3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
C27-steroid;
cholestanoid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| monoiodotyrosine | | amino acid zwitterion;
L-tyrosine derivative;
monoiodotyrosine;
non-proteinogenic L-alpha-amino acid | EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
human metabolite;
mouse metabolite | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| taurolithocholic acid | | bile acid taurine conjugate;
monocarboxylic acid amide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n'-formylkynurenine | | amino acid zwitterion;
N-formylkynurenine;
non-proteinogenic amino acid derivative;
non-proteinogenic L-alpha-amino acid | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| fuculose 1-phosphate | | deoxyaldohexose phosphate | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nicotinamide-beta-riboside | | N-glycosylnicotinamide;
pyridine nucleoside | geroprotector;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-hydroxyphenylacetaldehyde | | alpha-CH2-containing aldehyde;
phenylacetaldehydes | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trimethyllysine | | alpha-amino-acid cation | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| inositol 3,4-bisphosphate | | myo-inositol bisphosphate | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylglucosamine-1-phosphate | | N-acetyl-D-glucosamine 1-phosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 24,25-dihydrolanosterol | | 3beta-sterol;
tetracyclic triterpenoid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxyestrone | | 2-hydroxy steroid;
catechols | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-methoxyestrone | | 17-oxo steroid;
3-hydroxy steroid;
alicyclic ketone;
aromatic ether;
phenolic steroid;
phenols | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cortodoxone | | deoxycortisol;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| estradiol-3-glucuronide | | 17beta-hydroxy steroid;
beta-D-glucosiduronic acid;
steroid glucosiduronic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acetyl adenylate | | 5'-acylphosphoadenosin | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| epiandrosterone | | 17-oxo steroid;
3beta-hydroxy steroid;
androstanoid | androgen;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4,4-dimethylcholesta-8,14,24-trienol | | 3beta-sterol;
Delta(14) steroid | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| enkephalin, methionine | | pentapeptide;
peptide zwitterion | analgesic;
antineoplastic agent;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 7-ketolithocholic acid | | 3alpha-hydroxy steroid;
bile acid;
monohydroxy-5beta-cholanic acid;
oxo-5beta-cholanic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dephosphocoenzyme a | | adenosine 5'-phosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tretinoin | | retinoic acid;
vitamin A | anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| arachidonic acid | | icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid | Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite | 1981 | 2021 | 34.2 | low | 11 | 308 | 161 | 33 | 7 | 2 |
| 3-hydroxy-3-methylglutaryl-coenzyme a | | 3-hydroxy-3-methylglutaryl-CoA;
3-hydroxy fatty acyl-CoA | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| retinol | | retinol;
vitamin A | human metabolite;
mouse metabolite;
plant metabolite | 1992 | 1996 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| ribothymidine | | methyluridine | antigen;
Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| docosahexaenoate | | docosahexaenoic acid;
omega-3 fatty acid | algal metabolite;
antineoplastic agent;
Daphnia tenebrosa metabolite;
human metabolite;
mouse metabolite;
nutraceutical | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tetragastrin | | peptidyl amide;
tetrapeptide | anxiogenic;
human metabolite | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| prostaglandin d2 | | prostaglandins D | human metabolite;
mouse metabolite | 1982 | 2013 | 32.2 | low | 2 | 46 | 29 | 12 | 4 | 0 |
| hexanoyl-coenzyme a | | medium-chain fatty acyl-CoA | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| enkephalin, leucine | | pentapeptide;
peptide zwitterion | analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| tyrosine o-sulfate | | aryl sulfate;
L-tyrosine derivative;
O-sulfoamino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| retinaldehyde | | retinal;
vitamin A | gap junctional intercellular communication inhibitor;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| squalene | | triterpene | human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thyrotropin-releasing hormone | | peptide hormone;
tripeptide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-methylproline | | L-alpha-amino acid zwitterion;
L-proline derivative;
tertiary amino compound | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| citraconic acid | | dicarboxylic acid;
dicarboxylic fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| flavin-adenine dinucleotide | | flavin adenine dinucleotide;
vitamin B2 | cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
prosthetic group | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| flavin mononucleotide | | flavin mononucleotide;
vitamin B2 | bacterial metabolite;
coenzyme;
cofactor;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| mannose 1-phosphate | | mannose phosphate | fundamental metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycerylphosphorylcholine | | phosphocholines;
sn-glycerol 3-phosphates | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neuroprotective agent;
parasympatholytic;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| urocanic acid | | urocanic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cysteine sulfinic acid | | organosulfinic acid;
S-substituted L-cysteine | Escherichia coli metabolite;
human metabolite;
metabotropic glutamate receptor agonist;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholesterol acetate | | acetate ester;
cholesteryl ester | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,6-anhydro-beta-glucopyranose | | anhydrohexose | Arabidopsis thaliana metabolite;
biomarker;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycylvaline | | dipeptide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sodium taurodeoxycholate | | bile acid taurine conjugate | human metabolite | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| estrone sulfate | | 17-oxo steroid;
steroid sulfate | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydroxylysine | | 5-hydroxylysine;
hydroxy-L-lysine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycodeoxycholic acid | | bile acid glycine conjugate | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isobutyryl-coenzyme a | | methyl-branched fatty acyl-CoA;
short-chain fatty acyl-CoA | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| galactaric acid | | hexaric acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydroxycoprostane | | 3alpha-hydroxy steroid;
7alpha-hydroxy steroid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| angiotensin i, ile(5)- | | angiotensin;
peptide zwitterion | human metabolite;
neurotransmitter agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| fructosyl-glycine | | fructosamine;
glycine derivative;
glyco-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| arachidoyl-coenzyme a | | 11,12-saturated fatty acyl-CoA;
long-chain fatty acyl-CoA | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lignoceroyl-coenzyme a | | very long-chain fatty acyl-CoA | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxybenzimidazole | | benzimidazoles;
phenols | bacterial metabolite;
human metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-carbamylglutamate | | glutamic acid derivative;
ureas | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| citramalate | | dicarboxylic acid dianion | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-cresol sulfate | | aryl sulfate | gut flora metabolite;
human metabolite;
uremic toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sphingosine | | sphing-4-enine | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| bilirubin | | biladienes;
dicarboxylic acid | antioxidant;
human metabolite;
mouse metabolite | 1990 | 2005 | 26.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| dinoprostone | | prostaglandins E | human metabolite;
mouse metabolite;
oxytocic | 1979 | 2021 | 33.3 | low | 41 | 612 | 466 | 105 | 10 | 1 |
| dinoprost | | monocarboxylic acid;
prostaglandins Falpha | human metabolite;
mouse metabolite | 1979 | 2016 | 34.4 | low | 18 | 313 | 148 | 40 | 7 | 0 |
| leukotriene a4 | | epoxy fatty acid;
leukotriene;
long-chain fatty acid;
oxylipin;
polyunsaturated fatty acid | human metabolite;
mouse metabolite;
plant metabolite | 1990 | 2002 | 30.2 | low | 0 | 0 | 3 | 1 | 0 | 0 |
| prostaglandin b1 | | prostaglandins B | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| calcitriol | | D3 vitamins;
hydroxycalciol;
triol | antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical | 1985 | 1992 | 34.2 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| psychosine | | glycosylsphingoid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ubiquinone 9 | | ubiquinones | antioxidant;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta carotene | | carotenoid beta-end derivative;
cyclic carotene | antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A | 2007 | 2007 | 17.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| 11-cis-retinal | | retinal | chromophore;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| leukotriene b4 | | dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid | human metabolite;
mouse metabolite;
plant metabolite;
vasoconstrictor agent | 1981 | 2016 | 31.1 | low | 6 | 36 | 84 | 10 | 2 | 0 |
| leukotriene c4 | | leukotriene | bronchoconstrictor agent;
human metabolite;
mouse metabolite | 1994 | 2006 | 26.2 | low | 4 | 0 | 24 | 5 | 0 | 0 |
| prostaglandin f2beta | | prostaglandins Fbeta | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 8,11,14-eicosatrienoic acid | | fatty acid 20:3;
long-chain fatty acid | fungal metabolite;
human metabolite;
nutraceutical | 1985 | 2005 | 29.8 | low | 0 | 4 | 6 | 2 | 0 | 0 |
| 15-keto-5,8,11,13-eicosatetraenoic acid | | oxoicosatetraenoic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| alprostadil | | prostaglandins E | anticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent | 1979 | 2017 | 34.1 | low | 5 | 33 | 16 | 6 | 1 | 0 |
| 15-hydroxy-5,8,11,13-eicosatetraenoic acid | | (5Z,8Z,11Z,13E)-15-HETE | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxy-6,8,11,14-eicosatetraenoic acid | | HETE | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholecalciferol | | D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol;
steroid hormone | geroprotector;
human metabolite | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| leukotriene d4 | | dipeptide;
leukotriene;
organic sulfide | bronchoconstrictor agent;
human metabolite;
mouse metabolite | 1994 | 2009 | 22.6 | low | 0 | 0 | 5 | 3 | 0 | 0 |
| prostaglandin a2 | | prostaglandins A | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| prostaglandin b2 | | prostaglandins B | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| prostaglandin g2 | | prostaglandins G | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 9-deoxy-delta-9-prostaglandin d2 | | prostaglandins J | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 11-dehydro-thromboxane b2 | | thromboxane | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lipoxin a4 | | hydroxy polyunsaturated fatty acid;
lipoxin;
long-chain fatty acid | human metabolite;
metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-linolenic acid | | linolenic acid;
omega-6 fatty acid | human metabolite;
mouse metabolite;
plant metabolite | 1985 | 2000 | 32.9 | low | 3 | 5 | 4 | 0 | 0 | 0 |
| prostaglandin e3 | | prostaglandins E | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| leukotriene f-4 | | dipeptide;
leukotriene;
organic sulfide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| prostaglandin f1 | | prostaglandins Falpha | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| previtamin d(3) | | D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| brassicasterol | | 3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
ergostanoid;
phytosterols | algal metabolite;
animal metabolite;
biomarker;
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor;
human metabolite;
marine metabolite;
plant metabolite;
sterol biosynthesis inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| retinoyl beta-glucuronide | | glucuronic acids;
retinoid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| coenzyme q10 | | ubiquinones | antioxidant;
ferroptosis inhibitor;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| prostaglandin d3 | | prostaglandins D | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glyceryl 2-arachidonate | | 2-acylglycerol 20:4;
endocannabinoid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tocotrienol, alpha | | tocotrienol;
vitamin E | ferroptosis inhibitor;
human metabolite;
neuroprotective agent;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 11-ketotestosterone | | 11-oxo steroid;
17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid | androgen;
human metabolite;
marine xenobiotic metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| menatetrenone | | menaquinone | anti-inflammatory agent;
antioxidant;
bone density conservation agent;
human metabolite;
neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phthioic acid | | branched-chain saturated fatty acid;
fatty acid 26:0;
methyl-branched fatty acid;
very long-chain fatty acid | Aspergillus metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-decenoic acid | | 2-decenoic acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 9,11-linoleic acid | | octadeca-9,11-dienoic acid | anti-inflammatory agent;
antiatherogenic agent;
antineoplastic agent;
apoptosis inducer;
bacterial xenobiotic metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 9-hydroxy-10,12-octadecadienoic acid | | HODE;
octadecadienoic acid | human metabolite;
metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 17-phenyltrinorprostaglandin e2 | | alicyclic ketone;
beta-hydroxy ketone;
hydroxy monocarboxylic acid;
olefinic compound;
oxo monocarboxylic acid;
prostanoid;
secondary alcohol | human metabolite;
prostaglandin receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thromboxane b2 | | thromboxanes B | human metabolite;
mouse metabolite | 1979 | 2021 | 32.8 | high | 177 | 1,103 | 953 | 167 | 62 | 1 |
| thromboxane b3 | | thromboxanes B | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 12-hydroxy-5,8,10,14-eicosatetraenoic acid | | (5Z,8Z,10E,14Z)-12-hydroxyicosatetraenoic acid;
HETE | human metabolite;
pro-angiogenic agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 20-hydroxy-5,8,11,14-eicosatetraenoic acid | | HETE;
hydroxy monocarboxylic acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-oxo-6,8,11,14-eicosatetraenoic acid | | oxoicosatetraenoic acid | human metabolite;
immunomodulator;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 8-isoprostaglandin e2 | | cyclic ketone;
diol;
prostanoid;
secondary alcohol | bronchoconstrictor agent;
human metabolite;
rat metabolite;
vasoconstrictor agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| oleylamide | | primary fatty amide | human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| monolinolein | | 1-acylglycerol 18:2;
rac-1-monoacylglycerol | antiviral agent;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,25-dihydroxy-24-oxo-vitamin d3 | | hydroxycalciol;
oxocalciol;
tertiary alpha-hydroxy ketone | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| calcifediol | | D3 vitamins;
diol;
hydroxycalciol | bone density conservation agent;
human metabolite;
metabolite;
mouse metabolite;
nutraceutical | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hyodeoxycholic acid | | 5beta-cholanic acids;
6alpha,20xi-murideoxycholic acid;
bile acid;
C24-steroid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| vitamin k 1 | | phylloquinones;
vitamin K | cofactor;
human metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cerium | | CE(18:2);
cholesteryl octadeca-9,12-dienoate | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| xylulose | | xylulose | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 11-dehydrocorticosterone | | 11-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
corticosteroid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-butyl oleate | | fatty acid ester | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 8-hydroxyadenine | | 6-aminopurines;
heteroaryl hydroxy compound;
nucleobase analogue;
oxopurine | bacterial metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| erucyl amide | | 13-docosenamide | EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite;
mammalian metabolite;
plant metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| vitamin mk 8 | | menaquinone | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2,3-oxidosqualene | | 2,3-epoxysqualene | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-keto-4-hydroxyglutarate | | oxo dicarboxylate | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxyribose | | deoxypentose | human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| iditol | | iditol | fungal metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glutamate | | glutamate(1-);
polar amino acid zwitterion | EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor;
human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| fumarates | | butenedioate;
C4-dicarboxylate | human metabolite;
metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cerotate | | fatty acid anion 26:0;
omega-methyl fatty acid anion;
very long-chain fatty acid anion | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adenosine triphosphate | | nucleoside 5'-triphoshate(4-) | cofactor;
fundamental metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| docosapentaenoic acid | | docosapentaenoic acid;
omega-3 fatty acid | algal metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-methylbutyrylcarnitine | | C5-acylcarnitine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hexanoylcarnitine | | hexanoate ester;
O-acylcarnitine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| linoleamide | | primary fatty amide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 13-cis-retinal | | retinal | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-hydroxyretinoic acid | | retinoid;
secondary allylic alcohol | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-oxo-2-nonenal | | enal;
enone | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 20,22-dihydroxycholesterol | | 20-hydroxy steroid;
22-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
cholestanoid;
oxysterol | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| biotinate | | monocarboxylic acid anion;
vitamin B7 | cofactor;
human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 beta-hydroxycortisol | | 11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
6beta-hydroxy steroid;
C21-steroid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | human metabolite;
mammalian metabolite;
probe | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| fuculose | | deoxyketohexose | Escherichia coli metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-glutamylvaline | | glutamyl-L-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ophthalmic acid | | L-glutamine derivative | biomarker;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acetylcarnitine | | O-acetylcarnitine;
saturated fatty acyl-L-carnitine | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adenosine diphosphate | | nucleoside 5'-diphosphate(3-) | fundamental metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cyclic amp | | organophosphate oxoanion | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,23,25-trihydroxyvitamin d3 | | D3 vitamins;
hydroxy seco-steroid;
hydroxycalciol;
tetrol | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphocreatine | | phosphagen;
phosphoamino acid | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ursodoxicoltaurine | | bile acid taurine conjugate | anti-inflammatory agent;
apoptosis inhibitor;
bone density conservation agent;
cardioprotective agent;
human metabolite;
neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| arachidonoylserotonin | | N-acylserotonin;
phenols | anti-inflammatory agent;
anticonvulsant;
antioxidant;
capsaicin receptor antagonist;
EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor;
human metabolite;
signalling molecule | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| homocarnosine | | dipeptide zwitterion;
dipeptide;
homocarnosine;
L-histidine derivative;
N-acyl-L-alpha-amino acid anion;
N-acyl-L-alpha-amino acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxyproline | | 3-hydroxyproline;
amino acid zwitterion;
D-proline derivative | bacterial metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cytidine diphosphate choline | | nucleotide-(amino alcohol)s;
phosphocholines | human metabolite;
mouse metabolite;
neuroprotective agent;
psychotropic drug;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| octanoylcarnitine | | O-octanoylcarnitine;
saturated fatty acyl-L-carnitine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| palmitoylcarnitine | | O-palmitoylcarnitine;
saturated fatty acyl-L-carnitine | EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cyclic 3',5'-thymidine monophosphate | | 3',5'-cyclic pyrimidine nucleotide | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pristanal | | 2-methyl-branched fatty aldehyde;
saturated fatty aldehyde | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lanosten-3-ol-32-al | | 14alpha-formyl steroid;
3beta-sterol;
tetracyclic triterpenoid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thiamine pyrophosphate | | organophosphate oxoanion;
vitamin B1 | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adenosine monophosphate | | nucleoside 5'-monophosphate(2-) | cofactor;
fundamental metabolite;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nad | | organophosphate oxoanion | cofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite | 1978 | 1989 | 41.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| cob(ii)alamin | | cobalamin | cofactor;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nociceptin | | organic molecular entity;
polypeptide | human metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxy-3-methyl-hexanoic acid | | 3-hydroxy monocarboxylic acid;
volatile organic compound | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uridine diphosphate | | nucleoside 5'-diphosphate(3-) | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylgalactosamine-1-phosphate | | D-galactosamine 1-phosphate | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-phospho-5-s-methylthioribulose | | organophosphate oxoanion | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| s-adenosylmethionine | | organic cation;
sulfonium compound | coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 10-nitro-oleic acid | | long-chain fatty acid;
monounsaturated fatty acid;
nitro fatty acid | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ticrynafen | | monocarboxylic acid anion;
organophosphate oxoanion | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| s-(1,2-dicarboxyethyl)cysteine | | L-cysteine thioether;
tricarboxylic acid | human metabolite;
Maillard reaction product | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| neurotensin | | peptide hormone | human metabolite;
mitogen;
neurotransmitter;
vulnerary | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| apelin-13 peptide | | oligopeptide | antihypertensive agent;
autophagy inhibitor;
biomarker;
human metabolite;
neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe | | polypeptide | apoptosis inhibitor;
human metabolite;
neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| taurolithocholic acid 3-sulfate | | steroid sulfate oxoanion | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| inositol 1,3,4-trisphosphate | | inositol phosphate oxoanion | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| diadenosine tetraphosphate | | organophosphate oxoanion | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-ketoarginine | | 2-oxo monocarboxylic acid;
zwitterion | human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adenosine diphosphate glucose | | NDP-alpha-D-glucose(2-);
ribonucleoside 5'-diphosphate-alpha-D-glucose(2-) | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nicotinate mononucleotide | | organophosphate oxoanion | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| oleoylcarnitine | | monounsaturated fatty acyl-L-carnitine | glycine transporter 2 inhibitor;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uridine diphosphate n-acetylgalactosamine | | nucleotide-sugar oxoanion | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 6-phosphogluconolactone | | organophosphate oxoanion | human metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxyisovalerylcarnitine | | O-acylcarnitine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| angiotensin i | | angiotensin;
peptide zwitterion | antihypertensive agent;
cardioprotective agent;
human metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 9-PAHSA | | FAHFA;
long-chain fatty acid | anti-inflammatory agent;
human metabolite;
hypoglycemic agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| angiotensin i | | angiotensin;
peptide zwitterion | human metabolite;
neurotransmitter agent | 1986 | 2015 | 27.5 | low | 0 | 1 | 6 | 2 | 1 | 0 |
| lugdunin | | homodetic cyclic peptide;
indoles;
macrocycle;
peptide antibiotic;
thiazolidines | human metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cyclic gmp | | 3',5'-cyclic purine nucleotide;
guanyl ribonucleotide | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1982 | 2013 | 28.5 | low | 4 | 9 | 43 | 11 | 1 | 0 |
| deoxyguanosine | | purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxyinosine | | purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxyguanosine triphosphate | | deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-triphosphate | Arabidopsis thaliana metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 7,8-dihydroneopterin | | dihydropterin;
neopterins | Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxyinosine monophosphate | | deoxyinosine phosphate;
purine 2'-deoxyribonucleoside 5'-monophosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| guanosine diphosphate mannose | | GDP-D-mannose | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| guanine | | 2-aminopurines;
oxopurine;
purine nucleobase | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| inosinic acid | | inosine phosphate;
purine ribonucleoside 5'-monophosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| inosine | | inosines;
purines D-ribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1987 | 1987 | 37.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| inosine triphosphate | | inosine phosphate;
purine ribonucleoside 5'-triphosphate | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sapropterin | | 5,6,7,8-tetrahydrobiopterin | coenzyme;
cofactor;
diagnostic agent;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| folic acid | | folic acids;
N-acyl-amino acid | human metabolite;
mouse metabolite;
nutrient | 2019 | 2019 | 5.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| dyspropterin | | biopterins;
tetrahydropterin | human metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 8-nitroguanosine 3',5'-cyclic monophosphate | | 3',5'-cyclic purine nucleotide;
C-nitro compound | biomarker;
Brassica napus metabolite;
human metabolite;
signalling molecule | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n(2),n(2)-dimethylguanosine | | methylguanosine | human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| creatinine | | imidazolidinone;
lactam | diagnostic agent;
human metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| apelin-12 peptide | | oligopeptide | biomarker;
human blood serum metabolite;
human metabolite;
neuroprotective agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| alpha-hydroxyglutarate | | 2-hydroxydicarboxylic acid;
dicarboxylic fatty acid | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| alpha-ketoadipic acid | | oxo dicarboxylic acid | human urinary metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-carbamoyl-beta-alanine | | beta-alanine derivative | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-aminobutyraldehyde | | aminobutanal;
omega-aminoaldehyde | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-hydroxybenzaldehyde | | hydroxybenzaldehyde | EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ethylene glycol | | ethanediol;
glycol | metabolite;
mouse metabolite;
solvent;
toxin | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| agmatine | | guanidines;
primary amino compound | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| allantoic acid | | ureas | mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aminoacetone | | methyl ketone;
propanones | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ammonium hydroxide | | azane;
gas molecular entity;
mononuclear parent hydride | EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant | 1988 | 2001 | 29.0 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| hydrobromic acid | | gas molecular entity;
hydrogen halide;
mononuclear parent hydride | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| butyraldehyde | | butanals | biomarker;
Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cadaverine | | alkane-alpha,omega-diamine | Daphnia magna metabolite;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| carbamyl phosphate | | acyl monophosphate;
one-carbon compound | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydrochloric acid | | chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride | mouse metabolite | 1984 | 2004 | 31.8 | low | 0 | 4 | 0 | 2 | 0 | 0 |
| coproporphyrinogen iii | | coproporphyrinogen | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,2-dihydroxy-1,2-dihydronaphthalene | | dihydronaphthalenes;
naphthalenediols | bacterial xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-nitrophenylphosphate | | aryl phosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n(1)-methylnicotinamide | | pyridinium ion | algal metabolite;
anti-inflammatory agent;
human urinary metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphonoacetaldehyde | | phosphonic acids | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-guanidinobutyric acid | | guanidines;
monocarboxylic acid;
zwitterion | fungal metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphoglycolate | | carboxyalkyl phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydrogen selenide | | mononuclear parent hydride;
selenium hydride | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,3-dimethylallyl pyrophosphate | | prenol phosphate | epitope;
Escherichia coli metabolite;
mouse metabolite;
phosphoantigen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| diethyl phosphate | | dialkyl phosphate | human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| o,o-diethyl phosphorothionate | | organic thiophosphate | human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| formaldehyde | | aldehyde;
one-carbon compound | allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| carbonic acid | | carbon oxoacid;
chalcocarbonic acid | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydantoin-5-propionic acid | | imidazolidine-2,4-dione;
monocarboxylic acid | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydroquinone | | benzenediol;
hydroquinones | antioxidant;
carcinogenic agent;
cofactor;
Escherichia coli metabolite;
human xenobiotic metabolite;
mouse metabolite;
skin lightening agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydroxymethylbilane | | bilanes | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lactaldehyde | | hydroxyaldehyde;
propanals | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| naphthalene | | naphthalenes;
ortho-fused bicyclic arene | apoptosis inhibitor;
carcinogenic agent;
environmental contaminant;
mouse metabolite;
plant metabolite;
volatile oil component | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| niacinamide | | pyridine alkaloid;
pyridinecarboxamide;
vitamin B3 | anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor | 2007 | 2016 | 11.3 | low | 0 | 0 | 0 | 1 | 2 | 0 |
| niacin | | pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3 | antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent | 1987 | 2002 | 29.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| hydroxide ion | | oxygen hydride | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| orotic acid | | pyrimidinemonocarboxylic acid | Escherichia coli metabolite;
metabolite;
mouse metabolite | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 4-nitrophenol | | 4-nitrophenols | human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| parathion | | C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenanthrene | | ortho-fused polycyclic arene;
ortho-fused tricyclic hydrocarbon;
phenanthrenes | environmental contaminant;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenol | | phenols | antiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| porphobilinogen | | aralkylamino compound;
dicarboxylic acid;
pyrroles | Escherichia coli metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| propylene glycol | | glycol;
propane-1,2-diols | allergen;
human xenobiotic metabolite;
mouse metabolite;
protic solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyridoxine 5-phosphate | | vitamin B6 phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| succinic semialdehyde | | aldehydic acid | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| tartronate semialdehyde | | 2-hydroxy monocarboxylic acid;
3-oxo monocarboxylic acid;
aldehyde | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uroporphyrinogen iii | | uroporphyrinogen | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isopentenyl pyrophosphate | | prenol phosphate | antigen;
antioxidant;
epitope;
Escherichia coli metabolite;
mouse metabolite;
phosphoantigen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 6-hydroxymelatonin | | acetamides;
tryptamines | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adrenic acid | | docosatetraenoic acid | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| benzo(a)pyrene | | ortho- and peri-fused polycyclic arene | carcinogenic agent;
mouse metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| caffeine | | purine alkaloid;
trimethylxanthine | adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic | 1988 | 2004 | 28.3 | low | 0 | 1 | 4 | 1 | 0 | 0 |
| chloral hydrate | | aldehyde hydrate;
ethanediol;
organochlorine compound | general anaesthetic;
mouse metabolite;
sedative;
xenobiotic | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| quinone | | 1,4-benzoquinones | cofactor;
human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,7-dimethylxanthine | | dimethylxanthine | central nervous system stimulant;
human blood serum metabolite;
human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| theobromine | | dimethylxanthine | adenosine receptor antagonist;
bronchodilator agent;
food component;
human blood serum metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent | 1984 | 2001 | 35.0 | low | 2 | 5 | 1 | 1 | 0 | 0 |
| aspartic acid | | aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
mouse metabolite;
neurotransmitter | 1989 | 2012 | 25.0 | low | 0 | 1 | 1 | 0 | 1 | 0 |
| uridine diphosphate | | pyrimidine ribonucleoside 5'-diphosphate;
uridine 5'-phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| galactose | | D-galactose;
galactopyranose | Escherichia coli metabolite;
mouse metabolite | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cytidine diphosphate | | cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-diphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uridine triphosphate | | pyrimidine ribonucleoside 5'-triphosphate;
uridine 5'-phosphate | Escherichia coli metabolite;
mouse metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| phenylalanine | | amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
phenylalanine;
proteinogenic amino acid | algal metabolite;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
Escherichia coli metabolite;
human xenobiotic metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cytidine triphosphate | | cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-triphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-naphthaldehyde | | naphthaldehyde | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-naphthaldehyde | | naphthaldehyde | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ornithine | | non-proteinogenic L-alpha-amino acid;
ornithine | algal metabolite;
hepatoprotective agent;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| arginine | | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical | 1988 | 2006 | 29.6 | low | 2 | 1 | 32 | 3 | 0 | 0 |
| methylamine | | methylamines;
one-carbon compound;
primary aliphatic amine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ethylene oxide | | gas molecular entity;
oxacycle;
saturated organic heteromonocyclic parent | allergen;
mouse metabolite;
mutagen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| vinylidene chloride | | chloroethenes | carcinogenic agent;
mouse metabolite;
mutagen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trichloroacetaldehyde | | aldehyde;
organochlorine compound | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trichloroacetic acid | | monocarboxylic acid;
organochlorine compound | carcinogenic agent;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gibberellic acid | | C19-gibberellin;
gibberellin monocarboxylic acid;
lactone;
organic heteropentacyclic compound | mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trichloroethylene | | chloroethenes | inhalation anaesthetic;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pyridoxic acid | | hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6 | human urinary metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-nitronaphthalene | | mononitronaphthalene | environmental contaminant;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta-glucono-1,5-lactone | | aldono-1,5-lactone;
gluconolactone | animal metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-naphthoic acid | | naphthoic acid | mouse metabolite;
xenobiotic metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| methylphenyl carbinol | | aromatic alcohol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-hydroxyacetophenone | | monohydroxyacetophenone | fungal metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| styrene | | styrenes;
vinylarene;
volatile organic compound | mouse metabolite;
mutagen;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-phenylacetamide | | monocarboxylic acid amide | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-bromophenol | | bromophenol | human urinary metabolite;
human xenobiotic metabolite;
marine metabolite;
mouse metabolite;
persistent organic pollutant;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ethylene dibromide | | bromoalkane;
bromohydrocarbon | algal metabolite;
carcinogenic agent;
fumigant;
marine metabolite;
mouse metabolite;
mutagen | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| bromobenzene | | bromoarene;
bromobenzenes;
volatile organic compound | hepatotoxic agent;
mouse metabolite;
non-polar solvent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-heptanone | | dialkyl ketone;
methyl ketone | mouse metabolite;
pheromone | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2,2,2-trichloroethanol | | chloroethanol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-naphthol | | naphthol | antinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| D-proline | | D-alpha-amino acid zwitterion;
D-alpha-amino acid;
proline | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| paraoxon | | aryl dialkyl phosphate;
organophosphate insecticide | EC 3.1.1.7 (acetylcholinesterase) inhibitor;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| aminoimidazole carboxamide | | aminoimidazole;
monocarboxylic acid amide | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| methyl-4-tyramine | | tyramines | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphoadenosine phosphosulfate | | acyl sulfate;
adenosine bisphosphate;
purine ribonucleoside bisphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adenosine phosphosulfate | | acyl monophosphate;
acyl sulfate;
adenosine 5'-phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| fructose-1,6-diphosphate | | D-fructofuranose 1,6-bisphosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydroxyhydroquinone | | benzenetriol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,2-dihydroxynaphthalene | | naphthalenediol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| propiolaldehyde | | terminal acetylenic compound;
ynal | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenylphosphate | | aryl phosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-cyclohexylformamide | | alicyclic compound;
formamides | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| deoxycytidine monophosphate | | 2'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-monophosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| nicotinamide mononucleotide | | nicotinamide mononucleotide | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydroferulic acid | | guaiacols;
monocarboxylic acid;
phenylpropanoid | antioxidant;
human xenobiotic metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2'-deoxyadenosine triphosphate | | 2'-deoxyadenosine 5'-phosphate;
purine 2'-deoxyribonucleoside 5'-triphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| fucose | | fucopyranose;
L-fucose | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| uridine diphosphate galactose | | UDP-D-galactose | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-naphthalenemethanol | | naphthylmethanol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| diadenosine tetraphosphate | | diadenosyl tetraphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| d-glutamate | | D-alpha-amino acid;
glutamic acid | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydroiodic acid | | gas molecular entity;
hydrogen halide;
mononuclear parent hydride | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trichloroepoxyethane | | epoxide | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glutamic acid | | glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical | 1989 | 1994 | 32.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| adenosine diphosphate ribose | | ADP-sugar | Escherichia coli metabolite;
mouse metabolite | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| phosphopantothenic acid | | amidoalkyl phosphate | Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cyromazine | | triamino-1,3,5-triazine | mouse metabolite;
triazine insecticide | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glucose, (beta-d)-isomer | | D-glucopyranose | epitope;
mouse metabolite | 1980 | 2017 | 31.9 | low | 0 | 10 | 11 | 1 | 2 | 0 |
| thymidine 5'-triphosphate | | pyrimidine 2'-deoxyribonucleoside 5'-triphosphate;
thymidine phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2'-deoxyuridylic acid | | deoxyuridine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-monophosphate | Escherichia coli metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| obtusifoliol | | 14alpha-methyl steroid;
3beta-sterol | mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glutathione disulfide | | glutathione derivative;
organic disulfide | Escherichia coli metabolite;
mouse metabolite | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| 3'-cmp | | cytidine 3'-phosphate;
pyrimidine ribonucleoside 3'-monophosphate | Escherichia coli metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 7-methylxanthine | | oxopurine;
purine alkaloid | human xenobiotic metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cifostodine | | 2',3'-cyclic pyrimidine nucleotide | Escherichia coli metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n'-methyl-2-pyridone-5-carboxamide | | methylpyridines;
pyridinecarboxamide;
pyridone | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-methyluric acid | | oxopurine | human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cyclopropylamine | | primary aliphatic amine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 6-hydroxynicotinic acid | | monohydroxypyridine | Arabidopsis thaliana metabolite;
human urinary metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| xanthosine 5'-triphosphate | | purine ribonucleoside 5'-monophosphate;
xanthosine 5'-phosphate | Escherichia coli metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-naphthalenemethanol | | naphthylmethanol | mouse metabolite;
xenobiotic metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| xanthurenic acid 8-methyl ether | | aromatic ether;
monohydroxyquinoline;
quinolinemonocarboxylic acid | carcinogenic agent;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glucose | | D-glucopyranose | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,3,7-trimethylurate | | oxopurine | human blood serum metabolite;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-methylxanthine | | 1-methylxanthine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3,7-dimethyluric acid | | oxopurine | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| biocytin | | azabicycloalkane;
L-alpha-amino acid zwitterion;
L-lysine derivative;
monocarboxylic acid amide;
non-proteinogenic L-alpha-amino acid;
thiabicycloalkane;
ureas | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| d-aspartic acid | | aspartic acid;
D-alpha-amino acid | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| coenzyme a | | adenosine 3',5'-bisphosphate | coenzyme;
Escherichia coli metabolite;
mouse metabolite | 1988 | 1993 | 33.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| 3,4-dihydroxyphenylglycol | | catechols;
tetrol | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| homocysteine | | amino acid zwitterion;
homocysteine;
serine family amino acid | fundamental metabolite;
mouse metabolite | 1986 | 2019 | 22.8 | low | 0 | 1 | 2 | 2 | 1 | 0 |
| 1,7-dimethyluric acid | | oxopurine | human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 24-methylenecholesterol | | 3beta-hydroxy-Delta(5)-steroid;
3beta-sterol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| succinyl-coenzyme a | | omega-carboxyacyl-CoA | Escherichia coli metabolite;
inhibitor;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acetoacetyl coa | | 3-oxo-fatty acyl-CoA | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2,8-dihydroxyadenine | | 6-aminopurines;
diol;
heteroaryl hydroxy compound;
oxopurine | human urinary metabolite;
mammalian metabolite;
mouse metabolite;
nephrotoxic agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| propionyl-coenzyme a | | acyl-CoA | Escherichia coli metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 21-deoxycortisol | | 11beta-hydroxy steroid;
17alpha-hydroxy-C21-steroid;
deoxycortisol;
tertiary alpha-hydroxy ketone | human blood serum metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| stearoyl-coenzyme a | | 11,12-saturated fatty acyl-CoA;
long-chain fatty acyl-CoA | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| imidazoleacetic acid | | imidazoles;
monocarboxylic acid | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-hydroxyphenanthrene | | phenanthrol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2,5-dihydroxypyridine | | dihydroxypyridine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cerium | | cholesteryl ester | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 6,6-dimethyl-2-methylenebicyclo(3.1.1)heptan-3-ol | | carbobicyclic compound;
pinane monoterpenoid;
secondary alcohol | GABA modulator;
mouse metabolite;
plant metabolite;
volatile oil component | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ecgonine methyl ester | | methyl ester;
tertiary amino compound;
tropane alkaloid | analgesic;
central nervous system depressant;
metabolite;
mouse metabolite;
opioid analgesic;
peripheral nervous system drug | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine | | hydroxylamine;
imidazopyridine | carcinogenic agent;
genotoxin;
human xenobiotic metabolite;
mouse metabolite;
mutagen;
neurotoxin;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholest-5-en-3 beta,7 alpha-diol | | 3beta-hydroxy-Delta(5)-steroid;
7alpha-hydroxy steroid;
oxysterol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| s-chloromethylglutathione | | organochlorine compound;
S-substituted glutathione | alkylating agent;
bacterial xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-acetylamino-6-formylamino-3-methyluracil | | formamidopyrimidine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| anserine | | beta-alanine derivative;
dipeptide;
zwitterion | animal metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5,6-dihydroxyindole | | dihydroxyindole | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5,6-dihydroxy-2-indolylcarboxylic acid | | dihydroxyindole | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| protoporphyrinogen | | porphyrinogens | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| inositol-3,4,5,6-tetrakisphosphate | | myo-inositol tetrakisphosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 24-hydroxycholesterol | | 24-hydroxycholesterol | biomarker;
human blood serum metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phytosphingosine | | amino alcohol;
sphingoid;
triol | mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| butyryl-coenzyme a | | butanoyl-CoAs | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-acetylputrescine | | N-monoacetylalkane-alpha,omega-diamine;
N-substituted putrescine | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cdp ethanolamine | | nucleotide-(amino alcohol)s;
phosphoethanolamine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| galactose-1-phosphate | | alpha-D-hexose 1-phosphate;
D-galactopyranose 1-phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine | | 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 30:0;
tetradecanoate ester | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| proline | | amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid | algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 1981 | 1997 | 36.6 | low | 0 | 4 | 3 | 0 | 0 | 0 |
| d-glutamine | | amino acid zwitterion;
D-alpha-amino acid;
glutamine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| diquafosol | | pyrimidine ribonucleoside 5'-tetraphosphate;
uridine 5'-phosphate | mouse metabolite;
P2Y2 receptor agonist | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 19-hydroxytestosterone | | 17beta-hydroxy steroid;
19-hydroxy steroid;
3-oxo-Delta(4) steroid | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxy-1,4-benzoquinone | | monohydroxy-1,4-benzoquinones | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sorbitol 6-phosphate | | alditol 6-phosphate;
glucitol phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| adenosine 3'-phosphate-5'-phosphate | | adenosine bisphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| alpha-ribazole | | 1-ribosylbenzimidazole;
dimethylbenzimidazole | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| saicar | | 1-(phosphoribosyl)imidazolecarboxamide | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thymidine 5'-diphosphate | | pyrimidine 2'-deoxyribonucleoside 5'-diphosphate;
thymidine phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| hydromethylthionine | | aromatic amine;
phenothiazines;
tertiary amino compound | bacterial xenobiotic metabolite;
fluorochrome;
mouse metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxykynuramine | | hydroxykynurenamine;
primary amino compound | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sedoheptulose 1,7-bisphosphate | | ketoheptose phosphate;
sedoheptulose derivative | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| diadenosine triphosphate | | diadenosyl triphosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| carboxyaminoimidazole ribotide | | 1-(phosphoribosyl)imidazole;
aminoimidazole;
imidazole-4-carboxylic acid | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| isovaleryl-coenzyme a | | methylbutanoyl-CoA;
short-chain fatty acyl-CoA | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lauroyl-coenzyme a | | medium-chain fatty acyl-CoA | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phenylacetyl-coenzyme a | | acyl-CoA | Escherichia coli metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-formamidoimidazole-4-carboxamide ribotide | | 1-(phosphoribosyl)imidazolecarboxamide | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| campesterol | | 3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
C28-steroid;
phytosterols | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gamma-glutamyl phosphate | | gamma-glutamyl phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-amino-6-ribitylamino-2,4-(1h,3h)pyrimidinedione | | aminouracil;
hydroxypyrimidine | Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sitosterol, (3beta)-isomer | | 3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
C29-steroid;
phytosterols;
stigmastane sterol | anticholesteremic drug;
antioxidant;
mouse metabolite;
plant metabolite;
sterol methyltransferase inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| androstane-3,17-dione, (5alpha)-isomer | | 3-oxo-5alpha-steroid;
androstane-3,17-dione | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 21-hydroxypregnenolone | | 21-hydroxy steroid;
hydroxypregnenolone;
primary alpha-hydroxy ketone | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| epietiocholanolone | | 17-oxo steroid;
3beta-hydroxy steroid;
androstanoid | androgen;
animal metabolite;
human blood serum metabolite;
mouse metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 19-hydroxy-4-androstene-3,17-dione | | 17-oxo steroid;
19-hydroxy steroid;
3-oxo steroid;
androstanoid | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glyceraldehyde 3-phosphate | | glyceraldehyde 3-phosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ribulose 5-phosphate | | ribulose 5-phosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| xylulose-5-phosphate, (d)-isomer | | xylulose 5-phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glycerate 1,3-biphosphate | | 2,3-bisphosphoglyceric acid;
acyl monophosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| arabinose | | L-arabinose | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glucosamine | | D-glucosamine | Escherichia coli metabolite;
geroprotector;
mouse metabolite | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| raffinose | | raffinose family oligosaccharide;
trisaccharide | mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| xanthosine 5'-triphosphate | | purine ribonucleoside 5'-triphosphate;
xanthosine 5'-phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| galactose | | D-galactopyranose | epitope;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| galactose | | D-galactopyranose | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| s-adenosyl-3-methylthiopropylamine | | adenosines;
sulfonium compound | Escherichia coli metabolite;
human urinary metabolite;
mouse metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 6-phosphonoglucono-delta-lactone | | aldonolactone phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| inositol 1,4,5-trisphosphate | | myo-inositol trisphosphate | mouse metabolite | 1987 | 1996 | 33.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| stachyose | | raffinose family oligosaccharide;
tetrasaccharide | mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| ketodihydrosphingosine | | 2-amino-1-hydroxyoctadecan-3-one | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| androstane-3,17-dione, (5beta)-isomer | | 3-oxo-5beta-steroid;
androstane-3,17-dione | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| pantothenylcysteine 4'-phosphate | | L-cysteine derivative | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dehydroascorbic acid | | dehydroascorbic acid;
vitamin C | coenzyme;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| beta-sulfopyruvic acid | | carboxyalkanesulfonic acid | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2-hydroxypropylphosphonic acid | | phosphonic acids;
secondary alcohol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| inositol-1,4,5,6-tetrakisphosphate | | myo-inositol tetrakisphosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| maleic acid | | butenedioic acid | algal metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n(1)-(5-phosphoribosyl)-5,6-dimethylbenzimidazole | | 1-ribosylbenzimidazole;
dimethylbenzimidazole;
ribose monophosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| prostaglandin h2 | | olefinic compound;
oxylipin;
prostaglandins H;
secondary alcohol | mouse metabolite | 1982 | 2004 | 34.0 | low | 0 | 15 | 11 | 2 | 0 | 0 |
| oleic acid | | octadec-9-enoic acid | antioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent | 1982 | 2004 | 30.0 | low | 1 | 2 | 7 | 2 | 0 | 0 |
| farnesyl pyrophosphate | | farnesyl diphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| geranyl pyrophosphate | | polyprenyl diphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,5-dihydro-fad | | flavin adenine dinucleotide | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cocaine | | benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid | adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic | 1994 | 2001 | 27.8 | low | 1 | 0 | 3 | 1 | 0 | 0 |
| eicosapentaenoic acid | | icosapentaenoic acid;
omega-3 fatty acid | anticholesteremic drug;
antidepressant;
antineoplastic agent;
Daphnia galeata metabolite;
fungal metabolite;
micronutrient;
mouse metabolite;
nutraceutical | 1981 | 2007 | 33.5 | low | 2 | 13 | 11 | 4 | 0 | 0 |
| s-hydroxymethylglutathione | | S-substituted glutathione | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| geranylgeranyl pyrophosphate | | geranylgeranyl diphosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cytidine monophosphate n-acetylneuraminic acid | | CMP-N-acyl-beta-neuraminic acid | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 4-phosphoerythronate | | 4-phosphoerythronic acid | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| colfosceril palmitate | | 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 32:0 | mouse metabolite;
surfactant | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| lyso-pc | | 1-O-acyl-sn-glycero-3-phosphocholine;
lysophosphatidylcholine 16:0 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| riboflavin | | flavin;
vitamin B2 | anti-inflammatory agent;
antioxidant;
cofactor;
Escherichia coli metabolite;
food colouring;
fundamental metabolite;
human urinary metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trans-4-coumaric acid | | 4-coumaric acid | food component;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 3-hydroxybutyryl-coenzyme a | | 3-hydroxyacyl-CoA;
hydroxybutanoyl-CoA | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| malonyl coenzyme a | | malonyl-CoAs | EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor;
Escherichia coli metabolite;
metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| palmitoyl coenzyme a | | 11,12-saturated fatty acyl-CoA;
3-substituted propionyl-CoA;
long-chain fatty acyl-CoA;
palmitoyl bioconjugate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydrosphingosine 1-phosphate | | sphingoid 1-phosphate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| caffeic acid | | caffeic acid | geroprotector;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| coniferyl alcohol | | guaiacols;
phenylpropanoid | animal metabolite;
monolignol;
mouse metabolite;
pheromone;
plant metabolite;
volatile oil component | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| raphanusamic acid | | thiazolidinemonocarboxylic acid | Arabidopsis thaliana metabolite;
mouse metabolite;
xenobiotic metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| glutaryl-coenzyme a | | glutaryl-CoAs | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| thromboxane a2 | | epoxy monocarboxylic acid;
thromboxanes A | mouse metabolite | 1980 | 2017 | 32.9 | medium | 45 | 243 | 196 | 43 | 10 | 0 |
| arachidonic acid 5-hydroperoxide | | 5-HPETE | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| arachidonic acid omega-9 hydroperoxide | | HPETE | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid, (s)-(e,z,z,z)-isomer | | 15-HPETE | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| alpha-linolenic acid | | linolenic acid;
omega-3 fatty acid | micronutrient;
mouse metabolite;
nutraceutical | 1984 | 2007 | 30.0 | low | 0 | 2 | 6 | 1 | 0 | 0 |
| 1-palmitoyl-2-oleoyl-sn-glycerol | | 1,2-diacyl-sn-glycerol;
1-palmitoyl-2-oleoylglycerol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| epoprostenol | | prostaglandins I | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 11,12-dihydroxyeicosatrienoic acid | | DHET | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 14,15-dihydroxyeicosatrienoic acid | | DHET;
diol;
secondary allylic alcohol | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5,6-epoxy-8,11,14-eicosatrienoic acid | | EET | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 8,9-epoxyeicosatrienoic acid | | EET | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-palmitoyl-2-oleoylphosphatidylethanolamine, (z & r)-isomer | | 1,2-diacyl-sn-glycero-3-phosphoethanolamine;
phosphatidylethanolamine 34:1 zwitterion;
phosphatidylethanolamine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| sphingosine 1-phosphate | | sphingoid 1-phosphate | mouse metabolite;
signalling molecule;
sphingosine-1-phosphate receptor agonist;
T-cell proliferation inhibitor;
vasodilator agent | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholesteryl oleate | | CE(18:1);
cholesteryl octadec-9-enoate | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| stearidonic acid | | long-chain fatty acid;
octadecatetraenoic acid;
omega-3 fatty acid | Daphnia galeata metabolite;
mouse metabolite;
plant metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| trilinolein | | 1,2-diacyl-3-linoleoylglycerol;
1,3-diacyl-2-linoleoylglycerol;
linoleoyl containing 1,2,3-triacyl-sn-glycerol;
TG(18:2/18:2/18:2);
triglyceride | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dimyristoylphosphatidylcholine | | 1,2-diacyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 28:0;
tetradecanoate ester | antigen;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| monodehydroascorbate | | organic radical | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| oleoyl-coenzyme a | | octadecenoyl-CoA | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| vitamin a2 | | retinoid;
vitamin A | human xenobiotic metabolite;
marine xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1,2-dioleoylphosphatidylserine | | phosphatidylserine(18:1/18:1) | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5-hydroxy-6,8,11,14,17-eicosapentaenoic acid | | HEPE | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-stearoyl-2-linoleoylphosphatidylcholine | | phosphatidylcholine 36:2 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-stearoyl-2-linoleoyl-sn-glycerol | | 1,2-diacyl-sn-glycerol;
diacylglycerol 36:2 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine | | phosphatidylcholine 38:6 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 13(S)-HODE | | HODE | antineoplastic agent;
human xenobiotic metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-stearoyl-2-oleoyl-sn-glycerol | | 1,2-diacyl-sn-glycerol;
1-stearoyl-2-oleoylglycerol;
diacylglycerol 36:1 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 1-palmitoyl-2-palmitoleoyl-sn-glycero-3-phosphocholine | | 1-acyl-2-palmitoleoyl-sn-glycero-3-phosphocholine;
phosphatidylcholine 32:1 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 13-oxo-9,11-octadecadienoic acid | | 13-oxo-9,11-octadecadienoic acid | metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-stearoylsphingomyelin | | sphingomyelin 36:1;
sphingomyelin d18:1 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cholesteryl arachidonate | | cholesteryl icosatetraenoate | antibacterial agent;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| acryloyl-coenzyme a | | 2-enoyl-CoA;
monounsaturated fatty acyl-CoA | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| samarium | | sphingomyelin d18:1/16:0 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| n-palmitoylgalactosylsphingosine | | HexCer(d18:1/16:0);
N-acyl-beta-D-galactosylsphingosine | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| s-tetradecanoyl-coenzyme a | | 11,12-saturated fatty acyl-CoA;
long-chain fatty acyl-CoA | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| prosomatostatin | | heterodetic cyclic peptide;
peptide hormone | fungal metabolite;
mouse metabolite;
rat metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| phosphatidylcholines | | phosphatidylcholine 40:6 | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| cyclosporine | | keto-disaccharide | mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| g(m3) ganglioside | | alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide;
sialodiosylceramide;
sialotriaosylceramide | mouse metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| diguanosine tetraphosphate | | guanosine 5'-phosphate;
purine ribonucleoside 5'-tetraphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2'-deoxyguanosine 5'-phosphate | | deoxyguanosine phosphate;
guanyl deoxyribonucleotide;
purine 2'-deoxyribonucleoside 5'-monophosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydrofolate | | dihydrofolic acids | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| dihydroneopterin triphosphate | | dihydropterin;
neopterins;
pterin phosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 2'-deoxyinosine triphosphate | | deoxyinosine phosphate;
purine 2'-deoxyribonucleoside 5'-triphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| guanosine diphosphate | | guanosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate | Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| gdp-4-keto-6-deoxymannose | | GDP-sugar | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| guanosine pentaphosphate | | guanosine 5'-phosphate;
guanosine bisphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| guanosine monophosphate | | guanosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate | biomarker;
Escherichia coli metabolite;
metabolite;
mouse metabolite | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| guanosine triphosphate | | guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate | Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor | 1984 | 2000 | 32.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| guanosine tetraphosphate | | guanosine bisphosphate | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| leucovorin | | formyltetrahydrofolic acid | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 5,10-methenyltetrahydrofolate | | methylenetetrahydrofolic acid | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| 10-formyltetrahydrofolate | | formyltetrahydrofolic acid | Escherichia coli metabolite;
mouse metabolite | 0 | 0 | | low | 0 | 0 | 0 | 0 | 0 | 0 |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|
| acetylcarnitine | | O-acylcarnitine | human metabolite | 1990 | 1996 | 30.7 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| protocatechuic acid | | catechols;
dihydroxybenzoic acid | antineoplastic agent;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor;
human xenobiotic metabolite;
plant metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| acetoacetic acid | | 3-oxo fatty acid;
ketone body | metabolite | 1996 | 1996 | 28.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| acetic acid | | monocarboxylic acid | antimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent | 1999 | 2005 | 22.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| acetaldehyde | | aldehyde | carcinogenic agent;
EC 3.5.1.4 (amidase) inhibitor;
electron acceptor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
mutagen;
oxidising agent;
Saccharomyces cerevisiae metabolite;
teratogenic agent | 1987 | 1993 | 35.5 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| adenine | | 6-aminopurines;
purine nucleobase | Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1987 | 1989 | 36.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| allantoin | | imidazolidine-2,4-dione;
ureas | Escherichia coli metabolite;
human metabolite;
Saccharomyces cerevisiae metabolite;
vulnerary | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ammonium hydroxide | | azane;
gas molecular entity;
mononuclear parent hydride | EC 3.5.1.4 (amidase) inhibitor;
metabolite;
mouse metabolite;
neurotoxin;
NMR chemical shift reference compound;
nucleophilic reagent;
refrigerant | 1988 | 2001 | 29.0 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| arsenic acid | | arsenic oxoacid | Escherichia coli metabolite | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| quinacrine | | acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound | antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor | 1983 | 1994 | 37.2 | low | 0 | 8 | 2 | 0 | 0 | 0 |
| benzoic acid | | benzoic acids | algal metabolite;
antimicrobial food preservative;
drug allergen;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.1.1.3 (triacylglycerol lipase) inhibitor;
human xenobiotic metabolite;
plant metabolite | 1986 | 1991 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| bromide | | halide anion;
monoatomic bromine | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| butyric acid | | fatty acid 4:0;
straight-chain saturated fatty acid | human urinary metabolite;
Mycoplasma genitalium metabolite | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| carbon monoxide | | carbon oxide;
gas molecular entity;
one-carbon compound | biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent | 1987 | 2008 | 29.0 | low | 0 | 2 | 1 | 1 | 0 | 0 |
| carnitine | | amino-acid betaine | human metabolite;
mouse metabolite | 1990 | 1994 | 32.3 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| methane | | alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound | bacterial metabolite;
fossil fuel;
greenhouse gas | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| choline | | cholines | allergen;
Daphnia magna metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
neurotransmitter;
nutrient;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| chlorine | | halide anion;
monoatomic chlorine | cofactor;
Escherichia coli metabolite;
human metabolite | 1983 | 2014 | 29.4 | low | 3 | 6 | 7 | 2 | 1 | 0 |
| hydrochloric acid | | chlorine molecular entity;
gas molecular entity;
hydrogen halide;
mononuclear parent hydride | mouse metabolite | 1984 | 2004 | 31.8 | low | 0 | 4 | 0 | 2 | 0 | 0 |
| salicylic acid | | monohydroxybenzoic acid | algal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite | 1983 | 2012 | 31.7 | low | 1 | 5 | 5 | 0 | 1 | 0 |
| phloroglucinol | | benzenetriol;
phenolic donor | algal metabolite | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| gallic acid | | trihydroxybenzoic acid | antineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite | 1981 | 1996 | 36.0 | low | 0 | 7 | 5 | 0 | 0 | 0 |
| 3-hydroxybutyric acid | | (omega-1)-hydroxy fatty acid;
3-hydroxy monocarboxylic acid;
hydroxybutyric acid | human metabolite | 1996 | 1996 | 28.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| n(1)-methylnicotinamide | | pyridinium ion | algal metabolite;
anti-inflammatory agent;
human urinary metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 2015 | 2016 | 8.5 | low | 0 | 0 | 0 | 0 | 2 | 0 |
| guaiacol | | guaiacols | disinfectant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
expectorant;
plant metabolite | 1984 | 1990 | 37.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| creatine | | glycine derivative;
guanidines;
zwitterion | geroprotector;
human metabolite;
mouse metabolite;
neuroprotective agent;
nutraceutical | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| lactic acid | | 2-hydroxy monocarboxylic acid | algal metabolite;
Daphnia magna metabolite | 1982 | 2009 | 32.2 | low | 3 | 7 | 10 | 1 | 0 | 0 |
| dimethyl sulfoxide | | sulfoxide;
volatile organic compound | alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger | 1983 | 2005 | 30.7 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| glycine | | alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical | 1983 | 2004 | 30.6 | low | 0 | 2 | 2 | 1 | 0 | 0 |
| glycerol | | alditol;
triol | algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent | 1981 | 1993 | 37.6 | low | 0 | 6 | 1 | 0 | 0 | 0 |
| hydrogen carbonate | | carbon oxoanion | cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1984 | 1994 | 35.9 | low | 0 | 6 | 2 | 0 | 0 | 0 |
| dalteparin | | | | 2001 | 2006 | 20.5 | low | 1 | 0 | 0 | 2 | 0 | 0 |
| histamine | | aralkylamino compound;
imidazoles | human metabolite;
mouse metabolite;
neurotransmitter | 1981 | 2013 | 33.8 | low | 1 | 27 | 16 | 4 | 1 | 0 |
| hydrogen | | elemental hydrogen;
elemental molecule;
gas molecular entity | antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| imidazole | | imidazole | | 1981 | 1989 | 38.9 | low | 0 | 11 | 0 | 0 | 0 | 0 |
| methanol | | alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound | amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| inositol | | cyclitol;
hexol | | 1984 | 1996 | 33.2 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| melatonin | | acetamides;
tryptamines | anticonvulsant;
central nervous system depressant;
geroprotector;
hormone;
human metabolite;
immunological adjuvant;
mouse metabolite;
radical scavenger | 1986 | 2006 | 28.0 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| niacinamide | | pyridine alkaloid;
pyridinecarboxamide;
vitamin B3 | anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor | 2007 | 2016 | 11.3 | low | 0 | 0 | 0 | 1 | 2 | 0 |
| niacin | | pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3 | antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent | 1987 | 2002 | 29.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| nitrates | | monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species | | 1985 | 2018 | 22.6 | low | 5 | 2 | 10 | 18 | 3 | 0 |
| nitrites | | monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species | human metabolite | 1994 | 2018 | 21.8 | low | 3 | 0 | 15 | 17 | 3 | 0 |
| nitrous oxide | | gas molecular entity;
nitrogen oxide | analgesic;
bacterial metabolite;
food packaging gas;
food propellant;
general anaesthetic;
greenhouse gas;
inhalation anaesthetic;
NMDA receptor antagonist;
raising agent;
refrigerant;
vasodilator agent | 1986 | 1986 | 38.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| orotic acid | | pyrimidinemonocarboxylic acid | Escherichia coli metabolite;
metabolite;
mouse metabolite | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 4-aminobenzoic acid | | aminobenzoic acid;
aromatic amino-acid zwitterion | allergen;
Escherichia coli metabolite;
plant metabolite | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| palmitic acid | | long-chain fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor;
plant metabolite | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| phenol | | phenols | antiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 1-propanol | | propan-1-ols;
short-chain primary fatty alcohol | metabolite;
protic solvent | 1993 | 1998 | 29.0 | low | 1 | 0 | 3 | 0 | 0 | 0 |
| propionic acid | | saturated fatty acid;
short-chain fatty acid | antifungal drug | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| pyridoxine | | hydroxymethylpyridine;
methylpyridines;
monohydroxypyridine;
vitamin B6 | cofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| pyruvic acid | | 2-oxo monocarboxylic acid | cofactor;
fundamental metabolite | 1991 | 1996 | 30.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| sulfites | | divalent inorganic anion;
sulfur oxide;
sulfur oxoanion | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| succinic acid | | alpha,omega-dicarboxylic acid;
C4-dicarboxylic acid | anti-ulcer drug;
fundamental metabolite;
micronutrient;
nutraceutical;
radiation protective agent | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| taurine | | amino sulfonic acid;
zwitterion | antioxidant;
Escherichia coli metabolite;
glycine receptor agonist;
human metabolite;
mouse metabolite;
nutrient;
radical scavenger;
Saccharomyces cerevisiae metabolite | 1987 | 1998 | 31.8 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| uric acid | | uric acid | Escherichia coli metabolite;
human metabolite;
mouse metabolite | 1983 | 2008 | 31.4 | low | 2 | 3 | 3 | 1 | 0 | 0 |
| urea | | isourea;
monocarboxylic acid amide;
one-carbon compound | Daphnia magna metabolite;
Escherichia coli metabolite;
fertilizer;
flour treatment agent;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1993 | 1998 | 28.3 | low | 1 | 0 | 3 | 0 | 0 | 0 |
| xanthine | | xanthine | Saccharomyces cerevisiae metabolite | 1989 | 1995 | 32.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| gallopamil | | benzenes;
organic amino compound | | 1988 | 1996 | 32.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| 1,2-dimethylhydrazine | | hydrazines | alkylating agent;
carcinogenic agent | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1,2-dioctanoylglycerol | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1-anilino-8-naphthalenesulfonate | | aminonaphthalene;
naphthalenesulfonic acid | fluorescent probe | 1992 | 1997 | 29.8 | low | 0 | 0 | 6 | 0 | 0 | 0 |
| 14,15-epoxy-5,8,11-eicosatrienoic acid | | long-chain fatty acid | | 1989 | 1997 | 31.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| n-(3-(aminomethyl)benzyl)acetamidine | | aralkylamine;
carboxamidine;
primary amino compound | angiogenesis inhibitor;
EC 1.14.13.39 (nitric oxide synthase) inhibitor;
geroprotector | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 17-octadecynoic acid | | acetylenic fatty acid;
long-chain fatty acid;
monounsaturated fatty acid;
terminal acetylenic compound | EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor;
EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor;
P450 inhibitor | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one | | oxadiazoloquinoxaline | EC 4.6.1.2 (guanylate cyclase) inhibitor | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| mercaptoethanol | | alkanethiol;
primary alcohol | geroprotector | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| enprofylline | | oxopurine | anti-arrhythmia drug;
anti-asthmatic drug;
bronchodilator agent;
non-steroidal anti-inflammatory drug | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 4-aminopyridine | | aminopyridine;
aromatic amine | avicide;
orphan drug;
potassium channel blocker | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| phenytoin | | imidazolidine-2,4-dione | anticonvulsant;
drug allergen;
sodium channel blocker;
teratogenic agent | 1982 | 1992 | 37.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| 5,8,11,14-eicosatetraynoic acid | | long-chain fatty acid | | 1984 | 1988 | 38.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| 5-carboxamidotryptamine | | tryptamines | | 2001 | 2004 | 21.5 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| hydroxyindoleacetic acid | | indole-3-acetic acids | drug metabolite;
human metabolite;
mouse metabolite | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 7-nitroindazole | | | | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| 8-phenyltheophylline | | | | 1987 | 1996 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| oxyquinoline | | monohydroxyquinoline | antibacterial agent;
antifungal agrochemical;
antiseptic drug;
iron chelator | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| aa 861 | | 1,4-benzoquinones;
acetylenic compound;
primary alcohol | EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor | 1986 | 2003 | 30.5 | low | 0 | 2 | 3 | 1 | 0 | 0 |
| acetaminophen | | acetamides;
phenols | antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic | 1981 | 2015 | 29.1 | low | 4 | 5 | 5 | 4 | 1 | 0 |
| acetazolamide | | monocarboxylic acid amide;
sulfonamide;
thiadiazoles | anticonvulsant;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| alprazolam | | organochlorine compound;
triazolobenzodiazepine | anticonvulsant;
anxiolytic drug;
GABA agonist;
muscle relaxant;
sedative;
xenobiotic | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| aluminum fluoride | | aluminium coordination entity | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| am 251 | | amidopiperidine;
carbohydrazide;
dichlorobenzene;
organoiodine compound;
pyrazoles | antidepressant;
antineoplastic agent;
apoptosis inducer;
CB1 receptor antagonist | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| diatrizoic acid | | acetamides;
benzoic acids;
organoiodine compound | environmental contaminant;
radioopaque medium;
xenobiotic | 1985 | 1986 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| aminoglutethimide | | dicarboximide;
piperidones;
substituted aniline | adrenergic agent;
anticonvulsant;
antineoplastic agent;
EC 1.14.14.14 (aromatase) inhibitor | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| pimagedine | | guanidines;
one-carbon compound | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
EC 1.4.3.4 (monoamine oxidase) inhibitor | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| p-aminohippuric acid | | N-acylglycine | Daphnia magna metabolite | 1984 | 2001 | 33.6 | low | 4 | 3 | 5 | 1 | 0 | 0 |
| ampyrone | | primary amino compound;
pyrazolone | antipyretic;
antirheumatic drug;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
marine xenobiotic metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| theophylline | | dimethylxanthine | adenosine receptor antagonist;
anti-asthmatic drug;
anti-inflammatory agent;
bronchodilator agent;
drug metabolite;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
fungal metabolite;
human blood serum metabolite;
immunomodulator;
muscle relaxant;
vasodilator agent | 1983 | 1997 | 35.0 | low | 0 | 6 | 3 | 0 | 0 | 0 |
| amlodipine | | dihydropyridine;
ethyl ester;
methyl ester;
monochlorobenzenes;
primary amino compound | antihypertensive agent;
calcium channel blocker;
vasodilator agent | 1995 | 1996 | 28.3 | low | 3 | 0 | 3 | 0 | 0 | 0 |
| antipyrine | | pyrazolone | antipyretic;
cyclooxygenase 3 inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic | 1986 | 2006 | 33.0 | low | 0 | 3 | 0 | 1 | 0 | 0 |
| apraclonidine | | dichlorobenzene;
guanidines;
imidazolines | alpha-adrenergic agonist;
antiglaucoma drug;
beta-adrenergic agonist;
diagnostic agent;
ophthalmology drug | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| arecoline | | enoate ester;
methyl ester;
pyridine alkaloid;
tetrahydropyridine | metabolite;
muscarinic agonist | 1991 | 1991 | 33.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| aristolochic acid i | | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin | 1996 | 2000 | 26.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| aristolochic acid i | | aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound | carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| aspirin | | benzoic acids;
phenyl acetates;
salicylates | anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent | 1980 | 2019 | 31.8 | low | 43 | 123 | 103 | 30 | 11 | 0 |
| astemizole | | benzimidazoles;
piperidines | anti-allergic agent;
anticoronaviral agent;
H1-receptor antagonist | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| atenolol | | ethanolamines;
monocarboxylic acid amide;
propanolamine | anti-arrhythmia drug;
antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
sympatholytic agent;
xenobiotic | 1984 | 1994 | 37.2 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| azathioprine | | aryl sulfide;
C-nitro compound;
imidazoles;
thiopurine | antimetabolite;
antineoplastic agent;
carcinogenic agent;
DNA synthesis inhibitor;
hepatotoxic agent;
immunosuppressive agent;
prodrug | 1987 | 2018 | 25.8 | low | 2 | 1 | 2 | 0 | 1 | 0 |
| azelastine | | monochlorobenzenes;
phthalazines;
tertiary amino compound | anti-allergic agent;
anti-asthmatic drug;
bronchodilator agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
H1-receptor antagonist;
platelet aggregation inhibitor | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| bay-k-8644 | | (trifluoromethyl)benzenes;
C-nitro compound;
dihydropyridine;
methyl ester | | 1995 | 2002 | 24.7 | low | 0 | 0 | 1 | 2 | 0 | 0 |
| bendroflumethiazide | | benzothiadiazine;
sulfonamide | antihypertensive agent;
diuretic | 1981 | 1996 | 35.5 | low | 1 | 1 | 1 | 0 | 0 | 0 |
| benzethonium | | alkylbenzene | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| benzo(a)pyrene | | ortho- and peri-fused polycyclic arene | carcinogenic agent;
mouse metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| bepridil | | pyrrolidines;
tertiary amine | anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent | 1994 | 1994 | 30.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| berberine | | alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound | antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker | 1991 | 2000 | 29.5 | low | 0 | 0 | 4 | 0 | 0 | 0 |
| beta-naphthoflavone | | extended flavonoid;
naphtho-gamma-pyrone;
organic heterotricyclic compound | aryl hydrocarbon receptor agonist | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| bethanechol | | carbamate ester;
quaternary ammonium ion | muscarinic agonist | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| bisindolylmaleimide i | | | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| seratrodast | | organic molecular entity | | 1990 | 1999 | 29.0 | low | 1 | 0 | 4 | 0 | 0 | 0 |
| bumetanide | | amino acid;
benzoic acids;
sulfonamide | diuretic;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor | 1988 | 1994 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| bupivacaine | | aromatic amide;
piperidinecarboxamide;
tertiary amino compound | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| caffeine | | purine alkaloid;
trimethylxanthine | adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic | 1988 | 2004 | 28.3 | low | 0 | 1 | 4 | 1 | 0 | 0 |
| verapamil | | aromatic ether;
nitrile;
polyether;
tertiary amino compound | | 1981 | 2006 | 34.6 | low | 2 | 16 | 10 | 1 | 0 | 0 |
| calmidazolium | | imidazolium ion | apoptosis inducer;
calmodulin antagonist | 1985 | 1985 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| camostat | | benzoate ester;
carboxylic ester;
diester;
guanidines;
tertiary carboxamide | anti-inflammatory agent;
anticoronaviral agent;
antifibrinolytic drug;
antihypertensive agent;
antineoplastic agent;
antiviral agent;
serine protease inhibitor | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| carprofen | | carbazoles;
organochlorine compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug;
photosensitizing agent | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| carvedilol | | carbazoles;
secondary alcohol;
secondary amino compound | alpha-adrenergic antagonist;
antihypertensive agent;
beta-adrenergic antagonist;
cardiovascular drug;
vasodilator agent | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| celecoxib | | organofluorine compound;
pyrazoles;
sulfonamide;
toluenes | cyclooxygenase 2 inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1998 | 2016 | 18.2 | low | 4 | 0 | 5 | 12 | 6 | 0 |
| celiprolol | | aromatic ketone | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cgs 15943 | | aromatic amine;
biaryl;
furans;
organochlorine compound;
primary amino compound;
quinazolines;
triazoloquinazoline | adenosine A1 receptor antagonist;
adenosine A2A receptor antagonist;
antineoplastic agent;
central nervous system stimulant | 1994 | 2014 | 20.0 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| chelerythrine | | benzophenanthridine alkaloid;
organic cation | antibacterial agent;
antineoplastic agent;
EC 2.7.11.13 (protein kinase C) inhibitor | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| chloroquine | | aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound | anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug | 1988 | 1992 | 34.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| chlorpheniramine | | monochlorobenzenes;
pyridines;
tertiary amino compound | anti-allergic agent;
antidepressant;
antipruritic drug;
H1-receptor antagonist;
histamine antagonist;
serotonin uptake inhibitor | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| chlorpropamide | | monochlorobenzenes;
N-sulfonylurea | hypoglycemic agent;
insulin secretagogue | 1981 | 1984 | 41.5 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| cilostamide | | quinolines | | 1989 | 1990 | 34.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| cilostazol | | lactam;
tetrazoles | anticoagulant;
bronchodilator agent;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
fibrin modulating drug;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent | 1990 | 1992 | 33.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| cimetidine | | aliphatic sulfide;
guanidines;
imidazoles;
nitrile | adjuvant;
analgesic;
anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor | 1984 | 1997 | 34.1 | low | 0 | 5 | 5 | 0 | 0 | 0 |
| ciprofloxacin | | aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion | antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| clonidine | | clonidine;
imidazoline | | 1984 | 1987 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| clotrimazole | | conazole antifungal drug;
imidazole antifungal drug;
imidazoles;
monochlorobenzenes | antiinfective agent;
environmental contaminant;
xenobiotic | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cyclandelate | | carboxylic ester;
secondary alcohol | vasodilator agent | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cyproheptadine | | piperidines;
tertiary amine | anti-allergic agent;
antipruritic drug;
gastrointestinal drug;
H1-receptor antagonist;
serotonergic antagonist | 1992 | 1994 | 31.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| dantrolene | | hydrazone;
imidazolidine-2,4-dione | muscle relaxant;
neuroprotective agent;
ryanodine receptor antagonist | 1985 | 1988 | 37.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| deferoxamine | | acyclic desferrioxamine | bacterial metabolite;
ferroptosis inhibitor;
iron chelator;
siderophore | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| eflornithine | | alpha-amino acid;
fluoroamino acid | trypanocidal drug | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| diazepam | | 1,4-benzodiazepinone;
organochlorine compound | anticonvulsant;
anxiolytic drug;
environmental contaminant;
sedative;
xenobiotic | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| diazoxide | | benzothiadiazine;
organochlorine compound;
sulfone | antihypertensive agent;
beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
diuretic;
K-ATP channel agonist;
sodium channel blocker;
sympathomimetic agent;
vasodilator agent | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| diclofenac | | amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound | antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic | 1985 | 2015 | 27.1 | low | 2 | 7 | 12 | 9 | 1 | 0 |
| diethylcarbamazine | | N-carbamoylpiperazine;
N-methylpiperazine | | 1985 | 2013 | 32.6 | low | 0 | 5 | 2 | 0 | 1 | 0 |
| pentetic acid | | pentacarboxylic acid | copper chelator | 1987 | 1988 | 36.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| dimethoate | | monocarboxylic acid amide;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| diphenhydramine | | ether;
tertiary amino compound | anti-allergic agent;
antidyskinesia agent;
antiemetic;
antiparkinson drug;
antipruritic drug;
antitussive;
H1-receptor antagonist;
local anaesthetic;
muscarinic antagonist;
oneirogen;
sedative | 1990 | 1994 | 32.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| dipyridamole | | piperidines;
pyrimidopyrimidine;
tertiary amino compound;
tetrol | adenosine phosphodiesterase inhibitor;
EC 3.5.4.4 (adenosine deaminase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent | 1981 | 1999 | 36.6 | low | 3 | 17 | 6 | 0 | 0 | 0 |
| disopyramide | | monocarboxylic acid amide;
pyridines;
tertiary amino compound | anti-arrhythmia drug | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| disulfiram | | organic disulfide;
organosulfur acaricide | angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| racemetirosine | | | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| thiorphan | | N-acyl-amino acid | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| dup 697 | | thiophenes | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| econazole | | dichlorobenzene;
ether;
imidazoles;
monochlorobenzenes | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| emodin | | trihydroxyanthraquinone | antineoplastic agent;
laxative;
plant metabolite;
tyrosine kinase inhibitor | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| enflurane | | ether;
organochlorine compound;
organofluorine compound | anaesthetic | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| epirizole | | aromatic ether | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| erythrosine | | | | 1984 | 2003 | 31.2 | low | 0 | 1 | 2 | 1 | 0 | 0 |
| ethacrynic acid | | aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid | EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic | 1981 | 1993 | 35.2 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| eicosapentaenoic acid ethyl ester | | | | 1982 | 1994 | 36.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| etodolac | | monocarboxylic acid;
organic heterotricyclic compound | antipyretic;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1985 | 2002 | 33.5 | low | 0 | 4 | 1 | 1 | 0 | 0 |
| famotidine | | 1,3-thiazoles;
guanidines;
sulfonamide | anti-ulcer drug;
H2-receptor antagonist;
P450 inhibitor | 2005 | 2007 | 18.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| felodipine | | dichlorobenzene;
dihydropyridine;
ethyl ester;
methyl ester | anti-arrhythmia drug;
antihypertensive agent;
calcium channel blocker;
vasodilator agent | 1993 | 1993 | 31.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| fentanyl | | anilide;
monocarboxylic acid amide;
piperidines | adjuvant;
anaesthesia adjuvant;
anaesthetic;
intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic | 1986 | 1986 | 38.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| fleroxacin | | difluorobenzene;
fluoroquinolone antibiotic;
monocarboxylic acid;
N-alkylpiperazine;
quinolines | antibacterial drug;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
topoisomerase IV inhibitor | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| flufenamic acid | | aromatic amino acid;
organofluorine compound | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| fluorouracil | | nucleobase analogue;
organofluorine compound | antimetabolite;
antineoplastic agent;
environmental contaminant;
immunosuppressive agent;
radiosensitizing agent;
xenobiotic | 1986 | 2007 | 27.2 | low | 0 | 1 | 2 | 1 | 0 | 0 |
| flurbiprofen | | fluorobiphenyl;
monocarboxylic acid | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1984 | 2017 | 25.1 | low | 3 | 2 | 3 | 1 | 2 | 0 |
| fp 83 | | organic molecular entity | | 2012 | 2017 | 9.5 | low | 2 | 0 | 0 | 0 | 2 | 0 |
| fomepizole | | pyrazoles | antidote;
EC 1.1.1.1 (alcohol dehydrogenase) inhibitor;
protective agent | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| furegrelate | | benzofurans | | 1986 | 1993 | 35.6 | low | 0 | 7 | 3 | 0 | 0 | 0 |
| furosemide | | chlorobenzoic acid;
furans;
sulfonamide | environmental contaminant;
loop diuretic;
xenobiotic | 1982 | 2008 | 33.6 | low | 7 | 17 | 9 | 3 | 0 | 0 |
| gabexate | | benzoate ester | | 1988 | 1993 | 33.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| gemfibrozil | | aromatic ether | antilipemic drug | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| gentamicin | | | | 1985 | 1998 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| glutaral | | dialdehyde | cross-linking reagent;
disinfectant;
fixative | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| glyburide | | monochlorobenzenes;
N-sulfonylurea | anti-arrhythmia drug;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor;
hypoglycemic agent | 1984 | 2014 | 28.8 | low | 0 | 3 | 1 | 1 | 1 | 0 |
| gossypol | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| guaifenesin | | methoxybenzenes | | 1986 | 1993 | 34.8 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| guanidine | | carboxamidine;
guanidines;
one-carbon compound | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1-(5-isoquinolinesulfonyl)-2-methylpiperazine | | isoquinolines;
N-sulfonylpiperazine | EC 2.7.11.13 (protein kinase C) inhibitor | 1989 | 1995 | 31.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| halothane | | haloalkane;
organobromine compound;
organochlorine compound;
organofluorine compound | inhalation anaesthetic | 1985 | 1988 | 37.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| hexahydrosiladifenidol | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| hexamethonium | | quaternary ammonium salt | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| hydralazine | | azaarene;
hydrazines;
ortho-fused heteroarene;
phthalazines | antihypertensive agent;
vasodilator agent | 1983 | 1985 | 39.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| hydrochlorothiazide | | benzothiadiazine;
organochlorine compound;
sulfonamide | antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic | 1983 | 1998 | 35.7 | low | 3 | 4 | 2 | 0 | 0 | 0 |
| hydroxyurea | | one-carbon compound;
ureas | antimetabolite;
antimitotic;
antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor;
genotoxin;
immunomodulator;
radical scavenger;
teratogenic agent | 1987 | 2016 | 23.7 | low | 0 | 1 | 1 | 0 | 1 | 0 |
| ibudilast | | pyrazolopyridine | | 1986 | 2012 | 25.0 | low | 0 | 1 | 0 | 0 | 1 | 0 |
| ibuprofen | | monocarboxylic acid | antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
radical scavenger;
xenobiotic | 1981 | 2010 | 34.8 | low | 9 | 54 | 20 | 4 | 0 | 0 |
| lidocaine | | benzenes;
monocarboxylic acid amide;
tertiary amino compound | anti-arrhythmia drug;
drug allergen;
environmental contaminant;
local anaesthetic;
xenobiotic | 1980 | 1999 | 33.8 | low | 1 | 4 | 4 | 0 | 0 | 0 |
| amrinone | | bipyridines | EC 3.1.4.* (phosphoric diester hydrolase) inhibitor | 1983 | 1986 | 39.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| indapamide | | indoles;
organochlorine compound;
sulfonamide | antihypertensive agent;
diuretic | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| indomethacin | | aromatic ether;
indole-3-acetic acids;
monochlorobenzenes;
N-acylindole | analgesic;
drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
gout suppressant;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite;
xenobiotic | 1980 | 2017 | 33.4 | low | 28 | 303 | 196 | 57 | 6 | 0 |
| indoprofen | | gamma-lactam;
isoindoles;
monocarboxylic acid | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 1-methyl-3-isobutylxanthine | | 3-isobutyl-1-methylxanthine | | 1981 | 2016 | 34.5 | low | 0 | 9 | 3 | 0 | 1 | 0 |
| isoflurane | | organofluorine compound | inhalation anaesthetic | 1987 | 2004 | 28.5 | low | 1 | 1 | 0 | 1 | 0 | 0 |
| 2-propanol | | secondary alcohol;
secondary fatty alcohol | protic solvent | 1984 | 1998 | 35.1 | low | 0 | 5 | 2 | 0 | 0 | 0 |
| isoproterenol | | catechols;
secondary alcohol;
secondary amino compound | beta-adrenergic agonist;
bronchodilator agent;
cardiotonic drug;
sympathomimetic agent | 1981 | 2007 | 35.2 | low | 0 | 17 | 10 | 2 | 0 | 0 |
| isradipine | | benzoxadiazole;
dihydropyridine;
isopropyl ester;
methyl ester | | 1991 | 1998 | 29.5 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| staurosporine aglycone | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ketanserin | | aromatic ketone;
organofluorine compound;
piperidines;
quinazolines | alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist | 1984 | 1991 | 36.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| ketoconazole | | dichlorobenzene;
dioxolane;
ether;
imidazoles;
N-acylpiperazine;
N-arylpiperazine | | 1984 | 2002 | 33.7 | low | 1 | 2 | 0 | 1 | 0 | 0 |
| ketoprofen | | benzophenones;
oxo monocarboxylic acid | antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic | 1990 | 1996 | 31.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| ketorolac | | amino acid;
aromatic ketone;
monocarboxylic acid;
pyrrolizines;
racemate | analgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ketotifen | | cyclic ketone;
olefinic compound;
organic heterotricyclic compound;
organosulfur heterocyclic compound;
piperidines;
tertiary amino compound | anti-asthmatic drug;
H1-receptor antagonist | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 3-phenyllactic acid | | 2-hydroxy monocarboxylic acid | human metabolite | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| labetalol | | benzamides;
benzenes;
phenols;
primary carboxamide;
salicylamides;
secondary alcohol;
secondary amino compound | | 1986 | 1986 | 38.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| lauric acid | | medium-chain fatty acid;
straight-chain saturated fatty acid | algal metabolite;
antibacterial agent;
plant metabolite | 1993 | 2013 | 21.0 | low | 1 | 0 | 1 | 0 | 1 | 0 |
| leflunomide | | (trifluoromethyl)benzenes;
isoxazoles;
monocarboxylic acid amide | antineoplastic agent;
antiparasitic agent;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
hepatotoxic agent;
immunosuppressive agent;
non-steroidal anti-inflammatory drug;
prodrug;
pyrimidine synthesis inhibitor;
tyrosine kinase inhibitor | 1999 | 2018 | 15.5 | low | 1 | 0 | 1 | 0 | 1 | 0 |
| losartan | | biphenylyltetrazole;
imidazoles | angiotensin receptor antagonist;
anti-arrhythmia drug;
antihypertensive agent;
endothelin receptor antagonist | 1994 | 2006 | 23.7 | low | 0 | 0 | 3 | 3 | 0 | 0 |
| loxoprofen | | cyclopentanones;
monocarboxylic acid | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ly 171883 | | acetophenones;
aromatic ether;
phenols;
tetrazoles | anti-asthmatic drug;
leukotriene antagonist | 1988 | 1990 | 35.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| 6-anilino-5,8-quinolinedione | | aminoquinoline;
aromatic amine;
p-quinones;
quinolone | antineoplastic agent;
EC 4.6.1.2 (guanylate cyclase) inhibitor | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| mechlorethamine | | nitrogen mustard;
organochlorine compound | alkylating agent | 1987 | 1999 | 29.0 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| meclofenamic acid | | aminobenzoic acid;
organochlorine compound;
secondary amino compound | analgesic;
anticonvulsant;
antineoplastic agent;
antipyretic;
antirheumatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug | 1981 | 2001 | 36.4 | low | 0 | 27 | 10 | 1 | 0 | 0 |
| mefenamic acid | | aminobenzoic acid;
secondary amino compound | analgesic;
antipyretic;
antirheumatic drug;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-steroidal anti-inflammatory drug;
xenobiotic | 1984 | 1985 | 39.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| mesalamine | | amino acid;
aromatic amine;
monocarboxylic acid;
monohydroxybenzoic acid;
phenols | non-steroidal anti-inflammatory drug | 1989 | 1997 | 31.2 | low | 0 | 1 | 5 | 0 | 0 | 0 |
| metaproterenol | | aralkylamino compound;
phenylethanolamines;
resorcinols;
secondary alcohol;
secondary amino compound | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| metformin | | guanidines | environmental contaminant;
geroprotector;
hypoglycemic agent;
xenobiotic | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| methoxyflurane | | ether;
organochlorine compound;
organofluorine compound | hepatotoxic agent;
inhalation anaesthetic;
nephrotoxic agent;
non-narcotic analgesic | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| metoclopramide | | benzamides;
monochlorobenzenes;
substituted aniline;
tertiary amino compound | antiemetic;
dopaminergic antagonist;
environmental contaminant;
gastrointestinal drug;
xenobiotic | 1989 | 1989 | 35.0 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| metoprolol | | aromatic ether;
propanolamine;
secondary alcohol;
secondary amino compound | antihypertensive agent;
beta-adrenergic antagonist;
environmental contaminant;
geroprotector;
xenobiotic | 1986 | 1999 | 30.8 | low | 3 | 1 | 5 | 0 | 0 | 0 |
| metyrapone | | aromatic ketone | antimetabolite;
diagnostic agent;
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| mexiletine | | aromatic ether;
primary amino compound | anti-arrhythmia drug | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| miconazole | | dichlorobenzene;
ether;
imidazoles | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| midazolam | | imidazobenzodiazepine;
monofluorobenzenes;
organochlorine compound | anticonvulsant;
antineoplastic agent;
anxiolytic drug;
apoptosis inducer;
central nervous system depressant;
GABAA receptor agonist;
general anaesthetic;
muscle relaxant;
sedative | 2000 | 2012 | 18.0 | low | 2 | 0 | 1 | 0 | 1 | 0 |
| milrinone | | bipyridines;
nitrile;
pyridone | cardiotonic drug;
EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor;
platelet aggregation inhibitor;
vasodilator agent | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| minoxidil | | dialkylarylamine;
tertiary amino compound | | 1988 | 1994 | 34.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| mofezolac | | methoxybenzenes | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| molsidomine | | ethyl ester;
morpholines;
oxadiazole;
zwitterion | antioxidant;
apoptosis inhibitor;
cardioprotective agent;
nitric oxide donor;
vasodilator agent | 1983 | 2003 | 28.6 | low | 0 | 1 | 5 | 2 | 0 | 0 |
| n-(6-aminohexyl)-1-naphthalenesulfonamide | | naphthalenes;
sulfonic acid derivative | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| ethylmaleimide | | maleimides | anticoronaviral agent;
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.1.1 (hexokinase) inhibitor | 1980 | 1991 | 37.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| apnea | | purine nucleoside | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nabumetone | | methoxynaphthalene;
methyl ketone | cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug | 1987 | 1999 | 30.6 | low | 1 | 1 | 6 | 0 | 0 | 0 |
| nafamostat | | benzoic acids;
guanidines | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nafronyl | | naphthalenes | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nicardipine | | benzenes;
C-nitro compound;
diester;
dihydropyridine;
methyl ester;
tertiary amino compound | | 1986 | 1997 | 33.2 | low | 1 | 3 | 3 | 0 | 0 | 0 |
| niceritrol | | organic molecular entity | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| nifedipine | | C-nitro compound;
dihydropyridine;
methyl ester | calcium channel blocker;
human metabolite;
tocolytic agent;
vasodilator agent | 1982 | 2004 | 33.0 | low | 3 | 11 | 14 | 2 | 0 | 0 |
| niflumic acid | | aromatic carboxylic acid;
pyridines | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| nilvadipine | | dihydropyridine;
isopropyl ester;
methyl ester;
nitrile | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nimesulide | | aromatic ether;
C-nitro compound;
sulfonamide | cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug | 1996 | 2008 | 23.0 | low | 4 | 0 | 4 | 6 | 0 | 0 |
| nimodipine | | 2-methoxyethyl ester;
C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
isopropyl ester | antihypertensive agent;
calcium channel blocker;
cardiovascular drug;
vasodilator agent | 1985 | 1998 | 34.4 | low | 0 | 4 | 3 | 0 | 0 | 0 |
| nisoldipine | | C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
methyl ester | | 1985 | 1997 | 34.4 | low | 1 | 2 | 3 | 0 | 0 | 0 |
| nitrendipine | | C-nitro compound;
dicarboxylic acids and O-substituted derivatives;
diester;
dihydropyridine;
ethyl ester;
methyl ester | antihypertensive agent;
calcium channel blocker;
geroprotector;
vasodilator agent | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nitroglycerin | | nitroglycerol | explosive;
muscle relaxant;
nitric oxide donor;
prodrug;
tocolytic agent;
vasodilator agent;
xenobiotic | 1982 | 1999 | 35.4 | low | 0 | 11 | 6 | 0 | 0 | 0 |
| nizofenone | | benzophenones | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | | aromatic ether;
C-nitro compound;
sulfonamide | antineoplastic agent;
cyclooxygenase 2 inhibitor | 1993 | 2009 | 22.7 | low | 0 | 0 | 19 | 22 | 0 | 0 |
| nylidrin | | alkylbenzene | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ofloxacin | | 3-oxo monocarboxylic acid;
N-arylpiperazine;
N-methylpiperazine;
organofluorine compound;
oxazinoquinoline | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| omeprazole | | aromatic ether;
benzimidazoles;
pyridines;
sulfoxide | | 1992 | 2015 | 22.7 | low | 0 | 0 | 2 | 0 | 1 | 0 |
| oxonic acid | | 1,3,5-triazines;
monocarboxylic acid | | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| oxidopamine | | benzenetriol;
catecholamine;
primary amino compound | drug metabolite;
human metabolite;
neurotoxin | 1985 | 1992 | 35.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| oxyphenbutazone | | phenols;
pyrazolidines | antimicrobial agent;
antineoplastic agent;
antipyretic;
drug metabolite;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic metabolite | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| papaverine | | benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines | antispasmodic drug;
vasodilator agent | 1984 | 1995 | 34.4 | low | 0 | 3 | 4 | 0 | 0 | 0 |
| pd 98059 | | aromatic amine;
monomethoxyflavone | EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector | 1999 | 2006 | 21.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| pentobarbital | | barbiturates | GABAA receptor agonist | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| pentoxifylline | | oxopurine | | 1984 | 1997 | 32.4 | low | 1 | 5 | 9 | 0 | 0 | 0 |
| phenoxybenzamine | | aromatic amine | | 1982 | 1989 | 39.0 | low | 0 | 5 | 0 | 0 | 0 | 0 |
| oxophenylarsine | | arsine oxides | antineoplastic agent;
apoptosis inducer;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| phenylbutazone | | pyrazolidines | antirheumatic drug;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug | 1984 | 1996 | 35.6 | low | 0 | 5 | 2 | 0 | 0 | 0 |
| picotamide | | benzamides | | 1988 | 1997 | 31.5 | low | 1 | 1 | 1 | 0 | 0 | 0 |
| pimobendan | | benzimidazoles;
pyridazinone | cardiotonic drug;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| pindolol | | indoles;
secondary amine | antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist;
serotonergic antagonist;
vasodilator agent | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| pioglitazone | | aromatic ether;
pyridines;
thiazolidinediones | antidepressant;
cardioprotective agent;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hypoglycemic agent;
insulin-sensitizing drug;
PPARgamma agonist;
xenobiotic | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| pirenzepine | | pyridobenzodiazepine | anti-ulcer drug;
antispasmodic drug;
muscarinic antagonist | 1986 | 1986 | 38.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| piretanide | | aromatic ether | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| potassium chloride | | inorganic chloride;
inorganic potassium salt;
potassium salt | fertilizer | 1983 | 2002 | 32.6 | low | 0 | 2 | 2 | 1 | 0 | 0 |
| 4-aminobenzoic acid | | aminobenzoate;
aromatic amino-acid anion | Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| practolol | | acetamides;
ethanolamines;
propanolamine;
secondary alcohol;
secondary amino compound | anti-arrhythmia drug;
beta-adrenergic antagonist | 1983 | 1984 | 40.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| ono 1078 | | chromones | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| prazosin | | aromatic ether;
furans;
monocarboxylic acid amide;
piperazines;
quinazolines | alpha-adrenergic antagonist;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor | 1982 | 1994 | 36.6 | low | 0 | 5 | 3 | 0 | 0 | 0 |
| prilocaine | | amino acid amide;
monocarboxylic acid amide | anticonvulsant;
local anaesthetic | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| proadifen | | diarylmethane | | 1989 | 2003 | 28.0 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| probenecid | | benzoic acids;
sulfonamide | uricosuric drug | 1983 | 1986 | 39.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| proglumetacin | | aromatic ether;
benzamides;
carboxylic ester;
monochlorobenzenes;
N-acylindole;
N-alkylpiperazine | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| propofol | | phenols | anticonvulsant;
antiemetic;
intravenous anaesthetic;
radical scavenger;
sedative | 2003 | 2006 | 19.5 | low | 1 | 0 | 0 | 2 | 0 | 0 |
| propranolol | | naphthalenes;
propanolamine;
secondary amine | anti-arrhythmia drug;
antihypertensive agent;
anxiolytic drug;
beta-adrenergic antagonist;
environmental contaminant;
human blood serum metabolite;
vasodilator agent;
xenobiotic | 1981 | 2001 | 35.7 | low | 2 | 20 | 10 | 1 | 0 | 0 |
| propyl gallate | | trihydroxybenzoic acid | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| pyrilamine | | aromatic ether;
ethylenediamine derivative | H1-receptor antagonist | 1985 | 1997 | 33.2 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| rabeprazole | | benzimidazoles;
pyridines;
sulfoxide | anti-ulcer drug;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| opc 12759 | | secondary carboxamide | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| pf 5901 | | quinolines | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| ro 31-8220 | | imidothiocarbamic ester;
indoles;
maleimides | EC 2.7.11.13 (protein kinase C) inhibitor | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| rofecoxib | | butenolide;
sulfone | analgesic;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug | 1999 | 2007 | 21.0 | low | 3 | 0 | 1 | 6 | 0 | 0 |
| rolipram | | pyrrolidin-2-ones | antidepressant;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor | 2012 | 2012 | 12.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| s-methylisothiopseudouronium | | | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| sb 202190 | | imidazoles;
organofluorine compound;
phenols;
pyridines | apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| linsidomine | | morpholines | | 1992 | 2003 | 27.7 | low | 0 | 0 | 5 | 1 | 0 | 0 |
| sodium fluoride | | fluoride salt | mutagen | 1984 | 1990 | 35.4 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| ponalrestat | | phthalazines | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| stearic acid | | long-chain fatty acid;
saturated fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
human metabolite;
plant metabolite | 1984 | 2001 | 31.3 | low | 2 | 1 | 1 | 1 | 0 | 0 |
| sulfaphenazole | | primary amino compound;
pyrazoles;
substituted aniline;
sulfonamide antibiotic;
sulfonamide | antibacterial drug;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 1.14.13.67 (quinine 3-monooxygenase) inhibitor;
P450 inhibitor | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| sulfapyridine | | pyridines;
substituted aniline;
sulfonamide antibiotic;
sulfonamide | antiinfective agent;
dermatologic drug;
drug allergen;
environmental contaminant;
xenobiotic | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sulfasalazine | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sulfinpyrazone | | pyrazolidines;
sulfoxide | uricosuric drug | 1981 | 1985 | 41.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| suprofen | | aromatic ketone;
monocarboxylic acid;
thiophenes | antirheumatic drug;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug | 1987 | 2007 | 28.7 | low | 2 | 1 | 1 | 1 | 0 | 0 |
| theobromine | | dimethylxanthine | adenosine receptor antagonist;
bronchodilator agent;
food component;
human blood serum metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent | 1984 | 2001 | 35.0 | low | 2 | 5 | 1 | 1 | 0 | 0 |
| tiaprofenic acid | | aromatic ketone;
monocarboxylic acid;
thiophenes | drug allergen;
non-steroidal anti-inflammatory drug | 1985 | 1996 | 36.8 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| ticlopidine | | monochlorobenzenes;
thienopyridine | anticoagulant;
fibrin modulating drug;
hematologic agent;
P2Y12 receptor antagonist;
platelet aggregation inhibitor | 1984 | 2018 | 28.1 | low | 1 | 5 | 3 | 1 | 2 | 0 |
| 8-(n,n-diethylamino)octyl-3,4,5-trimethoxybenzoate | | trihydroxybenzoic acid | | 1981 | 1996 | 35.5 | low | 0 | 6 | 5 | 0 | 0 | 0 |
| tolazoline | | imidazoles | alpha-adrenergic antagonist;
antihypertensive agent;
vasodilator agent | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| tolmetin | | aromatic ketone;
monocarboxylic acid;
pyrroles | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug | 1988 | 1995 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| tranexamic acid | | amino acid | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| trapidil | | triazolopyrimidines | | 1981 | 1995 | 35.2 | low | 1 | 5 | 3 | 0 | 0 | 0 |
| trifluoperazine | | N-alkylpiperazine;
N-methylpiperazine;
organofluorine compound;
phenothiazines | antiemetic;
calmodulin antagonist;
dopaminergic antagonist;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor;
EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor;
phenothiazine antipsychotic drug | 1983 | 1991 | 37.8 | low | 0 | 7 | 2 | 0 | 0 | 0 |
| w 7 | | | | 1985 | 1991 | 37.5 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| ici 204,219 | | carbamate ester;
indoles;
N-sulfonylcarboxamide | anti-asthmatic agent;
leukotriene antagonist | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| zomepirac | | aromatic ketone;
monocarboxylic acid;
monochlorobenzenes;
pyrroles | cardiovascular drug;
non-steroidal anti-inflammatory drug | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| mitomycin | | mitomycin | alkylating agent;
antineoplastic agent | 1988 | 1992 | 34.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| corticosterone | | 11beta-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 1979 | 2017 | 31.5 | low | 0 | 4 | 5 | 0 | 1 | 0 |
| prednisolone | | 11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
drug metabolite;
environmental contaminant;
immunosuppressive agent;
xenobiotic | 1985 | 1997 | 34.5 | low | 0 | 4 | 2 | 0 | 0 | 0 |
| estriol | | 16alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-hydroxy steroid | estrogen;
human metabolite;
human xenobiotic metabolite;
mouse metabolite | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| reserpine | | alkaloid ester;
methyl ester;
yohimban alkaloid | adrenergic uptake inhibitor;
antihypertensive agent;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
first generation antipsychotic;
plant metabolite;
xenobiotic | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| phentolamine | | imidazoles;
phenols;
substituted aniline;
tertiary amino compound | alpha-adrenergic antagonist;
vasodilator agent | 1983 | 1996 | 34.8 | low | 0 | 4 | 5 | 0 | 0 | 0 |
| sorbitol | | glucitol | cathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent | 1989 | 1997 | 30.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| alloxan | | pyrimidone | hyperglycemic agent;
metabolite | 1992 | 2013 | 21.0 | low | 0 | 0 | 1 | 1 | 1 | 0 |
| thymidine | | pyrimidine 2'-deoxyribonucleoside | Escherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite | 1987 | 1998 | 31.2 | low | 0 | 2 | 4 | 0 | 0 | 0 |
| hydroxyproline | | 4-hydroxyproline;
L-alpha-amino acid zwitterion | human metabolite;
mouse metabolite;
plant metabolite | 1983 | 1996 | 36.8 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| thyroxine | | 2-halophenol;
iodophenol;
L-phenylalanine derivative;
non-proteinogenic L-alpha-amino acid;
thyroxine zwitterion;
thyroxine | antithyroid drug;
human metabolite;
mouse metabolite;
thyroid hormone | 1985 | 1998 | 34.2 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| carbachol | | ammonium salt;
carbamate ester | cardiotonic drug;
miotic;
muscarinic agonist;
nicotinic acetylcholine receptor agonist;
non-narcotic analgesic | 1980 | 1998 | 36.5 | low | 0 | 4 | 2 | 0 | 0 | 0 |
| norethindrone acetate | | 3-oxo-Delta(4) steroid;
acetate ester;
terminal acetylenic compound | progestin;
synthetic oral contraceptive | 2000 | 2000 | 24.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| spironolactone | | 3-oxo-Delta(4) steroid;
oxaspiro compound;
steroid lactone;
thioester | aldosterone antagonist;
antihypertensive agent;
diuretic;
environmental contaminant;
xenobiotic | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| aldosterone | | 11beta-hydroxy steroid;
18-oxo steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid hormone;
mineralocorticoid;
primary alpha-hydroxy ketone;
steroid aldehyde | human metabolite;
mouse metabolite | 1983 | 2014 | 32.8 | low | 10 | 29 | 15 | 3 | 2 | 0 |
| penicillamine | | non-proteinogenic alpha-amino acid;
penicillamine | antirheumatic drug;
chelator;
copper chelator;
drug allergen | 1987 | 1996 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| lynestrenol | | steroid | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| prednisone | | 11-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | adrenergic agent;
anti-inflammatory drug;
antineoplastic agent;
immunosuppressive agent;
prodrug | 1984 | 2018 | 27.6 | low | 2 | 1 | 3 | 0 | 1 | 0 |
| estrone | | 17-oxo steroid;
3-hydroxy steroid;
phenolic steroid;
phenols | antineoplastic agent;
bone density conservation agent;
estrogen;
human metabolite;
mouse metabolite | 1981 | 1992 | 38.5 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| dehydroepiandrosterone | | 17-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
androstanoid | androgen;
human metabolite;
mouse metabolite | 1984 | 1995 | 34.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| penicillin g | | penicillin allergen;
penicillin | antibacterial drug;
drug allergen;
epitope | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| pentylenetetrazole | | organic heterobicyclic compound;
organonitrogen heterocyclic compound | | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| triiodothyronine | | 2-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine | human metabolite;
mouse metabolite;
thyroid hormone | 1985 | 1998 | 33.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| isoflurophate | | dialkyl phosphate | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| carbon tetrachloride | | chlorocarbon;
chloromethanes | hepatotoxic agent;
refrigerant | 1988 | 2014 | 23.5 | low | 0 | 1 | 1 | 1 | 1 | 0 |
| alanine | | alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid | EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite | 1988 | 1993 | 33.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| serine | | L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid;
serine zwitterion;
serine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| aspartic acid | | aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
mouse metabolite;
neurotransmitter | 1989 | 2012 | 25.0 | low | 0 | 1 | 1 | 0 | 1 | 0 |
| glutamine | | amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 2001 | 2009 | 19.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| lysine | | aspartate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
lysine;
organic molecular entity;
proteinogenic amino acid | algal metabolite;
anticonvulsant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1985 | 1998 | 33.0 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| cyanides | | pseudohalide anion | EC 1.9.3.1 (cytochrome c oxidase) inhibitor | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| physostigmine | | carbamate ester;
indole alkaloid | antidote to curare poisoning;
EC 3.1.1.8 (cholinesterase) inhibitor;
miotic | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sucrose | | glycosyl glycoside | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| sucrose | | glycosyl glycoside | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
sweetening agent | 1981 | 2002 | 32.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| ethinyl estradiol | | 17-hydroxy steroid;
3-hydroxy steroid;
terminal acetylenic compound | xenoestrogen | 1983 | 1999 | 32.0 | low | 2 | 1 | 5 | 0 | 0 | 0 |
| tubocurarine | | bisbenzylisoquinoline alkaloid | drug allergen;
muscle relaxant;
nicotinic antagonist | 1984 | 1990 | 37.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| aminopyrine | | pyrazolone;
tertiary amino compound | antipyretic;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic | 1985 | 2006 | 30.7 | low | 0 | 2 | 0 | 1 | 0 | 0 |
| puromycin aminonucleoside | | 3'-deoxyribonucleoside;
adenosines | | 1982 | 1991 | 37.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| adenosine diphosphate | | adenosine 5'-phosphate;
purine ribonucleoside 5'-diphosphate | fundamental metabolite;
human metabolite | 1980 | 2013 | 32.3 | low | 6 | 28 | 21 | 6 | 3 | 0 |
| galactose | | D-galactose;
galactopyranose | Escherichia coli metabolite;
mouse metabolite | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| carbostyril | | monohydroxyquinoline;
quinolone | bacterial xenobiotic metabolite | 1989 | 2000 | 31.2 | low | 0 | 1 | 4 | 0 | 0 | 0 |
| phenylephrine | | phenols;
phenylethanolamines;
secondary amino compound | alpha-adrenergic agonist;
cardiotonic drug;
mydriatic agent;
nasal decongestant;
protective agent;
sympathomimetic agent;
vasoconstrictor agent | 1982 | 2020 | 28.0 | low | 0 | 4 | 5 | 1 | 2 | 0 |
| edetic acid | | ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid | anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector | 1986 | 2013 | 24.5 | low | 0 | 1 | 0 | 0 | 1 | 0 |
| phenylethyl alcohol | | benzenes;
primary alcohol | Aspergillus metabolite;
fragrance;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| tyrosine | | amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine | EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical | 2011 | 2017 | 10.0 | low | 0 | 0 | 0 | 0 | 2 | 0 |
| cysteamine | | amine;
thiol | geroprotector;
human metabolite;
mouse metabolite;
radiation protective agent | 1986 | 1993 | 35.2 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| methoxamine | | amphetamines | alpha-adrenergic agonist;
antihypotensive agent | 1989 | 2003 | 27.7 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| adenosine monophosphate | | adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate | adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| methylene blue | | organic chloride salt | acid-base indicator;
antidepressant;
antimalarial;
antimicrobial agent;
antioxidant;
cardioprotective agent;
EC 1.4.3.4 (monoamine oxidase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 4.6.1.2 (guanylate cyclase) inhibitor;
fluorochrome;
histological dye;
neuroprotective agent;
physical tracer | 1986 | 2002 | 30.4 | low | 0 | 2 | 4 | 1 | 0 | 0 |
| leucine | | amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1993 | 1997 | 28.7 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| methacholine chloride | | quaternary ammonium salt | | 1988 | 1998 | 32.8 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| androstenedione | | 17-oxo steroid;
3-oxo-Delta(4) steroid;
androstanoid | androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite | 1985 | 1990 | 35.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| uridine triphosphate | | pyrimidine ribonucleoside 5'-triphosphate;
uridine 5'-phosphate | Escherichia coli metabolite;
mouse metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1,2-dipalmitoylphosphatidylcholine | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| desoxycorticosterone | | 20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
mineralocorticoid;
primary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 1985 | 1998 | 33.3 | low | 0 | 3 | 3 | 0 | 0 | 0 |
| colchicine | | alkaloid;
colchicine | anti-inflammatory agent;
gout suppressant;
mutagen | 1986 | 1991 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| strophanthidin | | 14beta-hydroxy steroid;
19-oxo steroid;
3beta-hydroxy steroid;
5beta-hydroxy steroid;
cardenolides;
steroid aldehyde | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cycloheximide | | antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol | anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor | 1980 | 1999 | 34.0 | low | 0 | 18 | 13 | 0 | 0 | 0 |
| egtazic acid | | diether;
tertiary amino compound;
tetracarboxylic acid | chelator | 1985 | 1996 | 33.3 | low | 0 | 3 | 3 | 0 | 0 | 0 |
| dimethyl sulfone | | sulfone | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| norethindrone | | 17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound;
tertiary alcohol | progestin;
synthetic oral contraceptive | 1984 | 2000 | 30.0 | low | 3 | 1 | 4 | 0 | 0 | 0 |
| tubercidin | | antibiotic antifungal agent;
N-glycosylpyrrolopyrimidine;
ribonucleoside | antimetabolite;
antineoplastic agent;
bacterial metabolite | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| mannitol | | mannitol | allergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent | 1991 | 2002 | 27.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| medroxyprogesterone acetate | | 20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
corticosteroid;
steroid ester | adjuvant;
androgen;
antineoplastic agent;
antioxidant;
female contraceptive drug;
inhibitor;
progestin;
synthetic oral contraceptive | 1985 | 2016 | 23.5 | low | 0 | 1 | 0 | 0 | 1 | 0 |
| valine | | L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine | algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| mestranol | | 17beta-hydroxy steroid;
aromatic ether;
terminal acetylenic compound | prodrug;
xenoestrogen | 1990 | 1992 | 33.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| tryptophan | | erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan | antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1981 | 2004 | 28.4 | low | 0 | 1 | 3 | 1 | 0 | 0 |
| n,n'-diphenyl-4-phenylenediamine | | N-substituted diamine;
secondary amino compound | antioxidant | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| arginine | | arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical | 1988 | 2006 | 29.6 | low | 2 | 1 | 32 | 3 | 0 | 0 |
| phosgene | | acyl chloride | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| tert-butylhydroperoxide | | alkyl hydroperoxide | antibacterial agent;
oxidising agent | 1983 | 1998 | 34.7 | low | 0 | 4 | 2 | 0 | 0 | 0 |
| phencyclidine | | benzenes;
piperidines | anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| tromethamine | | primary amino compound;
triol | buffer | 1981 | 1997 | 33.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| taurocholic acid | | amino sulfonic acid;
bile acid taurine conjugate | human metabolite | 1984 | 2009 | 30.5 | low | 0 | 5 | 7 | 2 | 0 | 0 |
| skatole | | methylindole | human metabolite;
mammalian metabolite | 1989 | 1993 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| methylprednisolone | | 6-methylprednisolone;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | adrenergic agent;
anti-inflammatory drug;
antiemetic;
environmental contaminant;
neuroprotective agent;
xenobiotic | 1981 | 2004 | 34.3 | low | 1 | 10 | 7 | 1 | 0 | 0 |
| isosorbide dinitrate | | glucitol derivative;
nitrate ester | nitric oxide donor;
vasodilator agent | 1984 | 1987 | 38.5 | low | 0 | 6 | 0 | 0 | 0 | 0 |
| thymol | | monoterpenoid;
phenols | volatile oil component | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| quinoxalines | | mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| phenidone | | | | 1991 | 2000 | 28.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| xanthenes | | xanthene | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| quinuclidines | | quinuclidines;
saturated organic heterobicyclic parent | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| pyrroles | | pyrrole;
secondary amine | | 2005 | 2008 | 17.0 | low | 0 | 0 | 0 | 5 | 0 | 0 |
| thiophenes | | mancude organic heteromonocyclic parent;
monocyclic heteroarene;
thiophenes;
volatile organic compound | non-polar solvent | 1984 | 2009 | 32.5 | low | 0 | 3 | 2 | 1 | 0 | 0 |
| 1-hexanol | | hexanol;
primary alcohol | alarm pheromone;
antibacterial agent;
fragrance;
plant metabolite | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ergotamine | | peptide ergot alkaloid | alpha-adrenergic agonist;
mycotoxin;
non-narcotic analgesic;
oxytocic;
serotonergic agonist;
vasoconstrictor agent | 1983 | 1986 | 39.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| methylergonovine | | ergoline alkaloid | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| framycetin | | aminoglycoside | allergen;
antibacterial drug;
Escherichia coli metabolite | 1990 | 1996 | 31.7 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| pyrazolanthrone | | anthrapyrazole;
aromatic ketone;
cyclic ketone | antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| diatrizoate meglumine | | monocarboxylic acid anion | radioopaque medium | 1985 | 1986 | 38.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| meglumine | | hexosamine;
secondary amino compound | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 2-naphthol | | naphthol | antinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| shikimic acid | | alpha,beta-unsaturated monocarboxylic acid;
cyclohexenecarboxylic acid;
hydroxy monocarboxylic acid | Escherichia coli metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 2002 | 2003 | 21.5 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| ethyl acetate | | acetate ester;
ethyl ester;
volatile organic compound | EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor;
metabolite;
polar aprotic solvent;
Saccharomyces cerevisiae metabolite | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| pregnenolone | | 20-oxo steroid;
3beta-hydroxy-Delta(5)-steroid;
C21-steroid | human metabolite;
mouse metabolite | 1983 | 1993 | 36.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| 20-alpha-dihydroprogesterone | | 20-hydroxypregn-4-en-3-one | human metabolite;
mouse metabolite | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| yohimbine | | methyl 17-hydroxy-20xi-yohimban-16-carboxylate | alpha-adrenergic antagonist;
dopamine receptor D2 antagonist;
serotonergic antagonist | 1982 | 2001 | 34.6 | low | 0 | 4 | 2 | 1 | 0 | 0 |
| potassium cyanide | | cyanide salt;
one-carbon compound;
potassium salt | EC 1.15.1.1 (superoxide dismutase) inhibitor;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
neurotoxin | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| dydrogesterone | | 20-oxo steroid;
3-oxo-Delta(4) steroid | progestin | 2006 | 2006 | 18.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| catechin | | catechin | antioxidant;
plant metabolite | 2001 | 2016 | 16.8 | low | 1 | 0 | 0 | 3 | 2 | 0 |
| quinazolines | | azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinazolines | | 1982 | 2014 | 31.3 | low | 0 | 4 | 1 | 1 | 1 | 0 |
| indazoles | | indazole | | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| cyclopentane | | cycloalkane;
cyclopentanes;
volatile organic compound | non-polar solvent | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| isoxazoles | | isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | | 1998 | 2018 | 18.8 | low | 2 | 0 | 2 | 1 | 1 | 0 |
| oxazoles | | 1,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| thiazoles | | 1,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | | 1999 | 2008 | 22.6 | low | 1 | 0 | 4 | 1 | 0 | 0 |
| pyrazines | | diazine;
pyrazines | Daphnia magna metabolite | 1990 | 2016 | 26.4 | low | 4 | 0 | 15 | 3 | 1 | 0 |
| triphenyltetrazolium | | organic cation | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| calcium gluconate | | calcium salt | nutraceutical | 1985 | 1990 | 36.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| muscarine | | monosaccharide | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| hydrazine | | azane;
hydrazines | EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor | 1985 | 2012 | 31.5 | low | 0 | 4 | 5 | 0 | 1 | 0 |
| monocrotaline | | pyrrolizidine alkaloid | | 1985 | 2016 | 25.6 | low | 0 | 4 | 5 | 2 | 3 | 0 |
| triflusal | | benzoic acids;
carboxylic ester;
salicylates | | 1985 | 1993 | 34.0 | low | 1 | 1 | 3 | 0 | 0 | 0 |
| methysergide | | ergoline alkaloid | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| phenylbenzoquinone | | | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| betamethasone | | 11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(1),Delta(4)-steroid;
fluorinated steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | anti-asthmatic agent;
anti-inflammatory drug;
immunosuppressive agent | 1981 | 1981 | 43.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| 5-methylpyrazole-3-carboxylic acid | | monocarboxylic acid;
pyrazoles | metabolite | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cyanamide | | nitrile;
one-carbon compound | EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cyproterone acetate | | 20-oxo steroid;
3-oxo-Delta(4) steroid;
acetate ester;
chlorinated steroid;
steroid ester | androgen antagonist;
geroprotector;
progestin | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| fluorobenzenes | | monofluorobenzenes | NMR chemical shift reference compound | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| rhein | | dihydroxyanthraquinone | | 1989 | 1989 | 35.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| dihydralazine | | phthalazines | | 1984 | 1996 | 35.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| sodium carbonate | | carbonate salt;
organic sodium salt | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| phorone | | dialkenyl ketone | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| alpha-aminopyridine | | | | 1983 | 1986 | 39.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| dihydroergotamine | | ergot alkaloid;
semisynthetic derivative | dopamine agonist;
non-narcotic analgesic;
serotonergic agonist;
sympatholytic agent;
vasoconstrictor agent | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| medroxyprogesterone | | 17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
tertiary alpha-hydroxy ketone | contraceptive drug;
progestin;
synthetic oral contraceptive | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| dihydrotestosterone | | 17beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid | androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| gluconic acid | | gluconic acid | chelator;
Penicillium metabolite | 1997 | 1997 | 27.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| copper gluconate | | organic molecular entity | | 1984 | 1997 | 35.0 | low | 1 | 2 | 2 | 0 | 0 | 0 |
| methoxyhydroxyphenylglycol | | methoxybenzenes;
phenols | | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| muscone | | | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| malondialdehyde | | dialdehyde | biomarker | 1984 | 2019 | 26.5 | low | 1 | 10 | 27 | 12 | 6 | 0 |
| 3-hexen-1-ol | | alkenyl alcohol;
homoallylic alcohol;
primary alcohol;
volatile organic compound | plant metabolite | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| myristic acid | | long-chain fatty acid;
straight-chain saturated fatty acid | algal metabolite;
Daphnia magna metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite | 1989 | 1993 | 33.0 | low | 1 | 1 | 1 | 0 | 0 | 0 |
| n-hexadecane | | long-chain alkane | non-polar solvent;
plant metabolite;
volatile oil component | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| trinitrobenzenesulfonic acid | | arenesulfonic acid;
C-nitro compound | epitope;
explosive;
reagent | 1990 | 2014 | 25.2 | low | 0 | 0 | 3 | 0 | 1 | 0 |
| 3-hydroxyflavone | | flavonols;
monohydroxyflavone | | 1993 | 1997 | 29.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| alpha-naphthoflavone | | extended flavonoid;
naphtho-gamma-pyrone;
organic heterotricyclic compound | aryl hydrocarbon receptor agonist;
aryl hydrocarbon receptor antagonist;
EC 1.14.14.14 (aromatase) inhibitor | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| erythromycin | | cyclic ketone;
erythromycin | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| dehydroepiandrosterone sulfate | | 17-oxo steroid;
steroid sulfate | EC 2.7.1.33 (pantothenate kinase) inhibitor;
human metabolite;
mouse metabolite | 1984 | 1995 | 34.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| chromonar | | coumarins | | 1982 | 1991 | 37.8 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| methylnitrosourea | | N-nitrosoureas | alkylating agent;
carcinogenic agent;
mutagen;
teratogenic agent | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| levonorgestrel | | 17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
terminal acetylenic compound | contraceptive drug;
female contraceptive drug;
progestin;
synthetic oral contraceptive | 1984 | 1995 | 34.2 | low | 1 | 2 | 3 | 0 | 0 | 0 |
| 2-cyclohexen-1-one | | cyclohexenone | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| dimethoxon | | organic thiophosphate;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| tetramethylpyrazine | | alkaloid;
pyrazines | antineoplastic agent;
apoptosis inhibitor;
bacterial metabolite;
neuroprotective agent;
platelet aggregation inhibitor;
vasodilator agent | 1991 | 2006 | 27.7 | low | 3 | 0 | 14 | 2 | 0 | 0 |
| 3,4-dihydroxyacetophenone | | acetophenones;
catechols;
dihydroxyacetophenone | metabolite | 1989 | 1993 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| durapatite | | | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| sodium hydroxide | | alkali metal hydroxide | | 1984 | 1986 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| d-alpha tocopherol | | alpha-tocopherol | algal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite | 1981 | 2004 | 33.2 | low | 3 | 13 | 18 | 1 | 0 | 0 |
| tocopherols | | | | 1981 | 1983 | 42.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| methyl tert-butyl ether | | ether | fuel additive;
metabolite;
non-polar solvent | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| paraquat | | organic cation | geroprotector;
herbicide | 1986 | 1992 | 35.0 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| amiloride | | aromatic amine;
guanidines;
organochlorine compound;
pyrazines | diuretic;
sodium channel blocker | 1986 | 1987 | 37.5 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| methylprednisolone hemisuccinate | | corticosteroid hormone;
hemisuccinate | | 1985 | 1990 | 36.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| c.i. direct blue 1 | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ethamsylate | | organosulfur compound;
sulfonic acid derivative | | 1986 | 1986 | 38.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| nitrohydroxyiodophenylacetate | | 2-nitrophenols;
organoiodine compound;
phenylacetic acids | antigen | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| fluorescein-5-isothiocyanate | | fluorescein isothiocyanate | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| sabinene | | thujene | plant metabolite | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| mannose | | D-aldohexose;
D-mannose;
mannopyranose | metabolite | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| tranylcypromine | | 2-phenylcyclopropan-1-amine | | 1981 | 2004 | 36.1 | low | 0 | 7 | 2 | 1 | 0 | 0 |
| carbonates | | carbon oxoanion | | 1987 | 1990 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| iodinated glycerol | | dioxolane | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| carbaspirin calcium | | | | 1996 | 1996 | 28.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| n-methylaspartate | | amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound | neurotransmitter agent | 1989 | 1999 | 29.8 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| 3-deazaadenosine | | | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| manganese | | elemental manganese;
manganese group element atom | Escherichia coli metabolite;
micronutrient | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| mercury | | elemental mercury;
zinc group element atom | neurotoxin | 2021 | 2021 | 3.0 | low | 0 | 0 | 0 | 0 | 0 | 1 |
| technetium | | manganese group element atom | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cadmium | | cadmium molecular entity;
zinc group element atom | | 1982 | 1998 | 33.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| vanadium | | elemental vanadium;
vanadium group element atom | micronutrient | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| magnesium sulfate | | magnesium salt;
metal sulfate;
organic magnesium salt | anaesthetic;
analgesic;
anti-arrhythmia drug;
anticonvulsant;
calcium channel blocker;
cardiovascular drug;
fertilizer;
tocolytic agent | 1983 | 2000 | 29.6 | low | 1 | 1 | 6 | 0 | 0 | 0 |
| mercuric chloride | | mercury coordination entity | sensitiser | 1987 | 1989 | 36.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| galactosamine | | D-galactosamine;
primary amino compound | toxin | 1987 | 1994 | 33.0 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| hypochlorous acid | | chlorine oxoacid;
reactive oxygen species | EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
human metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ferric chloride | | iron coordination entity | astringent;
Lewis acid | 2007 | 2014 | 14.0 | low | 0 | 0 | 0 | 2 | 1 | 0 |
| deuterium | | dihydrogen | | 1980 | 1996 | 38.4 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| fluorine | | diatomic fluorine;
gas molecular entity | NMR chemical shift reference compound | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| chlorine | | diatomic chlorine;
gas molecular entity | bleaching agent | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ozone | | elemental molecule;
gas molecular entity;
reactive oxygen species;
triatomic oxygen | antiseptic drug;
disinfectant;
electrophilic reagent;
greenhouse gas;
mutagen;
oxidising agent;
tracer | 1987 | 1997 | 32.2 | low | 1 | 1 | 3 | 0 | 0 | 0 |
| sodium selenite | | inorganic sodium salt;
selenite salt | nutraceutical | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| trolamine salicylate | | | | 1989 | 1998 | 30.0 | low | 3 | 1 | 3 | 0 | 0 | 0 |
| sodium tungstate(vi) | | inorganic sodium salt | reagent | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| apazone | | benzotriazines | non-steroidal anti-inflammatory drug;
uricosuric drug | 1993 | 1993 | 31.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| diacerein | | anthraquinone | | 1989 | 1989 | 35.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| tiletamine hydrochloride | | | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cromolyn sodium | | organic sodium salt | anti-asthmatic drug;
drug allergen | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| isosorbide-5-mononitrate | | glucitol derivative;
nitrate ester | nitric oxide donor;
vasodilator agent | 1985 | 1987 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| tetradecanoylphorbol acetate | | acetate ester;
diester;
phorbol ester;
tertiary alpha-hydroxy ketone;
tetradecanoate ester | antineoplastic agent;
apoptosis inducer;
carcinogenic agent;
mitogen;
plant metabolite;
protein kinase C agonist;
reactive oxygen species generator | 1980 | 1998 | 33.5 | low | 0 | 19 | 26 | 0 | 0 | 0 |
| fluorides | | halide anion;
monoatomic fluorine | | 1989 | 1995 | 32.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| clonixin | | aminopyridine;
organochlorine compound;
pyridinemonocarboxylic acid | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
platelet aggregation inhibitor;
vasodilator agent | 1982 | 1998 | 35.8 | low | 0 | 10 | 3 | 0 | 0 | 0 |
| dibenz(b,f)(1,4)oxazepine-10(11h)-carboxylic acid, 8-chloro-, 2-acetylhydrazide | | | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| iodine | | halide anion;
monoatomic iodine | human metabolite | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| phosphotyrosine | | L-tyrosine derivative;
non-proteinogenic L-alpha-amino acid;
O(4)-phosphotyrosine | Escherichia coli metabolite;
immunogen | 1996 | 1998 | 27.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| phenyl acetate | | benzenes;
phenyl acetates | | 1985 | 2016 | 29.9 | low | 0 | 4 | 3 | 1 | 1 | 0 |
| isothiuronium | | | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| proquazone | | pyrimidines | | 1985 | 2003 | 30.0 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| 4-methoxyamphetamine | | | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| du-21220 | | benzyl alcohols;
polyphenol;
secondary alcohol;
secondary amino compound | | 1983 | 1988 | 38.5 | low | 1 | 4 | 0 | 0 | 0 | 0 |
| 8-bromo cyclic adenosine monophosphate | | 3',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
organobromine compound | antidepressant;
protein kinase agonist | 1981 | 1989 | 38.2 | low | 0 | 5 | 0 | 0 | 0 | 0 |
| 6-methoxy-2-naphthylacetic acid | | methoxynaphthalene;
monocarboxylic acid | drug metabolite;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
xenobiotic metabolite | 1990 | 1992 | 33.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| transferrin | | | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| alkenes | | | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| glutamic acid | | glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical | 1989 | 1994 | 32.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| bis(4-methyl-1-homopiperazinylthiocarbonyl)disulfide | | | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| adenosine diphosphate ribose | | ADP-sugar | Escherichia coli metabolite;
mouse metabolite | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| timolol | | timolol | anti-arrhythmia drug;
antiglaucoma drug;
antihypertensive agent;
beta-adrenergic antagonist | 1984 | 1986 | 39.0 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| almitrine | | piperazines;
triamino-1,3,5-triazine | central nervous system stimulant | 1983 | 1988 | 38.2 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| vanadyl sulfate | | metal sulfate;
vanadium coordination entity | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| nicergoline | | organic heterotetracyclic compound;
organonitrogen heterocyclic compound | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| dehydrocorydalin | | alkaloid | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 3,4,3',4'-tetrachlorobiphenyl | | dichlorobenzene;
tetrachlorobiphenyl | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 3,4,5,3',4',5'-hexachlorobiphenyl | | hexachlorobiphenyl;
trichlorobenzene | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| substance p | | peptide | neurokinin-1 receptor agonist;
neurotransmitter;
vasodilator agent | 1987 | 2006 | 29.2 | low | 0 | 2 | 9 | 2 | 0 | 0 |
| imidazole-2-hydroxybenzoate | | | | 1992 | 1992 | 32.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| phorbol 12,13-dibutyrate | | butyrate ester;
phorbol ester;
tertiary alpha-hydroxy ketone | | 1991 | 2004 | 27.0 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| flunixin | | aminopyridine;
organofluorine compound;
pyridinemonocarboxylic acid | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| diltiazem | | 5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate | antihypertensive agent;
calcium channel blocker;
vasodilator agent | 1984 | 1997 | 34.0 | low | 1 | 5 | 8 | 0 | 0 | 0 |
| flunixin meglumine | | organoammonium salt | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1982 | 1997 | 37.2 | low | 0 | 9 | 1 | 0 | 0 | 0 |
| vecuronium bromide | | organic bromide salt;
quaternary ammonium salt | muscle relaxant;
neuromuscular agent;
nicotinic antagonist | 2000 | 2000 | 24.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| ng-nitroarginine methyl ester | | alpha-amino acid ester;
L-arginine derivative;
methyl ester;
N-nitro compound | EC 1.14.13.39 (nitric oxide synthase) inhibitor | 1992 | 2015 | 23.3 | low | 0 | 0 | 18 | 17 | 1 | 0 |
| dexibuprofen | | ibuprofen | non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| benoxaprofen | | 1,3-benzoxazoles;
monocarboxylic acid;
monochlorobenzenes | antipsoriatic;
antipyretic;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
hepatotoxic agent;
nephrotoxin;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
protein kinase C agonist | 1984 | 1993 | 36.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| desogestrel | | 17beta-hydroxy steroid;
terminal acetylenic compound | contraceptive drug;
progestin;
synthetic oral contraceptive | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| torsemide | | aminopyridine;
N-sulfonylurea;
secondary amino compound | antihypertensive agent;
loop diuretic | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| epirubicin | | aminoglycoside;
anthracycline antibiotic;
anthracycline;
deoxy hexoside;
monosaccharide derivative;
p-quinones;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | antimicrobial agent;
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| prenalterol | | aromatic ether | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| nufenoxole | | | | 1984 | 1984 | 40.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| enkephalin, methionine | | | | 1987 | 1996 | 32.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| nafazatrom | | | | 1983 | 1987 | 39.1 | medium | 1 | 10 | 0 | 0 | 0 | 0 |
| nitrosobis(2-oxopropyl)amine | | ketone;
nitrosamine | carcinogenic agent | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| orpanoxin | | | | 1993 | 1993 | 31.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
| captopril | | alkanethiol;
L-proline derivative;
N-acylpyrrolidine;
pyrrolidinemonocarboxylic acid | antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor | 1981 | 2015 | 33.4 | low | 4 | 23 | 15 | 2 | 1 | 0 |
| bopindolol | | aromatic ether;
benzoate ester;
methylindole;
secondary amino compound | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nicorandil | | nitrate ester;
pyridinecarboxamide | potassium channel opener;
vasodilator agent | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| bw-755c | | | | 1983 | 1991 | 38.1 | low | 0 | 6 | 1 | 0 | 0 | 0 |
| colforsin | | acetate ester;
cyclic ketone;
labdane diterpenoid;
organic heterotricyclic compound;
tertiary alpha-hydroxy ketone;
triol | adenylate cyclase agonist;
anti-HIV agent;
antihypertensive agent;
plant metabolite;
platelet aggregation inhibitor;
protein kinase A agonist | 1985 | 2004 | 32.7 | low | 0 | 6 | 4 | 1 | 0 | 0 |
| nedocromil | | dicarboxylic acid;
organic heterotricyclic compound | anti-allergic agent;
anti-asthmatic drug;
non-steroidal anti-inflammatory drug | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| daurisoline | | isoquinolines | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| pirazolac | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sulotroban | | | | 1985 | 1993 | 34.8 | low | 1 | 3 | 5 | 0 | 0 | 0 |
| fomesafen | | aromatic ether;
C-nitro compound;
monochlorobenzenes;
N-sulfonylcarboxamide;
organofluorine compound;
phenols | agrochemical;
EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| dazoxiben | | | | 1981 | 2002 | 37.4 | medium | 5 | 40 | 10 | 1 | 0 | 0 |
| lovastatin | | delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
polyketide;
statin (naturally occurring) | anticholesteremic drug;
antineoplastic agent;
Aspergillus metabolite;
prodrug | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| dazmegrel | | | | 1983 | 2001 | 36.0 | medium | 2 | 24 | 4 | 1 | 0 | 0 |
| bm 13505 | | | | 1989 | 1995 | 31.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| simvastatin | | delta-lactone;
fatty acid ester;
hexahydronaphthalenes;
statin (semi-synthetic) | EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor;
EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor;
ferroptosis inducer;
geroprotector;
prodrug | 2005 | 2008 | 17.0 | low | 2 | 0 | 0 | 3 | 0 | 0 |
| pravastatin | | 3-hydroxy carboxylic acid;
carbobicyclic compound;
carboxylic ester;
hydroxy monocarboxylic acid;
secondary alcohol;
statin (semi-synthetic) | anticholesteremic drug;
environmental contaminant;
metabolite;
xenobiotic | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| quinapril | | dicarboxylic acid monoester;
ethyl ester;
isoquinolines;
tertiary carboxamide | antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug | 1984 | 2002 | 29.2 | low | 1 | 1 | 2 | 1 | 0 | 0 |
| cicletanine | | organochlorine compound | | 1985 | 1999 | 33.6 | low | 2 | 7 | 6 | 0 | 0 | 0 |
| mifepristone | | 3-oxo-Delta(4) steroid;
acetylenic compound;
tertiary amino compound | abortifacient;
contraceptive drug;
hormone antagonist;
synthetic oral contraceptive | 1991 | 2000 | 29.2 | low | 0 | 0 | 4 | 0 | 0 | 0 |
| moexiprilat | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| pirmagrel | | | | 1983 | 1992 | 37.0 | high | 1 | 11 | 3 | 0 | 0 | 0 |
| loxtidine | | aromatic ether;
piperidines;
primary alcohol;
triazoles | H2-receptor antagonist | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| imazodan | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| rolafagrel | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cilazapril, anhydrous | | dicarboxylic acid monoester;
ethyl ester;
pyridazinodiazepine | antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug | 1992 | 1993 | 31.5 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| fura-2 | | | | 1987 | 1997 | 30.4 | low | 0 | 1 | 4 | 0 | 0 | 0 |
| tepoxalin | | aromatic ether;
hydroxamic acid;
monochlorobenzenes;
pyrazoles | antipyretic;
apoptosis inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
immunomodulator;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1996 | 1998 | 27.0 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| zileuton | | 1-benzothiophenes;
ureas | anti-asthmatic drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
ferroptosis inhibitor;
leukotriene antagonist;
non-steroidal anti-inflammatory drug | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| clopidogrel | | methyl ester;
monochlorobenzenes;
thienopyridine | anticoagulant;
P2Y12 receptor antagonist;
platelet aggregation inhibitor | 1999 | 2018 | 15.5 | low | 0 | 0 | 1 | 1 | 2 | 0 |
| mibefradil | | tetralins | T-type calcium channel blocker | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| tenidap | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| remifentanil | | alpha-amino acid ester;
anilide;
monocarboxylic acid amide;
piperidinecarboxylate ester | intravenous anaesthetic;
mu-opioid receptor agonist;
opioid analgesic;
sedative | 2010 | 2012 | 13.0 | low | 2 | 0 | 0 | 1 | 1 | 0 |
| atorvastatin | | aromatic amide;
dihydroxy monocarboxylic acid;
monofluorobenzenes;
pyrroles;
statin (synthetic) | environmental contaminant;
xenobiotic | 2007 | 2015 | 14.5 | low | 1 | 0 | 0 | 3 | 1 | 0 |
| valsartan | | biphenylyltetrazole;
monocarboxylic acid amide;
monocarboxylic acid | angiotensin receptor antagonist;
antihypertensive agent;
environmental contaminant;
xenobiotic | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| adenosine | | adenosines;
purines D-ribonucleoside | analgesic;
anti-arrhythmia drug;
fundamental metabolite;
human metabolite;
vasodilator agent | 1983 | 2014 | 31.1 | low | 3 | 8 | 10 | 3 | 1 | 0 |
| 3-n-butylphthalide | | benzofurans | | 1997 | 1999 | 26.0 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| vanadates | | trivalent inorganic anion;
vanadium oxoanion | EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor | 1983 | 1998 | 33.0 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| dimethylhydrazines | | | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| scarlet red | | azobenzenes;
bis(azo) compound;
naphthols | carcinogenic agent;
fluorochrome;
histological dye | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| caloreen | | | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| isosorbide-2-mononitrate | | | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| glucose, (beta-d)-isomer | | D-glucopyranose | epitope;
mouse metabolite | 1980 | 2017 | 31.9 | low | 0 | 10 | 11 | 1 | 2 | 0 |
| anisodamine | | | | 1985 | 1992 | 35.6 | low | 0 | 9 | 4 | 0 | 0 | 0 |
| n-methylnicotinamide | | pyridinecarboxamide | metabolite | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 25-hydroxycholesterol | | 25-hydroxy steroid;
oxysterol | human metabolite | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 1,2-distearoyllecithin | | | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose | | gallate ester;
galloyl beta-D-glucose | anti-inflammatory agent;
antineoplastic agent;
geroprotector;
hepatoprotective agent;
plant metabolite;
radiation protective agent;
radical scavenger | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| pyrrolidine dithiocarbamate | | dithiocarbamic acids;
pyrrolidines | anticonvulsant;
antineoplastic agent;
geroprotector;
neuroprotective agent;
NF-kappaB inhibitor;
radical scavenger | 1999 | 2012 | 18.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| glutathione disulfide | | glutathione derivative;
organic disulfide | Escherichia coli metabolite;
mouse metabolite | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| cephalosporin c | | cephalosporin | fungal metabolite | 2004 | 2008 | 18.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| tienoxolol | | | | 1993 | 1993 | 31.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
| tretoquinol | | isoquinolines | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nictindole | | | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| nafagrel | | | | 1990 | 1997 | 30.6 | high | 1 | 0 | 8 | 0 | 0 | 0 |
| web 2086 | | organonitrogen heterocyclic compound;
organosulfur heterocyclic compound | | 1989 | 1998 | 31.7 | low | 0 | 2 | 7 | 0 | 0 | 0 |
| bepafant | | | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| xenon radioisotopes | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1,7-phenanthroline | | phenanthroline | | 1988 | 1993 | 33.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| triazoles | | 1,2,3-triazole | | 1989 | 2014 | 29.4 | low | 0 | 2 | 11 | 0 | 1 | 0 |
| esaprazole | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cloricromen | | coumarins | | 1982 | 1991 | 37.8 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| timegadine | | | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| fenflumizole | | | | 1984 | 1988 | 38.3 | medium | 0 | 3 | 0 | 0 | 0 | 0 |
| 3-methylhistamine | | | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cromakalim | | | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| flosulide | | | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| masoprocol | | nordihydroguaiaretic acid | antineoplastic agent;
hypoglycemic agent;
lipoxygenase inhibitor;
metabolite | 1983 | 1998 | 33.4 | low | 0 | 6 | 7 | 0 | 0 | 0 |
| alacepril | | dipeptide;
thioacetate ester | EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| morniflumate | | (trifluoromethyl)benzenes | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| phorbol-12,13-diacetate | | | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| honokiol | | biphenyls | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| sesamin | | benzodioxoles;
furofuran;
lignan | antineoplastic agent;
neuroprotective agent;
plant metabolite | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| coptisine | | alkaloid | metabolite | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| teleocidin b-4 | | | | 1991 | 1995 | 31.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| tosyllysine chloromethyl ketone | | sulfonic acid derivative | | 1988 | 1997 | 31.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| dauricine | | aromatic ether;
bisbenzylisoquinoline alkaloid;
isoquinolines;
phenols;
tertiary amino compound | plant metabolite | 1987 | 2005 | 30.0 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| 1-benzylimidazole | | | | 1987 | 1989 | 36.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| fc 75 | | alkyltetrahydrofuran;
organofluorine compound | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| noracycline | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ro 22-3581 | | | | 1982 | 1986 | 40.7 | high | 0 | 3 | 0 | 0 | 0 | 0 |
| 3,4-dihydroxyphenylethanol | | catechols;
primary alcohol | antineoplastic agent;
antioxidant;
metabolite | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| ketorolac tromethamine | | organoammonium salt | analgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| clarithromycin | | macrolide antibiotic | antibacterial drug;
environmental contaminant;
protein synthesis inhibitor;
xenobiotic | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| coenzyme a | | adenosine 3',5'-bisphosphate | coenzyme;
Escherichia coli metabolite;
mouse metabolite | 1988 | 1993 | 33.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| nicotine | | 3-(1-methylpyrrolidin-2-yl)pyridine | anxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic | 1982 | 2003 | 34.0 | low | 2 | 9 | 9 | 1 | 0 | 0 |
| fibrinogen | | iditol | fungal metabolite | 1983 | 2020 | 29.5 | low | 3 | 8 | 9 | 0 | 3 | 0 |
| 17-alpha-hydroxypregnenolone | | 17alpha-hydroxy-C21-steroid;
17alpha-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
hydroxypregnenolone;
tertiary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 1980 | 1980 | 44.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| homocysteine | | amino acid zwitterion;
homocysteine;
serine family amino acid | fundamental metabolite;
mouse metabolite | 1986 | 2019 | 22.8 | low | 0 | 1 | 2 | 2 | 1 | 0 |
| acetylsalicylic acid lysinate | | | | 1985 | 1990 | 36.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| 8-((4-chlorophenyl)thio)cyclic-3',5'-amp | | 3',5'-cyclic purine nucleotide;
adenyl ribonucleotide;
aryl sulfide;
organochlorine compound | protein kinase agonist | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| tetrakis-mu-acetylsalicylato-dicopper(ii) | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| zofenopril | | aryl sulfide;
L-proline derivative;
N-acyl-L-amino acid;
thioester | anticonvulsant;
apoptosis inhibitor;
cardioprotective agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
prodrug;
vasodilator agent | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine | | | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| mci 9038 | | peptide | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| firefly luciferin | | 1,3-thiazolemonocarboxylic acid;
benzothiazoles;
imidothioate | luciferin | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cortisol 21-mesylate | | | | 1986 | 1986 | 38.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| cv 6504 | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 3,7-dimethyl-1-propargylxanthine | | | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| foxes | | | | 1992 | 1992 | 32.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| enkephalinamide-met, ala(2)- | | | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| cobalt | | cobalt group element atom;
metal allergen | micronutrient | 1986 | 1990 | 36.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| p-methoxy-n-methylphenethylamine | | aromatic ether;
secondary amino compound | metabolite | 1992 | 1995 | 30.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| fulvestrant | | 17beta-hydroxy steroid;
3-hydroxy steroid;
organofluorine compound;
sulfoxide | antineoplastic agent;
estrogen antagonist;
estrogen receptor antagonist | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1,2-bis(2-aminophenoxy)ethane-n,n,n',n'-tetraacetic acid | | polyamino carboxylic acid;
tetracarboxylic acid | chelator | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| monocrotaline pyrrole | | | | 1988 | 1991 | 34.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| arginyl-glycyl-aspartic acid | | oligopeptide | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 1,4-dihydropyridine | | | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| bosentan anhydrous | | primary alcohol;
pyrimidines;
sulfonamide | antihypertensive agent;
endothelin receptor antagonist | 1997 | 1997 | 27.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| u 74006f | | corticosteroid hormone | | 1993 | 1999 | 28.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| diacetyldichlorofluorescein | | | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole | | ether;
imidazoles;
monomethoxybenzene | TRP channel blocker | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sr 48968 | | | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| fluo-3 | | xanthene dye | fluorochrome | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| fpl 55712 | | aromatic ketone | | 1983 | 1991 | 37.2 | low | 0 | 7 | 2 | 0 | 0 | 0 |
| bradykinin, des-arg(9)- | | oligopeptide | bradykinin receptor B2 agonist | 1991 | 1993 | 32.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| indobufen | | isoindoles | | 1986 | 1996 | 33.0 | low | 1 | 1 | 1 | 0 | 0 | 0 |
| 3-((3-cholamidopropyl)dimethylammonium)-1-propanesulfonate | | 1,1-diunsubstituted alkanesulfonate | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cv 3988 | | | | 1995 | 2002 | 25.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| sivelestat | | N-acylglycine;
pivalate ester | | 1994 | 2004 | 25.7 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| 22-hydroxycholesterol | | cholanoid | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| propionylcarnitine | | O-acylcarnitine | analgesic;
antirheumatic drug;
cardiotonic drug;
human metabolite;
peripheral nervous system drug | 1990 | 1994 | 32.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| cv 6209 | | | | 1989 | 1991 | 34.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| methoctramine | | hydrochloride | muscarinic antagonist | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| perindopril | | alpha-amino acid ester;
dicarboxylic acid monoester;
ethyl ester;
organic heterobicyclic compound | antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor | 1992 | 1994 | 31.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| fr 139317 | | | | 1995 | 1998 | 27.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| procyanidin | | proanthocyanidin | | 2001 | 2013 | 19.0 | low | 1 | 0 | 0 | 3 | 1 | 0 |
| sri 63-441 | | | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| tesmilifene | | diarylmethane | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1-hexadecyl-2-acetyl-glycero-3-phosphocholine | | 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine | antihypertensive agent;
beta-adrenergic antagonist;
bronchoconstrictor agent;
hematologic agent;
vasodilator agent | 1983 | 2002 | 33.0 | low | 0 | 30 | 51 | 1 | 0 | 0 |
| exp3174 | | biphenylyltetrazole;
imidazoles;
organochlorine compound | metabolite | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| deoxyglucose | | | | 1985 | 1994 | 34.2 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| thromboxanes | | | | 1979 | 2017 | 37.9 | medium | 22 | 271 | 41 | 10 | 4 | 0 |
| gastrodin | | glycoside | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 2,5-bis(3,4,5-trimethoxyphenyl)tetrahydrofuran | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sc 58125 | | organofluorine compound;
pyrazoles;
sulfone | antineoplastic agent;
cyclooxygenase 2 inhibitor | 1996 | 2014 | 21.0 | low | 0 | 0 | 2 | 0 | 1 | 0 |
| hwa 138 | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| bw 373u86 | | diarylmethane | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| nitroaspirin | | carbonyl compound | | 2000 | 2001 | 23.7 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| lithospermate b | | | | 1993 | 1994 | 30.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| astilbin | | 3'-hydroxyflavanones;
4'-hydroxyflavanones;
alpha-L-rhamnoside;
flavanone glycoside;
monosaccharide derivative;
tetrahydroxyflavanone | anti-inflammatory agent;
plant metabolite;
radical scavenger | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 2-aminomethyl-4-t-butyl-6-iodophenol | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ar 12463 | | | | 1987 | 1988 | 36.5 | medium | 0 | 2 | 0 | 0 | 0 | 0 |
| n-(9h-(2,7-dimethylfluoren-9-ylmethoxy)carbonyl)leucine | | | | 1993 | 1997 | 28.7 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| mozavaptan | | benzamides | aquaretic | 1995 | 1995 | 29.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| caprylates | | fatty acid anion 8:0;
straight-chain saturated fatty acid anion | human metabolite;
Saccharomyces cerevisiae metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ah 6809 | | xanthones | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid | | | | 1988 | 1993 | 34.2 | medium | 0 | 3 | 2 | 0 | 0 | 0 |
| valdecoxib | | isoxazoles;
sulfonamide | antipyretic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 2006 | 2006 | 18.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| parecoxib | | isoxazoles;
N-sulfonylcarboxamide | cyclooxygenase 2 inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug | 2006 | 2006 | 18.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| (20s)-20-hydroxycholesterol | | 20-hydroxy steroid;
3beta-hydroxy-Delta(5)-steroid;
oxysterol | human metabolite;
mouse metabolite | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| l 658758 | | | | 2004 | 2008 | 18.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| sinitrodil | | | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ly 255283 | | aromatic ketone | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| dx 9065a | | | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| l 651392 | | | | 1989 | 1993 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| fpl 57231 | | | | 1986 | 1988 | 37.2 | medium | 0 | 5 | 0 | 0 | 0 | 0 |
| procyanidin b2 | | biflavonoid;
hydroxyflavan;
polyphenol;
proanthocyanidin | antioxidant;
metabolite | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| dehydroacetic acid | | ketone;
pyran-2,4-dione | antibacterial agent;
fungicide;
plasticiser | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| peroxynitrous acid | | nitrogen oxoacid | | 2001 | 2017 | 17.3 | low | 0 | 0 | 0 | 4 | 2 | 0 |
| mk 0663 | | bipyridines;
organochlorine compound;
sulfone | cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug | 2007 | 2007 | 17.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| glycyl-prolyl-arginyl-proline | | | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| bay x 1005 | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cgp 42112a | | benzyl ester;
oligopeptide;
pyridinecarboxamide | angiotensin receptor agonist;
anti-inflammatory agent;
antineoplastic agent;
neuroprotective agent;
vasodilator agent | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| angiotensin ii, des-phe(8)- | | amino acid zwitterion;
angiotensin | vasodilator agent | 1995 | 2015 | 20.0 | low | 0 | 0 | 1 | 1 | 1 | 0 |
| 2-chloro-n(6)cyclopentyladenosine | | | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 3-tyr-octreotide | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ramatroban | | organic molecular entity | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| bq 610 | | | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| lipid x | | N-acyl-D-glucosamine 1-phosphate | Escherichia coli metabolite | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| pd 145065 | | | | 1993 | 1998 | 28.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| glycerophosphoinositol 4,5-bisphosphate | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| methotrexate | | dicarboxylic acid;
monocarboxylic acid amide;
pteridines | abortifacient;
antimetabolite;
antineoplastic agent;
antirheumatic drug;
dermatologic drug;
DNA synthesis inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
immunosuppressive agent | 1987 | 1991 | 34.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| ph cl 28a | | | | 1990 | 1993 | 32.5 | high | 0 | 0 | 2 | 0 | 0 | 0 |
| l 640035 | | | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| ar 12456 | | | | 1988 | 1988 | 36.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| 6-(5-methylimidazol-1-yl)methyl-2-naphthoic acid hydrochloride | | | | 1992 | 1992 | 32.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
| ro 22-9194 | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sipi 549 | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| l 670596 | | carbazoles | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| l 636499 | | | | 1988 | 1988 | 36.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| e 5880 | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| mdl 73404 | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cgs 22652 | | | | 1993 | 1993 | 31.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
| ici d8731 | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| l 703606 | | | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| omega-n-methylarginine | | amino acid zwitterion;
arginine derivative;
guanidines;
L-arginine derivative;
non-proteinogenic L-alpha-amino acid | | 1992 | 2009 | 27.6 | low | 3 | 0 | 21 | 3 | 0 | 0 |
| proline | | amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid | algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 1981 | 1997 | 36.6 | low | 0 | 4 | 3 | 0 | 0 | 0 |
| kc 764 | | | | 1992 | 1994 | 31.0 | high | 1 | 0 | 2 | 0 | 0 | 0 |
| ezetimibe | | azetidines;
beta-lactam;
organofluorine compound | anticholesteremic drug;
antilipemic drug;
antimetabolite | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 4-((3-pyridinylmethyl)amino)benzoic acid | | | | 1983 | 1983 | 41.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| is 741 | | | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| phorbols | | diterpene;
terpenoid fundamental parent | | 1980 | 1986 | 40.0 | low | 0 | 5 | 0 | 0 | 0 | 0 |
| 2,3-dinor-6,15-diketo-13,14-dihydroprostaglandin f1alpha | | | | 1980 | 1982 | 43.0 | high | 0 | 3 | 0 | 0 | 0 | 0 |
| chinoin 127 | | | | 1992 | 1992 | 32.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
| naproxen | | methoxynaphthalene;
monocarboxylic acid | antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
environmental contaminant;
gout suppressant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic | 1984 | 2010 | 30.4 | low | 9 | 9 | 4 | 6 | 0 | 0 |
| hydroxyl radical | | oxygen hydride;
oxygen radical;
reactive oxygen species | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| atrasentan | | pyrrolidines | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| prostaglandins b | | | | 1981 | 1993 | 37.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| methyl 2-((3,4-dihydro-3,4-dioxo-1-naphthalenyl)amino)benzoate | | | | 1993 | 1993 | 31.0 | medium | 0 | 0 | 2 | 0 | 0 | 0 |
| fk 3311 | | | | 2001 | 2001 | 23.0 | medium | 0 | 0 | 0 | 3 | 0 | 0 |
| technetium tc 99m pentetate | | | | 1987 | 1998 | 33.0 | low | 1 | 2 | 1 | 0 | 0 | 0 |
| trilobine | | isoquinolines | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| aminopterin | | dicarboxylic acid | EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
mutagen | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| biotin | | biotins;
vitamin B7 | coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| angiotensin ii | | amino acid zwitterion;
angiotensin II | human metabolite | 1981 | 2017 | 31.7 | low | 4 | 49 | 47 | 11 | 6 | 0 |
| 6,15-diketo-13,14-dihydroprostaglandin f1alpha | | | | 1981 | 1999 | 40.0 | high | 0 | 10 | 1 | 0 | 0 | 0 |
| atropine | | | | 1984 | 1992 | 34.6 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| 4-aminobenzoic acid-n-mannoside | | | | 1988 | 1988 | 36.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| 7-hydroxy-5,11-dioxotetranorprostane-1,16-dioic acid | | prostanoid | | 1994 | 2005 | 24.5 | low | 1 | 0 | 1 | 1 | 0 | 0 |
| ropivacaine | | piperidinecarboxamide;
ropivacaine | local anaesthetic | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| lu 135252 | | | | 1998 | 2002 | 24.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| scutellarin | | glucosiduronic acid;
glycosyloxyflavone;
monosaccharide derivative;
trihydroxyflavone | antineoplastic agent;
proteasome inhibitor | 1989 | 1993 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| esculentin steroid | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| uk 34787 | | | | 1986 | 1986 | 38.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| cholic acid | | 12alpha-hydroxy steroid;
3alpha-hydroxy steroid;
7alpha-hydroxy steroid;
bile acid;
C24-steroid;
trihydroxy-5beta-cholanic acid | human metabolite;
mouse metabolite | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| cortisone | | 11-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone | human metabolite;
mouse metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 3-nitrotyrosine | | 2-nitrophenols;
C-nitro compound;
nitrotyrosine;
non-proteinogenic alpha-amino acid | | 2011 | 2017 | 10.0 | low | 0 | 0 | 0 | 0 | 2 | 0 |
| 2-hydroxyestradiol | | 17beta-hydroxy steroid;
2-hydroxy steroid | carcinogenic agent;
human metabolite;
metabolite;
mouse metabolite;
prodrug | 1981 | 1984 | 41.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| benzofurans | | | | 1986 | 2009 | 32.6 | low | 0 | 9 | 6 | 1 | 0 | 0 |
| sodium bromide | | bromide salt;
inorganic sodium salt | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| acetylstrophanthidin | | acetate ester | anti-arrhythmia drug | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| sorbinil | | azaspiro compound;
chromanes;
imidazolidinone;
organofluorine compound;
oxaspiro compound | antioxidant;
EC 1.1.1.21 (aldehyde reductase) inhibitor | 1989 | 1991 | 34.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| dihydropyridines | | | | 1990 | 2002 | 28.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| lithium chloride | | inorganic chloride;
lithium salt | antimanic drug;
geroprotector | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| glycogen | | | | 1994 | 1997 | 28.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| fibrin | | peptide | | 1982 | 1999 | 34.9 | low | 0 | 7 | 5 | 0 | 0 | 0 |
| bradykinin | | oligopeptide | human blood serum metabolite;
vasodilator agent | 1981 | 2008 | 31.6 | low | 3 | 45 | 47 | 11 | 0 | 0 |
| glucosamine | | D-glucosamine | Escherichia coli metabolite;
geroprotector;
mouse metabolite | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| elastin | | oligopeptide | | 2012 | 2012 | 12.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| raffinose | | raffinose family oligosaccharide;
trisaccharide | mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| oxytocin | | heterodetic cyclic peptide;
peptide hormone | oxytocic;
vasodilator agent | 1980 | 2001 | 31.9 | low | 0 | 5 | 6 | 2 | 0 | 0 |
| 3,4-dihydroxyphenyllactic acid | | 2-hydroxy monocarboxylic acid;
catechols | | 1986 | 2014 | 20.7 | low | 0 | 1 | 0 | 1 | 1 | 0 |
| inositol 1,4,5-trisphosphate | | myo-inositol trisphosphate | mouse metabolite | 1987 | 1996 | 33.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| ouabain | | 11alpha-hydroxy steroid;
14beta-hydroxy steroid;
5beta-hydroxy steroid;
alpha-L-rhamnoside;
cardenolide glycoside;
steroid hormone | anti-arrhythmia drug;
cardiotonic drug;
EC 2.3.3.1 [citrate (Si)-synthase] inhibitor;
EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor;
EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor;
EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor;
ion transport inhibitor;
plant metabolite | 1983 | 2000 | 34.4 | low | 0 | 3 | 2 | 0 | 0 | 0 |
| puromycin | | puromycins | antiinfective agent;
antimicrobial agent;
antineoplastic agent;
EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor;
EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor;
nucleoside antibiotic;
protein synthesis inhibitor | 1982 | 1996 | 35.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| tosylphenylalanyl chloromethyl ketone | | alpha-chloroketone;
sulfonamide | alkylating agent;
serine proteinase inhibitor | 1988 | 1997 | 31.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| monoiodotyrosine | | amino acid zwitterion;
L-tyrosine derivative;
monoiodotyrosine;
non-proteinogenic L-alpha-amino acid | EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor;
human metabolite;
mouse metabolite | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| nitroarginine | | guanidines;
L-arginine derivative;
N-nitro compound;
non-proteinogenic L-alpha-amino acid | | 1991 | 2004 | 27.6 | low | 0 | 0 | 22 | 5 | 0 | 0 |
| adenosine 5'-o-(3-thiotriphosphate) | | nucleoside triphosphate analogue | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 2-hydroxyestrone | | 2-hydroxy steroid;
catechols | human metabolite | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| pentazocine | | benzazocine | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| pancuronium | | acetate ester;
steroid ester | cholinergic antagonist;
muscle relaxant;
nicotinic antagonist | 1986 | 1986 | 38.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| ryanodine | | | | 1985 | 1997 | 32.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| ginsenoside rg1 | | 12beta-hydroxy steroid;
3beta-hydroxy-4,4-dimethylsteroid;
beta-D-glucoside;
ginsenoside;
tetracyclic triterpenoid | neuroprotective agent;
pro-angiogenic agent | 1998 | 1998 | 26.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| lignans | | | | 2000 | 2005 | 21.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| bq 123 | | cyclic peptide | | 1993 | 2004 | 26.5 | low | 0 | 0 | 6 | 2 | 0 | 0 |
| n-formylmethionine leucyl-phenylalanine | | tripeptide | | 1983 | 1999 | 33.2 | low | 0 | 8 | 8 | 0 | 0 | 0 |
| sodium arsenite | | arsenic molecular entity;
inorganic sodium salt | antibacterial agent;
antifungal agent;
antineoplastic agent;
carcinogenic agent;
herbicide;
insecticide;
rodenticide | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ergonovine | | ergot alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound;
primary alcohol;
secondary amino compound;
tertiary amino compound | diagnostic agent;
fungal metabolite;
oxytocic;
toxin | 1985 | 1989 | 37.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| betadex | | cyclodextrin | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| tretinoin | | retinoic acid;
vitamin A | anti-inflammatory agent;
antineoplastic agent;
antioxidant;
AP-1 antagonist;
human metabolite;
keratolytic drug;
retinoic acid receptor agonist;
retinoid X receptor agonist;
signalling molecule | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| arachidonic acid | | icosa-5,8,11,14-tetraenoic acid;
long-chain fatty acid;
omega-6 fatty acid | Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
human metabolite;
mouse metabolite | 1981 | 2021 | 34.2 | low | 11 | 308 | 161 | 33 | 7 | 2 |
| prostaglandin h2 | | olefinic compound;
oxylipin;
prostaglandins H;
secondary alcohol | mouse metabolite | 1982 | 2004 | 34.0 | low | 0 | 15 | 11 | 2 | 0 | 0 |
| phosphoramidon | | deoxyaldohexose phosphate;
dipeptide | bacterial metabolite;
EC 3.4.24.11 (neprilysin) inhibitor;
EC 3.4.24.71 (endothelin-converting enzyme 1) inhibitor | 1998 | 2004 | 23.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| resveratrol | | resveratrol | antioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger | 2005 | 2009 | 17.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| retinol | | retinol;
vitamin A | human metabolite;
mouse metabolite;
plant metabolite | 1992 | 1996 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| oleic acid | | octadec-9-enoic acid | antioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent | 1982 | 2004 | 30.0 | low | 1 | 2 | 7 | 2 | 0 | 0 |
| tacrolimus | | macrolide lactam | bacterial metabolite;
immunosuppressive agent | 1993 | 2014 | 23.4 | low | 3 | 0 | 3 | 1 | 1 | 0 |
| ferulic acid | | ferulic acids | anti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
MALDI matrix material;
plant metabolite | 1988 | 1990 | 35.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| cocaine | | benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid | adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic | 1994 | 1996 | 29.3 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| cocaine | | benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid | adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic | 1994 | 2001 | 27.8 | low | 1 | 0 | 3 | 1 | 0 | 0 |
| eicosapentaenoic acid | | icosapentaenoic acid;
omega-3 fatty acid | anticholesteremic drug;
antidepressant;
antineoplastic agent;
Daphnia galeata metabolite;
fungal metabolite;
micronutrient;
mouse metabolite;
nutraceutical | 1981 | 2007 | 33.5 | low | 2 | 13 | 11 | 4 | 0 | 0 |
| thapsigargin | | butyrate ester;
organic heterotricyclic compound;
sesquiterpene lactone | calcium channel blocker;
EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor | 1996 | 2003 | 24.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| mycophenolic acid | | 2-benzofurans;
gamma-lactone;
monocarboxylic acid;
phenols | anticoronaviral agent;
antimicrobial agent;
antineoplastic agent;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
environmental contaminant;
immunosuppressive agent;
mycotoxin;
Penicillium metabolite;
xenobiotic | 2001 | 2018 | 16.0 | low | 1 | 0 | 0 | 2 | 1 | 0 |
| tetragastrin | | peptidyl amide;
tetrapeptide | anxiogenic;
human metabolite | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| zithromax | | macrolide antibiotic | antibacterial drug;
environmental contaminant;
xenobiotic | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| adenosine-5'-(n-ethylcarboxamide) | | adenosines;
monocarboxylic acid amide | adenosine A1 receptor agonist;
adenosine A2A receptor agonist;
antineoplastic agent;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| prostaglandin d2 | | prostaglandins D | human metabolite;
mouse metabolite | 1982 | 2013 | 32.2 | low | 2 | 46 | 29 | 12 | 4 | 0 |
| h 89 | | N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| imidazolidines | | azacycloalkane;
imidazolidines;
saturated organic heteromonocyclic parent | | 1989 | 1991 | 34.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| kt 5720 | | carboxylic ester;
gamma-lactam;
hemiaminal;
indolocarbazole;
organic heterooctacyclic compound;
semisynthetic derivative;
tertiary alcohol | EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor | 2005 | 2007 | 18.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| dactinomycin | | actinomycin | mutagen | 1980 | 1997 | 35.3 | low | 0 | 10 | 4 | 0 | 0 | 0 |
| gamma-sitosterol | | 3beta-hydroxy-Delta(5)-steroid;
3beta-sterol;
phytosterols | marine metabolite;
plant metabolite | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| melphalan | | L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound | alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| enkephalin, leucine | | pentapeptide;
peptide zwitterion | analgesic;
delta-opioid receptor agonist;
human metabolite;
mu-opioid receptor agonist;
neurotransmitter;
rat metabolite | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1-deaza-2-chloro-n(6)-cyclopentyladenosine | | | | 1992 | 1992 | 32.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
| sodium bicarbonate | | one-carbon compound;
organic sodium salt | antacid;
food anticaking agent | 1989 | 1993 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| sodium acetate, anhydrous | | organic sodium salt | NMR chemical shift reference compound | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| dipyrone | | organic sodium salt | anti-inflammatory agent;
antipyretic;
antirheumatic drug;
cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug;
prodrug | 1985 | 1986 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| cholestane-3,5,6-triol | | | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| tolfenamic acid | | aminobenzoic acid;
organochlorine compound;
secondary amino compound | EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
EC 2.7.1.33 (pantothenate kinase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug | 1983 | 1985 | 40.0 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| carbenoxolone sodium | | triterpenoid | | 1985 | 1992 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| elaidic acid | | octadec-9-enoic acid | food component | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| glycosides | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| stilbenes | | stilbene | | 1995 | 2009 | 21.0 | low | 0 | 0 | 1 | 2 | 0 | 0 |
| phenyl-n-tert-butylnitrone | | | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| buprenorphine | | morphinane alkaloid | delta-opioid receptor antagonist;
kappa-opioid receptor antagonist;
mu-opioid receptor agonist;
opioid analgesic | 2000 | 2000 | 24.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| lypressin | | cyclic peptide | | 1985 | 1989 | 36.0 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| arginine vasopressin | | vasopressin | cardiovascular drug;
hematologic agent;
mitogen | 1983 | 2009 | 33.7 | low | 2 | 14 | 6 | 3 | 0 | 0 |
| sesquiterpenes | | | | 1985 | 1986 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| sb 366791 | | | | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| ag-213 | | | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 5-(4-chlorophenyl)-2-furanpropionic acid | | | | 1993 | 1993 | 31.0 | medium | 0 | 0 | 1 | 0 | 0 | 0 |
| cotinine | | N-alkylpyrrolidine;
pyridines;
pyrrolidin-2-ones;
pyrrolidine alkaloid | antidepressant;
biomarker;
human xenobiotic metabolite;
plant metabolite | 1988 | 2020 | 21.7 | low | 1 | 1 | 1 | 0 | 1 | 0 |
| curcumin | | aromatic ether;
beta-diketone;
diarylheptanoid;
enone;
polyphenol | anti-inflammatory agent;
antifungal agent;
antineoplastic agent;
biological pigment;
contraceptive drug;
dye;
EC 1.1.1.205 (IMP dehydrogenase) inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor;
EC 1.8.1.9 (thioredoxin reductase) inhibitor;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
flavouring agent;
food colouring;
geroprotector;
hepatoprotective agent;
immunomodulator;
iron chelator;
ligand;
lipoxygenase inhibitor;
metabolite;
neuroprotective agent;
nutraceutical;
radical scavenger | 1997 | 2009 | 21.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| methimazole | | 1,3-dihydroimidazole-2-thiones | antithyroid drug | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| sulindac | | monocarboxylic acid;
organofluorine compound;
sulfoxide | analgesic;
antineoplastic agent;
antipyretic;
apoptosis inducer;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
prodrug;
tocolytic agent | 1983 | 1999 | 37.1 | low | 8 | 22 | 3 | 0 | 0 | 0 |
| capsaicin | | capsaicinoid | non-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker | 1990 | 2009 | 22.5 | low | 0 | 0 | 5 | 10 | 0 | 0 |
| enclomiphene | | | | 1985 | 1987 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| metiamide | | imidazoles | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| tosylarginine methyl ester | | guanidines;
L-arginine ester;
methyl ester;
sulfonamide | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| chlorogenic acid | | cinnamate ester;
tannin | food component;
plant metabolite | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| thiobarbituric acid | | barbiturates | allergen;
reagent | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 1,3-dimethylthiourea | | | | 1985 | 1988 | 37.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| thiourea | | one-carbon compound;
thioureas;
ureas | antioxidant;
chromophore | 1985 | 1988 | 37.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| D-fructopyranose | | cyclic hemiketal;
D-fructose;
fructopyranose | sweetening agent | 1989 | 2016 | 21.9 | low | 0 | 1 | 2 | 3 | 1 | 0 |
| thioacetamide | | thiocarboxamide | hepatotoxic agent | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| tempo | | aminoxyls;
piperidines | catalyst;
ferroptosis inhibitor;
radical scavenger | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| capsazepine | | benzazepine;
catechols;
monochlorobenzenes;
thioureas | capsaicin receptor antagonist | 1994 | 2009 | 20.2 | low | 0 | 0 | 1 | 5 | 0 | 0 |
| 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole | | benzoic acid;
imidazolines;
organic radical | apoptosis inhibitor;
radical scavenger | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| tamoxifen | | stilbenoid;
tertiary amino compound | angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator | 1985 | 1995 | 33.0 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| sodium taurodeoxycholate | | bile acid taurine conjugate | human metabolite | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nadp | | | | 1978 | 1981 | 44.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| 1,1-diphenyl-2-picrylhydrazyl | | | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| tetrachlorodecaoxide | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| rhyncophylline | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| thiopental | | barbiturates | anticonvulsant;
drug allergen;
environmental contaminant;
intravenous anaesthetic;
sedative;
xenobiotic | 1982 | 1986 | 40.0 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| ranitidine | | C-nitro compound;
furans;
organic sulfide;
tertiary amino compound | anti-ulcer drug;
drug allergen;
environmental contaminant;
H2-receptor antagonist;
xenobiotic | 1986 | 2007 | 29.3 | low | 1 | 1 | 1 | 1 | 0 | 0 |
| 4,5-dihydro-6-(4-(imidazol-1-yl)phenyl)-5-methyl-3(2h)-pyridazinone | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| lithium | | alkali metal atom | | 1991 | 1998 | 29.5 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| nitrogen dioxide | | nitrogen oxide | | 1986 | 2001 | 29.0 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| dermatan sulfate | | amino disaccharide;
glycosylgalactose derivative;
iduronic acids;
oligosaccharide sulfate | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| nizatidine | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 1,2-bis(2-aminophenoxy)ethane n,n,n',n'-tetraacetic acid acetoxymethyl ester | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| indium oxine | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| dimethyl(2-hydroxy-5-nitrobenzyl)sulfonium | | | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| gea 3162 | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| lysine clonixinate | | organoammonium salt | antipyretic;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
lipoxygenase inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
platelet aggregation inhibitor;
vasodilator agent | 1995 | 1998 | 27.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| cytellin | | | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| ginsenosides | | | | 1986 | 1998 | 30.8 | low | 1 | 1 | 5 | 0 | 0 | 0 |
| 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine | | adenosines;
dicarboxylic acid monoamide;
monocarboxylic acid | adenosine A2A receptor agonist;
anti-inflammatory agent | 1992 | 1994 | 31.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| ovalbumin | | | | 1983 | 2018 | 29.8 | low | 0 | 4 | 5 | 1 | 1 | 0 |
| 4-aminopyrrolidine-2,4-dicarboxylic acid | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sodium dodecyl sulfate | | organic sodium salt | detergent;
protein denaturant | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| l 663536 | | aryl sulfide;
indoles;
monocarboxylic acid;
monochlorobenzenes | antineoplastic agent;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
leukotriene antagonist | 2002 | 2004 | 21.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| naphthoquinones | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| sc 560 | | aromatic ether;
monochlorobenzenes;
organofluorine compound;
pyrazoles | angiogenesis modulating agent;
antineoplastic agent;
apoptosis inducer;
cyclooxygenase 1 inhibitor;
non-steroidal anti-inflammatory drug | 2001 | 2014 | 18.3 | low | 0 | 0 | 0 | 8 | 2 | 0 |
| diethyl maleate | | ethyl ester;
maleate ester | glutathione depleting agent | 1984 | 1993 | 33.6 | low | 0 | 1 | 4 | 0 | 0 | 0 |
| quercetin | | 7-hydroxyflavonol;
pentahydroxyflavone | antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger | 1990 | 2013 | 23.6 | low | 0 | 0 | 3 | 1 | 1 | 0 |
| bilirubin | | biladienes;
dicarboxylic acid | antioxidant;
human metabolite;
mouse metabolite | 1990 | 2005 | 26.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| dinoprostone | | prostaglandins E | human metabolite;
mouse metabolite;
oxytocic | 1979 | 2021 | 33.3 | low | 41 | 612 | 466 | 105 | 10 | 1 |
| dinoprost | | monocarboxylic acid;
prostaglandins Falpha | human metabolite;
mouse metabolite | 1979 | 2016 | 34.4 | low | 18 | 313 | 148 | 40 | 7 | 0 |
| leukotriene a4 | | epoxy fatty acid;
leukotriene;
long-chain fatty acid;
oxylipin;
polyunsaturated fatty acid | human metabolite;
mouse metabolite;
plant metabolite | 1990 | 2002 | 30.2 | low | 0 | 0 | 3 | 1 | 0 | 0 |
| arachidonyltrifluoromethane | | fatty acid derivative;
ketone;
olefinic compound;
organofluorine compound | EC 3.1.1.4 (phospholipase A2) inhibitor | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| linoleic acid | | octadecadienoic acid;
omega-6 fatty acid | algal metabolite;
Daphnia galeata metabolite;
plant metabolite | 1982 | 2008 | 31.2 | low | 3 | 8 | 8 | 5 | 0 | 0 |
| calcitriol | | D3 vitamins;
hydroxycalciol;
triol | antineoplastic agent;
antipsoriatic;
bone density conservation agent;
calcium channel agonist;
calcium channel modulator;
hormone;
human metabolite;
immunomodulator;
metabolite;
mouse metabolite;
nutraceutical | 1985 | 1992 | 34.2 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| beta carotene | | carotenoid beta-end derivative;
cyclic carotene | antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A | 2007 | 2007 | 17.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| leukotriene b4 | | dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid | human metabolite;
mouse metabolite;
plant metabolite;
vasoconstrictor agent | 1981 | 2016 | 31.1 | low | 6 | 36 | 84 | 10 | 2 | 0 |
| leukotriene c4 | | leukotriene | bronchoconstrictor agent;
human metabolite;
mouse metabolite | 1994 | 2006 | 26.2 | low | 4 | 0 | 24 | 5 | 0 | 0 |
| thromboxane a2 | | epoxy monocarboxylic acid;
thromboxanes A | mouse metabolite | 1980 | 2017 | 32.9 | medium | 45 | 243 | 196 | 43 | 10 | 0 |
| 8,11,14-eicosatrienoic acid | | fatty acid 20:3;
long-chain fatty acid | fungal metabolite;
human metabolite;
nutraceutical | 1985 | 2005 | 29.8 | low | 0 | 4 | 6 | 2 | 0 | 0 |
| rumenic acid | | octadeca-9,11-dienoic acid | | 2007 | 2015 | 13.0 | low | 0 | 0 | 0 | 1 | 1 | 0 |
| 15-keto-13,14-dihydroprostaglandin e2 | | prostaglandins E | | 1980 | 1997 | 38.9 | medium | 1 | 12 | 1 | 0 | 0 | 0 |
| 15-ketoprostaglandin e2 | | prostaglandins E | | 1981 | 1982 | 42.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| alprostadil | | prostaglandins E | anticoagulant;
human metabolite;
platelet aggregation inhibitor;
vasodilator agent | 1979 | 2017 | 34.1 | low | 5 | 33 | 16 | 6 | 1 | 0 |
| 5-hydroxy-6,8,11,14-eicosatetraenoic acid | | HETE | human metabolite;
mouse metabolite | 1985 | 1998 | 33.8 | low | 0 | 8 | 6 | 0 | 0 | 0 |
| cholecalciferol | | D3 vitamins;
hydroxy seco-steroid;
seco-cholestane;
secondary alcohol;
steroid hormone | geroprotector;
human metabolite | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| rutin | | disaccharide derivative;
quercetin O-glucoside;
rutinoside;
tetrahydroxyflavone | antioxidant;
metabolite | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| leukotriene d4 | | dipeptide;
leukotriene;
organic sulfide | bronchoconstrictor agent;
human metabolite;
mouse metabolite | 1994 | 2009 | 22.6 | low | 0 | 0 | 5 | 3 | 0 | 0 |
| leukotriene e4 | | amino dicarboxylic acid;
L-cysteine thioether;
leukotriene;
non-proteinogenic L-alpha-amino acid;
secondary alcohol | | 1983 | 2002 | 31.0 | low | 2 | 4 | 11 | 2 | 0 | 0 |
| prostaglandin a2 | | prostaglandins A | human metabolite | 1983 | 1998 | 36.0 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| prostaglandin b2 | | prostaglandins B | human metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| prostaglandin g2 | | prostaglandins G | human metabolite;
mouse metabolite | 1987 | 2002 | 28.7 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| 9-deoxy-delta-9-prostaglandin d2 | | prostaglandins J | human metabolite | 2004 | 2011 | 17.3 | low | 0 | 0 | 0 | 2 | 1 | 0 |
| 15-ketoprostaglandin f2alpha | | prostaglandins Falpha | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 6-ketoprostaglandin e1 | | prostaglandins E | metabolite;
platelet aggregation inhibitor | 1981 | 2017 | 37.0 | medium | 0 | 14 | 1 | 0 | 1 | 0 |
| 11-dehydro-thromboxane b2 | | thromboxane | human metabolite | 1986 | 2018 | 24.7 | medium | 19 | 4 | 40 | 15 | 7 | 0 |
| arachidonic acid omega-9 hydroperoxide | | HPETE | mouse metabolite | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| lipoxin a4 | | hydroxy polyunsaturated fatty acid;
lipoxin;
long-chain fatty acid | human metabolite;
metabolite | 1989 | 2014 | 22.5 | low | 0 | 1 | 0 | 0 | 1 | 0 |
| gamma-linolenic acid | | linolenic acid;
omega-6 fatty acid | human metabolite;
mouse metabolite;
plant metabolite | 1985 | 2000 | 32.9 | low | 3 | 5 | 4 | 0 | 0 | 0 |
| alpha-linolenic acid | | linolenic acid;
omega-3 fatty acid | micronutrient;
mouse metabolite;
nutraceutical | 1984 | 2007 | 30.0 | low | 0 | 2 | 6 | 1 | 0 | 0 |
| leukotriene f-4 | | dipeptide;
leukotriene;
organic sulfide | human metabolite | 1985 | 1991 | 36.0 | medium | 0 | 1 | 1 | 0 | 0 | 0 |
| prostaglandin f1 | | prostaglandins Falpha | human metabolite | 1981 | 2004 | 35.5 | low | 1 | 8 | 2 | 2 | 0 | 0 |
| prostaglandin f3alpha | | prostaglandins Falpha | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| genistein | | 7-hydroxyisoflavones | antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
geroprotector;
human urinary metabolite;
phytoestrogen;
plant metabolite;
tyrosine kinase inhibitor | 1997 | 2010 | 20.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| amphotericin b | | antibiotic antifungal drug;
macrolide antibiotic;
polyene antibiotic | antiamoebic agent;
antiprotozoal drug;
bacterial metabolite | 1991 | 1992 | 32.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| carboprost | | hydroxy monocarboxylic acid | abortifacient;
oxytocic | 1980 | 1981 | 43.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| astaxanthine | | carotenol;
carotenone | animal metabolite;
anticoagulant;
antioxidant;
food colouring;
plant metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| okanin | | benzenetriol;
chalcones | plant metabolite | 2022 | 2022 | 2.0 | low | 0 | 0 | 0 | 0 | 0 | 1 |
| esculetin | | hydroxycoumarin | antioxidant;
plant metabolite;
ultraviolet filter | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| zearalenone | | macrolide;
resorcinols | fungal metabolite;
mycoestrogen | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| baicalein | | trihydroxyflavone | angiogenesis inhibitor;
anti-inflammatory agent;
antibacterial agent;
anticoronaviral agent;
antifungal agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor;
EC 4.1.1.17 (ornithine decarboxylase) inhibitor;
ferroptosis inhibitor;
geroprotector;
hormone antagonist;
plant metabolite;
prostaglandin antagonist;
radical scavenger | 2000 | 2004 | 22.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| rosmarinic acid | | rosmarinic acid | geroprotector;
plant metabolite | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| rottlerin | | aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone | anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| prostaglandin a1 | | prostaglandins A | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| anandamide | | endocannabinoid;
N-acylethanolamine 20:4 | human blood serum metabolite;
neurotransmitter;
vasodilator agent | 2006 | 2007 | 17.3 | low | 0 | 0 | 0 | 3 | 0 | 0 |
| astragalin | | beta-D-glucoside;
kaempferol O-glucoside;
monosaccharide derivative;
trihydroxyflavone | plant metabolite;
trypanocidal drug | 2020 | 2020 | 4.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| lafutidine | | organic molecular entity | | 2006 | 2007 | 17.5 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| plaunotol | | diterpenoid;
primary alcohol | anti-ulcer drug;
antibacterial agent;
antineoplastic agent;
apoptosis inducer;
nephroprotective agent;
plant metabolite;
vulnerary | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 8-epi-prostaglandin f2alpha | | F2-isoprostane | biomarker;
bronchoconstrictor agent;
vasoconstrictor agent | 1994 | 2015 | 20.1 | low | 4 | 0 | 6 | 7 | 5 | 0 |
| 4-hydroxyestradiol | | 4-hydroxy steroid | metabolite | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| misoprostol | | | | 1986 | 1996 | 33.0 | low | 2 | 1 | 2 | 0 | 0 | 0 |
| ozagrel | | cinnamic acids | | 1983 | 2010 | 32.5 | medium | 2 | 30 | 33 | 6 | 0 | 0 |
| ethamolin | | long-chain fatty acid | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| trans-10,cis-12-conjugated linoleic acid | | octadeca-10,12-dienoic acid | | 2015 | 2015 | 9.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| 13-hydroxy-9,11-octadecadienoic acid | | octadecadienoic acid | | 1987 | 1993 | 33.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| 15-keto-13,14-dihydroprostaglandin f2alpha | | ketone;
prostaglandins Falpha | metabolite | 1979 | 1997 | 37.9 | low | 2 | 33 | 8 | 0 | 0 | 0 |
| prostaglandin i3 | | prostanoid | | 1983 | 1989 | 37.7 | medium | 0 | 3 | 0 | 0 | 0 | 0 |
| 16,16-dimethylprostaglandin e2 | | cyclopentanones;
monocarboxylic acid;
prostanoid;
secondary allylic alcohol | anti-ulcer drug;
gastrointestinal drug;
radiation protective agent | 1984 | 1994 | 36.9 | low | 0 | 6 | 1 | 0 | 0 | 0 |
| 2,3-dinor-6-ketoprostaglandin f1alpha | | 4-oxo monocarboxylic acid;
prostanoid;
secondary alcohol | metabolite | 1980 | 2018 | 30.6 | high | 39 | 78 | 87 | 24 | 8 | 0 |
| leukotriene b5 | | dihydroxy monocarboxylic acid;
hydroxy polyunsaturated fatty acid;
leukotriene;
long-chain fatty acid | anti-inflammatory agent;
human xenobiotic metabolite;
rat metabolite | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| thromboxane b2 | | thromboxanes B | human metabolite;
mouse metabolite | 1979 | 2021 | 32.8 | high | 177 | 1,103 | 953 | 167 | 62 | 1 |
| 2,3-dinor-thromboxane b2 | | thromboxane | | 1986 | 2009 | 32.3 | high | 12 | 38 | 35 | 7 | 0 | 0 |
| 20-hydroxy-5,8,11,14-eicosatetraenoic acid | | HETE;
hydroxy monocarboxylic acid | human metabolite;
mouse metabolite | 1998 | 2002 | 24.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| arachidonic acid 5-hydroperoxide | | HPETE | human xenobiotic metabolite | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 5,6-epoxy-8,11,14-eicosatrienoic acid | | EET | mouse metabolite | 1991 | 2003 | 26.8 | low | 0 | 0 | 3 | 1 | 0 | 0 |
| 8,9-epoxyeicosatrienoic acid | | EET | mouse metabolite | 1991 | 1997 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| cyproterone | | 17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(4) steroid;
chlorinated steroid;
tertiary alpha-hydroxy ketone | androgen antagonist | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| naloxone | | morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol | antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| sirolimus | | antibiotic antifungal drug;
cyclic acetal;
cyclic ketone;
ether;
macrolide lactam;
organic heterotricyclic compound;
secondary alcohol | antibacterial drug;
anticoronaviral agent;
antineoplastic agent;
bacterial metabolite;
geroprotector;
immunosuppressive agent;
mTOR inhibitor | 1993 | 2009 | 20.3 | low | 1 | 0 | 1 | 2 | 0 | 0 |
| brefeldin a | | macrolide antibiotic | Penicillium metabolite | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| morphine | | morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound | anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic | 1987 | 2008 | 22.5 | low | 1 | 1 | 0 | 3 | 0 | 0 |
| 2-methylthio-atp | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 7-benzylidenenaltrexone | | phenanthrenes | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| acipimox | | pyrazinecarboxylic acid | | 1990 | 1990 | 34.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| ah 23848 | | (4Z)-7-{5-[([1,1'-biphenyl]-4-yl)methoxy]-2-(morpholin-4-yl)-3-oxocyclopentyl}hept-4-enoic acid | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| bay u9773 | | benzoic acids;
dicarboxylic acid;
organic sulfide;
polyunsaturated fatty acid;
secondary alcohol | leukotriene antagonist | 2000 | 2000 | 24.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| cicaprost | | monoterpenoid | | 1992 | 2004 | 24.3 | low | 0 | 0 | 1 | 2 | 0 | 0 |
| clobetasol | | 11beta-hydroxy steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
3-oxo-Delta(1),Delta(4)-steroid;
chlorinated steroid;
fluorinated steroid;
glucocorticoid;
tertiary alpha-hydroxy ketone | anti-inflammatory drug;
SMO receptor agonist | 1981 | 1981 | 43.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| deamino arginine vasopressin | | heterodetic cyclic peptide | diagnostic agent;
renal agent;
vasopressin receptor agonist | 1982 | 2009 | 34.4 | low | 0 | 6 | 3 | 1 | 0 | 0 |
| fr 173657 | | | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| kallidin | | peptide | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| iloprost | | carbobicyclic compound;
monocarboxylic acid;
secondary alcohol | platelet aggregation inhibitor;
vasodilator agent | 1983 | 2009 | 28.5 | low | 2 | 8 | 15 | 11 | 0 | 0 |
| enprostil | | | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| lysophosphatidylcholines | | 1-O-acyl-sn-glycero-3-phosphocholine | | 1989 | 2007 | 25.8 | low | 0 | 1 | 2 | 1 | 0 | 0 |
| cytochalasin b | | cytochalasin;
lactam;
lactone;
organic heterotricyclic compound | actin polymerisation inhibitor;
metabolite;
mycotoxin;
platelet aggregation inhibitor | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| neurokinin a | | | | 1989 | 1993 | 32.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| neurokinin b | | polypeptide | | 1989 | 1993 | 32.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| ono 3708 | | | | 1991 | 2003 | 30.2 | medium | 0 | 0 | 10 | 1 | 0 | 0 |
| pd 123319 | | imidazopyridine | angiotensin receptor antagonist;
endothelin receptor antagonist;
vasoconstrictor agent | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| u 44069 | | prostanoid | | 1984 | 2004 | 33.0 | low | 0 | 2 | 0 | 1 | 0 | 0 |
| rioprostil | | aliphatic alcohol | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| sq 29548 | | | | 1985 | 2012 | 31.5 | low | 0 | 4 | 5 | 0 | 1 | 0 |
| onapristone | | | | 1991 | 1993 | 31.8 | low | 0 | 0 | 4 | 0 | 0 | 0 |
| s 145 | | monoterpenoid | | 1992 | 2000 | 29.2 | low | 0 | 0 | 4 | 0 | 0 | 0 |
| sulprostone | | prostanoid | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 12-hydroxy-8,10-heptadecadienoic acid | | long-chain fatty acid | | 1980 | 1980 | 44.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| 12-hydroxy-5,8,10-heptadecatrienoic acid | | hydroxy polyunsaturated fatty acid;
long-chain fatty acid;
trienoic fatty acid | metabolite | 1981 | 2009 | 33.4 | low | 0 | 5 | 3 | 2 | 0 | 0 |
| erbstatin | | | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ag 556 | | | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ag-490 | | catechols;
enamide;
monocarboxylic acid amide;
nitrile;
secondary carboxamide | anti-inflammatory agent;
antioxidant;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector;
STAT3 inhibitor | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| ag 127 | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sulindac sulfide | | aryl sulfide;
monocarboxylic acid;
organofluorine compound | antineoplastic agent;
apoptosis inducer;
non-steroidal anti-inflammatory drug | 1985 | 1986 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| 11-hydroxy-5,8,12,14-eicosatetraenoic acid | | | | 1982 | 1991 | 36.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| 12-hydroxy-5,8,10,14-eicosatetraenoic acid | | | | 1981 | 2007 | 34.0 | low | 1 | 17 | 13 | 1 | 0 | 0 |
| 15-hydroxy-5,8,11,13-eicosatetraenoic acid | | | | 1982 | 2007 | 32.8 | low | 0 | 6 | 9 | 1 | 0 | 0 |
| 8-hydroxy-11,12-epoxyeicosa-5,9,14-trienoic acid | | | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid | | | | 1979 | 2012 | 29.7 | low | 1 | 10 | 13 | 7 | 1 | 0 |
| rubidium | | alkali metal atom | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| aluminum | | boron group element atom;
elemental aluminium;
metal atom | | 1986 | 1990 | 36.2 | low | 1 | 3 | 1 | 0 | 0 | 0 |
| arsenic | | metalloid atom;
pnictogen | micronutrient | 1986 | 1992 | 34.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| indium | | boron group element atom | | 1983 | 1987 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| naltrexone | | cyclopropanes;
morphinane-like compound;
organic heteropentacyclic compound | antidote to opioid poisoning;
central nervous system depressant;
environmental contaminant;
mu-opioid receptor antagonist;
xenobiotic | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| lisinopril | | dipeptide | EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor | 1990 | 1996 | 31.3 | low | 1 | 0 | 3 | 0 | 0 | 0 |
| ramipril | | azabicycloalkane;
cyclopentapyrrole;
dicarboxylic acid monoester;
dipeptide;
ethyl ester | bradykinin receptor B2 agonist;
cardioprotective agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
matrix metalloproteinase inhibitor;
prodrug | 1986 | 2017 | 26.0 | low | 1 | 2 | 3 | 2 | 1 | 0 |
| ridogrel | | (trifluoromethyl)benzenes | | 1990 | 2001 | 30.0 | medium | 0 | 0 | 9 | 1 | 0 | 0 |
| sulfur | | chalcogen;
nonmetal atom | macronutrient | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| musk | | macrolide | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| puerarin | | C-glycosyl compound;
isoflavonoid | | 1990 | 2012 | 23.0 | low | 1 | 0 | 1 | 0 | 1 | 0 |
| 7-hydroxymethotrexate | | folic acids | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| enalapril | | dicarboxylic acid monoester;
dipeptide | antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
geroprotector;
prodrug | 1985 | 2007 | 30.0 | low | 6 | 6 | 6 | 4 | 0 | 0 |
| cysteine | | cysteinium | fundamental metabolite | 1988 | 2006 | 24.5 | low | 0 | 1 | 2 | 3 | 0 | 0 |
| silicon | | carbon group element atom;
metalloid atom;
nonmetal atom | | 1982 | 1985 | 40.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| enalaprilat anhydrous | | dicarboxylic acid;
dipeptide | antihypertensive agent;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor | 1989 | 1989 | 35.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| ramiprilat | | azabicycloalkane;
cyclopentapyrrole;
dicarboxylic acid;
dipeptide | bradykinin receptor B2 agonist;
cardioprotective agent;
drug metabolite;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
matrix metalloproteinase inhibitor | 1993 | 2005 | 26.7 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| ay 25,205 | | | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| methoxysuccinyl-alanyl-alanyl-prolyl-valine chloromethyl ketone | | alpha-chloroketone;
methyl ester;
tripeptide | EC 3.4.21.37 (leukocyte elastase) inhibitor | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| oxyfedrine | | aromatic ketone | | 1988 | 1996 | 32.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| triolein | | triglyceride | Caenorhabditis elegans metabolite;
plant metabolite | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| ono 1301 | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| saralasin | | oligopeptide | | 1984 | 1999 | 35.7 | low | 0 | 5 | 2 | 0 | 0 | 0 |
| tetrodotoxin | | azatetracycloalkane;
oxatetracycloalkane;
quinazoline alkaloid | animal metabolite;
bacterial metabolite;
marine metabolite;
neurotoxin;
voltage-gated sodium channel blocker | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| selenium | | chalcogen;
nonmetal atom | micronutrient | 1984 | 2007 | 31.1 | low | 1 | 5 | 8 | 2 | 0 | 0 |
| aluminum hydroxide, magnesium hydroxide, drug combination | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| maxacalcitol | | organic molecular entity | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| dizocilpine maleate | | maleate salt;
tetracyclic antidepressant | anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist | 1993 | 1994 | 30.3 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| pregnanediol | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cilastatin | | carboxamide;
L-cysteine derivative;
non-proteinogenic L-alpha-amino acid;
organic sulfide | EC 3.4.13.19 (membrane dipeptidase) inhibitor;
environmental contaminant;
protease inhibitor;
xenobiotic | 1994 | 1994 | 30.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| 6-(4-(2-(((4-chlorophenyl)sulfonyl)amino)ethyl)phenyl)-6-(3-pyridyl)hex-5-enoic acid | | | | 2000 | 2002 | 23.0 | high | 0 | 0 | 1 | 1 | 0 | 0 |
| carboprostacyclin | | prostanoid | | 1985 | 2009 | 29.8 | low | 0 | 1 | 2 | 1 | 0 | 0 |
| 1-oleoyl-2-acetylglycerol | | 1,2-diglyceride | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid | | HPETE | human xenobiotic metabolite | 1980 | 1987 | 41.8 | low | 0 | 5 | 0 | 0 | 0 | 0 |
| linoleylanilide | | anilide;
fatty amide | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| manoalide | | butenolide;
lactol;
sesterterpenoid | EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
metabolite | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| piriprost | | | | 1986 | 1987 | 37.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| 2-methyl-3-(4-(3-pyridinylmethyl)phenyl)-2-propenoic acid | | | | 1981 | 1990 | 39.7 | medium | 0 | 16 | 1 | 0 | 0 | 0 |
| bwa 4c | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 7-oxoprostaglandin i2 | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| op 2507 | | | | 1994 | 2006 | 25.4 | medium | 0 | 0 | 3 | 2 | 0 | 0 |
| limaprost | | long-chain fatty acid | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 19-hydroxyprostaglandin e1 | | | | 1979 | 1979 | 45.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| u 75412e | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| l 651896 | | | | 1989 | 1989 | 35.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| 13,14-dihydroxy-15-ketoprostaglandin f2alpha | | | | 1988 | 1988 | 36.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| ono 8809 | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| op 41483-alpha-cyclodextrin | | | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| 5,6-dihydroprostacyclin | | | | 1979 | 1989 | 40.0 | medium | 0 | 2 | 0 | 0 | 0 | 0 |
| 9-hydroxy-11,15-dioxo-2,3,18,19-tetranorprost-5-ene-1,20-dioic acid | | | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 11-dehydro-2,3-dinor-thromboxane b2 | | | | 2007 | 2007 | 17.0 | medium | 1 | 0 | 0 | 1 | 0 | 0 |
| terbogrel | | diterpene glycoside | | 2004 | 2004 | 20.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| verlukast | | | | 1998 | 2000 | 24.7 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| isbogrel | | | | 1986 | 1996 | 33.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| beta-escin | | | | 1986 | 2022 | 21.1 | low | 1 | 1 | 6 | 0 | 5 | 1 |
| s-nitroso-n-acetylpenicillamine | | nitroso compound;
nitrosothio compound | nitric oxide donor;
vasodilator agent | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ergoline | | diamine;
ergoline alkaloid;
indole alkaloid fundamental parent;
indole alkaloid;
organic heterotetracyclic compound | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| adenosine-3',5'-cyclic phosphorothioate | | nucleoside 3',5'-cyclic phosphorothioate | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| sq-23377 | | cyclic ether;
enol;
polyunsaturated fatty acid;
very long-chain fatty acid | calcium ionophore;
metabolite | 1988 | 1997 | 32.7 | low | 0 | 2 | 5 | 0 | 0 | 0 |
| tomoxiprole | | | | 1984 | 1984 | 40.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| beraprost | | enyne;
monocarboxylic acid;
organic heterotricyclic compound;
secondary alcohol;
secondary allylic alcohol | anti-inflammatory agent;
antihypertensive agent;
platelet aggregation inhibitor;
prostaglandin receptor agonist;
vasodilator agent | 1996 | 2012 | 22.4 | low | 1 | 0 | 4 | 2 | 1 | 0 |
| vapiprost | | | | 1989 | 2000 | 28.2 | low | 0 | 1 | 5 | 0 | 0 | 0 |
| u 62840 | | carbotricyclic compound;
carboxylic acid | antihypertensive agent;
cardiovascular drug;
human blood serum metabolite;
platelet aggregation inhibitor;
vasodilator agent;
vitamin K antagonist | 2021 | 2021 | 3.0 | low | 0 | 0 | 0 | 0 | 0 | 1 |
| hexarelin | | | | 1997 | 2000 | 25.5 | low | 0 | 0 | 6 | 0 | 0 | 0 |
| staurosporine | | ammonium ion derivative | | 1990 | 1996 | 30.2 | low | 0 | 0 | 5 | 0 | 0 | 0 |
| ep 045 | | | | 1984 | 1985 | 39.5 | medium | 0 | 2 | 0 | 0 | 0 | 0 |
| l 745337 | | | | 1997 | 1998 | 26.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| ono4819 | | benzyl ether | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| ono 8711 | | | | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| sincalide | | oligopeptide | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cg100649 | | | | 2012 | 2012 | 12.0 | low | 1 | 0 | 0 | 0 | 1 | 0 |
| pentagastrin | | organic molecular entity | | 1980 | 1989 | 38.8 | low | 1 | 4 | 0 | 0 | 0 | 0 |
| mocetinostat | | aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline | antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent | 1987 | 2017 | 24.0 | low | 0 | 3 | 11 | 11 | 1 | 0 |
| sc 236 | | | | 1999 | 2001 | 23.7 | low | 0 | 0 | 1 | 2 | 0 | 0 |
| ticagrelor | | aryl sulfide;
hydroxyether;
organofluorine compound;
secondary amino compound;
triazolopyrimidines | P2Y12 receptor antagonist;
platelet aggregation inhibitor | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| lipid a | | dodecanoate ester;
lipid A;
tetradecanoate ester | Escherichia coli metabolite | 1988 | 1988 | 36.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| psd 502 | | | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| mre 269 | | aromatic amine;
ether;
monocarboxylic acid;
pyrazines;
sulfonamide;
tertiary amino compound | drug metabolite;
orphan drug;
platelet aggregation inhibitor;
prostacyclin receptor agonist;
vasodilator agent | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| g(m1) ganglioside | | alpha-N-acetylneuraminosyl-(2->3)-[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)]-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphingosine;
sialotetraosylceramide | | 1988 | 1994 | 33.0 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| 4-hydroxyestrone | | 17-oxo steroid;
3-hydroxy steroid;
4-hydroxy steroid;
catechols;
phenolic steroid | carcinogenic agent;
estrogen;
human urinary metabolite | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| n-(1-methylethyl)-1,1,2-trimethylpropylamine | | | | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| bismuth tripotassium dicitrate | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| tribulus | | | | 2011 | 2011 | 13.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| ro3244794 | | | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| oxadiazoles | | | | 1983 | 2017 | 25.3 | low | 0 | 2 | 1 | 2 | 1 | 0 |
| ucn 1028 c | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| 2-chlorohexadecanoic acid | | | | 2008 | 2008 | 16.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 |
| palytoxin | | polyol | toxin | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| linoleic acid hydroperoxide | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| losartan potassium | | | | 1994 | 2005 | 24.8 | low | 0 | 0 | 2 | 2 | 0 | 0 |
| norgestimate | | | | 1995 | 1995 | 29.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| calcimycin | | benzoxazole | | 1980 | 2004 | 34.9 | low | 0 | 74 | 57 | 3 | 0 | 0 |
| indocyanine green | | 1,1-diunsubstituted alkanesulfonate;
benzoindole;
cyanine dye | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| pituitrin | | | | 1983 | 1998 | 34.8 | low | 1 | 7 | 5 | 0 | 0 | 0 |
| 2-(4-(3-methyl-2-thienyl)phenyl)propionic acid | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| acid phosphatase | | | | 1986 | 1990 | 36.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| ataprost | | | | 1991 | 1996 | 30.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| butaprost | | | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| icatibant | | | | 1992 | 2006 | 25.3 | low | 1 | 0 | 5 | 2 | 0 | 0 |
| nad | | organophosphate oxoanion | cofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite | 1978 | 1989 | 41.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| tin mesoporphyrin | | | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| mf63 compound | | | | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| cosyntropin | | | | 1982 | 1985 | 40.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| melitten | | | | 1983 | 1996 | 35.7 | low | 0 | 5 | 2 | 0 | 0 | 0 |
| ceruletide | | oligopeptide | diagnostic agent;
gastrointestinal drug | 1992 | 2006 | 27.0 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| motilin | | | | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| atrial natriuretic factor | | polypeptide | | 1985 | 2015 | 28.9 | low | 8 | 9 | 16 | 3 | 3 | 0 |
| thrombin receptor peptide (42-55) | | | | 1991 | 2004 | 26.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| fibrinopeptide b | | | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| gastrins | | | | 1986 | 2007 | 27.3 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| glucagon | | peptide hormone | | 1983 | 2001 | 32.0 | low | 2 | 4 | 3 | 1 | 0 | 0 |
| beta-endorphin | | | | 1992 | 1998 | 29.0 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| neuropeptide y | | | | 1988 | 1997 | 32.0 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| s6c sarafotoxin | | | | 1993 | 1995 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| iberiotoxin | | | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| angiotensinogen | | | | 2001 | 2005 | 21.0 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| irl 1620 | | | | 1995 | 1997 | 28.3 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| cyn 154806 | | | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| c-peptide | | | | 1985 | 2002 | 30.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| natriuretic peptide, c-type | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cellulose | | glycoside | | 1985 | 1991 | 36.3 | low | 1 | 2 | 1 | 0 | 0 | 0 |
| endothelin-1 | | | | 1994 | 2020 | 21.2 | low | 10 | 0 | 37 | 29 | 14 | 0 |
| phosphatidylcholines | | 1,2-diacyl-sn-glycero-3-phosphocholine | | 1985 | 1999 | 32.4 | low | 2 | 3 | 5 | 0 | 0 | 0 |
| (9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one | | 21-hydroxy steroid | | 1996 | 1996 | 28.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| thimerosal | | alkylmercury compound | antifungal drug;
antiseptic drug;
disinfectant;
drug allergen | 1992 | 2000 | 28.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| sodium salicylate | | organic molecular entity | | 1985 | 2001 | 32.5 | low | 0 | 2 | 1 | 1 | 0 | 0 |
| ubiquinone | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| calpain | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| hoe k86-4321 | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| menotropins | | | | 1985 | 1987 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| bucladesine | | 3',5'-cyclic purine nucleotide | | 1983 | 2004 | 33.3 | low | 0 | 10 | 8 | 2 | 0 | 0 |
| rs 5186 | | | | 1991 | 1994 | 31.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| y 20811 | | | | 1986 | 1992 | 34.8 | medium | 0 | 2 | 2 | 0 | 0 | 0 |
| r 59274 | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cortisol succinate, sodium salt | | organic molecular entity | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| s-adenosylmethionine | | organic cation;
sulfonium compound | coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| albiflorin | | benzoate ester;
beta-D-glucoside;
bridged compound;
gamma-lactone;
monoterpene glycoside;
secondary alcohol | neuroprotective agent;
plant metabolite | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| cardiovascular agents | | | | 1987 | 2014 | 24.0 | low | 1 | 2 | 0 | 3 | 1 | 0 |
| neurotensin | | peptide hormone | human metabolite;
mitogen;
neurotransmitter;
vulnerary | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| fibrinopeptide a | | | | 1985 | 1994 | 35.2 | low | 4 | 3 | 3 | 0 | 0 | 0 |
| mannans | | | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| aspirin eugenol ester | | | | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| 3,4-oxoisopropylideneshikimic acid | | | | 2003 | 2003 | 21.0 | medium | 0 | 0 | 0 | 1 | 0 | 0 |
| 11,12-epoxy-5,8,14-eicosatrienoic acid | | 11,12-EET | human xenobiotic metabolite | 1991 | 2005 | 26.3 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| 2-chlorohexadecanal | | | | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| glycolipids | | | | 1985 | 1988 | 37.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| piperidines | | | | 1984 | 2016 | 21.7 | low | 2 | 1 | 4 | 6 | 2 | 0 |
| interleukin-8 | | | | 1997 | 2014 | 21.3 | low | 0 | 0 | 3 | 3 | 1 | 0 |
| myrtucommulone a | | aromatic ketone | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| fosinopril | | | | 1991 | 1999 | 29.0 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| aplysiatoxin | | aplysiatoxins;
bromophenol;
cyclic hemiketal;
ether;
organic heterotricyclic compound;
secondary alcohol;
spiroketal | algal metabolite;
carcinogenic agent;
cyanotoxin;
marine metabolite;
protein kinase C agonist | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| isoquercitrin | | | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| vasoactive intestinal peptide | | | | 1984 | 2014 | 27.0 | low | 0 | 1 | 2 | 0 | 1 | 0 |
| heme | | | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| heparitin sulfate | | | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| tuftsin | | peptide | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ascorbic acid | | ascorbic acid;
vitamin C | coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent | 1981 | 2004 | 37.7 | low | 0 | 5 | 0 | 1 | 0 | 0 |
| minocycline | | | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| salicylates | | monohydroxybenzoate | plant metabolite | 1983 | 1998 | 34.4 | low | 4 | 7 | 9 | 0 | 0 | 0 |
| piroxicam | | benzothiazine;
monocarboxylic acid amide;
pyridines | analgesic;
antirheumatic drug;
cyclooxygenase 1 inhibitor;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug | 1984 | 1996 | 35.4 | low | 4 | 8 | 4 | 0 | 0 | 0 |
| mobic | | 1,3-thiazoles;
benzothiazine;
monocarboxylic acid amide | analgesic;
antirheumatic drug;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug | 1999 | 2008 | 22.6 | low | 1 | 0 | 4 | 1 | 0 | 0 |
| isoxicam | | benzothiazine;
isoxazoles;
monocarboxylic acid amide | antirheumatic drug;
non-steroidal anti-inflammatory drug | 1989 | 1989 | 35.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| warfarin | | benzenes;
hydroxycoumarin;
methyl ketone | | 1982 | 1993 | 37.0 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| teriflunomide | | (trifluoromethyl)benzenes;
aromatic amide;
enamide;
enol;
nitrile;
secondary carboxamide | drug metabolite;
EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor;
hepatotoxic agent;
non-steroidal anti-inflammatory drug;
tyrosine kinase inhibitor | 1998 | 1999 | 25.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| epidermal growth factor | | | | 1985 | 2005 | 32.1 | low | 0 | 9 | 7 | 2 | 0 | 0 |
| kaolinite | | aluminosilicate mineral;
mixture | antidiarrhoeal drug;
excipient | 1989 | 1996 | 31.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| transforming growth factor beta | | | | 1993 | 2011 | 26.0 | low | 0 | 0 | 7 | 1 | 1 | 0 |
| okadaic acid | | ketal | | 1988 | 1996 | 32.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| tcv 309 | | | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| phosphatidylethanol | | | | 1992 | 1997 | 29.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| lipoxin b4 | | hydroxy fatty acid anion;
lipoxin anion | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| kiss1 protein, human | | | | 2015 | 2015 | 9.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| hirudin | | | | 1987 | 1999 | 31.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| caseins | | | | 1991 | 2003 | 27.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| limbrel | | | | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| oligomycins | | | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| asbestos, crocidolite | | | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| g(m3) ganglioside | | alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide;
sialodiosylceramide;
sialotriaosylceramide | mouse metabolite | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| nitrophenols | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| hydroxytyrosyl acetate | | | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| 1 alpha,24-dihydroxyvitamin d3 | | | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| angiotensin i | | angiotensin;
peptide zwitterion | human metabolite;
neurotransmitter agent | 1986 | 2015 | 27.5 | low | 0 | 1 | 6 | 2 | 1 | 0 |
| siagoside | | lactone;
sialotetraosylceramide | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| hyaluronoglucosaminidase | | | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| adrenomedullin | | | | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| angiotensin iii | | | | 1983 | 1994 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| sta 2 | | | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| ginkgolide b | | | | 1989 | 2002 | 30.7 | low | 0 | 1 | 8 | 1 | 0 | 0 |
| neferine | | | | 1995 | 1997 | 28.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| t-2 toxin | | | | 1985 | 1986 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| peoniflorin | | | | 2014 | 2017 | 8.5 | low | 0 | 0 | 0 | 0 | 2 | 0 |
| vitamin b 12 | | | | 2019 | 2019 | 5.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| norgestrel | | | | 1984 | 1995 | 34.8 | low | 1 | 2 | 2 | 0 | 0 | 0 |
| transforming growth factor alpha | | | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| cyclosporine | | | | 1991 | 2018 | 26.6 | low | 7 | 0 | 22 | 7 | 1 | 0 |
| apyrase | | | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| thromboplastin | | | | 1987 | 2015 | 23.7 | low | 0 | 2 | 1 | 2 | 1 | 0 |
| muramidase | | | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| chondroitin sulfates | | | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| cyclic gmp | | 3',5'-cyclic purine nucleotide;
guanyl ribonucleotide | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite | 1982 | 2013 | 28.5 | low | 4 | 9 | 43 | 11 | 1 | 0 |
| guanosine monophosphate | | guanosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate | biomarker;
Escherichia coli metabolite;
metabolite;
mouse metabolite | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| guanosine triphosphate | | guanosine 5'-phosphate;
purine ribonucleoside 5'-triphosphate | Escherichia coli metabolite;
mouse metabolite;
uncoupling protein inhibitor | 1984 | 2000 | 32.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| guanine | | 2-aminopurines;
oxopurine;
purine nucleobase | algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| hypoxanthine | | nucleobase analogue;
oxopurine;
purine nucleobase | fundamental metabolite | 1987 | 1987 | 37.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| inosine | | inosines;
purines D-ribonucleoside | Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite | 1987 | 1987 | 37.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| folic acid | | folic acids;
N-acyl-amino acid | human metabolite;
mouse metabolite;
nutrient | 2019 | 2019 | 5.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| guanosine 5'-o-(3-thiotriphosphate) | | nucleoside triphosphate analogue | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| zaprinast | | triazolopyrimidines | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| allopurinol | | nucleobase analogue;
organic heterobicyclic compound | antimetabolite;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
gout suppressant;
radical scavenger | 1989 | 2008 | 27.1 | low | 1 | 2 | 6 | 4 | 0 | 0 |
| 2,2'-(hydroxynitrosohydrazono)bis-ethanamine | | | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| guanylyl imidodiphosphate | | nucleoside triphosphate analogue | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| bw 540c | | | | 1987 | 1987 | 37.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| 8-bromocyclic gmp | | 3',5'-cyclic purine nucleotide;
organobromine compound | muscle relaxant;
protein kinase G agonist | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| trypan blue | | | | 1992 | 1996 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| coelenterazine | | | | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| n,n'-monomethylenebis(pyridiniumaldoxime) | | | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| defibrotide | | | | 1986 | 2000 | 32.2 | low | 1 | 4 | 10 | 0 | 0 | 0 |
| flm 5011 | | | | 1988 | 1988 | 36.0 | medium | 0 | 1 | 0 | 0 | 0 | 0 |
| eye | | | | 1984 | 1987 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| acetylcellulose | | | | 1991 | 1991 | 33.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| concanavalin a | | | | 1988 | 1991 | 34.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| metallothionein | | | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| leptin | | | | 2001 | 2006 | 20.5 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| pyrimidinones | | | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| tetrafluoroaluminate | | | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| filipin | | | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| phenanthrenes | | | | 1996 | 2016 | 20.0 | low | 0 | 0 | 2 | 0 | 1 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|
| 47,XX,+21 | 0 | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Abdominal Aortic Aneurysm | 0 | | 2012 | 2012 | 12.0 | low | 1 | 0 | 0 | 0 | 1 | 0 |
| Abdominal Migraine | 0 | | 1985 | 2007 | 33.0 | low | 0 | 5 | 1 | 1 | 0 | 0 |
| Abdominal Pain | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Abnormality, Heart | 0 | | 1987 | 2010 | 28.2 | low | 0 | 1 | 2 | 1 | 0 | 0 |
| Abortion, Habitual | 0 | | 1983 | 1997 | 33.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Abortion, Recurrent | 0 | | 1983 | 1997 | 33.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Abortion, Spontaneous | 0 | | 1985 | 1993 | 35.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Abortion, Tubal | 0 | | 1985 | 1993 | 35.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Abortion, Veterinary | 0 | | 1985 | 2009 | 27.0 | low | 1 | 1 | 0 | 1 | 0 | 0 |
| Abruptio Placentae | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Abscess | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Abscess, Periapical | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Absence Seizure | 0 | | 1998 | 2014 | 18.0 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| ACD-MPV | 0 | | 1990 | 1991 | 33.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Ache | 0 | | 1984 | 2016 | 26.2 | low | 1 | 2 | 5 | 1 | 1 | 0 |
| Acidosis | 0 | | 1992 | 1998 | 29.8 | low | 0 | 0 | 5 | 0 | 0 | 0 |
| Acidosis, Diabetic | 0 | | 1982 | 1996 | 36.4 | low | 1 | 6 | 3 | 0 | 0 | 0 |
| Acquired Nephrogenic Diabetes Insipidus | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Active Hyperemia | 0 | | 1981 | 2013 | 31.2 | low | 0 | 4 | 5 | 1 | 1 | 0 |
| Acute Bacterial Prostatitis | 0 | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Acute Brain Injuries | 0 | | 1987 | 2013 | 25.7 | low | 1 | 3 | 1 | 0 | 2 | 0 |
| Acute Confusional Senile Dementia | 0 | | 2010 | 2010 | 14.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Acute Disease | 0 | | 1980 | 2009 | 32.7 | low | 4 | 22 | 22 | 5 | 0 | 0 |
| Acute Edematous Pancreatitis | 0 | | 1985 | 2007 | 31.2 | low | 0 | 5 | 10 | 2 | 0 | 0 |
| Acute Hepatic Failure | 0 | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Acute Hypercapnic Respiratory Failure | 0 | | 1984 | 1991 | 36.6 | low | 0 | 5 | 2 | 0 | 0 | 0 |
| Acute Kidney Failure | 0 | | 1981 | 2015 | 33.3 | low | 0 | 16 | 2 | 1 | 2 | 0 |
| Acute Kidney Injury | 0 | | 1981 | 2015 | 33.3 | low | 0 | 16 | 2 | 1 | 2 | 0 |
| Acute Kidney Tubular Necrosis | 0 | | 1987 | 1998 | 33.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Acute Liver Injury, Drug-Induced | 0 | | 1990 | 2010 | 27.2 | low | 0 | 0 | 4 | 1 | 0 | 0 |
| Acute Lymphoid Leukemia | 0 | | 1988 | 1994 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Acute Myelogenous Leukemia | 0 | | 1987 | 1994 | 34.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Acute Necrotizing Pancreatitis | 0 | | 1997 | 2013 | 21.0 | low | 0 | 0 | 2 | 2 | 1 | 0 |
| Acute Post-operative Pain | 0 | | 1987 | 2008 | 24.3 | low | 3 | 1 | 0 | 2 | 0 | 0 |
| Acute Respiratory Distress Syndrome | 0 | | 1984 | 2004 | 30.9 | low | 3 | 10 | 14 | 2 | 0 | 0 |
| Acute-Phase Reaction | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Adamantiades-Behcet Disease | 0 | | 1984 | 1986 | 39.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Addison Disease and Cerebral Sclerosis | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Adenocarcinoma | 0 | | 1983 | 2002 | 31.1 | low | 1 | 5 | 2 | 3 | 0 | 0 |
| Adenocarcinoma Of Kidney | 0 | | 1998 | 2010 | 20.0 | low | 1 | 0 | 1 | 1 | 0 | 0 |
| Adenocarcinoma, Basal Cell | 0 | | 1983 | 2002 | 31.1 | low | 1 | 5 | 2 | 3 | 0 | 0 |
| Adenoma | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Adenoma, Basal Cell | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Adenoma, beta-Cell | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Adenoma, Prostatic | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Adenomatous Polyposis Coli | 0 | | 1998 | 2012 | 20.7 | low | 0 | 0 | 2 | 0 | 1 | 0 |
| Adenomatous Polyposis Coli, Familial | 0 | | 1998 | 2012 | 20.7 | low | 0 | 0 | 2 | 0 | 1 | 0 |
| Adhesions, Tissue | 0 | | 1982 | 1992 | 36.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Adjuvant Arthritis | 0 | | 1985 | 2016 | 23.5 | low | 0 | 1 | 0 | 0 | 1 | 0 |
| Adnexitis | 0 | | 1984 | 1986 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| ADPKD | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Adrenoleukodystrophy | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Agenesis of Hemidiaphragm | 0 | | 1984 | 1992 | 36.2 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| Aging | 0 | | 1981 | 2015 | 34.3 | low | 0 | 31 | 18 | 5 | 1 | 0 |
| Agnogenic Myeloid Metaplasia | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Agoraphobia | 0 | | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| Agranulocytosis | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| AIDS Seroconversion | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Air Embolism | 0 | | 1986 | 1987 | 37.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Airflow Obstruction, Chronic | 0 | | 2012 | 2012 | 12.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Airway Hyper-Responsiveness | 0 | | 1988 | 1993 | 33.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Albuminuria | 0 | | 1989 | 2013 | 27.8 | low | 0 | 1 | 8 | 2 | 1 | 0 |
| Alcohol Abuse | 0 | | 1987 | 1988 | 36.6 | low | 0 | 5 | 0 | 0 | 0 | 0 |
| Alcohol Drinking | 0 | | 1987 | 2008 | 29.8 | low | 1 | 2 | 2 | 1 | 0 | 0 |
| Alcohol Related Neurodevelopmental Disorder | 0 | | 1988 | 2008 | 28.0 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Alcoholic Cirrhosis | 0 | | 1986 | 2014 | 27.8 | low | 0 | 2 | 1 | 0 | 1 | 0 |
| Alcoholic Hepatitis | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Alcoholic Intoxication | 0 | | 1984 | 2000 | 33.7 | low | 1 | 2 | 1 | 0 | 0 | 0 |
| Alcoholic Liver Diseases | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Alcoholism | 0 | | 1987 | 1988 | 36.6 | low | 0 | 5 | 0 | 0 | 0 | 0 |
| Aldosteronism | 0 | | 1980 | 1986 | 41.8 | low | 0 | 8 | 0 | 0 | 0 | 0 |
| Aldosteronism with Hyperplasia of the Adrenal Cortex | 0 | | 1980 | 2005 | 37.2 | low | 1 | 9 | 1 | 2 | 0 | 0 |
| Alkalosis | 0 | | 1986 | 1989 | 36.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Allergic Conjunctivitis | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Allergic Encephalomyelitis | 0 | | 1984 | 1986 | 39.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Allergic Reaction | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Allodynia | 0 | | 1989 | 2006 | 26.5 | low | 1 | 1 | 1 | 2 | 0 | 0 |
| Alloxan Diabetes | 0 | | 1981 | 2015 | 32.1 | low | 0 | 39 | 23 | 4 | 5 | 0 |
| Altitude Hypoxia | 0 | | 1989 | 2007 | 26.0 | low | 1 | 1 | 0 | 1 | 0 | 0 |
| Altitude Sickness | 0 | | 1989 | 2007 | 26.0 | low | 1 | 1 | 0 | 1 | 0 | 0 |
| Alveolar Bone Atrophy | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Alveolitis, Fibrosing | 0 | | 1982 | 1994 | 37.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Alzheimer Disease | 0 | | 2010 | 2010 | 14.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Ameloblastoma | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Anaphylactic Reaction | 0 | | 1983 | 1997 | 35.2 | low | 0 | 7 | 6 | 0 | 0 | 0 |
| Anaphylaxis | 0 | | 1983 | 1997 | 35.2 | low | 0 | 7 | 6 | 0 | 0 | 0 |
| Anaplastic Astrocytoma | 0 | | 1984 | 1998 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Anasarca | 0 | | 1981 | 2006 | 32.7 | low | 0 | 7 | 7 | 1 | 0 | 0 |
| Anemia, Aplastic | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Anemia, Hemolytic | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Anemia, Hemolytic, Acquired | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Anemia, Hypoplastic | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Anemia, Sickle Cell | 0 | | 1982 | 2017 | 31.1 | low | 0 | 5 | 4 | 1 | 1 | 0 |
| Anesthesia | 0 | | 1980 | 2019 | 32.5 | low | 0 | 11 | 3 | 2 | 1 | 0 |
| Aneurysm, Anterior Cerebral Artery | 0 | | 1985 | 1994 | 36.1 | low | 0 | 7 | 2 | 0 | 0 | 0 |
| Aneurysm, Aortic | 0 | | 1981 | 1989 | 38.3 | low | 1 | 3 | 0 | 0 | 0 | 0 |
| Angiitis | 0 | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Angina at Rest | 0 | | 1986 | 2004 | 33.8 | low | 2 | 7 | 3 | 1 | 0 | 0 |
| Angina Pectoris | 0 | | 1981 | 2010 | 35.2 | low | 8 | 25 | 13 | 1 | 0 | 0 |
| Angina Pectoris, Variant | 0 | | 1985 | 1985 | 39.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Angina, Unstable | 0 | | 1986 | 2004 | 33.8 | low | 2 | 7 | 3 | 1 | 0 | 0 |
| Angioblastic Meningioma | 0 | | 1984 | 1993 | 34.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Angioedema | 0 | | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Angiogenesis, Pathologic | 0 | | 1993 | 2014 | 20.8 | low | 1 | 0 | 2 | 1 | 2 | 0 |
| Angiohemophilia | 0 | | 1987 | 1990 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Angioneurotic Edema | 0 | | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Angiospasm, Intracranial | 0 | | 2012 | 2012 | 12.0 | low | 1 | 0 | 0 | 0 | 1 | 0 |
| Angor Pectoris | 0 | | 1981 | 2010 | 35.2 | low | 8 | 25 | 13 | 1 | 0 | 0 |
| Anoxemia | 0 | | 1981 | 2009 | 32.0 | low | 0 | 30 | 24 | 10 | 0 | 0 |
| Anoxia-Ischemia, Brain | 0 | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Anoxia, Brain | 0 | | 1987 | 1996 | 33.0 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| Anoxia, Fetal | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| ANS (Autonomic Nervous System) Diseases | 0 | | 1985 | 1987 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Anterior Choroidal Artery Infarction | 0 | | 1988 | 2015 | 26.2 | low | 2 | 2 | 8 | 0 | 3 | 0 |
| Anterior Circulation Transient Ischemic Attack | 0 | | 1985 | 1999 | 34.9 | low | 0 | 15 | 9 | 0 | 0 | 0 |
| Anti-Phospholipid Antibody Syndrome | 0 | | 1991 | 1997 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Antibiotic-Associated Colitis | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Antiphospholipid Syndrome | 0 | | 1991 | 1997 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Aortic Aneurysm | 0 | | 1981 | 1989 | 38.3 | low | 1 | 3 | 0 | 0 | 0 | 0 |
| Aortic Aneurysm, Abdominal | 0 | | 2012 | 2012 | 12.0 | low | 1 | 0 | 0 | 0 | 1 | 0 |
| Aortic Coarctation | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Aortic Diseases | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Aortic Stenosis | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Aortic Valve Stenosis | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Aortitis Syndrome | 0 | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Aphakia | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Aphthae | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Apnea | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Apnea, Obstructive Sleep | 0 | | 2004 | 2016 | 12.7 | low | 1 | 0 | 0 | 1 | 2 | 0 |
| Apnea, Sleep | 0 | | 1991 | 1998 | 29.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Apolipoprotein B-100, Familial Defective | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Apoplexy | 0 | | 2000 | 2015 | 14.5 | low | 1 | 0 | 1 | 1 | 2 | 0 |
| Aqueductal Stenosis | 0 | | 1986 | 1991 | 34.8 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| Arrhythmia | 0 | | 1984 | 2000 | 34.6 | low | 0 | 9 | 8 | 0 | 0 | 0 |
| Arrhythmias, Cardiac | 0 | | 1984 | 2000 | 34.6 | low | 0 | 9 | 8 | 0 | 0 | 0 |
| Arterial Diseases, Carotid | 0 | | 1984 | 2009 | 29.8 | low | 0 | 3 | 0 | 2 | 0 | 0 |
| Arterial Obstructive Diseases | 0 | | 1981 | 2007 | 32.6 | low | 3 | 7 | 6 | 3 | 0 | 0 |
| Arterial Occlusive Diseases | 0 | | 1981 | 2007 | 32.6 | low | 3 | 7 | 6 | 3 | 0 | 0 |
| Arteriosclerosis | 0 | | 1982 | 2007 | 33.0 | low | 5 | 31 | 15 | 7 | 0 | 0 |
| Arteriosclerosis Obliterans | 0 | | 1981 | 1989 | 39.0 | low | 0 | 6 | 0 | 0 | 0 | 0 |
| Arteriosclerosis, Coronary | 0 | | 1987 | 2012 | 23.9 | low | 1 | 1 | 3 | 4 | 2 | 0 |
| Arthritides, Bacterial | 0 | | 1982 | 1984 | 41.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Arthritis | 0 | | 1989 | 1998 | 30.0 | low | 3 | 1 | 3 | 0 | 0 | 0 |
| Arthritis, Degenerative | 0 | | 1991 | 2004 | 26.5 | low | 1 | 0 | 3 | 1 | 0 | 0 |
| Arthritis, Juvenile | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Arthritis, Juvenile Chronic | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Arthritis, Rheumatoid | 0 | | 1981 | 2001 | 35.0 | low | 3 | 11 | 8 | 1 | 0 | 0 |
| Arthropathies | 0 | | 1992 | 1996 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Arthus Phenomenon | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Ascites | 0 | | 1986 | 1986 | 38.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Aseptic Necrosis of Femur Head | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Asphyxia | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Asphyxia Neonatorum | 0 | | 1989 | 2003 | 29.0 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Aspiration, Meconium | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Asthma | 0 | | 1980 | 2018 | 31.2 | low | 5 | 6 | 17 | 0 | 1 | 0 |
| Asthma, Bronchial | 0 | | 1980 | 2018 | 31.2 | low | 5 | 6 | 17 | 0 | 1 | 0 |
| Asthma, Exercise-Induced | 0 | | 1989 | 1991 | 34.0 | low | 1 | 1 | 1 | 0 | 0 | 0 |
| Astrocytoma | 0 | | 1984 | 1998 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Astrocytoma, Grade IV | 0 | | 1984 | 1998 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Asymmetric Diabetic Proximal Motor Neuropathy | 0 | | 1987 | 2001 | 30.6 | low | 0 | 2 | 4 | 1 | 0 | 0 |
| Asystole | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Atelectasis | 0 | | 1985 | 1992 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Atherogenesis | 0 | | 2009 | 2015 | 13.1 | low | 1 | 0 | 0 | 5 | 4 | 0 |
| Atheroma | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Atherosclerosis | 0 | | 2009 | 2015 | 13.1 | low | 1 | 0 | 0 | 5 | 4 | 0 |
| Atopic Hypersensitivity | 0 | | 1981 | 2002 | 34.8 | low | 0 | 3 | 0 | 1 | 0 | 0 |
| Atrial Fibrillation | 0 | | 1990 | 1991 | 33.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Atrial Septal Defect | 0 | | 1998 | 1998 | 26.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Atypical Ductal Hyperplasia | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Aura | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Auricular Fibrillation | 0 | | 1990 | 1991 | 33.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Autoimmune Diabetes | 0 | | 1983 | 2013 | 34.0 | low | 1 | 14 | 3 | 1 | 1 | 0 |
| Autoimmune Disease | 0 | | 1986 | 1996 | 34.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Autoimmune Diseases | 0 | | 1986 | 1996 | 34.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Autolysis, Dental Pulp | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Autonomic Failure, Progressive | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Autosomal Hemophilia A | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| B16 Melanoma | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bacteremia | 0 | | 1994 | 2001 | 26.8 | low | 0 | 0 | 3 | 1 | 0 | 0 |
| Bacterial Disease | 0 | | 1984 | 1991 | 36.0 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Bacterial Infections | 0 | | 1984 | 1991 | 36.0 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Bacterial Infections, Gram-Negative | 0 | | 2000 | 2001 | 23.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Bacterial Vaginitides | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bacteroides Infections | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Bancroftian Elephantiasis | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Basal Ganglia Hemorrhage | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Basedow Disease | 0 | | 1983 | 1987 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Basophilic Leukemia, Acute | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Behcet Syndrome | 0 | | 1984 | 1986 | 39.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Bends | 0 | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Benign Meningeal Neoplasms | 0 | | 1984 | 1993 | 34.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Benign Neoplasms | 0 | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Benign Neoplasms, Brain | 0 | | 1984 | 1998 | 32.6 | low | 0 | 1 | 4 | 0 | 0 | 0 |
| Benign Supratentorial Neoplasms | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Berger Disease | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Besnier-Boeck Disease | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Bilateral Headache | 0 | | 2007 | 2007 | 17.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Bile Duct Obstruction | 0 | | 1982 | 1996 | 33.8 | low | 0 | 2 | 4 | 0 | 0 | 0 |
| Bile Duct Obstruction, Extrahepatic | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bile Duct Obstruction, Intrahepatic | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Biliary Cirrhosis | 0 | | 1993 | 2007 | 26.3 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Biliary Tract Cancer | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Biliary Tract Neoplasms | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Birth Weight | 0 | | 1981 | 2005 | 27.0 | low | 0 | 1 | 3 | 1 | 0 | 0 |
| Bladder Diseases | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bleb | 0 | | 1981 | 1991 | 38.3 | low | 1 | 2 | 1 | 0 | 0 | 0 |
| Bleeding | 0 | | 1984 | 2011 | 33.5 | low | 1 | 8 | 5 | 0 | 1 | 0 |
| Bleeding Between Periods | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Blood Clot | 0 | | 1982 | 2022 | 26.4 | low | 4 | 21 | 28 | 15 | 9 | 2 |
| Blood Coagulation Disorders | 0 | | 1997 | 2021 | 15.2 | low | 0 | 0 | 2 | 0 | 2 | 1 |
| Blood Loss, Surgical | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Blood Platelet Disorders | 0 | | 1990 | 1993 | 32.5 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| Blood Poisoning | 0 | | 1984 | 2019 | 31.0 | low | 0 | 9 | 10 | 1 | 1 | 0 |
| Blood Pressure, High | 0 | | 1981 | 2017 | 32.0 | low | 31 | 94 | 84 | 24 | 5 | 0 |
| Blood Pressure, Low | 0 | | 1980 | 2017 | 30.4 | low | 4 | 12 | 5 | 5 | 3 | 0 |
| Blood Vessel Tumors | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Blunt Injuries | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Body Weight | 0 | | 1981 | 2016 | 30.3 | low | 7 | 29 | 33 | 15 | 1 | 0 |
| Bone Cancer | 0 | | 1985 | 1997 | 34.2 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| Bone Cysts | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Bone Fractures | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bone Loss, Osteoclastic | 0 | | 1980 | 1998 | 36.0 | low | 0 | 12 | 3 | 0 | 0 | 0 |
| Bone Neoplasms | 0 | | 1985 | 1997 | 34.2 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| Bordetella Infections | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bouillaud Disease | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bovine Diseases | 0 | | 1986 | 1994 | 34.3 | low | 0 | 4 | 2 | 0 | 0 | 0 |
| Bradyarrhythmia | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bradycardia | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Brain Concussion | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Brain Damage, Chronic | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Brain Diseases | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Brain Disorders | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Brain Edema | 0 | | 1985 | 2013 | 28.9 | low | 0 | 7 | 5 | 3 | 2 | 0 |
| Brain Embolism and Thrombosis | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Brain Hemorrhage, Cerebral | 0 | | 1985 | 2005 | 32.4 | low | 2 | 7 | 5 | 1 | 0 | 0 |
| Brain Inflammation | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Brain Injuries | 0 | | 1987 | 2013 | 25.7 | low | 1 | 3 | 1 | 0 | 2 | 0 |
| Brain Ischemia | 0 | | 1985 | 2008 | 32.6 | low | 2 | 16 | 16 | 3 | 0 | 0 |
| Brain Neoplasms | 0 | | 1984 | 1998 | 32.6 | low | 0 | 1 | 4 | 0 | 0 | 0 |
| Brain Swelling | 0 | | 1985 | 2013 | 28.9 | low | 0 | 7 | 5 | 3 | 2 | 0 |
| Brain Vascular Disorders | 0 | | 1986 | 1999 | 31.9 | low | 1 | 3 | 7 | 0 | 0 | 0 |
| Branch Retinal Artery Occlusion | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Branch Vein Occlusion | 0 | | 1993 | 1999 | 28.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Brazilian Spotted Fever | 0 | | 1990 | 2006 | 26.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Break-Bone Fever | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Breast Cancer | 0 | | 1983 | 2001 | 36.9 | low | 0 | 6 | 1 | 1 | 0 | 0 |
| Breast Diseases | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Breast Neoplasms | 0 | | 1983 | 2001 | 36.9 | low | 0 | 6 | 1 | 1 | 0 | 0 |
| Bright Disease | 0 | | 1982 | 2005 | 33.8 | low | 2 | 9 | 7 | 2 | 0 | 0 |
| Bronchial Hyperreactivity | 0 | | 1992 | 2002 | 27.7 | low | 2 | 0 | 6 | 1 | 0 | 0 |
| Bronchial Spasm | 0 | | 1988 | 1989 | 35.5 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| Bronchitis | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Bronchopulmonary Dysplasia | 0 | | 1986 | 1997 | 32.5 | low | 2 | 1 | 1 | 0 | 0 | 0 |
| Bronchospasm | 0 | | 1988 | 1989 | 35.5 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| Bronchospasm, Exercise-Induced | 0 | | 1989 | 1991 | 34.0 | low | 1 | 1 | 1 | 0 | 0 | 0 |
| Bruise | 0 | | 1992 | 1999 | 28.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Buerger Disease | 0 | | 1981 | 2014 | 28.2 | low | 0 | 3 | 1 | 0 | 2 | 0 |
| Burns | 0 | | 1981 | 2016 | 32.2 | low | 1 | 9 | 13 | 0 | 1 | 0 |
| Burns, Inhalation | 0 | | 1986 | 1993 | 35.2 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Cadaver | 0 | | 1984 | 2001 | 31.5 | low | 1 | 1 | 0 | 1 | 0 | 0 |
| Cadmium Poisoning | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Calcium Pyrophosphate Deposition Disease | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cancer of Colon | 0 | | 1986 | 2006 | 27.8 | low | 0 | 1 | 2 | 2 | 0 | 0 |
| Cancer of Digestive System | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cancer of Esophagus | 0 | | 2008 | 2008 | 16.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Cancer of Gallbladder | 0 | | 1984 | 1999 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Cancer of Gastrointestinal Tract | 0 | | 2019 | 2019 | 5.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Cancer of Head | 0 | | 1984 | 1988 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Cancer of Intestines | 0 | | 1993 | 2000 | 26.3 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| Cancer of Jaw | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cancer of Kidney | 0 | | 1986 | 2010 | 29.0 | low | 1 | 2 | 1 | 1 | 0 | 0 |
| Cancer of Larynx | 0 | | 1990 | 1993 | 32.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Cancer of Liver | 0 | | 1990 | 2006 | 27.1 | low | 1 | 0 | 4 | 3 | 0 | 0 |
| Cancer of Lung | 0 | | 1984 | 2004 | 30.0 | low | 1 | 4 | 4 | 3 | 0 | 0 |
| Cancer of Mouth | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cancer of Ovary | 0 | | 1983 | 2002 | 35.7 | low | 1 | 5 | 0 | 1 | 0 | 0 |
| Cancer of Pancreas | 0 | | 1984 | 2004 | 27.3 | low | 0 | 1 | 0 | 2 | 0 | 0 |
| Cancer of Pelvis | 0 | | 1986 | 1991 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Cancer of Pituitary | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cancer of Prostate | 0 | | 1981 | 2002 | 34.7 | low | 0 | 2 | 0 | 1 | 0 | 0 |
| Cancer of Skin | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cancer of Stomach | 0 | | 1998 | 2001 | 24.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Cancer of the Uterus | 0 | | 1984 | 1992 | 36.1 | low | 0 | 5 | 4 | 0 | 0 | 0 |
| Cancer, Embryonal | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Canine Diseases | 0 | | 1995 | 2010 | 21.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Capillary Leak Syndrome | 0 | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Carbon Tetrachloride Poisoning | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Carcinoma | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Carcinoma, Anaplastic | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Carcinoma, Embryonal | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Carcinoma, Epidermoid | 0 | | 1984 | 2008 | 32.4 | low | 2 | 4 | 3 | 1 | 0 | 0 |
| Carcinoma, Hepatocellular | 0 | | 1993 | 2002 | 28.0 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Carcinoma, Intraductal, Noninfiltrating | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Carcinoma, Non-Small Cell Lung | 0 | | 1993 | 2004 | 27.0 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Carcinoma, Non-Small-Cell Lung | 0 | | 1993 | 2004 | 27.0 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Carcinoma, Oat Cell | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Carcinoma, Renal Cell | 0 | | 1998 | 2010 | 20.0 | low | 1 | 0 | 1 | 1 | 0 | 0 |
| Carcinoma, Small Cell | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Carcinoma, Squamous Cell | 0 | | 1984 | 2008 | 32.4 | low | 2 | 4 | 3 | 1 | 0 | 0 |
| Carcinosarcoma | 0 | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Cardiac Complex, Premature | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Cardiac Death | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cardiac Diseases | 0 | | 1984 | 2010 | 30.5 | low | 0 | 3 | 6 | 2 | 0 | 0 |
| Cardiac Failure | 0 | | 1986 | 2008 | 31.8 | low | 3 | 5 | 4 | 1 | 0 | 0 |
| Cardiac Neurosis | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cardiac Rupture, Traumatic | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cardiac Septal Defect | 0 | | 2000 | 2000 | 24.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Cardiac Tamponade | 0 | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Cardiometabolic Syndrome | 0 | | 2006 | 2016 | 13.0 | low | 0 | 0 | 0 | 3 | 2 | 0 |
| Cardiomyopathies | 0 | | 1993 | 2001 | 27.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Cardiomyopathies, Primary | 0 | | 1993 | 2001 | 27.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Cardiomyopathy, Congestive | 0 | | 1991 | 2008 | 27.3 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Cardiomyopathy, Dilated | 0 | | 1991 | 2008 | 27.3 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Cardiomyopathy, Hypertrophic | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cardiomyopathy, Hypertrophic Obstructive | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cardiovascular Diseases | 0 | | 1990 | 2012 | 22.4 | low | 3 | 0 | 4 | 2 | 1 | 0 |
| Cardiovascular Pregnancy Complications | 0 | | 1981 | 2004 | 33.3 | low | 4 | 17 | 17 | 2 | 0 | 0 |
| Cardiovascular Stroke | 0 | | 1981 | 2018 | 29.4 | low | 6 | 26 | 31 | 13 | 4 | 0 |
| Caries, Dental | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Carotid Arteriopathies, Traumatic | 0 | | 1999 | 2001 | 24.3 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Carotid Artery Diseases | 0 | | 1984 | 2009 | 29.8 | low | 0 | 3 | 0 | 2 | 0 | 0 |
| Carotid Artery Narrowing | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Carotid Artery Thrombosis | 0 | | 1982 | 2022 | 18.8 | low | 1 | 1 | 2 | 2 | 4 | 1 |
| Carotid Stenosis | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Cataract | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cataract, Membranous | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| CBS Deficiency | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Celiac Disease | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Celiac Sprue | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cell Transformation, Neoplastic | 0 | | 1987 | 2008 | 27.7 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Cells, Neoplasm Circulating | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Central Hypothyroidism | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Centriacinar Emphysema | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Cerebral Arteriosclerosis | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cerebral Concussion | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cerebral Hemorrhage | 0 | | 1985 | 2005 | 32.4 | low | 2 | 7 | 5 | 1 | 0 | 0 |
| Cerebral Hemorrhage, Hypertensive | 0 | | 2007 | 2008 | 16.5 | low | 0 | 0 | 0 | 2 | 0 | 0 |
| Cerebral Infarction | 0 | | 1988 | 2015 | 26.2 | low | 2 | 2 | 8 | 0 | 3 | 0 |
| Cerebral Infarction, Middle Cerebral Artery | 0 | | 2011 | 2015 | 10.7 | low | 0 | 0 | 0 | 0 | 3 | 0 |
| Cerebral Ischemia | 0 | | 1985 | 2008 | 32.6 | low | 2 | 16 | 16 | 3 | 0 | 0 |
| Cerebro-Hepato-Renal Syndrome | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cerebrovascular Disorders | 0 | | 1986 | 1999 | 31.9 | low | 1 | 3 | 7 | 0 | 0 | 0 |
| Chemical and Drug Induced Liver Injury | 0 | | 1990 | 2010 | 27.2 | low | 0 | 0 | 4 | 1 | 0 | 0 |
| Chemical Dependence | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cholangitis | 0 | | 1990 | 2000 | 29.0 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| Cholecystitis | 0 | | 1990 | 1999 | 30.8 | low | 0 | 0 | 9 | 0 | 0 | 0 |
| Cholelithiasis | 0 | | 1990 | 1992 | 33.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Cholera Infantum | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cholestasis | 0 | | 1982 | 1996 | 33.8 | low | 0 | 2 | 4 | 0 | 0 | 0 |
| Cholestasis, Intrahepatic | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cholesteatoma | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Chondroblastoma | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Chondrocalcinosis | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Chondrodysplasia Punctata | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Choriocarcinoma | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Chronic Disease | 0 | | 1980 | 2010 | 31.5 | low | 4 | 15 | 16 | 6 | 0 | 0 |
| Chronic Illness | 0 | | 1980 | 2010 | 31.5 | low | 4 | 15 | 16 | 6 | 0 | 0 |
| Chronic Kidney Failure | 0 | | 1981 | 2007 | 35.0 | low | 2 | 17 | 6 | 4 | 0 | 0 |
| Chronic Lung Injury | 0 | | 1985 | 1999 | 33.9 | low | 0 | 4 | 3 | 0 | 0 | 0 |
| Circulatory Collapse | 0 | | 1983 | 2003 | 32.5 | low | 1 | 4 | 7 | 1 | 0 | 0 |
| Cirrhoses, Experimental Liver | 0 | | 1988 | 2014 | 23.0 | low | 0 | 1 | 1 | 1 | 1 | 0 |
| Cirrhosis | 0 | | 1990 | 2015 | 21.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Cirrhosis, Liver | 0 | | 1986 | 2016 | 31.1 | low | 1 | 8 | 9 | 3 | 1 | 0 |
| Claustrophobia | 0 | | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| Cleft Palate | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cleft Palate, Isolated | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Closed Head Injuries | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Coagulation Disorders, Blood | 0 | | 1997 | 2021 | 15.2 | low | 0 | 0 | 2 | 0 | 2 | 1 |
| Coagulation, Disseminated Intravascular | 0 | | 1981 | 1990 | 37.6 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| Coarctation of Aorta | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Cold Fingers, Hereditary | 0 | | 1981 | 2018 | 33.6 | low | 2 | 9 | 2 | 0 | 1 | 0 |
| Colicky Pain | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Colitis | 0 | | 1988 | 2016 | 25.7 | low | 0 | 2 | 3 | 0 | 2 | 0 |
| Colitis Gravis | 0 | | 1982 | 1995 | 35.7 | low | 0 | 3 | 3 | 0 | 0 | 0 |
| Colitis, Granulomatous | 0 | | 1982 | 1986 | 40.0 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| Colitis, Ulcerative | 0 | | 1982 | 1995 | 35.7 | low | 0 | 3 | 3 | 0 | 0 | 0 |
| Colonic Inertia | 0 | | 2007 | 2007 | 17.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Colonic Neoplasms | 0 | | 1986 | 2006 | 27.8 | low | 0 | 1 | 2 | 2 | 0 | 0 |
| Colorectal Cancer | 0 | | 2008 | 2017 | 11.5 | low | 1 | 0 | 0 | 1 | 1 | 0 |
| Colorectal Neoplasms | 0 | | 2008 | 2017 | 11.5 | low | 1 | 0 | 0 | 1 | 1 | 0 |
| Compensatory Hyperinsulinemia | 0 | | 1989 | 1996 | 31.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Complication, Intraoperative | 0 | | 1989 | 2017 | 18.5 | low | 3 | 1 | 0 | 2 | 1 | 0 |
| Complication, Postoperative | 0 | | 1986 | 2019 | 24.6 | low | 3 | 4 | 3 | 3 | 3 | 0 |
| Complications of Diabetes Mellitus | 0 | | 1994 | 2014 | 18.3 | low | 0 | 0 | 1 | 1 | 1 | 0 |
| Complications, Hematologic Pregnancy | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Complications, Infectious Pregnancy | 0 | | 1989 | 1996 | 31.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Complications, Labor | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Complications, Pregnancy | 0 | | 1981 | 1992 | 39.3 | low | 0 | 8 | 1 | 0 | 0 | 0 |
| Congenital Thrombotic Thrombocytopenic Purpura | 0 | | 1981 | 1986 | 41.0 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| Congenital Zika Syndrome | 0 | | 2020 | 2020 | 4.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Conjunctivitis, Allergic | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Constipation | 0 | | 2007 | 2007 | 17.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Constriction, Pathologic | 0 | | 1985 | 2011 | 28.8 | low | 0 | 1 | 2 | 0 | 1 | 0 |
| Constriction, Pathological | 0 | | 1985 | 2011 | 28.8 | low | 0 | 1 | 2 | 0 | 1 | 0 |
| Contusions | 0 | | 1992 | 1999 | 28.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Conus Medullaris Syndrome | 0 | | 1988 | 2004 | 30.0 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Convalescence | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Cor Pulmonale | 0 | | 1987 | 2010 | 27.1 | low | 0 | 1 | 6 | 2 | 0 | 0 |
| Coronary Artery Disease | 0 | | 1987 | 2012 | 23.9 | low | 1 | 1 | 3 | 4 | 2 | 0 |
| Coronary Artery Vasospasm | 0 | | 1985 | 2004 | 31.0 | low | 0 | 4 | 3 | 2 | 0 | 0 |
| Coronary Disease | 0 | | 1981 | 2007 | 35.8 | low | 10 | 72 | 38 | 2 | 0 | 0 |
| Coronary Heart Disease | 0 | | 1981 | 2007 | 35.8 | low | 10 | 72 | 38 | 2 | 0 | 0 |
| Coronary Restenosis | 0 | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Coronary Thrombosis | 0 | | 1986 | 2011 | 31.4 | low | 0 | 3 | 4 | 0 | 1 | 0 |
| Coronary Vasospasm | 0 | | 1985 | 2004 | 31.0 | low | 0 | 4 | 3 | 2 | 0 | 0 |
| Cough | 0 | | 1997 | 1997 | 27.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Craniocerebral Injuries | 0 | | 1981 | 1987 | 39.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Craniocerebral Trauma | 0 | | 1981 | 1987 | 39.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Critical Illness | 0 | | 1992 | 2015 | 20.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Crohn Disease | 0 | | 1982 | 1986 | 40.0 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| Cruveilhier-Baumgarten Syndrome | 0 | | 1985 | 2007 | 28.6 | low | 0 | 3 | 10 | 4 | 0 | 0 |
| Cryptogenic Fibrosing Alveolitis | 0 | | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Curling Ulcer | 0 | | 1983 | 1993 | 37.1 | low | 1 | 6 | 1 | 0 | 0 | 0 |
| Cyst | 0 | | 1992 | 2001 | 27.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Cyst, Dental Root | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cystadenocarcinoma | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Cystic Echinococcosis | 0 | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Cystic Fibrosis | 0 | | 1986 | 1986 | 38.0 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| Cystic Fibrosis of Pancreas | 0 | | 1986 | 1986 | 38.0 | low | 1 | 2 | 0 | 0 | 0 | 0 |
| Cytomegalic Inclusion Disease | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Cytomegalovirus Infections | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| DDD MPGNII | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Deafness, Sudden | 0 | | 1997 | 1997 | 27.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Death, Sudden | 0 | | 1982 | 2003 | 36.2 | low | 0 | 5 | 0 | 1 | 0 | 0 |
| Decerebrate Posturing | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Deep Vein Thrombosis | 0 | | 2001 | 2020 | 13.1 | low | 1 | 0 | 0 | 2 | 5 | 0 |
| Deficiency Diseases | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Deficiency, Magnesium | 0 | | 1986 | 2008 | 26.7 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Deficiency, Vitamin D | 0 | | 2019 | 2019 | 5.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Deficiency, Vitamin E | 0 | | 1981 | 1995 | 37.4 | low | 0 | 5 | 3 | 0 | 0 | 0 |
| Deficiency, Yang | 0 | | 1992 | 1993 | 31.5 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| Deficiency, Yin | 0 | | 1992 | 1997 | 29.8 | low | 2 | 0 | 4 | 0 | 0 | 0 |
| Delayed Hypersensitivity | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Delayed Postpartum Hemorrhage | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Dengue | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Dental Caries | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Dental Pulp Exposure | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Dental Tissue Neoplasms | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Dentigerous Cyst | 0 | | 1985 | 1989 | 37.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Dermatitis, Atopic | 0 | | 1987 | 2004 | 31.6 | low | 1 | 2 | 2 | 1 | 0 | 0 |
| Dermatitis, Contact, Phototoxic | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Dermatoses | 0 | | 1983 | 1989 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Diabetes Insipidus | 0 | | 1983 | 1994 | 37.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Diabetes Mellitus | 0 | | 1980 | 1999 | 37.4 | low | 0 | 17 | 3 | 0 | 0 | 0 |
| Diabetes Mellitus, Adult-Onset | 0 | | 1984 | 2015 | 27.0 | low | 4 | 9 | 20 | 9 | 4 | 0 |
| Diabetes Mellitus, Gestational | 0 | | 1998 | 2002 | 24.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Diabetes Mellitus, Type 1 | 0 | | 1983 | 2013 | 34.0 | low | 1 | 14 | 3 | 1 | 1 | 0 |
| Diabetes Mellitus, Type 2 | 0 | | 1984 | 2015 | 27.0 | low | 4 | 9 | 20 | 9 | 4 | 0 |
| Diabetes, Gestational | 0 | | 1998 | 2002 | 24.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Diabetic Angiopathies | 0 | | 1981 | 2007 | 32.9 | low | 0 | 6 | 3 | 2 | 0 | 0 |
| Diabetic Glomerulosclerosis | 0 | | 1987 | 2003 | 28.4 | low | 4 | 2 | 6 | 4 | 0 | 0 |
| Diabetic Ketoacidosis | 0 | | 1982 | 1996 | 36.4 | low | 1 | 6 | 3 | 0 | 0 | 0 |
| Diabetic Nephropathies | 0 | | 1987 | 2003 | 28.4 | low | 4 | 2 | 6 | 4 | 0 | 0 |
| Diabetic Neuropathies | 0 | | 1987 | 2001 | 30.6 | low | 0 | 2 | 4 | 1 | 0 | 0 |
| Diabetic Retinopathy | 0 | | 1981 | 2003 | 34.7 | low | 0 | 5 | 4 | 1 | 0 | 0 |
| Diaphragmatic Hernia | 0 | | 1984 | 1992 | 36.2 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| Diarrhea | 0 | | 1993 | 2007 | 24.0 | low | 1 | 0 | 1 | 1 | 0 | 0 |
| Diathesis | 0 | | 1988 | 2000 | 32.0 | low | 1 | 2 | 2 | 0 | 0 | 0 |
| Diffuse Mixed Small and Large Cell Lymphoma | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Diffuse Parenchymal Lung Disease | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Digestive System Diseases | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Digestive System Disorders | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Digestive System Neoplasms | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Dilatation, Pathologic | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Disc, Herniated | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Disease | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Disease Exacerbation | 0 | | 1999 | 2016 | 15.7 | low | 0 | 0 | 1 | 4 | 2 | 0 |
| Disease Models, Animal | 0 | | 1981 | 2021 | 25.2 | low | 0 | 41 | 53 | 40 | 27 | 1 |
| Disease, Pulmonary | 0 | | 1981 | 2008 | 32.9 | low | 1 | 17 | 16 | 4 | 0 | 0 |
| Diseases in Twins | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Diseases, Occupational | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Disseminated Intravascular Coagulation | 0 | | 1981 | 1990 | 37.6 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| Distorted Hearing | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Dizziness | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Dizzyness | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Down Syndrome | 0 | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Drowning | 0 | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Drug Withdrawal Symptoms | 0 | | 1987 | 1996 | 34.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Ductus Arteriosus, Patent | 0 | | 1984 | 2008 | 34.4 | low | 3 | 11 | 1 | 2 | 0 | 0 |
| Duodenal Diseases | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Duodenal Ulcer | 0 | | 1983 | 1993 | 37.1 | low | 1 | 6 | 1 | 0 | 0 | 0 |
| Dysentery, Bacillary | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Dysentery, Shiga bacillus | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Dyslipidemia | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Dyslipidemias | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Dysmenorrhea | 0 | | 1983 | 2011 | 26.0 | low | 3 | 1 | 3 | 2 | 1 | 0 |
| E coli Infections | 0 | | 1984 | 2013 | 31.3 | low | 0 | 7 | 10 | 2 | 1 | 0 |
| Eclampsia | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Eczema, Atopic | 0 | | 1987 | 2004 | 31.6 | low | 1 | 2 | 2 | 1 | 0 | 0 |
| Edema | 0 | | 1981 | 2006 | 32.7 | low | 0 | 7 | 7 | 1 | 0 | 0 |
| Edema-Proteinuria-Hypertension Gestosis | 0 | | 1981 | 2015 | 31.3 | low | 6 | 29 | 46 | 7 | 1 | 0 |
| Edema, Pulmonary | 0 | | 1982 | 2004 | 34.1 | low | 0 | 17 | 15 | 2 | 0 | 0 |
| EHS Tumor | 0 | | 1984 | 1993 | 35.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Electrolytes | 0 | | 1983 | 2007 | 32.7 | low | 3 | 9 | 7 | 2 | 0 | 0 |
| Elephantiasis, Filarial | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Elevated Cholesterol | 0 | | 1982 | 2009 | 30.7 | low | 0 | 4 | 9 | 1 | 0 | 0 |
| Embolism, Fat | 0 | | 1990 | 1997 | 31.5 | low | 0 | 0 | 4 | 0 | 0 | 0 |
| Embolism, Pulmonary | 0 | | 1981 | 2014 | 33.6 | low | 0 | 14 | 3 | 4 | 1 | 0 |
| Embryopathies | 0 | | 1989 | 1991 | 34.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Emesis | 0 | | 1982 | 1987 | 38.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Empyema, Gall Bladder | 0 | | 1990 | 1999 | 30.8 | low | 0 | 0 | 9 | 0 | 0 | 0 |
| Encephalitis | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Encephalitis, Polio | 0 | | 2011 | 2011 | 13.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Encephalopathy, Hepatic | 0 | | 2006 | 2016 | 13.0 | low | 0 | 0 | 0 | 1 | 1 | 0 |
| Endometrial Diseases | 0 | | 1996 | 2001 | 25.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Endometrioma | 0 | | 1981 | 2015 | 32.5 | low | 4 | 12 | 7 | 1 | 2 | 0 |
| Endometriosis | 0 | | 1981 | 2015 | 32.5 | low | 4 | 12 | 7 | 1 | 2 | 0 |
| Endometritis | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Endomyometritis | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Endotoxemia | 0 | | 1996 | 2007 | 25.0 | low | 0 | 0 | 9 | 4 | 0 | 0 |
| Endotoxin Shock | 0 | | 1980 | 2008 | 35.2 | low | 0 | 48 | 25 | 3 | 0 | 0 |
| Enterocolitis, Pseudomembranous | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Eosinophilia | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Eosinophilia, Tropical | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Eosinophilic Granuloma | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Epilepsy | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Equine Diseases | 0 | | 1982 | 1999 | 34.2 | low | 1 | 8 | 5 | 0 | 0 | 0 |
| Erectile Dysfunction | 0 | | 1992 | 1994 | 31.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Erythema | 0 | | 1983 | 1983 | 41.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Erythremia | 0 | | 1985 | 1991 | 36.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Escherichia coli Infections | 0 | | 1984 | 2013 | 31.3 | low | 0 | 7 | 10 | 2 | 1 | 0 |
| Esophageal and Gastric Varices | 0 | | 1986 | 1989 | 36.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Esophageal Neoplasms | 0 | | 2008 | 2008 | 16.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Esophageal Varices | 0 | | 1986 | 1989 | 36.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Ewing Sarcoma | 0 | | 1985 | 1986 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Experimental Hepatoma | 0 | | 1988 | 2006 | 25.0 | low | 0 | 1 | 0 | 2 | 0 | 0 |
| Experimental Leukemia | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Experimental Lung Inflammation | 0 | | 1985 | 2009 | 31.6 | low | 0 | 3 | 2 | 2 | 0 | 0 |
| Experimental Mammary Neoplasms | 0 | | 1983 | 1988 | 38.0 | low | 0 | 5 | 0 | 0 | 0 | 0 |
| Experimental Radiation Injuries | 0 | | 1984 | 1996 | 33.0 | low | 0 | 3 | 3 | 0 | 0 | 0 |
| Exposure, Dental Pulp | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Extramembranous Glomerulopathy | 0 | | 1998 | 1999 | 25.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Extravascular Hemolysis | 0 | | 1985 | 2002 | 30.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| Eye Diseases | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Eye Disorders | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Eye Injuries, Penetrating | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Facial Neoplasms | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Fallot's Tetralogy | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Familial Primary Pulmonary Hypertension | 0 | | 2011 | 2011 | 13.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Fasting Hypoglycemia | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Fatty Liver | 0 | | 2004 | 2011 | 16.5 | low | 0 | 0 | 0 | 1 | 1 | 0 |
| Female Genital Diseases | 0 | | 1985 | 1990 | 36.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Female Genital Neoplasms | 0 | | 1982 | 1990 | 38.0 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Fetal Death | 0 | | 1981 | 1992 | 39.4 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| Fetal Distress | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Fetal Growth Restriction | 0 | | 1981 | 2011 | 29.3 | low | 1 | 2 | 8 | 1 | 1 | 0 |
| Fetal Growth Retardation | 0 | | 1981 | 2011 | 29.3 | low | 1 | 2 | 8 | 1 | 1 | 0 |
| Fetal Hypoxia | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Fever | 0 | | 1985 | 2016 | 26.7 | low | 1 | 1 | 1 | 0 | 1 | 0 |
| Fibroid | 0 | | 1985 | 1992 | 35.5 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| Fibromuscular Dysplasia | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Fibrosarcoma | 0 | | 1987 | 1988 | 36.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Fibrosis | 0 | | 1990 | 2015 | 21.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Fistula | 0 | | 1981 | 1986 | 40.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Flaccid Quadriplegia | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Flushing | 0 | | 1984 | 2019 | 23.8 | low | 5 | 3 | 1 | 2 | 2 | 0 |
| Focal Segmental Glomerulosclerosis | 0 | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Foot Diseases | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Foreign-Body Granuloma | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Foreign-Body Reaction | 0 | | 1986 | 1990 | 36.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Fractures, Bone | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Frostbite | 0 | | 1997 | 1998 | 26.3 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| Gallbladder Neoplasms | 0 | | 1984 | 1999 | 32.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Gallstone Disease | 0 | | 1990 | 1992 | 33.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Gasser Syndrome | 0 | | 1981 | 2002 | 35.8 | low | 0 | 6 | 2 | 1 | 0 | 0 |
| Gastric Diseases | 0 | | 1985 | 2012 | 24.7 | low | 0 | 3 | 4 | 5 | 1 | 0 |
| Gastric Fistula | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Gastric Ulcer | 0 | | 1983 | 2015 | 29.3 | low | 0 | 14 | 9 | 7 | 3 | 0 |
| Gastritis | 0 | | 1989 | 2015 | 28.7 | low | 0 | 2 | 3 | 0 | 1 | 0 |
| Gastroduodenal Ulcer | 0 | | 1985 | 2016 | 32.3 | low | 0 | 5 | 4 | 0 | 1 | 0 |
| Gastroenteritis | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Gastrointestinal Hemorrhage | 0 | | 1984 | 1994 | 36.0 | low | 1 | 3 | 1 | 0 | 0 | 0 |
| Genetic Predisposition | 0 | | 2011 | 2011 | 13.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Genital Diseases, Female | 0 | | 1985 | 1990 | 36.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Genital Neoplasms, Female | 0 | | 1982 | 1990 | 38.0 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Genito-urinary Cancer | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Germinoblastoma | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Gestational Hypertension | 0 | | 2004 | 2004 | 20.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Giant Osteoid Osteoma | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Gingival Hyperplasia | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Gingivitis | 0 | | 1985 | 1992 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Glial Cell Tumors | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Glioblastoma | 0 | | 1984 | 1998 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Glioma | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Glomerulonephritis | 0 | | 1982 | 2005 | 33.8 | low | 2 | 9 | 7 | 2 | 0 | 0 |
| Glomerulonephritis, IGA | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Glomerulonephritis, Lupus | 0 | | 1987 | 2001 | 28.7 | low | 1 | 1 | 4 | 1 | 0 | 0 |
| Glomerulonephritis, Membranoproliferative | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Glomerulonephritis, Membranous | 0 | | 1998 | 1999 | 25.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Glomerulonephritis, Minimal Change | 0 | | 1986 | 2000 | 32.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Glomerulosclerosis, Focal Segmental | 0 | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Glucose Intolerance | 0 | | 1998 | 2012 | 20.5 | low | 1 | 0 | 1 | 2 | 1 | 0 |
| Glycosuria | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Goldblatt Syndrome | 0 | | 1984 | 2005 | 35.9 | low | 0 | 12 | 1 | 1 | 0 | 0 |
| Graft Occlusion, Vascular | 0 | | 1985 | 1997 | 33.7 | low | 0 | 5 | 4 | 0 | 0 | 0 |
| Graft vs Host Disease | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Graft-Versus-Host Disease | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Gram-Negative Bacterial Infections | 0 | | 2000 | 2001 | 23.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Granulocytic Leukemia | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Granulocytic Leukemia, Chronic | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Granuloma | 0 | | 1979 | 1985 | 43.0 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| Granuloma, Hodgkin | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Granulomas | 0 | | 1979 | 1985 | 43.0 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| Graves Disease | 0 | | 1983 | 1987 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Group A Strep Infection | 0 | | 1984 | 1993 | 36.0 | low | 0 | 6 | 3 | 0 | 0 | 0 |
| Hay Fever | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| HbS Disease | 0 | | 1982 | 2017 | 31.1 | low | 0 | 5 | 4 | 1 | 1 | 0 |
| Head and Neck Neoplasms | 0 | | 1984 | 1988 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Headache | 0 | | 2007 | 2007 | 17.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Heart Arrest | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Heart Defects, Congenital | 0 | | 1987 | 2010 | 28.2 | low | 0 | 1 | 2 | 1 | 0 | 0 |
| Heart Disease, Ischemic | 0 | | 1992 | 2016 | 24.7 | low | 4 | 0 | 19 | 7 | 1 | 0 |
| Heart Diseases | 0 | | 1984 | 2010 | 30.5 | low | 0 | 3 | 6 | 2 | 0 | 0 |
| Heart Failure | 0 | | 1986 | 2008 | 31.8 | low | 3 | 5 | 4 | 1 | 0 | 0 |
| Heart Septal Defects, Ventricular | 0 | | 1998 | 1998 | 26.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Heart Valve Diseases | 0 | | 2010 | 2010 | 14.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Heavy Menstrual Bleeding | 0 | | 1981 | 1992 | 37.5 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Helicobacter Infections | 0 | | 1993 | 2003 | 26.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| HELLP Syndrome | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hematochezia | 0 | | 1984 | 1994 | 36.0 | low | 1 | 3 | 1 | 0 | 0 | 0 |
| Hematoma | 0 | | 1984 | 1987 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Hemolysis | 0 | | 1985 | 2002 | 30.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| Hemolysis, Elevated Liver Enzymes, Lowered Platelets | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hemolytic-Uremic Syndrome | 0 | | 1981 | 2002 | 35.8 | low | 0 | 6 | 2 | 1 | 0 | 0 |
| Hemophilia A | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hemorrhage | 0 | | 1984 | 2011 | 33.5 | low | 1 | 8 | 5 | 0 | 1 | 0 |
| Hemorrhage, Oral | 0 | | 1987 | 1987 | 37.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| Hemorrhage, Subarachnoid | 0 | | 1983 | 2012 | 34.9 | low | 1 | 16 | 6 | 0 | 1 | 0 |
| Hemorrhage, Uterine | 0 | | 2020 | 2020 | 4.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Hemorrhagic Diathesis | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hemorrhagic Disorders | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hemorrhagic Fever with Renal Syndrome | 0 | | 1990 | 1992 | 33.0 | low | 0 | 0 | 4 | 0 | 0 | 0 |
| Hemorrhagic Fever, Epidemic | 0 | | 1990 | 1992 | 33.0 | low | 0 | 0 | 4 | 0 | 0 | 0 |
| Hemorrhagic Shock | 0 | | 1985 | 1997 | 32.4 | low | 0 | 2 | 10 | 0 | 0 | 0 |
| Hemorrhagic Thrombocythemia | 0 | | 1991 | 2014 | 19.0 | low | 1 | 0 | 1 | 1 | 1 | 0 |
| Hepatic Encephalopathy | 0 | | 2006 | 2016 | 13.0 | low | 0 | 0 | 0 | 1 | 1 | 0 |
| Hepatic Failure | 0 | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Hepatic Veno Occlusive Disease | 0 | | 1996 | 1998 | 27.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Hepatic Veno-Occlusive Disease | 0 | | 1996 | 1998 | 27.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Hepatitis B | 0 | | 1990 | 1997 | 30.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Hepatitis B Virus Infection | 0 | | 1990 | 1997 | 30.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Hepatitis, Alcoholic | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hepatitis, Viral, Human | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hepato-Pulmonary Syndrome | 0 | | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Hepatocellular Carcinoma | 0 | | 1993 | 2002 | 28.0 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Hepatopulmonary Syndrome | 0 | | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Heritable Pulmonary Arterial Hypertension | 0 | | 2011 | 2011 | 13.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Hernias, Diaphragmatic, Congenital | 0 | | 1984 | 1992 | 36.2 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| Herpes Simplex | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Herpes Simplex Virus Infection | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hibernation, Myocardial | 0 | | 1996 | 2002 | 25.2 | low | 0 | 0 | 3 | 1 | 0 | 0 |
| HIV Coinfection | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| HIV Infections | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hives | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hodgkin Disease | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Homocystinuria | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hyaline Membrane Disease | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hydatid Mole | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hydatidiform Mole | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hydronephrosis | 0 | | 1981 | 1997 | 35.2 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| Hyperaldosteronism | 0 | | 1980 | 1986 | 41.8 | low | 0 | 8 | 0 | 0 | 0 | 0 |
| Hyperammonemia | 0 | | 2015 | 2015 | 9.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Hypercapnia | 0 | | 1984 | 2009 | 28.8 | low | 0 | 3 | 6 | 4 | 0 | 0 |
| Hypercholesterolemia | 0 | | 1982 | 2009 | 30.7 | low | 0 | 4 | 9 | 1 | 0 | 0 |
| Hyperchylomicronemia Late Onset | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypercoagulability | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Hyperemia | 0 | | 1981 | 2013 | 31.2 | low | 0 | 4 | 5 | 1 | 1 | 0 |
| Hyperesthesia | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hyperglycemia | 0 | | 1997 | 2000 | 25.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Hyperglycemia, Postprandial | 0 | | 1997 | 2000 | 25.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Hyperinsulinism | 0 | | 1989 | 1996 | 31.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Hyperkalemia | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hyperlipemia | 0 | | 1986 | 2017 | 27.3 | low | 0 | 4 | 10 | 3 | 2 | 0 |
| Hyperlipidemias | 0 | | 1986 | 2017 | 27.3 | low | 0 | 4 | 10 | 3 | 2 | 0 |
| Hyperlipoproteinemia | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hyperlipoproteinemia Type II | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hyperlipoproteinemias | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hyperoxia | 0 | | 1998 | 2002 | 24.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Hyperplasia | 0 | | 1991 | 2000 | 28.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Hyperpotassemia | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypersensitivity | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hypersensitivity, Type III | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Hypertension | 0 | | 1981 | 2017 | 32.0 | low | 31 | 94 | 84 | 24 | 5 | 0 |
| Hypertension, Portal | 0 | | 1985 | 2007 | 28.6 | low | 0 | 3 | 10 | 4 | 0 | 0 |
| Hypertension, Pregnancy-Induced | 0 | | 2004 | 2004 | 20.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Hypertension, Pulmonary | 0 | | 1982 | 2021 | 30.0 | low | 2 | 29 | 30 | 13 | 3 | 1 |
| Hypertension, Renal | 0 | | 1985 | 2015 | 25.6 | low | 0 | 3 | 1 | 3 | 1 | 0 |
| Hypertension, Renovascular | 0 | | 1984 | 2005 | 35.9 | low | 0 | 12 | 1 | 1 | 0 | 0 |
| Hyperthyroid | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hyperthyroidism | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypertriglyceridemia | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypertrophy | 0 | | 1986 | 2015 | 21.3 | low | 0 | 1 | 0 | 1 | 1 | 0 |
| Hypertrophy, Left Ventricular | 0 | | 1993 | 1994 | 30.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Hypertrophy, Right Ventricular | 0 | | 2004 | 2016 | 15.5 | low | 0 | 0 | 0 | 3 | 1 | 0 |
| Hyperuricemia | 0 | | 2008 | 2008 | 16.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Hyperventilation | 0 | | 1981 | 2003 | 34.7 | low | 0 | 3 | 2 | 1 | 0 | 0 |
| Hypoglycemia | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypokalemia | 0 | | 1982 | 2004 | 33.2 | low | 1 | 2 | 1 | 1 | 0 | 0 |
| Hypomenorrhea | 0 | | 1987 | 2007 | 27.0 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| Hypotension | 0 | | 1980 | 2017 | 30.4 | low | 4 | 12 | 5 | 5 | 3 | 0 |
| Hypotension, Orthostatic | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypotension, Postural | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypothermia | 0 | | 1994 | 2002 | 26.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Hypothermia, Accidental | 0 | | 1994 | 2002 | 26.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Hypothyroidism | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Hypoxia | 0 | | 1981 | 2009 | 32.0 | low | 0 | 30 | 24 | 10 | 0 | 0 |
| Hypoxia-Ischemia, Brain | 0 | | 2003 | 2003 | 21.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Icterus | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Icterus Gravis Neonatorum | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Idiopathic Inflammatory Myopathies | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Idiopathic Pulmonary Fibrosis | 0 | | 2014 | 2014 | 10.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Impaired Glucose Tolerance | 0 | | 1998 | 2012 | 20.5 | low | 1 | 0 | 1 | 2 | 1 | 0 |
| Impotence | 0 | | 1992 | 1994 | 31.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Inadequate Sleep | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Infant, Premature, Diseases | 0 | | 1983 | 1990 | 37.8 | low | 3 | 8 | 1 | 0 | 0 | 0 |
| Infant, Small for Gestational Age | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Infantile Respiratory Distress Syndrome | 0 | | 1982 | 2002 | 35.5 | low | 2 | 13 | 3 | 1 | 0 | 0 |
| Infarct | 0 | | 1999 | 2002 | 23.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Infarction, Middle Cerebral Artery | 0 | | 2011 | 2015 | 10.7 | low | 0 | 0 | 0 | 0 | 3 | 0 |
| Infection | 0 | | 1989 | 1996 | 32.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Infection, Postoperative Wound | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Infection, Wound | 0 | | 1984 | 1986 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Infections | 0 | | 1989 | 1996 | 32.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Infections, Helicobacter | 0 | | 1993 | 2003 | 26.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Infections, Listeria | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Infections, Paramyxoviridae | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Infections, Pasteurella | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Infections, Plasmodium | 0 | | 1984 | 1986 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Infections, Pneumococcal | 0 | | 1991 | 1998 | 29.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Infections, Pseudomonas | 0 | | 1985 | 1990 | 37.1 | low | 0 | 6 | 1 | 0 | 0 | 0 |
| Infections, Respiratory Syncytial Virus | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Infections, Respirovirus | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Infections, Yersinia | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Infertility | 0 | | 1984 | 1996 | 34.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Infertility, Female | 0 | | 1981 | 2001 | 36.1 | low | 0 | 5 | 1 | 1 | 0 | 0 |
| Infertility, Male | 0 | | 1979 | 1979 | 45.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Inflammation | 0 | | 1979 | 2017 | 28.3 | low | 2 | 16 | 17 | 15 | 3 | 0 |
| Inflammation, Endodontic | 0 | | 1987 | 1999 | 31.2 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| Inflammatory Response Syndrome, Systemic | 0 | | 1996 | 2001 | 25.7 | low | 1 | 0 | 2 | 1 | 0 | 0 |
| Inhalation Injury, Smoke | 0 | | 1993 | 2005 | 25.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Injuries | 0 | | 1986 | 1996 | 34.8 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| Injuries, Multiple | 0 | | 1991 | 2021 | 18.0 | low | 0 | 0 | 1 | 0 | 0 | 1 |
| Injuries, Spinal | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Injuries, Spinal Cord | 0 | | 1985 | 2007 | 30.4 | low | 0 | 5 | 5 | 3 | 0 | 0 |
| Injury, Ischemia-Reperfusion | 0 | | 1988 | 2016 | 25.5 | low | 1 | 1 | 35 | 17 | 4 | 0 |
| Injury, Myocardial Reperfusion | 0 | | 1989 | 2015 | 25.4 | low | 2 | 2 | 25 | 10 | 2 | 0 |
| Innate Inflammatory Response | 0 | | 1979 | 2017 | 28.3 | low | 2 | 16 | 17 | 15 | 3 | 0 |
| Insulin Resistance | 0 | | 2002 | 2015 | 16.0 | low | 0 | 0 | 0 | 3 | 1 | 0 |
| Insulin Sensitivity | 0 | | 2002 | 2015 | 16.0 | low | 0 | 0 | 0 | 3 | 1 | 0 |
| Insulinoma | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Intermittent Claudication | 0 | | 1988 | 1997 | 30.3 | low | 1 | 1 | 2 | 0 | 0 | 0 |
| Interstitial Nephritis | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Intervertebral Disc Displacement | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Intestinal Diseases | 0 | | 1988 | 2014 | 25.0 | low | 0 | 1 | 1 | 0 | 1 | 0 |
| Intestinal Neoplasms | 0 | | 1993 | 2000 | 26.3 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| Intestinal Perforation | 0 | | 1995 | 1995 | 29.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Intracranial Aneurysm | 0 | | 1985 | 1994 | 36.1 | low | 0 | 7 | 2 | 0 | 0 | 0 |
| Intracranial Arteriosclerosis | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Intradural-Extramedullary Spinal Cord Neoplasms | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Intraocular Pressure | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Intraventricular Septal Defects | 0 | | 1998 | 1998 | 26.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Invasiveness, Neoplasm | 0 | | 1991 | 2002 | 27.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Ischemia | 0 | | 1981 | 2007 | 31.3 | low | 2 | 17 | 27 | 9 | 0 | 0 |
| Ischemic Attack, Transient | 0 | | 1985 | 1999 | 34.9 | low | 0 | 15 | 9 | 0 | 0 | 0 |
| Itching | 0 | | 2004 | 2007 | 18.7 | low | 0 | 0 | 0 | 3 | 0 | 0 |
| Jaundice | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Jaundice, Neonatal | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Jaundice, Spirochetal | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Jaw Diseases | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Joint Diseases | 0 | | 1992 | 1996 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Kahler Disease | 0 | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Kawasaki Disease | 0 | | 1988 | 1991 | 35.0 | low | 1 | 2 | 1 | 0 | 0 | 0 |
| Keratocysts | 0 | | 1984 | 1986 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Kidney Diseases | 0 | | 1986 | 2013 | 28.5 | low | 3 | 9 | 9 | 8 | 1 | 0 |
| Kidney Failure | 0 | | 1999 | 2015 | 17.0 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Kidney Failure, Chronic | 0 | | 1981 | 2007 | 35.0 | low | 2 | 17 | 6 | 4 | 0 | 0 |
| Kidney Neoplasms | 0 | | 1986 | 2010 | 29.0 | low | 1 | 2 | 1 | 1 | 0 | 0 |
| Kidney Tubular Necrosis, Acute | 0 | | 1987 | 1998 | 33.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Kidney, Polycystic | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Labor, Premature | 0 | | 1981 | 2000 | 33.0 | low | 1 | 4 | 5 | 0 | 0 | 0 |
| Laryngeal Neoplasms | 0 | | 1990 | 1993 | 32.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Laryngitis | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Left Ventricular Dysfunction | 0 | | 1998 | 2000 | 25.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Left Ventricular Hypertrophy | 0 | | 1993 | 1994 | 30.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Left Ventricular Outflow Obstruction | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Leiomyoma | 0 | | 1985 | 1992 | 35.5 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| Leucocythaemia | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Leukemia | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Leukemia, Basophilic, Acute | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Leukemia, Lymphocytic | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Leukemia, Lymphoid | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Leukemia, Myelogenous, Chronic, BCR-ABL Positive | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Leukemia, Myeloid | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Leukemia, Myeloid, Acute | 0 | | 1987 | 1994 | 34.3 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Leukocytopenia | 0 | | 1986 | 2000 | 29.3 | low | 0 | 1 | 8 | 0 | 0 | 0 |
| Leukocytosis | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Leukopenia | 0 | | 1986 | 2000 | 29.3 | low | 0 | 1 | 8 | 0 | 0 | 0 |
| Libman-Sacks Disease | 0 | | 1985 | 1996 | 34.2 | low | 0 | 3 | 3 | 0 | 0 | 0 |
| Lichen Simplex Chronicus | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Liver Cirrhosis | 0 | | 1986 | 2016 | 31.1 | low | 1 | 8 | 9 | 3 | 1 | 0 |
| Liver Cirrhosis, Alcoholic | 0 | | 1986 | 2014 | 27.8 | low | 0 | 2 | 1 | 0 | 1 | 0 |
| Liver Cirrhosis, Biliary | 0 | | 1993 | 2007 | 26.3 | low | 0 | 0 | 2 | 1 | 0 | 0 |
| Liver Diseases | 0 | | 1984 | 2006 | 29.6 | low | 0 | 2 | 7 | 2 | 0 | 0 |
| Liver Diseases, Alcoholic | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Liver Dysfunction | 0 | | 1984 | 2006 | 29.6 | low | 0 | 2 | 7 | 2 | 0 | 0 |
| Liver Failure | 0 | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Liver Failure, Acute | 0 | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Liver Neoplasms | 0 | | 1990 | 2006 | 27.1 | low | 1 | 0 | 4 | 3 | 0 | 0 |
| Liver Steatosis | 0 | | 2004 | 2011 | 16.5 | low | 0 | 0 | 0 | 1 | 1 | 0 |
| Local Neoplasm Recurrence | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Lung Diseases | 0 | | 1981 | 2008 | 32.9 | low | 1 | 17 | 16 | 4 | 0 | 0 |
| Lung Diseases, Interstitial | 0 | | 2001 | 2001 | 23.0 | low | 1 | 0 | 0 | 1 | 0 | 0 |
| Lung Diseases, Obstructive | 0 | | 1984 | 2010 | 30.5 | low | 0 | 1 | 4 | 1 | 0 | 0 |
| Lung Neoplasms | 0 | | 1984 | 2004 | 30.0 | low | 1 | 4 | 4 | 3 | 0 | 0 |
| Lupus Erythematosus, Systemic | 0 | | 1985 | 1996 | 34.2 | low | 0 | 3 | 3 | 0 | 0 | 0 |
| Lupus Nephritis | 0 | | 1987 | 2001 | 28.7 | low | 1 | 1 | 4 | 1 | 0 | 0 |
| Lymph Node Metastasis | 0 | | 1983 | 1993 | 37.2 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Lymphatic Diseases | 0 | | 1981 | 1986 | 40.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Lymphoma | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Lymphoma, Non-Hodgkin | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Maculopapular Cutaneous Mastocytosis | 0 | | 1983 | 1999 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Magnesium Deficiency | 0 | | 1986 | 2008 | 26.7 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Malaria | 0 | | 1984 | 1986 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Marasmus | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Mastitis, Bovine | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Maxillary Neoplasms | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Meconium Aspiration Syndrome | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Meningeal Neoplasms | 0 | | 1984 | 1993 | 34.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Meningioma | 0 | | 1984 | 1993 | 34.7 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Meningitis | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Menopause | 0 | | 1982 | 1993 | 37.1 | low | 0 | 8 | 2 | 0 | 0 | 0 |
| Menorrhagia | 0 | | 1981 | 1992 | 37.5 | low | 0 | 3 | 1 | 0 | 0 | 0 |
| Menstruation, Painful | 0 | | 1983 | 2011 | 26.0 | low | 3 | 1 | 3 | 2 | 1 | 0 |
| Mesenteric Vascular Occlusion | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Metabolic Acidosis | 0 | | 1992 | 1998 | 29.8 | low | 0 | 0 | 5 | 0 | 0 | 0 |
| Metabolic Syndrome | 0 | | 2006 | 2016 | 13.0 | low | 0 | 0 | 0 | 3 | 2 | 0 |
| Metastase | 0 | | 1981 | 2002 | 37.4 | low | 0 | 7 | 0 | 1 | 0 | 0 |
| Metrorrhagia | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Middle Ear Effusion | 0 | | 1988 | 1991 | 34.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Middle Ear Inflammation | 0 | | 1988 | 1998 | 31.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Migraine Disorders | 0 | | 1985 | 2007 | 33.0 | low | 0 | 5 | 1 | 1 | 0 | 0 |
| Mitral Incompetence | 0 | | 1985 | 2010 | 26.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| Mitral Stenosis | 0 | | 1990 | 1999 | 29.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Mitral Valve Insufficiency | 0 | | 1985 | 2010 | 26.5 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| Mitral Valve Stenosis | 0 | | 1990 | 1999 | 29.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| MODS | 0 | | 1991 | 2005 | 28.8 | low | 1 | 0 | 11 | 1 | 0 | 0 |
| Morphine Abuse | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Morphine Dependence | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Mouth Neoplasms | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| MS (Multiple Sclerosis) | 0 | | 1985 | 1989 | 37.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Mucocutaneous Lymph Node Syndrome | 0 | | 1988 | 1991 | 35.0 | low | 1 | 2 | 1 | 0 | 0 | 0 |
| Multiple Myeloma | 0 | | 2006 | 2006 | 18.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Multiple Organ Failure | 0 | | 1991 | 2005 | 28.8 | low | 1 | 0 | 11 | 1 | 0 | 0 |
| Multiple Sclerosis | 0 | | 1985 | 1989 | 37.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Muscle Contraction | 0 | | 1980 | 2017 | 32.5 | low | 1 | 30 | 25 | 8 | 3 | 0 |
| Muscle Relaxation | 0 | | 1985 | 2014 | 28.3 | low | 0 | 6 | 10 | 4 | 1 | 0 |
| Muscle Spasm | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Myelopathy | 0 | | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Myeloproliferative Disorders | 0 | | 1985 | 1991 | 36.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Myocardial Infarction | 0 | | 1981 | 2018 | 29.4 | low | 6 | 26 | 31 | 13 | 4 | 0 |
| Myocardial Ischemia | 0 | | 1992 | 2016 | 24.7 | low | 4 | 0 | 19 | 7 | 1 | 0 |
| Myositis | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Nasal Catarrh | 0 | | 1993 | 1997 | 29.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Nasal Polyps | 0 | | 1987 | 2000 | 29.8 | low | 0 | 1 | 4 | 0 | 0 | 0 |
| Nausea | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Necrosis | 0 | | 1984 | 1998 | 32.4 | low | 0 | 2 | 6 | 0 | 0 | 0 |
| Necrotizing Pyelonephritis | 0 | | 1982 | 1997 | 34.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Neoplasm Metastasis | 0 | | 1981 | 2002 | 37.4 | low | 0 | 7 | 0 | 1 | 0 | 0 |
| Neoplasms | 0 | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Neoplasms, Germ Cell and Embryonal | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Nephritis | 0 | | 1987 | 1995 | 33.2 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| Nephritis, Interstitial | 0 | | 1994 | 1994 | 30.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Nephrosis | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Nephrosis, Lipoid | 0 | | 1986 | 2000 | 32.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Nephrotic Syndrome | 0 | | 1982 | 2005 | 31.1 | low | 2 | 3 | 4 | 1 | 0 | 0 |
| Nervous System Diseases | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Nervous System Disorders | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Neurodermatitis | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Neutropenia | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Obesity | 0 | | 1996 | 2015 | 19.6 | low | 1 | 0 | 4 | 4 | 2 | 0 |
| Obstructive Lung Diseases | 0 | | 1984 | 2010 | 30.5 | low | 0 | 1 | 4 | 1 | 0 | 0 |
| Oligomenorrhea | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Osteoarthritis | 0 | | 1991 | 2004 | 26.5 | low | 1 | 0 | 3 | 1 | 0 | 0 |
| Osteogenic Sarcoma | 0 | | 1983 | 1997 | 34.8 | low | 0 | 3 | 2 | 0 | 0 | 0 |
| Osteoid Osteoma | 0 | | 1991 | 1992 | 32.7 | low | 0 | 0 | 3 | 0 | 0 | 0 |
| Osteomyelitis | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Osteosarcoma | 0 | | 1983 | 1997 | 34.8 | low | 0 | 3 | 2 | 0 | 0 | 0 |
| Otitis Media | 0 | | 1988 | 1998 | 31.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Otitis Media with Effusion | 0 | | 1988 | 1991 | 34.3 | low | 0 | 1 | 2 | 0 | 0 | 0 |
| Ovarian Diseases | 0 | | 1994 | 1994 | 30.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Ovarian Hyperstimulation Syndrome | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Ovarian Hyperstimulation Syndrome, Familial Gestational Spontaneous | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Ovarian Neoplasms | 0 | | 1983 | 2002 | 35.7 | low | 1 | 5 | 0 | 1 | 0 | 0 |
| Ovine Diseases | 0 | | 1985 | 1991 | 37.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Pachymeningitis | 0 | | 1989 | 1989 | 35.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Pain | 0 | | 1984 | 2016 | 26.2 | low | 1 | 2 | 5 | 1 | 1 | 0 |
| Pain, Postoperative | 0 | | 1987 | 2008 | 24.3 | low | 3 | 1 | 0 | 2 | 0 | 0 |
| Palmoplantaris Pustulosis | 0 | | 1983 | 1989 | 37.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Pancreatic Neoplasms | 0 | | 1984 | 2004 | 27.3 | low | 0 | 1 | 0 | 2 | 0 | 0 |
| Pancreatitis | 0 | | 1985 | 2007 | 31.2 | low | 0 | 5 | 10 | 2 | 0 | 0 |
| Paramyxoviridae Infections | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Parasitemia | 0 | | 2013 | 2013 | 11.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Parodontosis | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Paroxysmal Reciprocal Tachycardia | 0 | | 1986 | 2006 | 28.0 | low | 1 | 1 | 0 | 1 | 0 | 0 |
| Patency of the Ductus Arteriosus | 0 | | 1984 | 2008 | 34.4 | low | 3 | 11 | 1 | 2 | 0 | 0 |
| Pelvic Inflammatory Disease | 0 | | 1984 | 1986 | 39.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Peptic Ulcer | 0 | | 1985 | 2016 | 32.3 | low | 0 | 5 | 4 | 0 | 1 | 0 |
| Periapical Cyst | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Pericementitis | 0 | | 1985 | 2006 | 32.2 | low | 0 | 2 | 1 | 1 | 0 | 0 |
| Periodontal Diseases | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Periodontal Pocket | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Periodontitis | 0 | | 1985 | 2006 | 32.2 | low | 0 | 2 | 1 | 1 | 0 | 0 |
| Peritonitis | 0 | | 1982 | 2002 | 34.8 | low | 0 | 10 | 5 | 2 | 0 | 0 |
| Persistent Fetal Circulation Syndrome | 0 | | 1990 | 1991 | 33.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Phlegmasia Alba Dolens | 0 | | 1987 | 1996 | 32.7 | low | 1 | 2 | 4 | 0 | 0 | 0 |
| Phobic Disorders | 0 | | 1984 | 1984 | 40.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| Pituitary Neoplasms | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Placenta Diseases | 0 | | 1981 | 2012 | 26.0 | low | 0 | 1 | 1 | 2 | 1 | 0 |
| Placental Abruption | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Placental Insufficiency | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Plant Poisoning | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Pleural Effusion | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Pleurisy | 0 | | 1984 | 2003 | 31.7 | low | 0 | 5 | 9 | 1 | 0 | 0 |
| Plica Syndrome | 0 | | 1983 | 1992 | 36.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Pneumococcal Infections | 0 | | 1991 | 1998 | 29.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Pneumonia | 0 | | 1985 | 2009 | 31.6 | low | 0 | 3 | 2 | 2 | 0 | 0 |
| Pneumonia, Pneumococcal | 0 | | 1987 | 2003 | 29.0 | low | 0 | 1 | 0 | 1 | 0 | 0 |
| Pocket, Periodontal | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Poliomyelitis | 0 | | 2011 | 2011 | 13.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Polyarthritis | 0 | | 1989 | 1998 | 30.0 | low | 3 | 1 | 3 | 0 | 0 | 0 |
| Polycystic Kidney Diseases | 0 | | 2009 | 2009 | 15.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Polycystic Kidney, Autosomal Dominant | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Polycythemia Vera | 0 | | 1985 | 1991 | 36.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Polyuria | 0 | | 1985 | 2000 | 31.6 | low | 2 | 3 | 4 | 0 | 0 | 0 |
| Post-operative Vasoplegic Syndrome | 0 | | 2019 | 2019 | 5.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Postoperative Complications | 0 | | 1986 | 2019 | 24.6 | low | 3 | 4 | 3 | 3 | 3 | 0 |
| Postpartum Hemorrhage | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Potassium Deficiency | 0 | | 1989 | 1992 | 34.2 | low | 1 | 3 | 1 | 0 | 0 | 0 |
| Pre-Eclampsia | 0 | | 1981 | 2015 | 31.3 | low | 6 | 29 | 46 | 7 | 1 | 0 |
| Pre-Hypertension | 0 | | 2013 | 2013 | 11.0 | low | 1 | 0 | 0 | 0 | 1 | 0 |
| Precursor Cell Lymphoblastic Leukemia-Lymphoma | 0 | | 1988 | 1994 | 33.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Pregnancy | 0 | | 1980 | 2020 | 33.5 | low | 15 | 191 | 147 | 23 | 8 | 0 |
| Pregnancy in Diabetes | 0 | | 1981 | 2002 | 33.5 | low | 0 | 8 | 7 | 2 | 0 | 0 |
| Premenstrual Syndrome | 0 | | 1985 | 1985 | 39.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| Premenstrual Tension | 0 | | 1985 | 1985 | 39.0 | low | 1 | 1 | 0 | 0 | 0 | 0 |
| Primary Myelofibrosis | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Primary Peritonitis | 0 | | 1982 | 2002 | 34.8 | low | 0 | 10 | 5 | 2 | 0 | 0 |
| Prinzmetal Angina | 0 | | 1985 | 1985 | 39.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Prostatic Hyperplasia | 0 | | 1981 | 1981 | 43.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Prostatic Neoplasms | 0 | | 1981 | 2002 | 34.7 | low | 0 | 2 | 0 | 1 | 0 | 0 |
| Prostatitis | 0 | | 2002 | 2002 | 22.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Protein-Energy Malnutrition | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Proteinuria | 0 | | 1982 | 2007 | 29.6 | low | 1 | 6 | 17 | 6 | 0 | 0 |
| Pruritus | 0 | | 2004 | 2007 | 18.7 | low | 0 | 0 | 0 | 3 | 0 | 0 |
| Pseudomonas Infections | 0 | | 1985 | 1990 | 37.1 | low | 0 | 6 | 1 | 0 | 0 | 0 |
| Psoriasis | 0 | | 1983 | 1989 | 37.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Puerperal Disorders | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Pulmonary Arterial Remodeling | 0 | | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Pulmonary Disease, Chronic Obstructive | 0 | | 2012 | 2012 | 12.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Pulmonary Edema | 0 | | 1982 | 2004 | 34.1 | low | 0 | 17 | 15 | 2 | 0 | 0 |
| Pulmonary Embolism | 0 | | 1981 | 2014 | 33.6 | low | 0 | 14 | 3 | 4 | 1 | 0 |
| Pulmonary Fibrosis | 0 | | 1982 | 1994 | 37.7 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Pulmonary Hypertension | 0 | | 1982 | 2021 | 30.0 | low | 2 | 29 | 30 | 13 | 3 | 1 |
| Pulpitis | 0 | | 1987 | 1999 | 31.2 | low | 0 | 2 | 2 | 0 | 0 | 0 |
| Purpura, Thrombocytopenic | 0 | | 1985 | 1989 | 37.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Purpura, Thrombopenic | 0 | | 1985 | 1989 | 37.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Purpura, Thrombotic Thrombocytopenic | 0 | | 1981 | 1986 | 41.0 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| Pyelonephritis | 0 | | 1982 | 1997 | 34.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Pyometra | 0 | | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Pyrexia | 0 | | 1985 | 2016 | 26.7 | low | 1 | 1 | 1 | 0 | 1 | 0 |
| Raynaud Disease | 0 | | 1981 | 2018 | 33.6 | low | 2 | 9 | 2 | 0 | 1 | 0 |
| Recrudescence | 0 | | 1986 | 2004 | 31.4 | low | 1 | 2 | 7 | 1 | 0 | 0 |
| Renal Artery Obstruction | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Renal Artery Stenosis | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Renal Insufficiency | 0 | | 1999 | 2015 | 17.0 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Reperfusion Injury | 0 | | 1988 | 2016 | 25.5 | low | 1 | 1 | 35 | 17 | 4 | 0 |
| Reproductive Sterility | 0 | | 1984 | 1996 | 34.0 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Respiratory Distress Syndrome | 0 | | 1984 | 2004 | 30.9 | low | 3 | 10 | 14 | 2 | 0 | 0 |
| Respiratory Distress Syndrome, Newborn | 0 | | 1982 | 2002 | 35.5 | low | 2 | 13 | 3 | 1 | 0 | 0 |
| Respiratory Insufficiency | 0 | | 1984 | 1991 | 36.6 | low | 0 | 5 | 2 | 0 | 0 | 0 |
| Respiratory Syncytial Virus Infections | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Respiratory Tract Diseases | 0 | | 1993 | 1997 | 29.0 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| Retinal Artery Occlusion | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Retinal Detachment | 0 | | 1983 | 1988 | 38.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Retinal Pigment Epithelial Detachment | 0 | | 1983 | 1988 | 38.0 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Retinal Vein Occlusion | 0 | | 1993 | 1999 | 28.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Retinopathy of Prematurity | 0 | | 1984 | 1988 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Retrolental Fibroplasia | 0 | | 1984 | 1988 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Rheumatic Heart Disease | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Rheumatoid Arthritis | 0 | | 1981 | 2001 | 35.0 | low | 3 | 11 | 8 | 1 | 0 | 0 |
| Rhinitis | 0 | | 1993 | 1997 | 29.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Rhinitis, Allergic, Seasonal | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Right Ventricular Dysfunction | 0 | | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 2 | 0 |
| Rocky Mountain Spotted Fever | 0 | | 1990 | 2006 | 26.0 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Rupture, Spontaneous | 0 | | 1985 | 1987 | 37.8 | low | 0 | 4 | 0 | 0 | 0 | 0 |
| Salmonella Infections, Animal | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Salpingitis | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Sarcoidosis | 0 | | 1984 | 1984 | 40.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Sarcoma, Ewing | 0 | | 1985 | 1986 | 38.5 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Sarcoma, Synovial | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Scleroderma, Systemic | 0 | | 1983 | 2018 | 32.9 | low | 0 | 5 | 1 | 0 | 1 | 0 |
| Sclerosis, Systemic | 0 | | 1983 | 2018 | 32.9 | low | 0 | 5 | 1 | 0 | 1 | 0 |
| Segond Fracture | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Seizures | 0 | | 1998 | 2014 | 18.0 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Sensitivity and Specificity | 0 | | 1992 | 2012 | 24.1 | low | 0 | 0 | 9 | 4 | 1 | 0 |
| Sepsis | 0 | | 1984 | 2019 | 31.0 | low | 0 | 9 | 10 | 1 | 1 | 0 |
| Shock | 0 | | 1983 | 2003 | 32.5 | low | 1 | 4 | 7 | 1 | 0 | 0 |
| Shock, Septic | 0 | | 1980 | 2008 | 35.2 | low | 0 | 48 | 25 | 3 | 0 | 0 |
| Shock, Surgical | 0 | | 1990 | 1990 | 34.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Shock, Traumatic | 0 | | 1992 | 1993 | 31.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Sinus Infections | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Sinusitis | 0 | | 2000 | 2000 | 24.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Skin Diseases | 0 | | 1983 | 1989 | 38.0 | low | 0 | 2 | 0 | 0 | 0 | 0 |
| Skin Neoplasms | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Sleep Apnea Syndromes | 0 | | 1991 | 1998 | 29.5 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Sleep Apnea, Obstructive | 0 | | 2004 | 2016 | 12.7 | low | 1 | 0 | 0 | 1 | 2 | 0 |
| Smoking Cessation | 0 | | 1992 | 1993 | 31.3 | low | 1 | 0 | 3 | 0 | 0 | 0 |
| Sneezing | 0 | | 1987 | 1987 | 37.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Spasm | 0 | | 1999 | 1999 | 25.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Spinal Cord Diseases | 0 | | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Spinal Cord Injuries | 0 | | 1985 | 2007 | 30.4 | low | 0 | 5 | 5 | 3 | 0 | 0 |
| Spinal Cord Neoplasms | 0 | | 1988 | 1988 | 36.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Spinal Diseases | 0 | | 2007 | 2007 | 17.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Sterility, Female | 0 | | 1981 | 2001 | 36.1 | low | 0 | 5 | 1 | 1 | 0 | 0 |
| Sterility, Male | 0 | | 1979 | 1979 | 45.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Stomach Neoplasms | 0 | | 1998 | 2001 | 24.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Stomach Ulcer | 0 | | 1983 | 2015 | 29.3 | low | 0 | 14 | 9 | 7 | 3 | 0 |
| Stomatitis, Aphthous | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Streptococcal Infections | 0 | | 1984 | 1993 | 36.0 | low | 0 | 6 | 3 | 0 | 0 | 0 |
| Stroke | 0 | | 2000 | 2015 | 14.5 | low | 1 | 0 | 1 | 1 | 2 | 0 |
| Subarachnoid Hemorrhage | 0 | | 1983 | 2012 | 34.9 | low | 1 | 16 | 6 | 0 | 1 | 0 |
| Substance Withdrawal Syndrome | 0 | | 1987 | 1996 | 34.0 | low | 0 | 2 | 1 | 0 | 0 | 0 |
| Substance-Related Disorders | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Suffocation | 0 | | 1996 | 1996 | 28.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Swine Diseases | 0 | | 1998 | 2013 | 18.5 | low | 0 | 0 | 1 | 0 | 1 | 0 |
| Symptom Cluster | 0 | | 1981 | 2019 | 27.1 | low | 6 | 6 | 6 | 4 | 2 | 0 |
| Syndrome | 0 | | 1981 | 2019 | 27.1 | low | 6 | 6 | 6 | 4 | 2 | 0 |
| Synovioma | 0 | | 1985 | 1985 | 39.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Synovitis | 0 | | 1983 | 1992 | 36.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Systemic Inflammatory Response Syndrome | 0 | | 1996 | 2001 | 25.7 | low | 1 | 0 | 2 | 1 | 0 | 0 |
| Tachyarrhythmia | 0 | | 1989 | 2017 | 21.4 | low | 3 | 1 | 1 | 2 | 1 | 0 |
| Tachycardia | 0 | | 1989 | 2017 | 21.4 | low | 3 | 1 | 1 | 2 | 1 | 0 |
| Tachycardia, Paroxysmal | 0 | | 1986 | 2006 | 28.0 | low | 1 | 1 | 0 | 1 | 0 | 0 |
| Tachycardia, Supraventricular | 0 | | 1986 | 2006 | 28.0 | low | 1 | 1 | 0 | 1 | 0 | 0 |
| Takayasu Arteritis | 0 | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Temporomandibular Disorders | 0 | | 1998 | 1998 | 26.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Temporomandibular Joint Disorders | 0 | | 1998 | 1998 | 26.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Tetralogy of Fallot | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Thalassemia | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Thalassemias | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Thrombocythemia | 0 | | 1982 | 1987 | 39.3 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| Thrombocythemia, Essential | 0 | | 1991 | 2014 | 19.0 | low | 1 | 0 | 1 | 1 | 1 | 0 |
| Thrombocytopathy | 0 | | 1990 | 1993 | 32.5 | low | 1 | 0 | 2 | 0 | 0 | 0 |
| Thrombocytopenia | 0 | | 1980 | 1994 | 38.0 | low | 1 | 11 | 4 | 0 | 0 | 0 |
| Thromboembolism | 0 | | 1991 | 2004 | 26.3 | low | 0 | 0 | 3 | 3 | 0 | 0 |
| Thrombopenia | 0 | | 1980 | 1994 | 38.0 | low | 1 | 11 | 4 | 0 | 0 | 0 |
| Thrombophilia | 0 | | 2004 | 2004 | 20.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Thrombophlebitis | 0 | | 1987 | 1996 | 32.7 | low | 1 | 2 | 4 | 0 | 0 | 0 |
| Thrombosis | 0 | | 1982 | 2022 | 26.4 | low | 4 | 21 | 28 | 15 | 9 | 2 |
| Tibial Fractures | 0 | | 1998 | 1998 | 26.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Toxemia | 0 | | 1985 | 1995 | 34.8 | low | 0 | 3 | 2 | 0 | 0 | 0 |
| Trichostrongylosis | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Ulcer | 0 | | 1988 | 2014 | 23.0 | low | 0 | 1 | 0 | 0 | 1 | 0 |
| Uremia | 0 | | 1980 | 2005 | 35.3 | low | 0 | 6 | 3 | 1 | 0 | 0 |
| Ureteral Obstruction | 0 | | 1981 | 2005 | 30.8 | low | 0 | 2 | 6 | 1 | 0 | 0 |
| Urethral Obstruction | 0 | | 2001 | 2001 | 23.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Urinary Incontinence | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Urogenital Neoplasms | 0 | | 1986 | 1986 | 38.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Urticaria | 0 | | 1991 | 1991 | 33.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Uterine Diseases | 0 | | 1996 | 2001 | 25.5 | low | 0 | 0 | 1 | 1 | 0 | 0 |
| Uterine Hemorrhage | 0 | | 2020 | 2020 | 4.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Uterine Neoplasms | 0 | | 1984 | 1992 | 36.1 | low | 0 | 5 | 4 | 0 | 0 | 0 |
| Vaginosis, Bacterial | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Varices | 0 | | 1985 | 1999 | 32.2 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| Varicose Veins | 0 | | 1985 | 1999 | 32.2 | low | 0 | 1 | 3 | 0 | 0 | 0 |
| Vascular Diseases | 0 | | 1985 | 2008 | 31.5 | low | 1 | 7 | 4 | 2 | 0 | 0 |
| Vasculitis | 0 | | 2005 | 2005 | 19.0 | low | 0 | 0 | 0 | 1 | 0 | 0 |
| Vasospasm, Intracranial | 0 | | 2012 | 2012 | 12.0 | low | 1 | 0 | 0 | 0 | 1 | 0 |
| Venous Insufficiency | 0 | | 1992 | 1996 | 30.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Venous Thrombosis | 0 | | 2001 | 2020 | 13.1 | low | 1 | 0 | 0 | 2 | 5 | 0 |
| Ventricular Dysfunction, Left | 0 | | 1998 | 2000 | 25.0 | low | 0 | 0 | 2 | 0 | 0 | 0 |
| Ventricular Fibrillation | 0 | | 1984 | 1995 | 34.4 | low | 0 | 2 | 3 | 0 | 0 | 0 |
| Vesico-Ureteral Reflux | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Vesicoureteral Reflux | 0 | | 1997 | 1997 | 27.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Viral Hepatitis, Human | 0 | | 1992 | 1992 | 32.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Vitamin D Deficiency | 0 | | 2019 | 2019 | 5.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
| Vitiligo | 0 | | 1983 | 1983 | 41.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Vomiting | 0 | | 1982 | 1987 | 38.7 | low | 0 | 3 | 0 | 0 | 0 | 0 |
| von Willebrand Diseases | 0 | | 1987 | 1990 | 35.5 | low | 0 | 1 | 1 | 0 | 0 | 0 |
| Water Intoxication | 0 | | 1992 | 1992 | 32.0 | low | 1 | 0 | 1 | 0 | 0 | 0 |
| Water-Electrolyte Imbalance | 0 | | 1982 | 1982 | 42.0 | low | 0 | 1 | 0 | 0 | 0 | 0 |
| Weight Gain | 0 | | 1989 | 2003 | 28.7 | low | 0 | 1 | 1 | 1 | 0 | 0 |
| Weight Loss | 0 | | 2003 | 2004 | 20.7 | low | 0 | 0 | 0 | 3 | 0 | 0 |
| Weight Reduction | 0 | | 2003 | 2004 | 20.7 | low | 0 | 0 | 0 | 3 | 0 | 0 |
| Wounds and Injuries | 0 | | 1986 | 1996 | 34.8 | low | 0 | 4 | 1 | 0 | 0 | 0 |
| Zellweger Syndrome | 0 | | 1993 | 1993 | 31.0 | low | 0 | 0 | 1 | 0 | 0 | 0 |
| Zika Virus Infection | 0 | | 2020 | 2020 | 4.0 | low | 0 | 0 | 0 | 0 | 1 | 0 |
Immunosuppressive therapy for recurrent aborters with positive antiphospholipid antibodies and alteration of 6ketoPGF1 alpha/TXB2 ratio.Journal of perinatal medicine, , Volume: 25, Issue:6, 1997
Thromboxane dominance and prostacyclin deficiency in habitual abortion.Lancet (London, England), , Apr-13, Volume: 337, Issue:8746, 1991
Lupus anticoagulant, recurrent abortion, and prostacyclin production by cultured smooth muscle cells.Lancet (London, England), , Nov-12, Volume: 2, Issue:8359, 1983
Response of intra-acinar pulmonary microvessels to hypoxia, hypercapnic acidosis, and isocapnic acidosis.Circulation research, , Apr-06, Volume: 82, Issue:6, 1998
Portal infusion of low dosage endotoxin: a model simulating translocation of ruminal endotoxin in cattle.Acta veterinaria Scandinavica, , Volume: 35, Issue:1, 1994
Endotoxin and arachidonic acid metabolites in portal, hepatic and arterial blood of cattle with acute ruminal acidosis.Acta veterinaria Scandinavica, , Volume: 35, Issue:3, 1994
Tumor necrosis factor-induced mortality is reversed with cyclooxygenase inhibition.Annals of surgery, , Volume: 217, Issue:6, 1993
[Plasma renin activity, angiotensin II, angiotensin converting enzyme, thromboxane A2 and prostacyclin I2 levels in pigs with severe hypoxia and hypercapnea and acidosis shock].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 15, Issue:1, 1992
Activation of sensory neurons reduces ischemia/reperfusion-induced acute renal injury in rats.Anesthesiology, , Volume: 110, Issue:2, 2009
Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation.Cardiovascular research, , Feb-01, Volume: 81, Issue:2, 2009
Low dose rofecoxib, inflammation and prostacyclin synthesis in acute coronary syndromes.Roczniki Akademii Medycznej w Bialymstoku (1995), , Volume: 50, 2005
Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage.Thrombosis research, , Volume: 115, Issue:5, 2005
The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids.Hepatobiliary & pancreatic diseases international : HBPD INT, , Volume: 2, Issue:3, 2003
[Effect of yinchen dandao decoction on plasma fibronectin, biliary thromboxane A2 and prostaglandin I2 in human and animal suffering from acute cholangitis].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 20, Issue:12, 2000
The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation.Stroke, , Volume: 31, Issue:6, 2000
The role of prostanoids and nitric oxide in endotoxin-induced hyporesponsiveness of equine digital blood vessels.Equine veterinary journal, , Volume: 31, Issue:3, 1999
Expression of acute otitis media after receptor blockade of platelet activating factor, thromboxane, and leukotrienes in the chinchilla.The Annals of otology, rhinology, and laryngology, , Volume: 107, Issue:3, 1998
Acute stress in rats produces a rapid and sustained increase in prostacyclin production in aortic tissue: dependence on corticosterone.Life sciences, , Volume: 57, Issue:1, 1995
Acute burn down regulates rabbit splanchnic and renal prostanoid release.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:3, 1995
Prostanoids and oxygen free radicals in early stages of experimental acute pancreatitis.Digestive diseases and sciences, , Volume: 39, Issue:7, 1994
Lipid mediator production in acute and chronic pancreatitis in the rat.The Journal of surgical research, , Volume: 56, Issue:1, 1994
[The functional characteristics of the prostacyclin-thromboxane system in newborn infants with a history of acute and chronic intrauterine hypoxia].Akusherstvo i ginekologiia, , Issue:6, 1993
Thromboxane and prostacyclin synthesis in experimental pancreas transplantation. Changes in parenchymal and vascular prostanoids.Transplantation, , Volume: 56, Issue:6, 1993
Changes of systemic prostacyclin and thromboxane A2 in sodium taurocholate- and cerulein-induced acute pancreatitis in rats.Digestive diseases and sciences, , Volume: 38, Issue:1, 1993
Cyclooxygenase and lipoxygenase metabolism in sodium taurocholate induced acute hemorrhagic pancreatitis in rats.Prostaglandins, , Volume: 45, Issue:4, 1993
Evidence of acute inflammatory response in reexpansion pulmonary edema.Chest, , Volume: 101, Issue:1, 1992
Effects of long-acting somatostatin analog (SMS 201-995) on eicosanoid synthesis and survival in rats with acute necrotizing pancreatitis.Digestive diseases and sciences, , Volume: 37, Issue:9, 1992
Pretreatment with catalase or dimethyl sulfoxide protects alloxan-induced acute lung edema in dogs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:4, 1992
The involvement of platelet-activating factor in hyperacute xenogeneic rejection and its modulation by the PAF-antagonist WEB 2086BS.Transplantation proceedings, , Volume: 23, Issue:1 Pt 1, 1991
Prostacyclin concentrations in haemolytic uraemic syndrome after acute shigellosis in children.Archives of disease in childhood, , Volume: 66, Issue:10, 1991
[Effects of verapamil on prostacyclin, thromboxane and pancreatic blood flow of rats with experimental acute pancreatitis].Zhonghua yi xue za zhi, , Volume: 71, Issue:9, 1991
[Status of the prostacyclin-thromboxane balance in patients with cerebrovascular disorders and the effect of the treatment with nifedipine].Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), , Volume: 91, Issue:7, 1991
Local and systemic effects of an acute inflammation on eicosanoid generation capacity of polymorphonuclear cells and macrophages.International journal of experimental pathology, , Volume: 71, Issue:5, 1990
The role of prostanoids in the production of acute acalculous cholecystitis by platelet-activating factor.Annals of surgery, , Volume: 212, Issue:4, 1990
[Plasma level and effects of thromboxane A2 and 6-keto-PGF1 alpha in patients with acute obstructive suppurative cholangitis].Zhonghua wai ke za zhi [Chinese journal of surgery], , Volume: 28, Issue:4, 1990
Effect of acute ethanol ingestion on human gastric luminal prostaglandin E2, prostaglandin F2 alpha and 6-keto-prostaglandin F1 alpha.Alcohol and alcoholism (Oxford, Oxfordshire), , Volume: 24, Issue:1, 1989
Corticosteroids prevent acute lung dysfunction caused by thoracic irradiation in unanesthetized sheep.The American review of respiratory disease, , Volume: 138, Issue:5, 1988
Prostanoid imbalance in experimental acute necrotizing pancreatitis in rats.Scandinavian journal of gastroenterology, , Volume: 23, Issue:2, 1988
Effects of methylprednisolone on acute lung paraquat toxicity in sheep.The American review of respiratory disease, , Volume: 137, Issue:1, 1988
Effects of acute pressure overload on prostacyclin release and myocardial blood flow in canine hearts: inhibition of prostacyclin synthesis with 15-hydroperoxy-eicosatetraenoic acid.Heart and vessels, , Volume: 3, Issue:1, 1987
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs.The Journal of surgical research, , Volume: 42, Issue:3, 1987
Prostaglandin and thromboxane levels during endotoxin-induced respiratory failure in pigs.Prostaglandins, leukotrienes, and medicine, , Volume: 28, Issue:3, 1987
Platelet function in acute respiratory failure.American journal of hematology, , Volume: 25, Issue:4, 1987
Effect of ionizing radiation on prostaglandins and gastric secretion in rhesus monkeys.Radiation research, , Volume: 110, Issue:2, 1987
Platelet function in experimentally induced pancreatitis in the dog.Thrombosis and haemostasis, , Apr-30, Volume: 55, Issue:2, 1986
The behaviour of prostanoids during the course of acute experimental pancreatitis in rats.Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, , Volume: 186, Issue:6, 1986
A comparison of the acute inflammatory response in adrenalectomised and sham-operated rats.British journal of pharmacology, , Volume: 87, Issue:1, 1986
Cyclooxygenase blockade elevates leukotriene E4 production during acute anaphylaxis in sheep.The Journal of experimental medicine, , Jun-01, Volume: 163, Issue:6, 1986
Renin-angiotensin system and glomerular prostaglandins in early nephrotoxicity of ciclosporin.Contributions to nephrology, , Volume: 51, 1986
Failure of exogenous prostacyclin to change placental and fetal blood flow in preeclampsia.American journal of obstetrics and gynecology, , Mar-01, Volume: 151, Issue:5, 1985
Effect of prostaglandin blockers on ascites fluid in pancreatitis.Surgery, , Volume: 98, Issue:3, 1985
Follow-up of prostaglandin plasma levels after acute myocardial infarction.American heart journal, , Volume: 109, Issue:2, 1985
A longitudinal study of the prostaglandin content of central nervous system tissues from guinea pigs with acute experimental allergic encephalomyelitis (EAE).International journal of immunopharmacology, , Volume: 6, Issue:2, 1984
Role of serotonin in patients with acute respiratory failure.Annals of surgery, , Volume: 200, Issue:2, 1984
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01).Thrombosis research, , Dec-01, Volume: 28, Issue:5, 1982
Increased plasma levels of 6-oxo-prostaglandin F1 alpha, a stable metabolite of prostacyclin, in acute kidney transplant rejection.Prostaglandins and medicine, , Volume: 7, Issue:1, 1981
Enhanced prostacyclin synthesis in acute human kidney transplant rejection.Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, , Volume: 17, 1980
[Prostaglandins content in the blood of newborns with various types of hypoxia].Fiziologicheskii zhurnal, , Volume: 39, Issue:2-3
Effect of the ultrashort-acting beta-blocker Brevibloc on free-radical-mediated injuries during the early reperfusion state.Basic research in cardiology, , Volume: 86, Issue:5
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.International journal of gastrointestinal cancer, , Volume: 32, Issue:1, 2002
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion.Clinical & experimental metastasis, , Volume: 19, Issue:7, 2002
Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells.Laboratory investigation; a journal of technical methods and pathology, , Volume: 81, Issue:3, 2001
Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP).Carcinogenesis, , Volume: 21, Issue:8, 2000
[Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 17, Issue:9, 1997
Urinary excretion of prostacyclin and thromboxane degradation products in patients with ovarian malignancy: effect of cytostatic treatment.British journal of cancer, , Volume: 60, Issue:5, 1989
Altered 1-14C arachidonic acid metabolism in arterial wall from patients with renal cell carcinoma.The Journal of urology, , Volume: 135, Issue:5, 1986
Formation of prostaglandins by ovarian carcinomas.Prostaglandins, , Volume: 29, Issue:5, 1985
[Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation].Kyobu geka. The Japanese journal of thoracic surgery, , Volume: 37, Issue:10, 1984
Prostaglandin concentrations and prostaglandin synthetase activity in N-nitrosomethylurea-induced rat mammary adenocarcinoma.European journal of cancer & clinical oncology, , Volume: 19, Issue:6, 1983
[Prostanoids of the peritoneal fluid and sterility with or without pelvic lesions (endometriosis, postinfectious adhesions)].Pathologie-biologie, , Volume: 34, Issue:2, 1986
Peritoneal fluid prostaglandins and prostanoids in women with endometriosis, chronic pelvic inflammatory disease, and pelvic pain.American journal of obstetrics and gynecology, , Feb-15, Volume: 148, Issue:4, 1984
Trans-10,cis-12-conjugated linoleic acid worsens renal pathology and alters cyclooxygenase derived oxylipins in obesity-associated nephropathy.The Journal of nutritional biochemistry, , Volume: 26, Issue:2, 2015
A role for cyclooxygenase in aging-related changes of beta-adrenoceptor-mediated relaxation in rat aortas.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 375, Issue:4, 2007
[Some mechanisms of the development of endothelial disfunction in aging].Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), , Volume: 50, Issue:2, 2004
Effects of exercise on platelet and aortic functions in aged rats.Acta physiologica Scandinavica, , Volume: 179, Issue:2, 2003
[Change in intestinal free radical and prostaglandin metabolism in the aged rats with pneumococcus pneumonia].Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, , Volume: 15, Issue:10, 2003
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes.Life sciences, , Volume: 66, Issue:5, 2000
Excessive vasoconstriction after stress by the aging kidney: inadequate prostaglandin modulation of increased endothelin activity.The Journal of laboratory and clinical medicine, , Volume: 132, Issue:3, 1998
Protectant activity of hexarelin or growth hormone against postischemic ventricular dysfunction in hearts from aged rats.Journal of cardiovascular pharmacology, , Volume: 32, Issue:2, 1998
Mortality and biomarkers of aging in heterogeneous stock (HS) mice.The journals of gerontology. Series A, Biological sciences and medical sciences, , Volume: 53, Issue:3, 1998
Effect of vitamin E supplementation on prostaglandin concentrations in aspirin-induced acute gastric injury in aged rats.The American journal of clinical nutrition, , Volume: 66, Issue:5, 1997
Increased production of tumor necrosis factor and interleukin-6 by arterial wall of aged rats.The American journal of physiology, , Volume: 268, Issue:6 Pt 2, 1995
Age-related reductions in gastric mucosal prostaglandin levels increase susceptibility to aspirin-induced injury in rats.Gastroenterology, , Volume: 107, Issue:6, 1994
Sodium loading and renal prostaglandins in old rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:4, 1993
Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease.Circulation, , Volume: 88, Issue:5 Pt 1, 1993
Age-related differences in responses to endotoxin infusion in unanesthetized piglets.Circulatory shock, , Volume: 41, Issue:1, 1993
Altered prostaglandin synthesis and impaired sodium conservation in the kidneys of old rats.Clinical science (London, England : 1979), , Volume: 83, Issue:3, 1992
Age-associated decreases in prostaglandin contents in human gastric mucosa.Biochemical and biophysical research communications, , Aug-14, Volume: 186, Issue:3, 1992
Effect of aging on endothelin-induced prostaglandin I2 release in isolated hind legs of the spontaneously hypertensive rat.Research communications in chemical pathology and pharmacology, , Volume: 74, Issue:2, 1991
Age does not influence acute aspirin-induced gastric mucosal damage.Gastroenterology, , Volume: 100, Issue:6, 1991
Age-related decline in prostacyclin synthesis by human aortic endothelial cells. Qualitative and quantitative analysis.The American journal of pathology, , Volume: 138, Issue:4, 1991
Non-invasive assessment of the cardiovascular eicosanoids, thromboxane A2 and prostacyclin, in randomly sampled males, with special reference to the influence of inheritance and environmental factors.Clinical science (London, England : 1979), , Volume: 79, Issue:6, 1990
Changes in vascular wall production of prostacyclin and thromboxane A2 in spontaneously hypertensive rats during maturation and the concomitant development of hypertension.Japanese circulation journal, , Volume: 54, Issue:5, 1990
Age-associated reduction of prostacyclin and thromboxane synthesis is inversely related to plasma cholesterol levels: modulation by dietary cholesterol supplementation.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Uniqueness of dietary olive oil in stimulating aortic prostacyclin production in post-weanling rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 36, Issue:1, 1989
Thromboxane A2 and the development of hypertension in spontaneously hypertensive rats.European journal of pharmacology, , Jan-27, Volume: 146, Issue:1, 1988
Platelets and aging. I--Aggregation, arachidonate metabolism and antioxidant status.Thrombosis research, , Feb-01, Volume: 49, Issue:3, 1988
The influence of n-6 and n-3 fatty acids on kidney phospholipid composition and on eicosanoid production in aging rats.Lipids, , Volume: 23, Issue:4, 1988
Nitrates do not affect prostacyclin formation by rat arteries: this is unrelated to increased vascular prostacyclin formation with age.The Journal of pharmacy and pharmacology, , Volume: 39, Issue:12, 1987
Effects of hypothyroidism and short-term aging on whole blood thromboxane and arterial prostacyclin synthesis.The Journal of laboratory and clinical medicine, , Volume: 110, Issue:5, 1987
Ontogeny of 6-keto-PGF1 alpha synthesis in rabbit aorta and the effect of premature weaning.The American journal of physiology, , Volume: 252, Issue:1 Pt 2, 1987
The effect of age on the prostaglandin formation in the rabbit aorta.Artery, , Volume: 13, Issue:4, 1986
Formation of prostacyclin and thromboxane in man as measured by the main urinary metabolites.Biochimica et biophysica acta, , Apr-15, Volume: 876, Issue:2, 1986
Eicosenoid biosynthesis and platelet function with advancing age.Thrombosis research, , Feb-15, Volume: 41, Issue:4, 1986
The influence of age, sex and smoking on human venous prostacyclin synthesis.Thrombosis research, , Feb-01, Volume: 37, Issue:3, 1985
Platelets from aged rats aggregate more, but are more sensitive to prostacyclin.Prostaglandins, leukotrienes, and medicine, , Volume: 20, Issue:3, 1985
Relation of arachidonate metabolites to abnormal control of the pulmonary circulation in a child.The American review of respiratory disease, , Volume: 131, Issue:1, 1985
Continuous monitoring of prostacyclin production by the isolated, intact, rat aorta using a bioassay technique.Journal of pharmacological methods, , Volume: 11, Issue:4, 1984
Streptozotocin-induced diabetes in the neonatal rat: effect on plasma lipids and aortic prostaglandin synthesis in adult life.Biochemical medicine, , Volume: 31, Issue:2, 1984
Effects of age and steroid treatment on prostaglandin production by the rat uterus in relation to implantation.Journal of reproduction and fertility, , Volume: 70, Issue:2, 1984
Changes in prostacyclin and thromboxane biosynthesis and their catabolic enzyme activity in kidneys of aging rats.Life sciences, , Mar-26, Volume: 34, Issue:13, 1984
Levels of plasma 6-keto-PGF1 alpha in normotensive and essential hypertensive males with and without a family history of hypertension.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:1, 1983
In-vitro prostanoid production by the rat vas deferens.Journal of reproduction and fertility, , Volume: 67, Issue:2, 1983
Effect of aging on 6-keto-PGF1 alpha levels in normotensive and essential hypertensive males.Japanese circulation journal, , Volume: 47, Issue:3, 1983
Influence of sex steroids during early development on aortic 6-keto-PGF1 alpha synthesis in adult rats: selective sensitivity to estrogens.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:4, 1983
Changes in arachidonate metabolism in aortas and platelets in aging rats.Prostaglandins, leukotrienes, and medicine, , Volume: 12, Issue:2, 1983
Low prostacyclin synthetase activity of fetal rat aorta. Progressive increase after birth.Life sciences, , Oct-10, Volume: 33, Issue:15, 1983
Prostacyclin from the uterus and woman's cardiovascular advantage.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:5, 1982
[Levels of plasma 6-keto-PGF1 alpha in normotensive and essential hypertensive males with and without a family history of hypertension and effects of aging].Nihon Naibunpi Gakkai zasshi, , Oct-20, Volume: 58, Issue:10, 1982
Plasma prostacyclin from birth to adolescence.Archives of disease in childhood, , Volume: 57, Issue:6, 1982
Analysis of 6-keto-prostaglandin F1 alpha in human urine: age-specific differences.Prostaglandins, , Volume: 23, Issue:1, 1982
The effect of age on circulating 6-keto-prostaglandin F1 alpha in humans.Prostaglandins, leukotrienes, and medicine, , Volume: 9, Issue:5, 1982
The ability of vascular tissue to produce prostacyclin decreases with age.Prostaglandins, , Volume: 21, Issue:3, 1981
Aging: effects on the prostaglandin production by skeletal muscle of male rhesus monkeys (Macaca mulatta).Mechanisms of ageing and development, , Volume: 16, Issue:4, 1981
Prostaglandin production and cellular aging.Mechanisms of ageing and development, , Volume: 16, Issue:4, 1981
Thromboxane B2 production during erection.Andrologia, , Volume: 18, Issue:2
Long-term feeding of corn oil, beef tallow, or menhaden oil and eicosanoid levels in BHE/cdb rats.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 8, Issue:6
Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome.The British journal of nutrition, , Jul-14, Volume: 110, Issue:1, 2013
Suppression of the nitric oxide pathway in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-signaling inhibitors.Hypertension (Dallas, Tex. : 1979), , Volume: 56, Issue:6, 2010
[Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 1, Issue:2, 2003
Elevated renal endothelin-I clearance and mRNA levels associated with albuminuria and nephropathy in non-insulin-dependent diabetes mellitus: studies in obese fa/fa Zucker rats.Clinical science (London, England : 1979), , Volume: 93, Issue:6, 1997
Effect of captopril on renal hemodynamics and renal prostaglandins in early type II diabetic patients with normo-or microalbuminuria.Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, , Volume: 11, Issue:3, 1996
Effect of eicosapentaenoic acid ethyl ester on albuminuria in streptozotocin-induced diabetic rats.Journal of nutritional science and vitaminology, , Volume: 40, Issue:1, 1994
Human and experimental studies on renal eicosanoid response to long-term cadmium exposure.Toxicology and applied pharmacology, , Volume: 116, Issue:2, 1992
The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus.Diabetologia, , Volume: 34, Issue:4, 1991
Effects of thromboxane synthesis inhibitor triflusal on renal hemodynamics in microalbuminuric diabetic patients.Diabetes care, , Volume: 13, Issue:11, 1990
Effects of captopril on urinary excretion of albumin and prostaglandins in patients with diabetic nephropathy.Diabetes research (Edinburgh, Scotland), , Volume: 13, Issue:3, 1990
Comparative efficacy of dietary treatments on renal function in rats with sub-total nephrectomy: renal polyunsaturated fatty acid incorporation and prostaglandin excretion.Clinical nephrology, , Volume: 33, Issue:1, 1990
Evidence against a role for prostaglandins in sustaining renal hyperfiltration in type 1 diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association, , Volume: 6, Issue:6, 1989
Prostaglandins and diabetic nephropathy.Journal of diabetes and its complications, , Volume: 9, Issue:4
Effects of cilostazol, a phosphodiesterase inhibitor, on urinary excretion of albumin and prostaglandins in non-insulin-dependent diabetic patients.Diabetes research and clinical practice, , Volume: 22, Issue:1
Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day.Alcoholism, clinical and experimental research, , Volume: 32, Issue:11, 2008
Alcohol and coronary spasm.Angiology, , Volume: 45, Issue:3, 1994
Type A behavior and alcohol consumption: effects on resting and post-exercise bleeding time thromboxane and prostacyclin metabolites.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 48, Issue:2, 1993
Effect of acute ethanol ingestion on human gastric luminal prostaglandin E2, prostaglandin F2 alpha and 6-keto-prostaglandin F1 alpha.Alcohol and alcoholism (Oxford, Oxfordshire), , Volume: 24, Issue:1, 1989
Relationship between ethanol, HDL, and vascular prostacyclin production.Transactions of the Association of American Physicians, , Volume: 100, 1987
Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects.Obstetrics and gynecology, , Volume: 71, Issue:1, 1988
GC/MS assay of prostaglandins in cerebrospinal fluid from humans and monkeys.Advances in alcohol & substance abuse, , Volume: 7, Issue:3-4, 1988
Decreased systemic formation of prostaglandin E and prostacyclin, and unchanged thromboxane formation, in alcoholics during withdrawal as estimated from metabolites in urine.Clinical science (London, England : 1979), , Volume: 73, Issue:3, 1987
Relationship between ethanol, HDL, and vascular prostacyclin production.Transactions of the Association of American Physicians, , Volume: 100, 1987
Urinary excretion of 2, 3-dinor-6-keto prostaglandin F1 alpha and platelet thromboxane formation during ethanol withdrawal in alcoholics.Journal of clinical pathology, , Volume: 40, Issue:5, 1987
[The effect of inhaled nitric oxide on endothelium-derived angiokinetic factors in patients with acute high altitude disease].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 30, Issue:2, 2007
Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 67, Issue:5, 1989
Release of calcitonin gene-related peptide in cardiac anaphylaxis.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 355, Issue:2, 1997
Relevance of mediators to cardiac parameters of isolated anaphylactic guinea-pig heart.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:1, 1995
Effect of 3-morpholinosydnonimine (SIN-1) and NG-nitro-L-arginine (NNA) on isolated perfused anaphylactic guinea-pig hearts.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 345, Issue:1, 1992
The effect of three novel thromboxane A2 receptor antagonists (S-1452, AA-2414 and ONO-3708) on the increase in pulmonary pressure caused by Forssman anaphylaxis in guinea-pigs.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:3, 1992
Leukotrienes, thromboxane A2, and prostaglandins during systemic anaphylaxis in sheep.The American journal of physiology, , Volume: 261, Issue:3 Pt 2, 1991
OKY-046 inhibits anaphylactic bronchoconstriction and reduces histamine level in bronchoalveolar lavage fluid in sensitized guinea pigs.Prostaglandins, , Volume: 39, Issue:6, 1990
Inhibition of the release of prostaglandins, thromboxanes, and leukotrienes from anaphylactic lungs by a platelet-activating factor (PAF) antagonist and its stimulation by PAF.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 17B, 1987
Effect of exogenous 5,8,11,14,17-eicosapentaenoic acid on cardiac anaphylaxis.British journal of pharmacology, , Volume: 90, Issue:2, 1987
Cyclooxygenase blockade elevates leukotriene E4 production during acute anaphylaxis in sheep.The Journal of experimental medicine, , Jun-01, Volume: 163, Issue:6, 1986
Modulation of eicosanoid release from anaphylactic guinea-pig heart with 5-benzoyl-a-methyl-2-thiophene acetic acid (tiaprofenic acid).Archives internationales de pharmacodynamie et de therapie, , Volume: 278, Issue:2, 1985
Eicosanoids, leukocytes and lung injury.Progress in clinical and biological research, , Volume: 199, 1985
Effects of exogenous prostaglandins on the release of leukotriene C4-like immunoreactivity and on coronary flow in indomethacin-treated anaphylactic guinea-pig hearts.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 326, Issue:4, 1984
Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis.British journal of pharmacology, , Volume: 80, Issue:1, 1983
Prostacyclin, thromboxane and glomerular filtration rate are abnormal in sickle cell pregnancy.PloS one, , Volume: 12, Issue:9, 2017
Sickle erythrocytes increase prostacyclin and endothelin-1 production by cultured human endothelial cells under flow conditions.European journal of haematology, , Volume: 68, Issue:3, 2002
Sickle cell vaso-occlusive crisis is associated with abnormalities in the ratio of vasoconstrictor to vasodilator prostanoids.Pediatric research, , Volume: 38, Issue:1, 1995
Elevated urinary levels of thromboxane and prostacyclin metabolities in sickle cell disease reflects activated platelets in the circulation.British journal of haematology, , Volume: 87, Issue:3, 1994
Increased in vivo production of thromboxane in patients with sickle cell disease is accompanied by an impairment of platelet functions to the thromboxane A2 agonist U46619.Arteriosclerosis and thrombosis : a journal of vascular biology, , Volume: 13, Issue:3, 1993
Effects of normal and sickle erythrocytes on prostacyclin release by perfused human umbilical cord veins.American journal of hematology, , Volume: 40, Issue:4, 1992
Modification of membrane properties of erythrocytes by PGI2.Thrombosis research, , Jun-15, Volume: 54, Issue:6, 1989
Decreased prostacyclin levels in sickle-cell disease.Pediatric hematology and oncology, , Volume: 6, Issue:1, 1989
Release of prostacyclin after erythrocyte adhesion to cultured vascular endothelium.The Journal of laboratory and clinical medicine, , Volume: 107, Issue:3, 1986
Decreased prostacyclin levels in sickle cell disease.Pediatrics, , Volume: 71, Issue:5, 1983
Prostacyclin and platelet aggregation in sickle cell disease.Pediatrics, , Volume: 70, Issue:3, 1982
Laser speckle contrast imaging for quantitative assessment of facial flushing during mesenteric traction syndrome in upper gastrointestinal surgery.Journal of clinical monitoring and computing, , Volume: 33, Issue:5, 2019
Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 282, Issue:4, 2002
Adaptive cytoprotection mediated by prostaglandin I(2) is attributable to sensitization of CRGP-containing sensory nerves.Gastroenterology, , Volume: 120, Issue:1, 2001
Anti-inflammatory activity of macrolide antibiotics.The Journal of pharmacology and experimental therapeutics, , Volume: 292, Issue:1, 2000
Intravenous aspirin at reperfusion does not reduce infarct size in the dog with a residual critical stenosis.Journal of cardiovascular pharmacology, , Volume: 34, Issue:4, 1999
Effect of fluoride on cardiopulmonary function and release of eicosanoids in pigs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 78, Issue:2, 1995
Prostacyclin mediates antiaggregatory and hypotensive actions of endothelin in anaesthetized beagle dogs.British journal of pharmacology, , Volume: 98, Issue:1, 1989
Effects of recombinant human tumor necrosis factor alpha, lymphotoxin, and Escherichia coli lipopolysaccharide on hemodynamics, lung microvascular permeability, and eicosanoid synthesis in anesthetized sheep.Circulation research, , Volume: 65, Issue:2, 1989
Direct and indirect effects of leukotriene D4 on the lungs of unanesthetized sheep.Respiration; international review of thoracic diseases, , Volume: 51, Issue:4, 1987
Effects of halothane and enflurane on prostanoid concentrations in operation patients.Prostaglandins, leukotrienes, and medicine, , Volume: 29, Issue:1, 1987
The immediate effect of burn wound excision on pulmonary function in sheep: the role of prostanoids, oxygen radicals, and chemoattractants.Surgery, , Volume: 101, Issue:1, 1987
Effect of thromboxane synthetase inhibitors (OKY-046, OKY-1580) on experimentally induced air embolism in anesthetized dogs.Prostaglandins, leukotrienes, and medicine, , Volume: 21, Issue:2, 1986
Action of arachidonic acid in ureteral-ligated kidney of the anesthetized canine: possible lipoxygenase activity.Canadian journal of physiology and pharmacology, , Volume: 62, Issue:6, 1984
Prostanoids and hemodynamics in man before and during cardiopulmonary bypass.Prostaglandins, , Volume: 28, Issue:4, 1984
The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds.Journal of molecular and cellular cardiology, , Volume: 16, Issue:1, 1984
Effects of anesthesia and surgery on prostanoid concentrations in plasma and pulmonary lymph.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:2, 1983
Bronchodilator effects of prostacyclin (PGI2) in dogs and guinea pigs.European journal of pharmacology, , Aug-22, Volume: 66, Issue:1, 1980
Enhanced external counterpulsation improves peripheral artery flow-mediated dilation in patients with chronic angina: a randomized sham-controlled study.Circulation, , Oct-19, Volume: 122, Issue:16, 2010
Increased serotonin release across the coronary bed during a nonischemic interval in patients with vasospastic angina.Clinical cardiology, , Volume: 19, Issue:6, 1996
The effect of caffeine on prostaglandin output from the perfused mesenteric vascular bed of the rat.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:6, 1994
Eicosanoid biosynthesis in patients with stable angina: beneficial effects of very low dose aspirin.Journal of the American College of Cardiology, , Volume: 24, Issue:1, 1994
Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction.The American journal of cardiology, , Jun-01, Volume: 73, Issue:15, 1994
The effects of orally administered atenolol on the coronary hemodynamics and prostaglandin metabolism in angina pectoris patients.Angiology, , Volume: 45, Issue:3, 1994
Effect of diltiazem on silent ischemic episodes, plasma bradykinin and prostaglandin metabolism.International journal of cardiology, , Volume: 37, Issue:2, 1992
[Clinical study in treating qi-deficiency and blood-stasis syndrome of angina pectoris with qi xue granule].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 12, Issue:11, 1992
Inhibition of platelet aggregation by prostacyclin is attenuated after exercise in patients with angina pectoris.American heart journal, , Volume: 123, Issue:2, 1992
[Relation of coronary heart disease based on traditional Chinese medicine syndrome differentiation and prostaglandin, blood platelet function, and protein C].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:5, 1991
[Anti-angina effect of puerarin and its effect on plasma thromboxane A2 and prostacyclin].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:2, 1990
[Effects of Codonopsis pilosulae on the synthesis of thromboxane A2 and prostacyclin].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:7, 1990
Prostaglandin I2 half-life regulated by high density lipoprotein is decreased in acute myocardial infarction and unstable angina pectoris.Circulation, , Volume: 81, Issue:6, 1990
Hemodynamic, platelet and clinical responses to prostacyclin in unstable angina pectoris.The American journal of cardiology, , May-01, Volume: 65, Issue:16, 1990
[Effect of a single episode of exertion on serum 6-keto-PGF1 alpha concentration in healthy individuals and patients with exercise-induced stable angina pectoris].Polski tygodnik lekarski (Warsaw, Poland : 1960), , Jun-05, Volume: 44, Issue:23, 1989
Plasma bradykinin and prostaglandin metabolism and exercise testing in patients with silent myocardial ischemia compared with patients with painful myocardial ischemia.Japanese circulation journal, , Volume: 53, Issue:11, 1989
[Platelet functions in patients with acute myocardial infarction].Zhonghua xin xue guan bing za zhi, , Volume: 17, Issue:5, 1989
Radioimmunoassay of thromboxane B2 and its preliminary applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:1, 1988
[Newly developed stenocardia: functional activity of thrombocytes].Kardiologiia, , Volume: 28, Issue:7, 1988
[A clinical trial of sheng-mai liquor in the treatment of ischemic heart disease].Zhonghua xin xue guan bing za zhi, , Volume: 15, Issue:3, 1987
Biochemical evidence of platelet activation in patients with persistent unstable angina.Journal of the American College of Cardiology, , Volume: 10, Issue:5, 1987
Effects of a selective thromboxane synthetase inhibitor (OKY-046) in patients with coronary artery disease during exercise.Japanese heart journal, , Volume: 28, Issue:5, 1987
Effects of iloprost (ZK 36374), a prostacyclin derivative, on platelet function after ischaemic exercise in patients with stable angina pectoris.Thrombosis research, , Oct-15, Volume: 48, Issue:2, 1987
Fibrinopeptide A and platelet factor levels in unstable angina pectoris.Circulation, , Volume: 75, Issue:1, 1987
Myocardial ischaemia triggers formation of thromboxane.Lancet (London, England), , Sep-05, Volume: 2, Issue:8558, 1987
[Clinical and experimental study on the treatment of angina pectoris with kuo guan granules].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 7, Issue:6, 1987
[Unstable stenocardia: functional activity and free cytoplasmic calcium of thrombocytes and vaso- and thrombocytoactive prostanoids].Kardiologiia, , Volume: 27, Issue:10, 1987
[Hemodynamic effects of nitroglycerin following acute inhibition of prostaglandin synthesis].Zeitschrift fur Kardiologie, , Volume: 75, Issue:11, 1986
Impaired cardiac PGI2 and PGE2 biosynthesis in patients with angina pectoris.American heart journal, , Volume: 112, Issue:3, 1986
[Thromboxane and prostacyclin in patients with stenocardia in induced and spontaneous ischemia of the myocardium].Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, , Volume: 9, Issue:1, 1986
Platelet activation in unstable coronary disease.The New England journal of medicine, , Oct-16, Volume: 315, Issue:16, 1986
Coronary spasm, prostaglandin and HLA factors.Japanese circulation journal, , Volume: 49, Issue:1, 1985
Development of quantitative analysis of plasma thromboxane B2 by gas chromatography-mass spectrometry.Japanese circulation journal, , Volume: 49, Issue:3, 1985
Effects of selective thromboxane synthetase inhibitor OKY-046 on plasma prostaglandins in patients with coronary artery disease during exercise.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Cardiac prostaglandin synthesis in spontaneous and in effort angina.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
The effects of organic nitrates on prostacyclin biosynthesis and platelet function in humans.Circulation, , Volume: 70, Issue:2, 1984
Hemodynamic effects of intravenous prostacyclin in stable angina pectoris.The American journal of cardiology, , Sep-01, Volume: 52, Issue:5, 1983
[Biochemistry of coronary artery disease--prostaglandins].Rinsho byori. The Japanese journal of clinical pathology, , Volume: 31, Issue:8, 1983
Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease.The New England journal of medicine, , Mar-19, Volume: 304, Issue:12, 1981
Coronary spasm, prostaglandin and HLA factors.Japanese circulation journal, , Volume: 49, Issue:1, 1985
Prostacyclin and variant angina.Annals of the New York Academy of Sciences, , Volume: 454, 1985
[Plasma levels of thromboxane B2 and 6-keto PGF1 alpha in patients with variant angina].Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, , Volume: 74, Issue:6, 1985
Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 24, Issue:4, 2004
Transcardiac 5-hydroxytryptamine release and impaired coronary endothelial function in patients with vasospastic angina.Clinical and experimental pharmacology & physiology, , Volume: 25, Issue:12, 1998
Prostaglandin I2 half-life regulated by high density lipoprotein is decreased in acute myocardial infarction and unstable angina pectoris.Circulation, , Volume: 81, Issue:6, 1990
Hemodynamic, platelet and clinical responses to prostacyclin in unstable angina pectoris.The American journal of cardiology, , May-01, Volume: 65, Issue:16, 1990
[Platelet functions in patients with acute myocardial infarction].Zhonghua xin xue guan bing za zhi, , Volume: 17, Issue:5, 1989
[Newly developed stenocardia: functional activity of thrombocytes].Kardiologiia, , Volume: 28, Issue:7, 1988
Biochemical evidence of platelet activation in patients with persistent unstable angina.Journal of the American College of Cardiology, , Volume: 10, Issue:5, 1987
Fibrinopeptide A and platelet factor levels in unstable angina pectoris.Circulation, , Volume: 75, Issue:1, 1987
[Unstable stenocardia: functional activity and free cytoplasmic calcium of thrombocytes and vaso- and thrombocytoactive prostanoids].Kardiologiia, , Volume: 27, Issue:10, 1987
Platelet activation in unstable coronary disease.The New England journal of medicine, , Oct-16, Volume: 315, Issue:16, 1986
Impaired cardiac PGI2 and PGE2 biosynthesis in patients with angina pectoris.American heart journal, , Volume: 112, Issue:3, 1986
[Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 25, Issue:1, 2009
AAV-PGIS gene transfer improves hypoxia-induced pulmonary hypertension in mice.Biochemical and biophysical research communications, , Nov-23, Volume: 363, Issue:3, 2007
Effect of Ibuprofen on interleukin-1beta-induced abnormalities in hemodynamics and oxygen metabolism in rabbits.Shock (Augusta, Ga.), , Volume: 20, Issue:6, 2003
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs.American journal of physiology. Lung cellular and molecular physiology, , Volume: 284, Issue:2, 2003
[Effect of aspirin on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 19, Issue:4, 2003
Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension.Cardiovascular research, , Volume: 55, Issue:1, 2002
Integration of hypoxic dilation signaling pathways for skeletal muscle resistance arteries.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 283, Issue:2, 2002
Hypoxic induction of cox-2 regulates proliferation of human pulmonary artery smooth muscle cells.American journal of respiratory cell and molecular biology, , Volume: 27, Issue:6, 2002
Exaggerated hypoxic pulmonary hypertension in endothelin B receptor-deficient rats.American journal of physiology. Lung cellular and molecular physiology, , Volume: 282, Issue:4, 2002
Factors that increase the contractile tone of the ductus arteriosus also regulate its anatomic remodeling.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 281, Issue:1, 2001
Dose-response to inhaled aerosolized prostacyclin for hypoxemia due to ARDS.Chest, , Volume: 117, Issue:3, 2000
Effects of prostaglandins and leukotrienes on hypoxic pulmonary vasoconstriction in rats.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 20, Issue:3, 2000
Prostanoids: early mediators in the secondary injury that develops after unilateral pulmonary contusion.The Journal of trauma, , Volume: 46, Issue:5, 1999
Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats.Anesthesia and analgesia, , Volume: 89, Issue:4, 1999
Response of intra-acinar pulmonary microvessels to hypoxia, hypercapnic acidosis, and isocapnic acidosis.Circulation research, , Apr-06, Volume: 82, Issue:6, 1998
Activated endothelial cells elicit paracrine induction of epithelial chloride secretion. 6-Keto-PGF1alpha is an epithelial secretagogue.The Journal of clinical investigation, , Sep-15, Volume: 102, Issue:6, 1998
Cerebral arteriolar dilation to hypoxia: role of prostanoids.The American journal of physiology, , Volume: 272, Issue:1 Pt 2, 1997
Effects of tetramethylpyrazine on the release of PGI2 and TXA2 in the hypoxic isolated rat heart.Molecular and cellular biochemistry, , Volume: 167, Issue:1-2, 1997
Systemic levels of 6-keto-prostaglandin F1 alpha following administration of inhaled aerosolized prostacyclin.Anaesthesia and intensive care, , Volume: 25, Issue:6, 1997
Oxygen deprivation and reoxygenation augment prostacyclin synthesis in cultured ventricular myocytes.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 54, Issue:3, 1996
NMDA receptors mediate anoxia/aglycemia-induced release of eicosanoids in immature rat hippocampal slices: utility of an in vitro "ischemic" superfusion model with temporary arrest of medium flow.Folia neuropathologica, , Volume: 32, Issue:3, 1994
Effects of hypoxia on platelet activation in pilots.Aviation, space, and environmental medicine, , Volume: 65, Issue:7, 1994
Prostanoid production in hypoxic rat isolated atria: influence of acute diabetes.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:4, 1994
Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine.Shock (Augusta, Ga.), , Volume: 2, Issue:5, 1994
Some humoral factors and their interaction on acute hypoxic pulmonary pressor response.Chinese medical journal, , Volume: 107, Issue:2, 1994
Endothelium-dependent response of human internal mammary artery to hypoxia.The American journal of physiology, , Volume: 264, Issue:2 Pt 2, 1993
Alteration in hypoxic pulmonary vasoconstriction during hypothermia in dogs.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:3, 1992
Relation between arterial hypoxemia and plasma eicosanoids in neonates with congenital diaphragmatic hernia.The Journal of surgical research, , Volume: 53, Issue:6, 1992
Cellular mechanisms that control pulmonary vascular tone during hypoxia and normoxia. Possible role of Ca2+ATPases.The American review of respiratory disease, , Volume: 145, Issue:6, 1992
[Plasma renin activity, angiotensin II, angiotensin converting enzyme, thromboxane A2 and prostacyclin I2 levels in pigs with severe hypoxia and hypercapnea and acidosis shock].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 15, Issue:1, 1992
Effect of endotoxin on hypoxic pulmonary vasoconstriction--the role of prostaglandins and leukotrienes.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:1, 1992
Hypoxia inhibits renal thromboxane and not prostacyclin release.Circulatory shock, , Volume: 33, Issue:4, 1991
Leukotrienes and prostaglandins in fetal lung liquid.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 68, Issue:5, 1990
The effect of hypoxia on angiotensin-stimulated release of PGI2 from the splanchnic bed.The Journal of trauma, , Volume: 30, Issue:8, 1990
Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 67, Issue:5, 1989
Relation of TXA2 and PGI2 to the difference in hypoxic pulmonary vasoconstriction between different strains of rats.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 9, Issue:3, 1989
Effects of cigarette smoking on hemodynamics and hypoxic pulmonary vasoconstriction: role of prostaglandins and leukotrienes.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 9, Issue:4, 1989
The effect of hypoxia on rat splanchnic prostanoid output.Prostaglandins, , Volume: 38, Issue:5, 1989
Prostacyclin contributes to inhibition of hypoxic pulmonary vasoconstriction by alkalosis.Prostaglandins, , Volume: 38, Issue:1, 1989
Release of thromboxane A2 by low-dose almitrine in the hypoxic dog.The European respiratory journal, , Volume: 1, Issue:8, 1988
The carbochromene derivative AD6 reduces the TxB2/6-keto-PGF1 alpha ratio in cerebral cortex during hypoxia and recovery and leukotriene synthesis in brain tissue, in the rat.Prostaglandins, , Volume: 35, Issue:1, 1988
Age-dependent effects of indomethacin on hypoxic vasoconstriction in neonatal lamb lungs.Pediatric research, , Volume: 23, Issue:6, 1988
Experimental studies on pulmonary vascular response to alveolar hypoxia during almitrine infusion in anesthetized dogs.Hiroshima journal of medical sciences, , Volume: 36, Issue:4, 1987
Synthesis of prostaglandins, TXA2 and PGI2, during one lung anesthesia.Prostaglandins, , Volume: 34, Issue:5, 1987
Role of eicosanoids in hypoxic vasoconstriction in isolated lamb lungs.The American journal of physiology, , Volume: 253, Issue:3 Pt 2, 1987
Thromboxane as a mediator of pulmonary dysfunction during intravascular complement activation in sheep.The American review of respiratory disease, , Volume: 133, Issue:2, 1986
Mediator release from human lung under conditions of reduced oxygen tension.The Journal of pharmacology and experimental therapeutics, , Volume: 238, Issue:1, 1986
Thromboxane A2 and prostacyclin do not modulate pulmonary hemodynamics during exercise in sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 61, Issue:5, 1986
Effects of verapamil on thromboxane synthesis and pulmonary hypertension in sheep.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 9, Issue:3, 1986
Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:4, 1986
Effects of indomethacin on estradiol-induced attenuation of hypoxic vasoconstriction in lamb lungs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 61, Issue:6, 1986
Effects of hypoxia and anoxia on the ex vivo release of prostaglandins from mouse cortical slices.Journal of neurochemistry, , Volume: 47, Issue:6, 1986
Effect of hypoxia on prostacyclin production in cultured pulmonary artery endothelium.Prostaglandins, , Volume: 31, Issue:6, 1986
Relation of prostanoids to strength of hypoxic vasoconstriction in dogs with lobar atelectasis.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 59, Issue:1, 1985
Prostaglandins and estradiol-induced attenuation of hypoxic pulmonary vasoconstriction.Chest, , Volume: 88, Issue:4 Suppl, 1985
Pulmonary dysfunction secondary to soft-tissue endotoxin.Archives of surgery (Chicago, Ill. : 1960), , Volume: 120, Issue:2, 1985
Effects of high frequency oscillatory ventilation compared to conventional ventilation upon pulmonary vascular prostanoid production in neonatal piglets.Prostaglandins, leukotrienes, and medicine, , Volume: 17, Issue:1, 1985
Hypoxia enhances prostaglandin synthesis in renal mesangial cell cultures.Prostaglandins, , Volume: 30, Issue:1, 1985
The role of prostacyclin in the hypercapnic and hypoxic cerebrovascular dilations.Life sciences, , May-07, Volume: 34, Issue:19, 1984
Failure of acute hypoxia to alter pulmonary prostaglandin metabolism in dogs.Prostaglandins, , Volume: 25, Issue:5, 1983
Effect of cholesterol feeding and gender on the response of the isolated rat heart to hypoxia.Canadian journal of physiology and pharmacology, , Volume: 60, Issue:12, 1982
Thromboxane and prostacyclin (epoprostenol) during exercise in diffuse pulmonary fibrosis.Lancet (London, England), , Nov-27, Volume: 2, Issue:8309, 1982
Hypoxia stimulates prostacyclin generation by dog lung in vitro.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:4, 1982
[Effect of hypoxemia and pulmonary thromboembolism on plasma levels of 6-keto PGF 1 alpha, TxB, histamine and serotonin in anesthetized dogs (author's transl)].Nihon Kyobu Shikkan Gakkai zasshi, , Volume: 19, Issue:8, 1981
Developmental changes in synthesis of and responsiveness to prostaglandins I2 and E2 in hypoxic lamb lungs.Canadian journal of physiology and pharmacology, , Volume: 76, Issue:7-8
[Prostaglandins content in the blood of newborns with various types of hypoxia].Fiziologicheskii zhurnal, , Volume: 39, Issue:2-3
Estrogen modulates permeability and prostaglandin levels in the rabbit urinary bladder.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 80, Issue:2-3
The role of prostacyclin in the mesenteric traction syndrome during anesthesia for abdominal aortic reconstructive surgery.Annals of surgery, , Volume: 209, Issue:3, 1989
Synthetic arterial grafts cause prolonged increase in the in vivo formation of thromboxane and prostacyclin in humans.Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, , Volume: 187, Issue:3, 1987
Maintenance of cardiodynamics with aspirin during abdominal aortic aneurysmectomy (AAA).Annals of surgery, , Volume: 194, Issue:5, 1981
Plasma CPU-86017 concentrations regarding suppression of ouabain-induced cardiac arrhythmias and decrease of heart rate in guinea pigs.Acta pharmacologica Sinica, , Volume: 21, Issue:11, 2000
Effects of the new class I antiarrhythmic agent Ro 22-9194, (2R)-2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide D-tartrate, on ischemia- and reperfusion-induced arrhythmias in dogs: involvement of thromboxane A2 synthase inhibitory actThe Journal of pharmacology and experimental therapeutics, , Volume: 279, Issue:2, 1996
Effect of aspirin treatment on plasma levels of keto PGF 1 alpha and thromboxane B2.The Journal of the Association of Physicians of India, , Volume: 43, Issue:9, 1995
Changes in 6 keto PGF1 alpha and TXB2 in patients with myocardial infarction.The Journal of the Association of Physicians of India, , Volume: 42, Issue:2, 1994
Effects of quercetin on platelet and reperfusion-induced arrhythmias in rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 14, Issue:6, 1993
Effect of ubiquinone on ischemic arrhythmia in conscious rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 12, Issue:3, 1991
Effect of cicletanine on reperfusion-induced arrhythmias and its relation to 6-keto-PGF1 alpha and thromboxane B2 release.Canadian journal of physiology and pharmacology, , Volume: 69, Issue:4, 1991
Occlusion and reperfusion-induced arrhythmias in rats: involvement of platelets and effects of calcium antagonists.Journal of cardiovascular pharmacology, , Volume: 15, Issue:5, 1990
Effects of cicletanine in the left circumflex coronary artery occlusion-reperfusion canine model of sudden death: analysis of 107 experiments using Cox's proportional hazards model.Drugs under experimental and clinical research, , Volume: 14, Issue:2-3, 1988
Role of prostaglandins in the arrhythmogenic effects of ouabain on isolated guinea pig hearts.European journal of pharmacology, , Sep-23, Volume: 141, Issue:3, 1987
A possible role for endogenous prostaglandins in the electrophysiological effects of acetylstrophanthidin on isolated canine ventricular tissues.Circulation research, , Volume: 58, Issue:4, 1986
[Antagonism of collagen-induced ECG changes in rats by a thromboxane synthetase inhibitor, CV-4151].Nihon yakurigaku zasshi. Folia pharmacologica Japonica, , Volume: 87, Issue:4, 1986
Follow-up of prostaglandin plasma levels after acute myocardial infarction.American heart journal, , Volume: 109, Issue:2, 1985
Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain.The American journal of physiology, , Volume: 249, Issue:1 Pt 2, 1985
Further evidence that thromboxane exacerbates arrhythmias: effects of UK38485 during coronary artery occlusion and reperfusion in anaesthetized greyhounds.Journal of molecular and cellular cardiology, , Volume: 16, Issue:7, 1984
The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds.Journal of molecular and cellular cardiology, , Volume: 16, Issue:1, 1984
The effects of timolol on arrhythmias and prostanoid release during canine myocardial ischaemia and reperfusion.British journal of pharmacology, , Volume: 81, Issue:4, 1984
Prostaglandins and the antiarrhythmic effect of preconditioning in the isolated rat heart.Molecular and cellular biochemistry, , Volume: 160-161
The effects of dietary mackerel oil on plasma and cell membrane lipids, on hemodynamics and cardiac arrhythmias during recurrent acute ischemia in the pig.Basic research in cardiology, , Volume: 81, Issue:6
[Relationship between syndrome differentiation of traditional Chinese medicine and vascular endothelial function in patients with diabetic arterial occlusion of lower extremities].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 5, Issue:6, 2007
Catheter-based prostacyclin synthase gene transfer prevents in-stent restenosis in rabbit atheromatous arteries.Cardiovascular research, , Jan-01, Volume: 61, Issue:1, 2004
Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 65, Issue:4, 2001
Reduction by indobufen of neutrophil activation in peripheral arterial occlusive disease.Journal of cardiovascular pharmacology, , Volume: 27, Issue:3, 1996
Beneficial effects of BAY u3405, a novel thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock.Pharmacology, , Volume: 49, Issue:6, 1994
Protective effects of G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock.Journal of cardiovascular pharmacology, , Volume: 19, Issue:1, 1992
Platelet activating factor involvement in splanchnic artery occlusion shock in rats.European journal of pharmacology, , Jan-03, Volume: 192, Issue:1, 1991
Intramuscular accumulation of prostaglandins during static contraction of the cat triceps surae.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 71, Issue:5, 1991
Occlusion and reperfusion-induced arrhythmias in rats: involvement of platelets and effects of calcium antagonists.Journal of cardiovascular pharmacology, , Volume: 15, Issue:5, 1990
Interleukin 1 enhances arterial thrombogenicity in vitro.Thrombosis research, , Nov-15, Volume: 56, Issue:4, 1989
Influence of coronary artery obstruction on cardiac prostaglandin metabolism during experimental cardioplegic arrest.The Thoracic and cardiovascular surgeon, , Volume: 34, Issue:2, 1986
Thromboxane release during percutaneous transluminal coronary angioplasty.American heart journal, , Volume: 111, Issue:1, 1986
Pentoxifylline treatment in patients with occlusive peripheral arterial disease. Circulatory changes and effects on prostaglandin synthesis.Angiology, , Volume: 36, Issue:9, 1985
Regulation of increase in anastomotic blood flow following pulmonary arterial occlusion.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 59, Issue:1, 1985
Prostacyclin synthesis by proliferative aortic smooth muscle cells.VASA. Zeitschrift fur Gefasskrankheiten, , Volume: 13, Issue:4, 1984
Prostacyclin and blood glucose levels in humans and rabbits.Prostaglandins, , Volume: 21, Issue:1, 1981
Do alterations in prostanoid or catecholamine release influence the antiarrhythmic activity of nicergoline?Journal of cardiovascular pharmacology, , Volume: 8, Issue:2
Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites.Journal of the American College of Nutrition, , Volume: 26, Issue:5, 2007
[Prostacyclin and their metabolites].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 63 Suppl 8, 2005
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins.Circulation research, , Mar-19, Volume: 94, Issue:5, 2004
Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men.Biomedical and environmental sciences : BES, , Volume: 16, Issue:4, 2003
A clinical and experimental study on the protective effects of jiangzhi tongmai fang on endothelial injury.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 22, Issue:2, 2002
The combined use of prostaglandin I2 analogue (OP-2507) and thromboxane A2 synthetase inhibitor (OKY-046) strongly inhibits atherosclerosis of aortic allografts in rats.Surgery, , Volume: 129, Issue:5, 2001
6-oxo-PGF(1 alpha)and 8-epi-PGF(2 alpha)in the arterial wall layers of various species: a comparison between intact and atherosclerotic areas.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 64, Issue:3, 2001
Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis.Circulation, , Aug-22, Volume: 102, Issue:8, 2000
Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol.Thrombosis research, , Nov-15, Volume: 100, Issue:4, 2000
[Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension].Terapevticheskii arkhiv, , Volume: 72, Issue:4, 2000
Defibrotide normalizes cardiovascular function hampered by established atherosclerosis in the rabbit.Thrombosis research, , Jan-15, Volume: 97, Issue:2, 2000
6-Oxo-PGF1alpha and 8-epi-PGF2alpha in human atherosclerotic vascular tissue.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 60, Issue:2, 1999
Coronary constriction and consequent cardiodepression in pulmonary embolism are mediated by pulmonary big endothelin and enhanced in early endothelial dysfunction.Critical care medicine, , Volume: 26, Issue:3, 1998
[Experimental study on anti-atherosclerotic effect of tongmai jiangzhi oral liquor].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:8, 1995
Low-dose aspirin does not attenuate platelet aggregation or atherosclerosis in miniature swine but decreases production of aortic wall prostacyclin.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:5, 1995
[The experimental observation on the procedure of atherosclerotic restenosis following PTCA].Zhonghua nei ke za zhi, , Volume: 34, Issue:8, 1995
Monocyte chemoattractant protein 1 inhibits growth of rat vascular smooth muscle cells.The American journal of physiology, , Volume: 268, Issue:3 Pt 2, 1995
Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:5, 1994
Prostacyclin, thromboxane A2, and atherosclerosis in young hypercholesterolemic swine.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:4, 1994
Prostanoid release immediately after balloon angioplasty in three models of atherosclerosis in rabbits.The European journal of surgery = Acta chirurgica, , Volume: 159, Issue:1, 1993
[Experimental study of atherosclerosis and cholelithiasis with the same treatment. I. Effects of yiqi huoxue and shugan liqi agents in atherosclerosis of rabbit].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 12, Issue:7, 1992
Low level of prostacyclin as a risk of ischaemic heart disease.International journal of cardiology, , Volume: 30, Issue:2, 1991
Spontaneous atherosclerotic lesions and prostacyclin formation in rabbits: effects of combined dipyridamole and aspirin.Biomedica biochimica acta, , Volume: 48, Issue:9, 1989
Thromboxane A2 and prostacyclin generation in the microvasculature of patients with atherosclerosis--effect of low-dose aspirin.Thrombosis and haemostasis, , Jun-30, Volume: 61, Issue:3, 1989
[Plasma and cellular factors of atherogenesis and the prostanoid system at the early stages of arterial hypertension].Kardiologiia, , Volume: 29, Issue:9, 1989
Individually controlled acetylsalicyclic acid (ASA) in the long-term treatment of patients with arteriosclerosis.Biomedica biochimica acta, , Volume: 47, Issue:10-11, 1988
Clinical effectiveness of defibrotide in vaso-occlusive disorders and its mode of actions.Seminars in thrombosis and hemostasis, , Volume: 14 Suppl, 1988
Vasoactive and atherogenic effects of cigarette smoking: a study of monozygotic twins discordant for smoking.BMJ (Clinical research ed.), , Oct-15, Volume: 297, Issue:6654, 1988
Effects of cardiopulmonary bypass on pulmonary leukostasis and complement activation.Archives of surgery (Chicago, Ill. : 1960), , Volume: 123, Issue:12, 1988
Leg exercise increases prostacyclin synthesis without activating platelets in both healthy and atherosclerotic humans.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 17A, 1987
Influence of atherosclerosis on vascular responsiveness in isolated rabbit vascular smooth muscle.Cardiovascular drugs and therapy, , Volume: 1, Issue:4, 1987
Plasma thromboxane and prostacyclin metabolite ratio in atherosclerosis and diabetes mellitus.Thrombosis research, , Aug-15, Volume: 47, Issue:4, 1987
Increased aortic thromboxane production in experimental atherosclerosis.Prostaglandins, leukotrienes, and medicine, , Volume: 29, Issue:1, 1987
Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase.Circulation, , Volume: 73, Issue:6, 1986
Molecular markers of hemostatic activation in atherosclerosis: a new concept in diagnostic profiling of endogenous pathophysiologic transition.Seminars in thrombosis and hemostasis, , Volume: 12, Issue:2, 1986
Platelet hyperaggregability, blood prostacyclin and dipyridamole.Angiology, , Volume: 37, Issue:3 Pt 1, 1986
In vivo effects of defibrotide on platelet c-AMP and blood prostanoid levels.Haemostasis, , Volume: 16 Suppl 1, 1986
In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis.The New England journal of medicine, , Apr-10, Volume: 314, Issue:15, 1986
Effect of glucocorticoid administration early in life on aortic prostaglandin synthesis and morphology in atherosclerosis-susceptible pigeons.Experimental and clinical endocrinology, , Volume: 85, Issue:2, 1985
Alteration of prostanoids in atherosclerosis.Seminars in thrombosis and hemostasis, , Volume: 11, Issue:4, 1985
[Activity of ticlopidine and lysine acetylsalicylate in experimental atheromatosis. Effects on the production of PGI2].Archivos de farmacologia y toxicologia, , Volume: 11, Issue:2, 1985
Prostacyclin and variant angina.Annals of the New York Academy of Sciences, , Volume: 454, 1985
Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors.Circulation, , Volume: 72, Issue:2, 1985
Prostaglandins and cyclic nucleotides. Modulators of arterial cholesterol metabolism.Biochemical pharmacology, , Feb-01, Volume: 34, Issue:3, 1985
[Pathogenetic importance of prostacyclin in atherosclerosis].Terapevticheskii arkhiv, , Volume: 57, Issue:9, 1985
Increased prostacyclin biosynthesis in patients with severe atherosclerosis and platelet activation.The New England journal of medicine, , Apr-26, Volume: 310, Issue:17, 1984
Cyclic nucleotides, prostaglandins, and ischemic heart disease.Advances in cyclic nucleotide and protein phosphorylation research, , Volume: 17, 1984
Prostaglandins modulate arterial cholesteryl ester metabolism.Enzyme, , Volume: 32, Issue:4, 1984
Prostacyclin formation by human aorta in different types of atherosclerotic lesion.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
Prostacyclin synthesis by proliferative aortic smooth muscle cells.VASA. Zeitschrift fur Gefasskrankheiten, , Volume: 13, Issue:4, 1984
Early morphological changes in the endothelium of a peripheral artery of rabbits fed an atherogenic diet.Experimental and molecular pathology, , Volume: 38, Issue:1, 1983
[Plasma thromboxane B2 and capacity of the aorta to produce prostacyclin in arteriopathies of the lower extremities].Journal des maladies vasculaires, , Volume: 8, Issue:3, 1983
Prostacyclin from the uterus and woman's cardiovascular advantage.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:5, 1982
Chronic rejection in rat aortic allografts. IV. Effect of hypercholesterolemia in allograft arteriosclerosis.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , Volume: 12, Issue:1 Pt 1
Alteration in prostacyclin and prostaglandin E2 production. Correlation with changes in human aortic atherosclerotic disease.Arteriosclerosis (Dallas, Tex.), , Volume: 4, Issue:1
Progression of carotid atherosclerosis and the role of endothelin in diabetic patients.Research communications in molecular pathology and pharmacology, , Volume: 108, Issue:1-2
Modulation of nitric oxide and 6-keto-prostaglandin F(1alpha) production in bovine aortic endothelial cells by conjugated linoleic acid.Endothelium : journal of endothelial cell research, , Volume: 11, Issue:3-4
[The content of stable forms of prostacyclin I2 and thromboxane A2 in the blood plasma in diabetic angiopathies].Problemy endokrinologii, , Volume: 37, Issue:4
Uremic levels of oxalic acid suppress replication and migration of human endothelial cells.Arteriosclerosis (Dallas, Tex.), , Volume: 10, Issue:2
[Local changes in prostanoids in arteriosclerosis obliterans].Nihon Geka Gakkai zasshi, , Volume: 90, Issue:4, 1989
[Pentoxifylline and prostaglandins].La Ricerca in clinica e in laboratorio, , Volume: 18 Suppl 2, 1988
Some haemorheological factors in patients with arteriosclerosis obliterans after treatment of trental.Folia haematologica (Leipzig, Germany : 1928), , Volume: 114, Issue:4, 1987
Thromboxane B2, 6-keto-PGF1 alpha, PGE2, PGF2 alpha, and PGA1 plasma levels in arteriosclerosis obliterans: relationship to clinical manifestations, risk factors, and arterial pathoanatomy.American heart journal, , Volume: 107, Issue:1, 1984
Prostacyclin and blood glucose levels in humans and rabbits.Prostaglandins, , Volume: 21, Issue:1, 1981
Lack of effect of ischemia and dipyridamole on prostacyclin production in arteriosclerosis obliterans.Prostaglandins, , Volume: 21, Issue:5, 1981
Intra-articular injection of hyaluronic acid reduces total amounts of leukotriene C4, 6-keto-prostaglandin F1alpha, prostaglandin F2alpha and interleukin-1beta in synovial fluid of patients with internal derangement in disorders of the temporomandibular jThe British journal of oral & maxillofacial surgery, , Volume: 36, Issue:1, 1998
Antiinflammatory effect of tepoxalin: blood and synovial tissue studied in patients with knee arthrosis.Acta orthopaedica Scandinavica, , Volume: 69, Issue:3, 1998
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Can urinary eicosanoids be a potential predictive marker of clinical response to thromboxane A2 receptor antagonist in asthmatic patients?Respiratory medicine, , Volume: 93, Issue:12, 1999
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"Ex vivo" release of eicosanoid from human brain tissue: its relevance in the development of brain edema.Neurosurgery, , Volume: 28, Issue:6, 1991
Eicosanoid production by brain tumours in vivo--evidence for intracranial compartmentation.Journal of neuro-oncology, , Volume: 11, Issue:3, 1991
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Prostaglandins in breast cancer: relationship to disease stage and hormone status.British journal of cancer, , Volume: 48, Issue:5, 1983
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Breast cancer, its recurrence, and patient survival in relation to tumor prostaglandins.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 12, 1983
Seawater Immersion Aggravates Burn Injury Causing Severe Blood Coagulation Dysfunction.BioMed research international, , Volume: 2016, 2016
Effects of amide local anaesthetics on eicosanoid formation in burned skin.Acta anaesthesiologica Scandinavica, , Volume: 43, Issue:6, 1999
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A prospective clinical study on the pathogenesis of multiple organ failure in severely burned patients.Burns : journal of the International Society for Burn Injuries, , Volume: 18, Issue:1, 1992
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Inhibition of thromboxane synthetase accentuates hemodynamic instability and burn edema in the anesthetized sheep model.Surgery, , Volume: 105, Issue:5, 1989
Nonsteroidal anti-inflammatory drugs correct the bactericidal defect of polymorphonuclear leukocytes in a guinea pig model of thermal injury.The Journal of infectious diseases, , Volume: 157, Issue:5, 1988
Topical ibuprofen decreases early postburn edema.Surgery, , Volume: 102, Issue:5, 1987
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Comparison of the postburn hyperdynamic state and changes in lung function (effect of wound bacterial content).Surgery, , Volume: 100, Issue:5, 1986
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Promotion of vascular patency in dermal burns with ibuprofen.The American journal of medicine, , Jul-13, Volume: 77, Issue:1A, 1984
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Sensitivity of tumoricidal function in macrophages from different anatomical sites of cancer patients to modulation of arachidonic acid metabolism.Cancer research, , Jul-15, Volume: 53, Issue:14, 1993
Suppression of the nitric oxide pathway in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-signaling inhibitors.Hypertension (Dallas, Tex. : 1979), , Volume: 56, Issue:6, 2010
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Increased thromboxane A2 production at primary tumor site in metastasizing squamous cell carcinoma of the larynx.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:1, 1993
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[Determinations of CSF and plasma concentrations of thromboxane B2 and 6-keto-PGF1 alpha in stroke patients].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 21, Issue:1, 1988
[Plasma concentrations of thromboxane B2 and 6-keto-PGF1 alpha in patients with cerebral hemorrhage].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 21, Issue:1, 1988
Elevated levels of immunoreactive prostacyclin metabolite in babies who develop intraventricular haemorrhage.Acta paediatrica Scandinavica, , Volume: 76, Issue:1, 1987
Ethamsylate reduces immunoreactive prostacyclin metabolite in low birthweight infants with respiratory distress syndrome.Early human development, , Volume: 14, Issue:3-4, 1986
Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants.The Journal of pediatrics, , Volume: 107, Issue:6, 1985
Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Dissecting Xuesaitong's mechanisms on preventing stroke based on the microarray and connectivity map.Molecular bioSystems, , Volume: 11, Issue:11, 2015
Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats.Chinese journal of integrative medicine, , Volume: 19, Issue:2, 2013
Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain.The American journal of Chinese medicine, , Volume: 39, Issue:2, 2011
[A further research on physiopathological basis of "Liver Yang Forming Wind Syndrome"].Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, , Aug-28, Volume: 25, Issue:4, 2000
[Exploration on parameters of TCM syndrome in acute cerebral infarction through investigating active factors of vascular endothelium cells].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 20, Issue:12, 2000
[Clinical study on active factors of vascular endothelial cells in acute cerebral infarction patients and therapeutical effect of activating blood stasis].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:7, 1998
[Pathophysiological basis of 3 subtypes in ganfeng neidong syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:7, 1993
Effect of a novel thromboxane A2 receptor antagonist, S-1452, on postischemic brain injury in rats.Stroke, , Volume: 24, Issue:12, 1993
[Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in patients with acute cerebral infarction].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:12, 1991
[Status of the prostacyclin-thromboxane balance in patients with cerebrovascular disorders and the effect of the treatment with nifedipine].Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), , Volume: 91, Issue:7, 1991
[Treatment of acute cerebral infarction with PGI2--evaluating the clinical effect and observation of dynamic changes in plasma TXB2 and 6-keto PGF1 alpha levels].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 24, Issue:3, 1991
[Changes in plasma 6-keto-PGF1 alpha, TXB2 lipid peroxides in acute cerebral infarction patients and the effects of Salvia miltiorrhiza on these three indices].Zhonghua nei ke za zhi, , Volume: 27, Issue:10, 1988
[Determinations of CSF and plasma concentrations of thromboxane B2 and 6-keto-PGF1 alpha in stroke patients].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 21, Issue:1, 1988
The midnight-noon ebb-flow point selection for 30 cases of acute ischemic cerebrovascular diseases.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 28, Issue:3, 2008
Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion.The Journal of nutritional biochemistry, , Volume: 17, Issue:4, 2006
[Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats].Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, , Volume: 27, Issue:5, 2004
[Comparison of effect of Astragalus membranaceus and huoxuefang on thromboxane, prostacyclin and adenosine cyclic monophosphate in cerebral reperfusion injury in rabbits].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:3, 1995
[Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 30, Issue:2, 1995
Effects of MK-801 and ganglioside GM1 on postischemic prostanoid release and hippocampal lesion in gerbil brain.Acta neurobiologiae experimentalis, , Volume: 54, Issue:4, 1994
Pyrazolopyridine derivative acts as a novel cyclooxygenase inhibitor: antiplatelet effect in aged patients with ischemic stroke.Journal of the American Geriatrics Society, , Volume: 42, Issue:6, 1994
[Role of arachidonic acid metabolites on development of ischemic cerebral edema in rat middle cerebral artery occlusion].No to shinkei = Brain and nerve, , Volume: 46, Issue:1, 1994
NMDA receptors mediate anoxia/aglycemia-induced release of eicosanoids in immature rat hippocampal slices: utility of an in vitro "ischemic" superfusion model with temporary arrest of medium flow.Folia neuropathologica, , Volume: 32, Issue:3, 1994
Differential temperature sensitivity of ischemia-induced glutamate release and eicosanoid production in rats.Brain research, , Jul-11, Volume: 650, Issue:2, 1994
Effect of ibuprofen on regional eicosanoid production and neuronal injury after forebrain ischemia in rats.Brain research, , Jun-18, Volume: 614, Issue:1-2, 1993
Transforming growth factor-beta attenuates ischemia-induced alterations in cerebrovascular responses.The American journal of physiology, , Volume: 264, Issue:2 Pt 2, 1993
Superoxide scavengers do not prevent ischemia-induced alteration of cerebral vasodilation in piglets.Pediatric research, , Volume: 33, Issue:2, 1993
Effect of policosanol on cerebral ischemia in Mongolian gerbils: role of prostacyclin and thromboxane A2.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:3, 1993
[The effect of hyperbaric oxygenation on prostaglandin I2 and thromboxane A2 during reperfusion for experimental cerebral ischemia in rabbits].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 25, Issue:1, 1992
Eicosanoid production in the caudate nucleus and dorsal hippocampus after forebrain ischemia: a microdialysis study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 12, Issue:1, 1992
Changes in endogenous prostacyclin in the rat brain during clinical death and after resuscitation.Neuropatologia polska, , Volume: 30, Issue:2, 1992
Studies on eicosanoid metabolism in the fetal rat brain after global ischemia.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21B, 1991
[Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in rabbits under acute experimental cerebral ischemia].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:9, 1990
Ischemia alters cerebral vascular responses to hypercapnia and acetylcholine in piglets.Pediatric research, , Volume: 25, Issue:2, 1989
Prostaglandin profiles in relation to local circulatory changes following focal cerebral ischemia in cats.Stroke, , Volume: 20, Issue:6, 1989
Effect of thromboxane synthase inhibition on eicosanoid levels and blood flow in ischemic rat brain.Stroke, , Volume: 20, Issue:5, 1989
Combination therapy with low-dose aspirin and ticlopidine in cerebral ischemia.Stroke, , Volume: 20, Issue:12, 1989
Effects of gangliosides on the formation of eicosanoids in rat brain cerebral ischemia and reperfusion.Pharmacological research communications, , Volume: 20 Suppl 5, 1988
Time course of release in vivo of PGE2, PGF2 alpha, 6-keto-PGF1 alpha, and TxB2 into the brain extracellular space after 15 min of complete global ischemia in the presence and absence of cyclooxygenase inhibition.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 8, Issue:6, 1988
[The effect of glucose and insulin on carbohydrate and prostaglandin metabolism in the ischemic brain].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 21, Issue:6, 1988
A possible role of endogenously formed cerebral prostaglandins in the development of adaptive protection against cerebral hypoxia/ischemia in mice.Methods and findings in experimental and clinical pharmacology, , Volume: 9, Issue:11, 1987
Comparison of the effect of acetylsalicylic acid on platelet function in male and female patients with ischemic stroke.Thrombosis research, , Aug-01, Volume: 47, Issue:3, 1987
Arachidonic acid-induced brain ischaemia: different severity between stroke-resistant spontaneously hypertensive rats and Wistar-Kyoto rats.Journal of hypertension. Supplement : official journal of the International Society of Hypertension, , Volume: 4, Issue:3, 1986
Prostanoid concentrations in human CSF following acute ischaemic brain infarction.Clinical and experimental pharmacology & physiology, , Volume: 13, Issue:8, 1986
[Effect of bilateral common carotid artery ligation on prostaglandin levels (TXA2, PGI2) in spontaneously hypertensive rats (SHRSP, SHRSR) and normotensive rats (WKY)].No to shinkei = Brain and nerve, , Volume: 38, Issue:6, 1986
Lipoxygenase metabolites of arachidonic acid and the development of ischaemic cerebral oedema.Neurological research, , Volume: 8, Issue:1, 1986
Modification of brain vascular eicosanoids after pharmacological treatment and ischemia in the rat: drugs and brain vascular eicosanoids.Cephalalgia : an international journal of headache, , Volume: 5 Suppl 2, 1985
[Prostaglandin metabolism in ischemic brain edema].Nihon geka hokan. Archiv fur japanische Chirurgie, , Sep-01, Volume: 54, Issue:5, 1985
Polyamine and prostaglandin markers in focal cerebral ischemia.Neurosurgery, , Volume: 17, Issue:4, 1985
Postischemic production of eicosanoids in gerbil brain.Stroke, , Volume: 18, Issue:1
Ibuprofen improves cerebral blood flow after global cerebral ischemia in dogs.Stroke, , Volume: 18, Issue:4
The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain.Stroke, , Volume: 13, Issue:4
The effect of a thromboxane synthetase inhibitor, OKY-046, on urinary excretion of immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in patients with ischemic cerebrovascular disease.Stroke, , Volume: 16, Issue:2
Effect of ozagrel on locomotor and motor coordination after transient cerebral ischemia in experimental animal models.Pharmacology, , Volume: 59, Issue:5, 1999
Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto-PGF1 alpha in rat brain during focal cerebral ischemia and reperfusion.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 18, Issue:6, 1997
Effect of a novel thromboxane A2 receptor antagonist, S-1452, on postischemic brain injury in rats.Stroke, , Volume: 24, Issue:12, 1993
Microdialysis measurements of PGD2, TXB2 and 6-KETO-PGF1 alpha in rat CA1 hippocampus during transient cerebral ischemia.Prostaglandins, , Volume: 45, Issue:2, 1993
Ex vivo release of eicosanoids after aneurysmal subarachnoid hemorrhage: a preliminary experience in humans.Acta neurologica Scandinavica, , Volume: 86, Issue:2, 1992
[The study of occurrence mechanism in acute and chronic cerebral vasospasm].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 25, Issue:6, 1992
Effects of ischemia/reperfusion on brain tissue prostanoids and leukotrienes in newborn pigs.Prostaglandins, , Volume: 42, Issue:6, 1991
Anti-lipid peroxidation and protection of ginsenosides against cerebral ischemia-reperfusion injuries in rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 11, Issue:2, 1990
Arachidonic acid metabolite production following focal cerebral ischemia: time course and effect of meclofenamate.Surgical neurology, , Volume: 33, Issue:1, 1990
Accumulation of arachidonic acid cyclo- and lipoxygenase products in rat brain during ischemia and reperfusion: effects of treatment with GM1-lactone.Journal of neurochemistry, , Volume: 53, Issue:3, 1989
Prevention of chronic cerebral vasospasm in dogs with ibuprofen and high-dose methylprednisolone.Stroke, , Volume: 20, Issue:8, 1989
Effects of vasospasm on levels of prostacyclin and thromboxane A2 in cerebral arteries of the monkey.Neurosurgery, , Volume: 22, Issue:1 Pt 1, 1988
Thromboxane synthetase inhibition with imidazole increases blood flow in ischemic penumbra.Neurosurgery, , Volume: 22, Issue:2, 1988
Cisternal and lumbar CSF levels of arachidonate metabolites after subarachnoid haemorrhage: an assessment of the biochemical hypothesis of vasospasm.Acta neurochirurgica, , Volume: 84, Issue:3-4, 1987
Arachidonic acid metabolism following aneurysm rupture. Evaluation of cerebrospinal fluid and serum concentration of 6-keto-prostaglandin F1 alpha and thromboxane B2 in patients with subarachnoid hemorrhage.Surgical neurology, , Volume: 27, Issue:3, 1987
Role of arachidonate metabolites in the genesis of cerebral vasospasm.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 17B, 1987
[Sequential measurements of TxB2 and 6-keto PGF1 alpha in cerebrospinal fluid and serum in patients with subarachnoid hemorrhage].Neurologia medico-chirurgica, , Volume: 26, Issue:4, 1986
[Cerebral vasospasm. Clinical and experimental aspects].Minerva medica, , Jun-08, Volume: 77, Issue:24, 1986
[Arachidonic acid metabolism following aneurysm rupture].European archives of psychiatry and neurological sciences, , Volume: 236, Issue:2, 1986
Development of cyclooxygenase and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia.Journal of neurosurgery, , Volume: 64, Issue:1, 1986
Beneficial effect of OKY-046, a selective thromboxane A2 synthetase inhibitor, on experimental cerebral vasospasm.Japanese journal of pharmacology, , Volume: 41, Issue:3, 1986
Arachidonate metabolites and vasospasm after subarachnoid haemorrhage.Neurological research, , Volume: 8, Issue:1, 1986
Prostacyclin and vasospasm in subarachnoid hemorrhage from ruptured intracranial aneurysm. A preliminary clinical study.Acta neurologica Scandinavica, , Volume: 73, Issue:1, 1986
Cisternal and lumbar CSF concentration of arachidonate metabolites in vasospasm following subarachnoid hemorrhage from ruptured aneurysm: biochemical and clinical considerations.Surgical neurology, , Volume: 24, Issue:4, 1985
Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 19, Issue:1, 1999
[Research on plasma TXA2, PGI2 levels, blood stasis syndrome and promoting blood circulation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:11, 1995
Pyrazolopyridine derivative acts as a novel cyclooxygenase inhibitor: antiplatelet effect in aged patients with ischemic stroke.Journal of the American Geriatrics Society, , Volume: 42, Issue:6, 1994
Effect of low-dose treatment with perindopril on cardiac function in stroke-prone spontaneously hypertensive rats: role of bradykinin.Journal of cardiovascular pharmacology, , Volume: 24, Issue:3, 1994
Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin.Stroke, , Volume: 23, Issue:10, 1992
Protective effect of cicletanine on hypertension-induced decreases in the renal kallikrein-kinin and prostaglandin systems in stroke-prone spontaneously hypertensive rats.Journal of cardiovascular pharmacology, , Volume: 20, Issue:4, 1992
Changes in endogenous prostacyclin in the rat brain during clinical death and after resuscitation.Neuropatologia polska, , Volume: 30, Issue:2, 1992
[Plasma levels of prostaglandins and leukotrienes in vascular diseases].La Ricerca in clinica e in laboratorio, , Volume: 19 Suppl 1, 1989
Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema.Stroke, , Volume: 19, Issue:3, 1988
Arachidonic acid-induced brain ischaemia: different severity between stroke-resistant spontaneously hypertensive rats and Wistar-Kyoto rats.Journal of hypertension. Supplement : official journal of the International Society of Hypertension, , Volume: 4, Issue:3, 1986
[Mechanisms of changes in the sensitivity of platelets to prostacyclin in patients with cerebrovascular diseases].Voprosy meditsinskoi khimii, , Volume: 34, Issue:6
Synthetic pathways of gallbladder mucosal prostanoids: the role of cyclooxygenase-1 and 2.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 60, Issue:2, 1999
Regulation of eicosanoid synthesis in fibroblasts from inflamed gallbladders.Molecular and cellular endocrinology, , Nov-30, Volume: 115, Issue:1, 1995
Platelet activating factor (PAF) stimulates release of PGI2 from inflamed rabbit gallbladder cell cultures.Prostaglandins, , Volume: 50, Issue:1, 1995
Increased intragallbladder pressure stimulates gallbladder eicosanoid release.Prostaglandins, , Volume: 48, Issue:1, 1994
Acute cholecystitis potentiates bradykinin stimulated fibroblast prostanoid release in the rabbit.Molecular and cellular endocrinology, , Volume: 95, Issue:1-2, 1993
Human cholecystitis is associated with increased gallbladder prostaglandin I2 and prostaglandin E2 synthesis.Hepatology (Baltimore, Md.), , Volume: 16, Issue:5, 1992
Profiling of eicosanoids in inflamed gall bladder wall by gas chromatography with selected-ion monitoring.Journal of chromatography, , Nov-15, Volume: 571, Issue:1-2, 1991
The role of prostanoids in the production of acute acalculous cholecystitis by platelet-activating factor.Annals of surgery, , Volume: 212, Issue:4, 1990
Common bile ligation in the rabbit: an appropriate model for investigating the relationship of endogenous gallbladder prostanoid synthesis with evolving acute inflammation.Prostaglandins, , Volume: 40, Issue:2, 1990
The effects of thromboxane A2 synthetase inhibitor (OKY-046) on complete hepatic ischemia in rats with obstructive jaundice.Surgery today, , Volume: 26, Issue:1, 1996
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction.Hepatology (Baltimore, Md.), , Volume: 18, Issue:1, 1993
Role of renal sympathetic nerve activity in renal failure associated with obstructive jaundice in the rat.American journal of surgery, , Volume: 161, Issue:6, 1991
Enhanced production of endogenous prostaglandin in obstructive jaundiced pancreas in dogs.Gastroenterology, , Volume: 98, Issue:5 Pt 1, 1990
Urinary prostaglandins and renal function in obstructive jaundice.Scandinavian journal of gastroenterology, , Volume: 24, Issue:6, 1989
Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice.The British journal of surgery, , Volume: 69, Issue:10, 1982
Enhanced external counterpulsation improves peripheral artery flow-mediated dilation in patients with chronic angina: a randomized sham-controlled study.Circulation, , Oct-19, Volume: 122, Issue:16, 2010
[Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University, , Volume: 30, Issue:6, 2010
Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats.World journal of gastroenterology, , Dec-07, Volume: 11, Issue:45, 2005
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs.American journal of physiology. Lung cellular and molecular physiology, , Volume: 284, Issue:2, 2003
[Clinical and experimental study of treatment of nanmiqing capsule for chronic prostatitis].Zhonghua nan ke xue = National journal of andrology, , Volume: 8, Issue:5, 2002
Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension.Cardiovascular research, , Volume: 55, Issue:1, 2002
Arachidonic acid metabolites in antrochoanal polyp and nasal polyp associated with chronic paranasal sinusitis.Acta oto-laryngologica, , Volume: 120, Issue:4, 2000
Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study.American journal of obstetrics and gynecology, , Volume: 177, Issue:6, 1997
Urinary excretion of prostanoids in children with chronic pyelonephritis.Advances in experimental medicine and biology, , Volume: 400B, 1997
Prostacyclin and thromboxane A2 synthesis are increased in acute lower limb ischaemia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 55, Issue:6, 1996
Intermittent pneumatic compression in chronic venous insufficiency favorably affects fibrinolytic potential and platelet activation.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, , Volume: 7, Issue:4, 1996
[The clinico-biochemical characteristics of periodontal diseases in subjects who are under conditions of constant, permanent stress].Stomatologiia, , Volume: 75, Issue:1, 1996
Lipid mediator production in acute and chronic pancreatitis in the rat.The Journal of surgical research, , Volume: 56, Issue:1, 1994
Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction.The American journal of cardiology, , Jun-01, Volume: 73, Issue:15, 1994
Healing of chronic gastric ulcer depends on gastric mucosal prostaglandin synthesis.Hepato-gastroenterology, , Volume: 41, Issue:2, 1994
Chronic gastritis, prostaglandins and Helicobacter pylori.Zeitschrift fur Gastroenterologie, , Volume: 31, Issue:10, 1993
[The functional characteristics of the prostacyclin-thromboxane system in newborn infants with a history of acute and chronic intrauterine hypoxia].Akusherstvo i ginekologiia, , Issue:6, 1993
[The effect of decreased thromboxane synthesis on proliferative glomerulonephritis].Casopis lekaru ceskych, , Oct-18, Volume: 130, Issue:16-17, 1991
[Prostacyclin and thromboxane synthesis in liver tissue in chronic liver diseases].Zeitschrift fur medizinische Laboratoriumsdiagnostik, , Volume: 31, Issue:6, 1990
The relationship of prostaglandins to cAMP, IgG, IgM and alpha-2-macroglobulin in gingival crevicular fluid in chronic adult periodontitis.Archives of oral biology, , Volume: 35, Issue:8, 1990
[The leukotriene B4 content of the bronchoalveolar lavage fluid and the function of the prostacyclin-thromboxane system in patients with variants of chronic bronchitis].Terapevticheskii arkhiv, , Volume: 62, Issue:4, 1990
Effects of sulindac and naproxen on prostaglandin excretion in patients with impaired renal function and rheumatoid arthritis.The American journal of medicine, , Volume: 89, Issue:3, 1990
Prostacyclin and noradrenaline in peripheral nerve of chronic experimental diabetes in rats.Brain : a journal of neurology, , Volume: 112 ( Pt 1), 1989
[The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses].Vestnik dermatologii i venerologii, , Issue:1, 1989
Peritoneal fluid eicosanoids in chronic pelvic pain.Prostaglandins, , Volume: 38, Issue:4, 1989
[Prostaglandins and chronic proliferative glomerulonephritis].Casopis lekaru ceskych, , Jan-13, Volume: 128, Issue:3, 1989
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.Gastroenterology, , Volume: 96, Issue:1, 1989
Effects of chronic fetal hyperinsulinemia on plasma arachidonic acid and prostaglandin concentrations.American journal of obstetrics and gynecology, , Volume: 161, Issue:4, 1989
Prostaglandins in human cholesteatoma and granulation tissue.The American journal of otology, , Volume: 9, Issue:3, 1988
Effects of treadmill and pacing stress testing on peripheral arterial thromboxane, platelet function and catecholamine activities in patients with chronic coronary artery disease.Japanese journal of medicine, , Volume: 26, Issue:1, 1987
[Content of endogenous prostanoids in patients with paroxysmal supraventricular disorders of the heart rhythm].Kardiologiia, , Volume: 26, Issue:6, 1986
Importance of renal prostaglandins in control of renal function after chronic ligation of the common bile duct in dogs.The Journal of laboratory and clinical medicine, , Volume: 103, Issue:4, 1984
Peritoneal fluid prostaglandins and prostanoids in women with endometriosis, chronic pelvic inflammatory disease, and pelvic pain.American journal of obstetrics and gynecology, , Feb-15, Volume: 148, Issue:4, 1984
Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin.The New England journal of medicine, , Feb-02, Volume: 310, Issue:5, 1984
Decrease prostacyclin production: a characteristic of chronic placental insufficiency syndromes.Lancet (London, England), , May-23, Volume: 1, Issue:8230, 1981
Enhanced 6-oxo-PGF1 alpha levels in plasma during hemodialysis.Prostaglandins and medicine, , Volume: 5, Issue:6, 1980
Enhanced prostacyclin synthesis in acute human kidney transplant rejection.Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, , Volume: 17, 1980
Chronic rejection in rat aortic allografts. IV. Effect of hypercholesterolemia in allograft arteriosclerosis.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , Volume: 12, Issue:1 Pt 1
[Prostaglandins content in the blood of newborns with various types of hypoxia].Fiziologicheskii zhurnal, , Volume: 39, Issue:2-3
[Tissue levels of 6-ketoprostaglandin Fl alpha and integrity of gastric mucosa in patients with Chagas disease].Arquivos de gastroenterologia, , Volume: 28, Issue:4
Effect of post-treatment with granulocyte colony-stimulating factor on endotoxin-induced lung injury in sheep.Experimental lung research, , Volume: 24, Issue:1
Release of prostanoids into the portal and hepatic vein in patients with chronic liver disease.Hepatology (Baltimore, Md.), , Volume: 6, Issue:5
Specific neutrophil elastase inhibitor does not attenuate acute lung injury induced by air embolism in awake sheep.Experimental lung research, , Volume: 22, Issue:6
Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.European journal of pharmacology, , Oct-15, Volume: 789, 2016
Colon-targeted celecoxib ameliorates TNBS-induced rat colitis: a potential pharmacologic mechanism and therapeutic advantages.European journal of pharmacology, , Mar-05, Volume: 726, 2014
Effect of methylprednisolone on the ulceration, matrix metalloproteinase distribution and eicosanoid production in a model of colitis in the rabbit.International journal of experimental pathology, , Volume: 78, Issue:6, 1997
Platelet-activating factor mediates trinitrobenzene induced colitis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:6, 1994
Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis.Gastroenterology, , Volume: 98, Issue:2, 1990
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.Gastroenterology, , Volume: 96, Issue:1, 1989
The effect of anti-inflammatory drugs on eicosanoid formation in a chronic model of inflammatory bowel disease in the rat.British journal of pharmacology, , Volume: 94, Issue:1, 1988
Nicotine inhibits cytokine synthesis by mouse colonic mucosa.European journal of pharmacology, , May-04, Volume: 278, Issue:1, 1995
Species differences in the pattern of eicosanoids produced by inflamed and non-inflamed tissue.Agents and actions, , Volume: Spec No, 1992
Smoking, eicosanoids and ulcerative colitis.The Journal of pharmacy and pharmacology, , Volume: 42, Issue:4, 1990
[Thromboxane analyses in patients with chronic inflammatory bowel diseases].Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, , Volume: 46, Issue:4, 1986
[Arachidonic acid metabolism in inflammatory bowel disease--with reference to cyclooxygenase products].Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, , Volume: 82, Issue:10, 1985
Prostanoid synthesis by cultured peripheral blood mononuclear cells in inflammatory diseases of the bowel.Gastroenterology, , Volume: 82, Issue:4, 1982
Antithrombin reduces reperfusion-induced hepatic metastasis of colon cancer cells.World journal of gastroenterology, , Jan-07, Volume: 12, Issue:1, 2006
Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer.Clinical cancer research : an official journal of the American Association for Cancer Research, , Volume: 7, Issue:11, 2001
Effects of dietary fibre on dimethylhydrazine-induced changes in prostanoid concentrations in rat colonic mucosa.Clinical and experimental pharmacology & physiology, , Volume: 22, Issue:10, 1995
Modulating effect of amount and types of dietary fat on ornithine decarboxylase, tyrosine protein kinase and prostaglandins production during colon carcinogenesis in male F344 rats.Carcinogenesis, , Volume: 14, Issue:7, 1993
Biological half-life of prostacyclin and 6-oxo-PGF1 alpha levels in plasma of patients with colonic cancer.Prostaglandins, leukotrienes, and medicine, , Volume: 22, Issue:3, 1986
PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells.Anticancer research, , Volume: 24, Issue:3a
Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics.International journal of molecular medicine, , Volume: 27, Issue:4, 2011
Sickle cell vaso-occlusive crisis is associated with abnormalities in the ratio of vasoconstrictor to vasodilator prostanoids.Pediatric research, , Volume: 38, Issue:1, 1995
[Contents of 6-keto-prostaglandin F1 alpha and thromboxane B2 in the blood of patients with bronchial asthma].Klinicheskaia meditsina, , Volume: 68, Issue:11, 1990
Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog.The American journal of physiology, , Volume: 248, Issue:4 Pt 2, 1985
Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 112, Issue:5, 2012
Interaction between COX-2 G-765C and smoking in relation to coronary artery disease in a Chinese Uighur population.Clinical chemistry and laboratory medicine, , Volume: 49, Issue:1, 2011
Diagnostic biomarkers of essential arterial hypertension: the value of prostacyclin, nitric oxide, oxidized-LDL, and peroxide measurements.International heart journal, , Volume: 50, Issue:3, 2009
NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.Basic research in cardiology, , Volume: 103, Issue:5, 2008
Plasma levels of von willebrand factor, endothelin-1, prostacyclin and thromboxane in children from families with high risk of premature coronary artery disease.Scandinavian journal of clinical and laboratory investigation, , Volume: 61, Issue:4, 2001
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice.Proceedings of the National Academy of Sciences of the United States of America, , Mar-13, Volume: 98, Issue:6, 2001
Free radicals in myocardial injury: experimental and clinical studies.Molecular and cellular biochemistry, , Volume: 111, Issue:1-2, 1992
Short-term therapy of atherosclerosis with low dose indomethacin: an experimental study.Journal of medical primatology, , Volume: 19, Issue:7, 1990
[Pathogenetic and therapeutic significance of the angioprotective systems in patients with coronary arteriosclerosis].Kardiologiia, , Volume: 30, Issue:12, 1990
[Prostaglandins and thromboxane in coronary arteriosclerosis].Kardiologiia, , Volume: 27, Issue:10, 1987
Plasma level of mitochondrial coupling factor 6 increases in patients with coronary heart disease.Circulation journal : official journal of the Japanese Circulation Society, , Volume: 71, Issue:5, 2007
Low dose rofecoxib, inflammation and prostacyclin synthesis in acute coronary syndromes.Roczniki Akademii Medycznej w Bialymstoku (1995), , Volume: 50, 2005
Intravenous aspirin at reperfusion does not reduce infarct size in the dog with a residual critical stenosis.Journal of cardiovascular pharmacology, , Volume: 34, Issue:4, 1999
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.Journal of cardiovascular pharmacology, , Volume: 33, Issue:2, 1999
The effects of endurance training on selected coronary risk factors in children.Acta paediatrica (Oslo, Norway : 1992), , Volume: 87, Issue:4, 1998
Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease.Angiology, , Volume: 48, Issue:6, 1997
[Study on relationship of lipid peroxide in coronary heart disease with and without diabetes].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:1, 1996
[Study on mechanism of eye-signs in blood stasis syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:4, 1996
Seasonal variation in parameters related to coronary heart disease risk in young men.Atherosclerosis, , Sep-27, Volume: 126, Issue:1, 1996
[Research on plasma TXA2, PGI2 levels, blood stasis syndrome and promoting blood circulation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:11, 1995
Platelet aggregation, coronary artery disease progression and future coronary events.The American journal of cardiology, , Feb-15, Volume: 73, Issue:5, 1994
Type A behavior and alcohol consumption: effects on resting and post-exercise bleeding time thromboxane and prostacyclin metabolites.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 48, Issue:2, 1993
[Comparison of lipoperoxidative damage in plasma and platelet with the ratio of thromboxane A2 and prostaglandin I2 in blood stasis syndrome with coronary heart disease].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:11, 1993
[Changes in TXB2/6-keto-PGF1 alpha ratio and their relation to blood lipids of Type A behavioral patterns].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 24, Issue:4, 1993
Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking.Journal of the American College of Cardiology, , Volume: 22, Issue:4, 1993
Effects of early angiotensin-converting enzyme inhibition in a pig model of myocardial ischemia and reperfusion.Journal of cardiovascular pharmacology, , Volume: 19, Issue:3, 1992
Oral cicaprost protects from hypercholesterolaemia-induced impairment of coronary vasodilation.Agents and actions. Supplements, , Volume: 37, 1992
The effects of testosterone on lipids and eicosanoids in cynomolgus monkeys.Medicine and science in sports and exercise, , Volume: 24, Issue:3, 1992
Opposite effects of PGI2 and PAF generated during acute myocardial ischemia in the perfused rabbit heart.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21B, 1991
[The relation between coronary diseases and lipid peroxidation].Zhonghua xin xue guan bing za zhi, , Volume: 19, Issue:3, 1991
Pacing-induced myocardial ischemia does not affect the endothelial release of coagulant and fibrinolytic factors into the coronary circulation.Clinical cardiology, , Volume: 14, Issue:3, 1991
[Participation of the prostacyclin-thromboxane system in the mechanisms of prevention of arrhythmia caused by occlusion of the coronary artery in adapted rats].Biulleten' eksperimental'noi biologii i meditsiny, , Volume: 111, Issue:1, 1991
Cicletanine and reperfusion injury: is there any correlation between arrhythmias, 6-keto-PGF1 alpha, thromboxane B2, and myocardial ion shifts (Na+, K+, Ca2+, and Mg2+) induced by ischemia/reperfusion in isolated rat heart.Journal of cardiovascular pharmacology, , Volume: 17, Issue:4, 1991
Reduced prostaglandin release from the stunned porcine heart--significance for attenuated reactive hyperaemia.Cardiovascular research, , Volume: 25, Issue:7, 1991
Ridogrel in the setting of percutaneous transluminal coronary angioplasty.The American journal of cardiology, , Aug-15, Volume: 68, Issue:5, 1991
[Status of the thrombocytic-vascular component of the hemostasis system in the population of the Far North].Vestnik Akademii meditsinskikh nauk SSSR, , Issue:10, 1991
[Relation of coronary heart disease based on traditional Chinese medicine syndrome differentiation and prostaglandin, blood platelet function, and protein C].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:5, 1991
Effect of ubiquinone on ischemic arrhythmia in conscious rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 12, Issue:3, 1991
Low level of prostacyclin as a risk of ischaemic heart disease.International journal of cardiology, , Volume: 30, Issue:2, 1991
Interactions between nitric oxide and prostacyclin in myocardial ischemia and endothelial cell cultures.Basic research in cardiology, , Volume: 86 Suppl 2, 1991
[Effects of svate on platelet morphology and function in patients with coronary heart disease and hypertension].Zhonghua xin xue guan bing za zhi, , Volume: 19, Issue:3, 1991
Effect of aspirin on local prostaglandin production and serotonin accumulation in a canine model with coronary cyclic flow variations or thrombosis.Journal of molecular and cellular cardiology, , Volume: 23, Issue:4, 1991
[Relation of pale tongue, purple tongue and TXA2-PGI2 regulation system].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:4, 1990
Effects of a low, oral dose of nisoldipine on the systemic and coronary hemodynamics and the prostaglandin metabolism of ischemic heart disease patients.Japanese heart journal, , Volume: 31, Issue:3, 1990
Coronary endothelium-protective effects of defibrotide in ischaemia and reperfusion.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 341, Issue:3, 1990
Effects of vitamin E on prostacyclin release and lipid composition of the ischemic rat heart.Archives of biochemistry and biophysics, , Volume: 277, Issue:2, 1990
Longitudinal and cross-sectional studies of the relationship between 6-keto PGF1 alpha and high density lipoproteins.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:2, 1990
[The effect of eicosapentaenoic acid enriched marine oil on the platelet function in hypercoagulable state].Zhonghua nei ke za zhi, , Volume: 29, Issue:7, 1990
[Responses of plasma eicosanoids and hemodynamics to myocardial ischemia and the salutary effect of calcium entry blocker].Nihon Ika Daigaku zasshi, , Volume: 57, Issue:1, 1990
Effects of a thromboxane A2 synthetase inhibitor on ventricular fibrillation threshold during coronary artery occlusion and reperfusion.Japanese heart journal, , Volume: 31, Issue:1, 1990
Influence of iloprost on eicosanoid generation and lipid levels in experimental myocardial ischemia in dogs.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 35, Issue:3, 1989
Ischemia-induced arachidonic acid accumulation and prostanoid release during reperfusion in the isolated rat heart.Progress in clinical and biological research, , Volume: 301, 1989
Cardiac ischemia and endothelial function in the isolated rabbit heart.The Journal of surgical research, , Volume: 47, Issue:2, 1989
Altered sensitivity to prostacyclin may be involved in the exercise-induced activation of platelets in patients with ischemic heart disease.Progress in clinical and biological research, , Volume: 301, 1989
Dynamics of prostacyclin and thromboxane during myocardial ischemia.Progress in clinical and biological research, , Volume: 308, 1989
[Effect of cardiac sympathetic nerves on changes of TXB2 and 6-keto-PGF1 alpha in venous blood of ischemic myocardium].Sheng li xue bao : [Acta physiologica Sinica], , Volume: 41, Issue:1, 1989
[Effects of experimental coronary artery stenosis on platelet function].Zhonghua xin xue guan bing za zhi, , Volume: 17, Issue:5, 1989
Plasma bradykinin and prostaglandin metabolism and exercise testing in patients with silent myocardial ischemia compared with patients with painful myocardial ischemia.Japanese circulation journal, , Volume: 53, Issue:11, 1989
Concentration-dependent effects of purine/xanthine oxidase on release of 6-keto-PGF1 alpha and contractile function of isolated guinea pig hearts: response to "ischemic" conditions followed by reperfusion.Journal of cardiovascular pharmacology, , Volume: 14, Issue:4, 1989
Effects of peptide 6A on coronary blood flow dynamics in canine coronary thrombosis.Journal of cardiovascular pharmacology, , Volume: 13, Issue:6, 1989
Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion.American heart journal, , Volume: 115, Issue:3, 1988
Effects of cicletanine in the left circumflex coronary artery occlusion-reperfusion canine model of sudden death: analysis of 107 experiments using Cox's proportional hazards model.Drugs under experimental and clinical research, , Volume: 14, Issue:2-3, 1988
Effects of coronary ischemia on lung fluid balance in conscious sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 65, Issue:2, 1988
Thromboxane B2 and 6-keto-prostaglandin F1 alpha [125I] radioimmunoassays and applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:4, 1988
Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosis.The Journal of clinical investigation, , Volume: 82, Issue:5, 1988
Assessment of prostacyclin and thromboxane A2 release during reperfusion after global ischemia induced by crystalloid cardioplegia--comparison between warm and cold ischemia.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, , Volume: 20, Issue:2, 1988
Absence of differential inhibition of thromboxane A2 and prostacyclin by low and high dose aspirin in coronary artery disease.The Canadian journal of cardiology, , Volume: 3, Issue:6, 1987
Effects of a selective thromboxane synthetase inhibitor (OKY-046) in patients with coronary artery disease during exercise.Japanese heart journal, , Volume: 28, Issue:5, 1987
[Relation between plasma thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and traditional Chinese medicine in different types of ischemic heart disease patients].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 7, Issue:1, 1987
Effects of dietary cod liver oil on fatty-acid composition and calcium transport in isolated adult rat ventricular myocytes and on the response of isolated hearts to ischemia and reperfusion.Canadian journal of physiology and pharmacology, , Volume: 65, Issue:2, 1987
Regional differences in postischemic recovery in the stunned canine myocardium.American heart journal, , Volume: 114, Issue:5, 1987
Effect of ovariectomy in humans on serum 6-keto-PGF1 alpha and TXB2 concentrations and platelet fatty acids.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:1, 1987
Effects of iloprost (ZK 36374), a prostacyclin derivative, on platelet function after ischaemic exercise in patients with stable angina pectoris.Thrombosis research, , Oct-15, Volume: 48, Issue:2, 1987
[Effects of qixue injections on the function of platelets in coronary disease patients].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 7, Issue:1, 1987
Effects of treadmill and pacing stress testing on peripheral arterial thromboxane, platelet function and catecholamine activities in patients with chronic coronary artery disease.Japanese journal of medicine, , Volume: 26, Issue:1, 1987
[Effect of chuan-xiong granules on platelet aggregation, plasma beta-thromboglobulin, platelet factor IV, thromboxane B2 and 6-keto-prostaglandin F1 alpha in coronary disease patients].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 7, Issue:1, 1987
[A clinical trial of sheng-mai liquor in the treatment of ischemic heart disease].Zhonghua xin xue guan bing za zhi, , Volume: 15, Issue:3, 1987
[Antagonism of collagen-induced ECG changes in rats by a thromboxane synthetase inhibitor, CV-4151].Nihon yakurigaku zasshi. Folia pharmacologica Japonica, , Volume: 87, Issue:4, 1986
[Status of the prostacyclin and thromboxane system, lipid metabolism and lipid peroxidation processes in patients with coronary atherosclerosis].Vrachebnoe delo, , Issue:4, 1986
Contribution of prostaglandins to reperfusion-induced ventricular failure in isolated rat hearts.The American journal of physiology, , Volume: 251, Issue:1 Pt 2, 1986
[Content of endogenous prostanoids in patients with paroxysmal supraventricular disorders of the heart rhythm].Kardiologiia, , Volume: 26, Issue:6, 1986
Prostacyclin in the circulation of patients with vascular disorders undergoing surgery.Clinical science (London, England : 1979), , Volume: 71, Issue:6, 1986
[Thromboxane and prostacyclin in patients with stenocardia in induced and spontaneous ischemia of the myocardium].Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, , Volume: 9, Issue:1, 1986
[Disorders in the status of the vessel-thrombocyte and plasma links of the hemostatic system in the pathogenesis of disseminated intravascular coagulation in ischemic heart disease].Kardiologiia, , Volume: 26, Issue:9, 1986
Lack of efficacy of nafazatrom, a novel anti-thrombotic compound, in patients with coronary artery disease.American heart journal, , Volume: 109, Issue:5 Pt 1, 1985
Cumulative inhibitory effect of low-dose aspirin on vascular prostacyclin and platelet thromboxane production in patients with atherosclerosis.Circulation, , Volume: 71, Issue:2, 1985
[Endogenous prostacycline and coronaropathy. Plasma levels of 6-keto-PGF1 alpha].Archives des maladies du coeur et des vaisseaux, , Volume: 78, Issue:8, 1985
Alteration of prostanoids in atherosclerosis.Seminars in thrombosis and hemostasis, , Volume: 11, Issue:4, 1985
Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog.The American journal of physiology, , Volume: 248, Issue:4 Pt 2, 1985
Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain.The American journal of physiology, , Volume: 249, Issue:1 Pt 2, 1985
A role for prostaglandins in reperfusion-induced myocardial injury?Advances in myocardiology, , Volume: 6, 1985
Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors.Circulation, , Volume: 72, Issue:2, 1985
Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery.Thrombosis research, , Aug-15, Volume: 39, Issue:4, 1985
Failure of percutaneous transluminal coronary angioplasty to stimulate platelet and prostaglandin activity.Catheterization and cardiovascular diagnosis, , Volume: 11, Issue:3, 1985
Prostacyclin and thromboxane levels during cardiac ischemia in dogs.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Cardiac prostaglandin synthesis in spontaneous and in effort angina.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Effects of selective thromboxane synthetase inhibitor OKY-046 on plasma prostaglandins in patients with coronary artery disease during exercise.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Plasma thromboxane B2, 6-keto PGF1 alpha and cyclic nucleotides levels as related to treadmill exercise test in patients with ischemic heart disease.Japanese circulation journal, , Volume: 49, Issue:1, 1985
Failure of myocardial ischemia to increase pulmonary microvascular permeability in dogs.Journal of applied physiology: respiratory, environmental and exercise physiology, , Volume: 56, Issue:3, 1984
The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds.Journal of molecular and cellular cardiology, , Volume: 16, Issue:1, 1984
Effects of mild physical exercise on serum lipoproteins and metabolites of arachidonic acid: a controlled randomised trial in middle aged men.British medical journal (Clinical research ed.), , Feb-25, Volume: 288, Issue:6417, 1984
Reduction of prostacyclin synthesis as a possible cause of transient flow reduction in a partially constricted canine coronary artery.Journal of molecular and cellular cardiology, , Volume: 16, Issue:12, 1984
Evidence for isosorbide dinitrate (ISDN) promoting effect on prostacyclin release by the lung and prostacyclin implication in ISDN-induced inhibition of platelet aggregation in humans.Prostaglandins, leukotrienes, and medicine, , Volume: 16, Issue:3, 1984
Acute systemic and coronary hemodynamic and serologic responses to cigarette smoking in long-term smokers with atherosclerotic coronary artery disease.Journal of the American College of Cardiology, , Volume: 4, Issue:5, 1984
The effects of timolol on arrhythmias and prostanoid release during canine myocardial ischaemia and reperfusion.British journal of pharmacology, , Volume: 81, Issue:4, 1984
Cardioprotective actions of pentoxifylline in an animal model of acute myocardial ischaemia.British journal of pharmacology, , Volume: 81, Issue:4, 1984
Cyclic nucleotides, prostaglandins, and ischemic heart disease.Advances in cyclic nucleotide and protein phosphorylation research, , Volume: 17, 1984
Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries.Circulation, , Volume: 69, Issue:6, 1984
[Cellular mechanism of action of molsidomine. Bioinduction of prostacyclin].Annales de cardiologie et d'angeiologie, , Volume: 32, Issue:8, 1983
Release of prostacyclin into the coronary venous blood in patients with coronary arterial disease.Advances in myocardiology, , Volume: 4, 1983
The significance of platelet-vessel wall prostaglandin equilibrium during exercise-induced stress.American heart journal, , Volume: 105, Issue:6, 1983
Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Release of adenosine and prostacyclin from ischemic human hearts.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Effects of selective thromboxane synthetase inhibitor and indomethacin on prostacyclin and thromboxane A2 from ischemic canine heart.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog.Cardiovascular research, , Volume: 17, Issue:3, 1983
Changes of plasma 6-keto-PGF1 alpha and thromboxane B2 levels and platelet aggregation after tourniquet ischemia on the upper limb in normal subjects and patients with ischemic heart disease.Japanese circulation journal, , Volume: 46, Issue:7, 1982
Severe intracoronary thromboxane release preceding acute coronary artery occlusion.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:6, 1982
Thromboxane and prostacyclin changes during cardiopulmonary bypass with and without pulsatile flow.The Journal of thoracic and cardiovascular surgery, , Volume: 84, Issue:2, 1982
Prostacyclin from the uterus and woman's cardiovascular advantage.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:5, 1982
Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease.The New England journal of medicine, , Mar-19, Volume: 304, Issue:12, 1981
Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2.Prostaglandins and medicine, , Volume: 6, Issue:3, 1981
Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias.Nature, , May-28, Volume: 291, Issue:5813, 1981
Laser endarterectomy: a comparison of thrombotic potential following CO2 laser vs surgical endarterectomy.Stroke, , Volume: 17, Issue:2
The effects of dietary mackerel oil on plasma and cell membrane lipids, on hemodynamics and cardiac arrhythmias during recurrent acute ischemia in the pig.Basic research in cardiology, , Volume: 81, Issue:6
Effect of the ultrashort-acting beta-blocker Brevibloc on free-radical-mediated injuries during the early reperfusion state.Basic research in cardiology, , Volume: 86, Issue:5
Effect of angiotensin II infusion on a prostaglandin I2-metabolite and on left ventricular function.Basic research in cardiology, , Volume: 81, Issue:3
Experimental coronary artery thrombosis in the absence of thromboxane A2 synthesis: evidence for alternate pathways for coronary thrombosis.Journal of cardiovascular pharmacology, , Volume: 7, Issue:1
Protective effect of a novel thromboxane synthetase inhibitor, CV-4151, on myocardial damage due to coronary occlusion and reperfusion in the hearts of anesthetized dogs.Journal of cardiovascular pharmacology, , Volume: 8, Issue:4
Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs.Coronary artery disease, , Volume: 15, Issue:1, 2004
Endothelial cell activation by endotoxin involves superoxide/NO-mediated nitration of prostacyclin synthase and thromboxane receptor stimulation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, , Volume: 17, Issue:8, 2003
Cyclosporine-induced coronary artery constriction--dissociation between thromboxane release and coronary vasospasm.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , Volume: 18, Issue:4, 1999
Increased serotonin release across the coronary bed during a nonischemic interval in patients with vasospastic angina.Clinical cardiology, , Volume: 19, Issue:6, 1996
Alcohol and coronary spasm.Angiology, , Volume: 45, Issue:3, 1994
Thromboxane release during percutaneous transluminal coronary angioplasty.American heart journal, , Volume: 111, Issue:1, 1986
Development of quantitative analysis of plasma thromboxane B2 by gas chromatography-mass spectrometry.Japanese circulation journal, , Volume: 49, Issue:3, 1985
[Plasma levels of thromboxane B2 and 6-keto PGF1 alpha in patients with variant angina].Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, , Volume: 74, Issue:6, 1985
Coronary spasm, prostaglandin and HLA factors.Japanese circulation journal, , Volume: 49, Issue:1, 1985
[Thromboxane analyses in patients with chronic inflammatory bowel diseases].Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, , Volume: 46, Issue:4, 1986
[Arachidonic acid metabolism in inflammatory bowel disease--with reference to cyclooxygenase products].Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, , Volume: 82, Issue:10, 1985
Imbalance of prostacyclin and thromboxane synthesis in Crohn's disease.Gut, , Volume: 24, Issue:10, 1983
Prostanoid synthesis by cultured peripheral blood mononuclear cells in inflammatory diseases of the bowel.Gastroenterology, , Volume: 82, Issue:4, 1982
Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis.European journal of pharmacology, , Nov-28, Volume: 505, Issue:1-3, 2004
[Eicosanoic acid levels in children with atopic dermatitis].Pediatriia, , Issue:10, 1991
Release of mediators from human gastric mucosa and blood in adverse reactions to benzoate.International archives of allergy and applied immunology, , Volume: 96, Issue:2, 1991
[The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses].Vestnik dermatologii i venerologii, , Issue:1, 1989
Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins.The British journal of dermatology, , Volume: 117, Issue:1, 1987
A case of familial central diabetes insipidus: the response of urinary prostaglandins to 1-deamino-8-D-arginine vasopressin.The Journal of urology, , Volume: 152, Issue:1, 1994
Excretion of 6-keto-PGF1 alpha and PGE2 in rats with hereditary hypothalamic diabetes insipidus.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:1, 1983
PGE2 and 6-keto-PGF1 alpha excretion in Brattleboro rats with hereditary hypothalamic diabetes insipidus.Archives internationales de pharmacodynamie et de therapie, , Volume: 266, Issue:1, 1983
Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic.Prostaglandins & other lipid mediators, , Volume: 58, Issue:5-6, 1999
Elevated renal endothelin-I clearance and mRNA levels associated with albuminuria and nephropathy in non-insulin-dependent diabetes mellitus: studies in obese fa/fa Zucker rats.Clinical science (London, England : 1979), , Volume: 93, Issue:6, 1997
Blood glucose and diabetic retinopathy.BMJ (Clinical research ed.), , May-09, Volume: 304, Issue:6836, 1992
Modification of membrane properties of erythrocytes by PGI2.Thrombosis research, , Jun-15, Volume: 54, Issue:6, 1989
In vivo measurement of thromboxane B2 and 6-keto-prostaglandin F1 alpha in humans in response to a standardized vascular injury and the influence of aspirin.Circulation, , Volume: 79, Issue:1, 1989
Radioimmunoassay of thromboxane B2 and its preliminary applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:1, 1988
Urinary metabolites of thromboxane and prostacyclin in diabetes mellitus.Acta endocrinologica, , Volume: 118, Issue:2, 1988
Plasma thromboxane and prostacyclin metabolite ratio in atherosclerosis and diabetes mellitus.Thrombosis research, , Aug-15, Volume: 47, Issue:4, 1987
Reevaluation of circulating prostacyclin and thromboxane in diabetes.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:2, 1987
Abnormal diurnal urinary sodium and water excretion in diabetic autonomic neuropathy.Clinical science (London, England : 1979), , Volume: 73, Issue:3, 1987
Stability of prostacyclin in human and rabbit whole blood and plasma.Thrombosis research, , Aug-15, Volume: 43, Issue:4, 1986
Release of prostacyclin after erythrocyte adhesion to cultured vascular endothelium.The Journal of laboratory and clinical medicine, , Volume: 107, Issue:3, 1986
Low plasma renin activity in diabetes. Relation to urine prostaglandin excretion.Diabetes, , Volume: 34, Issue:2, 1985
Prostacyclin synthetase activity in diabetic human venous tissue.Surgery, , Volume: 96, Issue:2, 1984
6-Keto prostaglandin F1 alpha production in endothelial-cell cultures in response to normal and diabetic human serum.Bioscience reports, , Volume: 3, Issue:1, 1983
Production of 6-oxo-prostaglandin F1 alpha and prostaglandin E2 by isolated glomeruli from normal and diabetic rats.British medical journal (Clinical research ed.), , Apr-24, Volume: 284, Issue:6324, 1982
Prostacyclin and thromboxane in diabetes.British medical journal (Clinical research ed.), , Oct-31, Volume: 283, Issue:6300, 1981
In-vitro venous prostacyclin production, plasma 6-keto-prostaglandin F1 alpha concentrations, and diabetic retinopathy.British medical journal (Clinical research ed.), , Apr-18, Volume: 282, Issue:6272, 1981
Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes.Clinical endocrinology, , Volume: 15, Issue:5, 1981
Altered synthesis of prostaglandins in platelet and aorta from spontaneously diabetic Wistar rats.Biochemical medicine, , Volume: 23, Issue:2, 1980
Effect of diabetic sera on the conversion of eicosapentaenoic acid (EPA) to prostaglandin I3 by cultured bovine aortic endothelial cells.Prostaglandins, , Volume: 50, Issue:5-6
Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats.Journal of ethnopharmacology, , Nov-25, Volume: 150, Issue:2, 2013
Depression of cyclooxygenase-2 induction in aortas of rats with type 1 and type 2 diabetes mellitus.European journal of pharmacology, , Oct-24, Volume: 595, Issue:1-3, 2008
The hemodynamic abnormalities in short-term insulin deficiency: the role of prostaglandin inhibition.Diabetes, , Volume: 45, Issue:5, 1996
Cyclosporin reduces renal prostanoid excretion in type 1 diabetic patients.Acta diabetologica, , Volume: 29, Issue:1, 1992
Effects of thromboxane synthesis inhibitor triflusal on renal hemodynamics in microalbuminuric diabetic patients.Diabetes care, , Volume: 13, Issue:11, 1990
Stimulation of prostacyclin synthesis by physical exercise in type I diabetes.Diabetes care, , Volume: 12, Issue:9, 1989
Evidence against a role for prostaglandins in sustaining renal hyperfiltration in type 1 diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association, , Volume: 6, Issue:6, 1989
Glomerular hyperfiltration and urinary prostaglandins in type 1 diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association, , Volume: 6, Issue:3, 1989
Renal hemodynamics and urinary excretion of 6-keto-prostaglandin F1 alpha and thromboxane B2 in newly diagnosed type I diabetic patients.Diabetes, , Volume: 37, Issue:8, 1988
Thromboxane biosynthesis and platelet function in type I diabetes mellitus.The New England journal of medicine, , Jul-28, Volume: 319, Issue:4, 1988
Effects of purified fish oil on platelet lipids and function in diabetic women.Clinica chimica acta; international journal of clinical chemistry, , May-15, Volume: 164, Issue:3, 1987
Thromboxane and 6-oxo-PGF1 alpha in the plasma of patients with diabetes type I and II.Progress in clinical and biological research, , Volume: 242, 1987
Plasma 6-keto-PGF1 alpha, thromboxane B2 and PGE2 in type 1 (insulin-dependent) diabetic patients during exercise.Diabetologia, , Volume: 30, Issue:7, 1987
Plasma prostaglandins: 6-keto-PGF1 alpha, TXB2 and PGE2 in juvenile-onset diabetes determined by high-pressure liquid chromatography and radio-immunoassay.Prostaglandins, leukotrienes, and medicine, , Volume: 22, Issue:3, 1986
Essential fatty acids in diabetes and systemic lupus erythematosus (SLE) patients.Biochemical and biophysical research communications, , Apr-30, Volume: 128, Issue:2, 1985
Influence of glucose, insulin and sera from diabetic patients on the prostacyclin synthesis in vitro in cultured human endothelial cells.Diabetologia, , Volume: 28, Issue:9, 1985
[Changes in circulatory prostacyclin in diabetics].Zhonghua nei ke za zhi, , Volume: 24, Issue:9, 1985
Prostacyclin and thromboxane in diabetic children.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:3, 1983
Normal plasma thromboxane B2 (TXB2) and 6-keto-PGF1 alpha levels in childhood diabetes.Prostaglandins, leukotrienes, and medicine, , Volume: 12, Issue:4, 1983
Sperm function and structure and seminal plasma prostanoid concentrations in men with IDDM.Diabetes care, , Volume: 12, Issue:10
Subclinical exocrine pancreatic derangement in human diabetic patients evaluated from pure pancreatic juice.Journal of diabetes and its complications, , Volume: 9, Issue:2
[The content of stable forms of prostacyclin I2 and thromboxane A2 in the blood plasma in diabetic angiopathies].Problemy endokrinologii, , Volume: 37, Issue:4
No effects of atorvastatin (10 mg/d or 80 mg/d) on nitric oxide, prostacyclin, thromboxane and oxidative stress in type 2 diabetes mellitus patients of the DALI study.Pharmacological research, , Volume: 94, 2015
Vasoconstrictor role of cyclooxygenase-1-mediated prostacyclin synthesis in non-insulin-dependent diabetic mice induced by high-fat diet and streptozotocin.American journal of physiology. Heart and circulatory physiology, , Aug-01, Volume: 307, Issue:3, 2014
Toll-like receptor 4 mutation protects obese mice against endothelial dysfunction by decreasing NADPH oxidase isoforms 1 and 4.Arteriosclerosis, thrombosis, and vascular biology, , Volume: 33, Issue:4, 2013
[Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 47, Issue:4, 2012
Depression of cyclooxygenase-2 induction in aortas of rats with type 1 and type 2 diabetes mellitus.European journal of pharmacology, , Oct-24, Volume: 595, Issue:1-3, 2008
[Relationship between syndrome differentiation of traditional Chinese medicine and vascular endothelial function in patients with diabetic arterial occlusion of lower extremities].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 5, Issue:6, 2007
Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II.Life sciences, , Oct-08, Volume: 75, Issue:21, 2004
[Characteristic changes of vascular tension factors in diabetic arterial occlusion of lower extremities].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 24, Issue:9, 2004
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects.Thrombosis research, , Nov-01, Volume: 108, Issue:2-3, 2002
Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications".Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 67, Issue:5, 2002
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 65, Issue:4, 2001
Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:5, 2000
Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes.Life sciences, , Volume: 66, Issue:5, 2000
High glucose levels modulate eicosanoid production in uterine and placental tissue from non-insulin-dependent diabetic rats during late pregnancy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 58, Issue:6, 1998
Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 59, Issue:5, 1998
Prostanoid production in the umbilicoplacental arterial tree relative to impaired glucose tolerance.Early human development, , Jan-09, Volume: 50, Issue:2, 1998
Effect of gemfibrozil on serum levels of prostacyclin and precursor fatty acids in hyperlipidemic patients with Type 2 diabetes.Diabetes research and clinical practice, , Volume: 42, Issue:3, 1998
Difference in serum-induced prostacyclin production by cultured aortic and capillary endothelial cells.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:1, 1997
Eicosanoid production by placental and amnion tissues from control and non-insulin-dependent diabetic rats. Influence of oxytocin in the incubating medium.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:6, 1997
Elevated renal endothelin-I clearance and mRNA levels associated with albuminuria and nephropathy in non-insulin-dependent diabetes mellitus: studies in obese fa/fa Zucker rats.Clinical science (London, England : 1979), , Volume: 93, Issue:6, 1997
Effect of captopril on renal hemodynamics and renal prostaglandins in early type II diabetic patients with normo-or microalbuminuria.Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, , Volume: 11, Issue:3, 1996
[Effects of tangshenkang capsule on diabetic nephropathy].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:7, 1996
[Study on relationship of lipid peroxide in coronary heart disease with and without diabetes].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:1, 1996
Analysis of the thromboxane/prostacyclin balance in human urine by gas chromatography/selected ion monitoring: abnormalities in diabetics.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 54, Issue:6, 1996
Improvement in blood flow and diabetic neuropathy by thromboxane A2 dual blocker KDI-792.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:2, 1995
Eicosanoid production and phospholipase A2 activity in uterine tissue from castrated rats with non-insulin dependent diabetes mellitus.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:5, 1995
Platelet volume and urinary prostanoid metabolites in non-insulin-dependent diabetes mellitus.Journal of atherosclerosis and thrombosis, , Volume: 1, Issue:2, 1994
Partial purification of serum prostacyclin stimulatory activity by heparin-agarose column; abnormality detected in diabetics.Diabetes research and clinical practice, , Volume: 16, Issue:2, 1992
[The effect of eicosapentaenoic acid enriched marine oil on the platelet function in hypercoagulable state].Zhonghua nei ke za zhi, , Volume: 29, Issue:7, 1990
Effects of vitamin E administration on platelet function in diabetes mellitus.Diabetes research (Edinburgh, Scotland), , Volume: 14, Issue:1, 1990
Effects of captopril on urinary excretion of albumin and prostaglandins in patients with diabetic nephropathy.Diabetes research (Edinburgh, Scotland), , Volume: 13, Issue:3, 1990
Involvement of prostaglandins in the action of captopril in type II diabetic patients.Experimental and clinical endocrinology, , Volume: 93, Issue:1, 1989
Abnormality in prostacyclin-stimulatory activity in sera from diabetics.Metabolism: clinical and experimental, , Volume: 38, Issue:9, 1989
[Evaluation of plasma 6-keto-prostaglandin F1 alpha and thromboxane B2 in diabetic neuropathy].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 63, Issue:1, 1987
Thromboxane and 6-oxo-PGF1 alpha in the plasma of patients with diabetes type I and II.Progress in clinical and biological research, , Volume: 242, 1987
Reduced serum-stimulatory activity on prostacyclin production by cultured aortic endothelial cells in diabetes mellitus.Haemostasis, , Volume: 16, Issue:6, 1986
Platelet and endothelial function tests during metformin treatment in diabetes mellitus (short communication).Hormone and metabolic research. Supplement series, , Volume: 15, 1985
[Changes in circulatory prostacyclin in diabetics].Zhonghua nei ke za zhi, , Volume: 24, Issue:9, 1985
Prostacyclin and thromboxane in non-insulin dependent diabetes: the chlorpropamide alcohol flush reaction revisited.Clinical science (London, England : 1979), , Volume: 67, Issue:6, 1984
Thromboxane, prostacyclin, beta-thromboglobin, and diabetes mellitus.Clinical therapeutics, , Volume: 6, Issue:5, 1984
[The content of stable forms of prostacyclin I2 and thromboxane A2 in the blood plasma in diabetic angiopathies].Problemy endokrinologii, , Volume: 37, Issue:4
Long-term feeding of corn oil, beef tallow, or menhaden oil and eicosanoid levels in BHE/cdb rats.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 8, Issue:6
Subclinical exocrine pancreatic derangement in human diabetic patients evaluated from pure pancreatic juice.Journal of diabetes and its complications, , Volume: 9, Issue:2
Effects of eicosapentaenoic acid (EPA) on prostacyclin production in diabetics: GC/MS analysis of PGI2 and PGI3 levels.Methods and findings in experimental and clinical pharmacology, , Volume: 19, Issue:6
Effects of cilostazol, a phosphodiesterase inhibitor, on urinary excretion of albumin and prostaglandins in non-insulin-dependent diabetic patients.Diabetes research and clinical practice, , Volume: 22, Issue:1
Prostaglandins and diabetic nephropathy.Journal of diabetes and its complications, , Volume: 9, Issue:4
Nitric oxide-cGMP and prostacyclin-cAMP pathways in patients with type II diabetes and different types of retinopathy.Pathophysiology of haemostasis and thrombosis, , Volume: 32, Issue:1
Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat.Journal of diabetes and its complications, , Volume: 13, Issue:4
Progression of carotid atherosclerosis and the role of endothelin in diabetic patients.Research communications in molecular pathology and pharmacology, , Volume: 108, Issue:1-2
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
[Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 1, Issue:2, 2003
Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 65, Issue:4, 2001
[Effect of Astragalus injection on platelet function and plasma endothelin in patients with early stage diabetic nephropathy].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 21, Issue:4, 2001
[Comparative study on effect of Panax notoginseng and ticlid in treating early diabetic nephropathy].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:12, 1998
[Effects of tangshenkang capsule on diabetic nephropathy].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:7, 1996
Studies on the impact of dietary fat composition on proteinuria in diabetic rats.Diabetes research and clinical practice, , Volume: 33, Issue:1, 1996
Effect of eicosapentaenoic acid ethyl ester on albuminuria in streptozotocin-induced diabetic rats.Journal of nutritional science and vitaminology, , Volume: 40, Issue:1, 1994
Effects of captopril on urinary excretion of albumin and prostaglandins in patients with diabetic nephropathy.Diabetes research (Edinburgh, Scotland), , Volume: 13, Issue:3, 1990
Effects of a selective thromboxane synthetase inhibitor OKY-046 on experimental diabetic nephropathy.Nephron, , Volume: 56, Issue:3, 1990
Glomerular prostaglandin production in diabetic rats with renovascular hypertension.Kidney international, , Volume: 33, Issue:6, 1988
Glomerular and hormonal responses to dietary protein intake in human renal disease.The American journal of physiology, , Volume: 253, Issue:6 Pt 2, 1987
Prostaglandins and diabetic nephropathy.Journal of diabetes and its complications, , Volume: 9, Issue:4
Effects of cilostazol, a phosphodiesterase inhibitor, on urinary excretion of albumin and prostaglandins in non-insulin-dependent diabetic patients.Diabetes research and clinical practice, , Volume: 22, Issue:1
Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 65, Issue:4, 2001
Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat.The Journal of clinical investigation, , Apr-15, Volume: 97, Issue:8, 1996
Effects of beraprost sodium and insulin on the electroretinogram, nerve conduction, and nerve blood flow in rats with streptozotocin-induced diabetes.Diabetes, , Volume: 45, Issue:3, 1996
Improvement in blood flow and diabetic neuropathy by thromboxane A2 dual blocker KDI-792.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:2, 1995
Hemodynamic effects of cilostazol on peripheral artery in patients with diabetic neuropathy.Arzneimittel-Forschung, , Volume: 42, Issue:4, 1992
[Evaluation of plasma 6-keto-prostaglandin F1 alpha and thromboxane B2 in diabetic neuropathy].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 63, Issue:1, 1987
Abnormal diurnal urinary sodium and water excretion in diabetic autonomic neuropathy.Clinical science (London, England : 1979), , Volume: 73, Issue:3, 1987
Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 367, Issue:2, 2003
Effect of DT-TX 30, a combined thromboxane synthase inhibitor and thromboxane receptor antagonist, on retinal vascularity in experimental diabetes mellitus.Thrombosis research, , Feb-01, Volume: 97, Issue:3, 2000
Effects of beraprost sodium and insulin on the electroretinogram, nerve conduction, and nerve blood flow in rats with streptozotocin-induced diabetes.Diabetes, , Volume: 45, Issue:3, 1996
Blood glucose and diabetic retinopathy.BMJ (Clinical research ed.), , May-09, Volume: 304, Issue:6836, 1992
Effects of captopril on urinary excretion of albumin and prostaglandins in patients with diabetic nephropathy.Diabetes research (Edinburgh, Scotland), , Volume: 13, Issue:3, 1990
Reevaluation of circulating prostacyclin and thromboxane in diabetes.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:2, 1987
Prostacyclin production by human endothelial cells cultured in diabetic serum.Diabete & metabolisme, , Volume: 8, Issue:4, 1982
In-vitro venous prostacyclin production, plasma 6-keto-prostaglandin F1 alpha concentrations, and diabetic retinopathy.British medical journal (Clinical research ed.), , Apr-18, Volume: 282, Issue:6272, 1981
Factors affecting the production of prostacyclin in man.Progress in lipid research, , Volume: 20, 1981
Forearm ischaemia as a test of prostacyclin production: studies in normal subjects and in patients with diabetes mellitus.Prostaglandins and medicine, , Volume: 6, Issue:6, 1981
Nitric oxide-cGMP and prostacyclin-cAMP pathways in patients with type II diabetes and different types of retinopathy.Pathophysiology of haemostasis and thrombosis, , Volume: 32, Issue:1
Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet.Journal of clinical pharmacology, , Volume: 47, Issue:12, 2007
Prostacyclin in diarrhoea-associated haemolytic uraemic syndrome.Pediatric nephrology (Berlin, Germany), , Volume: 7, Issue:5, 1993
Role of activated platelets in endotoxin-induced DIC in rats.Thrombosis research, , Aug-15, Volume: 59, Issue:4, 1990
Hypercoagulable state and hemorrhage in acute leukemias.Chinese medical journal, , Volume: 101, Issue:6, 1988
Mechanism of the therapeutic effect of anisodamine in disseminated intravascular coagulation: study of platelet adhesion and aggregation, malondialdehyde, thromboxane B2, 6-keto-prostaglandin F1 alpha, and microcirculation.Experimental hematology, , Volume: 15, Issue:1, 1987
[Disorders in the status of the vessel-thrombocyte and plasma links of the hemostatic system in the pathogenesis of disseminated intravascular coagulation in ischemic heart disease].Kardiologiia, , Volume: 26, Issue:9, 1986
Implications for thromboxane A2 in the pathogenesis of endotoxic shock.Advances in shock research, , Volume: 6, 1981
Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys.Prostaglandins & other lipid mediators, , Volume: 85, Issue:3-4, 2008
In utero remodeling of the fetal lamb ductus arteriosus: the role of antenatal indomethacin and avascular zone thickness on vasa vasorum proliferation, neointima formation, and cell death.Circulation, , Apr-03, Volume: 103, Issue:13, 2001
Prostacyclin concentrations and transitional circulation in preterm infants requiring mechanical ventilation.Archives of disease in childhood. Fetal and neonatal edition, , Volume: 80, Issue:1, 1999
Distribution of prostacyclin synthase, 6-keto-prostaglandin F1 alpha, and 15-hydroxy-prostaglandin dehydrogenase in the normal and persistent ductus arteriosus of the dog.The American journal of pathology, , Volume: 135, Issue:5, 1989
Endogenous dilator prostaglandins in congenital heart disease.Pediatric cardiology, , Volume: 8, Issue:3, 1987
[New aspects on the pathogenesis of patent ductus arteriosus in premature infants].Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, , Volume: 134, Issue:7, 1986
Systemic production of prostacyclin and thromboxane A2 does not correlate with patency of the ductus arteriosus in very low birth weight infants.The Journal of pediatrics, , Volume: 108, Issue:6, 1986
Prostaglandin levels: predictors of indomethacin responsiveness.Pediatric cardiology, , Volume: 7, Issue:2, 1986
The silent ductus: its precursors and its aftermath.Pediatric cardiology, , Volume: 7, Issue:3, 1986
Prostaglandins and echocardiography in the assessment of patent ductus arteriosus.Critical care medicine, , Volume: 14, Issue:5, 1986
Early administration of indomethacin to preterm infants.Archives of disease in childhood, , Volume: 61, Issue:3, 1986
Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants.The Journal of pediatrics, , Volume: 107, Issue:6, 1985
Urinary excretion rates of 6-keto-PGF1 alpha in preterm infants recovering from respiratory distress with and without patent ductus arteriosus.Pediatric research, , Volume: 18, Issue:6, 1984
On the biochemical background of cysteamine-induced duodenal ulceration in the rat.Scandinavian journal of gastroenterology, , Volume: 28, Issue:5, 1993
The effect of prostacyclin and its analogues on cysteamine-induced duodenal ulceration of rats.Scandinavian journal of gastroenterology. Supplement, , Volume: 167, 1989
Potent CNS action of calcitonin to inhibit cysteamine-induced duodenal ulcers in rat.Life sciences, , Aug-03, Volume: 41, Issue:5, 1987
Role of endogenous gastric prostanoids in the pathogenesis and therapy of duodenal ulcer.Gastroenterology, , Volume: 90, Issue:4, 1986
Pathogenic mechanisms involved in mepirizole-induced duodenal damage in the rat.Japanese journal of pharmacology, , Volume: 42, Issue:3, 1986
Effect of cimetidine on human gastric and duodenal prostanoid synthesis.Scandinavian journal of gastroenterology, , Volume: 19, Issue:4, 1984
Prostanoid synthesis by cultured gastric and duodenal mucosa: Possible role in the pathogenesis of duodenal ulcer.Scandinavian journal of gastroenterology, , Volume: 18, Issue:8, 1983
[Effect of electroacupuncture at different acupoints on plasma TXB2 and 6-keto-PGF(1alpha), contents in dysmenorrhea rats].Zhen ci yan jiu = Acupuncture research, , Volume: 36, Issue:5, 2011
[Randomized controlled study on ear-electroacupuncture treatment of endometriosis-induced dysmenorrhea in patients].Zhen ci yan jiu = Acupuncture research, , Volume: 34, Issue:3, 2009
Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea.Prostaglandins & other lipid mediators, , Volume: 83, Issue:1-2, 2007
[Studies on prostaglandin production relating to the mechanism of dysmenorrhea in endometriosis].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 70, Issue:1, 1994
Correlation between dysmenorrheic severity and prostaglandin production in women with endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 46, Issue:2, 1992
Prostaglandins: PGF2 alpha, PGE2, 6-keto-PGF1 alpha and TXB2 serum levels in dysmenorrheic adolescents before, during and after treatment with oral contraceptives.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 36, Issue:3, 1990
Primary dysmenorrhoea: the importance of both prostaglandins E2 and F2 alpha.British journal of obstetrics and gynaecology, , Volume: 90, Issue:12, 1983
Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats.Critical care medicine, , Volume: 34, Issue:7, 2006
[Endothelial cell damage induced in vitro by subeschar tissue fluid].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 15, Issue:5, 1999
Prostaglandin levels of primary bone tumor tissues correlate with peritumoral edema demonstrated by magnetic resonance imaging.Cancer, , Jan-15, Volume: 79, Issue:2, 1997
Inhibition of carrageenin-induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2.British journal of pharmacology, , Volume: 114, Issue:3, 1995
Modulation by nitric oxide of prostaglandin biosynthesis in the rat.British journal of pharmacology, , Volume: 114, Issue:2, 1995
Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat. Differentiation of effects between nabumetone and etodolac.Digestive diseases and sciences, , Volume: 39, Issue:3, 1994
Anti-inflammatory activities of Ph CL28A in rats in vivo.European journal of pharmacology, , Feb-09, Volume: 231, Issue:2, 1993
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.Annals of surgery, , Volume: 212, Issue:6, 1990
Inhibition of thromboxane synthetase accentuates hemodynamic instability and burn edema in the anesthetized sheep model.Surgery, , Volume: 105, Issue:5, 1989
Indomethacin and dexamethasone treatment in experimental neoplastic spinal cord compression: Part 2. Effect on edema and prostaglandin synthesis.Neurosurgery, , Volume: 22, Issue:2, 1988
Topical ibuprofen decreases early postburn edema.Surgery, , Volume: 102, Issue:5, 1987
Thromboxane and 5-HETE increase after experimental spinal cord injury in rabbits.Central nervous system trauma : journal of the American Paralysis Association, , Volume: 4, Issue:2, 1987
Increased thromboxane level in experimental spinal cord injury.Journal of the neurological sciences, , Volume: 74, Issue:2-3, 1986
Platelet-activating factor causes pulmonary vasoconstriction and edema via platelet-independent leukotriene formation.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 12, 1983
Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon.Prostaglandins and medicine, , Volume: 7, Issue:5, 1981
Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet.Journal of clinical pharmacology, , Volume: 47, Issue:12, 2007
TP receptors regulate renal hemodynamics during angiotensin II slow pressor response.American journal of physiology. Renal physiology, , Volume: 287, Issue:4, 2004
Pathobiochemical effects of graded magnesium deficiency in rats.Zeitschrift fur Ernahrungswissenschaft, , Volume: 37 Suppl 1, 1998
Effects of the angiotensin converting enzyme (ACE) inhibitor, captopril, on the cardiovascular, endocrine, and renal responses to furosemide in conscious lambs.Canadian journal of physiology and pharmacology, , Volume: 75, Issue:4, 1997
Effect of acetylsalicylic acid, paracetamol, caffeine and a combination of these substances on the renal prostaglandin E2, 6-keto-prostaglandin F1 alpha, water, creatinine and electrolyte excretion of the rat.Arzneimittel-Forschung, , Volume: 46, Issue:5, 1996
Association between the natriuretic action of angiotensin-(1-7) and selective stimulation of renal prostaglandin I2 release.Hypertension (Dallas, Tex. : 1979), , Volume: 25, Issue:6, 1995
Effect of captopril cardioplegia on renin-angiotensin system, prostaglandins, free radicals and electrolytes in the isolated hypothermic ischemic and reperfusion rabbit hearts.Chinese medical journal, , Volume: 106, Issue:12, 1993
Study of mechanisms of glucocorticoid hypertension in rats: endothelial related changes and their amelioration by dietary fish oils.British journal of pharmacology, , Volume: 106, Issue:2, 1992
Blood pressure and vascular reactivity changes in spontaneously hypertensive rats fed fish oil.British journal of pharmacology, , Volume: 102, Issue:4, 1991
Influence of renal insufficiency on the pharmacokinetics of cicletanine and its effects on the urinary excretion of electrolytes and prostanoids.British journal of clinical pharmacology, , Volume: 25, Issue:3, 1988
Dietary suppression of prostaglandin synthesis does not accelerate DOCA/salt hypertension in rats.Clinical and experimental pharmacology & physiology, , Volume: 14, Issue:6, 1987
Renin-angiotensin system and glomerular prostaglandins in early nephrotoxicity of ciclosporin.Contributions to nephrology, , Volume: 51, 1986
Effects of low-dose aspirin on responses to furosemide.Journal of clinical pharmacology, , Volume: 26, Issue:2, 1986
Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man.British journal of clinical pharmacology, , Volume: 21, Issue:3, 1986
Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans.Prostaglandins, leukotrienes, and medicine, , Volume: 23, Issue:2-3, 1986
Effect of prostaglandin blockers on ascites fluid in pancreatitis.Surgery, , Volume: 98, Issue:3, 1985
Plasma levels of 6-keto-prostaglandin F1 alpha in normotensive subjects and patients with essential hypertension.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:4, 1983
Stimulation of renal prostaglandins by pressor hormones in man: comparison of prostaglandin E2 and prostacyclin (6 keto prostaglandin F1 alpha).The Journal of clinical endocrinology and metabolism, , Volume: 56, Issue:6, 1983
Platelets are an unindicted culprit in the development of endometriosis: clinical and experimental evidence.Human reproduction (Oxford, England), , Volume: 30, Issue:4, 2015
[Targeted interruption of COX-2 gene by siRNA inhibits the expression of VEGF, MMP-9, the activity of COX-2 and stimulates the apoptosis in eutopic, ectopic endometrial stromal cells of women with endometriosis].Zhonghua fu chan ke za zhi, , Volume: 50, Issue:10, 2015
[Randomized controlled study on ear-electroacupuncture treatment of endometriosis-induced dysmenorrhea in patients].Zhen ci yan jiu = Acupuncture research, , Volume: 34, Issue:3, 2009
Endometriosis treated by the method of resolving blood stasis to eliminate obstruction in the lower-jiao.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 18, Issue:1, 1998
PGE2 and PGF2 alpha release by human peritoneal macrophages in endometriosis.Prostaglandins, , Volume: 51, Issue:1, 1996
[Studies on prostaglandin production relating to the mechanism of dysmenorrhea in endometriosis].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 70, Issue:1, 1994
Correlation between dysmenorrheic severity and prostaglandin production in women with endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 46, Issue:2, 1992
Eicosanoids production in endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:4, 1992
[Effects of gossypol and GnRHa on the prostaglandins contents of endometriotic cell and in situ].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:9, 1991
Prostaglandin and leukotriene concentration of the peritoneal fluid of endometriosis and other gynecologic disorders in the secretory phase.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Urinary excretion of prostacyclin and thromboxane degradation products in patients with ovarian malignancy: effect of cytostatic treatment.British journal of cancer, , Volume: 60, Issue:5, 1989
Peritoneal fluid eicosanoids in chronic pelvic pain.Prostaglandins, , Volume: 38, Issue:4, 1989
Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay.American journal of obstetrics and gynecology, , Volume: 154, Issue:6, 1986
[Prostanoids of the peritoneal fluid and sterility with or without pelvic lesions (endometriosis, postinfectious adhesions)].Pathologie-biologie, , Volume: 34, Issue:2, 1986
Peritoneal fluid volume, estrogen, progesterone, prostaglandin, and epidermal growth factor concentrations in patients with and without endometriosis.Obstetrics and gynecology, , Volume: 68, Issue:2, 1986
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Peritoneal fluid 6-keto prostaglandin F1 alpha levels in women with endometriosis.American journal of obstetrics and gynecology, , Aug-01, Volume: 152, Issue:7 Pt 1, 1985
Follicular fluid prostaglandins in endometriosis and ovarian hyperstimulation.Fertility and sterility, , Volume: 41, Issue:1, 1984
Peritoneal fluid 6-keto-prostaglandin F1 alpha, thromboxane B2 in endometriosis and unexplained infertility.Acta obstetricia et gynecologica Scandinavica. Supplement, , Volume: 123, 1984
Peritoneal fluid prostaglandins and prostanoids in women with endometriosis, chronic pelvic inflammatory disease, and pelvic pain.American journal of obstetrics and gynecology, , Feb-15, Volume: 148, Issue:4, 1984
Prostaglandins and endometriosis.Acta obstetricia et gynecologica Scandinavica. Supplement, , Volume: 113, 1983
Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis.American journal of obstetrics and gynecology, , Jun-15, Volume: 140, Issue:4, 1981
Fallopian tube prostaglandin production with and without endometriosis.International journal of fertility and menopausal studies, , Volume: 39, Issue:1
Effect of infrared irradiation on the recoverable levels of free arachidonic acid and prostaglandins in human forearm skin.The Journal of investigative dermatology, , Volume: 81, Issue:4, 1983
Increased concentrations of arachidonic acid, prostaglandins E2, D2, and 6-oxo-F1 alpha, and histamine in human skin following UVA irradiation.The Journal of investigative dermatology, , Volume: 80, Issue:6, 1983
Synthesis of prostacyclin and its effect on the contractile activity of the inflamed porcine uterus.Theriogenology, , Volume: 79, Issue:3, 2013
Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice.American journal of physiology. Renal physiology, , Volume: 293, Issue:4, 2007
Effect of indomethacin on peritoneal protein loss in a rabbit model of peritonitis.Kidney international, , Volume: 59, Issue:1, 2001
The effects of hyperoxia on the biosynthesis of cyclooxygenase products and haemodynamic response to nitric oxide synthase inhibition with L-NAME in endotoxaemic pigs.Journal of veterinary pharmacology and therapeutics, , Volume: 21, Issue:5, 1998
Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses.American journal of veterinary research, , Volume: 58, Issue:11, 1997
Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 77, Issue:3, 1994
A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model.Critical care medicine, , Volume: 21, Issue:12, 1993
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
Dietary selenium effects on milk eicosanoid concentration in dairy cows during coliform mastitis.Prostaglandins, , Volume: 42, Issue:4, 1991
Ibuprofen therapy in experimental porcine gram-negative septic shock.Resuscitation, , Volume: 22, Issue:1, 1991
[The observation of changes in plasma PGI2 and TXA2 levels and the therapeutic effect of tetramethylpyrazine in E. coli induced acute lung injury in rabbits].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 14, Issue:3, 1991
Effect of leukotriene inhibitor LY-171883 on the pulmonary response to Escherichia coli endotoxemia.Critical care medicine, , Volume: 18, Issue:2, 1990
Enterococcal sepsis and lung microvascular injury in sheep.Archives of surgery (Chicago, Ill. : 1960), , Volume: 125, Issue:4, 1990
Eicosanoids and the hemodynamic course of live Escherichia coli-induced sepsis in baboons.Circulatory shock, , Volume: 29, Issue:3, 1989
Hemodynamics, plasma eicosanoid concentrations, and plasma biochemical changes in calves given multiple injections of Escherichia coli endotoxin.American journal of veterinary research, , Volume: 49, Issue:1, 1988
Indomethacin, but not dazoxiben, reduced lung fluid filtration after E. coli infusion.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 64, Issue:6, 1988
Comparison of the postburn hyperdynamic state and changes in lung function (effect of wound bacterial content).Surgery, , Volume: 100, Issue:5, 1986
The pulmonary and systemic response to recurrent endotoxemia in the adult sheep.Surgery, , Volume: 100, Issue:5, 1986
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis.Annals of surgery, , Volume: 200, Issue:5, 1984
The development of a model of subacute lung injury after intra-abdominal infection.Surgery, , Volume: 96, Issue:2, 1984
Effects of a fish oil diet on pigs' cardiopulmonary response to bacteremia.JPEN. Journal of parenteral and enteral nutrition, , Volume: 15, Issue:2
The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy.Prostaglandins & other lipid mediators, , Volume: 95, Issue:1-4, 2011
Vasoactive mediator release by fetal endothelial cells in intrauterine growth restriction and preeclampsia.American journal of obstetrics and gynecology, , Volume: 184, Issue:3, 2001
[Study on relativity between oxygen free radical and thromboxane B2, 6-keto-PGF1 alpha during ligustrazine treatment of intrauterine growth retardation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:5, 1998
Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats.Biology of the neonate, , Volume: 72, Issue:3, 1997
Release of vasoactive agents during cordocentesis: differences between normally grown and growth-restricted fetuses.American journal of obstetrics and gynecology, , Volume: 175, Issue:3 Pt 1, 1996
Lack of association between Doppler velocimetry and synthesis of prostacyclin and thromboxane in umbilical cord vessels from growth retarded fetuses.Acta obstetricia et gynecologica Scandinavica, , Volume: 74, Issue:2, 1995
[Effect of trapidil in prevention of pre-eclampsia and fetal retardation].Zentralblatt fur Gynakologie, , Volume: 117, Issue:1, 1995
[Effect of 3,4-dihydroxyacetophenone treatment on intrauterine growth retardation].Zhonghua fu chan ke za zhi, , Volume: 28, Issue:6, 1993
Endotoxin-induced fetal growth retardation in the pregnant guinea pig.American journal of obstetrics and gynecology, , Volume: 168, Issue:2, 1993
[A trial of low-dose aspirin therapy in high-risk pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:7, 1992
Evidence that prostacyclin deficiency is a specific feature in preeclampsia.American journal of obstetrics and gynecology, , Mar-15, Volume: 148, Issue:6, 1984
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
Effect of IGF-I on placental thromboxane and prostacyclin release in severe intrauterine growth retardation.The Journal of maternal-fetal medicine, , Volume: 6, Issue:6
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.Journal of pharmacological sciences, , Volume: 130, Issue:2, 2016
Salicylate treatment in Kawasaki disease: high dose or low dose?European journal of pediatrics, , Volume: 150, Issue:9, 1991
Ibuprofen prevents Pasteurella hemolytica endotoxin-induced changes in plasma prostanoids and serotonin, and fever in sheep.Journal of veterinary pharmacology and therapeutics, , Volume: 8, Issue:4, 1985
Prostaglandin production by murine tumors as a predictor for therapeutic response to indomethacin.Cancer research, , Jun-01, Volume: 48, Issue:11, 1988
Dissociation between thromboxane generation and metastatic potential in cells from a murine fibrosarcoma. Studies with a selective thromboxane synthase inhibitor.International journal of cancer, , Apr-15, Volume: 39, Issue:4, 1987
Trans-10,cis-12-conjugated linoleic acid worsens renal pathology and alters cyclooxygenase derived oxylipins in obesity-associated nephropathy.The Journal of nutritional biochemistry, , Volume: 26, Issue:2, 2015
Prostaglandins in squamous cell carcinoma of the larynx: tumor and peritumor synthesis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Laser speckle contrast imaging for quantitative assessment of facial flushing during mesenteric traction syndrome in upper gastrointestinal surgery.Journal of clinical monitoring and computing, , Volume: 33, Issue:5, 2019
Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial.BMC surgery, , Aug-11, Volume: 17, Issue:1, 2017
Remifentanil increases the incidence of mesenteric traction syndrome: preliminary randomized controlled trial.Journal of anesthesia, , Volume: 24, Issue:5, 2010
Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1.European journal of pharmacology, , May-01, Volume: 536, Issue:3, 2006
Ibuprofen pretreatment inhibits prostacyclin release during abdominal exploration in aortic surgery.Anesthesiology, , Volume: 72, Issue:3, 1990
The role of prostacyclin in the mesenteric traction syndrome during anesthesia for abdominal aortic reconstructive surgery.Annals of surgery, , Volume: 209, Issue:3, 1989
Increased compliance of niceritrol treatment by addition of aspirin: relationship between changes in prostaglandins and skin flushing.International journal of clinical pharmacology, therapy, and toxicology, , Volume: 25, Issue:12, 1987
Prostacyclin and thromboxane in non-insulin dependent diabetes: the chlorpropamide alcohol flush reaction revisited.Clinical science (London, England : 1979), , Volume: 67, Issue:6, 1984
Synthetic pathways of gallbladder mucosal prostanoids: the role of cyclooxygenase-1 and 2.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 60, Issue:2, 1999
[Measurement of prostaglandins in human bile juice].Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, , Volume: 81, Issue:9, 1984
Potential protective effects of Clostridium butyricum on experimental gastric ulcers in mice.World journal of gastroenterology, , Jul-21, Volume: 21, Issue:27, 2015
[Clinical and experimental study on effect of Chinese herbal drugs on producing prostaglandin in gastric mucosa].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 14, Issue:9, 1994
Chronic gastritis, prostaglandins and Helicobacter pylori.Zeitschrift fur Gastroenterologie, , Volume: 31, Issue:10, 1993
Biosynthesis of TXB2 and 6-oxo-PGF1 alpha in the heart and other tissues under pathophysiological conditions.Agents and actions. Supplements, , Volume: 37, 1992
Theoretical mechanism for the gastrointestinal safety of etodolac: selective sparing of cytoprotective prostaglandins.Clinical rheumatology, , Volume: 8 Suppl 1, 1989
Prostanoid production in post-gastrectomy gastritis. Influence of sucralfate.The American journal of medicine, , Jun-09, Volume: 86, Issue:6A, 1989
[Tissue levels of 6-ketoprostaglandin Fl alpha and integrity of gastric mucosa in patients with Chagas disease].Arquivos de gastroenterologia, , Volume: 28, Issue:4
Effect of misoprostol on the course of viral hepatitis B.Hepato-gastroenterology, , Volume: 44, Issue:17
Prostaglandin and leukotriene concentration of the peritoneal fluid of endometriosis and other gynecologic disorders in the secretory phase.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Peritoneal fluid eicosanoids in chronic pelvic pain.Prostaglandins, , Volume: 38, Issue:4, 1989
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Prostacyclin and hormone levels in patients with symptoms of miscarriage and infection.Medicinski pregled, , Volume: 55, Issue:9-10
C-reactive protein and 6-keto prostaglandin F 1-alpha in patients with gynecologic cancer.Gynecologic oncology, , Volume: 36, Issue:2, 1990
Urinary 6-keto-prostaglandin F1a in patients with gynaecological tumours.Cancer letters, , Volume: 34, Issue:2, 1987
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Peripheral plasma immunoreactive 6-oxo-prostaglandin F1 alpha and gynaecological tumours.British journal of cancer, , Volume: 45, Issue:3, 1982
Glioma prostaglandin levels correlate with brain edema.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 18, Issue:2, 1998
Production of prostaglandins and thromboxane by isolated cells from intracranial tumours.Journal of neurology, neurosurgery, and psychiatry, , Volume: 47, Issue:6, 1984
Different effect of cyclosporine A and mycophenolate mofetil on passive Heymann nephritis in the rat.Nephron. Experimental nephrology, , Volume: 100, Issue:2, 2005
Inhibitory effects of ligustrazine, a modulator of thromboxane-prostacycline-nitric oxide balance, on renal injury in rats with passive Heyman nephritis.Nephron. Physiology, , Volume: 98, Issue:3, 2004
Effect of DP-1904, a thromboxane A2 synthase inhibitor, on passive Heymann nephritis in rats.European journal of pharmacology, , Nov-28, Volume: 316, Issue:1, 1996
Interleukin 4 downregulates cell growth and prostaglandin release of human mesangial cells.Biochemical and biophysical research communications, , Dec-15, Volume: 197, Issue:2, 1993
[Clinical and experimental study on effects of ji shen mixture for infantile acute glomerulonephritis].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:12, 1993
[Changes in renal cortical thromboxane A2, prostaglandin F1 alpha and effects of dazoxiben, chuan xiong on in situ immune complex glomerulonephritis in rats].Zhonghua yi xue za zhi, , Volume: 73, Issue:9, 1993
Synthesis and biological evaluation of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4-benzoquinone (CV-6504), a dual inhibitor of TXA2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species (AOS).Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21A, 1991
[The effect of decreased thromboxane synthesis on proliferative glomerulonephritis].Casopis lekaru ceskych, , Oct-18, Volume: 130, Issue:16-17, 1991
Effects of thromboxane synthetase inhibition on immune complex glomerulonephritis.American journal of veterinary research, , Volume: 52, Issue:3, 1991
Clinical effects of selective thromboxane A2 synthetase inhibitor in patients with nephrotic syndrome.Clinical nephrology, , Volume: 30, Issue:5, 1988
Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor.Prostaglandins, leukotrienes, and medicine, , Volume: 27, Issue:2-3, 1987
Glomerular and hormonal responses to dietary protein intake in human renal disease.The American journal of physiology, , Volume: 253, Issue:6 Pt 2, 1987
[Measurement of urinary TXB2, 6-keto-PGF1 alpha by radioimmunoassay and its clinical significance].Zhonghua nei ke za zhi, , Volume: 26, Issue:12, 1987
Effect of a thromboxane synthetase inhibitor on eicosanoid synthesis and glomerular injury during acute unilateral glomerulonephritis in the rat.Clinical nephrology, , Volume: 26, Issue:4, 1986
Indomethacin blunts the orthostatic increase in plasma aldosterone in glomerulonephritis.The Journal of clinical endocrinology and metabolism, , Volume: 59, Issue:2, 1984
Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin.The New England journal of medicine, , Feb-02, Volume: 310, Issue:5, 1984
Urinary excretion of prostaglandin F2 alpha and 6-keto-prostaglandin F1 alpha during volume expansion in patients with glomerulonephritis.Acta medica Scandinavica, , Volume: 212, Issue:5, 1982
Prostacyclin and thromboxane in chronic uremia: effect of hemodialysis.Clinical nephrology, , Volume: 18, Issue:2, 1982
Arachidonic acid, an in vivo inhibitor of carrageenin induced granulomas in the rat.European journal of pharmacology, , Apr-16, Volume: 110, Issue:3, 1985
Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide.Prostaglandins and medicine, , Volume: 5, Issue:4, 1980
Quantitative determination of 6-keto prostaglandin F1 alpha in biological fluids by capillary gas chromatography-chemical ionization mass spectrometry.Journal of chromatography, , Dec-12, Volume: 221, Issue:2, 1980
Prostaglandins E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 levels in carrageenin-induced inflammatory exudates in the rat air-pouch granuloma.Prostaglandins and medicine, , Volume: 2, Issue:4, 1979
Inhibition of tumor metastasis by carrageenan-induced granulomas.Clinical & experimental metastasis, , Volume: 7, Issue:1
Circulating prostacyclin and thromboxane in patients with Graves' disease.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:1, 1987
Differences in prostaglandin E2, prostaglandin F2 alpha and prostacyclin contents and their response to thyrotrophin stimulation and in prostaglandin-stimulated cyclic AMP response in normal and Grave's thyroid slices.The Journal of endocrinology, , Volume: 98, Issue:3, 1983
Head injury induces increased prostaglandin synthesis in rat brain.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 7, Issue:1, 1987
Thromboxane and prostacyclin in clinical acute respiratory failure.The Journal of surgical research, , Volume: 39, Issue:1, 1985
GC/MS analysis of prostaglandins in ventricular cerebrospinal fluid from head injured humans.Prostaglandins and medicine, , Volume: 7, Issue:2, 1981
Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin.American journal of medical genetics. Part A, , Volume: 152A, Issue:8, 2010
Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease.Circulation, , Volume: 88, Issue:5 Pt 1, 1993
Abnormalities in the biosynthesis of thromboxane A2 and prostacyclin in children with cyanotic congenital heart disease.British heart journal, , Volume: 69, Issue:2, 1993
Endogenous dilator prostaglandins in congenital heart disease.Pediatric cardiology, , Volume: 8, Issue:3, 1987
[Thromboxane-prostacyclin balance and platelet aggregability in patients with minor cardiac abnormalities].Terapevticheskii arkhiv, , Volume: 82, Issue:9, 2010
Selective thromboxane A2 synthase inhibition by OKY-046 prevents cardiopulmonary dysfunction after ovine smoke inhalation injury.Anesthesiology, , Volume: 102, Issue:5, 2005
Experimental study on microthrombi and myocardial injuries.Microvascular research, , Volume: 51, Issue:1, 1996
CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs.The American journal of physiology, , Volume: 264, Issue:4 Pt 2, 1993
Biosynthesis of TXB2 and 6-oxo-PGF1 alpha in the heart and other tissues under pathophysiological conditions.Agents and actions. Supplements, , Volume: 37, 1992
Free radicals in myocardial injury: experimental and clinical studies.Molecular and cellular biochemistry, , Volume: 111, Issue:1-2, 1992
[Changes in plasma TXB2 and 6-keto-PGF1 alpha and left atrial thrombosis in mitral stenosis].Zhonghua xin xue guan bing za zhi, , Volume: 18, Issue:2, 1990
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.Annals of surgery, , Volume: 212, Issue:6, 1990
[Plasma levels of prostaglandins and leukotrienes in vascular diseases].La Ricerca in clinica e in laboratorio, , Volume: 19 Suppl 1, 1989
[Clinical study of prostaglandin (PG) metabolism during extracorporeal circulation].[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, , Volume: 36, Issue:12, 1988
[Comparison of centrifugal pump (bio pump) with roller pump: clinical study].Kyobu geka. The Japanese journal of thoracic surgery, , Volume: 37, Issue:13, 1984
NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.Basic research in cardiology, , Volume: 103, Issue:5, 2008
Loop diuretics enhance the secretion of prostacyclin in vitro, in healthy persons, and in patients with chronic heart failure.European journal of clinical pharmacology, , Volume: 55, Issue:2, 1999
Hemodynamic and neurohumoral responses to exercise in patients with congestive heart failure.Japanese circulation journal, , Volume: 57, Issue:5, 1993
Effects of sustained ligustrazine on hemorrheology in patients with chronic pulmonary heart disease.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:3, 1992
[Pharmacological correction by roxicam of the prostacyclin-thromboxane system in acute myocardial infarction complicated by heart failure].Kardiologiia, , Volume: 31, Issue:8, 1991
[Piretanide in chronic and acute decompensated heart failure. Effect on hemodynamics and vasoactive hormones].Medizinische Klinik (Munich, Germany : 1983), , Jun-15, Volume: 84, Issue:6, 1989
Effects of rhein on renal arachidonic acid metabolism and renal function in patients with congestive heart failure.European journal of clinical pharmacology, , Volume: 37, Issue:1, 1989
Peripheral hemodynamic effects of captopril in patients with congestive heart failure.American heart journal, , Volume: 117, Issue:1, 1989
A double blind comparison of naproxen and sulindac in female patients with heart failure.Scandinavian journal of rheumatology. Supplement, , Volume: 62, 1986
Cardiovascular prostaglandins: some comments on their involvement in circulatory physiology and pathophysiology.Acta medica Scandinavica. Supplementum, , Volume: 707, 1986
Increased myocardial release of prostacyclin in dogs with heart failure.Journal of cardiovascular pharmacology, , Volume: 5, Issue:2
Hemodynamic changes and renal plasma flow in early heart failure: implications for renin, aldosterone, norepinephrine, atrial natriuretic peptide and prostacyclin.Basic research in cardiology, , Volume: 82, Issue:2
Oral nimodipine reduces prostaglandin and thromboxane production by arteries chronically exposed to a periarterial haematoma and the antifibrinolytic agent tranexamic acid.Journal of neurology, neurosurgery, and psychiatry, , Volume: 50, Issue:6, 1987
Arterial eicosanoid production following chronic exposure to a periarterial haematoma.Journal of neurology, neurosurgery, and psychiatry, , Volume: 47, Issue:7, 1984
Renal prostacyclin biosynthesis in a baboon model of Shiga toxin mediated hemolytic uremic syndrome.Nephron, , Volume: 92, Issue:2, 2002
Prostacyclin in diarrhoea-associated haemolytic uraemic syndrome.Pediatric nephrology (Berlin, Germany), , Volume: 7, Issue:5, 1993
Prostacyclin concentrations in haemolytic uraemic syndrome after acute shigellosis in children.Archives of disease in childhood, , Volume: 66, Issue:10, 1991
Absence of plasma prostacyclin stimulating activity deficiency in hemolytic uremic syndrome.The Journal of pediatrics, , Volume: 111, Issue:1, 1987
In vitro prostacyclin production in the hemolytic-uremic syndrome.The Western journal of medicine, , Volume: 144, Issue:2, 1986
6-keto-PGF1 alpha levels and prostacyclin therapy in 2 adult patients with hemolytic-uremic syndrome.Clinical nephrology, , Volume: 26, Issue:3, 1986
Prostanoids in hemolytic uremic syndrome.The Journal of pediatrics, , Volume: 106, Issue:6, 1985
Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure.Thrombosis research, , Apr-01, Volume: 30, Issue:1, 1983
Prostacyclin and haemolytic, thrombocytopenic microangiopathy.Lancet (London, England), , Sep-05, Volume: 2, Issue:8245, 1981
Ent-16β,17-dihydroxy-kauran-19-oic acid, a kaurane diterpene acid from Siegesbeckia pubescens, presents antiplatelet and antithrombotic effects in rats.Phytomedicine : international journal of phytotherapy and phytopharmacology, , Jul-15, Volume: 18, Issue:10, 2011
Early inflammatory response correlates with the severity of injury.Critical care medicine, , Volume: 24, Issue:7, 1996
Exaggerated splanchnic PGI2 release following acute hemorrhage is due to new protein synthesis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 48, Issue:3, 1993
Cyclooxygenase and lipoxygenase metabolism in sodium taurocholate induced acute hemorrhagic pancreatitis in rats.Prostaglandins, , Volume: 45, Issue:4, 1993
[Plasma PGI2 and TXA2 levels on a model of PDH in leptospirosis].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 22, Issue:3, 1991
Ridogrel in the setting of percutaneous transluminal coronary angioplasty.The American journal of cardiology, , Aug-15, Volume: 68, Issue:5, 1991
Combination therapy with low-dose aspirin and ticlopidine in cerebral ischemia.Stroke, , Volume: 20, Issue:12, 1989
Is there a role for leukotrienes as mediators of ethanol-induced gastric mucosal damage?The American journal of physiology, , Volume: 254, Issue:1 Pt 1, 1988
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs.The Journal of surgical research, , Volume: 42, Issue:3, 1987
Blood conservation with membrane oxygenators and dipyridamole.The Annals of thoracic surgery, , Volume: 44, Issue:1, 1987
Renal hemodynamic effects of therapeutic plasma levels of sulindac sulfide during hemorrhage.Kidney international, , Volume: 29, Issue:2, 1986
Maintenance of cerebral circulation during hemorrhagic hypotension in newborn pigs: role of prostanoids.Circulation research, , Volume: 59, Issue:5, 1986
Effect of prostaglandin blockers on ascites fluid in pancreatitis.Surgery, , Volume: 98, Issue:3, 1985
Accumulation of prostacyclin in rat brain during haemorrhagic hypotension--possible role of PGI2 in autoregulation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 4, Issue:1, 1984
Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat. Differentiation of effects between nabumetone and etodolac.Digestive diseases and sciences, , Volume: 39, Issue:3, 1994
Comparison of the effects of nabumetone with indomethacin on rat gastric mucosal 6-keto-PGF1 alpha production and on bile salt-induced changes in gastric mucosal function.The Journal of pharmacy and pharmacology, , Volume: 39, Issue:9, 1987
Gastroprotection by sucralfate against acetylsalicylic acid in humans. Role of endogenous prostaglandins.Scandinavian journal of gastroenterology. Supplement, , Volume: 140, 1987
Gastroprotective effects of morniflumate, an esterified anti-inflammatory drug.Arzneimittel-Forschung, , Volume: 34, Issue:8, 1984
[Effect of moxibustion on humoral factors in the rat infected with epidemic hemorrhagic fever virus].Zhen ci yan jiu = Acupuncture research, , Volume: 17, Issue:4, 1992
[Influence of moxibustion on TXA2 and PGI2 in plasma of rat infected epidemic hemorrhagic fever virus (EHFV)].Zhen ci yan jiu = Acupuncture research, , Volume: 17, Issue:1, 1992
[A study of the role of plasma thromboxane B2 and 6-keto-prostaglandin F1 alpha in epidemic hemorrhagic fever].Zhonghua nei ke za zhi, , Volume: 29, Issue:3, 1990
[Role of thromboxane A2 and prostacyclin in the pathophysiology of epidemic hemorrhagic fever].Zhonghua yi xue za zhi, , Volume: 70, Issue:7, 1990
Plasma iPGE2 and i6-keto PGF1 alpha in the course of liver cirrhosis.Prostaglandins, , Volume: 53, Issue:1, 1997
[Relation of changes in plasma TXB2 PGF1alpha and differentiation of signs and symptoms in traditional Chinese medicine in severe icteric hepatitis].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:3, 1990
Effect of misoprostol on the course of viral hepatitis B.Hepato-gastroenterology, , Volume: 44, Issue:17
NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines.International journal of cancer, , Jun-10, Volume: 99, Issue:5, 2002
Some features in prostaglandin synthesis of the cancer cells which metastasized into liver from intestinal cancer lesions.The Tohoku journal of experimental medicine, , Volume: 170, Issue:2, 1993
Comparison of prostanoids and their precursor fatty acids in human hepatocellular carcinoma and noncancerous reference tissues.The Journal of surgical research, , Volume: 54, Issue:1, 1993
Urinary excretion of prostaglandins and renal function after hepatic resection.Hepato-gastroenterology, , Volume: 44, Issue:15
Extra- and intracellular potassium concentration and prostaglandin production of skin fibroblasts grown from patients with Bartter's syndrome.Prostaglandins, leukotrienes, and medicine, , Volume: 21, Issue:1, 1986
Prostaglandin excretion in Bartter's syndrome.Klinische Wochenschrift, , Jan-03, Volume: 61, Issue:1, 1983
Systemic prostaglandin I2 synthesis is normal in patients with Bartter's syndrome.Lancet (London, England), , Aug-13, Volume: 2, Issue:8346, 1983
Comparison of prostaglandin production of skin fibroblasts grown from patients with Bartter's syndrome and from age and sex matched controls.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
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The principal metabolites of arachidonic acid are overproduced in Bartter's syndrome.Advances in prostaglandin and thromboxane research, , Volume: 7, 1980
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[Some mechanisms of the development of endothelial disfunction in aging].Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), , Volume: 50, Issue:2, 2004
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Relationship between opioids and prostaglandins in hypoxia-induced vasodilation of pial arteries in the newborn pig.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 212, Issue:2, 1996
Role of prostaglandins and histamine in hyperemic response to superficial and deep gastric mucosal injury and H+ back-diffusion in cats.Digestive diseases and sciences, , Volume: 40, Issue:8, 1995
Mechanism of aggravation of mucosal injury by intravenous nicotine in rat stomach.The American journal of physiology, , Volume: 261, Issue:6 Pt 1, 1991
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Interaction of nicotine and prostaglandins in the cardiovascular system.Prostaglandins, , Volume: 23, Issue:1, 1982
Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man.Prostaglandins, leukotrienes, and medicine, , Volume: 9, Issue:4, 1982
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Myocardial reactive hyperaemia in perfused guinea pig heart.Polish journal of pharmacology, , Volume: 47, Issue:5
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Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:5, 2000
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Effects of medicinal cake-separated moxibustion on plasma 6-keto-PGF1alpha and TXB2 contents in the rabbit of hyperlipemia.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 25, Issue:2, 2005
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Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia?Journal of hypertension, , Volume: 17, Issue:9, 1999
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Influences of dietary omega-3 polyunsaturated fatty acids on the recovery of cardiac and renal functions after preservation in hyperlipidemic rats.Transplantation, , Aug-15, Volume: 64, Issue:3, 1997
[Effects of acupuncture on lipid, TXB2, 6-keto-PGF, alpha in simple obese patients complicated with hyperlipidemia].Zhen ci yan jiu = Acupuncture research, , Volume: 21, Issue:4, 1996
Influence of HDL on the formation of 6-keto-PGF1 alpha and TXB2 in vitro: the importance of the source of HDL.Eicosanoids, , Volume: 5, Issue:1, 1992
[Effect of jiang-zhi zhong-yao-pian on total cholesterol, triglyceride, TXB2, 6-keto-PGF1 alpha in hyperlipemic patients].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:1, 1991
[Effects of nifedipine and Paeonia lactiflora on plasma TXB2 and 6-Keto-PGF1 alpha in cholesterol-fed rabbits].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:11, 1990
Effects of purified compound (8501) on hyperlipidemia and the balance between thromboxane A2 and prostacyclin in rabbits.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 5, Issue:4, 1990
[Effects of corn pollen on the peroxides and 6-keto-PGF1 alpha/TXB2 in hyperlipidemic rabbits].Zhonghua xin xue guan bing za zhi, , Volume: 18, Issue:6, 1990
[Plasma and cellular factors of atherogenesis and the prostanoid system at the early stages of arterial hypertension].Kardiologiia, , Volume: 29, Issue:9, 1989
[Effect of the leech on 6-keto-PGF1 alpha, TXB2, total cholesterol and triglycerides in experimental hyperlipemic rabbits].Zhonghua nei ke za zhi, , Volume: 27, Issue:8, 1988
Increased compliance of niceritrol treatment by addition of aspirin: relationship between changes in prostaglandins and skin flushing.International journal of clinical pharmacology, therapy, and toxicology, , Volume: 25, Issue:12, 1987
[Effect of pollen typhae on 6-keto-PGF1 alpha, TXB2, TC and HDL-C in chronic hyperlipemic rabbits].Zhonghua xin xue guan bing za zhi, , Volume: 14, Issue:5, 1986
Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts.Journal of cardiovascular pharmacology, , Volume: 36, Issue:5, 2000
Eicosapentanoic acid suppresses intimal hyperplasia after expanded polytetrafluoroethylene grafting in rabbits fed a high cholesterol diet.Journal of vascular surgery, , Volume: 13, Issue:4, 1991
Correlation between the effects of aspirin and dipyridamole on platelet function and prevention of intimal hyperplasia in autologous vein grafts.The Canadian journal of cardiology, , Volume: 4, Issue:1
Potential Biomarkers for the Diagnosis of Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema.ORL; journal for oto-rhino-laryngology and its related specialties, , Volume: 79, Issue:1-2, 2017
Pro Atrial Natriuretic Peptide (1-30) and 6-keto PGF1α Activity Affects Na(+) Homeostasis in Non-modulating Hypertension.Current hypertension reviews, , Volume: 11, Issue:1, 2015
Vasoconstrictor role of cyclooxygenase-1-mediated prostacyclin synthesis in non-insulin-dependent diabetic mice induced by high-fat diet and streptozotocin.American journal of physiology. Heart and circulatory physiology, , Aug-01, Volume: 307, Issue:3, 2014
Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.The Journal of clinical investigation, , Volume: 122, Issue:4, 2012
[Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 10, Issue:9, 2012
Suppression of the nitric oxide pathway in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-signaling inhibitors.Hypertension (Dallas, Tex. : 1979), , Volume: 56, Issue:6, 2010
Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats.Clinical and experimental hypertension (New York, N.Y. : 1993), , Volume: 32, Issue:7, 2010
Diagnostic biomarkers of essential arterial hypertension: the value of prostacyclin, nitric oxide, oxidized-LDL, and peroxide measurements.International heart journal, , Volume: 50, Issue:3, 2009
Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up.Journal of the neurological sciences, , Dec-15, Volume: 287, Issue:1-2, 2009
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.Journal of hypertension, , Volume: 26, Issue:12, 2008
Changes of TXA2 and PGI2 during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, , Volume: 28, Issue:1, 2008
Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage.Chinese medical journal, , Dec-05, Volume: 120, Issue:23, 2007
Oral treatment and in vitro incubation with fructose modify vascular prostanoid production in the rat.Autonomic & autacoid pharmacology, , Volume: 26, Issue:1, 2006
Angiotensin II type 1 receptor antagonism improves endothelial vasodilator function in L-NAME-induced hypertensive rats by a kinin-dependent mechanism.Journal of hypertension, , Volume: 24, Issue:1, 2006
Angiotensin-converting enzyme inhibition and angiotensin AT1-receptor antagonism equally improve endothelial vasodilator function in L-NAME-induced hypertensive rats.European journal of pharmacology, , Jun-15, Volume: 516, Issue:3, 2005
[Insulin resistance and effects of intravenous acute saline load on renal production of prostaglandin I2 and thromboxane A2 in salt-sensitive hypertensive patients].Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, , Volume: 25, Issue:1, 2005
Decreased nitric oxide in women with essential hypertension in prehypertensive phase.Croatian medical journal, , Volume: 46, Issue:6, 2005
Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats.Canadian journal of physiology and pharmacology, , Volume: 83, Issue:6, 2005
Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients.Life sciences, , Jan-02, Volume: 74, Issue:7, 2004
Functional study of the [Ca2+]i signaling pathway in aortas of L-NAME-hypertensive rats.Pharmacology, , Volume: 70, Issue:3, 2004
Prostaglandin I2 does not contribute to the hypotensive effect of the superoxide dismutase mimetic Tempo in rats with aortic coarctation-induced hypertension.Clinical and experimental hypertension (New York, N.Y. : 1993), , Volume: 26, Issue:3, 2004
Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients.Renal failure, , Volume: 25, Issue:4, 2003
Dietary fish protein lowers blood pressure and alters tissue polyunsaturated fatty acid composition in spontaneously hypertensive rats.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 19, Issue:4, 2003
1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats.Peptides, , Volume: 23, Issue:1, 2002
Enalapril and quinapril improve endothelial vasodilator function and aortic eNOS gene expression in L-NAME-treated rats.European journal of pharmacology, , Aug-16, Volume: 450, Issue:1, 2002
Serotonin hypersensitivity in aorta of two kidney-two clip hypertensive rats: calcium contribution and prostanoids-nitric oxide interactions.Archives of physiology and biochemistry, , Volume: 109, Issue:1, 2001
Gender differences in the attenuation of salt-induced hypertension by angiotensin (1-7).Peptides, , Volume: 22, Issue:6, 2001
Chronic thromboxane synthase inhibition prevents fructose-induced hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 38, Issue:4, 2001
[Clinical study on conducting physical exercise in lowering blood pressure of hypertensive patients and influencing their endocrine hormones].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 21, Issue:12, 2001
Prostacyclin deficiency and reduced fetoplacental blood flow in pregnancy-induced hypertension and preeclampsia.Gynecologic and obstetric investigation, , Volume: 50, Issue:2, 2000
Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 63, Issue:4, 2000
Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 27, Issue:8, 2000
Different patterns of renal prostaglandins I2 and E2 in patients with essential hypertension with low to normal or high renin activity.Journal of hypertension, , Volume: 18, Issue:8, 2000
Plasma levels of nitric oxide and related vasoactive factors following long-term treatment with angiotensin-converting enzyme inhibitor in patients with essential hypertension.Metabolism: clinical and experimental, , Volume: 48, Issue:10, 1999
Exercise enhances vasorelaxation in experimental obesity associated hypertension.Cardiovascular research, , Volume: 43, Issue:4, 1999
Prostacyclin: its pathogenic role in essential hypertension and the class effect of ACE inhibitors on prostaglandin metabolism.Blood pressure, , Volume: 8, Issue:5-6, 1999
Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia?Journal of hypertension, , Volume: 17, Issue:9, 1999
Effects of ridogrel, a thromboxane synthase inhibitor and receptor antagonist, on blood pressure in the spontaneously hypertensive rat.Japanese journal of pharmacology, , Volume: 78, Issue:4, 1998
Role of endogenous carbon monoxide in hypertension pathogenesis of rats.Sheng li xue bao : [Acta physiologica Sinica], , Volume: 50, Issue:6, 1998
Glomerular thromboxane contributes to pressor response in deoxycorticosterone acetate-salt hypertension.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 58, Issue:2, 1998
Production of eicosanoids and angiotensin II in resistance vessels in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 25, Issue:6, 1998
Compensatory excretion of prostacyclin and thromboxane metabolites in obstructive sleep apnea syndrome.Internal medicine (Tokyo, Japan), , Volume: 37, Issue:2, 1998
Stimulation of endothelial cell production of vasoconstrictive substances by hypertensive sera.American journal of hypertension, , Volume: 11, Issue:2, 1998
Vasoactive mediators in pregnancy-induced hypertensive disorders: a longitudinal study.American journal of obstetrics and gynecology, , Volume: 179, Issue:6 Pt 1, 1998
Effects of cicletanine on prostaglandin I2 and E2 levels in patients with essential hypertension.American journal of hypertension, , Volume: 10, Issue:7 Pt 1, 1997
[Influence of qi-gong on plasma TXB2 and 6-keto-PGF1 alpha in two TCM types of essential hypertension].Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, , Volume: 22, Issue:6, 1997
Thromboxane antagonism and cough induced by angiotensin-converting-enzyme inhibitor.Lancet (London, England), , Jul-05, Volume: 350, Issue:9070, 1997
Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study.American journal of obstetrics and gynecology, , Volume: 177, Issue:6, 1997
Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 80, Issue:1, 1996
[Study on mechanism of eye-signs in blood stasis syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:4, 1996
Vasoconstriction of the afferent arteriole and defective renal synthesis of nitric oxide in essential hypertension.Kidney international. Supplement, , Volume: 55, 1996
[Level of endothelin-1,2,6-keto-pgf1-alpha and atrial natriuretic peptide in serum of pregnant women with late hypertension].Polskie Archiwum Medycyny Wewnetrznej, , Volume: 95, Issue:6, 1996
Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin.The Journal of pharmacology and experimental therapeutics, , Volume: 279, Issue:2, 1996
Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 54, Issue:3, 1996
Prostacyclin biosynthesis in essential hypertension before and during treatment.Journal of human hypertension, , Volume: 10, Issue:1, 1996
Mesenteric vascular responses to vasopressin during development of DOCA-salt hypertension in male and female rats.The American journal of physiology, , Volume: 268, Issue:1 Pt 2, 1995
Determination of mineral, parathyroid hormone, and 6-keto-prostaglandin-F1 alpha levels in pregnant women with hypertension and pre-eclampsia.Singapore medical journal, , Volume: 36, Issue:6, 1995
[Effect of trapidil in prevention of pre-eclampsia and fetal retardation].Zentralblatt fur Gynakologie, , Volume: 117, Issue:1, 1995
Phorbol ester-stimulated 6-keto-prostaglandin F1 alpha in aortas from control and aldosterone-salt rats.Journal of hypertension, , Volume: 13, Issue:7, 1995
Adriamycin-related hypertension in pregnant rats: response to a thromboxane receptor antagonist.Clinical science (London, England : 1979), , Volume: 88, Issue:6, 1995
Short-term increase in prostaglandin I2 synthesis caused by cicletanine in patients with essential hypertension.American journal of hypertension, , Volume: 8, Issue:9, 1995
Hypertensive and normal pregnancy: a longitudinal study of blood pressure, distensibility of dorsal hand veins and the ratio of the stable metabolites of thromboxane A2 and prostacyclin in plasma.British journal of obstetrics and gynaecology, , Volume: 102, Issue:11, 1995
Amlodipine and haemodynamic effects of cyclo-oxygenase inhibition.British journal of clinical pharmacology, , Volume: 39, Issue:1, 1995
[Value of prostaglandins in a pre-eclampsia-equivalent animal model].Zentralblatt fur Gynakologie, , Volume: 116, Issue:5, 1994
The change of penile blood thromboxane B2 and prostacyclin after intracavernous injection of vasoactive drugs for the treatment of arteriogenic impotence.Proceedings of the National Science Council, Republic of China. Part B, Life sciences, , Volume: 18, Issue:1, 1994
[Vasoactive prostanoids and inhibitors of blood coagulation in pregnancy-induced hypertension].Zentralblatt fur Gynakologie, , Volume: 116, Issue:6, 1994
Ridogrel improves maternal/fetal homeostasis in an ovine model of pregnancy-induced hypertension.Prostaglandins, , Volume: 47, Issue:3, 1994
Effect of low-dose treatment with perindopril on cardiac function in stroke-prone spontaneously hypertensive rats: role of bradykinin.Journal of cardiovascular pharmacology, , Volume: 24, Issue:3, 1994
Effects of swim training on blood pressure, catecholamines and prostaglandins in spontaneously hypertensive rats.Japanese heart journal, , Volume: 35, Issue:2, 1994
Tacrolimus (FK506)-induced nephrotoxicity in spontaneous hypertensive rats.The Journal of toxicological sciences, , Volume: 19, Issue:4, 1994
Plasma and urinary endothelin 1, prostacyclin metabolites and platelet consumption in pre-eclampsia and essential hypertensive pregnancy.Blood pressure, , Volume: 3, Issue:1-2, 1994
Systemic and renal effects of nifedipine in cyclosporine-associated hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 23, Issue:1 Suppl, 1994
Hemodynamic and biochemical changes after chronic administration of cilazapril to hypertensive patients.Cardiology, , Volume: 82, Issue:4, 1993
Effect of felodipine-ER on blood pressure, platelet function, and rheological properties in hypertension.The Canadian journal of cardiology, , Volume: 9, Issue:5, 1993
Effects of naftidrofuryl on isolated perfused kidneys of spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 20, Issue:10, 1993
Prostacyclin, thromboxane and antioxidant levels in pregnancy-induced hypertension.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 50, Issue:3, 1993
Correlation between umbilical artery resistance index, 6 ketoprostaglandin F1 alpha and thromboxane B2 in the fetoplacental compartment in patients with pregnancy induced hypertension.Prostaglandins, , Volume: 45, Issue:6, 1993
[The influence of indapamide on 6-keto-PGF1 alpha, PGE2, and PGF2 alpha synthesis and plasma TXB2 levels in spontaneously hypertensive rats].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 15, Issue:1, 1993
The effect of acetaminophen on prostacyclin production in pregnant women.American journal of obstetrics and gynecology, , Volume: 168, Issue:4, 1993
Mechanism for the antihypertensive effect of a polysaccharide-glycopeptide complex from Lactobacillus casei in spontaneously hypertensive rats (SHR).Bioscience, biotechnology, and biochemistry, , Volume: 57, Issue:6, 1993
Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease.Kidney international, , Volume: 41, Issue:1, 1992
3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.Journal of medicinal chemistry, , Feb-21, Volume: 35, Issue:4, 1992
Protective effect of cicletanine on hypertension-induced decreases in the renal kallikrein-kinin and prostaglandin systems in stroke-prone spontaneously hypertensive rats.Journal of cardiovascular pharmacology, , Volume: 20, Issue:4, 1992
Abnormal response of urinary eicosanoid system to norepinephrine infusion in patients with essential hypertension.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 46, Issue:2, 1992
Effects of prostacyclin infusion on blood pressure and plasma renin activity in patients with essential hypertension.Angiology, , Volume: 43, Issue:2, 1992
Study of mechanisms of glucocorticoid hypertension in rats: endothelial related changes and their amelioration by dietary fish oils.British journal of pharmacology, , Volume: 106, Issue:2, 1992
[Clinical study of qianxining in the treatment of 60 cases of yang hyperactivity due to yin deficiency type of hypertension].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 12, Issue:7, 1992
[Effects of svate on platelet morphology and function in patients with coronary heart disease and hypertension].Zhonghua xin xue guan bing za zhi, , Volume: 19, Issue:3, 1991
Effect of angiotensin-converting enzyme inhibitors on glomerular eicosanoid production in normotensive and spontaneously hypertensive rats.Clinical science (London, England : 1979), , Volume: 81, Issue:4, 1991
Urinary excretion of prostanoids during sleep in obstructive sleep apnoea patients.Clinical and experimental pharmacology & physiology, , Volume: 18, Issue:8, 1991
Nifedipine increases urinary excretion of prostacyclin metabolite in hypertensive pregnancy.Pharmacology & toxicology, , Volume: 69, Issue:1, 1991
Vascular eicosanoids and platelet-aortic wall interactions in spontaneously hypertensive rats.European journal of pharmacology, , Sep-24, Volume: 202, Issue:3, 1991
[Experimental study on the treatment of hypertension with combined traditional Chinese and Western medicine].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:11, 1991
Role of prostanoids in renin-dependent and renin-independent hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 17, Issue:4, 1991
Arachidonic acid does not share the antihypertensive properties of linoleic acid and fish oil omega-3 fatty acids in a model of angiotensin II-induced hypertension in the rat.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 14, Issue:6, 1991
Renal eicosanoids and renal hemodynamics in early borderline hypertension.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 14, Issue:6, 1991
Endothelins in perinatal biology.Seminars in perinatology, , Volume: 15, Issue:1, 1991
Absence of effects of ketanserin on renal prostacyclin and thromboxane A2 in essential hypertension.European heart journal, , Volume: 12, Issue:4, 1991
Effect of aging on endothelin-induced prostaglandin I2 release in isolated hind legs of the spontaneously hypertensive rat.Research communications in chemical pathology and pharmacology, , Volume: 74, Issue:2, 1991
[Effect of captopril on urinary 6-keto-PGF1 alpha, thromboxane B2 in inbred SHR rats].Zhonghua xin xue guan bing za zhi, , Volume: 19, Issue:6, 1991
Effects of isradipine on platelet function in hypertension at rest and during exercise.American journal of hypertension, , Volume: 4, Issue:2 Pt 2, 1991
The deficit of prostacyclin in the pathogenesis of hypertension.Cor et vasa, , Volume: 33, Issue:6, 1991
Effect of dietary calcium on renal prostaglandins.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 42, Issue:3, 1991
Low-dose aspirin. II. Relationship of angiotensin II pressor responses, circulating eicosanoids, and pregnancy outcome.American journal of obstetrics and gynecology, , Volume: 163, Issue:6 Pt 1, 1990
Antithrombotic activity of garlic: its inhibition of the synthesis of thromboxane-B2 during infusion of arachidonic acid and collagen in rabbits.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 41, Issue:2, 1990
[The effect of eicosapentaenoic acid enriched marine oil on the platelet function in hypercoagulable state].Zhonghua nei ke za zhi, , Volume: 29, Issue:7, 1990
Design of an antithrombotic-antihypertensive agent (Wy 27569). Synthesis and evaluation of a series of 2-heteroaryl-substituted dihydropyridines.Journal of medicinal chemistry, , Volume: 33, Issue:2, 1990
Prostanoids and aldosterone-induced mild experimental hypertension in rats.Hypertension (Dallas, Tex. : 1979), , Volume: 15, Issue:2, 1990
[Prostacyclin and metabolite assay and the clinical significance].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 48 Suppl, 1990
Effects of bopindolol on platelet function in hypertension at rest and during exercise.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 40, Issue:2, 1990
Platelet activity, prostacycline metabolite, plasma lipids and sympathoadrenal activity in patients with borderline hypertension and a positive family history of hypertension.Cor et vasa, , Volume: 32, Issue:4, 1990
Changes in vascular wall production of prostacyclin and thromboxane A2 in spontaneously hypertensive rats during maturation and the concomitant development of hypertension.Japanese circulation journal, , Volume: 54, Issue:5, 1990
Effect of furosemide on angiotensin II-mediated prostaglandin I2 production in hypertensive subjects.European journal of clinical pharmacology, , Volume: 39, Issue:2, 1990
An increase in the ratio of thromboxane A2 to prostacyclin in association with increased blood pressure in patients on cyclosporine A.Prostaglandins, , Volume: 37, Issue:5, 1989
The influence of dietary protein on the synthesis of vasoactive substances in subtotally nephrectomized spontaneously hypertensive rats.Japanese heart journal, , Volume: 30, Issue:6, 1989
Effect of sodium intake on the hypotensive effect of calcium antagonists.Japanese heart journal, , Volume: 30, Issue:6, 1989
[Plasma and cellular factors of atherogenesis and the prostanoid system at the early stages of arterial hypertension].Kardiologiia, , Volume: 29, Issue:9, 1989
Increased prostaglandin synthesis in the unclipped kidney of one-kidney, one clip hypertensive rats.Journal of hypertension, , Volume: 7, Issue:11, 1989
Hypertension in bone marrow transplanted patients.Acta clinica Belgica, , Volume: 44, Issue:5, 1989
Role of prostaglandin I2 and thromboxane A2 in the regulation of blood pressure.Nihon Jinzo Gakkai shi, , Volume: 31, Issue:6, 1989
Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.The New England journal of medicine, , Aug-10, Volume: 321, Issue:6, 1989
Hostile personality characteristics and prostaglandins in essential hypertension.Psychotherapy and psychosomatics, , Volume: 52, Issue:4, 1989
Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins.Hypertension (Dallas, Tex. : 1979), , Volume: 14, Issue:4, 1989
Effect of sodium restriction on platelet function in patients with essential hypertension.Japanese heart journal, , Volume: 30, Issue:3, 1989
Prostacyclin synthesis is increased during propranolol therapy for essential hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 19, 1989
Effect of pure eicosapentaenoic acid feeding on blood pressure and vascular reactivity in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 15, Issue:4, 1988
[Basic and clinical studies of angiotensin II pressor responsiveness in pregnancy-induced-hypertension].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 40, Issue:8, 1988
Urinary excretion of 6-keto prostaglandin F1 alpha in pre-eclampsia.Archives of gynecology and obstetrics, , Volume: 244, Issue:1, 1988
Prostanoid response in the kidney of hypertensive subjects as part of renal counteraction to gallopamil-induced blood pressure decrease.Acta medica Hungarica, , Volume: 45, Issue:3-4, 1988
Prostacyclin and thromboxane in pregnancy-induced hypertension.Chinese medical journal, , Volume: 101, Issue:12, 1988
Thromboxane A2 and the development of hypertension in spontaneously hypertensive rats.European journal of pharmacology, , Jan-27, Volume: 146, Issue:1, 1988
Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema.Stroke, , Volume: 19, Issue:3, 1988
Effects of DOCA-salt treatment on the urinary prostaglandins in Sabra rats.Kidney international, , Volume: 33, Issue:5, 1988
Effect of potassium supplementation on blood pressure and vasodilator mechanisms in spontaneously hypertensive rats.Clinical science (London, England : 1979), , Volume: 75, Issue:5, 1988
Altered excretion of prostaglandin and thromboxane metabolites in pregnancy-induced hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 11, Issue:6 Pt 1, 1988
The effect of dietary fish oil and long-term salt loading on blood pressure and eicosanoid metabolism in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 15, Issue:4, 1988
Prostacyclin in (extracted) plasma of essential hypertensives.Acta cardiologica, , Volume: 42, Issue:2, 1987
Antihypertensive activity of enalapril. Effect of ibuprofen and different salt intakes.Journal of clinical hypertension, , Volume: 3, Issue:4, 1987
Dietary suppression of prostaglandin synthesis does not accelerate DOCA/salt hypertension in rats.Clinical and experimental pharmacology & physiology, , Volume: 14, Issue:6, 1987
Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin.The American journal of the medical sciences, , Volume: 294, Issue:6, 1987
Effects of indomethacin on hormonal and blood pressure responses to captopril in spontaneously hypertensive rats.Pharmacology & toxicology, , Volume: 61, Issue:3, 1987
Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension.Circulation, , Volume: 75, Issue:5, 1987
Potassium supplementation lowers blood pressure in spontaneously hypertensive rats--relationships with urinary prostaglandins and renin.Agents and actions. Supplements, , Volume: 22, 1987
[Preliminary study on plasma 6-keto-prostaglandin F1 alpha levels before and after induction by furosemide in hypertensive patients].Zhonghua xin xue guan bing za zhi, , Volume: 15, Issue:3, 1987
Indomethacin reduces the antihypertensive action of enalapril.Clinical and experimental hypertension. Part A, Theory and practice, , Volume: 9, Issue:2-3, 1987
Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension.American journal of perinatology, , Volume: 4, Issue:2, 1987
Beneficial effects of U-63,557A, a thromboxane synthetase inhibitor, in an ovine model of pregnancy-induced hypertension.American journal of obstetrics and gynecology, , Volume: 157, Issue:1, 1987
[Effect of erect posture on prostacyclin and catecholamines in patients with arterial hypertension].Kardiologia polska, , Volume: 30, Issue:9, 1987
[Measurement of urinary TXB2, 6-keto-PGF1 alpha by radioimmunoassay and its clinical significance].Zhonghua nei ke za zhi, , Volume: 26, Issue:12, 1987
[Blood lipids, catecholamines, beta-thromboglobulin and prostacyclin in primary arterial hypertension].Kardiologia polska, , Volume: 30, Issue:9, 1987
Different excretion pattern of urinary PGE2 and 6-keto-PGF1 alpha in two kidney-one clip Goldblatt rats.Prostaglandins, leukotrienes, and medicine, , Volume: 24, Issue:1, 1986
Effect of non-steroidal anti-inflammatory drugs on control of hypertension by beta-blockers and diuretics.Lancet (London, England), , May-03, Volume: 1, Issue:8488, 1986
The arthritic patient with hypertension: selection of an NSAID.Scandinavian journal of rheumatology. Supplement, , Volume: 62, 1986
Altered angiotensin-prostanoid interactions in umbilical arteries in pregnancy-induced hypertension.Scandinavian journal of clinical and laboratory investigation. Supplementum, , Volume: 184, 1986
Production of prostaglandins I2, E2 and F2 alpha by blood vessels of normotensive and hypertensive, male and female rats.Prostaglandins, leukotrienes, and medicine, , Volume: 25, Issue:2-3, 1986
[Plasma thromboxane B2 and 6-keto-prostaglandin F1-alpha concentrations in patients with essential and renovascular hypertension].Zhonghua xin xue guan bing za zhi, , Volume: 14, Issue:1, 1986
Combination therapy with enalapril and hydrochlorothiazide: optimal dose, renin response, and prostaglandin excretion.Journal of clinical hypertension, , Volume: 2, Issue:1, 1986
Effects of kallidinogenase on urinary kallikrein excretion and plasma prostanoid concentrations in patients with essential hypertension.Experientia, , Sep-15, Volume: 42, Issue:9, 1986
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.Arzneimittel-Forschung, , Volume: 36, Issue:1, 1986
The antihypertensive action of hydrochlorothiazide and renal prostacyclin.Clinical pharmacology and therapeutics, , Volume: 39, Issue:1, 1986
[Effect of bilateral common carotid artery ligation on prostaglandin levels (TXA2, PGI2) in spontaneously hypertensive rats (SHRSP, SHRSR) and normotensive rats (WKY)].No to shinkei = Brain and nerve, , Volume: 38, Issue:6, 1986
[Hypertension research in China].Zhonghua xin xue guan bing za zhi, , Volume: 14, Issue:1, 1986
Arachidonic acid-induced brain ischaemia: different severity between stroke-resistant spontaneously hypertensive rats and Wistar-Kyoto rats.Journal of hypertension. Supplement : official journal of the International Society of Hypertension, , Volume: 4, Issue:3, 1986
Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans.Prostaglandins, leukotrienes, and medicine, , Volume: 23, Issue:2-3, 1986
The effects of nifedipine on platelet aggregation and plasma 6-keto-PGF1 alpha, and its interaction with indomethacin.European journal of clinical pharmacology, , Volume: 29, Issue:4, 1985
[Effect of saralasin on the activity of the renin-angiotensin-aldosterone system, sympathetic-adrenal system and the level of the 6-keto-PGF1 alpha metabolite of prostacyclin in patients with primary arterial hypertension].Kardiologia polska, , Volume: 28, Issue:7, 1985
Prostaglandins, renin-angiotensin system, and hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Dietary fish oil prevents dexamethasone induced hypertension in the rat.Clinical science (London, England : 1979), , Volume: 69, Issue:6, 1985
Prostacyclin in normal and hypertensive pregnancy.American journal of obstetrics and gynecology, , Nov-15, Volume: 153, Issue:6, 1985
Inhibition of prostaglandin synthesis by indomethacin interacts with the antihypertensive effect of atenolol.Clinical pharmacology and therapeutics, , Volume: 38, Issue:4, 1985
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Urinary levels of 2,3-dinor-6-oxo-PGF1 alpha: a reliable index of the production of PGI2 in the spontaneously hypertensive rat.Prostaglandins, , Volume: 29, Issue:4, 1985
Effects of orally administered glandular kallikrein on urinary kallikrein and prostaglandin excretion, plasma immunoreactive prostanoids and platelet aggregation in essential hypertension.Klinische Wochenschrift, , Apr-01, Volume: 63, Issue:7, 1985
Renal prostaglandins and hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Urinary 6-keto-PGF1 alpha after captopril and indomethacin: possible contribution of PGI2 to the antihypertensive mechanism of ACE inhibitors.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids.Obstetrics and gynecology, , Volume: 65, Issue:1, 1985
Plasma concentrations of 6-keto-prostaglandin F1 alpha, thromboxane B2 and platelet aggregation in patients with essential hypertension.Japanese heart journal, , Volume: 25, Issue:6, 1984
The role of TXA2 in hypertension.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients.British journal of clinical pharmacology, , Volume: 17 Suppl 1, 1984
Effects of phospholipases A2 from Vipera russelli snake venom on blood pressure, plasma prostacyclin level and renin activity in rats.Toxicon : official journal of the International Society on Toxinology, , Volume: 22, Issue:2, 1984
Release of prostaglandins by the mesenteric artery of the renovascular and spontaneously hypertensive rat.Canadian journal of physiology and pharmacology, , Volume: 62, Issue:1, 1984
Increased thromboxane A2 production but normal prostacyclin by the placenta in hypertensive pregnancies.Prostaglandins, , Volume: 27, Issue:1, 1984
Evidence that prostacyclin deficiency is a specific feature in preeclampsia.American journal of obstetrics and gynecology, , Mar-15, Volume: 148, Issue:6, 1984
Differing effects of two angiotensin converting enzyme inhibitors, captopril and CI-906, on diuresis and the urinary excretion of kallikrein and prostaglandins in spontaneously hypertensive rats.Scandinavian journal of urology and nephrology. Supplementum, , Volume: 79, 1984
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Urinary 6-ketoprostaglandin F1 alpha in genetically hypertensive rats of the Lyon strain.Clinical science (London, England : 1979), , Volume: 66, Issue:4, 1984
Responses of urinary 6-keto-prostaglandin F1 alpha to furosemide administration test in patients with essential hypertension.Nihon Jinzo Gakkai shi, , Volume: 26, Issue:9, 1984
[Effect of psychological stress on the activity of the sympathetic-adrenal system and blood levels of PGE2, PGF2 alpha and 6-keto-PGF1 alpha in patients with primary arterial hypertension].Polskie Archiwum Medycyny Wewnetrznej, , Volume: 72, Issue:4, 1984
Plasma prostaglandins during the intravenous infusion of angiotensin II in pregnant women.American journal of obstetrics and gynecology, , Dec-15, Volume: 150, Issue:8, 1984
PGE2, 6-O-PGF1 alpha and sodium balance in essential hypertensive patients.Prostaglandins, leukotrienes, and medicine, , Volume: 15, Issue:3, 1984
Leukotriene D4: divergent cardiovascular and sympathetic effects in spontaneously hypertensive and normotensive Wistar-Kyoto rats.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Levels of plasma 6-keto-PGF1 alpha in normotensive and essential hypertensive males with and without a family history of hypertension.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:1, 1983
Renin-angiotensin system and prostacyclin biosynthesis in streptozotocin diabetic rats.European journal of pharmacology, , Oct-14, Volume: 94, Issue:1-2, 1983
Plasma levels of 6-keto-prostaglandin F1 alpha in normotensive subjects and patients with essential hypertension.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
Plasma levels of 6-keto-prostaglandin F1 alpha in normotensive subjects and patients with essential hypertension.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:4, 1983
Responses to furosemide in normotensive and hypertensive subjects.Clinical pharmacology and therapeutics, , Volume: 34, Issue:5, 1983
Effect of aging on 6-keto-PGF1 alpha levels in normotensive and essential hypertensive males.Japanese circulation journal, , Volume: 47, Issue:3, 1983
Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:2, 1983
Imbalanced prostacyclin and thromboxane A2 production in essential hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Effects of norepinephrine infusion on systemic hemodynamics and plasma 6-keto-prostaglandin F1 alpha in normotensive subjects and patients with essential hypertension.Japanese circulation journal, , Volume: 46, Issue:5, 1982
Plasma prostanoids in pregnancy-induced hypertension.British journal of obstetrics and gynaecology, , Volume: 89, Issue:8, 1982
Leukotriene D4: cardiovascular and sympathetic effects in spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats.The Journal of pharmacology and experimental therapeutics, , Volume: 223, Issue:1, 1982
Attenuation of the development of hypertension in spontaneously hypertensive rats by the thromboxane synthetase inhibitor, 4'-(imidazol-1-yl) acetophenone.Prostaglandins, , Volume: 24, Issue:2, 1982
[Levels of plasma 6-keto-PGF1 alpha in normotensive and essential hypertensive males with and without a family history of hypertension and effects of aging].Nihon Naibunpi Gakkai zasshi, , Oct-20, Volume: 58, Issue:10, 1982
Angiotensin-converting enzyme inhibition and prostaglandins.The American journal of cardiology, , Apr-21, Volume: 49, Issue:6, 1982
Factors affecting the production of prostacyclin in man.Progress in lipid research, , Volume: 20, 1981
Decrease prostacyclin production: a characteristic of chronic placental insufficiency syndromes.Lancet (London, England), , May-23, Volume: 1, Issue:8230, 1981
Defective synthesis of vasodilator prostaglandins in the spontaneously hypertensive rat.Hypertension (Dallas, Tex. : 1979), , Volume: 6, Issue:2 Pt 2
Inhibition by aspirin of the stimulated PGI2 synthesis after administration of kallikrein to hypertensive patients (new aspects of chemical pathogeny concerning the messenger systems: A and C).Endocrinologie, , Volume: 25, Issue:2
The effect of Enalapril on PGI(2) and NO levels in hypertensive patients.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 66, Issue:5-6
In vivo production of prostaglandin I2 in Dahl salt-sensitive and salt-resistant rats.Hypertension (Dallas, Tex. : 1979), , Volume: 5, Issue:5
Altered aortic production of 6-keto-prostaglandin F1 alpha from aldosterone-salt hypertensive rats.Journal of vascular research, , Volume: 29, Issue:3
[Intracellular electrolytes and selected biochemical parameters in patients with borderline arterial hypertension and positive family history of hypertension].Polski tygodnik lekarski (Warsaw, Poland : 1960), , Volume: 44, Issue:30-31
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.World journal of gastroenterology, , Oct-14, Volume: 13, Issue:38, 2007
[The effect of PGI2 on formation and development of hyperdynamic circulatory state in portal hypertensive rats].Zhonghua wai ke za zhi [Chinese journal of surgery], , Volume: 41, Issue:7, 2003
Endothelial COX-1 and -2 differentially affect reactivity of MVB in portal hypertensive rats.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 283, Issue:3, 2002
Adaptive vasodilatory response after octreotide treatment.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 281, Issue:1, 2001
[Effects of sandostatin on gastric mucosal perfusion in rats with portal hypertensive gastropathy].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, , Volume: 8, Issue:1, 2000
A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury.Journal of gastroenterology and hepatology, , Volume: 14, Issue:7, 1999
Effects of nitric oxide inhibitor on prostacyclin biosynthesis in portal hypertensive rats.Chinese medical journal, , Volume: 112, Issue:6, 1999
Mechanism of overproduction of plasma prostacyclin in portal hypertensive rats.Chinese medical journal, , Volume: 111, Issue:12, 1998
Increased prostacyclin content in gastric mucosa of cirrhotic patients with portal hypertensive gastropathy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:1, 1995
Role of prostacyclin in hemodynamic alterations in conscious rats with extrahepatic or intrahepatic portal hypertension.Hepatology (Baltimore, Md.), , Volume: 18, Issue:3, 1993
Biosynthesis of TXB2 and 6-oxo-PGF1 alpha in the heart and other tissues under pathophysiological conditions.Agents and actions. Supplements, , Volume: 37, 1992
Systemic prostacyclin in cirrhotic patients. Relationship with portal hypertension and changes after intestinal decontamination.Gastroenterology, , Volume: 102, Issue:1, 1992
Evidence for role of prostacyclin as a systemic hormone in portal hypertension.Surgery, , Volume: 109, Issue:2, 1991
Impaired generation of prostaglandins from isolated gastric surface epithelial cells in portal hypertensive rats.Prostaglandins, , Volume: 40, Issue:4, 1990
[Pulmonary vascular changes after portasystemic shunt operation in rats].Nihon Geka Gakkai zasshi, , Volume: 90, Issue:6, 1989
Prostacyclin in the circulation of patients with vascular disorders undergoing surgery.Clinical science (London, England : 1979), , Volume: 71, Issue:6, 1986
Lack of effect of indomethacin on systemic and splanchnic haemodynamics in portal hypertensive rats.Clinical science (London, England : 1979), , Volume: 68, Issue:5, 1985
The effect of prostacyclin on the gastric mucosa in portal-hypertensive rats.Hepato-gastroenterology, , Volume: 49, Issue:43
In search of pulmonary hypertension treatments: Effect of 17β-estradiol on PGIProstaglandins, leukotrienes, and essential fatty acids, , Volume: 172, 2021
Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats.Respiratory research, , 08-04, Volume: 17, Issue:1, 2016
Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.Respiratory research, , 08-31, Volume: 17, Issue:1, 2016
Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics.International journal of molecular medicine, , Volume: 27, Issue:4, 2011
Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin.American journal of medical genetics. Part A, , Volume: 152A, Issue:8, 2010
Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats.Basic research in cardiology, , Volume: 105, Issue:3, 2010
[Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 25, Issue:1, 2009
AAV-PGIS gene transfer improves hypoxia-induced pulmonary hypertension in mice.Biochemical and biophysical research communications, , Nov-23, Volume: 363, Issue:3, 2007
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.Hypertension (Dallas, Tex. : 1979), , Volume: 50, Issue:3, 2007
[Prostacyclin and their metabolites].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 63 Suppl 8, 2005
Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats.Human gene therapy, , Volume: 15, Issue:12, 2004
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs.American journal of physiology. Lung cellular and molecular physiology, , Volume: 284, Issue:2, 2003
[Effect of aspirin on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 19, Issue:4, 2003
Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension.Cardiovascular research, , Volume: 55, Issue:1, 2002
Determination of prostacyclin in plasma through a bioluminescent immunoassay for 6-keto-prostaglandin F1alpha: implication of dosage in patients with primary pulmonary hypertension.Analytical chemistry, , Aug-01, Volume: 74, Issue:15, 2002
Exaggerated hypoxic pulmonary hypertension in endothelin B receptor-deficient rats.American journal of physiology. Lung cellular and molecular physiology, , Volume: 282, Issue:4, 2002
Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock.Critical care medicine, , Volume: 29, Issue:7, 2001
Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.Circulation, , Oct-17, Volume: 102, Issue:16, 2000
[Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension].Terapevticheskii arkhiv, , Volume: 72, Issue:4, 2000
Effects of milrinone on platelet aggregation in swine with pulmonary hypertension.Journal of critical care, , Volume: 15, Issue:3, 2000
Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats.Anesthesia and analgesia, , Volume: 89, Issue:4, 1999
Interferon-alpha elevates pulmonary blood pressure in sheep--the role of thromboxane cascade.European journal of pharmacology, , Apr-09, Volume: 370, Issue:2, 1999
[Effects in tetramethylpyrazine on TXA2 and PGI2 by cardio-pulmonary bypass in congenital heart diseases with pulmonary hypertension patients].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:6, 1998
Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs.Critical care medicine, , Volume: 25, Issue:7, 1997
Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 80, Issue:1, 1996
[Short- and long-term effects of the new oral prostacyclin analogue, beraprost sodium, in patients with severe pulmonary hypertension].Journal of cardiology, , Volume: 27, Issue:4, 1996
Delayed thromboxane or tumor necrosis factor-alpha, but not leukotriene inhibition, attenuates prolonged pulmonary hypertension in endotoxemia.The American journal of the medical sciences, , Volume: 310, Issue:3, 1995
Some humoral factors and their interaction on acute hypoxic pulmonary pressor response.Chinese medical journal, , Volume: 107, Issue:2, 1994
Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 77, Issue:3, 1994
Effects of recombinant human superoxide dismutase on tumor necrosis factor-induced lung injury in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:6, 1993
Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:1, 1993
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:2, 1993
Effects of continuous infusion of nitroglycerin on pulmonary hemodynamics, lung lymph balance, and prostanoid products in the response to endotoxin in awake sheep.Lung, , Volume: 171, Issue:1, 1993
Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease.Circulation, , Volume: 88, Issue:5 Pt 1, 1993
Capsular type-specific polysaccharide partially inhibits group B Streptococcus-induced pulmonary hypertension.The American review of respiratory disease, , Volume: 148, Issue:1, 1993
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.The New England journal of medicine, , Jul-09, Volume: 327, Issue:2, 1992
Effect of endotoxin on hypoxic pulmonary vasoconstriction--the role of prostaglandins and leukotrienes.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:1, 1992
Thromboxane and prostacyclin metabolites in pulmonary hypertension.The New England journal of medicine, , Nov-12, Volume: 327, Issue:20, 1992
Vascular resistance and Kf in normal and PMA-injured rabbit lungs: effects of adenosine.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 71, Issue:2, 1991
Prostanoid production and pulmonary hypertension after fat embolism are not modified by methylprednisolone.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 38, Issue:5, 1991
[Changes of thromboxane A2 (TXA2) and prostacyclin (PGI2) in COPD patients with pulmonary hypertension].Zhonghua nei ke za zhi, , Volume: 30, Issue:2, 1991
Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs.The American review of respiratory disease, , Volume: 143, Issue:4 Pt 1, 1991
Plasma prostanoids in neonates with pulmonary hypertension treated with conventional therapy and with extracorporeal membrane oxygenation.The Journal of thoracic and cardiovascular surgery, , Volume: 101, Issue:6, 1991
Effects of hyperventilation on prostacyclin formation and on pulmonary vasodilation after group B beta-hemolytic streptococci-induced pulmonary hypertension.Pediatric research, , Volume: 29, Issue:3, 1991
Pulmonary hypertensive response to foreign body microemboli.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:2, 1990
[Effect of products released by activated neutrophils on pulmonary arterial pressure].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 13, Issue:5, 1990
The prominent role of thromboxane A2 formation on early pulmonary hypertension induced by oleic acid administration in sheep.Thrombosis research, , Apr-01, Volume: 58, Issue:1, 1990
[Pulmonary vascular changes after portasystemic shunt operation in rats].Nihon Geka Gakkai zasshi, , Volume: 90, Issue:6, 1989
Lipoxygenase and cyclooxygenase blockade by BW755C does not prevent the secondary phase of septic pulmonary hypertension.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 37, Issue:2, 1989
Endogenous formation of prostanoids in neonates with persistent pulmonary hypertension.Archives of disease in childhood, , Volume: 64, Issue:7 Spec No, 1989
[Preliminary observation on plasma level of 5-HT, TXB2 and 6-keto-PGF1 alpha in TEPH].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 10, Issue:5, 1988
Effects of CGS-13080, a thromboxane inhibitor, on pulmonary vascular resistance in patients after mitral valve replacement surgery.Circulation, , Volume: 78, Issue:3 Pt 2, 1988
Selective inhibition of thromboxane synthetase reduces group-B-beta-hemolytic-streptococci-induced pulmonary hypertension in piglets.Developmental pharmacology and therapeutics, , Volume: 11, Issue:5, 1988
6-Ketoprostaglandin F1 alpha and thromboxane B2 in isolated, blood-perfused lungs from monocrotaline pyrrole-treated rats.Journal of toxicology and environmental health, , Volume: 23, Issue:1, 1988
Eicosanoids are involved in the permeability changes but not the pulmonary hypertension after systemic activation of complement.Laboratory investigation; a journal of technical methods and pathology, , Volume: 58, Issue:3, 1988
Direct and indirect effects of leukotriene D4 on the lungs of unanesthetized sheep.Respiration; international review of thoracic diseases, , Volume: 51, Issue:4, 1987
Rat pulmonary artery restructuring and pulmonary hypertension induced by continuous Escherichia coli endotoxin infusion.Laboratory investigation; a journal of technical methods and pathology, , Volume: 56, Issue:2, 1987
Leukotriene antagonist FPL 57231 prevents the acute pulmonary effects of Escherichia coli endotoxin in cats.Circulatory shock, , Volume: 21, Issue:2, 1987
Prostanoids in neonates with persistent pulmonary hypertension.The Journal of pediatrics, , Volume: 110, Issue:3, 1987
6-keto prostaglandin F1 alpha and thromboxane B2 in isolated, buffer-perfused lungs from monocrotaline pyrrole-treated rats.Experimental lung research, , Volume: 12, Issue:3, 1987
Absence of prostaglandin changes associated with protamine administration in patients with pulmonary hypertension.Journal of cardiothoracic anesthesia, , Volume: 1, Issue:5, 1987
Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:4, 1986
Low-dose PGI2 prevents monocrotaline-induced thromboxane production and lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:2, 1986
Effects of a thromboxane antagonist (BM 13.177) during endotoxin-induced pulmonary vasoconstriction in sheep.Clinical physiology (Oxford, England), , Volume: 6, Issue:5, 1986
Effects of verapamil on thromboxane synthesis and pulmonary hypertension in sheep.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 9, Issue:3, 1986
Thromboxane as a mediator of pulmonary dysfunction during intravascular complement activation in sheep.The American review of respiratory disease, , Volume: 133, Issue:2, 1986
Arachidonic acid metabolites as mediators of lung injury during intravascular complement activation.Progress in biochemical pharmacology, , Volume: 20, 1985
Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.The American journal of physiology, , Volume: 248, Issue:6 Pt 2, 1985
Effects of imidazole and indomethacin on fluid balance in isolated sheep lungs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 58, Issue:3, 1985
Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep.The American review of respiratory disease, , Volume: 132, Issue:3, 1985
Extracorporeal membrane oxygenation and congenital diaphragmatic hernia: modification of the pulmonary vasoactive profile.Journal of pediatric surgery, , Volume: 20, Issue:6, 1985
Pulmonary dysfunction secondary to soft-tissue endotoxin.Archives of surgery (Chicago, Ill. : 1960), , Volume: 120, Issue:2, 1985
Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep.Circulation research, , Volume: 52, Issue:1, 1983
Thromboxane mediates acute pulmonary hypertension in sheep extracorporeal perfusion.The American journal of physiology, , Volume: 243, Issue:3, 1982
Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581.The Journal of pharmacology and experimental therapeutics, , Volume: 222, Issue:2, 1982
Thromboxane and pulmonary hypertension following E. coli endotoxin infusion in sheep: effect of an imidazole derivative.Prostaglandins, , Volume: 23, Issue:3, 1982
Effects of renal denervation of the contralateral kidney on blood pressure and sodium and eicosanoid excretion in the chronic phase of two-kidney, one-clip renovascular hypertension in rats.Scandinavian journal of urology and nephrology, , Volume: 39, Issue:1, 2005
[Effect of xueling on relating substances of renal hypertension in rats].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 23, Issue:6, 1998
The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats.The American journal of physiology, , Volume: 257, Issue:2 Pt 2, 1989
Glomerular prostaglandin production in diabetic rats with renovascular hypertension.Kidney international, , Volume: 33, Issue:6, 1988
Dexamethasone attenuates reversal of hypertension in one-kidney, one-clip rats.The American journal of physiology, , Volume: 255, Issue:4 Pt 2, 1988
Vasodepressor phospholipids in reversal of renal hypertension.Agents and actions. Supplements, , Volume: 22, 1987
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.Arzneimittel-Forschung, , Volume: 36, Issue:1, 1986
[Plasma thromboxane B2 and 6-keto-prostaglandin F1-alpha concentrations in patients with essential and renovascular hypertension].Zhonghua xin xue guan bing za zhi, , Volume: 14, Issue:1, 1986
Increased aortic PGI2 and plasma lyso-PAF in the unclipped one-kidney hypertensive rat.The American journal of physiology, , Volume: 251, Issue:6 Pt 2, 1986
Renal prostanoids after unclipping the denervated one-kidney, one-clip hypertensive rat.The American journal of physiology, , Volume: 249, Issue:4 Pt 2, 1985
Dietary modification of platelet and renal prostaglandins.Australian and New Zealand journal of medicine, , Volume: 14, Issue:4, 1984
Urinary 6-keto PGF1 alpha and PGE2 in two kidney-one clip hypertension in the rat.Prostaglandins, leukotrienes, and medicine, , Volume: 13, Issue:3, 1984
Release of prostaglandins by the mesenteric artery of the renovascular and spontaneously hypertensive rat.Canadian journal of physiology and pharmacology, , Volume: 62, Issue:1, 1984
Dissociation of effects of dietary fatty acids on blood pressure and prostanoid metabolism in Goldblatt hypertensive rats.Journal of hypertension, , Volume: 2, Issue:1, 1984
Changes in prostanoid synthesis in response to diet and hypertension in one-kidney, one clip rats.Hypertension (Dallas, Tex. : 1979), , Volume: 7, Issue:6 Pt 1
Trans-10,cis-12-conjugated linoleic acid worsens renal pathology and alters cyclooxygenase derived oxylipins in obesity-associated nephropathy.The Journal of nutritional biochemistry, , Volume: 26, Issue:2, 2015
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.Hypertension (Dallas, Tex. : 1979), , Volume: 50, Issue:3, 2007
The effect of streptozotocin-induced diabetes on PGI2 synthesis by the rat bladder.The Journal of urology, , Volume: 135, Issue:6, 1986
Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats.European journal of pharmacology, , May-05, Volume: 802, 2017
Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial.BMC surgery, , Aug-11, Volume: 17, Issue:1, 2017
Flurbiprofen axetil provides a prophylactic benefit against mesenteric traction syndrome associated with remifentanil infusion during laparotomy.Journal of anesthesia, , Volume: 26, Issue:4, 2012
Remifentanil increases the incidence of mesenteric traction syndrome: preliminary randomized controlled trial.Journal of anesthesia, , Volume: 24, Issue:5, 2010
Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1.European journal of pharmacology, , May-01, Volume: 536, Issue:3, 2006
Role of sensory neuron in reduction of endotoxin-induced hypotension in rats.Critical care medicine, , Volume: 33, Issue:4, 2005
Influences of prostanoids and nitric oxide on post-suspension hypotension in female Sprague-Dawley rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 68, Issue:3, 2003
Baroreceptor and prostanoid control of fetal renal cortical blood flow and plasma renin activity.Reproduction, fertility, and development, , Volume: 13, Issue:2-3, 2001
Effects of inhibitors of the activity of cyclo-oxygenase-2 on the hypotension and multiple organ dysfunction caused by endotoxin: a comparison with dexamethasone.British journal of pharmacology, , Volume: 124, Issue:3, 1998
Haemodynamic and haematologic effects of Acanthaster planci venom in dogs.Toxicon : official journal of the International Society on Toxinology, , Volume: 32, Issue:10, 1994
Transforming growth factor-beta attenuates ischemia-induced alterations in cerebrovascular responses.The American journal of physiology, , Volume: 264, Issue:2 Pt 2, 1993
Superoxide scavengers do not prevent ischemia-induced alteration of cerebral vasodilation in piglets.Pediatric research, , Volume: 33, Issue:2, 1993
Contribution of prostacyclin to D-tubocurarine-induced hypotension in humans.Anesthesiology, , Volume: 72, Issue:1, 1990
The role of prostacyclin in the mesenteric traction syndrome during anesthesia for abdominal aortic reconstructive surgery.Annals of surgery, , Volume: 209, Issue:3, 1989
Prostanoids and pial arteriolar diameter in hypotensive newborn pigs.The American journal of physiology, , Volume: 252, Issue:4 Pt 2, 1987
Maintenance of cerebral circulation during hemorrhagic hypotension in newborn pigs: role of prostanoids.Circulation research, , Volume: 59, Issue:5, 1986
Accumulation of prostacyclin in rat brain during haemorrhagic hypotension--possible role of PGI2 in autoregulation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 4, Issue:1, 1984
Urinary 6-ketoprostaglandin F1 alpha in genetically hypertensive rats of the Lyon strain.Clinical science (London, England : 1979), , Volume: 66, Issue:4, 1984
Prostacyclin biosynthesis and hypotension in relation to complement activation in rabbit endotoxic shock.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs.Thrombosis research, , Apr-01, Volume: 30, Issue:1, 1983
Contribution of complement activation to the rise in blood levels of 6-oxo-prostaglandin F1 alpha during endotoxin-induced hypotension in rabbits.European journal of pharmacology, , Apr-08, Volume: 79, Issue:1-2, 1982
Complement activation and blood levels of 6-oxo-prostaglandin F1alpha during endotoxin-induced hypotension in rabbits.Archives internationales de pharmacodynamie et de therapie, , Volume: 249, Issue:2, 1981
Release of PGE and PGI2 in the pump-perfused dog kidney and associated hypotension.The American journal of physiology, , Volume: 240, Issue:6, 1981
Blood levels of 6-oxo-prostaglandin F 1 alpha during endotoxin-induced hypotension in rabbits.European journal of pharmacology, , Apr-11, Volume: 63, Issue:1, 1980
Endotoxin-induced hypotension and blood levels of 6-keto-prostaglandin F1 alpha.Advances in prostaglandin and thromboxane research, , Volume: 7, 1980
The change of penile blood thromboxane B2 and prostacyclin after intracavernous injection of vasoactive drugs for the treatment of arteriogenic impotence.Proceedings of the National Science Council, Republic of China. Part B, Life sciences, , Volume: 18, Issue:1, 1994
The change of urinary 11-dehydro-thromboxane B2 and 2,3-dinor-6-keto-prostaglandin F1 alpha in arteriogenic impotence.The Journal of urology, , Volume: 148, Issue:2 Pt 1, 1992
Thromboxane B2 production during erection.Andrologia, , Volume: 18, Issue:2
Intrauterine infection and the effects of inflammatory mediators on prostaglandin production by myometrial cells from pregnant women.American journal of obstetrics and gynecology, , Volume: 174, Issue:2, 1996
Non-invasive assessment of the cardiovascular eicosanoids, thromboxane A2 and prostacyclin, in randomly sampled males, with special reference to the influence of inheritance and environmental factors.Clinical science (London, England : 1979), , Volume: 79, Issue:6, 1990
Time course of trauma induced alterations of plasma prostanoid levels in intensive care patients.Progress in clinical and biological research, , Volume: 301, 1989
Abnormal uterus with polycysts, accumulation of uterine prostaglandins, and reduced fertility in mice heterozygous for acyl-CoA synthetase 4 deficiency.Biochemical and biophysical research communications, , Jun-22, Volume: 284, Issue:4, 2001
Retention of intrauterine fetal bone increases menstrual prostaglandins.Obstetrics and gynecology, , Volume: 75, Issue:3 Pt 2, 1990
[Prostanoids of the peritoneal fluid and sterility with or without pelvic lesions (endometriosis, postinfectious adhesions)].Pathologie-biologie, , Volume: 34, Issue:2, 1986
Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay.American journal of obstetrics and gynecology, , Volume: 154, Issue:6, 1986
Peritoneal fluid volume, estrogen, progesterone, prostaglandin, and epidermal growth factor concentrations in patients with and without endometriosis.Obstetrics and gynecology, , Volume: 68, Issue:2, 1986
Peritoneal fluid 6-keto prostaglandin F1 alpha levels in women with endometriosis.American journal of obstetrics and gynecology, , Aug-01, Volume: 152, Issue:7 Pt 1, 1985
Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis.American journal of obstetrics and gynecology, , Jun-15, Volume: 140, Issue:4, 1981
Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats.European journal of pharmacology, , May-05, Volume: 802, 2017
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.Journal of pharmacological sciences, , Volume: 130, Issue:2, 2016
Decrease in inflammatory response does not prevent placental dysfunction after fetal cardiac bypass in goats.The Journal of thoracic and cardiovascular surgery, , Volume: 143, Issue:2, 2012
Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation.Cardiovascular research, , Feb-01, Volume: 81, Issue:2, 2009
Increased responsiveness of human coronary artery endothelial cells in inflammation and coagulation.Mediators of inflammation, , Volume: 2009, 2009
PPAR activators and COX inhibitors selectively block cytokine-induced COX-2 expression and activity in human aortic smooth muscle cells.European journal of pharmacology, , Mar-15, Volume: 606, Issue:1-3, 2009
Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor.British journal of pharmacology, , Volume: 156, Issue:5, 2009
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.Circulation research, , Feb-27, Volume: 104, Issue:4, 2009
Dietary supplementation with trans-11- and trans-12-18 : 1 increases cis-9, trans-11-conjugated linoleic acid in human immune cells, but without effects on biomarkers of immune function and inflammation.The British journal of nutrition, , Volume: 97, Issue:6, 2007
Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells.Molecular and cellular biochemistry, , Volume: 295, Issue:1-2, 2007
Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats.Critical care medicine, , Volume: 34, Issue:7, 2006
Nitric oxide reverses endotoxin-induced inflammatory hyperalgesia via inhibition of prostacyclin production in mice.Pharmacological research, , Volume: 53, Issue:2, 2006
Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2.Carcinogenesis, , Volume: 25, Issue:8, 2004
Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis.Arthritis research & therapy, , Volume: 6, Issue:4, 2004
Contribution of interaction between nitric oxide and cyclooxygenases to the production of prostaglandins in carrageenan-induced inflammation.Anesthesiology, , Volume: 101, Issue:4, 2004
Antithrombin reduces the ischemia/reperfusion-induced spinal cord injury in rats by attenuating inflammatory responses.Thrombosis and haemostasis, , Volume: 91, Issue:1, 2004
Role of human heme oxygenase-1 in attenuating TNF-alpha-mediated inflammation injury in endothelial cells.Journal of cellular biochemistry, , Volume: 87, Issue:4, 2002
Inflammatory response during abdominal and thyroid surgery: a prospective clinical trial on mediator release.Shock (Augusta, Ga.), , Volume: 16, Issue:5, 2001
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin.British journal of pharmacology, , Volume: 126, Issue:6, 1999
The role of prostanoids and nitric oxide in endotoxin-induced hyporesponsiveness of equine digital blood vessels.Equine veterinary journal, , Volume: 31, Issue:3, 1999
Early inflammatory response correlates with the severity of injury.Critical care medicine, , Volume: 24, Issue:7, 1996
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.Prostaglandins, , Volume: 51, Issue:1, 1996
Blunt injury augments interleukin-6 but not tumor necrosis factor in isolated, perfused rat hindlimbs.The Journal of trauma, , Volume: 37, Issue:1, 1994
Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists.British journal of pharmacology, , Volume: 110, Issue:1, 1993
Gastric toxicity and prostaglandin content in rats dosed with two chemically similar, nonsteroidal anti-inflammatory agents.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 202, Issue:2, 1993
Cytokine activation of human macro- and microvessel-derived endothelial cells.Blood cells, , Volume: 19, Issue:2, 1993
Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation.The Journal of pharmacy and pharmacology, , Volume: 45, Issue:8, 1993
Anti-inflammatory and gastrointestinal effects of nabumetone or its active metabolite, 6MNA (6-methoxy-2-naphthylacetic acid): comparison with indomethacin.Agents and actions, , Volume: Spec No, 1992
Evidence of acute inflammatory response in reexpansion pulmonary edema.Chest, , Volume: 101, Issue:1, 1992
Time course of various inflammatory mediators during recurrent endotoxemia.Biochemical pharmacology, , May-28, Volume: 43, Issue:10, 1992
Prostaglandin release by normal and osteomyelitic human bones.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 43, Issue:1, 1991
A comparison of the anti-inflammatory activity of selective 5-lipoxygenase inhibitors with dexamethasone and colchicine in a model of zymosan induced inflammation in the rat knee joint and peritoneal cavity.Agents and actions, , Volume: 32, Issue:3-4, 1991
Effect of misoprostol on concentrations of prostaglandins in synovial fluid.Annals of the rheumatic diseases, , Volume: 50, Issue:11, 1991
Inhibition of prostaglandin production in the inflammatory tissue by loxoprofen-Na, an anti-inflammatory prodrug.Biochemical pharmacology, , Nov-27, Volume: 42, Issue:12, 1991
Systemic lipid peroxidation and inflammation induced by thermal injury persists into the post-resuscitation period.The Journal of trauma, , Volume: 30, Issue:1, 1990
Essential fatty acid deficiency inhibits early but not late leukocyte infiltration in rabbit myocardial infarcts.Prostaglandins, , Volume: 38, Issue:1, 1989
Development of equine models of inflammation. The Ciba-Geigy Prize for Research in Animal Health.The Veterinary record, , May-30, Volume: 120, Issue:22, 1987
Actions of BW540C in an equine model of acute inflammation: a preliminary study.The veterinary quarterly, , Volume: 9, Issue:2, 1987
Effects of a phenylbutazone paste in ponies: model of acute nonimmune inflammation.American journal of veterinary research, , Volume: 47, Issue:11, 1986
Compartmentalized regulation of macrophage arachidonic acid metabolism.The Journal of experimental medicine, , Mar-01, Volume: 163, Issue:3, 1986
Lack of correlation between in vitro and in vivo effects of low density lipoprotein on the inflammatory activity of monosodium urate crystals.Annals of the rheumatic diseases, , Volume: 45, Issue:8, 1986
Studies of eicosanoid production in the air pouch model of synovial inflammation.Agents and actions, , Volume: 18, Issue:3-4, 1986
A comparison of the acute inflammatory response in adrenalectomised and sham-operated rats.British journal of pharmacology, , Volume: 87, Issue:1, 1986
Ibuprofen modifies the inflammatory response of the murine lung to Pseudomonas aeruginosa.European journal of respiratory diseases, , Volume: 67, Issue:2, 1985
Infectious-inflammatory changes in cyclic AMP levels and in their regulation by prostaglandins in human peritoneal macrophages.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Involvement of arachidonic acid metabolites in acute inflammation: detection of 6-keto-PGF1 alpha, thromboxane B2 and PGD2 in rat pleurisy induced by phorbol myristate acetate.Japanese journal of pharmacology, , Volume: 39, Issue:2, 1985
Arachidonic acid metabolites in carrageenin-induced equine inflammatory exudate.Journal of veterinary pharmacology and therapeutics, , Volume: 7, Issue:1, 1984
Inhibition of PG production by MDL 035, a new non-steroidal non-acidic anti-inflammatory compound, in rat gastric mucosa and inflammatory exudate.Pharmacological research communications, , Volume: 16, Issue:8, 1984
Influence of phenylbutazone on eicosanoid levels in equine acute inflammatory exudate.The Cornell veterinarian, , Volume: 74, Issue:3, 1984
Increased levels of 6-oxo-PGF1 alpha in human skin following ultraviolet B irradiation.British journal of clinical pharmacology, , Volume: 13, Issue:3, 1982
Prostaglandins E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 levels in carrageenin-induced inflammatory exudates in the rat air-pouch granuloma.Prostaglandins and medicine, , Volume: 2, Issue:4, 1979
Prostaglandin production by human chorion laeve cells in response to inflammatory mediators.Placenta, , Volume: 12, Issue:4
Influence of annexin A7 on insulin sensitivity of cellular glucose uptake.Pflugers Archiv : European journal of physiology, , Volume: 467, Issue:4, 2015
[Disturbed synthesis of eicosanoids in patients with metabolic syndrome].Klinicheskaia meditsina, , Volume: 88, Issue:3, 2010
[Insulin resistance and effects of intravenous acute saline load on renal production of prostaglandin I2 and thromboxane A2 in salt-sensitive hypertensive patients].Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, , Volume: 25, Issue:1, 2005
Enhanced endothelin activity prevents vasodilation to insulin in insulin resistance.Hypertension (Dallas, Tex. : 1979), , Volume: 40, Issue:1, 2002
Percutaneous transluminal angioplasty increases thromboxane A2 production in claudicants.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:5, 1997
Reduction by indobufen of neutrophil activation in peripheral arterial occlusive disease.Journal of cardiovascular pharmacology, , Volume: 27, Issue:3, 1996
Excretion of thromboxane A2 and prostacyclin metabolites during treadmill exercise in patients with intermittent claudication.Clinical physiology (Oxford, England), , Volume: 8, Issue:3, 1988
A windowless peek into the brain.Nature methods, , Volume: 11, Issue:10, 2014
Procoagulant and prothrombotic responses of human endothelium to indomethacin and endotoxin in vitro. Relevance to non-steroidal anti-inflammatory drug enteropathy.Scandinavian journal of gastroenterology, , Volume: 30, Issue:1, 1995
Effect of immunization with prostaglandin metabolites on gastrointestinal ulceration.The American journal of physiology, , Volume: 255, Issue:6 Pt 1, 1988
Discordant effect of aspirin and indomethacin on intestinal tumor burden in Apc(Min/+)mice.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:5, 2000
Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice.The Journal of nutrition, , Volume: 130, Issue:10, 2000
Some features in prostaglandin synthesis of the cancer cells which metastasized into liver from intestinal cancer lesions.The Tohoku journal of experimental medicine, , Volume: 170, Issue:2, 1993
[Effect of the recombinant staphylokinase on pancreatic ischemia in severe acute pancreatitis of rats].Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, , Volume: 19, Issue:8, 2007
Antithrombin III pretreatment reduces neutrophil recruitment into the lung and skeletal muscle tissues in the rat model of bilateral lower limb ischemia and reperfusion: a pilot study.Acta anaesthesiologica Scandinavica, , Volume: 49, Issue:8, 2005
[Prostacyclin and their metabolites].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 63 Suppl 8, 2005
Role of peroxynitrite in the process of vascular tone regulation by nitric oxide and prostanoids--a nanotechnological approach.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 72, Issue:2, 2005
Antithrombin reduces the ischemia/reperfusion-induced spinal cord injury in rats by attenuating inflammatory responses.Thrombosis and haemostasis, , Volume: 91, Issue:1, 2004
Antithrombin reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation through promotion of prostacyclin production.Blood, , Apr-15, Volume: 101, Issue:8, 2003
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Distinct role of intrarenal cyclooxygenase-1/2 in chronic unilateral renal ischemia.Nephron, , Volume: 92, Issue:1, 2002
Effects of FK3311 on pulmonary ischemia-reperfusion injury in a canine model.The Journal of surgical research, , Volume: 95, Issue:2, 2001
Prostanoid metabolism in porcine liver transplantation: influence of warm ischemia.Transplantation proceedings, , Volume: 28, Issue:3, 1996
Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model.Transplantation, , May-27, Volume: 61, Issue:10, 1996
Prostacyclin and thromboxane A2 synthesis are increased in acute lower limb ischaemia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 55, Issue:6, 1996
The effects of thromboxane A2 synthetase inhibitor (OKY-046) on complete hepatic ischemia in rats with obstructive jaundice.Surgery today, , Volume: 26, Issue:1, 1996
Leukocyte and platelet depletion protects the liver from damage induced by cholestasis and ischemia-reperfusion in the dog.Scandinavian journal of gastroenterology, , Volume: 31, Issue:2, 1996
Acute mesenteric ischemia/reperfusion down regulates renal PGE2 synthesis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 52, Issue:1, 1995
Role of thromboxane A2 and prostacyclin in uninephrectomy-induced attenuation of ischemic renal injury.Kidney international, , Volume: 48, Issue:5, 1995
Role of xanthine oxidase and eicosanoids in development of pancreatic ischemia-reperfusion injury.Inflammation, , Volume: 19, Issue:4, 1995
The protective effect of thromboxane A2 synthetase inhibitor against ischemic liver injury.Surgery today, , Volume: 24, Issue:5, 1994
Effects of leukocyte and platelet depletion on ischemia--reperfusion injury to dog pancreas.Gastroenterology, , Volume: 107, Issue:4, 1994
Renal protective effect of liposomed superoxide dismutase in an experimental warm ischemia model.Transplant international : official journal of the European Society for Organ Transplantation, , Volume: 7 Suppl 1, 1994
Arachidonate metabolism in ischemia-reperfusion associated with pancreas transplantation.Journal of lipid mediators and cell signalling, , Volume: 9, Issue:2, 1994
Brief mesenteric ischemia increases PGE2, but not PGI2, in intestinal lymph of cats.The American journal of physiology, , Volume: 266, Issue:5 Pt 2, 1994
Hepatoprotection by a PGI2 analogue in complete warm ischemia of the pig liver. Prostanoid release from the reperfused liver.Transplantation, , Oct-27, Volume: 58, Issue:8, 1994
Role of the bronchial circulation in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 76, Issue:1, 1994
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
Platelet-activating factor as a vasodepressive mediator of liver ischemia.Transplantation proceedings, , Volume: 25, Issue:6, 1993
Gangliosides stimulate synthesis of prostaglandin E2 and prostacyclin in fetal rat brain hemispheres after episodes of global intrauterine ischemia.Journal of neuroscience research, , Nov-01, Volume: 36, Issue:4, 1993
Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:1, 1993
[Effect of electroacupuncture at "taixi" point on plasma thromboxane A2 and prostacyclin in the rabbit with renal ischemia].Zhen ci yan jiu = Acupuncture research, , Volume: 18, Issue:3, 1993
Pancreas prostanoid production in ischemia and reperfusion.Prostaglandins, , Volume: 43, Issue:5, 1992
A thromboxane A2 synthase inhibitor, DP-1904, prevents rat renal injury.European journal of pharmacology, , Feb-14, Volume: 193, Issue:3, 1991
The influence of arachidonic acid metabolites on leukocyte activation and skeletal muscle injury after ischemia and reperfusion.Journal of vascular surgery, , Volume: 14, Issue:4, 1991
Altered levels of tissue and urinary prostacyclin in rats subjected to pancreas transplantation.Prostaglandins, , Volume: 41, Issue:6, 1991
Prostaglandins and pancreas transplantation.Prostaglandins, , Volume: 41, Issue:6, 1991
Beneficial effect of superoxide dismutase (SOD) on erythrocyte trapping and 6-keto-PGF1 alpha TxB2 ratio after ischemia-reperfusion in kidney transplantation.Transplantation proceedings, , Volume: 22, Issue:5, 1990
Ischemia-reperfusion injury in an ischemic rat liver model: relationship between oxygen-derived free radicals and prostaglandins.Transplantation proceedings, , Volume: 22, Issue:2, 1990
Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited.Annals of surgery, , Volume: 209, Issue:2, 1989
Effect of PGI2 and thromboxane antagonist on liver ischemic injury.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, , Volume: 21, Issue:3-4, 1989
Postischemic renal injury is mediated by neutrophils and leukotrienes.The American journal of physiology, , Volume: 256, Issue:5 Pt 2, 1989
Limb ischemia-induced increase in permeability is mediated by leukocytes and leukotrienes.Annals of surgery, , Volume: 208, Issue:6, 1988
Vasoactive prostaglandins in the impending no-reflow state: evidence for a primary disturbance in microvascular tone.Plastic and reconstructive surgery, , Volume: 81, Issue:5, 1988
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.Surgery, gynecology & obstetrics, , Volume: 165, Issue:5, 1987
Renal hemodynamic effects of therapeutic plasma levels of sulindac sulfide during hemorrhage.Kidney international, , Volume: 29, Issue:2, 1986
Inhibition of thromboxane biosynthesis in splanchnic ischemia shock.Circulatory shock, , Volume: 18, Issue:2, 1986
Enhanced prostaglandin synthesis due to phospholipid breakdown in ischemic-reperfused myocardium. Control of its production by a phospholipase inhibitor or free radical scavengers.Journal of molecular and cellular cardiology, , Volume: 18, Issue:9, 1986
Prostacyclin and thromboxane A2 moderate postischemic renal failure.Surgery, , Volume: 98, Issue:2, 1985
Prostacyclin production reduced in diabetics with vascular complications.Japanese journal of medicine, , Volume: 24, Issue:3, 1985
Thromboxane A2 moderates permeability after limb ischemia.Annals of surgery, , Volume: 202, Issue:5, 1985
Inhibition of ischemia-induced thromboxane synthesis in man.The Journal of trauma, , Volume: 24, Issue:5, 1984
Prostacyclin and thromboxane in non-insulin dependent diabetes: the chlorpropamide alcohol flush reaction revisited.Clinical science (London, England : 1979), , Volume: 67, Issue:6, 1984
Changes of plasma 6-keto-PGF1 alpha and thromboxane B2 levels and platelet aggregation after tourniquet ischemia on the upper limb in normal subjects and patients with ischemic heart disease.Japanese circulation journal, , Volume: 46, Issue:7, 1982
Forearm ischaemia as a test of prostacyclin production: studies in normal subjects and in patients with diabetes mellitus.Prostaglandins and medicine, , Volume: 6, Issue:6, 1981
Lack of effect of ischemia and dipyridamole on prostacyclin production in arteriosclerosis obliterans.Prostaglandins, , Volume: 21, Issue:5, 1981
Inhibition of thromboxane A2 synthesis by OKY-046 attenuates ischemia and reperfusion injury of the liver.Transplantation proceedings, , Volume: 31, Issue:1-2
[Cardio- and hemodynamics of dogs during the development of postischemic shock reaction].Fiziologicheskii zhurnal, , Volume: 35, Issue:4
Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome.The British journal of nutrition, , Jul-14, Volume: 110, Issue:1, 2013
Activation of sensory neurons reduces ischemia/reperfusion-induced acute renal injury in rats.Anesthesiology, , Volume: 110, Issue:2, 2009
Dietary soy protein reduces early renal disease progression and alters prostanoid production in obese fa/fa Zucker rats.The Journal of nutritional biochemistry, , Volume: 19, Issue:4, 2008
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.Journal of hypertension, , Volume: 26, Issue:12, 2008
Attenuation of ciclosporin-induced nephrotoxicity by dietary supplementation of seal oil in Sprague-Dawley rats.The Journal of pharmacy and pharmacology, , Volume: 57, Issue:11, 2005
Induction of microsomal prostaglandin E2 synthase in the macula densa in children with hypokalemic salt-losing tubulopathies.Pediatric research, , Volume: 55, Issue:2, 2004
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.The Journal of nutritional biochemistry, , Volume: 14, Issue:8, 2003
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.The Journal of nutritional biochemistry, , Volume: 14, Issue:11, 2003
Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide?Kidney & blood pressure research, , Volume: 24, Issue:2, 2001
Abnormal prostanoid metabolism in lupus nephritis and the effects of a thromboxane A2 synthetase inhibitor, DP-1904.Lupus, , Volume: 5, Issue:2, 1996
Amelioration of radiation nephropathy by acetylsalicylic acid.International journal of radiation biology, , Volume: 67, Issue:5, 1995
Prostanoids and cyclosporin-mediated nephrotoxicity in rats: a critical appraisal.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 52, Issue:1, 1995
Reduction of cyclosporine-induced nephrotoxicity by cilastatin following clinical heart transplantation.Transplantation, , Mar-27, Volume: 57, Issue:6, 1994
Tacrolimus (FK506)-induced nephrotoxicity in spontaneous hypertensive rats.The Journal of toxicological sciences, , Volume: 19, Issue:4, 1994
Alleviation of experimental cyclosporin A nephrotoxicity by low dose aspirin in the rat.Biochemical pharmacology, , Dec-03, Volume: 46, Issue:11, 1993
Thromboxane synthesis inhibition increases renal prostacyclin and prevents renal disease progression in rats with remnant kidney.Journal of the American Society of Nephrology : JASN, , Volume: 1, Issue:5, 1990
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.Annals of surgery, , Volume: 212, Issue:6, 1990
Effects of sulindac and naproxen on prostaglandin excretion in patients with impaired renal function and rheumatoid arthritis.The American journal of medicine, , Volume: 89, Issue:3, 1990
Compared effects of isoxicam and indomethacin on the urinary excretion of prostaglandins in degenerative articular diseases.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 38, Issue:2, 1989
[Preventive effect of OP-41483-alpha-CD on cyclosporine A-induced renal tubular and arterial damages].Nihon Geka Gakkai zasshi, , Volume: 90, Issue:2, 1989
Prevention of acute cyclosporine A nephrotoxicity by a thromboxane synthetase inhibitor.Transplantation proceedings, , Volume: 20, Issue:2 Suppl 2, 1988
Selective enhancement of thromboxane in macrophages and kidneys in cyclosporine-induced nephrotoxicity. Dietary protection by fish oil.Transplantation, , Volume: 45, Issue:1, 1988
Influence of renal insufficiency on the pharmacokinetics of cicletanine and its effects on the urinary excretion of electrolytes and prostanoids.British journal of clinical pharmacology, , Volume: 25, Issue:3, 1988
[Measurement of urinary TXB2, 6-keto-PGF1 alpha by radioimmunoassay and its clinical significance].Zhonghua nei ke za zhi, , Volume: 26, Issue:12, 1987
Prostaglandin levels in human renal venous blood during renal arteriography.European journal of radiology, , Volume: 6, Issue:2, 1986
Renin-angiotensin system and glomerular prostaglandins in early nephrotoxicity of ciclosporin.Contributions to nephrology, , Volume: 51, 1986
Renal hemodynamic effects of therapeutic plasma levels of sulindac sulfide during hemorrhage.Kidney international, , Volume: 29, Issue:2, 1986
[High-protein diet and high-grade proteinuria aggravate the progression of chronic renal failure in rats].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 5, Issue:3, 2007
Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients.Renal failure, , Volume: 25, Issue:4, 2003
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Urinary excretion of vasoactive substances in chronic renal failure.Clinical nephrology, , Volume: 55, Issue:5, 2001
Effects of flaxseed and flax oil diets in a rat-5/6 renal ablation model.American journal of kidney diseases : the official journal of the National Kidney Foundation, , Volume: 25, Issue:2, 1995
Increased production of prostacyclin after injury to the microvasculature in uraemic patients.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, , Mar-21, Volume: 81, Issue:6, 1992
[Treatment of chronic renal failure with Oenothera beinnis L in rats with subtotal nephrectomy].Zhonghua nei ke za zhi, , Volume: 31, Issue:1, 1992
Role of renal sympathetic nerve activity in renal failure associated with obstructive jaundice in the rat.American journal of surgery, , Volume: 161, Issue:6, 1991
[The level of thromboxane A2 and prostacyclin in patients with chronic kidney failure undergoing hemodialysis].Terapevticheskii arkhiv, , Volume: 63, Issue:6, 1991
Effect of conjugated estrogens on platelet function and prostacyclin generation in CRF.Kidney international, , Volume: 38, Issue:6, 1990
[The changes in serum TXB2 and 6-keto-PGF1 alpha in 62 cases with renal disease].Zhonghua nei ke za zhi, , Volume: 28, Issue:1, 1989
Evidence for an increased generation of prostacyclin in the microvasculature and an impairment of the platelet alpha-granule release in chronic renal failure.Thrombosis and haemostasis, , Oct-31, Volume: 60, Issue:2, 1988
Glomerular and hormonal responses to dietary protein intake in human renal disease.The American journal of physiology, , Volume: 253, Issue:6 Pt 2, 1987
Suppression of plasma renin activity by cyclosporine.The American journal of medicine, , Volume: 83, Issue:1, 1987
Evidence of prostacyclin deficiency in the syndrome of hyporeninemic hypoaldosteronism.The New England journal of medicine, , Apr-17, Volume: 314, Issue:16, 1986
Effects of sulindac on renal function and prostaglandin synthesis in patients with moderate chronic renal insufficiency.Clinical science (London, England : 1979), , Volume: 70, Issue:5, 1986
Prostanoids and renal failure. A hypothetical role for prostanoids in progressive renal disease.Contributions to nephrology, , Volume: 50, 1986
Increased synthesis of systemic prostacyclin in cirrhotic patients.Gastroenterology, , Volume: 90, Issue:3, 1986
Stimulation of peritoneal synthesis of vasoactive prostaglandins during peritonitis in patients on continuous ambulatory peritoneal dialysis.European journal of clinical investigation, , Volume: 15, Issue:1, 1985
Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure.Thrombosis research, , Apr-01, Volume: 30, Issue:1, 1983
Prostacyclin and thromboxane release from human peritoneal macrophages.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 12, 1983
Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:3, 1983
Prostacyclin synthesis is stimulated by a serum factor formed during coagulation.Thrombosis and haemostasis, , Feb-28, Volume: 49, Issue:1, 1983
Neutrophil adhesiveness during prostacyclin and heparin hemodialysis.Blood, , Volume: 60, Issue:4, 1982
Prostacyclin and thromboxane in chronic uremia: effect of hemodialysis.Clinical nephrology, , Volume: 18, Issue:2, 1982
Prostacyclin substitution for heparin in long-term hemodialysis.The American journal of medicine, , Volume: 73, Issue:5, 1982
Platelet microaggregates and release of endogenous prostacyclin during the initial phase of haemodialysis.Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, , Volume: 18, 1981
Uremic levels of oxalic acid suppress replication and migration of human endothelial cells.Arteriosclerosis (Dallas, Tex.), , Volume: 10, Issue:2
Changes in endothelial vasoactive substances under recombinant human erythropoietin therapy in hemodialysis patients.ASAIO transactions, , Volume: 37, Issue:3
Suppression of the nitric oxide pathway in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-signaling inhibitors.Hypertension (Dallas, Tex. : 1979), , Volume: 56, Issue:6, 2010
Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2.Clinical science (London, England : 1979), , Volume: 95, Issue:1, 1998
Prostaglandin levels in human renal venous blood during renal arteriography.European journal of radiology, , Volume: 6, Issue:2, 1986
Altered 1-14C arachidonic acid metabolism in arterial wall from patients with renal cell carcinoma.The Journal of urology, , Volume: 135, Issue:5, 1986
[Changes of prostaglandins in kidney tissue in gentamicin-induced acute renal tubular injury in rats].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 20, Issue:1, 1998
Inhibition of thromboxane (Tx) synthesis by free radical scavengers.The Journal of trauma, , Volume: 28, Issue:4, 1988
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.Surgery, gynecology & obstetrics, , Volume: 165, Issue:5, 1987
Increased thromboxane A2 production at primary tumor site in metastasizing squamous cell carcinoma of the larynx.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:1, 1993
Prostaglandins in squamous cell carcinoma of the larynx: tumor and peritumor synthesis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Eicosanoids production in endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:4, 1992
Prostacyclin and thromboxane synthesis by endometrial cancer and leiomyomas.Prostaglandins, , Volume: 39, Issue:3, 1990
Prostaglandin production by human myometrium, uterine cervix and leiomyoma.Prostaglandins, leukotrienes, and medicine, , Volume: 29, Issue:1, 1987
Leiomyomas release prostaglandins.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:1, 1985
Activated neutrophils impair gastric cytoprotection role of neutrophil elastase.Digestive diseases and sciences, , Volume: 45, Issue:6, 2000
Gastric prostacyclin (PGI2) prevents stress-induced gastric mucosal injury in rats primarily by inhibiting leukocyte activation.Prostaglandins & other lipid mediators, , Volume: 57, Issue:5-6, 1999
Antithrombin III (AT III) prevents LPS-induced pulmonary vascular injury: novel biological activity of AT III.Seminars in thrombosis and hemostasis, , Volume: 23, Issue:6, 1997
Novel role of prostacyclin in stress-induced gastric mucosal lesion formation in rats.The Journal of laboratory and clinical medicine, , Volume: 129, Issue:6, 1997
Leukocyte depletion and ONO-5046, a specific inhibitor of granulocyte elastase, prevent a stress-induced decrease in gastric prostaglandin I2 in rats.Biochemical and biophysical research communications, , Feb-03, Volume: 231, Issue:1, 1997
Haemodynamic and haematologic effects of Acanthaster planci venom in dogs.Toxicon : official journal of the International Society on Toxinology, , Volume: 32, Issue:10, 1994
Platelet activating factor involvement in splanchnic artery occlusion shock in rats.European journal of pharmacology, , Jan-03, Volume: 192, Issue:1, 1991
Influence of an omega-3 fatty acid-enriched ration on in vivo responses of horses to endotoxin.American journal of veterinary research, , Volume: 52, Issue:4, 1991
Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:4, 1986
Role of cyclooxygenase isoforms in encephalopathy of cirrhotic rats.Journal of the Chinese Medical Association : JCMA, , Volume: 79, Issue:11, 2016
Roles of anandamide in the hepatic microcirculation in cirrhotic rats.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 290, Issue:2, 2006
Cyclooxygenase-derived products modulate the increased intrahepatic resistance of cirrhotic rat livers.Hepatology (Baltimore, Md.), , Volume: 37, Issue:1, 2003
Adaptive vasodilatory response after octreotide treatment.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 281, Issue:1, 2001
Plasma iPGE2 and i6-keto PGF1 alpha in the course of liver cirrhosis.Prostaglandins, , Volume: 53, Issue:1, 1997
Increased prostacyclin content in gastric mucosa of cirrhotic patients with portal hypertensive gastropathy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:1, 1995
The role of systemic prostaglandins during human liver transplantation.Annals of the New York Academy of Sciences, , Jun-17, Volume: 723, 1994
Indomethacin-induced renal dysfunction in patients with well-compensated cirrhosis.Gastroenterology, , Volume: 104, Issue:3, 1993
Systemic prostacyclin in cirrhotic patients. Relationship with portal hypertension and changes after intestinal decontamination.Gastroenterology, , Volume: 102, Issue:1, 1992
[Studies on plasma beta-thromboglobulin, thromboxane A2, prostaglandin I2 concentration and platelet count in liver diseases].Zhonghua nei ke za zhi, , Volume: 31, Issue:2, 1992
Renal effects of imidazole-2-hydroxybenzoate in patients with compensated liver cirrhosis.International journal of clinical pharmacology, therapy, and toxicology, , Volume: 30, Issue:7, 1992
Renal prostacyclin influences renal function in non-azotemic cirrhotic patients treated with furosemide.Journal of hepatology, , Volume: 12, Issue:2, 1991
[Changes in arterial thromboxane B2 and 6-keto-prostaglandin-F1 alpha levels in cirrhotic and non-cirrhotic patients after hepatectomy].Nihon Geka Gakkai zasshi, , Volume: 91, Issue:3, 1990
[Measurement of urinary TXB2, 6-keto-PGF1 alpha by radioimmunoassay and its clinical significance].Zhonghua nei ke za zhi, , Volume: 26, Issue:12, 1987
Urinary excretion of 6-keto-prostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 in cirrhosis with ascites. Relationship to functional renal failure (hepatorenal syndrome).Journal of hepatology, , Volume: 3, Issue:1, 1986
Increased synthesis of systemic prostacyclin in cirrhotic patients.Gastroenterology, , Volume: 90, Issue:3, 1986
Renal prostaglandins in cirrhosis of the liver.Clinical science (London, England : 1979), , Volume: 70, Issue:5, 1986
Determination of 2,3-dinor-6-ketoprostaglandin F1 alpha in urine samples by liquid chromatography and radioimmunoassay.Journal of chromatography, , Dec-19, Volume: 383, Issue:2, 1986
Sulindac reduces the urinary excretion of prostaglandins and impairs renal function in cirrhosis with ascites.Nephron, , Volume: 42, Issue:4, 1986
Effect of spironolactone on renal prostaglandin excretion in patients with liver cirrhosis and ascites.Journal of hepatology, , Volume: 3, Issue:2, 1986
Altered renal and platelet arachidonic acid metabolism in cirrhosis.Gastroenterology, , Volume: 90, Issue:2, 1986
Release of prostanoids into the portal and hepatic vein in patients with chronic liver disease.Hepatology (Baltimore, Md.), , Volume: 6, Issue:5
Prostacyclin decreases splanchnic vascular contractility in cirrhotic rats.Hepatobiliary & pancreatic diseases international : HBPD INT, , Volume: 13, Issue:4, 2014
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Intrarenal thromboxane A2 generation reduces the furosemide-induced sodium and water diuresis in cirrhosis with ascites.Gastroenterology, , Volume: 95, Issue:4, 1988
Effects of sulindac and ibuprofen in patients with cirrhosis and ascites. An explanation for the renal-sparing effect of sulindac.Gastroenterology, , Volume: 90, Issue:1, 1986
Effect of chronic CB1 cannabinoid receptor antagonism on livers of rats with biliary cirrhosis.Clinical science (London, England : 1979), , Volume: 112, Issue:10, 2007
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction.Hepatology (Baltimore, Md.), , Volume: 18, Issue:1, 1993
Role of prostacyclin in hemodynamic alterations in conscious rats with extrahepatic or intrahepatic portal hypertension.Hepatology (Baltimore, Md.), , Volume: 18, Issue:3, 1993
Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats.Critical care medicine, , Volume: 34, Issue:7, 2006
Contribution of capsaicin-sensitive sensory neurons to antithrombin-induced reduction of ischemia/reperfusion-induced liver injury in rats.Thrombosis and haemostasis, , Volume: 93, Issue:1, 2005
The role of the spleen, especially regarding changes in both thromboxane A2 and the remnant liver dysfunction after extensive hepatectomy.Surgery today, , Volume: 29, Issue:2, 1999
Prostanoids and free radicals in Cl4C-induced hepatotoxicity in rats: effect of astilbin.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:4, 1997
Hepatocellular dysfunction occurs earlier than the onset of hyperdynamic circulation during sepsis.Shock (Augusta, Ga.), , Volume: 3, Issue:1, 1995
[Pathophysiological basis of 3 subtypes in ganfeng neidong syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:7, 1993
[Studies on plasma beta-thromboglobulin, thromboxane A2, prostaglandin I2 concentration and platelet count in liver diseases].Zhonghua nei ke za zhi, , Volume: 31, Issue:2, 1992
[Prostacyclin and thromboxane synthesis in liver tissue in chronic liver diseases].Zeitschrift fur medizinische Laboratoriumsdiagnostik, , Volume: 31, Issue:6, 1990
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.Annals of surgery, , Volume: 212, Issue:6, 1990
Renal function in fulminant hepatic failure: haemodynamics and renal prostaglandins.Gut, , Volume: 28, Issue:12, 1987
Importance of renal prostaglandins in control of renal function after chronic ligation of the common bile duct in dogs.The Journal of laboratory and clinical medicine, , Volume: 103, Issue:4, 1984
[Protective effect of ligustrazine and propofol on peri-operational liver ischemia-reperfusion injury].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 26, Issue:3, 2006
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.International journal of gastrointestinal cancer, , Volume: 32, Issue:1, 2002
NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines.International journal of cancer, , Jun-10, Volume: 99, Issue:5, 2002
Comparison of prostanoids and their precursor fatty acids in human hepatocellular carcinoma and noncancerous reference tissues.The Journal of surgical research, , Volume: 54, Issue:1, 1993
Some features in prostaglandin synthesis of the cancer cells which metastasized into liver from intestinal cancer lesions.The Tohoku journal of experimental medicine, , Volume: 170, Issue:2, 1993
[Studies on plasma beta-thromboglobulin, thromboxane A2, prostaglandin I2 concentration and platelet count in liver diseases].Zhonghua nei ke za zhi, , Volume: 31, Issue:2, 1992
[Changes in arterial thromboxane B2 and 6-keto-prostaglandin-F1 alpha levels in cirrhotic and non-cirrhotic patients after hepatectomy].Nihon Geka Gakkai zasshi, , Volume: 91, Issue:3, 1990
Urinary excretion of prostaglandins and renal function after hepatic resection.Hepato-gastroenterology, , Volume: 44, Issue:15
Role of neutrophil elastase in development of pulmonary vascular injury and septic shock in rats.Shock (Augusta, Ga.), , Volume: 30, Issue:4, 2008
Selective thromboxane A2 synthase inhibition by OKY-046 prevents cardiopulmonary dysfunction after ovine smoke inhalation injury.Anesthesiology, , Volume: 102, Issue:5, 2005
Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs.The Journal of pharmacy and pharmacology, , Volume: 56, Issue:4, 2004
Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock.Critical care medicine, , Volume: 29, Issue:7, 2001
Effects of low-dose Beraprost sodium, a stable prostaglandin I2 analogue, on reperfusion injury to rabbit lungs.American journal of respiratory and critical care medicine, , Volume: 158, Issue:5 Pt 1, 1998
Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs.Critical care medicine, , Volume: 25, Issue:7, 1997
Acute lung injury in endotoxemic pigs: role of leukotriene B4.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 78, Issue:3, 1995
Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs.The American journal of physiology, , Volume: 269, Issue:6 Pt 2, 1995
[Preoperative low energy laser irradiation of the lungs and its effect on prostaglandin and cyclic nucleotide metabolism].Problemy tuberkuleza, , Issue:4, 1994
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Structural and biochemical changes in lungs of 3-methylindole-treated rats.The American journal of pathology, , Volume: 142, Issue:1, 1993
Effect of a 5-lipoxygenase inhibitor on endotoxin-induced pulmonary dysfunction in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:2, 1993
Aspirin effect on early and late changes in acute lung injury in sheep.Intensive care medicine, , Volume: 19, Issue:1, 1993
CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs.The American journal of physiology, , Volume: 264, Issue:4 Pt 2, 1993
Enhanced microvascular permeability of PMA-induced acute lung injury is not mediated by cyclooxygenase products.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:5, 1992
Effects of thromboxane synthase inhibition on tumor necrosis factor-induced lung injury in sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:2, 1992
Vascular resistance and Kf in normal and PMA-injured rabbit lungs: effects of adenosine.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 71, Issue:2, 1991
[Plasma PGI2 and TXA2 levels on a model of PDH in leptospirosis].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 22, Issue:3, 1991
[The observation of changes in plasma PGI2 and TXA2 levels and the therapeutic effect of tetramethylpyrazine in E. coli induced acute lung injury in rabbits].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 14, Issue:3, 1991
Pulmonary hypertensive response to foreign body microemboli.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:2, 1990
Effect of 3-methylindole on the plasma and lung concentrations of prostaglandins and thromboxane B2 in goats.Comparative biochemistry and physiology. A, Comparative physiology, , Volume: 94, Issue:4, 1989
Corticosteroids prevent acute lung dysfunction caused by thoracic irradiation in unanesthetized sheep.The American review of respiratory disease, , Volume: 138, Issue:5, 1988
The role of cyclooxygenase and lipoxygenase mediators in oxidant-induced lung injury.The American review of respiratory disease, , Volume: 137, Issue:6, 1988
Acute cigarette smoke exposure causes lung injury in rabbits treated with ibuprofen.Experimental lung research, , Volume: 13, Issue:2, 1987
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Lung permeability and hemodynamics during endotoxemia: effect of aprotinin.The Journal of surgical research, , Volume: 41, Issue:6, 1986
Acute effect of paraquat on lung fluid balance and prostanoid production in awake sheep.The American review of respiratory disease, , Volume: 134, Issue:6, 1986
The early involvement of pulmonary prostaglandins in hyperoxic lung injury.Prostaglandins, leukotrienes, and medicine, , Volume: 25, Issue:2-3, 1986
Hyperoxic lung injury in mice: a possible protective role for prostacyclin.The Journal of laboratory and clinical medicine, , Volume: 108, Issue:5, 1986
Studies on the role of thromboxane in thrombin-induced pulmonary insufficiency in the rat.Thrombosis research, , Apr-15, Volume: 42, Issue:2, 1986
Thromboxane as a mediator of pulmonary dysfunction during intravascular complement activation in sheep.The American review of respiratory disease, , Volume: 133, Issue:2, 1986
Prostaglandins and estradiol-induced attenuation of hypoxic pulmonary vasoconstriction.Chest, , Volume: 88, Issue:4 Suppl, 1985
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[The role of PGI2 and TXA2 in the pathogenesis of endotoxin-induced lung injury].Masui. The Japanese journal of anesthesiology, , Volume: 34, Issue:12, 1985
Mechanisms of interaction between oxygen and granulocytes in hyperoxic lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 58, Issue:4, 1985
Prostaglandins and thromboxanes in the bronchoalveolar lavage fluid: possible immunoregulation in sarcoidosis.The American review of respiratory disease, , Volume: 130, Issue:5, 1984
Prostaglandin release and altered microvascular integrity after burn injury.The Journal of surgical research, , Volume: 31, Issue:4, 1981
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Specific neutrophil elastase inhibitor does not attenuate acute lung injury induced by air embolism in awake sheep.Experimental lung research, , Volume: 22, Issue:6
Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin.American journal of medical genetics. Part A, , Volume: 152A, Issue:8, 2010
Thromboxane and prostacyclin metabolites in pulmonary hypertension.The New England journal of medicine, , Nov-12, Volume: 327, Issue:20, 1992
[The interaction of some active and immunological factors in blood in the development of chronic cor pulmonale].Zhonghua nei ke za zhi, , Volume: 31, Issue:3, 1992
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.The New England journal of medicine, , Jul-09, Volume: 327, Issue:2, 1992
[Changes of thromboxane A2 (TXA2) and prostacyclin (PGI2) in COPD patients with pulmonary hypertension].Zhonghua nei ke za zhi, , Volume: 30, Issue:2, 1991
Platelet activity in relation to smoke and exercise in patients with chronic obstructive lung disease: effects of platelet antiaggregating drugs.Advances in experimental medicine and biology, , Volume: 164, 1984
Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2.Carcinogenesis, , Volume: 25, Issue:8, 2004
Prostacyclin in human non-small cell lung cancers.Chest, , Volume: 125, Issue:5 Suppl, 2004
The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice.Toxicology, , Dec-01, Volume: 169, Issue:1, 2001
[Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 17, Issue:9, 1997
[Study on advanced non-small cell lung cancer patients with Qi deficiency and blood stasis syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 14, Issue:12, 1994
[Antimetastatic action of polyactin A and its mechanism].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 29, Issue:5, 1994
Sensitivity of tumoricidal function in macrophages from different anatomical sites of cancer patients to modulation of arachidonic acid metabolism.Cancer research, , Jul-15, Volume: 53, Issue:14, 1993
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Plasma prostaglandins in lung cancer.European journal of cancer & clinical oncology, , Volume: 24, Issue:6, 1988
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[Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation].Kyobu geka. The Japanese journal of thoracic surgery, , Volume: 37, Issue:10, 1984
Inhibition of tumor cell metastasis by modulation of the vascular prostacyclin/thromboxane A2 system.Clinical & experimental metastasis, , Volume: 1, Issue:2
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Effect of antibodies to double stranded DNA, purified from serum samples of patients with active systemic lupus erythematosus, on the glomerular mesangial cells.Annals of the rheumatic diseases, , Volume: 51, Issue:2, 1992
Haemostatic factors associated with vascular thrombosis in patients with systemic lupus erythematosus and the lupus anticoagulant.Annals of the rheumatic diseases, , Volume: 50, Issue:8, 1991
Effects of the lupus anticoagulant in patients with systemic lupus erythematosus on endothelial cell prostacyclin release and procoagulant activity.The Journal of investigative dermatology, , Volume: 90, Issue:5, 1988
Prostacyclin in systemic lupus and anticardiolipin syndrome.Annals of the rheumatic diseases, , Volume: 46, Issue:5, 1987
Essential fatty acids in diabetes and systemic lupus erythematosus (SLE) patients.Biochemical and biophysical research communications, , Apr-30, Volume: 128, Issue:2, 1985
Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis.Kidney international, , Volume: 60, Issue:2, 2001
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The functional and structural changes of the glomerulus throughout the course of murine lupus nephritis.Journal of the American Society of Nephrology : JASN, , Volume: 3, Issue:4, 1992
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An imbalance between the excretion of thromboxane and prostacyclin metabolites in women after the menopause.Zentralblatt fur Gynakologie, , Volume: 115, Issue:4, 1993
Female sex hormones and platelet/endothelial cell interactions.Haemostasis, , Volume: 20, Issue:6, 1990
Prostanoids and catecholamines after oral administration of natural progesterone.Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, , Volume: 3, Issue:2, 1989
Decreased in vitro production of 6-keto-prostaglandin F1 alpha by uterine arteries from postmenopausal women.American journal of obstetrics and gynecology, , Volume: 161, Issue:6 Pt 1, 1989
Effect of ovariectomy in humans on serum 6-keto-PGF1 alpha and TXB2 concentrations and platelet fatty acids.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:1, 1987
Dermal prostacyclin, thromboxane A2 and prostaglandin F2 alpha in climacteric women: effect of oestrogen replacement therapy.Maturitas, , Volume: 8, Issue:1, 1986
Effect of HDL and LDL from pre and post menopausal women on prostacyclin synthesis.Prostaglandins, , Volume: 30, Issue:2, 1985
The concentrations of 6-keto-PGF1 alpha and TXB2 in plasma samples from patients with benign and malignant tumours of the breast.Prostaglandins, , Volume: 29, Issue:4, 1985
Suppression of plasma 6-keto-prostaglandin F1 alpha and 13,14-dihydro-15-keto-prostaglandin F2 alpha by aminoglutethimide in advanced breast cancer.British journal of cancer, , Volume: 48, Issue:4, 1983
Prostacyclin from the uterus and woman's cardiovascular advantage.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:5, 1982
[Intrauterine device-induced menorrhagia and endometrial content of prostacyclins].Zhonghua fu chan ke za zhi, , Volume: 27, Issue:3, 1992
Studies on IUD-induced menorrhagia and increased synthesis of prostacyclin in endometrium.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 8, Issue:4, 1988
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
A role for prostacyclin (PGi2) in excessive menstrual bleeding.Lancet (London, England), , Mar-07, Volume: 1, Issue:8219, 1981
Naproxen sodium in short-term prophylaxis of pure menstrual migraine: pathophysiological and clinical considerations.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, , Volume: 28 Suppl 2, 2007
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Relevance of prostaglandins in true menstrual migraine.Headache, , Volume: 29, Issue:4, 1989
Platelet function in classic migraine during attack-free periods.Acta neurologica Scandinavica, , Volume: 78, Issue:4, 1988
[Role of blood platelet aggregation in menstrual migraine].Minerva medica, , Jul-31, Volume: 78, Issue:14, 1987
Beta-adrenoceptor blockade, platelets, and rheologic factors.Cephalalgia : an international journal of headache, , Volume: 6 Suppl 5, 1986
Thromboxane synthetase inhibition: potential therapy in migraine.Headache, , Volume: 25, Issue:4, 1985
Salicylate treatment in Kawasaki disease: high dose or low dose?European journal of pediatrics, , Volume: 150, Issue:9, 1991
[Plasma PGE2, TXB2 and 6-keto PGF1 alpha levels in patients with Kawasaki disease].Arerugi = [Allergy], , Volume: 37, Issue:9, 1988
Effects of current therapy of Kawasaki disease on eicosanoid metabolism.The American journal of cardiology, , Jun-01, Volume: 61, Issue:15, 1988
Antithrombin ameliorates endotoxin-induced organ dysfunction more efficiently when combined with danaparoid sodium than with unfractionated heparin.Intensive care medicine, , Volume: 31, Issue:8, 2005
Are lipid mediators implicated in the production of pro- and anti-inflammatory cytokines during cardiopulmonary bypass graft with extracorporeal circulation?Cytokine, , Volume: 11, Issue:4, 1999
Effects of inhibitors of the activity of cyclo-oxygenase-2 on the hypotension and multiple organ dysfunction caused by endotoxin: a comparison with dexamethasone.British journal of pharmacology, , Volume: 124, Issue:3, 1998
Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns.Burns : journal of the International Society for Burn Injuries, , Volume: 24, Issue:8, 1998
Effect of calpain inhibitor I, an inhibitor of the proteolysis of I kappa B, on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat.British journal of pharmacology, , Volume: 121, Issue:4, 1997
[Thromboxane and prostacyclin imbalance in the pathogenesis of early damage after severe burns].Zhonghua yi xue za zhi, , Volume: 73, Issue:10, 1993
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
[Clinical study on main visceral damage and multiple organ failure (MOF) following severe burns].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 9, Issue:3, 1993
A prospective clinical study on the pathogenesis of multiple organ failure in severely burned patients.Burns : journal of the International Society for Burn Injuries, , Volume: 18, Issue:1, 1992
[Changes in plasma prostaglandin F2, thromboxane B2 and 6-keto-prostaglandin F1 alpha contents in patients suffering from multiple system organ failure after burns].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 8, Issue:1, 1992
[Clinical study of the pathogeneses of multiple organ failure after burns].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 8, Issue:1, 1992
Imbalance between plasma levels of thromboxane B2 and 6-keto-prostaglandin F1 alpha during subacute endotoxin-induced hyperdynamic sepsis or multiple organ failure syndrome in sheep.Circulatory shock, , Volume: 35, Issue:2, 1991
An increase in the ratio of thromboxane A2 to prostacyclin in association with increased blood pressure in patients on cyclosporine A.Prostaglandins, , Volume: 37, Issue:5, 1989
A study of the prostaglandin and thromboxane content of the central nervous tissues with the development of chronic relapsing allergic encephalomyelitis.Journal of neuroimmunology, , Volume: 10, Issue:3, 1986
[Prostaglandins in the cerebrospinal fluid of patients with multiple sclerosis].Neurologija, , Volume: 34, Issue:1-4, 1985
Chronic restraint stress increases angiotensin II potency in the rat carotid: role of cyclooxygenases and reactive oxygen species.The Journal of pharmacy and pharmacology, , Volume: 69, Issue:1, 2017
Healthy older humans exhibit augmented carotid-cardiac baroreflex sensitivity with aspirin during muscle mechanoreflex and metaboreflex activation.American journal of physiology. Heart and circulatory physiology, , Volume: 309, Issue:8, 2015
Effect of extraluminal ATP application on vascular tone and blood flow in skeletal muscle: implications for exercise hyperemia.American journal of physiology. Regulatory, integrative and comparative physiology, , Aug-01, Volume: 305, Issue:3, 2013
Modulation of airway responses by prostaglandins in young and fully grown rabbits.American journal of physiology. Lung cellular and molecular physiology, , Volume: 293, Issue:1, 2007
Involvement of calcium/calmodulin-dependent protein kinase II to endotoxin-induced vascular hyporeactivity in rat superior mesenteric artery.Pharmacological research, , Volume: 54, Issue:3, 2006
Celecoxib inhibits ureteral contractility and prostanoid release.Urology, , Volume: 65, Issue:1, 2005
Differential effects of 5,6-EET on segmental pulmonary vasoactivity in the rabbit.American journal of physiology. Heart and circulatory physiology, , Volume: 284, Issue:6, 2003
Mechanisms underlying increased release of endothelin-1 from aorta in diabetic rats.Peptides, , Volume: 22, Issue:4, 2001
Bradykinin and electrical stimulation increase prostaglandin production in the rat vas deferens.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 65, Issue:1, 2001
Serotonin hypersensitivity in aorta of two kidney-two clip hypertensive rats: calcium contribution and prostanoids-nitric oxide interactions.Archives of physiology and biochemistry, , Volume: 109, Issue:1, 2001
In utero remodeling of the fetal lamb ductus arteriosus: the role of antenatal indomethacin and avascular zone thickness on vasa vasorum proliferation, neointima formation, and cell death.Circulation, , Apr-03, Volume: 103, Issue:13, 2001
Defibrotide normalizes cardiovascular function hampered by established atherosclerosis in the rabbit.Thrombosis research, , Jan-15, Volume: 97, Issue:2, 2000
The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation.British journal of pharmacology, , Volume: 126, Issue:1, 1999
Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 60, Issue:4, 1999
Thrombin receptor expression is increased by angiotensin II in cultured and native vascular smooth muscle cells.Cardiovascular research, , Volume: 38, Issue:1, 1998
Methacholine-induced contraction of rabbit pulmonary artery: role of platelet-endothelial transcellular thromboxane synthesis.Hypertension (Dallas, Tex. : 1979), , Volume: 31, Issue:1 Pt 2, 1998
Endothelium-derived hyperpolarizing factor, but not nitric oxide, is reversibly inhibited by brefeldin A.Hypertension (Dallas, Tex. : 1979), , Volume: 30, Issue:6, 1997
Chronic inhibition of NO synthase enhances the production of prostacyclin in coronary arteries through upregulation of the cyclooxygenase type 1 isoform.Fundamental & clinical pharmacology, , Volume: 11, Issue:3, 1997
Alteration of flow-induced dilatation in mesenteric resistance arteries of L-NAME treated rats and its partial association with induction of cyclo-oxygenase-2.British journal of pharmacology, , Volume: 121, Issue:1, 1997
Effect of acetylsalicylic acid on metabolism and contractility in the ischemic reperfused heart.Japanese circulation journal, , Volume: 60, Issue:12, 1996
Interactions between nitric oxide and prostanoids in isolated perfused kidneys of the rat.British journal of pharmacology, , Volume: 119, Issue:2, 1996
Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae.The American journal of physiology, , Volume: 267, Issue:6 Pt 2, 1994
Vascular mode of action of kinin B1 receptors and development of a cellular model for the investigation of these receptors.British journal of pharmacology, , Volume: 109, Issue:4, 1993
Leukotriene D4 receptors are not negatively coupled to adenylyl cyclase in guinea-pig lung parenchyma.British journal of pharmacology, , Volume: 108, Issue:3, 1993
Correlation with blood pressure of the acetylcholine-induced endothelium-derived contracting factor in the rat aorta.Hypertension (Dallas, Tex. : 1979), , Volume: 19, Issue:4, 1992
Bovine polymorphonuclear leukocytes increase sensitivity to noradrenaline in isolated mesenteric arteries.British journal of pharmacology, , Volume: 105, Issue:3, 1992
[Effects of arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid on tension of rabbit aortic strips].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 27, Issue:4, 1992
Intramuscular accumulation of prostaglandins during static contraction of the cat triceps surae.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 71, Issue:5, 1991
Effect of platelet-activating factor on porcine pulmonary blood vessels in vitro.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 344, Issue:4, 1991
Comparison of responses to angiotensin II of dog mesenteric arteries and veins.European journal of pharmacology, , Aug-29, Volume: 201, Issue:2-3, 1991
Method of removal of aortic endothelium affects arachidonic acid metabolism and vascular reactivity.European journal of pharmacology, , Feb-14, Volume: 193, Issue:3, 1991
The effect of euthanasia technique on vascular arachidonic acid metabolism and vascular and intestinal smooth muscle contractility.Laboratory animal science, , Volume: 40, Issue:3, 1990
Removal of guinea pig bronchial and tracheal epithelium potentiates the contractions to leukotrienes and histamine.Eicosanoids, , Volume: 3, Issue:1, 1990
Epithelium-derived PGE2 inhibits the contractile response to cholinergic stimulation in isolated ferret trachea.Pulmonary pharmacology, , Volume: 3, Issue:3, 1990
Defibrotide, by enhancing prostacyclin generation, prevents endothelin-1 induced contraction in human saphenous veins.Prostaglandins, , Volume: 40, Issue:4, 1990
[Effect of products released by activated neutrophils on pulmonary arterial pressure].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 13, Issue:5, 1990
[The role of the endothelium in the beta-adrenergic regulation of vascular tonus].Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, , Volume: 75, Issue:6, 1989
Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta.Prostaglandins, leukotrienes, and medicine, , Volume: 30, Issue:1, 1987
The effect of prostaglandin synthesis inhibition on motility of the sheep ureter.Acta physiologica Scandinavica, , Volume: 131, Issue:1, 1987
Physiological concentrations of epinephrine potentiate thromboxane A2 release from platelets in the isolated rat heart.Circulation research, , Volume: 58, Issue:1, 1986
Flow-induced release of endothelium-derived relaxing factor.The American journal of physiology, , Volume: 250, Issue:6 Pt 2, 1986
Biological profile of a bioactive aortic substance (BAS), released by vessel rings from indomethacin-treated rats.Prostaglandins, leukotrienes, and medicine, , Volume: 22, Issue:2, 1986
Effects of prostaglandin I2 synthesized in the endothelium and in the smooth muscle on mechanical properties of the canine thoracic aorta.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 333, Issue:3, 1986
Compartmental prostaglandin release by angiotensin II and arginine-vasopressin in rabbit isolated perfused kidneys.European journal of pharmacology, , Jan-14, Volume: 120, Issue:1, 1986
Feedback control of arterial smooth muscle tone: the role of prostacyclin.British journal of pharmacology, , Volume: 89, Issue:4, 1986
Effects of a thromboxane synthetase inhibitor and a thromboxane antagonist on release and activity of thromboxane A2 and prostacyclin in vitro.Prostaglandins, , Volume: 29, Issue:5, 1985
Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.The American journal of physiology, , Volume: 248, Issue:6 Pt 2, 1985
Endogenous prostaglandins modulate histamine-induced contraction in canine tracheal smooth muscle.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 58, Issue:3, 1985
Adrenergic stimulation of prostacyclin production in the rat tail artery. I. Response to agonists and antagonists.Prostaglandins, leukotrienes, and medicine, , Volume: 20, Issue:3, 1985
Prostacyclin, its fatty acid precursor and its metabolites on the inotropic function of and on the prostanoid generation by diabetic arteries.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
Leukotriene-induced contraction and thromboxane production in guinea-pig lung parenchymal strips.European journal of pharmacology, , Jul-13, Volume: 102, Issue:2, 1984
Norepinephrine-stimulated vascular prostacyclin synthesis. Receptor-dependent calcium channels control prostaglandin synthesis.Canadian journal of physiology and pharmacology, , Volume: 62, Issue:11, 1984
Mechanical trauma to bladder epithelium liberates prostanoids which modulate neurotransmission in rabbit detrusor muscle.The Journal of pharmacology and experimental therapeutics, , Volume: 230, Issue:2, 1984
Release of slow reacting substance from the guinea-pig lung by phospholipases A2 of Vipera russelli snake venom.Toxicon : official journal of the International Society on Toxinology, , Volume: 22, Issue:3, 1984
Release of slow-reacting substance of anaphylaxis and leukotriene C4-like immunoreactivity from guinea pig colonic tissue.Prostaglandins, , Volume: 25, Issue:6, 1983
Angiotensin II: a releaser of PGI2 from fetal and newborn rabbit lungs.Prostaglandins, , Volume: 25, Issue:6, 1983
Prostaglandin synthesis by, and the effects of prostaglandins and prostaglandin analogues on, the vas deferens of the rabbit and rat in vitro.Journal of reproduction and fertility, , Volume: 69, Issue:1, 1983
Responses of isolated feline and human cerebral arteries to prostacyclin and some of its metabolites.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 3, Issue:2, 1983
Renal metabolism of sulindac, a novel nonsteroidal antiinflammatory agent.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Effects of prostaglandin(PG) E2, D2, I2, 6-keto-PGF1 alpha and arachidonic acid on excitatory transmission of canine small intestine.Journal of autonomic pharmacology, , Volume: 2, Issue:4, 1982
Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2.Prostaglandins and medicine, , Volume: 6, Issue:3, 1981
Effects of prostacyclin on rat seminal vesicle contractility in vitro.Endocrine research communications, , Volume: 8, Issue:1, 1981
Effects of prostacyclin (PGI2) on the smooth muscles of the guinea-pig stomach.Archives internationales de pharmacodynamie et de therapie, , Volume: 253, Issue:1, 1981
Comparative effects of leukotriene B4, prostaglandins I2 and E2, 6-keto-PGF1 alpha thromboxane B2 and histamine on selected smooth muscle preparations.The Journal of pharmacy and pharmacology, , Volume: 33, Issue:7, 1981
Human plasma transforms prostacyclin (PGI2) into a platelet antiaggregatory substance which contracts isolated bovine coronary arteries.Prostaglandins, , Volume: 19, Issue:6, 1980
Comparison of the effect of continuous intravenous infusion of prostaglandins E1, E2, I, or 6-keto-PGF1 alpha on lower esophageal sphincter pressure.Advances in prostaglandin and thromboxane research, , Volume: 8, 1980
Inhibition of nitric oxide synthesis by systemic N(G)-monomethyl-L-arginine administration in humans: effects on interstitial adenosine, prostacyclin and potassium concentrations in resting and contracting skeletal muscle.Journal of vascular research, , Volume: 37, Issue:4
Altered aortic production of 6-keto-prostaglandin F1 alpha from aldosterone-salt hypertensive rats.Journal of vascular research, , Volume: 29, Issue:3
Pharmacological characterization of the relaxant effect induced by adrenomedullin in rat cavernosal smooth muscle.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, , Volume: 47, Issue:10, 2014
Chronic inhibition of nitric-oxide synthase potentiates endothelium-dependent contractions in the rat aorta by augmenting the expression of cyclooxygenase-2.The Journal of pharmacology and experimental therapeutics, , Volume: 334, Issue:2, 2010
VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 297, Issue:4, 2009
Modulation of airway responses by prostaglandins in young and fully grown rabbits.American journal of physiology. Lung cellular and molecular physiology, , Volume: 293, Issue:1, 2007
Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection.Life sciences, , Oct-17, Volume: 73, Issue:22, 2003
Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 362, Issue:1, 2000
The cyclo-oxygenase-dependent regulation of rabbit vein contraction: evidence for a prostaglandin E2-mediated relaxation.British journal of pharmacology, , Volume: 126, Issue:1, 1999
Chronic inhibition of NO synthase enhances the production of prostacyclin in coronary arteries through upregulation of the cyclooxygenase type 1 isoform.Fundamental & clinical pharmacology, , Volume: 11, Issue:3, 1997
RU 38486 inhibits intracellular calcium mobilization and PGI2 release from human myometrium: mechanisms of action.The Journal of steroid biochemistry and molecular biology, , Volume: 59, Issue:1, 1996
Gender difference in bioassayable endothelium-derived nitric oxide from isolated rat aortae.The American journal of physiology, , Volume: 267, Issue:6 Pt 2, 1994
NG-monomethyl-L-arginine paradoxically relaxes preconstricted canine intrapulmonary arteries.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:2, 1993
Activation of an epithelial neurokinin NK-1 receptor induces relaxation of rat trachea through release of prostaglandin E2.The Journal of pharmacology and experimental therapeutics, , Volume: 263, Issue:2, 1992
Correlation with blood pressure of the acetylcholine-induced endothelium-derived contracting factor in the rat aorta.Hypertension (Dallas, Tex. : 1979), , Volume: 19, Issue:4, 1992
Blood pressure and vascular reactivity changes in spontaneously hypertensive rats fed fish oil.British journal of pharmacology, , Volume: 102, Issue:4, 1991
Comparison of responses to angiotensin II of dog mesenteric arteries and veins.European journal of pharmacology, , Aug-29, Volume: 201, Issue:2-3, 1991
Ciclosporin A inhibits endothelium-dependent vasodilatation and vascular prostacyclin production.European journal of pharmacology, , Jun-08, Volume: 165, Issue:1, 1989
Effect of pure eicosapentaenoic acid feeding on blood pressure and vascular reactivity in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 15, Issue:4, 1988
Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta.Prostaglandins, leukotrienes, and medicine, , Volume: 30, Issue:1, 1987
Effects of low molecular weight fibrin degradation products 6A and 6D on rabbit aorta strips.Agents and actions, , Volume: 22, Issue:1-2, 1987
Flow-induced release of endothelium-derived relaxing factor.The American journal of physiology, , Volume: 250, Issue:6 Pt 2, 1986
Effects of the C5a anaphylatoxin and its relationship to cyclo-oxygenase metabolites in rabbit vascular strips.British journal of pharmacology, , Volume: 84, Issue:3, 1985
Generation of arachidonic acid metabolites from stimulated whole blood in patients with chronic myeloproliferative disorders.Acta haematologica, , Volume: 85, Issue:2, 1991
Platelet function studies in myeloproliferative disorders.Folia haematologica (Leipzig, Germany : 1928), , Volume: 113, Issue:5, 1986
Normal vascular prostacyclin generation in patients with chronic myeloproliferative disorders.Thrombosis research, , Jul-01, Volume: 39, Issue:1, 1985
Panax quinquefolius saponins combined with dual antiplatelet drug therapy alleviate gastric mucosal injury and thrombogenesis through the COX/PG pathway in a rat model of acute myocardial infarction.PloS one, , Volume: 13, Issue:3, 2018
Microvascular pathological features and changes in related injury factors in a rat acute blood stasis model.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 37, Issue:1, 2017
Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect.Arteriosclerosis, thrombosis, and vascular biology, , Volume: 34, Issue:9, 2014
Association of cyclooxygenase-2 genetic variant with cardiovascular disease.European heart journal, , Sep-01, Volume: 35, Issue:33, 2014
Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat.Journal of cardiovascular pharmacology and therapeutics, , Volume: 13, Issue:1, 2008
The role of eNOS, iNOS, and NF-kappaB in upregulation and activation of cyclooxygenase-2 and infarct size reduction by atorvastatin.American journal of physiology. Heart and circulatory physiology, , Volume: 295, Issue:1, 2008
[Association of polymorphism of the prostacyclin synthase gene with myocardial infarction in Uigur population of Xinjiang].Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, , Volume: 25, Issue:6, 2008
Pioglitazone protects the myocardium against ischemia-reperfusion injury in eNOS and iNOS knockout mice.American journal of physiology. Heart and circulatory physiology, , Volume: 295, Issue:6, 2008
Aspirin before reperfusion blunts the infarct size limiting effect of atorvastatin.American journal of physiology. Heart and circulatory physiology, , Volume: 292, Issue:6, 2007
[Study on comparative pharmacology of series of Muskone].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 31, Issue:16, 2006
[Study on therapeutic effects of series of muskone on myocardial infarction canines].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 31, Issue:20, 2006
COX-2 mediates morphine-induced delayed cardioprotection via an iNOS-dependent mechanism.Life sciences, , Apr-25, Volume: 78, Issue:22, 2006
Cyclooxygenase-1 mediates the final stage of morphine-induced delayed cardioprotection in concert with cyclooxygenase-2.Journal of the American College of Cardiology, , May-17, Volume: 45, Issue:10, 2005
Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo.Anesthesiology, , Volume: 100, Issue:3, 2004
Delta-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits.American journal of physiology. Heart and circulatory physiology, , Volume: 283, Issue:5, 2002
Transcardiac 8-iso-prostaglandin F(2 alpha)generation from acute myocardial infarction heart: insight into abrupt reperfusion and oxidant stress.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 64, Issue:3, 2001
Effect of cyclooxygenase-2 inhibitor (celecoxib) on the infarcted heart in situ.Pharmacology, , Volume: 63, Issue:1, 2001
The effect of aspirin and two nitric oxide donors on the infarcted heart in situ.Life sciences, , Jul-07, Volume: 67, Issue:7, 2000
The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation.Stroke, , Volume: 31, Issue:6, 2000
[Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension].Terapevticheskii arkhiv, , Volume: 72, Issue:4, 2000
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Dietary soy protein reduces early renal disease progression and alters prostanoid production in obese fa/fa Zucker rats.The Journal of nutritional biochemistry, , Volume: 19, Issue:4, 2008
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Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 71, Issue:5, 2004
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.International journal of gastrointestinal cancer, , Volume: 32, Issue:1, 2002
[Measurement of prostaglandins in human bile juice].Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, , Volume: 81, Issue:9, 1984
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Effects of long-acting somatostatin analog (SMS 201-995) on eicosanoid synthesis and survival in rats with acute necrotizing pancreatitis.Digestive diseases and sciences, , Volume: 37, Issue:9, 1992
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Platelet function in experimentally induced pancreatitis in the dog.Thrombosis and haemostasis, , Apr-30, Volume: 55, Issue:2, 1986
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A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.Journal of pharmacological sciences, , Volume: 130, Issue:2, 2016
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Salivary isoprostanes indicate increased oxidation injury in periodontitis with additional tobacco abuse.BioFactors (Oxford, England), , Volume: 28, Issue:1, 2006
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A comparison of the anti-inflammatory activity of selective 5-lipoxygenase inhibitors with dexamethasone and colchicine in a model of zymosan induced inflammation in the rat knee joint and peritoneal cavity.Agents and actions, , Volume: 32, Issue:3-4, 1991
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Early biochemical events in pneumococcal otitis media: arachidonic acid metabolites in middle ear fluid.The Annals of otology, rhinology, and laryngology, , Volume: 100, Issue:5 Pt 1, 1991
Protective effect of beraprost sodium, a stable prostacyclin analog, in the development of cigarette smoke extract-induced emphysema.American journal of physiology. Lung cellular and molecular physiology, , Volume: 296, Issue:4, 2009
The lung tumor promoter, butylated hydroxytoluene (BHT), causes chronic inflammation in promotion-sensitive BALB/cByJ mice but not in promotion-resistant CXB4 mice.Toxicology, , Dec-01, Volume: 169, Issue:1, 2001
Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia.The American review of respiratory disease, , Volume: 142, Issue:1, 1990
Systemic lipid peroxidation and inflammation induced by thermal injury persists into the post-resuscitation period.The Journal of trauma, , Volume: 30, Issue:1, 1990
Effect of cyclooxygenase blockade on gas exchange and hemodynamics in Pseudomonas pneumonia.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 63, Issue:5, 1987
Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.The American journal of physiology, , Volume: 248, Issue:6 Pt 2, 1985
Ibuprofen modifies the inflammatory response of the murine lung to Pseudomonas aeruginosa.European journal of respiratory diseases, , Volume: 67, Issue:2, 1985
Colon-specific delivery of celecoxib is a potential strategy to improve toxicological and pharmacological properties of the selective Cox-2 inhibitor: implication in treatment of familiar adenomatous polyposis.Journal of drug targeting, , Volume: 20, Issue:6, 2012
Discordant effect of aspirin and indomethacin on intestinal tumor burden in Apc(Min/+)mice.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:5, 2000
Size-dependent increase in prostanoid levels in adenomas of patients with familial adenomatous polyposis.Cancer research, , Apr-15, Volume: 58, Issue:8, 1998
Renal synthesis of prostacyclin and thromboxane in healthy women: differential effects of a short-term saline loading.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:2, 2000
Amelioration of polyuria in nephrogenic diabetes insipidus due to aquaporin-2 deficiency.Clinical endocrinology, , Volume: 49, Issue:1, 1998
Interactions between the renin-angiotensin system and prostanoids in modulating renal function in potassium-depleted healthy women.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 50, Issue:6, 1994
Urinary prostanoid excretion in healthy women with different degrees of induced potassium depletion.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 46, Issue:1, 1992
[Renal function in experimental potassium depletion. I. Effects of lysine-8-vasopressin in hypotonic polyuria].Bollettino della Societa italiana di biologia sperimentale, , Volume: 65, Issue:12, 1989
[Renal function in experimental potassium depletion. II. Indomethacin and effects of lysine-8-vasopressin in hypotonic polyuria].Bollettino della Societa italiana di biologia sperimentale, , Volume: 65, Issue:12, 1989
[Potassium balance, acute alterations in diuresis and urinary excretion of arachidonic acid metabolites. III: Relation between functional parameters].Bollettino della Societa italiana di biologia sperimentale, , Jul-30, Volume: 61, Issue:7, 1985
Laser speckle contrast imaging for quantitative assessment of facial flushing during mesenteric traction syndrome in upper gastrointestinal surgery.Journal of clinical monitoring and computing, , Volume: 33, Issue:5, 2019
The urinary levels of prostanoid metabolites predict acute kidney injury in heterogeneous adult Japanese ICU patients: a prospective observational study.Clinical and experimental nephrology, , Volume: 19, Issue:6, 2015
Flurbiprofen axetil provides a prophylactic benefit against mesenteric traction syndrome associated with remifentanil infusion during laparotomy.Journal of anesthesia, , Volume: 26, Issue:4, 2012
Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up.Journal of the neurological sciences, , Dec-15, Volume: 287, Issue:1-2, 2009
Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage.Chinese medical journal, , Dec-05, Volume: 120, Issue:23, 2007
The effect of a selective cyclooxygenase-2 inhibitor in extended liver resection with ischemia in dogs.The Journal of surgical research, , Volume: 100, Issue:1, 2001
Leukocyte and platelet depletion with a blood cell separator: effects on lung injury after cardiac surgery with cardiopulmonary bypass.The Journal of thoracic and cardiovascular surgery, , Volume: 111, Issue:1, 1996
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
Prevention of postoperative pericardial adhesions by closure of the pericardium with absorbable polymer patches. An experimental study.The Journal of thoracic and cardiovascular surgery, , Volume: 104, Issue:3, 1992
Effects of CGS-13080, a thromboxane inhibitor, on pulmonary vascular resistance in patients after mitral valve replacement surgery.Circulation, , Volume: 78, Issue:3 Pt 2, 1988
Blood conservation with membrane oxygenators and dipyridamole.The Annals of thoracic surgery, , Volume: 44, Issue:1, 1987
Thromboxane and prostacyclin release in adult respiratory distress syndrome.Intensive care medicine, , Volume: 13, Issue:3, 1987
Thromboxane release during percutaneous transluminal coronary angioplasty.American heart journal, , Volume: 111, Issue:1, 1986
Chronic rejection in rat aortic allografts. IV. Effect of hypercholesterolemia in allograft arteriosclerosis.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , Volume: 12, Issue:1 Pt 1
Laser endarterectomy: a comparison of thrombotic potential following CO2 laser vs surgical endarterectomy.Stroke, , Volume: 17, Issue:2
Urinary excretion of prostaglandins and renal function after hepatic resection.Hepato-gastroenterology, , Volume: 44, Issue:15
Effect of hypertonic sodium chloride hydroxyethyl starch 40 on ET, TXB2, 6-keto-PGF1α, and ANP of preeclampsia in caesarean section.Clinical and experimental obstetrics & gynecology, , Volume: 42, Issue:1, 2015
The biological investigation of prostacyclin in preeclamptic women seen reduced endothelial function.Hypertension in pregnancy, , Volume: 29, Issue:4, 2010
Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies.Placenta, , Volume: 29, Issue:1, 2008
Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia condition.Placenta, , Volume: 26, Issue:5, 2005
Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia.American journal of obstetrics and gynecology, , Volume: 188, Issue:4, 2003
Normalization of vasoactive changes in preeclampsia precedes clinical recovery.Hypertension in pregnancy, , Volume: 21, Issue:1, 2002
Vasoactive mediator release by fetal endothelial cells in intrauterine growth restriction and preeclampsia.American journal of obstetrics and gynecology, , Volume: 184, Issue:3, 2001
Production of vasoactive substances by human umbilical vein endothelial cells after incubation with serum from preeclamptic patients.European journal of obstetrics, gynecology, and reproductive biology, , Dec-01, Volume: 99, Issue:2, 2001
Prostacyclin deficiency and reduced fetoplacental blood flow in pregnancy-induced hypertension and preeclampsia.Gynecologic and obstetric investigation, , Volume: 50, Issue:2, 2000
Maternal thromboxane and prostacyclin levels in relation to fetal birth weight.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 93, Issue:1, 2000
[The effect of plasma from women with preeclampsia on endothelial cells activators in vitro].Zhonghua fu chan ke za zhi, , Volume: 35, Issue:7, 2000
Interleukin-8 stimulates placental prostacyclin production in preeclampsia.American journal of reproductive immunology (New York, N.Y. : 1989), , Volume: 42, Issue:6, 1999
[Study on tumor necrosis factor and pathogenesis of pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 34, Issue:6, 1999
[The effect of inhibition of nitric oxide synthesis on vasoregulatory factors in pregnant rats].Zhonghua fu chan ke za zhi, , Volume: 34, Issue:9, 1999
Effects of lipoproteins from pre-eclamptic women on umbilical endothelial cell 6-oxo-prostaglandin f1alpha and endothelin 1 synthesis, and nitric oxide synthase 3 mRNA expression.Clinical science (London, England : 1979), , Volume: 97, Issue:6, 1999
Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia?Journal of hypertension, , Volume: 17, Issue:9, 1999
An imbalance between prostacyclin and thromboxane in relation to cerebral blood flow in neonates with maternal preeclampsia.Prostaglandins & other lipid mediators, , Volume: 58, Issue:1, 1999
Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study.JAMA, , Jul-28, Volume: 282, Issue:4, 1999
Effects of magnesium sulfate infusion upon clotting parameters in patients with pre-eclampsia.Journal of perinatal medicine, , Volume: 26, Issue:2, 1998
Reduced fetal exposure to aspirin using a novel controlled-release preparation in normotensive and hypertensive pregnancies.British journal of obstetrics and gynaecology, , Volume: 105, Issue:7, 1998
Vasoactive mediators in pregnancy-induced hypertensive disorders: a longitudinal study.American journal of obstetrics and gynecology, , Volume: 179, Issue:6 Pt 1, 1998
[Oral low-dose magnesium gluconate preventing pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 32, Issue:10, 1997
Effects of anti-endothelial cell antibody in pre-eclampsia on endothelin-1 release from cultured endothelial cells.Immunology and cell biology, , Volume: 75, Issue:4, 1997
Altered release of endothelin-1,2 and thromboxane B2 from trophoblastic cells in pre-eclampsia.European journal of clinical investigation, , Volume: 26, Issue:1, 1996
Preeclampsia: the effects of serum on endothelial cell prostacyclin, endothelin, and cell membrane integrity.American journal of obstetrics and gynecology, , Volume: 174, Issue:2, 1996
Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat.Prostaglandins, , Volume: 52, Issue:1, 1996
In-vitro secretion of prostanoids by placental villous cytotrophoblasts in pre-eclampsia.Placenta, , Volume: 17, Issue:7, 1996
Distinct factors in plasma of preeclamptic women increase endothelial nitric oxide or prostacyclin.Hypertension (Dallas, Tex. : 1979), , Volume: 28, Issue:5, 1996
Effect of serum on secretion of prostacyclin and endothelin-1 by decidual endothelial cells from normal and preeclamptic pregnancies.American journal of obstetrics and gynecology, , Volume: 173, Issue:3 Pt 1, 1995
Determination of mineral, parathyroid hormone, and 6-keto-prostaglandin-F1 alpha levels in pregnant women with hypertension and pre-eclampsia.Singapore medical journal, , Volume: 36, Issue:6, 1995
Hypertensive and normal pregnancy: a longitudinal study of blood pressure, distensibility of dorsal hand veins and the ratio of the stable metabolites of thromboxane A2 and prostacyclin in plasma.British journal of obstetrics and gynaecology, , Volume: 102, Issue:11, 1995
Trophoblast and placental villous core production of lipid peroxides, thromboxane, and prostacyclin in preeclampsia.The Journal of clinical endocrinology and metabolism, , Volume: 80, Issue:6, 1995
[Effect of trapidil in prevention of pre-eclampsia and fetal retardation].Zentralblatt fur Gynakologie, , Volume: 117, Issue:1, 1995
Plasma and urinary endothelin 1, prostacyclin metabolites and platelet consumption in pre-eclampsia and essential hypertensive pregnancy.Blood pressure, , Volume: 3, Issue:1-2, 1994
Impaired renin stimulation in pre-eclampsia.Clinical science (London, England : 1979), , Volume: 86, Issue:5, 1994
[Value of prostaglandins in a pre-eclampsia-equivalent animal model].Zentralblatt fur Gynakologie, , Volume: 116, Issue:5, 1994
Excretion of prostacyclin and thromboxane metabolites before, during, and after pregnancy-induced hypertension.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 57, Issue:1, 1994
[Vasoactive prostanoids and inhibitors of blood coagulation in pregnancy-induced hypertension].Zentralblatt fur Gynakologie, , Volume: 116, Issue:6, 1994
Production of prostacyclin and thromboxane A2 in mononuclear cells from preeclamptic women.American journal of obstetrics and gynecology, , Volume: 169, Issue:5, 1993
Urinary excretion of 6-keto-PGF1 alpha TxB2 and PGE2 in a rat animal model for preeclampsia-like syndrome.Prostaglandins, , Volume: 46, Issue:2, 1993
Endothelial vasoactive mediators in preeclampsia.American journal of obstetrics and gynecology, , Volume: 169, Issue:1, 1993
Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia.American journal of obstetrics and gynecology, , Volume: 167, Issue:4 Pt 1, 1992
Umbilical and uterine Doppler velocimetry and prostaglandin levels in preeclampsia.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, , Volume: 11, Issue:2, 1992
[A trial of low-dose aspirin therapy in high-risk pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:7, 1992
[Urinary 11-dehydrothromboxane B2 and 6-keto-prostaglandin F1 alpha in normal pregnant women and in women complicated with pregnancy-induced hypertension].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:6, 1992
[Mechanism and effect of anisodamine on uteroplacental circulation in pregnancy-induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 27, Issue:4, 1992
Sera from preeclamptic patients contain factor(s) that stimulate prostacyclin production by human endothelial cells.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:3, 1992
Endothelium-derived prostacyclin: effect of serum from women with normal and hypertensive pregnancy.Clinical science (London, England : 1979), , Volume: 82, Issue:4, 1992
Preliminary evidence for homoeostatic mechanism regulating endothelin production in pre-eclampsia.Lancet (London, England), , Apr-20, Volume: 337, Issue:8747, 1991
Maternal and fetal atrial natriuretic peptide levels, maternal plasma renin activity, angiotensin II, prostacyclin and thromboxane A2 levels in normal and preeclamptic pregnancies.The Tohoku journal of experimental medicine, , Volume: 165, Issue:2, 1991
Sera from preeclamptic women increase the content of triglycerides and reduce the release of prostacyclin in cultured endothelial cells.Thrombosis research, , Aug-01, Volume: 63, Issue:3, 1991
The role of aggregation of platelets in pregnancy-induced hypertension: a comprehensive and longitudinal study.International journal of cardiology, , Volume: 33, Issue:1, 1991
The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal blood.American journal of obstetrics and gynecology, , Volume: 165, Issue:6 Pt 1, 1991
[Low-dose aspirin preventing pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 26, Issue:6, 1991
[Prostaglandin E2, F2 alpha,6-keto-prostaglandin F1 alpha and thromboxane B2 in the placenta of normotensive women and women with pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 24, Issue:6, 1989
Urinary excretion of prostacyclin metabolites in infants born after maternal preeclampsia or with birth asphyxia.Biology of the neonate, , Volume: 56, Issue:2, 1989
[Feto-placental microcirculation and pathologic changes of the chorionic villi in pregnancy-induced hypertension syndrome].Zhonghua yi xue za zhi, , Volume: 68, Issue:11, 1988
Urinary excretion of 6-keto prostaglandin F1 alpha in pre-eclampsia.Archives of gynecology and obstetrics, , Volume: 244, Issue:1, 1988
[Synthesis of prostaglandins and lipid peroxidation in pregnant women with gestosis].Akusherstvo i ginekologiia, , Issue:6, 1988
[Plasma 6-keto-prostaglandin F1 alpha and thromboxane B2 levels in normal pregnancy and pregnancy-induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 23, Issue:1, 1988
Radioimmunoassay of thromboxane B2 and its preliminary applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:1, 1988
Prostacyclin and thromboxane in pregnancy-induced hypertension.Chinese medical journal, , Volume: 101, Issue:12, 1988
Reduced excretion of vasodilator prostaglandins in preeclampsia.Agents and actions. Supplements, , Volume: 22, 1987
[6-keto-prostaglandin F1 alpha and thromboxane B2 in the amniotic fluid and peripheral venous blood in healthy pregnant patients and in pregnant patients with pre-eclampsia].Zentralblatt fur Gynakologie, , Volume: 109, Issue:23, 1987
Renal prostacyclin and thromboxane in normotensive and preeclamptic pregnant women and their infants.The Journal of clinical endocrinology and metabolism, , Volume: 63, Issue:6, 1986
Placental prostacyclin production in normal and toxemic pregnancies.American journal of obstetrics and gynecology, , Volume: 154, Issue:1, 1986
Prostacyclin and thromboxane A2 in preeclamptic umbilical circulation.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 15, 1985
Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids.Obstetrics and gynecology, , Volume: 65, Issue:1, 1985
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Failure of exogenous prostacyclin to change placental and fetal blood flow in preeclampsia.American journal of obstetrics and gynecology, , Mar-01, Volume: 151, Issue:5, 1985
6-Keto prostaglandin F1 alpha, thromboxane B2, and 13,14-dihydro-15-keto prostaglandin F concentrations of normotensive and preeclamptic patients during pregnancy, delivery, and the postpartum period.American journal of obstetrics and gynecology, , Jan-01, Volume: 151, Issue:1, 1985
Preeclampsia: an imbalance in placental prostacyclin and thromboxane production.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Increased thromboxane A2 production but normal prostacyclin by the placenta in hypertensive pregnancies.Prostaglandins, , Volume: 27, Issue:1, 1984
Amniotic fluid prostanoids in preeclampsia.Obstetrics and gynecology, , Volume: 64, Issue:1, 1984
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Amniotic fluid 6-keto-prostaglandin F1 alpha and thromboxane B2 during labor.American journal of obstetrics and gynecology, , Nov-15, Volume: 150, Issue:6, 1984
Evidence that prostacyclin deficiency is a specific feature in preeclampsia.American journal of obstetrics and gynecology, , Mar-15, Volume: 148, Issue:6, 1984
[Studies on platelet function in toxemia of pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 35, Issue:7, 1983
Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E.Nihon Sanka Fujinka Gakkai zasshi, , Volume: 35, Issue:5, 1983
Relation between umbilical prostacyclin production and blood-flow in the fetus.Lancet (London, England), , Apr-02, Volume: 1, Issue:8327, 1983
Prostacyclin and thromboxane during human pregnancy.Acta obstetricia et gynecologica Scandinavica. Supplement, , Volume: 113, 1983
Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies.American journal of obstetrics and gynecology, , Nov-01, Volume: 141, Issue:5, 1981
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods.The Journal of maternal-fetal medicine, , Volume: 9, Issue:3
beta-Carotene attenuates peroxide-induced vasoconstriction in the human placenta.Journal of the Society for Gynecologic Investigation, , Volume: 4, Issue:2
Prostaglandin I2 mediates weak vasodilatation in human placental microvessels.Biology of reproduction, , 12-01, Volume: 103, Issue:6, 2020
Maternal vitamin D deficiency increases the thromboxane/prostacyclin ratio through alterations in the one-carbon cycle in Wistar rats.BioFactors (Oxford, England), , Volume: 45, Issue:4, 2019
Prostacyclin, thromboxane and glomerular filtration rate are abnormal in sickle cell pregnancy.PloS one, , Volume: 12, Issue:9, 2017
Effect of hypertonic sodium chloride hydroxyethyl starch 40 on ET, TXB2, 6-keto-PGF1α, and ANP of preeclampsia in caesarean section.Clinical and experimental obstetrics & gynecology, , Volume: 42, Issue:1, 2015
Decrease in inflammatory response does not prevent placental dysfunction after fetal cardiac bypass in goats.The Journal of thoracic and cardiovascular surgery, , Volume: 143, Issue:2, 2012
Regulation of prostacyclin synthase expression and prostacyclin content in the pig endometrium.Theriogenology, , Volume: 78, Issue:9, 2012
[Effect of electroacupuncture at different frequencies on serum estradiol and progesterone levels in late-stage pregnancy rats].Zhen ci yan jiu = Acupuncture research, , Volume: 37, Issue:4, 2012
The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy.Prostaglandins & other lipid mediators, , Volume: 95, Issue:1-4, 2011
The biological investigation of prostacyclin in preeclamptic women seen reduced endothelial function.Hypertension in pregnancy, , Volume: 29, Issue:4, 2010
Low peripheral progesterone and late embryonic/early fetal loss in suckled beef and lactating dairy cows.Theriogenology, , Volume: 71, Issue:3, 2009
Quantitative characterization of prostaglandins in the uterus of early pregnant cattle.Reproduction (Cambridge, England), , Volume: 138, Issue:2, 2009
Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day.Alcoholism, clinical and experimental research, , Volume: 32, Issue:11, 2008
Predominant basal directional release of thromboxane, but not prostacyclin, by placental trophoblasts from normal and preeclamptic pregnancies.Placenta, , Volume: 29, Issue:1, 2008
Differential regulation of myometrial prostaglandin production by changes in length.American journal of obstetrics and gynecology, , Volume: 198, Issue:2, 2008
Increased phospholipase A2 and thromboxane but not prostacyclin production by placental trophoblast cells from normal and preeclamptic pregnancies cultured under hypoxia condition.Placenta, , Volume: 26, Issue:5, 2005
A prospective, longitudinal study of the renin-angiotensin system, prostacyclin and thromboxane in the first trimester of normal human pregnancy: association with birthweight.Human reproduction (Oxford, England), , Volume: 20, Issue:11, 2005
Endothelin-induced constriction of the ductus venosus in fetal sheep: developmental aspects and possible interaction with vasodilatory prostaglandin.British journal of pharmacology, , Volume: 142, Issue:4, 2004
17beta-estradiol up-regulates prostacyclin production in cultured human uterine myometrial cells via augmentation of both cyclooxygenase-1 and prostacyclin synthase expression.Journal of the Society for Gynecologic Investigation, , Volume: 11, Issue:7, 2004
Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders.Acta obstetricia et gynecologica Scandinavica, , Volume: 83, Issue:12, 2004
Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit.Prostaglandins & other lipid mediators, , Volume: 70, Issue:3-4, 2003
Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia.American journal of obstetrics and gynecology, , Volume: 188, Issue:4, 2003
Heterogeneity of microvascular endothelial cells isolated from human term placenta and macrovascular umbilical vein endothelial cells.European journal of cell biology, , Volume: 82, Issue:4, 2003
Signs of platelet activation, but not lipid peroxidation, in fetal blood associated with functional and structural umbilicoplacental lesions in pregnancies complicated by impaired glucose metabolism.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, , Volume: 12, Issue:3, 2002
Normalization of vasoactive changes in preeclampsia precedes clinical recovery.Hypertension in pregnancy, , Volume: 21, Issue:1, 2002
Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 282, Issue:4, 2002
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Production of vasoactive substances by human umbilical vein endothelial cells after incubation with serum from preeclamptic patients.European journal of obstetrics, gynecology, and reproductive biology, , Dec-01, Volume: 99, Issue:2, 2001
Increased thromboxane production in women with a history of venous thromboembolic event: effect of heparins.British journal of haematology, , Volume: 114, Issue:3, 2001
Urinary excretion of aquaporin-2 water channel during pregnancy.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, , Volume: 11, Issue:4, 2001
Hypoxia attenuates PGE(2)but increases prostacyclin and thromboxane production in human term villous trophoblast.Placenta, , Volume: 22, Issue:6, 2001
Vasoactive mediator release by fetal endothelial cells in intrauterine growth restriction and preeclampsia.American journal of obstetrics and gynecology, , Volume: 184, Issue:3, 2001
Cyclooxygenase-2 inhibitors constrict the fetal lamb ductus arteriosus both in vitro and in vivo.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 278, Issue:6, 2000
Maternal thromboxane and prostacyclin levels in relation to fetal birth weight.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 93, Issue:1, 2000
[Relationship between the alteration of 6-keto-PGF1 alpha and TXB2 in cervical mucus of patients with threatened preterm labor and the efficacy of magnesium sulfate treatment].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 31, Issue:1, 2000
Prostacyclin deficiency and reduced fetoplacental blood flow in pregnancy-induced hypertension and preeclampsia.Gynecologic and obstetric investigation, , Volume: 50, Issue:2, 2000
Effect of ethanol on thromboxane and prostacyclin production in the human placenta.Alcohol (Fayetteville, N.Y.), , Volume: 21, Issue:2, 2000
Oxytocin signaling in human myometrium is impaired by prolonged exposure to interleukin-1.Biology of reproduction, , Volume: 63, Issue:3, 2000
[The effect of plasma from women with preeclampsia on endothelial cells activators in vitro].Zhonghua fu chan ke za zhi, , Volume: 35, Issue:7, 2000
Effects of shear stress on eicosanoid gene expression and metabolite production in vascular endothelium as studied in a novel biomechanical perfusion model.Biochemical and biophysical research communications, , Mar-05, Volume: 269, Issue:1, 2000
Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy.Gynecologic and obstetric investigation, , Volume: 50, Issue:4, 2000
Altered fetal pituitary-adrenal function in the ovine fetus treated with RU486 and meloxicam, an inhibitor of prostaglandin synthase-II.Biology of reproduction, , Volume: 63, Issue:6, 2000
Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 63, Issue:4, 2000
Basal and interleukin-1beta-stimulated prostaglandin production from cultured human myometrial cells: differential regulation by corticotropin-releasing hormone.The Journal of clinical endocrinology and metabolism, , Volume: 84, Issue:6, 1999
AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta.The Journal of pharmacology and experimental therapeutics, , Volume: 290, Issue:1, 1999
Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study.JAMA, , Jul-28, Volume: 282, Issue:4, 1999
Maternal factors modulate the increase in vasoactive substances during rat pregnancy.Hypertension in pregnancy, , Volume: 18, Issue:1, 1999
Placental transfer of the thromboxane synthetase inhibitor ridogrel in the late-pregnant ewe.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 86, Issue:1, 1999
An imbalance between prostacyclin and thromboxane in relation to cerebral blood flow in neonates with maternal preeclampsia.Prostaglandins & other lipid mediators, , Volume: 58, Issue:1, 1999
Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia?Journal of hypertension, , Volume: 17, Issue:9, 1999
Effects of lipoproteins from pre-eclamptic women on umbilical endothelial cell 6-oxo-prostaglandin f1alpha and endothelin 1 synthesis, and nitric oxide synthase 3 mRNA expression.Clinical science (London, England : 1979), , Volume: 97, Issue:6, 1999
[The effect of inhibition of nitric oxide synthesis on vasoregulatory factors in pregnant rats].Zhonghua fu chan ke za zhi, , Volume: 34, Issue:9, 1999
[Study on tumor necrosis factor and pathogenesis of pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 34, Issue:6, 1999
Interleukin-8 stimulates placental prostacyclin production in preeclampsia.American journal of reproductive immunology (New York, N.Y. : 1989), , Volume: 42, Issue:6, 1999
A comparison of the effects of indomethacin and NS-398 (a selective prostaglandin H synthase-2 inhibitor) on implantation in the rat.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 61, Issue:5, 1999
Reduced fetal exposure to aspirin using a novel controlled-release preparation in normotensive and hypertensive pregnancies.British journal of obstetrics and gynaecology, , Volume: 105, Issue:7, 1998
Prostanoid production in the umbilicoplacental arterial tree relative to impaired glucose tolerance.Early human development, , Jan-09, Volume: 50, Issue:2, 1998
Magnesium sulfate attenuates peroxide-induced vasoconstriction in the human placenta.American journal of obstetrics and gynecology, , Volume: 178, Issue:1 Pt 1, 1998
Vasoactive mediators in pregnancy-induced hypertensive disorders: a longitudinal study.American journal of obstetrics and gynecology, , Volume: 179, Issue:6 Pt 1, 1998
Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 59, Issue:5, 1998
High glucose levels modulate eicosanoid production in uterine and placental tissue from non-insulin-dependent diabetic rats during late pregnancy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 58, Issue:6, 1998
[Study on relativity between oxygen free radical and thromboxane B2, 6-keto-PGF1 alpha during ligustrazine treatment of intrauterine growth retardation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:5, 1998
Effects of magnesium sulfate infusion upon clotting parameters in patients with pre-eclampsia.Journal of perinatal medicine, , Volume: 26, Issue:2, 1998
[Relationship between PGI2, TXA2 and threatened preterm].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 29, Issue:3, 1998
Intrauterine eicosanoid production in uncomplicated and hypertensive pregnancies: alterations of placental 12-hydroxyeicosatetraenoic acid.Advances in experimental medicine and biology, , Volume: 433, 1997
Immunosuppressive therapy for recurrent aborters with positive antiphospholipid antibodies and alteration of 6ketoPGF1 alpha/TXB2 ratio.Journal of perinatal medicine, , Volume: 25, Issue:6, 1997
Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study.American journal of obstetrics and gynecology, , Volume: 177, Issue:6, 1997
The effect of dexamethasone on CRH and prostanoid production from human term placenta.Prostaglandins, , Volume: 54, Issue:3, 1997
Indomethacin modifies the fetal hemodynamic response induced by percutaneous umbilical blood sampling.American journal of obstetrics and gynecology, , Volume: 177, Issue:4, 1997
Effects of anti-endothelial cell antibody in pre-eclampsia on endothelin-1 release from cultured endothelial cells.Immunology and cell biology, , Volume: 75, Issue:4, 1997
Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats.Biology of the neonate, , Volume: 72, Issue:3, 1997
Eicosanoid production by placental and amnion tissues from control and non-insulin-dependent diabetic rats. Influence of oxytocin in the incubating medium.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:6, 1997
[Oral low-dose magnesium gluconate preventing pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 32, Issue:10, 1997
[The effect of platelet activating factor on the biosynthesis of thromboxane A2 and prostaglandin I2 in human placental villi and umbilical artery].Zhonghua fu chan ke za zhi, , Volume: 32, Issue:4, 1997
Prostanoid excretion in incipient singleton and twin pregnancies.American journal of obstetrics and gynecology, , Volume: 174, Issue:5, 1996
[Level of endothelin-1,2,6-keto-pgf1-alpha and atrial natriuretic peptide in serum of pregnant women with late hypertension].Polskie Archiwum Medycyny Wewnetrznej, , Volume: 95, Issue:6, 1996
Distinct factors in plasma of preeclamptic women increase endothelial nitric oxide or prostacyclin.Hypertension (Dallas, Tex. : 1979), , Volume: 28, Issue:5, 1996
In-vitro secretion of prostanoids by placental villous cytotrophoblasts in pre-eclampsia.Placenta, , Volume: 17, Issue:7, 1996
Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat.Prostaglandins, , Volume: 52, Issue:1, 1996
Dose-related action of estradiol on placental prostanoid prediction.Prostaglandins, , Volume: 51, Issue:6, 1996
Release of vasoactive agents during cordocentesis: differences between normally grown and growth-restricted fetuses.American journal of obstetrics and gynecology, , Volume: 175, Issue:3 Pt 1, 1996
Altered release of endothelin-1,2 and thromboxane B2 from trophoblastic cells in pre-eclampsia.European journal of clinical investigation, , Volume: 26, Issue:1, 1996
Preeclampsia: the effects of serum on endothelial cell prostacyclin, endothelin, and cell membrane integrity.American journal of obstetrics and gynecology, , Volume: 174, Issue:2, 1996
Intrauterine infection and the effects of inflammatory mediators on prostaglandin production by myometrial cells from pregnant women.American journal of obstetrics and gynecology, , Volume: 174, Issue:2, 1996
Hypertensive and normal pregnancy: a longitudinal study of blood pressure, distensibility of dorsal hand veins and the ratio of the stable metabolites of thromboxane A2 and prostacyclin in plasma.British journal of obstetrics and gynaecology, , Volume: 102, Issue:11, 1995
Development of an enzyme-linked immunosorbent assay for 2,3-dinor-6-keto-prostaglandin F1 alpha in urine using a monoclonal antibody.Clinical biochemistry, , Volume: 28, Issue:4, 1995
Lack of association between Doppler velocimetry and synthesis of prostacyclin and thromboxane in umbilical cord vessels from growth retarded fetuses.Acta obstetricia et gynecologica Scandinavica, , Volume: 74, Issue:2, 1995
Effect of low-dose aspirin during pregnancy on fibrinolytic variables before and after parturition.American journal of obstetrics and gynecology, , Volume: 172, Issue:3, 1995
[Effect of trapidil in prevention of pre-eclampsia and fetal retardation].Zentralblatt fur Gynakologie, , Volume: 117, Issue:1, 1995
Trophoblast and placental villous core production of lipid peroxides, thromboxane, and prostacyclin in preeclampsia.The Journal of clinical endocrinology and metabolism, , Volume: 80, Issue:6, 1995
Prostacyclin and thromboxane in pregnant and nonpregnant women in response to exercise.Obstetrics and gynecology, , Volume: 85, Issue:6, 1995
Adriamycin-related hypertension in pregnant rats: response to a thromboxane receptor antagonist.Clinical science (London, England : 1979), , Volume: 88, Issue:6, 1995
Effect of serum on secretion of prostacyclin and endothelin-1 by decidual endothelial cells from normal and preeclamptic pregnancies.American journal of obstetrics and gynecology, , Volume: 173, Issue:3 Pt 1, 1995
Prostaglandin release from human cervical tissue in the first trimester of pregnancy after preoperative dilatation with hygroscopic tents.Prostaglandins, , Volume: 50, Issue:4, 1995
Prostanoid excretion before in vitro fertilization relates to the likelihood of pregnancy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:6, 1995
Determination of mineral, parathyroid hormone, and 6-keto-prostaglandin-F1 alpha levels in pregnant women with hypertension and pre-eclampsia.Singapore medical journal, , Volume: 36, Issue:6, 1995
Plasma and urinary endothelin 1, prostacyclin metabolites and platelet consumption in pre-eclampsia and essential hypertensive pregnancy.Blood pressure, , Volume: 3, Issue:1-2, 1994
Angiotensin II metabolic clearance rate and pressor responses in nonpregnant and pregnant women.American journal of obstetrics and gynecology, , Volume: 171, Issue:3, 1994
Effects of prostaglandin inhibition on the renal function curve during ovine pregnancy.American journal of obstetrics and gynecology, , Volume: 171, Issue:3, 1994
[Vasoactive prostanoids and inhibitors of blood coagulation in pregnancy-induced hypertension].Zentralblatt fur Gynakologie, , Volume: 116, Issue:6, 1994
Impaired renin stimulation in pre-eclampsia.Clinical science (London, England : 1979), , Volume: 86, Issue:5, 1994
[Value of prostaglandins in a pre-eclampsia-equivalent animal model].Zentralblatt fur Gynakologie, , Volume: 116, Issue:5, 1994
Ridogrel improves maternal/fetal homeostasis in an ovine model of pregnancy-induced hypertension.Prostaglandins, , Volume: 47, Issue:3, 1994
Adrenergic regulation of prostaglandin biosynthesis in cultured rabbit gastric epithelial cells.Japanese journal of pharmacology, , Volume: 65, Issue:2, 1994
Reduced thromboxane receptor affinity and vasoconstrictor responses in placentae from diabetic pregnancies.Placenta, , Volume: 15, Issue:8, 1994
Role of prostaglandin E2 and prostacyclin in nonshivering thermogenesis during simulated birth in utero.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:5, 1994
Cocaine alters placental production of thromboxane and prostacyclin.American journal of obstetrics and gynecology, , Volume: 171, Issue:4, 1994
Excretion of prostacyclin and thromboxane metabolites before, during, and after pregnancy-induced hypertension.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 57, Issue:1, 1994
Biologic effects of parenteral bisulfite on human vascular tissue.Pediatric research, , Volume: 33, Issue:4 Pt 1, 1993
The effect of acetaminophen on prostacyclin production in pregnant women.American journal of obstetrics and gynecology, , Volume: 168, Issue:4, 1993
Endotoxin-induced fetal growth retardation in the pregnant guinea pig.American journal of obstetrics and gynecology, , Volume: 168, Issue:2, 1993
The effect of endothelins on nitric oxide and prostacyclin production from human umbilical vein, porcine aorta and bovine carotid artery endothelial cells in culture.British journal of pharmacology, , Volume: 109, Issue:4, 1993
Calcium modulation of endothelium-derived prostacyclin production in ovine pregnancy.Endocrinology, , Volume: 132, Issue:6, 1993
Metabolism of arachidonic acid by caruncular and allantochorionic tissues in cows with retained fetal membranes (RFM).Prostaglandins, , Volume: 45, Issue:1, 1993
Effects of a thromboxane synthetase inhibitor on platelet function; possible risks of use in pregnancy.Prostaglandins, , Volume: 46, Issue:1, 1993
Mechanisms of vasodilatation in pregnancy: studies of the role of prostaglandins and nitric-oxide in changes of vascular reactivity in the in situ blood perfused mesentery of pregnant rats.British journal of pharmacology, , Volume: 109, Issue:2, 1993
Eicosanoid production by intrauterine tissues before and after labor in short-term tissue culture.Prostaglandins, , Volume: 45, Issue:6, 1993
Effects of ridogrel on the prostacyclin-thromboxane ratio in nulliparous third trimester-pregnant rhesus monkeys.Prostaglandins, , Volume: 45, Issue:6, 1993
Correlation between umbilical artery resistance index, 6 ketoprostaglandin F1 alpha and thromboxane B2 in the fetoplacental compartment in patients with pregnancy induced hypertension.Prostaglandins, , Volume: 45, Issue:6, 1993
Endothelial vasoactive mediators in preeclampsia.American journal of obstetrics and gynecology, , Volume: 169, Issue:1, 1993
Gangliosides stimulate synthesis of prostaglandin E2 and prostacyclin in fetal rat brain hemispheres after episodes of global intrauterine ischemia.Journal of neuroscience research, , Nov-01, Volume: 36, Issue:4, 1993
Prostacyclin, thromboxane and antioxidant levels in pregnancy-induced hypertension.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 50, Issue:3, 1993
Effect of IGF-1 on placental prostanoid production.Prostaglandins, , Volume: 46, Issue:4, 1993
[Correlation between serotonin and prostaglandins in peritoneal fluid collected from patients with pelvic congestion].Zhonghua fu chan ke za zhi, , Volume: 28, Issue:6, 1993
[Effect of 3,4-dihydroxyacetophenone treatment on intrauterine growth retardation].Zhonghua fu chan ke za zhi, , Volume: 28, Issue:6, 1993
Production of prostacyclin and thromboxane A2 in mononuclear cells from preeclamptic women.American journal of obstetrics and gynecology, , Volume: 169, Issue:5, 1993
Peroxide induces vasoconstriction in the human placenta by stimulating thromboxane.American journal of obstetrics and gynecology, , Volume: 169, Issue:4, 1993
Urinary excretion of 6-keto-PGF1 alpha TxB2 and PGE2 in a rat animal model for preeclampsia-like syndrome.Prostaglandins, , Volume: 46, Issue:2, 1993
Effects of onapristone on uterine prostaglandin production and plasma progesterone concentrations in guinea-pigs during early and mid-pregnancy.Journal of reproduction and fertility, , Volume: 99, Issue:2, 1993
Prostacyclin (PGI2) protects rat cortical neurons in culture against hypoxia/reoxygenation and glutamate-induced injury.Neuroscience letters, , Sep-17, Volume: 160, Issue:1, 1993
[Production of prostacyclin in human umbilical cord blood vessels. Effect of natural and synthetic estrogen].Zentralblatt fur Gynakologie, , Volume: 114, Issue:8, 1992
Prostaglandin E production by uteri of ovariectomized pregnant rats receiving antiprogesterone steroid or in which progesterone has been withdrawn.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 47, Issue:1, 1992
Increased prostaglandin concentrations in the cervical mucus of pregnant women with bacterial vaginosis.Prostaglandins, , Volume: 43, Issue:2, 1992
Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia.American journal of obstetrics and gynecology, , Volume: 167, Issue:4 Pt 1, 1992
Study of thromboxane and prostacyclin metabolism in an in vitro model of first-trimester human trophoblast.American journal of obstetrics and gynecology, , Volume: 167, Issue:4 Pt 1, 1992
Umbilical and uterine Doppler velocimetry and prostaglandin levels in preeclampsia.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, , Volume: 11, Issue:2, 1992
Responses of placental steroids, prostacyclin and thromboxane A2 to thermal stress during pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Jan-31, Volume: 43, Issue:2, 1992
Sera from preeclamptic patients contain factor(s) that stimulate prostacyclin production by human endothelial cells.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:3, 1992
Production of prostaglandin by late-gestation porcine placental cells in vitro.Journal of reproduction and fertility, , Volume: 95, Issue:1, 1992
Effect of ethanol on the release of prostaglandins from ovine fetal brain stem during gestation.Alcoholism, clinical and experimental research, , Volume: 16, Issue:3, 1992
The regulation of endothelin production in human umbilical vein endothelial cells: unique inhibitory action of calcium ionophores.The Journal of clinical endocrinology and metabolism, , Volume: 75, Issue:2, 1992
Any physiological role for prostacyclin in regulation of fetal vessel tone?Agents and actions. Supplements, , Volume: 37, 1992
Endothelium-derived prostacyclin: effect of serum from women with normal and hypertensive pregnancy.Clinical science (London, England : 1979), , Volume: 82, Issue:4, 1992
[Investigation of maternal peripheral plasma concentration of PG in induction of labor by nutrition food inductive drug].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 14, Issue:6, 1992
[Mechanism and effect of anisodamine on uteroplacental circulation in pregnancy-induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 27, Issue:4, 1992
Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin.American journal of obstetrics and gynecology, , Volume: 166, Issue:1 Pt 1, 1992
Prostaglandin production by porcine allantochorion in vitro: effect of cortisol infusion in vivo.Canadian journal of physiology and pharmacology, , Volume: 70, Issue:7, 1992
Prostaglandin production in the umbilical and uterine circulations in pregnant sheep at 129-136 days gestation.Journal of developmental physiology, , Volume: 17, Issue:2, 1992
[A trial of low-dose aspirin therapy in high-risk pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:7, 1992
[Urinary 11-dehydrothromboxane B2 and 6-keto-prostaglandin F1 alpha in normal pregnant women and in women complicated with pregnancy-induced hypertension].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:6, 1992
Thromboxane dominance and prostacyclin deficiency in habitual abortion.Lancet (London, England), , Apr-13, Volume: 337, Issue:8746, 1991
Preliminary evidence for homoeostatic mechanism regulating endothelin production in pre-eclampsia.Lancet (London, England), , Apr-20, Volume: 337, Issue:8747, 1991
Maternal levels of prostacyclin, thromboxane, vitamin E, and lipid peroxides throughout normal pregnancy.American journal of obstetrics and gynecology, , Volume: 165, Issue:6 Pt 1, 1991
The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal blood.American journal of obstetrics and gynecology, , Volume: 165, Issue:6 Pt 1, 1991
[Low-dose aspirin preventing pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 26, Issue:6, 1991
Uterine production of prostaglandins F2 alpha and 6-keto-F1 alpha by ovariectomized pregnant rats receiving antiprogesterone steroid or in which progesterone has been withdrawn.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 44, Issue:4, 1991
Maternal and fetal atrial natriuretic peptide levels, maternal plasma renin activity, angiotensin II, prostacyclin and thromboxane A2 levels in normal and preeclamptic pregnancies.The Tohoku journal of experimental medicine, , Volume: 165, Issue:2, 1991
Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma.Cancer research, , Aug-15, Volume: 51, Issue:16, 1991
[Changes in parameters of hemorheology and circulation 6-keto-PGF1 alpha and TXB2 in dilated cardiomyopathy].Zhonghua nei ke za zhi, , Volume: 30, Issue:4, 1991
Stimulation by human chorionic gonadotropin of prostaglandin synthesis by early human placental tissue.The Journal of clinical endocrinology and metabolism, , Volume: 73, Issue:1, 1991
The role of aggregation of platelets in pregnancy-induced hypertension: a comprehensive and longitudinal study.International journal of cardiology, , Volume: 33, Issue:1, 1991
Nifedipine increases urinary excretion of prostacyclin metabolite in hypertensive pregnancy.Pharmacology & toxicology, , Volume: 69, Issue:1, 1991
Sera from preeclamptic women increase the content of triglycerides and reduce the release of prostacyclin in cultured endothelial cells.Thrombosis research, , Aug-01, Volume: 63, Issue:3, 1991
Endothelins in perinatal biology.Seminars in perinatology, , Volume: 15, Issue:1, 1991
Placental thromboxane and prostacyclin production in an ovine diabetic model.American journal of obstetrics and gynecology, , Volume: 163, Issue:6 Pt 1, 1990
[Alteration of prostaglandin I2 on ripening in rabbit uterine cervix].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 42, Issue:7, 1990
Low-dose aspirin. II. Relationship of angiotensin II pressor responses, circulating eicosanoids, and pregnancy outcome.American journal of obstetrics and gynecology, , Volume: 163, Issue:6 Pt 1, 1990
Correlation of leukocyte interleukin-1 production with the stimulation of prostaglandin and tissue factor synthesis by human umbilical vein endothelial cells.Agents and actions, , Volume: 31, Issue:1-2, 1990
Eicosanoid production in rabbit vascular tissues and placentas.The American journal of physiology, , Volume: 258, Issue:3 Pt 1, 1990
Extraction with methyl tert-butyl ether overcomes erratic elution patterns of 6-keto-prostaglandin F1 alpha on high pressure liquid chromatography.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:2, 1990
Leukotrienes and prostaglandins in fetal lung liquid.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 68, Issue:5, 1990
Retention of intrauterine fetal bone increases menstrual prostaglandins.Obstetrics and gynecology, , Volume: 75, Issue:3 Pt 2, 1990
Influence of an alpha-1-adrenoceptor antagonist, nicergoline, on placental prostanoid production in streptozotocin-induced diabetic pregnant rats.Biology of the neonate, , Volume: 57, Issue:3-4, 1990
Analysis of the responses of the fetal vessels of human perfused placental lobules to acute infusions of arachidonic acid.Reproduction, fertility, and development, , Volume: 2, Issue:5, 1990
Actions of endothelin-1 on prostaglandin production by gestational tissues.Prostaglandins, , Volume: 40, Issue:6, 1990
Prostacyclin versus thromboxane metabolite excretion: changes in pregnancy and labor.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 35, Issue:1, 1990
[Prostacyclin and metabolite assay and the clinical significance].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 48 Suppl, 1990
Prostaglandins: PGF2 alpha, PGE2, 6-keto-PGF1 alpha and TXB2 serum levels in dysmenorrheic adolescents before, during and after treatment with oral contraceptives.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 36, Issue:3, 1990
Eicosanoid production and transfer in the placenta of the diabetic pregnancy.Prostaglandins, , Volume: 40, Issue:2, 1990
Endothelial inositol phosphate generation and prostacyclin production in response to G-protein activation by AlF4-.The Biochemical journal, , Dec-15, Volume: 264, Issue:3, 1989
Thromboxane and prostacyclin production by different compartments of the human placental villus.The Journal of clinical endocrinology and metabolism, , Volume: 68, Issue:3, 1989
The relation between thromboxane and prostaglandin synthesis in human decidua tissue: a comparison of eicosanoid synthesis in minced tissue with that in a cell-free preparation.Biochimica et biophysica acta, , Mar-14, Volume: 1002, Issue:1, 1989
Urinary excretion of prostacyclin metabolites in infants born after maternal preeclampsia or with birth asphyxia.Biology of the neonate, , Volume: 56, Issue:2, 1989
Bradykinin produces pulmonary vasodilation in fetal lambs: role of prostaglandin production.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 67, Issue:4, 1989
Effects of 3,4-dihydroxyacetophenone on the biosynthesis of TXA2 and PGI2 in human placental villus and umbilical artery segments in vitro.Prostaglandins, , Volume: 38, Issue:4, 1989
Production of epoxygenase metabolite by human reproductive tissues.Prostaglandins, , Volume: 38, Issue:6, 1989
Prostacyclin release and cytotoxicity of peritoneal cells are inversely related in pregnant and non-pregnant mice infected with herpes simplex virus.American journal of reproductive immunology (New York, N.Y. : 1989), , Volume: 20, Issue:4, 1989
The excretion of prostacyclin (PGI2) in milk and its possible role as a vasodilator in the mammary gland of goats.Comparative biochemistry and physiology. A, Comparative physiology, , Volume: 93, Issue:2, 1989
Prostaglandin production by horse embryos and the effect of co-culture of embryos with endometrium from pregnant mares.Journal of reproduction and fertility, , Volume: 87, Issue:1, 1989
[Prostaglandin E2, F2 alpha,6-keto-prostaglandin F1 alpha and thromboxane B2 in the placenta of normotensive women and women with pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 24, Issue:6, 1989
Changes in plasma levels of PGF2 alpha and PGI2 metabolites at and after delivery at term.Prostaglandins, , Volume: 37, Issue:1, 1989
Uniqueness of dietary olive oil in stimulating aortic prostacyclin production in post-weanling rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 36, Issue:1, 1989
Effect of indomethacin administration on glucose homeostasis and pancreatic hormones in lactating goats.Journal of dairy science, , Volume: 72, Issue:5, 1989
Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.The New England journal of medicine, , Aug-10, Volume: 321, Issue:6, 1989
Increase in uterine prostaglandin E2, F2 alpha, prostacyclin and stability in thromboxane A2 production during late pregnancy in streptozotocin-induced diabetic rats.Prostaglandins, , Volume: 37, Issue:6, 1989
Effects of chronic fetal hyperinsulinemia on plasma arachidonic acid and prostaglandin concentrations.American journal of obstetrics and gynecology, , Volume: 161, Issue:4, 1989
[Comparative studies on steroidogenesis and prostaglandins production by luteal cells in newly formed corpora lutea and early pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 41, Issue:1, 1989
Changes in urinary 6-keto-prostaglandin F1 alpha excretion during pregnancy and labor.Prostaglandins, , Volume: 35, Issue:4, 1988
[Basic and clinical studies of angiotensin II pressor responsiveness in pregnancy-induced-hypertension].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 40, Issue:8, 1988
Release of prostacyclin (PGI2) from trophoblast in tissue culture: the effect of glucose concentration.Acta physiologica Hungarica, , Volume: 71, Issue:4, 1988
Low-dose aspirin inhibits thromboxane, but not prostacyclin, production by human placental arteries.American journal of obstetrics and gynecology, , Volume: 159, Issue:6, 1988
[Plasma 6-keto-prostaglandin F1 alpha and thromboxane B2 levels in normal pregnancy and pregnancy-induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 23, Issue:1, 1988
Pulmonary hemodynamics at birth: effect of acute cyclooxygenase inhibition in lambs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 64, Issue:4, 1988
Prostacyclin and thromboxane in pregnancy-induced hypertension.Chinese medical journal, , Volume: 101, Issue:12, 1988
Radioimmunoassay of thromboxane B2 and its preliminary applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:1, 1988
Altered excretion of prostaglandin and thromboxane metabolites in pregnancy-induced hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 11, Issue:6 Pt 1, 1988
In vitro renal eicosanoid production during pregnancy in rabbits.The American journal of physiology, , Volume: 254, Issue:6 Pt 1, 1988
Ritodrine infusion at term: effects on maternal and fetal prostacyclin, thromboxane and prostaglandin precursor fatty acids.Gynecologic and obstetric investigation, , Volume: 25, Issue:2, 1988
[Synthesis of prostaglandins and lipid peroxidation in pregnant women with gestosis].Akusherstvo i ginekologiia, , Issue:6, 1988
Maternal smoking and neonatal prostacyclin excretion.Developmental pharmacology and therapeutics, , Volume: 11, Issue:2, 1988
Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects.Obstetrics and gynecology, , Volume: 71, Issue:1, 1988
Urinary excretion of 6-keto prostaglandin F1 alpha in pre-eclampsia.Archives of gynecology and obstetrics, , Volume: 244, Issue:1, 1988
[Feto-placental microcirculation and pathologic changes of the chorionic villi in pregnancy-induced hypertension syndrome].Zhonghua yi xue za zhi, , Volume: 68, Issue:11, 1988
Beneficial effects of U-63,557A, a thromboxane synthetase inhibitor, in an ovine model of pregnancy-induced hypertension.American journal of obstetrics and gynecology, , Volume: 157, Issue:1, 1987
Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension.American journal of perinatology, , Volume: 4, Issue:2, 1987
Peripherally detectable hormones--their relation to the increased uterine activity during standing in pregnant women.Biological research in pregnancy and perinatology, , Volume: 8, Issue:1 1ST Half, 1987
Immunohistochemical localization of 6-keto-prostaglandin F1 alpha and prostaglandin E2 in the human umbilical cord before and after labor.Laboratory investigation; a journal of technical methods and pathology, , Volume: 56, Issue:5, 1987
Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension.Circulation, , Volume: 75, Issue:5, 1987
Enhanced prostaglandin synthesis in the parturient rat uterus and its effects on myometrial oxytocin receptor concentrations.Prostaglandins, , Volume: 34, Issue:6, 1987
Evaluation of platelet function in pregnancy. Comparative studies in non-smokers and smokers.Thrombosis research, , Apr-15, Volume: 46, Issue:2, 1987
Renal synthesis and urinary excretion of eicosanoids during pregnancy in rats.The American journal of physiology, , Volume: 253, Issue:6 Pt 2, 1987
Effects of progesterone withdrawal on uterine prostaglandin levels in the ovariectomized pregnant rat.Prostaglandins, leukotrienes, and medicine, , Volume: 29, Issue:1, 1987
Estrogen, progesterone, prolactin, prostaglandin E2, prostaglandin F2 alpha, 13,14-dihydro-15-keto-prostaglandin F2 alpha, and 6-keto-prostaglandin F1 alpha gradients across the uterus in women in labor and not in labor.American journal of obstetrics and gynecology, , Volume: 157, Issue:1, 1987
Effect of OKY-046, a selective thromboxane inhibitor, on prostaglandin production and function of pregnant rat uteri and platelets.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:1, 1987
[6-keto-prostaglandin F1 alpha and thromboxane B2 in the amniotic fluid and peripheral venous blood in healthy pregnant patients and in pregnant patients with pre-eclampsia].Zentralblatt fur Gynakologie, , Volume: 109, Issue:23, 1987
Effect of ethanol on thromboxane and prostacyclin synthesis by fetal platelets and umbilical artery.Life sciences, , Jul-20, Volume: 41, Issue:3, 1987
Alterations in reproductive tissue concentrations of oxytocin and prostaglandins during early pregnancy in the goat.Zentralblatt fur Veterinarmedizin. Reihe A, , Volume: 34, Issue:6, 1987
Low dose aspirin treatment in late pregnancy differentially inhibits cyclo-oxygenase in maternal platelets.Prostaglandins, , Volume: 34, Issue:5, 1987
Reduced excretion of vasodilator prostaglandins in preeclampsia.Agents and actions. Supplements, , Volume: 22, 1987
Production of prostacyclin, 6-keto-PGF1 alpha and thromboxane B2 by human umbilical vessels increases from the placenta towards the fetus.British journal of obstetrics and gynaecology, , Volume: 94, Issue:12, 1987
[Biosynthesis of prostaglandin in human cervical tissue].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 39, Issue:9, 1987
Effect of fetal and maternal intravascular antipyrine infusion on maternal plasma prostaglandin concentrations in the pregnant sheep at 104 to 127 days' gestation.American journal of obstetrics and gynecology, , Volume: 155, Issue:6, 1986
Vaginal and abdominal delivery increases maternal urinary 6-keto-prostaglandin F1 alpha excretion.British journal of obstetrics and gynaecology, , Volume: 93, Issue:9, 1986
Prostaglandin F2 alpha and prostacyclin imbalance in cows with placental retention: new findings.Annales de recherches veterinaires. Annals of veterinary research, , Volume: 17, Issue:4, 1986
Renal prostacyclin and thromboxane in normotensive and preeclamptic pregnant women and their infants.The Journal of clinical endocrinology and metabolism, , Volume: 63, Issue:6, 1986
[Detection of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human placental tissues].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 38, Issue:9, 1986
Placental thromboxane and prostacyclin in the regulation of placental blood flow.Obstetrics and gynecology, , Volume: 68, Issue:4, 1986
Comparative evaluation of antepartum and postpartum platelet function in smokers and nonsmokers.American journal of obstetrics and gynecology, , Volume: 155, Issue:6, 1986
Fetal and neonatal prostacyclin and thromboxane in relation to mode of delivery.Archives of disease in childhood, , Volume: 61, Issue:8, 1986
Altered angiotensin-prostanoid interactions in umbilical arteries in pregnancy-induced hypertension.Scandinavian journal of clinical and laboratory investigation. Supplementum, , Volume: 184, 1986
The effect of oxytocin and betamimetic stimulation on prostaglandin release in perfused human fetal placenta.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 23, Issue:3-4, 1986
Placental prostacyclin production in normal and toxemic pregnancies.American journal of obstetrics and gynecology, , Volume: 154, Issue:1, 1986
Effect of antipyrine on prostaglandin levels and uterine and umbilical blood flow.American journal of obstetrics and gynecology, , Volume: 155, Issue:6, 1986
Prostaglandins in human milk.Biology of the neonate, , Volume: 50, Issue:4, 1986
[Prostaglandin biosynthesis by pregnant myometrium].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 38, Issue:3, 1986
Comparison of plasma prostanoid levels in the human cord artery in normal and fetal distressed deliveries.Endocrinologia japonica, , Volume: 33, Issue:1, 1986
Placental biosynthesis and metabolism of prostanoids: special reference to guinea-pig during the last third of gestation.Prostaglandins, leukotrienes, and medicine, , Volume: 21, Issue:1, 1986
Prostaglandin concentrations in ovine maternal and fetal tissues at late gestation.Pediatric research, , Volume: 20, Issue:1, 1986
Prostaglandin output from the early pregnant rat uterus superfused in vitro, and the effect of A23187 and trifluoperazine.Journal of reproduction and fertility, , Volume: 74, Issue:1, 1985
Abnormalities in vascular arachidonic acid metabolism in the infant of the diabetic mother.British medical journal (Clinical research ed.), , Jun-08, Volume: 290, Issue:6483, 1985
Preeclampsia: an imbalance in placental prostacyclin and thromboxane production.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Cyclooxygenase and lipoxygenase pathways in the preimplantation rabbit uterus and blastocyst.Prostaglandins, , Volume: 29, Issue:3, 1985
In vitro prostacyclin production by ovine uterine and systemic arteries. Effects of angiotensin II.The Journal of clinical investigation, , Volume: 76, Issue:6, 1985
Prostacyclin concentrations in cord blood and in the newborn.Pediatrics, , Volume: 76, Issue:6, 1985
Influence of glucose, insulin and sera from diabetic patients on the prostacyclin synthesis in vitro in cultured human endothelial cells.Diabetologia, , Volume: 28, Issue:9, 1985
Prostacyclin in normal and hypertensive pregnancy.American journal of obstetrics and gynecology, , Nov-15, Volume: 153, Issue:6, 1985
Plasma six-keto-prostaglandin F1 alpha and endocrine pancreatic function in the newborn infant of the diabetic mother.Biology of the neonate, , Volume: 48, Issue:2, 1985
Has cervical smooth muscle any physiological role in the human?Acta physiologica Hungarica, , Volume: 65, Issue:3, 1985
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Ritodrine infusion during late pregnancy: effects on fetal and placental blood flow, prostacyclin, and thromboxane.American journal of obstetrics and gynecology, , Apr-15, Volume: 151, Issue:8, 1985
Failure of exogenous prostacyclin to change placental and fetal blood flow in preeclampsia.American journal of obstetrics and gynecology, , Mar-01, Volume: 151, Issue:5, 1985
Placental prostacyclin production in normal and toxemic pregnancies.American journal of obstetrics and gynecology, , Jan-01, Volume: 151, Issue:1, 1985
Progesterone and prostanoid production by bovine binucleate trophoblastic cells.Biology of reproduction, , Volume: 33, Issue:5, 1985
Reduced progesterone and altered cotyledonary prostaglandin values induced by locoweed (Astragalus lentiginosus) in sheep.American journal of veterinary research, , Volume: 46, Issue:9, 1985
[Effect of obstetrical manipulations on the prostaglandin content of the uterus].Zentralblatt fur Gynakologie, , Volume: 107, Issue:8, 1985
Further studies on prostaglandin and thromboxane production by the rat uterus during the oestrous cycle.Journal of reproduction and fertility, , Volume: 73, Issue:2, 1985
Prostanoid concentrations in maternal/fetal plasma and amniotic fluid and intrauterine tissue prostanoid output in relation to myometrial contractility during the onset of adrenocorticotropin-induced preterm labor in sheep.Endocrinology, , Volume: 116, Issue:1, 1985
Contributions of the fetoplacental unit to augmented uterine prostaglandin levels periparturition in the rat.Biology of reproduction, , Volume: 33, Issue:3, 1985
Delayed effects of experimental maternal diabetes on plasma cholesterol level and vascular prostacyclin synthesis in the offspring.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 179, Issue:4, 1985
Amniotic fluid prostaglandins do not reflect human fetal lung maturation.British journal of obstetrics and gynaecology, , Volume: 92, Issue:1, 1985
6-Keto prostaglandin F1 alpha, thromboxane B2, and 13,14-dihydro-15-keto prostaglandin F concentrations of normotensive and preeclamptic patients during pregnancy, delivery, and the postpartum period.American journal of obstetrics and gynecology, , Jan-01, Volume: 151, Issue:1, 1985
Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids.Obstetrics and gynecology, , Volume: 65, Issue:1, 1985
The effects of alpha- and beta-adrenergic stimulation on contractility and prostaglandin (prostaglandins E2 and F2 alpha and 6-keto-prostaglandin F1 alpha) production of pregnant human myometrial strips.American journal of obstetrics and gynecology, , Aug-01, Volume: 152, Issue:7 Pt 1, 1985
Prostaglandins in the fetal circulation following maternal ingestion of a prostaglandin synthetase inhibitor during mid-pregnancy.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, , Volume: 23, Issue:6, 1985
A mononuclear cell factor is a potent agonist of prostaglandin biosynthesis in cultured human fibroblasts and smooth muscle and endothelial cells.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 15, 1985
Prostacyclin and thromboxane A2 in preeclamptic umbilical circulation.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 15, 1985
Prostaglandins, renin-angiotensin system, and hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Abnormal concentrations of prostaglandins in amniotic fluid during delayed labour in multigravid patients.British journal of obstetrics and gynaecology, , Volume: 91, Issue:8, 1984
Prostaglandin synthesis in rat embryo tissue: the effect of non-steroidal anti-inflammatory drugs in vivo and ex vivo.Prostaglandins, , Volume: 27, Issue:5, 1984
Prostacyclin and maternal lupus anticoagulant.Lancet (London, England), , Jan-21, Volume: 1, Issue:8369, 1984
Mid-trimester pregnancy--a time of tranquility or activity?British journal of obstetrics and gynaecology, , Volume: 91, Issue:6, 1984
[Role of prostaglandin I2 (prostacyclin) on the maturation of human and rabbit uterine cervix].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 36, Issue:2, 1984
Effects of prostacyclin on fetal platelet function.Biological research in pregnancy and perinatology, , Volume: 5, Issue:1, 1984
Evidence that prostacyclin deficiency is a specific feature in preeclampsia.American journal of obstetrics and gynecology, , Mar-15, Volume: 148, Issue:6, 1984
Increased thromboxane A2 production but normal prostacyclin by the placenta in hypertensive pregnancies.Prostaglandins, , Volume: 27, Issue:1, 1984
Role of hydrogen peroxide in the neutrophil-mediated release of prostacyclin from cultured endothelial cells.The Journal of clinical investigation, , Volume: 74, Issue:2, 1984
Thromboxane A2 and prostacyclin levels in molar pregnancy.British journal of obstetrics and gynaecology, , Volume: 91, Issue:9, 1984
The onset of breathing at birth stimulates pulmonary vascular prostacyclin synthesis.Pediatric research, , Volume: 18, Issue:10, 1984
Amniotic fluid 6-keto-prostaglandin F1 alpha and thromboxane B2 during labor.American journal of obstetrics and gynecology, , Nov-15, Volume: 150, Issue:6, 1984
Production of prostacyclin, 6-keto-PGF1 alpha and thromboxane B2 by incubated samples of umbilical vessels: a comparison of methods for expressing the results on dry weight, wet weight, protein or DNA bases.Prostaglandins, , Volume: 28, Issue:2, 1984
Plasma prostaglandins during the intravenous infusion of angiotensin II in pregnant women.American journal of obstetrics and gynecology, , Dec-15, Volume: 150, Issue:8, 1984
Central venous concentrations of immunoreactive prostaglandins E, F, and 6-keto-prostaglandin F1 in eclampsia.British medical journal (Clinical research ed.), , May-19, Volume: 288, Issue:6429, 1984
Correlation of prostacyclin synthesis by human umbilical artery with status of essential fatty acid.American journal of obstetrics and gynecology, , Jun-15, Volume: 149, Issue:4, 1984
Mechanism of stimulation of pulmonary prostacyclin synthesis at birth.Prostaglandins, , Volume: 28, Issue:6, 1984
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Maternal thromboxane, prostacyclin, and umbilical blood flow in humans.Obstetrics and gynecology, , Volume: 63, Issue:5, 1984
Amniotic fluid prostanoids in preeclampsia.Obstetrics and gynecology, , Volume: 64, Issue:1, 1984
Effect of prenatal dexamethasone on immunoreactive 6-ketoprostaglandin F1 alpha levels in fetal rat lungs.Pediatric research, , Volume: 18, Issue:9, 1984
Influence of prostaglandins on contractility of the isolated human cervical muscle.Obstetrics and gynecology, , Volume: 63, Issue:3, 1984
Prostaglandin biosynthetic activities of isolated fetal lamb ductus arteriosus, other blood vessels, and lung tissue.Pediatric research, , Volume: 18, Issue:1, 1984
Endometrial prostaglandins and phospholipase activity related to implantation in rabbits: effects of dexamethasone.Biology of reproduction, , Volume: 30, Issue:3, 1984
Studies on ovarian prostaglandin production in relation to ovulation in the rat.Journal of reproduction and fertility, , Volume: 72, Issue:2, 1984
Concentrations of prostaglandins E2, F2 alpha and 6-keto-prostaglandin F1 alpha in the utero-ovarian venous plasma of nonpregnant and early pregnant ewes.Biology of reproduction, , Volume: 30, Issue:4, 1984
6-Keto prostaglandin F1 alpha, thromboxane B2 and 13,14-dihydro-15-keto prostaglandin F levels in maternal and fetal plasma.Prostaglandins, leukotrienes, and medicine, , Volume: 15, Issue:3, 1984
Studies on the control of prostaglandin production by the hypothalamus in relation to LH release in the rat.The Journal of endocrinology, , Volume: 103, Issue:2, 1984
Prostaglandin production by the early pregnant guinea-pig uterus in relation to implantation and luteal maintenance, and the effect of oestradiol.Journal of reproduction and fertility, , Volume: 72, Issue:1, 1984
Relation between umbilical prostacyclin production and blood-flow in the fetus.Lancet (London, England), , Apr-02, Volume: 1, Issue:8327, 1983
Lupus anticoagulant, recurrent abortion, and prostacyclin production by cultured smooth muscle cells.Lancet (London, England), , Nov-12, Volume: 2, Issue:8359, 1983
Prostaglandin stimulation of ornithine decarboxylase activity in mammary gland explants from mid-pregnant mice.Prostaglandins, , Volume: 25, Issue:3, 1983
Inhibition of prostacyclin synthesis in endothelial cells by methylisobutylxanthine is not mediated through elevated cAMP level.Biochimica et biophysica acta, , Dec-20, Volume: 754, Issue:3, 1983
[Studies on platelet function in toxemia of pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 35, Issue:7, 1983
Eicosapentaenoic acid and prostacyclin production by cultured human endothelial cells.Journal of lipid research, , Volume: 24, Issue:12, 1983
Maternal prostacyclin, thromboxane, and placental blood flow.American journal of obstetrics and gynecology, , Mar-15, Volume: 145, Issue:6, 1983
Effect of vacuum curettage on the concentrations of plasma 6-keto-prostaglandin F1 alpha and serum thromboxane B2.British journal of obstetrics and gynaecology, , Volume: 90, Issue:3, 1983
Prostacyclin and thromboxane during human pregnancy.Acta obstetricia et gynecologica Scandinavica. Supplement, , Volume: 113, 1983
Effect of infusion of PGI-2, 6-keto-PGF-1 alpha and PGF-2 alpha on luteal function in the pregnant rat.Journal of reproduction and fertility, , Volume: 69, Issue:1, 1983
Prostacyclin in complicated pregnancies.American journal of obstetrics and gynecology, , Nov-15, Volume: 147, Issue:6, 1983
Release of prostaglandins from intact fetal lamb ductus arteriosus.Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, , Volume: 61, Issue:5, 1983
Angiotensin II: a releaser of PGI2 from fetal and newborn rabbit lungs.Prostaglandins, , Volume: 25, Issue:6, 1983
Prostacyclin, prostaglandin F2 alpha and progesterone production by bovine luteal cells during the estrous cycle.Biology of reproduction, , Volume: 29, Issue:5, 1983
Effect of different amounts of arachidonic acid on vessel wall-generated PGI2 and TXA2.Prostaglandins, leukotrienes, and medicine, , Volume: 12, Issue:3, 1983
Experimental studies on the influence of prostaglandins on the connective tissue of the human cervix uteri.Acta obstetricia et gynecologica Scandinavica. Supplement, , Volume: 113, 1983
Angiotensin II induced release of prostaglandins from rat uterus.Archivos de biologia y medicina experimentales, , Volume: 16, Issue:1, 1983
Cervical dilatation by Lamicel--studies on the mechanism of action.British journal of obstetrics and gynaecology, , Volume: 90, Issue:11, 1983
Fetal-maternal secretion of prostaglandins in the cow.Prostaglandins, , Volume: 25, Issue:4, 1983
Effects of the fetal-placental unit on uterine prostaglandin levels at term in the pregnant rat.Prostaglandins, , Volume: 25, Issue:5, 1983
Estradiol-17 beta and 2-hydroxyestradiol-17 beta-induced differential production of prostaglandins by cells dispersed from human intrauterine tissues at parturition.Prostaglandins, , Volume: 25, Issue:5, 1983
Prostaglandin output in relation to parturition by cells dispersed from human intrauterine tissues.The Journal of clinical endocrinology and metabolism, , Volume: 57, Issue:4, 1983
Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E.Nihon Sanka Fujinka Gakkai zasshi, , Volume: 35, Issue:5, 1983
Plasma levels of prostaglandin metabolites in zinc-deficient female rats near term.The Journal of nutrition, , Volume: 113, Issue:4, 1983
Prostanoid content of human milk: relationships to milk fatty acid content.Endocrinologia experimentalis, , Volume: 17, Issue:3-4, 1983
Thromboxane and prostacyclin generation by intact human vessels in response to balloon catheter trauma.Prostaglandins, leukotrienes, and medicine, , Volume: 9, Issue:5, 1982
The effects of indomethacin on uterine activity and prostaglandin (PG) concentrations during labor induced by administering ACTH to fetal sheep.Canadian journal of physiology and pharmacology, , Volume: 60, Issue:9, 1982
The human placental anti-aggregating factor is neither prostacyclin, nor a prostacyclin metabolite.Prostaglandins, , Volume: 24, Issue:5, 1982
Prostaglandin biosynthesis by the rat uterus during the oestrus cycle, temporal correlation with plasma oestradiol and progesterone concentrations, identification of 6 keto PGF1 alpha as the major metabolite.Prostaglandins, , Volume: 23, Issue:3, 1982
Effect of the prostacyclin synthetase inhibitor tranylcypromine on uterine blood flow in pregnancy.Prostaglandins, , Volume: 23, Issue:2, 1982
Regulation of prostacyclin and thromboxane production by human umbilical vessels: the effect of estradiol and progesterone in a superfusion model.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:2, 1982
Prostaglandin production by the rabbit uterus and placenta in vitro.Journal of reproduction and fertility, , Volume: 66, Issue:2, 1982
Macrophage production of prostaglandins: effects of fetal calf serum and diazepam. Use of an improved method for extracting 6-keto-PGF1 alpha.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:6, 1982
Effect of amnioscopy on concentrations of prostaglandin F2 alpha, prostacyclin and thromboxane in maternal plasma.Gynecologic and obstetric investigation, , Volume: 13, Issue:3, 1982
Thromboxane B2, 6-keto-prostaglandin F1 alpha, and prostaglandin F2 alpha production by contracting pregnant rate uteri in vitro.Biology of reproduction, , Volume: 26, Issue:2, 1982
Alterations in reproductive tissue prostaglandins E and F, 6-keto-prostaglandin F1 alpha and thromboxane B2 with gestational age in the rat.Biology of reproduction, , Volume: 27, Issue:5, 1982
Gestational changes in prostanoid concentrations in intrauterine tissues and fetal fluids from pregnant sheep, and the relation to prostanoid output in vitro.Biology of reproduction, , Volume: 27, Issue:1, 1982
Plasma prostanoids in pregnancy-induced hypertension.British journal of obstetrics and gynaecology, , Volume: 89, Issue:8, 1982
Uterine prostaglandin concentrations following fetal death in sheep.Prostaglandins, , Volume: 23, Issue:3, 1982
Arachidonate metabolism in cultured human vascular endothelial cells. Evidence for two prostaglandin synthetic pathways sensitive to acetylsalicylic acid.Biochimica et biophysica acta, , Dec-13, Volume: 713, Issue:3, 1982
Interaction of nicotine and prostaglandins in the cardiovascular system.Prostaglandins, , Volume: 23, Issue:1, 1982
Surgery increases fetal plasma prostacyclin.Prostaglandins, , Volume: 24, Issue:3, 1982
Production of prostacyclin and thromboxane during cesarean section.Obstetrics and gynecology, , Volume: 60, Issue:5, 1982
In vitro production of prostaglandins E, F, and 6-keto prostaglandin F1 alpha by human pregnant uterus, decidua and amnion.Prostaglandins and medicine, , Volume: 6, Issue:4, 1981
Decrease prostacyclin production: a characteristic of chronic placental insufficiency syndromes.Lancet (London, England), , May-23, Volume: 1, Issue:8230, 1981
Uterine prostaglandin concentrations in sheep during late pregnancy and adrenocorticotropin-induced labor.Endocrinology, , Volume: 109, Issue:5, 1981
Human umbilical blood vessel converts all cis-5, 8, 11, 14, 17 eicosapentaenoic acid to prostaglandin I3.Prostaglandins, , Volume: 22, Issue:6, 1981
Effects of prostacyclin on the fetal pulmonary circulation.Pediatric pharmacology (New York, N.Y.), , Volume: 1, Issue:3, 1981
Ductus arteriosus closure may result from suppression of prostacyclin synthetase by an intrinsic hydroperoxy fatty acid.Prostaglandins, , Volume: 22, Issue:4, 1981
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
Maternal plasma levels of 6-keto-prostaglandin F1alpha during pregnancy and puerperium.Prostaglandins and medicine, , Volume: 7, Issue:2, 1981
Prostacyclin production increases during human parturition.British journal of obstetrics and gynaecology, , Volume: 88, Issue:5, 1981
Prostacyclin, thromboxane, and prostaglandin F2 alpha in maternal plasma during breast-feeding.American journal of obstetrics and gynecology, , Mar-15, Volume: 139, Issue:6, 1981
Increased prostacyclin synthesizing activity in human ripening uterine cervix.Prostaglandins, , Volume: 21, Issue:1, 1981
Measurement of prostaglandins in embryonic tissue using radioimmunoassay.Prostaglandins, , Volume: 22, Issue:4, 1981
Maternal plasma 6-oxo-prostaglandin F1 alpha levels throughout pregnancy: a longitudinal study.British journal of obstetrics and gynaecology, , Volume: 88, Issue:11, 1981
Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies.American journal of obstetrics and gynecology, , Nov-01, Volume: 141, Issue:5, 1981
Vascular 6-keto-prostaglandin F1 alpha production in term vaginal versus cesarean section deliveries.Prostaglandins and medicine, , Volume: 6, Issue:5, 1981
Studies on the involvement of prostaglandins in implantation in the rat.Journal of reproduction and fertility, , Volume: 62, Issue:1, 1981
Prostaglandin formation by the sheep embryo and endometrium as an indication of maternal recognition of pregnancy.Biology of reproduction, , Volume: 25, Issue:1, 1981
Concentrations of thromboxane B2 and 6-oxo-prostaglandin F1 alpha in amniotic fluid, decidual tissue, and placenta in the later stages of pregnancy in the rat.Advances in prostaglandin and thromboxane research, , Volume: 8, 1980
Prostaglandins in the human fetal circulation in mid-trimester and term pregnancy.Prostaglandins, , Volume: 20, Issue:4, 1980
6-Keto-PGF1 alpha: concentrations in human umbilical plasma and production by umbilical vessels.Advances in prostaglandin and thromboxane research, , Volume: 7, 1980
Prostaglandin synthetase activity in vascular tissue of male and female rats.Prostaglandins, , Volume: 19, Issue:6, 1980
Cadmium and glutathione: effect on human placental thromboxane and prostacyclin production.Reproductive toxicology (Elmsford, N.Y.), , Volume: 9, Issue:1
Prostacyclin and hormone levels in patients with symptoms of miscarriage and infection.Medicinski pregled, , Volume: 55, Issue:9-10
Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods.The Journal of maternal-fetal medicine, , Volume: 9, Issue:3
In vivo levels of prostaglandin F2 alpha, E2 and prostacyclin in the corpus luteum of pregnant and pseudopregnant rats.Biology of reproduction, , Volume: 42, Issue:5-6
Effect of IGF-I on placental thromboxane and prostacyclin release in severe intrauterine growth retardation.The Journal of maternal-fetal medicine, , Volume: 6, Issue:6
Does human placenta produce prostacyclin?Placenta, , Volume: 6, Issue:1
beta-Carotene attenuates peroxide-induced vasoconstriction in the human placenta.Journal of the Society for Gynecologic Investigation, , Volume: 4, Issue:2
Intravillous eicosanoid compartmentalization and regulation of placental blood flow.Journal of the Society for Gynecologic Investigation, , Volume: 4, Issue:2
Inhibition of tumor cell metastasis by modulation of the vascular prostacyclin/thromboxane A2 system.Clinical & experimental metastasis, , Volume: 1, Issue:2
Prostaglandin production by human chorion laeve cells in response to inflammatory mediators.Placenta, , Volume: 12, Issue:4
Effects of gestational age on prostaglandin production and its regulation in human myometrial cells.The Journal of maternal-fetal medicine, , Volume: 5, Issue:2
Thymic eicosanoid profiles and cyclooxygenase localization in prenatal and postnatal CBA/J mice.Regional immunology, , Volume: 3, Issue:6
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion.Clinical & experimental metastasis, , Volume: 19, Issue:7, 2002
Biochemical markers and skeletal metabolism in carcinoma of the prostate. Use of decision matrix theory and ROC analysis.British journal of urology, , Volume: 57, Issue:6, 1985
The possible role of circulating 6-oxo-PGF1 alpha in monitoring the growth and spread of malignant disease of the prostate.Progress in lipid research, , Volume: 20, 1981
[High-protein diet and high-grade proteinuria aggravate the progression of chronic renal failure in rats].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 5, Issue:3, 2007
Inhibitory effects of ligustrazine, a modulator of thromboxane-prostacycline-nitric oxide balance, on renal injury in rats with passive Heyman nephritis.Nephron. Physiology, , Volume: 98, Issue:3, 2004
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.The Journal of nutritional biochemistry, , Volume: 14, Issue:8, 2003
Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis.Kidney international, , Volume: 60, Issue:2, 2001
Impact of antihypertensive therapy on the skeleton: effects of enalapril and AT1 receptor antagonist losartan in female rats.Physiological research, , Volume: 50, Issue:4, 2001
Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 63, Issue:5, 2000
Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 27, Issue:8, 2000
[Experimental study of influence of yiqi huoxue serial recipes on basement membrane in membranous nephritis in rabbits].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 19, Issue:2, 1999
Effect of lipo-prostaglandin E1 on crescentic-type anti-glomerular basement membrane nephritis in rats.European journal of pharmacology, , May-01, Volume: 348, Issue:1, 1998
Effect of DP-1904, a thromboxane A2 synthase inhibitor, on passive Heymann nephritis in rats.European journal of pharmacology, , Nov-28, Volume: 316, Issue:1, 1996
Studies on the impact of dietary fat composition on proteinuria in diabetic rats.Diabetes research and clinical practice, , Volume: 33, Issue:1, 1996
Effects of flaxseed and flax oil diets in a rat-5/6 renal ablation model.American journal of kidney diseases : the official journal of the National Kidney Foundation, , Volume: 25, Issue:2, 1995
Effect of DP-1904, a thromboxane A2 synthetase inhibitor, on crescentic nephritis in rats.European journal of pharmacology, , Jul-11, Volume: 259, Issue:3, 1994
Production of prostacyclin and thromboxane A2 in mononuclear cells from preeclamptic women.American journal of obstetrics and gynecology, , Volume: 169, Issue:5, 1993
[Treatment of chronic renal failure with Oenothera beinnis L in rats with subtotal nephrectomy].Zhonghua nei ke za zhi, , Volume: 31, Issue:1, 1992
Studies on the antinephritic effect of plant components (4): Reduction of protein excretion by berberine and coptisine in rats with original-type anti-GBM nephritis.Japanese journal of pharmacology, , Volume: 59, Issue:2, 1992
Effect of protein intake and unilateral nephrectomy on renal function and eicosanoid excretion in rats.Mineral and electrolyte metabolism, , Volume: 18, Issue:2-5, 1992
Human and experimental studies on renal eicosanoid response to long-term cadmium exposure.Toxicology and applied pharmacology, , Volume: 116, Issue:2, 1992
[The effect of decreased thromboxane synthesis on proliferative glomerulonephritis].Casopis lekaru ceskych, , Oct-18, Volume: 130, Issue:16-17, 1991
Thromboxane synthesis inhibition increases renal prostacyclin and prevents renal disease progression in rats with remnant kidney.Journal of the American Society of Nephrology : JASN, , Volume: 1, Issue:5, 1990
Comparative efficacy of dietary treatments on renal function in rats with sub-total nephrectomy: renal polyunsaturated fatty acid incorporation and prostaglandin excretion.Clinical nephrology, , Volume: 33, Issue:1, 1990
Effects of a selective thromboxane synthetase inhibitor OKY-046 on experimental diabetic nephropathy.Nephron, , Volume: 56, Issue:3, 1990
Tumor necrosis factor induces glomerular damage in the rabbit.The American journal of pathology, , Volume: 134, Issue:2, 1989
Clinical effects of selective thromboxane A2 synthetase inhibitor in patients with nephrotic syndrome.Clinical nephrology, , Volume: 30, Issue:5, 1988
Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor.Prostaglandins, leukotrienes, and medicine, , Volume: 27, Issue:2-3, 1987
The effects of a thromboxane synthase inhibitor, a prostacyclin analog and PGE1 on the nephritis of the NZB/W F1 mouse.Clinical nephrology, , Volume: 28, Issue:6, 1987
Glomerular and hormonal responses to dietary protein intake in human renal disease.The American journal of physiology, , Volume: 253, Issue:6 Pt 2, 1987
6 Keto prostaglandin F1alpha plasma levels in aminonucleoside nephrosis in the rat.Prostaglandins, , Volume: 23, Issue:3, 1982
Role of prostaglandins on mechanical scratching-induced cutaneous barrier disruption in mice.Experimental dermatology, , Volume: 16, Issue:6, 2007
Prostaglandin D2 and prostaglandin E2 accelerate the recovery of cutaneous barrier disruption induced by mechanical scratching in mice.European journal of pharmacology, , Jul-25, Volume: 518, Issue:1, 2005
Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis.European journal of pharmacology, , Nov-28, Volume: 505, Issue:1-3, 2004
Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia.The American review of respiratory disease, , Volume: 142, Issue:1, 1990
Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model.Circulatory shock, , Volume: 21, Issue:3, 1987
Effect of cyclooxygenase blockade on gas exchange and hemodynamics in Pseudomonas pneumonia.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 63, Issue:5, 1987
Comparison of regional pulmonary perfusion in lobar pneumonia during high frequency and conventional mechanical ventilation in sheep.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 34, Issue:3 ( Pt 1), 1987
Effects of ibuprofen on a pig Pseudomonas ARDS model.The Journal of surgical research, , Volume: 40, Issue:5, 1986
Comparison of the postburn hyperdynamic state and changes in lung function (effect of wound bacterial content).Surgery, , Volume: 100, Issue:5, 1986
Ibuprofen modifies the inflammatory response of the murine lung to Pseudomonas aeruginosa.European journal of respiratory diseases, , Volume: 67, Issue:2, 1985
[The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses].Vestnik dermatologii i venerologii, , Issue:1, 1989
Cyclosporine and urinary prostaglandins.Transplantation proceedings, , Volume: 20, Issue:3 Suppl 3, 1988
Prostaglandins in human skin disease.The British journal of dermatology, , Volume: 109 Suppl 25, 1983
Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness.Journal of virology, , Volume: 78, Issue:19, 2004
Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep.The European respiratory journal, , Volume: 20, Issue:4, 2002
Hepatic involvement in pancreatitis-induced lung damage.The American journal of physiology, , Volume: 270, Issue:1 Pt 1, 1996
Intratracheal administration of DBcAMP attenuates edema formation in phosgene-induced acute lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 80, Issue:1, 1996
[Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 17, Issue:4, 1995
Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase.Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, , Volume: 10, Issue:3, 1995
Role of the bronchial circulation in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 76, Issue:1, 1994
Thromboxane receptor stimulation/inhibition and perfusion redistribution after acute lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 75, Issue:5, 1993
Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:1, 1993
Eicosanoid balance and perfusion redistribution of oleic acid-induced acute lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:5, 1992
Evidence of acute inflammatory response in reexpansion pulmonary edema.Chest, , Volume: 101, Issue:1, 1992
OKY-046 prevents increases in LTB4 and pulmonary edema in phorbol ester-induced lung injury in dogs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:6, 1992
Pentafraction reduces the lung lymph response after endotoxin administration in the ovine model.Circulatory shock, , Volume: 36, Issue:2, 1992
Release of von Willebrand factor antigen (vWF:Ag) and eicosanoids during acute injury to the isolated rat lung.The American review of respiratory disease, , Volume: 145, Issue:6, 1992
Pretreatment with catalase or dimethyl sulfoxide protects alloxan-induced acute lung edema in dogs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:4, 1992
Ridogrel prevents the thromboxane-mediated pressor response and oedema induced by hydrogen peroxide in isolated rabbit lungs.European journal of pharmacology, , Aug-16, Volume: 201, Issue:1, 1991
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.Annals of surgery, , Volume: 212, Issue:6, 1990
Cyclooxygenase inhibition in lungs or in neutrophils attenuates neutrophil-dependent edema in rat lungs perfused with phorbol myristate acetate.The Journal of pharmacology and experimental therapeutics, , Volume: 251, Issue:3, 1989
Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 67, Issue:5, 1989
Involvement of thromboxane in injury to isolated rat lungs perfused with phorbol myristate acetate in the presence and absence of neutrophils.Toxicology and applied pharmacology, , Volume: 91, Issue:1, 1987
Acute cigarette smoke exposure causes lung injury in rabbits treated with ibuprofen.Experimental lung research, , Volume: 13, Issue:2, 1987
Neutrophil depletion does not prevent lung edema after endotoxin infusion in goats.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 62, Issue:1, 1987
Ibuprofen prevents synthetic smoke-induced pulmonary edema.The American review of respiratory disease, , Volume: 134, Issue:6, 1986
The pulmonary lesion of smoke inhalation in an ovine model.Circulatory shock, , Volume: 18, Issue:4, 1986
Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid.British journal of pharmacology, , Volume: 84, Issue:2, 1985
Mechanisms of interaction between oxygen and granulocytes in hyperoxic lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 58, Issue:4, 1985
Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep.The American review of respiratory disease, , Volume: 132, Issue:3, 1985
Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Effect of endotoxemia on hypoxic pulmonary vasoconstriction in unanesthetized sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 58, Issue:5, 1985
Formation of prostanoids during intravascular complement activation in the rabbit.British journal of pharmacology, , Volume: 84, Issue:2, 1985
Lung edema due to hydrogen peroxide is independent of cyclooxygenase products.Journal of applied physiology: respiratory, environmental and exercise physiology, , Volume: 56, Issue:4, 1984
Platelet-activating factor raises airway and vascular pressures and induces edema in lungs perfused with platelet-free solution.The American review of respiratory disease, , Volume: 129, Issue:5, 1984
The effect of prostacyclin on increased hydraulic conductivity of pulmonary exchange vessels following microembolization in dogs.Microvascular research, , Volume: 26, Issue:2, 1983
Modification of inflammatory response to aspiration with ibuprofen.The American journal of physiology, , Volume: 243, Issue:6, 1982
Effect of contrast media on the formation of prostacyclin in isolated rat lungs.Acta radiologica: diagnosis, , Volume: 26, Issue:6
Effects of a fish oil diet on pigs' cardiopulmonary response to bacteremia.JPEN. Journal of parenteral and enteral nutrition, , Volume: 15, Issue:2
Effects of ulinastatin, an antiprotease, on alloxan-induced lung injury in dogs.Clinical therapeutics, , Volume: 14, Issue:3
Effects of Cydonia oblonga Miller extracts on blood hemostasis, coagulation and fibrinolysis in mice, and experimental thrombosis in rats.Journal of ethnopharmacology, , May-28, Volume: 154, Issue:1, 2014
[The effects of lupus anticoagulant on pulmonary thromboembolism].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 27, Issue:11, 2004
[Changes of the platelet function and serum anticardiolipin antibody in patients with pulmonary thromboembolism].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 27, Issue:11, 2004
Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism.The Journal of pharmacology and experimental therapeutics, , Volume: 310, Issue:3, 2004
[Changes of blood vessel active substances in acute pulmonary embolism induced by echinococus granulous cyst in rabbits].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 25, Issue:10, 2002
Coronary constriction and consequent cardiodepression in pulmonary embolism are mediated by pulmonary big endothelin and enhanced in early endothelial dysfunction.Critical care medicine, , Volume: 26, Issue:3, 1998
Prostanoid production and pulmonary hypertension after fat embolism are not modified by methylprednisolone.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 38, Issue:5, 1991
Corticosteroids do not inhibit acute pulmonary response to fat embolism.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 37, Issue:4 Pt 2, 1990
[Preliminary observation on plasma level of 5-HT, TXB2 and 6-keto-PGF1 alpha in TEPH].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 10, Issue:5, 1988
Pulmonary embolism: analysis of endothelial pore sizes in canine lung.The American journal of physiology, , Volume: 255, Issue:5 Pt 2, 1988
Effects of dibutyryl cAMP on pulmonary air embolism-induced lung injury in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 63, Issue:6, 1987
Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect.The American journal of physiology, , Volume: 252, Issue:3 Pt 2, 1987
Effects of Y-20811, a long-lasting thromboxane synthetase inhibitor, on thromboxane production and platelet function.Thrombosis research, , Aug-15, Volume: 43, Issue:4, 1986
Effect of thromboxane synthetase inhibitors (OKY-046, OKY-1580) on experimentally induced air embolism in anesthetized dogs.Prostaglandins, leukotrienes, and medicine, , Volume: 21, Issue:2, 1986
Prostaglandin production in patients with pulmonary embolism.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
The effect of prostacyclin infusion on increased pulmonary vascular permeability following microembolization in dogs.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
The effect of prostacyclin on increased hydraulic conductivity of pulmonary exchange vessels following microembolization in dogs.Microvascular research, , Volume: 26, Issue:2, 1983
The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs.Thrombosis research, , Apr-01, Volume: 30, Issue:1, 1983
Circulating negative inotropic agent(s) following pulmonary embolism.Surgery, , Volume: 91, Issue:4, 1982
[Effect of hypoxemia and pulmonary thromboembolism on plasma levels of 6-keto PGF 1 alpha, TxB, histamine and serotonin in anesthetized dogs (author's transl)].Nihon Kyobu Shikkan Gakkai zasshi, , Volume: 19, Issue:8, 1981
Treatment of pulmonary embolism with positive end-expiratory pressure and prostaglandin E1.Surgery, gynecology & obstetrics, , Volume: 153, Issue:2, 1981
The release of thromboxane B2 and 6-keto-PGF1 alpha following pulmonary embolism.Panminerva medica, , Volume: 31, Issue:4
Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine.Shock (Augusta, Ga.), , Volume: 2, Issue:5, 1994
The in vitro synthesis and degradation of prostaglandins during the development of bleomycin-induced pulmonary fibrosis in hamsters.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
Thromboxane and prostacyclin (epoprostenol) during exercise in diffuse pulmonary fibrosis.Lancet (London, England), , Nov-27, Volume: 2, Issue:8309, 1982
[Quantitive study of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human pulp].Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, , Volume: 34, Issue:4, 1999
Immunohistochemical demonstration of prostaglandins E2, F2 alpha, and 6-keto-prostaglandin F1 alpha in rat dental pulp with experimentally induced inflammation.Journal of endodontics, , Volume: 22, Issue:11, 1996
Involvement of arachidonic acid metabolites in increases in vascular permeability in experimental dental pulpal inflammation in the rat.Archives of oral biology, , Volume: 34, Issue:7, 1989
Arachidonic-acid metabolism in normal and experimentally-inflamed rat dental pulp.Archives of oral biology, , Volume: 32, Issue:10, 1987
Stability of prostacyclin in human and rabbit whole blood and plasma.Thrombosis research, , Aug-15, Volume: 43, Issue:4, 1986
Thrombotic thrombocytopenic purpura: treatment with nafazatrom.Clinical and laboratory haematology, , Volume: 6, Issue:2, 1984
Prostacyclin and thromboxane A2 in thrombotic thrombocytopenic purpura.British medical journal (Clinical research ed.), , Nov-21, Volume: 283, Issue:6303, 1981
Prostacyclin and haemolytic, thrombocytopenic microangiopathy.Lancet (London, England), , Sep-05, Volume: 2, Issue:8245, 1981
Anti-CENP-B and anti-TOPO-1-containing sera from systemic sclerosis-related diseases with Raynaud's phenomenon induce vascular endothelial cell senescence not via classical p53-p21 pathway.Clinical rheumatology, , Volume: 37, Issue:3, 2018
An imbalance in plasma prostanoids in patients with Raynaud's phenomenon and pulmonary vasospasm.The European respiratory journal, , Volume: 13, Issue:1, 1999
Treatment of severe Raynaud's syndrome by injection of autologous blood pretreated by heating, ozonation and exposure to ultraviolet light (H-O-U) therapy.International angiology : a journal of the International Union of Angiology, , Volume: 16, Issue:4, 1997
Plasma eicosanoids, platelet function and cold sensitivity.The British journal of surgery, , Volume: 76, Issue:4, 1989
Epoprostenol in patients with Raynaud's disease.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 33, Issue:1, 1988
Serum from patients with Raynaud's phenomenon inhibits prostacyclin production.The Journal of investigative dermatology, , Volume: 89, Issue:6, 1987
Prolonged remission in Raynaud's phenomenon after prostacyclin infusion.Scandinavian journal of rheumatology, , Volume: 15, Issue:4, 1986
Biosynthesis of thromboxane in patients with systemic sclerosis and Raynaud's phenomenon.British medical journal (Clinical research ed.), , Apr-19, Volume: 292, Issue:6527, 1986
Effect of dazoxiben, a thromboxane synthetase inhibitor on skin-blood flow following cold challenge in patients with Raynaud's phenomenon.European journal of clinical investigation, , Volume: 15, Issue:1, 1985
Increased prostacyclin metabolites and decreased red cell deformability in patients with systemic sclerosis and Raynauds syndrome.Prostaglandins, leukotrienes, and medicine, , Volume: 17, Issue:1, 1985
Dazoxiben, a thromboxane synthetase inhibitor, in Raynaud's phenomenon.Clinical pharmacology and therapeutics, , Volume: 36, Issue:1, 1984
Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon.Prostaglandins and medicine, , Volume: 7, Issue:5, 1981
Pulmonary prostacyclin is associated with less severe respiratory distress in preterm infants.Early human development, , Volume: 67, Issue:1-2, 2002
Prostacyclin concentrations and transitional circulation in preterm infants requiring mechanical ventilation.Archives of disease in childhood. Fetal and neonatal edition, , Volume: 80, Issue:1, 1999
Prostanoid and anti-thrombin III levels in premature infants.Advances in experimental medicine and biology, , Volume: 400B, 1997
Early postnatal dexamethasone therapy may lessen lung inflammation in premature infants with respiratory distress syndrome on mechanical ventilation.Pediatric pulmonology, , Volume: 23, Issue:3, 1997
[The role of prostaglandins in pathogenetic mechanisms of the respiratory distress syndrome in premature newborn infants].Akusherstvo i ginekologiia, , Issue:9, 1989
[Effect of artificial ventilation on the level of the prostacyclin metabolite 6-ketoprostaglandin F1 alpha in the plasma of newborn infants].Ginekologia polska, , Volume: 58, Issue:3, 1987
[New aspects on the pathogenesis of patent ductus arteriosus in premature infants].Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, , Volume: 134, Issue:7, 1986
Levels of 6-ketoprostaglandin F1 alpha in neonatal cerebrospinal fluid.Early human development, , Volume: 13, Issue:3, 1986
Ethamsylate reduces immunoreactive prostacyclin metabolite in low birthweight infants with respiratory distress syndrome.Early human development, , Volume: 14, Issue:3-4, 1986
Reduction of immunoreactive prostacyclin metabolite after paralysis in ventilated preterm infants.Early human development, , Volume: 13, Issue:1, 1986
Prostaglandins and echocardiography in the assessment of patent ductus arteriosus.Critical care medicine, , Volume: 14, Issue:5, 1986
Extracorporeal membrane oxygenation and congenital diaphragmatic hernia: modification of the pulmonary vasoactive profile.Journal of pediatric surgery, , Volume: 20, Issue:6, 1985
Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Effect of prenatal dexamethasone on immunoreactive 6-ketoprostaglandin F1 alpha levels in fetal rat lungs.Pediatric research, , Volume: 18, Issue:9, 1984
Urinary excretion rates of 6-keto-PGF1 alpha in preterm infants recovering from respiratory distress with and without patent ductus arteriosus.Pediatric research, , Volume: 18, Issue:6, 1984
Diuresis and respiratory distress syndrome: physiologic mechanisms and therapeutic implications.The Journal of pediatrics, , Volume: 102, Issue:6, 1983
Increased plasma immunoreactive 6-keto-prostaglandin F1 alpha levels in newborns with idiopathic respiratory distress syndrome.Pediatric research, , Volume: 16, Issue:10, 1982
[Dynamics of prostacyclin level in low-birth-weight infants with respiratory distress syndrome].Gematologiia i transfuziologiia, , Volume: 37, Issue:9-10
Partial liquid ventilation with FC-77 suppresses the release of lipid mediators in rat acute lung injury model.Critical care medicine, , Volume: 32, Issue:10, 2004
Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock.Critical care medicine, , Volume: 29, Issue:7, 2001
Dose-response to inhaled aerosolized prostacyclin for hypoxemia due to ARDS.Chest, , Volume: 117, Issue:3, 2000
Role of cyclooxygenase-2 in oleic acid-induced acute lung injury.American journal of respiratory and critical care medicine, , Volume: 160, Issue:4, 1999
Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration.American journal of respiratory and critical care medicine, , Volume: 159, Issue:2, 1999
A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep.Respirology (Carlton, Vic.), , Volume: 4, Issue:2, 1999
[The effect of cyclooxygenase-2 inhibitor on acute lung injury].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 22, Issue:6, 1999
Effects of various doses of antithrombin III on endotoxin-induced endothelial cell injury and coagulation abnormalities in rats.Thrombosis research, , Mar-01, Volume: 89, Issue:5, 1998
Synergistic hemodynamic effects of low-dose endotoxin and acute lung injury.American journal of respiratory and critical care medicine, , Volume: 157, Issue:6 Pt 1, 1998
Endothelin-1 and thromboxane A2 increase pulmonary vascular resistance in granulocyte-mediated lung injury.Critical care medicine, , Volume: 26, Issue:11, 1998
Eicosanoids and fat emulsions in acute respiratory distress syndrome patients.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 13, Issue:3, 1997
Leukocyte and platelet depletion with a blood cell separator: effects on lung injury after cardiac surgery with cardiopulmonary bypass.The Journal of thoracic and cardiovascular surgery, , Volume: 111, Issue:1, 1996
A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model.Critical care medicine, , Volume: 21, Issue:12, 1993
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
Effect of fast vs slow intralipid infusion on gas exchange, pulmonary hemodynamics, and prostaglandin metabolism.Chest, , Volume: 99, Issue:2, 1991
[Thromboxane and prostacyclin in endotoxin-induced lung injury].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 13, Issue:1, 1990
[The study of thromboxane A2 and prostacyclin in oleic acid-induced lung injury in dogs].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 12, Issue:1, 1989
Thromboxane and prostacyclin release in adult respiratory distress syndrome.Intensive care medicine, , Volume: 13, Issue:3, 1987
[Protective effect of PGI2 on experimental ARDS and factors influencing it].Zhonghua wai ke za zhi [Chinese journal of surgery], , Volume: 25, Issue:12, 1987
[Action of prostaglandin-like substances in rabbits with acute lung lesions].Zhonghua yi xue za zhi, , Volume: 67, Issue:8, 1987
Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model.Circulatory shock, , Volume: 21, Issue:3, 1987
Effects of ibuprofen on a pig Pseudomonas ARDS model.The Journal of surgical research, , Volume: 40, Issue:5, 1986
The pulmonary and systemic response to recurrent endotoxemia in the adult sheep.Surgery, , Volume: 100, Issue:5, 1986
Pulmonary microvascular injury induced by Pseudomonas aeruginosa cytotoxin in isolated rabbit lungs.Infection and immunity, , Volume: 52, Issue:3, 1986
Lung permeability and hemodynamics during endotoxemia: effect of aprotinin.The Journal of surgical research, , Volume: 41, Issue:6, 1986
The development of a model of subacute lung injury after intra-abdominal infection.Surgery, , Volume: 96, Issue:2, 1984
Biochemical pathways of acute lung injury.Bulletin europeen de physiopathologie respiratoire, , Volume: 21, Issue:3
Plasma prostanoids in neonatal extracorporeal membrane oxygenation. Influence of meconium aspiration.The Journal of thoracic and cardiovascular surgery, , Volume: 101, Issue:4, 1991
Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs.The American review of respiratory disease, , Volume: 143, Issue:4 Pt 1, 1991
The clinical significance of prostaglandins and thromboxane as mediators of septic shock.Klinische Wochenschrift, , Jan-15, Volume: 65, Issue:2, 1987
Prostaglandin and thromboxane levels during endotoxin-induced respiratory failure in pigs.Prostaglandins, leukotrienes, and medicine, , Volume: 28, Issue:3, 1987
Platelet function in acute respiratory failure.American journal of hematology, , Volume: 25, Issue:4, 1987
Thromboxane and prostacyclin in clinical acute respiratory failure.The Journal of surgical research, , Volume: 39, Issue:1, 1985
Role of serotonin in patients with acute respiratory failure.Annals of surgery, , Volume: 200, Issue:2, 1984
[Evaluation of various components of arachidonic acid metabolism of the subretinal fluid in aphakic eyes].Klinika oczna, , Volume: 90, Issue:6, 1988
[Thromboxane B2 and prostaglandin 6-keto-F1 alpha in the subretinal fluid].Klinika oczna, , Volume: 89, Issue:7, 1987
Prostacyclin and thromboxane A2 derivatives in rhegmatogenous subretinal fluid.Archives of ophthalmology (Chicago, Ill. : 1960), , Volume: 101, Issue:3, 1983
Prostaglandin levels of primary bone tumor tissues correlate with peritumoral edema demonstrated by magnetic resonance imaging.Cancer, , Jan-15, Volume: 79, Issue:2, 1997
Effects of interleukin-1 alpha on arachidonic acid metabolism in human osteosarcoma osteoblastic cells.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:1, 1993
Relationship of cAMP and calcium messenger systems in prostaglandin-stimulated UMR-106 cells.The Journal of biological chemistry, , Aug-05, Volume: 263, Issue:22, 1988
Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors.The American journal of pediatric hematology/oncology, ,Spring, Volume: 7, Issue:1, 1985
Cyclo-oxygenase products of arachidonic acid metabolism in rat osteoblasts in culture.Calcified tissue international, , Volume: 35, Issue:3, 1983
Anti-CENP-B and anti-TOPO-1-containing sera from systemic sclerosis-related diseases with Raynaud's phenomenon induce vascular endothelial cell senescence not via classical p53-p21 pathway.Clinical rheumatology, , Volume: 37, Issue:3, 2018
Silica-associated systemic sclerosis is clinically, serologically and immunologically indistinguishable from idiopathic systemic sclerosis.The British journal of dermatology, , Volume: 123, Issue:6, 1990
Plasma eicosanoids, platelet function and cold sensitivity.The British journal of surgery, , Volume: 76, Issue:4, 1989
Serum from patients with Raynaud's phenomenon inhibits prostacyclin production.The Journal of investigative dermatology, , Volume: 89, Issue:6, 1987
Biosynthesis of thromboxane in patients with systemic sclerosis and Raynaud's phenomenon.British medical journal (Clinical research ed.), , Apr-19, Volume: 292, Issue:6527, 1986
Increased prostacyclin metabolites and decreased red cell deformability in patients with systemic sclerosis and Raynauds syndrome.Prostaglandins, leukotrienes, and medicine, , Volume: 17, Issue:1, 1985
Prostaglandins in human skin disease.The British journal of dermatology, , Volume: 109 Suppl 25, 1983
Determination of 6-keto prostaglandin F1α and its metabolites in human plasma by LC-MS/MS.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, , Jul-15, Volume: 901, 2012
Setting up a 2D-LC/MS/MS method for the rapid quantitation of the prostanoid metabolites 6-oxo-PGF(1alpha) and TXB2 as markers for hemostasis assessment.Journal of mass spectrometry : JMS, , Volume: 44, Issue:3, 2009
Prostacyclin/thromboxane early changes in pregnancies that are complicated by preeclampsia.American journal of obstetrics and gynecology, , Volume: 188, Issue:4, 2003
Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep.The European respiratory journal, , Volume: 20, Issue:4, 2002
Determination of prostacyclin in plasma through a bioluminescent immunoassay for 6-keto-prostaglandin F1alpha: implication of dosage in patients with primary pulmonary hypertension.Analytical chemistry, , Aug-01, Volume: 74, Issue:15, 2002
Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine.Journal of chromatography. A, , Jul-14, Volume: 885, Issue:1-2, 2000
Quantitative analysis of small-subunit rRNA genes in mixed microbial populations via 5'-nuclease assays.Applied and environmental microbiology, , Volume: 66, Issue:11, 2000
Microdetermination of the 6,15-diketo-13,14-dihydroprostaglandin F1alpha in human plasma using gas chromatography/selected ion monitoring with [18O]6,15-diketo-13,14-dihydro-prostaglandin F1alpha as an internal standard.Prostaglandins & other lipid mediators, , Volume: 58, Issue:2-4, 1999
Response of intra-acinar pulmonary microvessels to hypoxia, hypercapnic acidosis, and isocapnic acidosis.Circulation research, , Apr-06, Volume: 82, Issue:6, 1998
Effect of neuropeptide Y on bradykinin-induced release of prostacyclin and thromboxane from guinea pig perfused lung.Canadian journal of physiology and pharmacology, , Volume: 75, Issue:6, 1997
Evaluation of enzyme-linked immunosorbent assays for quantitation of eicosanoid mediators of sepsis syndrome.Shock (Augusta, Ga.), , Volume: 6, Issue:2, 1996
Microdetermination of 2,3-dinor-6-ketoprostaglandin F1 alpha in human urine using gas chromatography-high-resolution selected-ion monitoring.Journal of chromatography. B, Biomedical applications, , Aug-05, Volume: 658, Issue:1, 1994
Application of an alpha-sidechain length-specific monoclonal antibody to immunoaffinity purification and enzyme immunoassay of 2,3-dinor-6-keto-prostaglandin F1 alpha from human urine.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 50, Issue:2, 1994
Vitamin E binds to specific binding sites and enhances prostacyclin production by cultured aortic endothelial cells.Thrombosis and haemostasis, , Dec-07, Volume: 68, Issue:6, 1992
Specific neutrophil elastase inhibitor does not attenuate acute lung injury induced by air embolism in awake sheep.Experimental lung research, , Volume: 22, Issue:6
Effect of Ibuprofen on interleukin-1beta-induced abnormalities in hemodynamics and oxygen metabolism in rabbits.Shock (Augusta, Ga.), , Volume: 20, Issue:6, 2003
Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns.Burns : journal of the International Society for Burn Injuries, , Volume: 24, Issue:8, 1998
Beneficial effects of BAY u3405, a novel thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock.Pharmacology, , Volume: 49, Issue:6, 1994
A prospective clinical study on the pathogenesis of multiple organ failure in severely burned patients.Burns : journal of the International Society for Burn Injuries, , Volume: 18, Issue:1, 1992
Protective effects of G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock.Journal of cardiovascular pharmacology, , Volume: 19, Issue:1, 1992
[Plasma renin activity, angiotensin II, angiotensin converting enzyme, thromboxane A2 and prostacyclin I2 levels in pigs with severe hypoxia and hypercapnea and acidosis shock].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 15, Issue:1, 1992
Platelet activating factor involvement in splanchnic artery occlusion shock in rats.European journal of pharmacology, , Jan-03, Volume: 192, Issue:1, 1991
Interactions between platelet-activating factor and prostanoids during mesenteric ischemia-reperfusion-induced shock in the anesthetized dog.Circulatory shock, , Volume: 35, Issue:1, 1991
Intestinal and arterial plasma thromboxane and prostacyclin levels in shock: effects of indomethacin.The Journal of surgical research, , Volume: 47, Issue:6, 1989
Thromboxane and prostacyclin release in adult respiratory distress syndrome.Intensive care medicine, , Volume: 13, Issue:3, 1987
Inhibition of thromboxane biosynthesis in splanchnic ischemia shock.Circulatory shock, , Volume: 18, Issue:2, 1986
Acute circulatory collapse caused by platelet-activating factor (PAF-acether) in dogs.European journal of pharmacology, , Jan-21, Volume: 86, Issue:3-4, 1983
[Cardio- and hemodynamics of dogs during the development of postischemic shock reaction].Fiziologicheskii zhurnal, , Volume: 35, Issue:4
Role of neutrophil elastase in development of pulmonary vascular injury and septic shock in rats.Shock (Augusta, Ga.), , Volume: 30, Issue:4, 2008
Cyclooxygenase inhibitor blocks rebound response after NO inhalation in an endotoxin model.American journal of physiology. Heart and circulatory physiology, , Volume: 284, Issue:1, 2003
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The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock.Shock (Augusta, Ga.), , Volume: 13, Issue:6, 2000
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Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria.Shock (Augusta, Ga.), , Volume: 12, Issue:2, 1999
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The influence of heat shock protein 70 induction on hemodynamic variables in a porcine model of recurrent endotoxemia.Shock (Augusta, Ga.), , Volume: 7, Issue:5, 1997
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G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, inhibits tumor necrosis factor-alpha biosynthesis.European journal of pharmacology, , Nov-03, Volume: 286, Issue:1, 1995
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Protective effect of Y-20811, a long-lasting thromboxane synthetase inhibitor, on endotoxin shock in rabbits.Thrombosis research, , Feb-15, Volume: 57, Issue:4, 1990
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Complement depletion with Naje haje cobra venom factor limits prostaglandin release and improves visceral perfusion in porcine endotoxic shock.The Journal of trauma, , Volume: 29, Issue:8, 1989
Inhibition of lipoxygenase (LOX) or of cyclooxygenase (COX) improves survival of rats in endotoxin shock.Biomedica biochimica acta, , Volume: 47, Issue:10-11, 1988
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Effect of naloxone and ibuprofen on organ blood flow during endotoxic shock in pig.The American journal of physiology, , Volume: 255, Issue:1 Pt 2, 1988
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The efficacy of dexamethasone and flunixin meglumine in treating endotoxin-induced changes in calves.Veterinary research communications, , Volume: 11, Issue:5, 1987
Leukotriene antagonist FPL 57231 prevents the acute pulmonary effects of Escherichia coli endotoxin in cats.Circulatory shock, , Volume: 21, Issue:2, 1987
The clinical significance of prostaglandins and thromboxane as mediators of septic shock.Klinische Wochenschrift, , Jan-15, Volume: 65, Issue:2, 1987
Efficiency of prostacyclin in rabbit endotoxin shock.Progress in clinical and biological research, , Volume: 236A, 1987
Prostaglandin synthetase inhibition in group B streptococcal shock: hematologic and hemodynamic effects.Pediatric research, , Volume: 20, Issue:9, 1986
The effects of alpha adrenergic blockade on arachidonic acid metabolism and shock sequelae in endotoxemia.Circulatory shock, , Volume: 20, Issue:2, 1986
Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance.Prostaglandins, , Volume: 31, Issue:4, 1986
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Low-dose dopamine preserves renal blood flow in endotoxin shocked dogs treated with ibuprofen.The Journal of surgical research, , Volume: 38, Issue:6, 1985
Elevated plasma 6-keto-prostaglandin F1 alpha in patients in septic shock.Critical care medicine, , Volume: 13, Issue:6, 1985
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Sulindac does not preserve renal prostacyclin synthesis during endotoxemia.Prostaglandins, , Volume: 29, Issue:6, 1985
Metabolic and cardiovascular effects of endotoxin infusion in conscious unrestrained rats: effects of methylprednisolone and BW755C.Circulatory shock, , Volume: 15, Issue:3, 1985
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Prostanoid production by lipopolysaccharide-stimulated Kupffer cells.The Journal of surgical research, , Volume: 38, Issue:5, 1985
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Prostacyclin biosynthesis and hypotension in relation to complement activation in rabbit endotoxic shock.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
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Thromboxane and prostacyclin production during septic shock.Advances in shock research, , Volume: 7, 1982
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Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581.The Journal of pharmacology and experimental therapeutics, , Volume: 222, Issue:2, 1982
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Pacing-induced myocardial ischemia does not affect the endothelial release of coagulant and fibrinolytic factors into the coronary circulation.Clinical cardiology, , Volume: 14, Issue:3, 1991
The role of prostacyclin in the mesenteric traction syndrome during anesthesia for abdominal aortic reconstructive surgery.Annals of surgery, , Volume: 209, Issue:3, 1989
Adenosine cardioprotection study in clinical setting of paroxysmal supraventricular tachycardia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 74, Issue:6, 2006
[Content of endogenous prostanoids in patients with paroxysmal supraventricular disorders of the heart rhythm].Kardiologiia, , Volume: 26, Issue:6, 1986
Adenosine cardioprotection study in clinical setting of paroxysmal supraventricular tachycardia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 74, Issue:6, 2006
[Content of endogenous prostanoids in patients with paroxysmal supraventricular disorders of the heart rhythm].Kardiologiia, , Volume: 26, Issue:6, 1986
In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia.Thrombosis and haemostasis, , Jul-03, Volume: 112, Issue:1, 2014
[The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia].Zhonghua yi xue za zhi, , Jan-26, Volume: 90, Issue:4, 2010
Generation of arachidonic acid metabolites from stimulated whole blood in patients with chronic myeloproliferative disorders.Acta haematologica, , Volume: 85, Issue:2, 1991
Haemodynamic and haematologic effects of Acanthaster planci venom in dogs.Toxicon : official journal of the International Society on Toxinology, , Volume: 32, Issue:10, 1994
Thromboxane A2 accounts for bronchoconstriction but not for platelet sequestration and microvascular albumin exchanges induced by fMLP in the guinea pig lung.The Journal of pharmacology and experimental therapeutics, , Volume: 260, Issue:2, 1992
Evaluation of platelets and hemostasis during hemodialysis with six different membranes.Nephron, , Volume: 59, Issue:4, 1991
Antithrombotic activity of garlic: its inhibition of the synthesis of thromboxane-B2 during infusion of arachidonic acid and collagen in rabbits.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 41, Issue:2, 1990
Increased in vivo biosynthesis of prostacyclin and thromboxane A2 in chronic idiopathic thrombocytopenic purpura.British journal of haematology, , Volume: 72, Issue:3, 1989
Streptococcus pneumoniae-induced alterations in levels of circulating thromboxane and prostacyclin: dissociation from granulocytopenia, thrombocytopenia, and pulmonary leukostasis.The Journal of infectious diseases, , Volume: 153, Issue:1, 1986
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.Thrombosis research, , Jul-15, Volume: 43, Issue:2, 1986
Low-dose PGI2 prevents monocrotaline-induced thromboxane production and lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:2, 1986
Hemodialysis-associated platelet activation and thrombocytopenia.The American journal of medicine, , Volume: 78, Issue:4, 1985
Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep.Circulation research, , Volume: 52, Issue:1, 1983
In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat.Thrombosis research, , Oct-01, Volume: 32, Issue:1, 1983
Contribution of complement activation to the rise in blood levels of 6-oxo-prostaglandin F1 alpha during endotoxin-induced hypotension in rabbits.European journal of pharmacology, , Apr-08, Volume: 79, Issue:1-2, 1982
Thromboxane and prostacyclin production during septic shock.Advances in shock research, , Volume: 7, 1982
Complement activation and blood levels of 6-oxo-prostaglandin F1alpha during endotoxin-induced hypotension in rabbits.Archives internationales de pharmacodynamie et de therapie, , Volume: 249, Issue:2, 1981
Blood levels of 6-oxo-prostaglandin F 1 alpha during endotoxin-induced hypotension in rabbits.European journal of pharmacology, , Apr-11, Volume: 63, Issue:1, 1980
The effects of drugs on the arachidonate cascade in experimentally burned rabbits.The Journal of burn care & rehabilitation, , Volume: 10, Issue:4
[The effects of lupus anticoagulant on pulmonary thromboembolism].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 27, Issue:11, 2004
[Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 27, Issue:5, 2004
Experimental evidence of a potentially increased thrombo-embolic disease risk by domestic electromagnetic field exposure.Bioelectromagnetics, , Volume: 25, Issue:4, 2004
3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.Journal of medicinal chemistry, , Feb-21, Volume: 35, Issue:4, 1992
[Thromboxane, prostacyclin and platelet factor 4 in patients with atrial fibrillation].Klinicheskaia meditsina, , Volume: 69, Issue:7, 1991
Haemostatic factors associated with vascular thrombosis in patients with systemic lupus erythematosus and the lupus anticoagulant.Annals of the rheumatic diseases, , Volume: 50, Issue:8, 1991
Intermittent pneumatic compression in chronic venous insufficiency favorably affects fibrinolytic potential and platelet activation.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, , Volume: 7, Issue:4, 1996
Effect of policosanol on experimental thrombosis models.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 50, Issue:5, 1994
Platelet function and fibrinolytic activity in cervical spinal cord injured patients.Thrombosis research, , Feb-01, Volume: 65, Issue:3, 1992
The changes in prostaglandins after segmental pancreatic transplantation.Transplantation proceedings, , Volume: 23, Issue:1 Pt 2, 1991
Elevated levels of 6-keto-prostaglandin-F1a from a lower extremity during external pneumatic compression.Surgery, gynecology & obstetrics, , Volume: 166, Issue:4, 1988
Thromboxane and prostacyclin formation in patients with deep vein thrombosis.Thrombosis research, , Feb-15, Volume: 45, Issue:4, 1987
Panax Notoginseng Saponins Combined with Dual Antiplatelet Drugs Potentiates Anti-Thrombotic Effect with Alleviated Gastric Injury in A Carotid Artery Thrombosis Rat Model.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, , Volume: 31, Issue:8, 2022
Study on the antithrombotic effect and physiological mechanism of okanin.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, , Volume: 153, 2022
[Anti-platelet aggregation and anti-thrombotic mechanism of Trichosanthis Fructus combined with aspirin based on network pharmacology].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 44, Issue:8, 2019
Vascular Nitric Oxide-Superoxide Balance and Thrombus Formation after Acute Exercise.Medicine and science in sports and exercise, , Volume: 50, Issue:7, 2018
Antithrombotic Effect and Mechanism of Radix Paeoniae Rubra.BioMed research international, , Volume: 2017, 2017
Antithrombotic effect and mechanism of Rubus spp. Blackberry.Food & function, , May-24, Volume: 8, Issue:5, 2017
Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB2/6-keto-PGF1α and blood biochemistry in rat model.BMC veterinary research, , Jun-14, Volume: 12, Issue:1, 2016
The antithrombotic effect of RSNK in blood-stasis model rats.Journal of ethnopharmacology, , Sep-15, Volume: 173, 2015
Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis.Journal of ethnopharmacology, , Feb-27, Volume: 152, Issue:1, 2014
Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats.Chinese journal of integrative medicine, , Volume: 19, Issue:2, 2013
Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.Chemical & pharmaceutical bulletin, , Volume: 61, Issue:2, 2013
[The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia].Zhonghua yi xue za zhi, , Jan-26, Volume: 90, Issue:4, 2010
Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo.Journal of thrombosis and haemostasis : JTH, , Volume: 7, Issue:10, 2009
[Development of virulent heat-evil-induced thrombosis animal model].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 33, Issue:18, 2008
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.World journal of gastroenterology, , Oct-14, Volume: 13, Issue:38, 2007
Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites.Journal of the American College of Nutrition, , Volume: 26, Issue:5, 2007
N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, , Volume: 58, Issue:3, 2007
[Relations of platelet phospholipid fatty acids to thrombotic risk factors in middle-aged and geriatric patients with hyperlipidemia].Zhonghua yi xue za zhi, , Jan-09, Volume: 87, Issue:2, 2007
Experimental arterial thrombosis regulated by androgen and its receptor via modulation of platelet activation.Thrombosis research, , Volume: 121, Issue:1, 2007
[Effect of phenolic alkaloids of Menispermum dauricum on thrombosis and platelet aggregation].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 40, Issue:10, 2005
In vivo endothelial interaction between ACE and COX inhibitors.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 72, Issue:2, 2005
Synergistic effect of D-003 and aspirin on experimental thrombosis models.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 68, Issue:5, 2003
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men.Biomedical and environmental sciences : BES, , Volume: 16, Issue:4, 2003
Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats.Journal of cardiovascular pharmacology, , Volume: 39, Issue:2, 2002
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol.Thrombosis research, , Nov-15, Volume: 100, Issue:4, 2000
Left atrial endocardium and prostacyclin.Prostaglandins & other lipid mediators, , Volume: 57, Issue:2-3, 1999
Effect of oral contraceptives containing 20 and 35 micrograms ethinyl estradiol on urinary prostacyclin and thromboxane metabolite levels in smokers and nonsmokers.Contraception, , Volume: 59, Issue:1, 1999
Platelet-vessel wall interactions with third-generation oral contraceptives: no evidence of detrimental effects.Thrombosis and haemostasis, , Volume: 82, Issue:3, 1999
Influence of cadmium intoxication on thromboresistance of vascular endothelium in rabbits.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, , Volume: 49, Issue:1, 1998
Effects of copper-aspirin complex on platelet aggregation and thrombosis in rabbits and mice.The Journal of pharmacy and pharmacology, , Volume: 50, Issue:11, 1998
PGE1-induced arterial thromboresistance is a vascular property as identified by cross-perfusion technique.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:4, 1997
Evaluation of a polyester collagen-coated heparin bonded vascular graft.The Journal of cardiovascular surgery, , Volume: 38, Issue:1, 1997
The effect of thrombus on the vascular endothelium of arterialized vein grafts.American journal of surgery, , Volume: 172, Issue:2, 1996
Experimental study on microthrombi and myocardial injuries.Microvascular research, , Volume: 51, Issue:1, 1996
Morphological and hemostatic changes in rats with abdominal arterial prosthesis.Thrombosis research, , Apr-01, Volume: 82, Issue:1, 1996
Prostacyclin and thromboxane A2 synthesis are increased in acute lower limb ischaemia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 55, Issue:6, 1996
Procoagulant and prothrombotic responses of human endothelium to indomethacin and endotoxin in vitro. Relevance to non-steroidal anti-inflammatory drug enteropathy.Scandinavian journal of gastroenterology, , Volume: 30, Issue:1, 1995
Experimental studies on preventive effects of API0134 on vessel reocclusion after thrombolysis.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 15, Issue:2, 1995
[Research on plasma TXA2, PGI2 levels, blood stasis syndrome and promoting blood circulation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:11, 1995
[Effects of neferine and its combination with taurine on platelet aggregation and experimental thrombosis in rats].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 30, Issue:7, 1995
Vitamin E deficiency increases serum thromboxane A2, platelet arachidonate and lipid peroxidation in male Sprague-Dawley rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:1, 1994
Effect of policosanol on experimental thrombosis models.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 50, Issue:5, 1994
Thromboxane and prostacyclin synthesis in experimental pancreas transplantation. Changes in parenchymal and vascular prostanoids.Transplantation, , Volume: 56, Issue:6, 1993
A new bioactive molecule for improving vascular graft patency: exploratory trials in dogs.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 15, Issue:4, 1992
Effect of preservation on blood flow and production of prostacyclin and thromboxane A2 in canine segmental pancreatic autografts.Transplantation proceedings, , Volume: 23, Issue:1 Pt 2, 1991
The changes in prostaglandins after segmental pancreatic transplantation.Transplantation proceedings, , Volume: 23, Issue:1 Pt 2, 1991
Haemostatic factors associated with vascular thrombosis in patients with systemic lupus erythematosus and the lupus anticoagulant.Annals of the rheumatic diseases, , Volume: 50, Issue:8, 1991
Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21A, 1991
[Effect of rhyncophylline on platelet aggregation and experimental thrombosis].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 26, Issue:4, 1991
[Changes in plasma TXB2 and 6-keto-PGF1 alpha and left atrial thrombosis in mitral stenosis].Zhonghua xin xue guan bing za zhi, , Volume: 18, Issue:2, 1990
Changes of 6-keto PGF1 alpha concentration in plasma and vessel wall and TxB2 in plasma of whole-body irradiated rats in the early stage of irradiation.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 41, Issue:1, 1990
[Prostacyclin and metabolite assay and the clinical significance].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 48 Suppl, 1990
[Inhibitory effects of new-breviscapine on thrombosis in vivo].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 9, Issue:1, 1989
Arachidonic acid metabolites produced by platelet-depleted human blood monocytes: a possible role in thrombogenesis.American journal of hematology, , Volume: 31, Issue:3, 1989
Interleukin 1 enhances arterial thrombogenicity in vitro.Thrombosis research, , Nov-15, Volume: 56, Issue:4, 1989
Fate of polyester arterial prostheses implanted as thoraco-abdominal by-passes in dogs: haematology, pathology, and biochemistry.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 11, Issue:6, 1988
In vivo production of thromboxane and prostacyclin in patients following total hip arthroplasty.Scandinavian journal of clinical and laboratory investigation, , Volume: 48, Issue:3, 1988
Seeding with endothelial cells derived from the microvessels of the omentum and from the jugular vein: a comparative study.Journal of vascular surgery, , Volume: 7, Issue:5, 1988
Prostacyclin in systemic lupus and anticardiolipin syndrome.Annals of the rheumatic diseases, , Volume: 46, Issue:5, 1987
Inhibition of prostacyclin and thromboxane A2 generation by low-dose aspirin at the site of plug formation in man in vivo.Circulation, , Volume: 75, Issue:5, 1987
Evaluation of platelet function in pregnancy. Comparative studies in non-smokers and smokers.Thrombosis research, , Apr-15, Volume: 46, Issue:2, 1987
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.Thrombosis research, , Jul-15, Volume: 43, Issue:2, 1986
Low dose aspirin does not prevent fibrinolytic response to venous occlusion.Biochemical pharmacology, , Sep-15, Volume: 35, Issue:18, 1986
Potentiation of the inhibitory effect of a thromboxane A2 antagonist (L-640,035) on arterial thrombosis formation in rabbit by the angiotensin converting enzyme inhibitor enalapril.European journal of pharmacology, , Apr-16, Volume: 110, Issue:3, 1985
Platelet survival and function in rats with enhanced thrombotic tendency.Thrombosis and haemostasis, , Dec-17, Volume: 54, Issue:4, 1985
The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis.Thrombosis research, , Feb-01, Volume: 37, Issue:3, 1985
[Pathogenetic importance of prostacyclin in atherosclerosis].Terapevticheskii arkhiv, , Volume: 57, Issue:9, 1985
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Thromboxane production in umbilical vein grafts.Thrombosis research, , Feb-01, Volume: 33, Issue:3, 1984
The antithrombotic effect of aspirin and dipyridamole in relation to prostaglandin synthesis.Thrombosis research, , May-15, Volume: 30, Issue:4, 1983
Sensitivity of rabbit platelet and aortic cyclooxygenase to inhibition by aspirin.Prostaglandins, leukotrienes, and medicine, , Volume: 12, Issue:3, 1983
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01).British journal of clinical pharmacology, , Volume: 15 Suppl 1, 1983
The antithrombotic nature of vascular prosthetic pseudointima.Surgery, , Volume: 91, Issue:1, 1982
The effect of consuming meat enriched in walnut paste on platelet aggregation and thrombogenesis varies in volunteers with different apolipoprotein A4 genotype.Nutricion hospitalaria, , Volume: 25, Issue:5
Effect of aspirin and salicylate on platelet-vessel wall interactions in rabbits.Arteriosclerosis (Dallas, Tex.), , Volume: 4, Issue:4
Delayed thromboxane or tumor necrosis factor-alpha, but not leukotriene inhibition, attenuates prolonged pulmonary hypertension in endotoxemia.The American journal of the medical sciences, , Volume: 310, Issue:3, 1995
Effect of endotoxin on hypoxic pulmonary vasoconstriction--the role of prostaglandins and leukotrienes.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:1, 1992
Low dose flunixin meglumine: effects on eicosanoid production and clinical signs induced by experimental endotoxaemia in horses.Equine veterinary journal, , Volume: 19, Issue:3, 1987
Dose-dependent effects of a pyridoquinazoline thromboxane synthetase inhibitor on arachidonic acid metabolites and hemodynamics during E. coli endotoxemia in anesthetized sheep.Prostaglandins, , Volume: 33, Issue:6, 1987
Placental prostacyclin production in normal and toxemic pregnancies.American journal of obstetrics and gynecology, , Jan-01, Volume: 151, Issue:1, 1985
Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats.Canadian journal of physiology and pharmacology, , Volume: 83, Issue:6, 2005
Increased production of prostacyclin after injury to the microvasculature in uraemic patients.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, , Mar-21, Volume: 81, Issue:6, 1992
[The level of thromboxane A2 and prostacyclin in patients with chronic kidney failure undergoing hemodialysis].Terapevticheskii arkhiv, , Volume: 63, Issue:6, 1991
Renal prostacyclin influences renal function in non-azotemic cirrhotic patients treated with furosemide.Journal of hepatology, , Volume: 12, Issue:2, 1991
[Measurement of urinary TXB2, 6-keto-PGF1 alpha by radioimmunoassay and its clinical significance].Zhonghua nei ke za zhi, , Volume: 26, Issue:12, 1987
Effects of blood-dialyser interaction on prostaglandins in uraemic patients and in healthy man.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, , Volume: 2, Issue:6, 1987
Renal handling of urea in subjects with persistent azotemia and normal renal function.Kidney international, , Volume: 32, Issue:5, 1987
Partial isolation and function of the prostacyclin regulating plasma factor.Clinical science (London, England : 1979), , Volume: 69, Issue:4, 1985
Prostacyclin and thromboxane in chronic uremia: effect of hemodialysis.Clinical nephrology, , Volume: 18, Issue:2, 1982
Enhanced 6-oxo-PGF1 alpha levels in plasma during hemodialysis.Prostaglandins and medicine, , Volume: 5, Issue:6, 1980
Uremic levels of oxalic acid suppress replication and migration of human endothelial cells.Arteriosclerosis (Dallas, Tex.), , Volume: 10, Issue:2
Abnormal uterus with polycysts, accumulation of uterine prostaglandins, and reduced fertility in mice heterozygous for acyl-CoA synthetase 4 deficiency.Biochemical and biophysical research communications, , Jun-22, Volume: 284, Issue:4, 2001
Intrauterine infection and the effects of inflammatory mediators on prostaglandin production by myometrial cells from pregnant women.American journal of obstetrics and gynecology, , Volume: 174, Issue:2, 1996
Eicosanoids production in endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:4, 1992
Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma.Cancer research, , Aug-15, Volume: 51, Issue:16, 1991
Prostacyclin and thromboxane synthesis by endometrial cancer and leiomyomas.Prostaglandins, , Volume: 39, Issue:3, 1990
Prostaglandin and leukotriene concentration of the peritoneal fluid of endometriosis and other gynecologic disorders in the secretory phase.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Prostaglandin production by human myometrium, uterine cervix and leiomyoma.Prostaglandins, leukotrienes, and medicine, , Volume: 29, Issue:1, 1987
Plasma prostaglandin levels in patients with gynecologic malignancies and its fluctuations during chemotherapeutically-induced gastrointestinal toxicity.Japanese journal of clinical oncology, , Volume: 17, Issue:3, 1987
Peritoneal fluid 6-keto prostaglandin F1 alpha levels in women with endometriosis.American journal of obstetrics and gynecology, , Aug-01, Volume: 152, Issue:7 Pt 1, 1985
Leiomyomas release prostaglandins.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:1, 1985
Thromboxane A2 and prostacyclin levels in molar pregnancy.British journal of obstetrics and gynaecology, , Volume: 91, Issue:9, 1984
Cyclic nucleotides and production of prostanoids in human varicose veins.Journal of vascular surgery, , Volume: 30, Issue:5, 1999
[Correlation between serotonin and prostaglandins in peritoneal fluid collected from patients with pelvic congestion].Zhonghua fu chan ke za zhi, , Volume: 28, Issue:6, 1993
Increased prostacyclin and thromboxane A2 formation in human varicose veins.The Journal of surgical research, , Volume: 49, Issue:3, 1990
Differential salicylate-aspirin interaction on vascular prostacyclin and platelet thromboxane synthesis in patients undergoing saphenectomy.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 180, Issue:3, 1985
8-Epi-PGF2alpha and 6-oxo-PGF1alpha in human (varicose) veins: influence of age, sex, and risk factors.Angiology, , Volume: 54, Issue:3
Role of neutrophil elastase in development of pulmonary vascular injury and septic shock in rats.Shock (Augusta, Ga.), , Volume: 30, Issue:4, 2008
Oral eicosapentaenoic acid for complications of bone marrow transplantation.Bone marrow transplantation, , Volume: 28, Issue:8, 2001
An imbalance in plasma prostanoids in patients with Raynaud's phenomenon and pulmonary vasospasm.The European respiratory journal, , Volume: 13, Issue:1, 1999
Antithrombin prevents endotoxin-induced pulmonary vascular injury by inhibiting leukocyte activation.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, , Volume: 9 Suppl 2, 1998
Sickle cell vaso-occlusive crisis is associated with abnormalities in the ratio of vasoconstrictor to vasodilator prostanoids.Pediatric research, , Volume: 38, Issue:1, 1995
The change of urinary 11-dehydro-thromboxane B2 and 2,3-dinor-6-keto-prostaglandin F1 alpha in arteriogenic impotence.The Journal of urology, , Volume: 148, Issue:2 Pt 1, 1992
Decreased prostacyclin levels in sickle-cell disease.Pediatric hematology and oncology, , Volume: 6, Issue:1, 1989
Measurements of 6-keto-prostaglandin F1 alpha and thromboxane B2 in bleeding time blood: relation to bleeding and vascular disorders?Canadian journal of physiology and pharmacology, , Volume: 67, Issue:8, 1989
[Effect of coenzyme A (COA) on the 6-keto-prostaglandin F1 alpha content of the aorta of rats made diabetic with streptozotocin. Potential mechanism of action of its favorable effect on microcirculatory disorders in man].Journal des maladies vasculaires, , Volume: 13, Issue:3, 1988
Prostacyclin production in vascular endothelium of patients with Blackfoot disease.Advances in experimental medicine and biology, , Volume: 242, 1988
Prostacyclin in the circulation of patients with vascular disorders undergoing surgery.Clinical science (London, England : 1979), , Volume: 71, Issue:6, 1986
[Prostaglandins and applications in clinical biology].Annales de biologie clinique, , Volume: 43, Issue:4, 1985
Relation of arachidonate metabolites to abnormal control of the pulmonary circulation in a child.The American review of respiratory disease, , Volume: 131, Issue:1, 1985
[Angiopathy caused by vibrating tools: cold test and prostaglandin balance].La Medicina del lavoro, , Volume: 81, Issue:1
[Reduction of incidence of ischemia-reperfusion induced ventricular fibrillation by captopril].Sheng li xue bao : [Acta physiologica Sinica], , Volume: 47, Issue:6, 1995
[Participation of the prostacyclin-thromboxane system in the mechanisms of prevention of arrhythmia caused by occlusion of the coronary artery in adapted rats].Biulleten' eksperimental'noi biologii i meditsiny, , Volume: 111, Issue:1, 1991
Effects of a thromboxane A2 synthetase inhibitor on ventricular fibrillation threshold during coronary artery occlusion and reperfusion.Japanese heart journal, , Volume: 31, Issue:1, 1990
Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion.American heart journal, , Volume: 115, Issue:3, 1988
Further evidence that thromboxane exacerbates arrhythmias: effects of UK38485 during coronary artery occlusion and reperfusion in anaesthetized greyhounds.Journal of molecular and cellular cardiology, , Volume: 16, Issue:7, 1984
Protective effect of a novel thromboxane synthetase inhibitor, CV-4151, on myocardial damage due to coronary occlusion and reperfusion in the hearts of anesthetized dogs.Journal of cardiovascular pharmacology, , Volume: 8, Issue:4
Effect of Ca-antagonists, beta-blockers and antioxidant during reperfusion period.Bratislavske lekarske listy, , Volume: 92, Issue:3-4
Plasma prostaglandin levels in patients with gynecologic malignancies and its fluctuations during chemotherapeutically-induced gastrointestinal toxicity.Japanese journal of clinical oncology, , Volume: 17, Issue:3, 1987
Effect of ionizing radiation on prostaglandins and gastric secretion in rhesus monkeys.Radiation research, , Volume: 110, Issue:2, 1987
Plasma 6-keto-prostaglandin F1 alpha in disorders involving hypokalemia.Prostaglandins, leukotrienes, and medicine, , Volume: 9, Issue:5, 1982
Early inflammatory response correlates with the severity of injury.Critical care medicine, , Volume: 24, Issue:7, 1996
Time course of trauma induced alterations of plasma prostanoid levels in intensive care patients.Progress in clinical and biological research, , Volume: 301, 1989
Measurement of 6-keto-PGF1 alpha and thromboxane B2 levels in critically ill surgical patients.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 33, Issue:2, 1988
Thromboxane and prostacyclin release in adult respiratory distress syndrome.Intensive care medicine, , Volume: 13, Issue:3, 1987
The effect of nifedipine, nimodipine and nisoldipine on agonist- and trauma-stimulated vascular prostacyclin synthesis in vitro.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 332, Issue:1, 1986
Biochemical pathways of acute lung injury.Bulletin europeen de physiopathologie respiratoire, , Volume: 21, Issue:3
Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial.BMC surgery, , Aug-11, Volume: 17, Issue:1, 2017
Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice.Biochemical and biophysical research communications, , Jul-18, Volume: 372, Issue:1, 2008
Cyclooxygenase-2-Derived Prostaglandins Mediate Cerebral Microcirculation in a Juvenile Ischemic Rat Model.Stroke, , Volume: 47, Issue:12, 2016
[Effects of paeoniflorin on cerebral blood flow and the balance of PGI2/TXA2 of rats with focal cerebral ischemia-reperfusion injury].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 49, Issue:1, 2014
Chemical composition of hepatic lipids mediates reperfusion injury of the macrosteatotic mouse liver through thromboxane A(2).Journal of hepatology, , Volume: 55, Issue:6, 2011
Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain.The American journal of Chinese medicine, , Volume: 39, Issue:2, 2011
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Atrial natriuretic peptide reduces ischemia/reperfusion-induced spinal cord injury in rats by enhancing sensory neuron activation.The Journal of pharmacology and experimental therapeutics, , Volume: 322, Issue:2, 2007
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Expression of interleukin-18 in a rat model of deep vein thrombosis.The Journal of cardiovascular surgery, , Volume: 53, Issue:5, 2012
D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 67, Issue:1, 2002
Increased thromboxane production in women with a history of venous thromboembolic event: effect of heparins.British journal of haematology, , Volume: 114, Issue:3, 2001
Dissecting Xuesaitong's mechanisms on preventing stroke based on the microarray and connectivity map.Molecular bioSystems, , Volume: 11, Issue:11, 2015
Association of cyclooxygenase-2 genetic variant with cardiovascular disease.European heart journal, , Sep-01, Volume: 35, Issue:33, 2014
Diagnostic biomarkers of essential arterial hypertension: the value of prostacyclin, nitric oxide, oxidized-LDL, and peroxide measurements.International heart journal, , Volume: 50, Issue:3, 2009
The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation.Stroke, , Volume: 31, Issue:6, 2000
[Dynamics of violations of intravascular platelet activity in rats during the formation of metabolic syndrome using fructose models].Voprosy pitaniia, , Volume: 85, Issue:1, 2016
Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome.The British journal of nutrition, , Jul-14, Volume: 110, Issue:1, 2013
[Disturbed synthesis of eicosanoids in patients with metabolic syndrome].Klinicheskaia meditsina, , Volume: 88, Issue:3, 2010
Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats.Clinical and experimental hypertension (New York, N.Y. : 1993), , Volume: 32, Issue:7, 2010
Oral treatment and in vitro incubation with fructose modify vascular prostanoid production in the rat.Autonomic & autacoid pharmacology, , Volume: 26, Issue:1, 2006
Prevention of atherosclerosis by Yindan Xinnaotong capsule combined with swimming in rats.BMC complementary and alternative medicine, , Apr-08, Volume: 15, 2015
Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.Chemical & pharmaceutical bulletin, , Volume: 61, Issue:2, 2013
Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats.Journal of ethnopharmacology, , Jul-09, Volume: 148, Issue:2, 2013
Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.The Journal of clinical investigation, , Volume: 122, Issue:4, 2012
Cyclo-oxygenase-2 -765G > C promoter variants are associated with lower carotid plaque echogenicity in Japanese.Cerebrovascular diseases (Basel, Switzerland), , Volume: 27, Issue:1, 2009
Diagnostic biomarkers of essential arterial hypertension: the value of prostacyclin, nitric oxide, oxidized-LDL, and peroxide measurements.International heart journal, , Volume: 50, Issue:3, 2009
Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits.American journal of physiology. Heart and circulatory physiology, , Volume: 297, Issue:5, 2009
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.Circulation research, , Feb-27, Volume: 104, Issue:4, 2009
Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor.British journal of pharmacology, , Volume: 156, Issue:5, 2009
Protective effects of Danshensu on liver injury induced by omethoate in rats.Toxicology mechanisms and methods, , Volume: 20, Issue:8, 2010
Prostanoids and free radicals in Cl4C-induced hepatotoxicity in rats: effect of astilbin.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:4, 1997
Arachidonic acid metabolism in galactosamine/endotoxin induced acute liver injury in rats.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 14, Issue:3, 1994
[Effects of magnesium lithospermate B on D-galactosamine induced rat liver injury].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:6, 1993
Effects of D-galactosamine-induced acute liver injury on mortality and pulmonary responses to Escherichia coli lipopolysaccharide. Modulation by arachidonic acid metabolites.The American review of respiratory disease, , Volume: 141, Issue:5 Pt 1, 1990
The urinary levels of prostanoid metabolites predict acute kidney injury in heterogeneous adult Japanese ICU patients: a prospective observational study.Clinical and experimental nephrology, , Volume: 19, Issue:6, 2015
Using inflammatory and oxidative biomarkers in urine to predict early acute kidney injury in patients undergoing liver transplantation.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, , Volume: 19, Issue:5, 2014
Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice.American journal of physiology. Renal physiology, , Volume: 293, Issue:4, 2007
[Effect of glycerol-induced acute renal failure in rabbit with Ligusticum wallichii on thromboxane B2, 6-keto-prostaglandin F1 alpha/thromboxane B2].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:9, 1993
A thromboxane A2 synthase inhibitor, DP-1904, prevents rat renal injury.European journal of pharmacology, , Feb-14, Volume: 193, Issue:3, 1991
Partial protection against acute renal failure by Efamol.Progress in clinical and biological research, , Volume: 301, 1989
Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited.Annals of surgery, , Volume: 209, Issue:2, 1989
The role of prostaglandin and thromboxane synthesis by the glomeruli in the development of acute renal failure.Eicosanoids, , Volume: 2, Issue:3, 1989
Alterations in rabbit renal microvascular prostanoid synthesis in acute renal failure.The American journal of physiology, , Volume: 254, Issue:5 Pt 2, 1988
Inhibition of thromboxane (Tx) synthesis by free radical scavengers.The Journal of trauma, , Volume: 28, Issue:4, 1988
Vasoactive hormones in the renal response to systemic sepsis.American journal of kidney diseases : the official journal of the National Kidney Foundation, , Volume: 11, Issue:1, 1988
The clinical significance of prostaglandins and thromboxane as mediators of septic shock.Klinische Wochenschrift, , Jan-15, Volume: 65, Issue:2, 1987
Renal function in fulminant hepatic failure: haemodynamics and renal prostaglandins.Gut, , Volume: 28, Issue:12, 1987
Selective inhibition of thromboxane synthesis partially protected while inhibition of angiotensin II formation did not protect rats against acute renal failure induced with glycerol.Prostaglandins, leukotrienes, and medicine, , Volume: 21, Issue:1, 1986
Renal prostaglandins in cirrhosis of the liver.Clinical science (London, England : 1979), , Volume: 70, Issue:5, 1986
Selective inhibition of thromboxane synthesis in glycerol-induced acute renal failure.American journal of kidney diseases : the official journal of the National Kidney Foundation, , Volume: 8, Issue:1, 1986
Urinary excretion of 6-keto-prostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 in cirrhosis with ascites. Relationship to functional renal failure (hepatorenal syndrome).Journal of hepatology, , Volume: 3, Issue:1, 1986
Altered renal and platelet arachidonic acid metabolism in cirrhosis.Gastroenterology, , Volume: 90, Issue:2, 1986
Prostacyclin and thromboxane A2 moderate postischemic renal failure.Surgery, , Volume: 98, Issue:2, 1985
Therapeutic trial of thromboxane synthesis inhibition in the hepatorenal syndrome.Gastroenterology, , Volume: 87, Issue:6, 1984
Prostaglandins in vascular tone in experimental obstructive nephropathy.Kidney international, , Volume: 19, Issue:6, 1981
Relation between arterial hypoxemia and plasma eicosanoids in neonates with congenital diaphragmatic hernia.The Journal of surgical research, , Volume: 53, Issue:6, 1992
Congenital diaphragmatic hernia: impact of prostanoids in the perioperative period.Archives of disease in childhood, , Volume: 65, Issue:9, 1990
Extracorporeal membrane oxygenation and congenital diaphragmatic hernia: modification of the pulmonary vasoactive profile.Journal of pediatric surgery, , Volume: 20, Issue:6, 1985
Congenital diaphragmatic hernia: association between pulmonary vascular resistance and plasma thromboxane concentrations.Archives of disease in childhood, , Volume: 59, Issue:2, 1984
Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.Respiratory research, , 08-31, Volume: 17, Issue:1, 2016
AAV-PGIS gene transfer improves hypoxia-induced pulmonary hypertension in mice.Biochemical and biophysical research communications, , Nov-23, Volume: 363, Issue:3, 2007
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.Hypertension (Dallas, Tex. : 1979), , Volume: 50, Issue:3, 2007
Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats.Human gene therapy, , Volume: 15, Issue:12, 2004
Delta-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits.American journal of physiology. Heart and circulatory physiology, , Volume: 283, Issue:5, 2002
Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits.Proceedings of the National Academy of Sciences of the United States of America, , Aug-29, Volume: 97, Issue:18, 2000
Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:2, 1997
Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine.Pharmacology, , Volume: 53, Issue:2, 1996
Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 112, Issue:5, 2012
Signs of platelet activation, but not lipid peroxidation, in fetal blood associated with functional and structural umbilicoplacental lesions in pregnancies complicated by impaired glucose metabolism.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, , Volume: 12, Issue:3, 2002
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Prostanoid production in the umbilicoplacental arterial tree relative to impaired glucose tolerance.Early human development, , Jan-09, Volume: 50, Issue:2, 1998
Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.Respiratory research, , 08-31, Volume: 17, Issue:1, 2016
Trans-10,cis-12-conjugated linoleic acid worsens renal pathology and alters cyclooxygenase derived oxylipins in obesity-associated nephropathy.The Journal of nutritional biochemistry, , Volume: 26, Issue:2, 2015
Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up.Journal of the neurological sciences, , Dec-15, Volume: 287, Issue:1-2, 2009
Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease.Experimental biology and medicine (Maywood, N.J.), , Volume: 234, Issue:7, 2009
[High-protein diet and high-grade proteinuria aggravate the progression of chronic renal failure in rats].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 5, Issue:3, 2007
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
Effects of cicletanine on the progression of renal failure in 5/6 nephrectomized hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 26, Issue:3, 1999
Progression of carotid atherosclerosis and the role of endothelin in diabetic patients.Research communications in molecular pathology and pharmacology, , Volume: 108, Issue:1-2
Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.Respiratory research, , 08-31, Volume: 17, Issue:1, 2016
Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats.Respiratory research, , 08-04, Volume: 17, Issue:1, 2016
Oral eicosapentaenoic acid for complications of bone marrow transplantation.Bone marrow transplantation, , Volume: 28, Issue:8, 2001
Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns.Burns : journal of the International Society for Burn Injuries, , Volume: 24, Issue:8, 1998
Evaluation of enzyme-linked immunosorbent assays for quantitation of eicosanoid mediators of sepsis syndrome.Shock (Augusta, Ga.), , Volume: 6, Issue:2, 1996
Perivascular adipose tissue contributes to lethal sepsis-induced vasoplegia in rats.European journal of pharmacology, , Nov-15, Volume: 863, 2019
Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis.Pharmacological research, , Volume: 48, Issue:1, 2003
Effects of long-term hemofiltration on circulating mediators and superoxide production during continuous endotoxin administration.The Journal of trauma, , Volume: 46, Issue:5, 1999
Alterations in hepatic gluconeogenesis, prostanoid, and intracellular calcium during sepsis.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, , Volume: 6, Issue:6, 1999
Effects of various doses of antithrombin III on endotoxin-induced endothelial cell injury and coagulation abnormalities in rats.Thrombosis research, , Mar-01, Volume: 89, Issue:5, 1998
Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns.Burns : journal of the International Society for Burn Injuries, , Volume: 24, Issue:8, 1998
Hepatocellular dysfunction occurs earlier than the onset of hyperdynamic circulation during sepsis.Shock (Augusta, Ga.), , Volume: 3, Issue:1, 1995
Delayed thromboxane or tumor necrosis factor-alpha, but not leukotriene inhibition, attenuates prolonged pulmonary hypertension in endotoxemia.The American journal of the medical sciences, , Volume: 310, Issue:3, 1995
PAF acetylhydrolase and arachidonic acid metabolite levels in patients with sepsis.Research communications in chemical pathology and pharmacology, , Volume: 84, Issue:3, 1994
Relationship between leukotriene B4 and prostaglandin I2 in patients with sepsis.Research communications in molecular pathology and pharmacology, , Volume: 86, Issue:1, 1994
Comparison of the early dynamics of systemic prostacyclin release after administration of tumor necrosis factor and endotoxin to healthy humans.The Journal of infectious diseases, , Volume: 164, Issue:3, 1991
Effects of D-galactosamine-induced acute liver injury on mortality and pulmonary responses to Escherichia coli lipopolysaccharide. Modulation by arachidonic acid metabolites.The American review of respiratory disease, , Volume: 141, Issue:5 Pt 1, 1990
Eicosanoids and the hemodynamic course of live Escherichia coli-induced sepsis in baboons.Circulatory shock, , Volume: 29, Issue:3, 1989
Measurement of 6-keto-PGF1 alpha and thromboxane B2 levels in critically ill surgical patients.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 33, Issue:2, 1988
The role of leukotrienes in the late hemodynamic manifestations of group B streptococcal sepsis in piglets.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 33, Issue:3, 1988
Thromboxane and prostacyclin release in adult respiratory distress syndrome.Intensive care medicine, , Volume: 13, Issue:3, 1987
Effects of a leukotriene antagonist on the early hemodynamic manifestations of group B streptococcal sepsis in piglets.Pediatric research, , Volume: 20, Issue:10, 1986
Effects of repeated endotoxin injections on prostanoids, hemodynamics, endothelial cells, and survival in ponies.Circulatory shock, , Volume: 16, Issue:3, 1985
Plasma levels of 6-keto PGF1 alpha but not TxB2 increase in rats with peritonitis due to cecal ligation.Circulatory shock, , Volume: 16, Issue:3, 1985
Thromboxane, prostacyclin, and the hemodynamic effects of graded bacteremic shock.Circulatory shock, , Volume: 16, Issue:4, 1985
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis.Annals of surgery, , Volume: 200, Issue:5, 1984
Effects of a fish oil diet on pigs' cardiopulmonary response to bacteremia.JPEN. Journal of parenteral and enteral nutrition, , Volume: 15, Issue:2
[Effects of electro-acupuncture at Zusanli point on gastric and intestinal blood flow in rats with acute necrotizing pancreatitis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, , Volume: 44, Issue:6, 2013
Changes in somatostatin receptor expression of the pancreas and effectiveness of octreotide in rats with acute necrotizing pancreatitis.Chinese journal of digestive diseases, , Volume: 5, Issue:1, 2004
The role of inflammatory mediators in severe acute pancreatitis and regulation of glucocorticoids.Hepatobiliary & pancreatic diseases international : HBPD INT, , Volume: 2, Issue:3, 2003
The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats.Pancreas, , Volume: 17, Issue:2, 1998
[Effects and mechanism of emodin and sandostatin on pancreatic ischemia in acute haemorrhagic necrotizing pancreatitis].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 17, Issue:6, 1997
Systemic prostacyclin and thromboxane production in obstructive sleep apnea.Advances in medical sciences, , Volume: 61, Issue:1, 2016
Modulation of inflammatory and hemostatic markers in obstructive sleep apnea patients treated with mandibular advancement splints: a parallel, controlled trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, , Mar-15, Volume: 10, Issue:3, 2014
[Detection of thromboxane B2, 6-keto-prostaglandin F1alpha and anticardiolipin antibody in patients with obstructive sleep apnea-hypopnea syndrome].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 27, Issue:5, 2004
Effect of valsartan and captopril in rabbit carotid injury. Possible involvement of bradykinin in the antiproliferative action of the renin-angiotensin blockade.Journal of the renin-angiotensin-aldosterone system : JRAAS, , Volume: 2, Issue:1, 2001
Prostacyclin synthase gene transfer accelerates reendothelialization and inhibits neointimal formation in rat carotid arteries after balloon injury.Arteriosclerosis, thrombosis, and vascular biology, , Volume: 19, Issue:3, 1999
Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats.Stroke, , Volume: 30, Issue:2, 1999
Dissecting Xuesaitong's mechanisms on preventing stroke based on the microarray and connectivity map.Molecular bioSystems, , Volume: 11, Issue:11, 2015
[Effects of paeoniflorin on cerebral blood flow and the balance of PGI2/TXA2 of rats with focal cerebral ischemia-reperfusion injury].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 49, Issue:1, 2014
Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain.The American journal of Chinese medicine, , Volume: 39, Issue:2, 2011
Cotinine inhibits TLR4/NF-κB signaling pathway and improves deep vein thrombosis in rats.Bioscience reports, , 06-26, Volume: 40, Issue:6, 2020
Effects of Cydonia oblonga Miller extracts on blood hemostasis, coagulation and fibrinolysis in mice, and experimental thrombosis in rats.Journal of ethnopharmacology, , May-28, Volume: 154, Issue:1, 2014
Effects of danshensu on platelet aggregation and thrombosis: in vivo arteriovenous shunt and venous thrombosis models in rats.PloS one, , Volume: 9, Issue:11, 2014
Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats.Chinese journal of integrative medicine, , Volume: 19, Issue:2, 2013
Expression of interleukin-18 in a rat model of deep vein thrombosis.The Journal of cardiovascular surgery, , Volume: 53, Issue:5, 2012
D-003, a potential antithrombotic compound isolated from sugar cane wax with effects on arachidonic acid metabolites.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 67, Issue:1, 2002
Increased thromboxane production in women with a history of venous thromboembolic event: effect of heparins.British journal of haematology, , Volume: 114, Issue:3, 2001
Dissecting Xuesaitong's mechanisms on preventing stroke based on the microarray and connectivity map.Molecular bioSystems, , Volume: 11, Issue:11, 2015
Association of cyclooxygenase-2 genetic variant with cardiovascular disease.European heart journal, , Sep-01, Volume: 35, Issue:33, 2014
Diagnostic biomarkers of essential arterial hypertension: the value of prostacyclin, nitric oxide, oxidized-LDL, and peroxide measurements.International heart journal, , Volume: 50, Issue:3, 2009
The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation.Stroke, , Volume: 31, Issue:6, 2000
[Dynamics of violations of intravascular platelet activity in rats during the formation of metabolic syndrome using fructose models].Voprosy pitaniia, , Volume: 85, Issue:1, 2016
Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome.The British journal of nutrition, , Jul-14, Volume: 110, Issue:1, 2013
Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats.Clinical and experimental hypertension (New York, N.Y. : 1993), , Volume: 32, Issue:7, 2010
[Disturbed synthesis of eicosanoids in patients with metabolic syndrome].Klinicheskaia meditsina, , Volume: 88, Issue:3, 2010
Oral treatment and in vitro incubation with fructose modify vascular prostanoid production in the rat.Autonomic & autacoid pharmacology, , Volume: 26, Issue:1, 2006
Vasoconstrictor role of cyclooxygenase-1-mediated prostacyclin synthesis in non-insulin-dependent diabetic mice induced by high-fat diet and streptozotocin.American journal of physiology. Heart and circulatory physiology, , Aug-01, Volume: 307, Issue:3, 2014
Cyclo-oxygenase-2 -765G > C promoter variants are associated with lower carotid plaque echogenicity in Japanese.Cerebrovascular diseases (Basel, Switzerland), , Volume: 27, Issue:1, 2009
The change of penile blood thromboxane B2 and prostacyclin after intracavernous injection of vasoactive drugs for the treatment of arteriogenic impotence.Proceedings of the National Science Council, Republic of China. Part B, Life sciences, , Volume: 18, Issue:1, 1994
Prevention of atherosclerosis by Yindan Xinnaotong capsule combined with swimming in rats.BMC complementary and alternative medicine, , Apr-08, Volume: 15, 2015
Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.Chemical & pharmaceutical bulletin, , Volume: 61, Issue:2, 2013
Effects of an aqueous extract of Crataegus pinnatifida Bge. var. major N.E.Br. fruit on experimental atherosclerosis in rats.Journal of ethnopharmacology, , Jul-09, Volume: 148, Issue:2, 2013
Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.The Journal of clinical investigation, , Volume: 122, Issue:4, 2012
Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor.British journal of pharmacology, , Volume: 156, Issue:5, 2009
Cyclo-oxygenase-2 -765G > C promoter variants are associated with lower carotid plaque echogenicity in Japanese.Cerebrovascular diseases (Basel, Switzerland), , Volume: 27, Issue:1, 2009
Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits.American journal of physiology. Heart and circulatory physiology, , Volume: 297, Issue:5, 2009
Diagnostic biomarkers of essential arterial hypertension: the value of prostacyclin, nitric oxide, oxidized-LDL, and peroxide measurements.International heart journal, , Volume: 50, Issue:3, 2009
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.Circulation research, , Feb-27, Volume: 104, Issue:4, 2009
Prostanoids: early mediators in the secondary injury that develops after unilateral pulmonary contusion.The Journal of trauma, , Volume: 46, Issue:5, 1999
Constriction and dilatation of pulmonary arterial ring by hydrogen peroxide--importance of prostanoids.Advances in experimental medicine and biology, , Volume: 361, 1994
Effects of recombinant human superoxide dismutase on tumor necrosis factor-induced lung injury in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:6, 1993
Airway acid injury following smoke inhalation.Progress in clinical and biological research, , Volume: 264, 1988
The pulmonary lesion of smoke inhalation in an ovine model.Circulatory shock, , Volume: 18, Issue:4, 1986
Low-dose PGI2 prevents monocrotaline-induced thromboxane production and lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:2, 1986
Role of subcutaneous tissue endotoxin in the production of prostanoid-induced lung injury: comparison with intravenous endotoxin response.Circulatory shock, , Volume: 17, Issue:2, 1985
Biochemical pathways of acute lung injury.Bulletin europeen de physiopathologie respiratoire, , Volume: 21, Issue:3
Protective effects of Danshensu on liver injury induced by omethoate in rats.Toxicology mechanisms and methods, , Volume: 20, Issue:8, 2010
Prostanoids and free radicals in Cl4C-induced hepatotoxicity in rats: effect of astilbin.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:4, 1997
Arachidonic acid metabolism in galactosamine/endotoxin induced acute liver injury in rats.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 14, Issue:3, 1994
[Effects of magnesium lithospermate B on D-galactosamine induced rat liver injury].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:6, 1993
Effects of D-galactosamine-induced acute liver injury on mortality and pulmonary responses to Escherichia coli lipopolysaccharide. Modulation by arachidonic acid metabolites.The American review of respiratory disease, , Volume: 141, Issue:5 Pt 1, 1990
The urinary levels of prostanoid metabolites predict acute kidney injury in heterogeneous adult Japanese ICU patients: a prospective observational study.Clinical and experimental nephrology, , Volume: 19, Issue:6, 2015
Using inflammatory and oxidative biomarkers in urine to predict early acute kidney injury in patients undergoing liver transplantation.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, , Volume: 19, Issue:5, 2014
Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice.American journal of physiology. Renal physiology, , Volume: 293, Issue:4, 2007
[Effect of glycerol-induced acute renal failure in rabbit with Ligusticum wallichii on thromboxane B2, 6-keto-prostaglandin F1 alpha/thromboxane B2].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:9, 1993
A thromboxane A2 synthase inhibitor, DP-1904, prevents rat renal injury.European journal of pharmacology, , Feb-14, Volume: 193, Issue:3, 1991
The role of prostaglandin and thromboxane synthesis by the glomeruli in the development of acute renal failure.Eicosanoids, , Volume: 2, Issue:3, 1989
Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited.Annals of surgery, , Volume: 209, Issue:2, 1989
Partial protection against acute renal failure by Efamol.Progress in clinical and biological research, , Volume: 301, 1989
Vasoactive hormones in the renal response to systemic sepsis.American journal of kidney diseases : the official journal of the National Kidney Foundation, , Volume: 11, Issue:1, 1988
Alterations in rabbit renal microvascular prostanoid synthesis in acute renal failure.The American journal of physiology, , Volume: 254, Issue:5 Pt 2, 1988
Inhibition of thromboxane (Tx) synthesis by free radical scavengers.The Journal of trauma, , Volume: 28, Issue:4, 1988
The clinical significance of prostaglandins and thromboxane as mediators of septic shock.Klinische Wochenschrift, , Jan-15, Volume: 65, Issue:2, 1987
Renal function in fulminant hepatic failure: haemodynamics and renal prostaglandins.Gut, , Volume: 28, Issue:12, 1987
Selective inhibition of thromboxane synthesis in glycerol-induced acute renal failure.American journal of kidney diseases : the official journal of the National Kidney Foundation, , Volume: 8, Issue:1, 1986
Altered renal and platelet arachidonic acid metabolism in cirrhosis.Gastroenterology, , Volume: 90, Issue:2, 1986
Urinary excretion of 6-keto-prostaglandin F1 alpha, thromboxane B2 and prostaglandin E2 in cirrhosis with ascites. Relationship to functional renal failure (hepatorenal syndrome).Journal of hepatology, , Volume: 3, Issue:1, 1986
Renal prostaglandins in cirrhosis of the liver.Clinical science (London, England : 1979), , Volume: 70, Issue:5, 1986
Selective inhibition of thromboxane synthesis partially protected while inhibition of angiotensin II formation did not protect rats against acute renal failure induced with glycerol.Prostaglandins, leukotrienes, and medicine, , Volume: 21, Issue:1, 1986
Prostacyclin and thromboxane A2 moderate postischemic renal failure.Surgery, , Volume: 98, Issue:2, 1985
Therapeutic trial of thromboxane synthesis inhibition in the hepatorenal syndrome.Gastroenterology, , Volume: 87, Issue:6, 1984
Prostaglandins in vascular tone in experimental obstructive nephropathy.Kidney international, , Volume: 19, Issue:6, 1981
Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day.Alcoholism, clinical and experimental research, , Volume: 32, Issue:11, 2008
Effect of ethanol on the release of prostaglandins from ovine fetal brain stem during gestation.Alcoholism, clinical and experimental research, , Volume: 16, Issue:3, 1992
Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects.Obstetrics and gynecology, , Volume: 71, Issue:1, 1988
Relation between arterial hypoxemia and plasma eicosanoids in neonates with congenital diaphragmatic hernia.The Journal of surgical research, , Volume: 53, Issue:6, 1992
Congenital diaphragmatic hernia: impact of prostanoids in the perioperative period.Archives of disease in childhood, , Volume: 65, Issue:9, 1990
Extracorporeal membrane oxygenation and congenital diaphragmatic hernia: modification of the pulmonary vasoactive profile.Journal of pediatric surgery, , Volume: 20, Issue:6, 1985
Congenital diaphragmatic hernia: association between pulmonary vascular resistance and plasma thromboxane concentrations.Archives of disease in childhood, , Volume: 59, Issue:2, 1984
Immunosuppressive therapy for recurrent aborters with positive antiphospholipid antibodies and alteration of 6ketoPGF1 alpha/TXB2 ratio.Journal of perinatal medicine, , Volume: 25, Issue:6, 1997
Thromboxane dominance and prostacyclin deficiency in habitual abortion.Lancet (London, England), , Apr-13, Volume: 337, Issue:8746, 1991
Lupus anticoagulant, recurrent abortion, and prostacyclin production by cultured smooth muscle cells.Lancet (London, England), , Nov-12, Volume: 2, Issue:8359, 1983
Response of intra-acinar pulmonary microvessels to hypoxia, hypercapnic acidosis, and isocapnic acidosis.Circulation research, , Apr-06, Volume: 82, Issue:6, 1998
Portal infusion of low dosage endotoxin: a model simulating translocation of ruminal endotoxin in cattle.Acta veterinaria Scandinavica, , Volume: 35, Issue:1, 1994
Endotoxin and arachidonic acid metabolites in portal, hepatic and arterial blood of cattle with acute ruminal acidosis.Acta veterinaria Scandinavica, , Volume: 35, Issue:3, 1994
Tumor necrosis factor-induced mortality is reversed with cyclooxygenase inhibition.Annals of surgery, , Volume: 217, Issue:6, 1993
[Plasma renin activity, angiotensin II, angiotensin converting enzyme, thromboxane A2 and prostacyclin I2 levels in pigs with severe hypoxia and hypercapnea and acidosis shock].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 15, Issue:1, 1992
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.International journal of gastrointestinal cancer, , Volume: 32, Issue:1, 2002
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion.Clinical & experimental metastasis, , Volume: 19, Issue:7, 2002
Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells.Laboratory investigation; a journal of technical methods and pathology, , Volume: 81, Issue:3, 2001
Chemoprevention of biliary carcinogenesis in syrian hamsters by the novel carboxamide derivative IS-741 after initiation with N-nitrosobis(2-oxopropyl)amine (BOP).Carcinogenesis, , Volume: 21, Issue:8, 2000
[Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 17, Issue:9, 1997
Urinary excretion of prostacyclin and thromboxane degradation products in patients with ovarian malignancy: effect of cytostatic treatment.British journal of cancer, , Volume: 60, Issue:5, 1989
Altered 1-14C arachidonic acid metabolism in arterial wall from patients with renal cell carcinoma.The Journal of urology, , Volume: 135, Issue:5, 1986
Formation of prostaglandins by ovarian carcinomas.Prostaglandins, , Volume: 29, Issue:5, 1985
[Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation].Kyobu geka. The Japanese journal of thoracic surgery, , Volume: 37, Issue:10, 1984
Prostaglandin concentrations and prostaglandin synthetase activity in N-nitrosomethylurea-induced rat mammary adenocarcinoma.European journal of cancer & clinical oncology, , Volume: 19, Issue:6, 1983
Prevention of postoperative pericardial adhesions by closure of the pericardium with absorbable polymer patches. An experimental study.The Journal of thoracic and cardiovascular surgery, , Volume: 104, Issue:3, 1992
Peritoneal fluid eicosanoids in chronic pelvic pain.Prostaglandins, , Volume: 38, Issue:4, 1989
Release of 6-keto-prostaglandin F1 alpha and thromboxane B2 from mouse peritoneal macrophages during their adhesion and spreading on a glass surface.Prostaglandins, , Volume: 23, Issue:6, 1982
[Prostanoids of the peritoneal fluid and sterility with or without pelvic lesions (endometriosis, postinfectious adhesions)].Pathologie-biologie, , Volume: 34, Issue:2, 1986
Peritoneal fluid prostaglandins and prostanoids in women with endometriosis, chronic pelvic inflammatory disease, and pelvic pain.American journal of obstetrics and gynecology, , Feb-15, Volume: 148, Issue:4, 1984
The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation.Stroke, , Volume: 31, Issue:6, 2000
Platelet function during acetaldehyde intoxication in healthy male volunteers.Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, , Volume: 1, 1987
Exercise, ethanol and arachidonic acid metabolism in healthy men.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
GC/MS assay of prostaglandins in cerebrospinal fluid from humans and monkeys.Advances in alcohol & substance abuse, , Volume: 7, Issue:3-4, 1988
Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects.Obstetrics and gynecology, , Volume: 71, Issue:1, 1988
Decreased systemic formation of prostaglandin E and prostacyclin, and unchanged thromboxane formation, in alcoholics during withdrawal as estimated from metabolites in urine.Clinical science (London, England : 1979), , Volume: 73, Issue:3, 1987
Urinary excretion of 2, 3-dinor-6-keto prostaglandin F1 alpha and platelet thromboxane formation during ethanol withdrawal in alcoholics.Journal of clinical pathology, , Volume: 40, Issue:5, 1987
Relationship between ethanol, HDL, and vascular prostacyclin production.Transactions of the Association of American Physicians, , Volume: 100, 1987
Prostacyclin contributes to inhibition of hypoxic pulmonary vasoconstriction by alkalosis.Prostaglandins, , Volume: 38, Issue:1, 1989
Hyperventilation, alkalosis, prostaglandins, and pulmonary circulation of the newborn.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 61, Issue:6, 1986
[The effect of inhaled nitric oxide on endothelium-derived angiokinetic factors in patients with acute high altitude disease].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 30, Issue:2, 2007
Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 67, Issue:5, 1989
Release of calcitonin gene-related peptide in cardiac anaphylaxis.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 355, Issue:2, 1997
Relevance of mediators to cardiac parameters of isolated anaphylactic guinea-pig heart.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:1, 1995
The effect of three novel thromboxane A2 receptor antagonists (S-1452, AA-2414 and ONO-3708) on the increase in pulmonary pressure caused by Forssman anaphylaxis in guinea-pigs.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:3, 1992
Effect of 3-morpholinosydnonimine (SIN-1) and NG-nitro-L-arginine (NNA) on isolated perfused anaphylactic guinea-pig hearts.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 345, Issue:1, 1992
Leukotrienes, thromboxane A2, and prostaglandins during systemic anaphylaxis in sheep.The American journal of physiology, , Volume: 261, Issue:3 Pt 2, 1991
OKY-046 inhibits anaphylactic bronchoconstriction and reduces histamine level in bronchoalveolar lavage fluid in sensitized guinea pigs.Prostaglandins, , Volume: 39, Issue:6, 1990
Effect of exogenous 5,8,11,14,17-eicosapentaenoic acid on cardiac anaphylaxis.British journal of pharmacology, , Volume: 90, Issue:2, 1987
Inhibition of the release of prostaglandins, thromboxanes, and leukotrienes from anaphylactic lungs by a platelet-activating factor (PAF) antagonist and its stimulation by PAF.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 17B, 1987
Cyclooxygenase blockade elevates leukotriene E4 production during acute anaphylaxis in sheep.The Journal of experimental medicine, , Jun-01, Volume: 163, Issue:6, 1986
Eicosanoids, leukocytes and lung injury.Progress in clinical and biological research, , Volume: 199, 1985
Modulation of eicosanoid release from anaphylactic guinea-pig heart with 5-benzoyl-a-methyl-2-thiophene acetic acid (tiaprofenic acid).Archives internationales de pharmacodynamie et de therapie, , Volume: 278, Issue:2, 1985
Effects of exogenous prostaglandins on the release of leukotriene C4-like immunoreactivity and on coronary flow in indomethacin-treated anaphylactic guinea-pig hearts.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 326, Issue:4, 1984
Effect of inhibition of synthesis and receptor antagonism of SRS-A in cardiac anaphylaxis.British journal of pharmacology, , Volume: 80, Issue:1, 1983
Prostacyclin, thromboxane and glomerular filtration rate are abnormal in sickle cell pregnancy.PloS one, , Volume: 12, Issue:9, 2017
Sickle erythrocytes increase prostacyclin and endothelin-1 production by cultured human endothelial cells under flow conditions.European journal of haematology, , Volume: 68, Issue:3, 2002
Sickle cell vaso-occlusive crisis is associated with abnormalities in the ratio of vasoconstrictor to vasodilator prostanoids.Pediatric research, , Volume: 38, Issue:1, 1995
Elevated urinary levels of thromboxane and prostacyclin metabolities in sickle cell disease reflects activated platelets in the circulation.British journal of haematology, , Volume: 87, Issue:3, 1994
Increased in vivo production of thromboxane in patients with sickle cell disease is accompanied by an impairment of platelet functions to the thromboxane A2 agonist U46619.Arteriosclerosis and thrombosis : a journal of vascular biology, , Volume: 13, Issue:3, 1993
Effects of normal and sickle erythrocytes on prostacyclin release by perfused human umbilical cord veins.American journal of hematology, , Volume: 40, Issue:4, 1992
Decreased prostacyclin levels in sickle-cell disease.Pediatric hematology and oncology, , Volume: 6, Issue:1, 1989
Modification of membrane properties of erythrocytes by PGI2.Thrombosis research, , Jun-15, Volume: 54, Issue:6, 1989
Release of prostacyclin after erythrocyte adhesion to cultured vascular endothelium.The Journal of laboratory and clinical medicine, , Volume: 107, Issue:3, 1986
Decreased prostacyclin levels in sickle cell disease.Pediatrics, , Volume: 71, Issue:5, 1983
Prostacyclin and platelet aggregation in sickle cell disease.Pediatrics, , Volume: 70, Issue:3, 1982
Enhanced external counterpulsation improves peripheral artery flow-mediated dilation in patients with chronic angina: a randomized sham-controlled study.Circulation, , Oct-19, Volume: 122, Issue:16, 2010
Increased serotonin release across the coronary bed during a nonischemic interval in patients with vasospastic angina.Clinical cardiology, , Volume: 19, Issue:6, 1996
Eicosanoid biosynthesis in patients with stable angina: beneficial effects of very low dose aspirin.Journal of the American College of Cardiology, , Volume: 24, Issue:1, 1994
The effects of orally administered atenolol on the coronary hemodynamics and prostaglandin metabolism in angina pectoris patients.Angiology, , Volume: 45, Issue:3, 1994
The effect of caffeine on prostaglandin output from the perfused mesenteric vascular bed of the rat.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:6, 1994
Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction.The American journal of cardiology, , Jun-01, Volume: 73, Issue:15, 1994
Inhibition of platelet aggregation by prostacyclin is attenuated after exercise in patients with angina pectoris.American heart journal, , Volume: 123, Issue:2, 1992
[Clinical study in treating qi-deficiency and blood-stasis syndrome of angina pectoris with qi xue granule].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 12, Issue:11, 1992
Effect of diltiazem on silent ischemic episodes, plasma bradykinin and prostaglandin metabolism.International journal of cardiology, , Volume: 37, Issue:2, 1992
[Relation of coronary heart disease based on traditional Chinese medicine syndrome differentiation and prostaglandin, blood platelet function, and protein C].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:5, 1991
[Anti-angina effect of puerarin and its effect on plasma thromboxane A2 and prostacyclin].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:2, 1990
Prostaglandin I2 half-life regulated by high density lipoprotein is decreased in acute myocardial infarction and unstable angina pectoris.Circulation, , Volume: 81, Issue:6, 1990
[Effects of Codonopsis pilosulae on the synthesis of thromboxane A2 and prostacyclin].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:7, 1990
Hemodynamic, platelet and clinical responses to prostacyclin in unstable angina pectoris.The American journal of cardiology, , May-01, Volume: 65, Issue:16, 1990
[Effect of a single episode of exertion on serum 6-keto-PGF1 alpha concentration in healthy individuals and patients with exercise-induced stable angina pectoris].Polski tygodnik lekarski (Warsaw, Poland : 1960), , Jun-05, Volume: 44, Issue:23, 1989
Plasma bradykinin and prostaglandin metabolism and exercise testing in patients with silent myocardial ischemia compared with patients with painful myocardial ischemia.Japanese circulation journal, , Volume: 53, Issue:11, 1989
[Platelet functions in patients with acute myocardial infarction].Zhonghua xin xue guan bing za zhi, , Volume: 17, Issue:5, 1989
Radioimmunoassay of thromboxane B2 and its preliminary applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:1, 1988
[Newly developed stenocardia: functional activity of thrombocytes].Kardiologiia, , Volume: 28, Issue:7, 1988
Effects of iloprost (ZK 36374), a prostacyclin derivative, on platelet function after ischaemic exercise in patients with stable angina pectoris.Thrombosis research, , Oct-15, Volume: 48, Issue:2, 1987
[A clinical trial of sheng-mai liquor in the treatment of ischemic heart disease].Zhonghua xin xue guan bing za zhi, , Volume: 15, Issue:3, 1987
Biochemical evidence of platelet activation in patients with persistent unstable angina.Journal of the American College of Cardiology, , Volume: 10, Issue:5, 1987
[Clinical and experimental study on the treatment of angina pectoris with kuo guan granules].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 7, Issue:6, 1987
[Unstable stenocardia: functional activity and free cytoplasmic calcium of thrombocytes and vaso- and thrombocytoactive prostanoids].Kardiologiia, , Volume: 27, Issue:10, 1987
Effects of a selective thromboxane synthetase inhibitor (OKY-046) in patients with coronary artery disease during exercise.Japanese heart journal, , Volume: 28, Issue:5, 1987
Fibrinopeptide A and platelet factor levels in unstable angina pectoris.Circulation, , Volume: 75, Issue:1, 1987
Myocardial ischaemia triggers formation of thromboxane.Lancet (London, England), , Sep-05, Volume: 2, Issue:8558, 1987
Impaired cardiac PGI2 and PGE2 biosynthesis in patients with angina pectoris.American heart journal, , Volume: 112, Issue:3, 1986
Platelet activation in unstable coronary disease.The New England journal of medicine, , Oct-16, Volume: 315, Issue:16, 1986
[Thromboxane and prostacyclin in patients with stenocardia in induced and spontaneous ischemia of the myocardium].Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, , Volume: 9, Issue:1, 1986
[Hemodynamic effects of nitroglycerin following acute inhibition of prostaglandin synthesis].Zeitschrift fur Kardiologie, , Volume: 75, Issue:11, 1986
Development of quantitative analysis of plasma thromboxane B2 by gas chromatography-mass spectrometry.Japanese circulation journal, , Volume: 49, Issue:3, 1985
Effects of selective thromboxane synthetase inhibitor OKY-046 on plasma prostaglandins in patients with coronary artery disease during exercise.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Cardiac prostaglandin synthesis in spontaneous and in effort angina.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Coronary spasm, prostaglandin and HLA factors.Japanese circulation journal, , Volume: 49, Issue:1, 1985
The effects of organic nitrates on prostacyclin biosynthesis and platelet function in humans.Circulation, , Volume: 70, Issue:2, 1984
Hemodynamic effects of intravenous prostacyclin in stable angina pectoris.The American journal of cardiology, , Sep-01, Volume: 52, Issue:5, 1983
[Biochemistry of coronary artery disease--prostaglandins].Rinsho byori. The Japanese journal of clinical pathology, , Volume: 31, Issue:8, 1983
Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease.The New England journal of medicine, , Mar-19, Volume: 304, Issue:12, 1981
Prostacyclin and variant angina.Annals of the New York Academy of Sciences, , Volume: 454, 1985
[Plasma levels of thromboxane B2 and 6-keto PGF1 alpha in patients with variant angina].Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, , Volume: 74, Issue:6, 1985
Coronary spasm, prostaglandin and HLA factors.Japanese circulation journal, , Volume: 49, Issue:1, 1985
Treatment of unstable angina pectoris with modified nuan gan jian--a report of 33 cases.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 24, Issue:4, 2004
Transcardiac 5-hydroxytryptamine release and impaired coronary endothelial function in patients with vasospastic angina.Clinical and experimental pharmacology & physiology, , Volume: 25, Issue:12, 1998
Hemodynamic, platelet and clinical responses to prostacyclin in unstable angina pectoris.The American journal of cardiology, , May-01, Volume: 65, Issue:16, 1990
Prostaglandin I2 half-life regulated by high density lipoprotein is decreased in acute myocardial infarction and unstable angina pectoris.Circulation, , Volume: 81, Issue:6, 1990
[Platelet functions in patients with acute myocardial infarction].Zhonghua xin xue guan bing za zhi, , Volume: 17, Issue:5, 1989
[Newly developed stenocardia: functional activity of thrombocytes].Kardiologiia, , Volume: 28, Issue:7, 1988
Biochemical evidence of platelet activation in patients with persistent unstable angina.Journal of the American College of Cardiology, , Volume: 10, Issue:5, 1987
[Unstable stenocardia: functional activity and free cytoplasmic calcium of thrombocytes and vaso- and thrombocytoactive prostanoids].Kardiologiia, , Volume: 27, Issue:10, 1987
Fibrinopeptide A and platelet factor levels in unstable angina pectoris.Circulation, , Volume: 75, Issue:1, 1987
Impaired cardiac PGI2 and PGE2 biosynthesis in patients with angina pectoris.American heart journal, , Volume: 112, Issue:3, 1986
Platelet activation in unstable coronary disease.The New England journal of medicine, , Oct-16, Volume: 315, Issue:16, 1986
[Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 25, Issue:1, 2009
AAV-PGIS gene transfer improves hypoxia-induced pulmonary hypertension in mice.Biochemical and biophysical research communications, , Nov-23, Volume: 363, Issue:3, 2007
[Effect of aspirin on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 19, Issue:4, 2003
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs.American journal of physiology. Lung cellular and molecular physiology, , Volume: 284, Issue:2, 2003
Effect of Ibuprofen on interleukin-1beta-induced abnormalities in hemodynamics and oxygen metabolism in rabbits.Shock (Augusta, Ga.), , Volume: 20, Issue:6, 2003
Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension.Cardiovascular research, , Volume: 55, Issue:1, 2002
Integration of hypoxic dilation signaling pathways for skeletal muscle resistance arteries.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 283, Issue:2, 2002
Hypoxic induction of cox-2 regulates proliferation of human pulmonary artery smooth muscle cells.American journal of respiratory cell and molecular biology, , Volume: 27, Issue:6, 2002
Exaggerated hypoxic pulmonary hypertension in endothelin B receptor-deficient rats.American journal of physiology. Lung cellular and molecular physiology, , Volume: 282, Issue:4, 2002
Factors that increase the contractile tone of the ductus arteriosus also regulate its anatomic remodeling.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 281, Issue:1, 2001
Dose-response to inhaled aerosolized prostacyclin for hypoxemia due to ARDS.Chest, , Volume: 117, Issue:3, 2000
Effects of prostaglandins and leukotrienes on hypoxic pulmonary vasoconstriction in rats.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 20, Issue:3, 2000
Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats.Anesthesia and analgesia, , Volume: 89, Issue:4, 1999
Prostanoids: early mediators in the secondary injury that develops after unilateral pulmonary contusion.The Journal of trauma, , Volume: 46, Issue:5, 1999
Response of intra-acinar pulmonary microvessels to hypoxia, hypercapnic acidosis, and isocapnic acidosis.Circulation research, , Apr-06, Volume: 82, Issue:6, 1998
Activated endothelial cells elicit paracrine induction of epithelial chloride secretion. 6-Keto-PGF1alpha is an epithelial secretagogue.The Journal of clinical investigation, , Sep-15, Volume: 102, Issue:6, 1998
Cerebral arteriolar dilation to hypoxia: role of prostanoids.The American journal of physiology, , Volume: 272, Issue:1 Pt 2, 1997
Systemic levels of 6-keto-prostaglandin F1 alpha following administration of inhaled aerosolized prostacyclin.Anaesthesia and intensive care, , Volume: 25, Issue:6, 1997
Effects of tetramethylpyrazine on the release of PGI2 and TXA2 in the hypoxic isolated rat heart.Molecular and cellular biochemistry, , Volume: 167, Issue:1-2, 1997
Oxygen deprivation and reoxygenation augment prostacyclin synthesis in cultured ventricular myocytes.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 54, Issue:3, 1996
Some humoral factors and their interaction on acute hypoxic pulmonary pressor response.Chinese medical journal, , Volume: 107, Issue:2, 1994
NMDA receptors mediate anoxia/aglycemia-induced release of eicosanoids in immature rat hippocampal slices: utility of an in vitro "ischemic" superfusion model with temporary arrest of medium flow.Folia neuropathologica, , Volume: 32, Issue:3, 1994
Effects of hypoxia on platelet activation in pilots.Aviation, space, and environmental medicine, , Volume: 65, Issue:7, 1994
Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine.Shock (Augusta, Ga.), , Volume: 2, Issue:5, 1994
Prostanoid production in hypoxic rat isolated atria: influence of acute diabetes.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:4, 1994
Endothelium-dependent response of human internal mammary artery to hypoxia.The American journal of physiology, , Volume: 264, Issue:2 Pt 2, 1993
Relation between arterial hypoxemia and plasma eicosanoids in neonates with congenital diaphragmatic hernia.The Journal of surgical research, , Volume: 53, Issue:6, 1992
Cellular mechanisms that control pulmonary vascular tone during hypoxia and normoxia. Possible role of Ca2+ATPases.The American review of respiratory disease, , Volume: 145, Issue:6, 1992
Effect of endotoxin on hypoxic pulmonary vasoconstriction--the role of prostaglandins and leukotrienes.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:1, 1992
[Plasma renin activity, angiotensin II, angiotensin converting enzyme, thromboxane A2 and prostacyclin I2 levels in pigs with severe hypoxia and hypercapnea and acidosis shock].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 15, Issue:1, 1992
Alteration in hypoxic pulmonary vasoconstriction during hypothermia in dogs.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:3, 1992
Hypoxia inhibits renal thromboxane and not prostacyclin release.Circulatory shock, , Volume: 33, Issue:4, 1991
Leukotrienes and prostaglandins in fetal lung liquid.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 68, Issue:5, 1990
The effect of hypoxia on angiotensin-stimulated release of PGI2 from the splanchnic bed.The Journal of trauma, , Volume: 30, Issue:8, 1990
Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 67, Issue:5, 1989
Prostacyclin contributes to inhibition of hypoxic pulmonary vasoconstriction by alkalosis.Prostaglandins, , Volume: 38, Issue:1, 1989
The effect of hypoxia on rat splanchnic prostanoid output.Prostaglandins, , Volume: 38, Issue:5, 1989
Effects of cigarette smoking on hemodynamics and hypoxic pulmonary vasoconstriction: role of prostaglandins and leukotrienes.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 9, Issue:4, 1989
Relation of TXA2 and PGI2 to the difference in hypoxic pulmonary vasoconstriction between different strains of rats.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 9, Issue:3, 1989
Release of thromboxane A2 by low-dose almitrine in the hypoxic dog.The European respiratory journal, , Volume: 1, Issue:8, 1988
Age-dependent effects of indomethacin on hypoxic vasoconstriction in neonatal lamb lungs.Pediatric research, , Volume: 23, Issue:6, 1988
The carbochromene derivative AD6 reduces the TxB2/6-keto-PGF1 alpha ratio in cerebral cortex during hypoxia and recovery and leukotriene synthesis in brain tissue, in the rat.Prostaglandins, , Volume: 35, Issue:1, 1988
Role of eicosanoids in hypoxic vasoconstriction in isolated lamb lungs.The American journal of physiology, , Volume: 253, Issue:3 Pt 2, 1987
Synthesis of prostaglandins, TXA2 and PGI2, during one lung anesthesia.Prostaglandins, , Volume: 34, Issue:5, 1987
Experimental studies on pulmonary vascular response to alveolar hypoxia during almitrine infusion in anesthetized dogs.Hiroshima journal of medical sciences, , Volume: 36, Issue:4, 1987
Effect of hypoxia on prostacyclin production in cultured pulmonary artery endothelium.Prostaglandins, , Volume: 31, Issue:6, 1986
Effects of verapamil on thromboxane synthesis and pulmonary hypertension in sheep.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 9, Issue:3, 1986
Mediator release from human lung under conditions of reduced oxygen tension.The Journal of pharmacology and experimental therapeutics, , Volume: 238, Issue:1, 1986
Effects of hypoxia and anoxia on the ex vivo release of prostaglandins from mouse cortical slices.Journal of neurochemistry, , Volume: 47, Issue:6, 1986
Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:4, 1986
Thromboxane A2 and prostacyclin do not modulate pulmonary hemodynamics during exercise in sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 61, Issue:5, 1986
Effects of indomethacin on estradiol-induced attenuation of hypoxic vasoconstriction in lamb lungs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 61, Issue:6, 1986
Thromboxane as a mediator of pulmonary dysfunction during intravascular complement activation in sheep.The American review of respiratory disease, , Volume: 133, Issue:2, 1986
Effects of high frequency oscillatory ventilation compared to conventional ventilation upon pulmonary vascular prostanoid production in neonatal piglets.Prostaglandins, leukotrienes, and medicine, , Volume: 17, Issue:1, 1985
Pulmonary dysfunction secondary to soft-tissue endotoxin.Archives of surgery (Chicago, Ill. : 1960), , Volume: 120, Issue:2, 1985
Relation of prostanoids to strength of hypoxic vasoconstriction in dogs with lobar atelectasis.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 59, Issue:1, 1985
Prostaglandins and estradiol-induced attenuation of hypoxic pulmonary vasoconstriction.Chest, , Volume: 88, Issue:4 Suppl, 1985
Hypoxia enhances prostaglandin synthesis in renal mesangial cell cultures.Prostaglandins, , Volume: 30, Issue:1, 1985
The role of prostacyclin in the hypercapnic and hypoxic cerebrovascular dilations.Life sciences, , May-07, Volume: 34, Issue:19, 1984
Failure of acute hypoxia to alter pulmonary prostaglandin metabolism in dogs.Prostaglandins, , Volume: 25, Issue:5, 1983
Effect of cholesterol feeding and gender on the response of the isolated rat heart to hypoxia.Canadian journal of physiology and pharmacology, , Volume: 60, Issue:12, 1982
Hypoxia stimulates prostacyclin generation by dog lung in vitro.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:4, 1982
Thromboxane and prostacyclin (epoprostenol) during exercise in diffuse pulmonary fibrosis.Lancet (London, England), , Nov-27, Volume: 2, Issue:8309, 1982
[Effect of hypoxemia and pulmonary thromboembolism on plasma levels of 6-keto PGF 1 alpha, TxB, histamine and serotonin in anesthetized dogs (author's transl)].Nihon Kyobu Shikkan Gakkai zasshi, , Volume: 19, Issue:8, 1981
Developmental changes in synthesis of and responsiveness to prostaglandins I2 and E2 in hypoxic lamb lungs.Canadian journal of physiology and pharmacology, , Volume: 76, Issue:7-8
Estrogen modulates permeability and prostaglandin levels in the rabbit urinary bladder.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 80, Issue:2-3
[Prostaglandins content in the blood of newborns with various types of hypoxia].Fiziologicheskii zhurnal, , Volume: 39, Issue:2-3
The role of prostacyclin in the mesenteric traction syndrome during anesthesia for abdominal aortic reconstructive surgery.Annals of surgery, , Volume: 209, Issue:3, 1989
Synthetic arterial grafts cause prolonged increase in the in vivo formation of thromboxane and prostacyclin in humans.Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, , Volume: 187, Issue:3, 1987
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Dietary fish protein lowers blood pressure and alters tissue polyunsaturated fatty acid composition in spontaneously hypertensive rats.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 19, Issue:4, 2003
Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit.Prostaglandins & other lipid mediators, , Volume: 70, Issue:3-4, 2003
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The pharmacokinetics of flurbiprofen in younger and elderly patients with rheumatoid arthritis.Journal of clinical pharmacology, , Volume: 32, Issue:1, 1992
Study of mechanisms of glucocorticoid hypertension in rats: endothelial related changes and their amelioration by dietary fish oils.British journal of pharmacology, , Volume: 106, Issue:2, 1992
The functional and structural changes of the glomerulus throughout the course of murine lupus nephritis.Journal of the American Society of Nephrology : JASN, , Volume: 3, Issue:4, 1992
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The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus.Diabetologia, , Volume: 34, Issue:4, 1991
Maternal and fetal atrial natriuretic peptide levels, maternal plasma renin activity, angiotensin II, prostacyclin and thromboxane A2 levels in normal and preeclamptic pregnancies.The Tohoku journal of experimental medicine, , Volume: 165, Issue:2, 1991
Endotoxin-induced myocardial depression in rats: effect of ibuprofen and SDZ 64-688, a platelet activating factor receptor antagonist.The Journal of surgical research, , Volume: 48, Issue:6, 1990
Short-term therapy of atherosclerosis with low dose indomethacin: an experimental study.Journal of medical primatology, , Volume: 19, Issue:7, 1990
Effects of a selective thromboxane synthetase inhibitor OKY-046 on experimental diabetic nephropathy.Nephron, , Volume: 56, Issue:3, 1990
Hypertension in bone marrow transplanted patients.Acta clinica Belgica, , Volume: 44, Issue:5, 1989
Sorbinil suppresses glomerular prostaglandin production in the streptozotocin diabetic rat.Metabolism: clinical and experimental, , Volume: 38, Issue:7, 1989
Role for local prostaglandin and thromboxane production in the regulation of glomerular filtration rate in the rat with streptozocin-induced diabetes.The Journal of laboratory and clinical medicine, , Volume: 113, Issue:6, 1989
Changes in arachidonic acid metabolite patterns in alloxan-induced diabetic rats.Pharmacology, , Volume: 39, Issue:5, 1989
Prevention of acute cyclosporine A nephrotoxicity by a thromboxane synthetase inhibitor.Transplantation proceedings, , Volume: 20, Issue:3 Suppl 3, 1988
The effect of dietary fish oil and long-term salt loading on blood pressure and eicosanoid metabolism in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 15, Issue:4, 1988
Effect of high-dose etodolac on renal function.Clinical pharmacology and therapeutics, , Volume: 42, Issue:3, 1987
Dietary suppression of prostaglandin synthesis does not accelerate DOCA/salt hypertension in rats.Clinical and experimental pharmacology & physiology, , Volume: 14, Issue:6, 1987
Effects of selenium-deficient diets on the production of prostaglandins and other oxygenated metabolites of arachidonic acid and linoleic acid by rat and rabbit aortae.Biochimica et biophysica acta, , Sep-25, Volume: 921, Issue:2, 1987
6-keto prostaglandin F1 alpha and thromboxane B2 in isolated, buffer-perfused lungs from monocrotaline pyrrole-treated rats.Experimental lung research, , Volume: 12, Issue:3, 1987
High protein intake stimulates glomerular prostaglandin formation in remnant kidneys.The American journal of physiology, , Volume: 252, Issue:6 Pt 2, 1987
Effect of spironolactone on renal prostaglandin excretion in patients with liver cirrhosis and ascites.Journal of hepatology, , Volume: 3, Issue:2, 1986
Inhibition of compensatory renal growth by indomethacin.Prostaglandins, , Volume: 31, Issue:2, 1986
Dietary fat and selenium effects on ex vivo prostaglandin production in rat colon, kidney, and blood.Nutrition and cancer, , Volume: 8, Issue:2, 1986
Effects of low-dose aspirin on responses to furosemide.Journal of clinical pharmacology, , Volume: 26, Issue:2, 1986
Heated fat, vitamin E and vascular eicosanoids.Lipids, , Volume: 20, Issue:7, 1985
Delayed effects of experimental maternal diabetes on plasma cholesterol level and vascular prostacyclin synthesis in the offspring.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 179, Issue:4, 1985
Estradiol is responsible for reduced renal prostaglandin dehydrogenase activity in female rats.Biochimica et biophysica acta, , Mar-06, Volume: 833, Issue:3, 1985
High potassium intake selectively increases urinary PGF2 alpha excretion in the rat.The American journal of physiology, , Volume: 248, Issue:3 Pt 2, 1985
Dietary fish oil prevents dexamethasone induced hypertension in the rat.Clinical science (London, England : 1979), , Volume: 69, Issue:6, 1985
Continuous monitoring of prostacyclin production by the isolated, intact, rat aorta using a bioassay technique.Journal of pharmacological methods, , Volume: 11, Issue:4, 1984
The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients.British journal of clinical pharmacology, , Volume: 17 Suppl 1, 1984
Dissociation of effects of dietary fatty acids on blood pressure and prostanoid metabolism in Goldblatt hypertensive rats.Journal of hypertension, , Volume: 2, Issue:1, 1984
Altered aortic prostaglandin synthesis in a mild form of diabetes and the influence of dietary cholesterol.The Journal of laboratory and clinical medicine, , Volume: 104, Issue:3, 1984
Effects of mild physical exercise on serum lipoproteins and metabolites of arachidonic acid: a controlled randomised trial in middle aged men.British medical journal (Clinical research ed.), , Feb-25, Volume: 288, Issue:6417, 1984
The effect of zinc deficiency on prostaglandin synthesis in rat testes.The Journal of nutrition, , Volume: 114, Issue:11, 1984
Renin-angiotensin system and prostacyclin biosynthesis in streptozotocin diabetic rats.European journal of pharmacology, , Oct-14, Volume: 94, Issue:1-2, 1983
6-Keto-PGF1 alpha synthesis in diabetic rat aorta: effect of substrate concentration and cholesterol feeding.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 171, Issue:3, 1982
Production of 6-oxo-prostaglandin F1alpha by rat aorta: influence of diabetes, insulin treatment, and caloric deprivation.Diabetes, , Volume: 30, Issue:11, 1981
Inhalation exposure to JP-8 jet fuel alters pulmonary function and substance P levels in Fischer 344 rats.Journal of applied toxicology : JAT, , Volume: 15, Issue:4
Effect of arachidonic acid-rich oil on lipids and arachidonate metabolites in ethanol- treated rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 64, Issue:4-5
Exercise training, indomethacin, and isoproterenol-induced myocardial necrosis in the rat.Basic research in cardiology, , Volume: 86, Issue:1
Prostaglandin levels of primary bone tumor tissues correlate with peritumoral edema demonstrated by magnetic resonance imaging.Cancer, , Jan-15, Volume: 79, Issue:2, 1997
Increased prostacyclin biosynthesis in patients with osteoid osteoma.Eicosanoids, , Volume: 4, Issue:3, 1991
Prostaglandins in osteoid osteoma.International orthopaedics, , Volume: 15, Issue:1, 1991
Biochemical markers and skeletal metabolism in carcinoma of the prostate. Use of decision matrix theory and ROC analysis.British journal of urology, , Volume: 57, Issue:6, 1985
Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors.The American journal of pediatric hematology/oncology, ,Spring, Volume: 7, Issue:1, 1985
Prostaglandin-independent stimulation of bone resorption in mouse calvariae and in isolated rat osteoclasts by thyroid hormones (T4, and T3).Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 217, Issue:2, 1998
Tumor necrosis factors alpha and beta can stimulate bone resorption in cultured mouse calvariae by a prostaglandin-independent mechanism.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, , Volume: 8, Issue:2, 1993
Prostaglandin release by normal and osteomyelitic human bones.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 43, Issue:1, 1991
Parathyroid hormone stimulates prostanoid formation in mouse calvarial bones.Acta endocrinologica, , Volume: 120, Issue:3, 1989
Enhancement of human dental cyst PGI2 formation by platelet derived growth factor and its role in cyst growth and bone resorption.Archives of oral biology, , Volume: 34, Issue:3, 1989
Inhibition by 17 beta-estradiol of PTH stimulated resorption and prostaglandin production in cultured neonatal mouse calvariae.Biochemical and biophysical research communications, , Sep-29, Volume: 163, Issue:3, 1989
Bone-resorbing activity of thyroid hormones is related to prostaglandin production in cultured neonatal mouse calvaria.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, , Volume: 4, Issue:3, 1989
Prostaglandins in human cholesteatoma and granulation tissue.The American journal of otology, , Volume: 9, Issue:3, 1988
Use of minoxidil to demonstrate that prostacyclin is not the mediator of bone resorption stimulated by growth factors in mouse calvariae.Endocrinology, , Volume: 123, Issue:2, 1988
Synthetic human parathyroid hormone fragment stimulates prostaglandin E2 synthesis by chick calvariae.Endocrinology, , Volume: 120, Issue:1, 1987
Prostaglandins in pathological bone resorption.Agents and actions, , Volume: 19, Issue:1-2, 1986
Alpha and beta human transforming growth factors stimulate prostaglandin production and bone resorption in cultured mouse calvaria.Proceedings of the National Academy of Sciences of the United States of America, , Volume: 82, Issue:13, 1985
6-Keto-prostaglandin E1-stimulated bone resorption in organ culture.Calcified tissue international, , Volume: 36, Issue:4, 1984
Effects of the prostacyclin products, 6-keto prostaglandin E1 and 6-keto prostaglandin F1 alpha, on bone resorption in vitro.Prostaglandins, leukotrienes, and medicine, , Volume: 15, Issue:1, 1984
Prostacyclin potently resorbs bone in vitro.Advances in prostaglandin and thromboxane research, , Volume: 6, 1980
Rosuvastatin in experimental brain trauma: improved capillary patency but no effect on edema or cerebral blood flow.Microvascular research, , Volume: 88, 2013
Effects of selective and non-selective cyclooxygenase inhibition against neurological deficit and brain oedema following closed head injury in mice.Brain research, , Jan-23, Volume: 1491, 2013
Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up.Journal of the neurological sciences, , Dec-15, Volume: 287, Issue:1-2, 2009
Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion.The Journal of nutritional biochemistry, , Volume: 17, Issue:4, 2006
Indomethacin prevents the development of experimental ammonia-induced brain edema in rats after portacaval anastomosis.Hepatology (Baltimore, Md.), , Volume: 34, Issue:2, 2001
Glioma prostaglandin levels correlate with brain edema.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 18, Issue:2, 1998
[Role of arachidonic acid metabolites on development of ischemic cerebral edema in rat middle cerebral artery occlusion].No to shinkei = Brain and nerve, , Volume: 46, Issue:1, 1994
Tumor prostaglandin levels correlate with edema around supratentorial meningiomas.Neurosurgery, , Volume: 33, Issue:2, 1993
"Ex vivo" release of eicosanoid from human brain tissue: its relevance in the development of brain edema.Neurosurgery, , Volume: 28, Issue:6, 1991
Eicosanoid production by brain tumours in vivo--evidence for intracranial compartmentation.Journal of neuro-oncology, , Volume: 11, Issue:3, 1991
OKY-046 inhibits thromboxane synthesis with no effect on brain edema and neurological status in head traumatized rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 36, Issue:1, 1989
Thromboxane synthetase inhibition with imidazole increases blood flow in ischemic penumbra.Neurosurgery, , Volume: 22, Issue:2, 1988
Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema.Stroke, , Volume: 19, Issue:3, 1988
Head injury induces increased prostaglandin synthesis in rat brain.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 7, Issue:1, 1987
Lipoxygenase metabolites of arachidonic acid and the development of ischaemic cerebral oedema.Neurological research, , Volume: 8, Issue:1, 1986
Polyamine and prostaglandin markers in focal cerebral ischemia.Neurosurgery, , Volume: 17, Issue:4, 1985
[Prostaglandin metabolism in ischemic brain edema].Nihon geka hokan. Archiv fur japanische Chirurgie, , Sep-01, Volume: 54, Issue:5, 1985
Rosuvastatin in experimental brain trauma: improved capillary patency but no effect on edema or cerebral blood flow.Microvascular research, , Volume: 88, 2013
Effects of selective and non-selective cyclooxygenase inhibition against neurological deficit and brain oedema following closed head injury in mice.Brain research, , Jan-23, Volume: 1491, 2013
Moderate hypothermia improves imbalances of thromboxane A2 and prostaglandin I2 production after traumatic brain injury in humans.Critical care medicine, , Volume: 28, Issue:12, 2000
OKY-046 inhibits thromboxane synthesis with no effect on brain edema and neurological status in head traumatized rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 36, Issue:1, 1989
Experimental closed head injury in rats: prostaglandin production in a noninjured zone.Neurosurgery, , Volume: 22, Issue:5, 1988
Eicosanoids in human ventricular cerebrospinal fluid following severe brain injury.Prostaglandins, , Volume: 34, Issue:6, 1987
Glioma prostaglandin levels correlate with brain edema.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 18, Issue:2, 1998
Tumor prostaglandin levels correlate with edema around supratentorial meningiomas.Neurosurgery, , Volume: 33, Issue:2, 1993
"Ex vivo" release of eicosanoid from human brain tissue: its relevance in the development of brain edema.Neurosurgery, , Volume: 28, Issue:6, 1991
Eicosanoid production by brain tumours in vivo--evidence for intracranial compartmentation.Journal of neuro-oncology, , Volume: 11, Issue:3, 1991
Production of prostaglandins and thromboxane by isolated cells from intracranial tumours.Journal of neurology, neurosurgery, and psychiatry, , Volume: 47, Issue:6, 1984
Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer.Clinical cancer research : an official journal of the American Association for Cancer Research, , Volume: 7, Issue:11, 2001
Prostacyclin/thromboxane ratio in human breast cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, , Volume: 12, Issue:5, 1991
Human platelet-tumor cell interactions vary with the tumor cell lines.Invasion & metastasis, , Volume: 6, Issue:6, 1986
The concentrations of 6-keto-PGF1 alpha and TXB2 in plasma samples from patients with benign and malignant tumours of the breast.Prostaglandins, , Volume: 29, Issue:4, 1985
Prostacyclin and thromboxane in breast cancer: relationship between steroid receptor status and medroxyprogesterone acetate.British journal of cancer, , Volume: 51, Issue:5, 1985
Suppression of plasma 6-keto-prostaglandin F1 alpha and 13,14-dihydro-15-keto-prostaglandin F2 alpha by aminoglutethimide in advanced breast cancer.British journal of cancer, , Volume: 48, Issue:4, 1983
Breast cancer, its recurrence, and patient survival in relation to tumor prostaglandins.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 12, 1983
Prostaglandins in breast cancer: relationship to disease stage and hormone status.British journal of cancer, , Volume: 48, Issue:5, 1983
[Clinical study on main visceral damage and multiple organ failure (MOF) following severe burns].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 9, Issue:3, 1993
Airway acid injury following smoke inhalation.Progress in clinical and biological research, , Volume: 264, 1988
Cardiopulmonary responses after spontaneous inhalation of Douglas fir smoke in goats.The Journal of trauma, , Volume: 28, Issue:2, 1988
The pulmonary lesion of smoke inhalation in an ovine model.Circulatory shock, , Volume: 18, Issue:4, 1986
Prostacyclin in human non-small cell lung cancers.Chest, , Volume: 125, Issue:5 Suppl, 2004
[Study on advanced non-small cell lung cancer patients with Qi deficiency and blood stasis syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 14, Issue:12, 1994
Sensitivity of tumoricidal function in macrophages from different anatomical sites of cancer patients to modulation of arachidonic acid metabolism.Cancer research, , Jul-15, Volume: 53, Issue:14, 1993
Suppression of the nitric oxide pathway in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-signaling inhibitors.Hypertension (Dallas, Tex. : 1979), , Volume: 56, Issue:6, 2010
Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2.Clinical science (London, England : 1979), , Volume: 95, Issue:1, 1998
The effects of a COX-2 inhibitor meloxicam on squamous cell carcinoma of the esophagus in vivo.International journal of cancer, , Apr-01, Volume: 122, Issue:7, 2008
[Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 17, Issue:9, 1997
Increased thromboxane A2 production at primary tumor site in metastasizing squamous cell carcinoma of the larynx.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:1, 1993
Prostaglandins in squamous cell carcinoma of the larynx: tumor and peritumor synthesis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Plasma thromboxane A2 and prostacyclin concentrations in squamous cell carcinoma of the head and neck.Journal of surgical oncology, , Volume: 38, Issue:1, 1988
Increased plasma-6-oxo-PGF1-alpha but normal PGI2 half-life in patients with maxillo-facial tumors.Progress in clinical and biological research, , Volume: 242, 1987
Prostaglandins in pathological bone resorption.Agents and actions, , Volume: 19, Issue:1-2, 1986
[Changes of platelet aggregation, serum thromboxane and prostacyclin in lung cancer and pulmonary metastatic patients following operation].Kyobu geka. The Japanese journal of thoracic surgery, , Volume: 37, Issue:10, 1984
NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.Basic research in cardiology, , Volume: 103, Issue:5, 2008
[Changes in parameters of hemorheology and circulation 6-keto-PGF1 alpha and TXB2 in dilated cardiomyopathy].Zhonghua nei ke za zhi, , Volume: 30, Issue:4, 1991
Phospholipid metabolism in cardiomyopathic hamster heart cells.Circulation research, , Volume: 69, Issue:4, 1991
Cyclo-oxygenase-2 -765G > C promoter variants are associated with lower carotid plaque echogenicity in Japanese.Cerebrovascular diseases (Basel, Switzerland), , Volume: 27, Issue:1, 2009
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins.Circulation research, , Mar-19, Volume: 94, Issue:5, 2004
Vasoactive and atherogenic effects of cigarette smoking: a study of monozygotic twins discordant for smoking.BMJ (Clinical research ed.), , Oct-15, Volume: 297, Issue:6654, 1988
[Arachidonic acid metabolism following aneurysm rupture].European archives of psychiatry and neurological sciences, , Volume: 236, Issue:2, 1986
Arterial eicosanoid production following chronic exposure to a periarterial haematoma.Journal of neurology, neurosurgery, and psychiatry, , Volume: 47, Issue:7, 1984
Progression of carotid atherosclerosis and the role of endothelin in diabetic patients.Research communications in molecular pathology and pharmacology, , Volume: 108, Issue:1-2
Panax Notoginseng Saponins Combined with Dual Antiplatelet Drugs Potentiates Anti-Thrombotic Effect with Alleviated Gastric Injury in A Carotid Artery Thrombosis Rat Model.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, , Volume: 31, Issue:8, 2022
Effects of Cydonia oblonga Miller extracts on blood hemostasis, coagulation and fibrinolysis in mice, and experimental thrombosis in rats.Journal of ethnopharmacology, , May-28, Volume: 154, Issue:1, 2014
Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.The Journal of clinical investigation, , Volume: 122, Issue:4, 2012
Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury.Arzneimittel-Forschung, , Volume: 62, Issue:12, 2012
[Study of dahuangzhechong pills on anti-arterial thrombosis with the orthogonal design].Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, , Volume: 35, Issue:1, 2012
Effects of scorpion venom bioactive polypolypeptides on platelet aggregation and thrombosis and plasma 6-keto-PG F1alpha and TXB2 in rabbits and rats.Toxicon : official journal of the International Society on Toxinology, , Volume: 46, Issue:2, 2005
Honokiol inhibits arterial thrombosis through endothelial cell protection and stimulation of prostacyclin.Acta pharmacologica Sinica, , Volume: 26, Issue:9, 2005
Inhibitory effects of nimodipine on platelet aggregation and thrombosis.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 19, Issue:2, 1998
The role of thromboxane (TX) A2 in rabbit arterial thrombosis induced by endothelial damage.Thrombosis research, , Jul-01, Volume: 59, Issue:1, 1990
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with thromboxane synthetase inhibitor dazoxiben hydrochloride, (UK-37, 248-01).Thrombosis research, , Dec-01, Volume: 28, Issue:5, 1982
Endotoxin and arachidonic acid metabolites in portal, hepatic and arterial blood of cattle with acute ruminal acidosis.Acta veterinaria Scandinavica, , Volume: 35, Issue:3, 1994
Portal infusion of low dosage endotoxin: a model simulating translocation of ruminal endotoxin in cattle.Acta veterinaria Scandinavica, , Volume: 35, Issue:1, 1994
Prostaglandin and thromboxane concentrations in plasma and lung lavage fluids during sequential infection of vaccinated and nonvaccinated calves with bovine respiratory syncytial virus.American journal of veterinary research, , Volume: 50, Issue:8, 1989
Hemodynamics, plasma eicosanoid concentrations, and plasma biochemical changes in calves given multiple injections of Escherichia coli endotoxin.American journal of veterinary research, , Volume: 49, Issue:1, 1988
The efficacy of dexamethasone and flunixin meglumine in treating endotoxin-induced changes in calves.Veterinary research communications, , Volume: 11, Issue:5, 1987
Prostaglandin F2 alpha and prostacyclin imbalance in cows with placental retention: new findings.Annales de recherches veterinaires. Annals of veterinary research, , Volume: 17, Issue:4, 1986
Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice.Biochemical and biophysical research communications, , Jul-18, Volume: 372, Issue:1, 2008
Effect of modifiers of arachidonic acid metabolism on radiation transformation and eicosanoid formation in C3H/10T1/2 cells.Cancer biochemistry biophysics, , Volume: 14, Issue:3, 1994
[Value of calcitonin and 6-oxo-prostaglandin Fl alpha in the differentiation of lung cancers].Acta medica Austriaca, , Volume: 14, Issue:2, 1987
Effect of intraventricular haemorrhage and rebleeding following subarachnoid haemorrhage on CSF eicosanoids.Acta neurochirurgica, , Volume: 129, Issue:3-4, 1994
Ex vivo release of eicosanoids after aneurysmal subarachnoid hemorrhage: a preliminary experience in humans.Acta neurologica Scandinavica, , Volume: 86, Issue:2, 1992
A study on cisternal CSF levels of arachidonic acid metabolites after aneurysmal subarachnoid hemorrhage.Journal of the neurological sciences, , Volume: 84, Issue:2-3, 1988
Arachidonic acid metabolism following aneurysm rupture. Evaluation of cerebrospinal fluid and serum concentration of 6-keto-prostaglandin F1 alpha and thromboxane B2 in patients with subarachnoid hemorrhage.Surgical neurology, , Volume: 27, Issue:3, 1987
Cisternal and lumbar CSF levels of arachidonate metabolites after subarachnoid haemorrhage: an assessment of the biochemical hypothesis of vasospasm.Acta neurochirurgica, , Volume: 84, Issue:3-4, 1987
[Arachidonic acid metabolism following aneurysm rupture].European archives of psychiatry and neurological sciences, , Volume: 236, Issue:2, 1986
Arachidonate metabolites and vasospasm after subarachnoid haemorrhage.Neurological research, , Volume: 8, Issue:1, 1986
Prostacyclin and vasospasm in subarachnoid hemorrhage from ruptured intracranial aneurysm. A preliminary clinical study.Acta neurologica Scandinavica, , Volume: 73, Issue:1, 1986
Cisternal and lumbar CSF concentration of arachidonate metabolites in vasospasm following subarachnoid hemorrhage from ruptured aneurysm: biochemical and clinical considerations.Surgical neurology, , Volume: 24, Issue:4, 1985
Relationship between opioids and prostaglandins in hypoxia-induced vasodilation of pial arteries in the newborn pig.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 212, Issue:2, 1996
Prostacyclin (PGI2) protects rat cortical neurons in culture against hypoxia/reoxygenation and glutamate-induced injury.Neuroscience letters, , Sep-17, Volume: 160, Issue:1, 1993
[Prostaglandin levels in the cerebrospinal fluid of newborn infants with neurologic syndromes].Ginekologia polska, , Volume: 59, Issue:7, 1988
A possible role of endogenously formed cerebral prostaglandins in the development of adaptive protection against cerebral hypoxia/ischemia in mice.Methods and findings in experimental and clinical pharmacology, , Volume: 9, Issue:11, 1987
Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage.Thrombosis research, , Volume: 115, Issue:5, 2005
[A further research on physiopathological basis of "Liver Yang Forming Wind Syndrome"].Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, , Aug-28, Volume: 25, Issue:4, 2000
Prostacyclin concentrations and transitional circulation in preterm infants requiring mechanical ventilation.Archives of disease in childhood. Fetal and neonatal edition, , Volume: 80, Issue:1, 1999
Prostanoid and anti-thrombin III levels in premature infants.Advances in experimental medicine and biology, , Volume: 400B, 1997
[Pathophysiological basis of 3 subtypes in ganfeng neidong syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:7, 1993
Eicosanoid levels in CSF of premature infants with posthemorrhagic hydrocephalus.The American journal of the medical sciences, , Volume: 299, Issue:4, 1990
[Prostaglandin levels in the cerebrospinal fluid of newborn infants with neurologic syndromes].Ginekologia polska, , Volume: 59, Issue:7, 1988
[Plasma concentrations of thromboxane B2 and 6-keto-PGF1 alpha in patients with cerebral hemorrhage].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 21, Issue:1, 1988
[Determinations of CSF and plasma concentrations of thromboxane B2 and 6-keto-PGF1 alpha in stroke patients].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 21, Issue:1, 1988
Elevated levels of immunoreactive prostacyclin metabolite in babies who develop intraventricular haemorrhage.Acta paediatrica Scandinavica, , Volume: 76, Issue:1, 1987
Ethamsylate reduces immunoreactive prostacyclin metabolite in low birthweight infants with respiratory distress syndrome.Early human development, , Volume: 14, Issue:3-4, 1986
Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants.The Journal of pediatrics, , Volume: 107, Issue:6, 1985
Dissecting Xuesaitong's mechanisms on preventing stroke based on the microarray and connectivity map.Molecular bioSystems, , Volume: 11, Issue:11, 2015
Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats.Chinese journal of integrative medicine, , Volume: 19, Issue:2, 2013
Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain.The American journal of Chinese medicine, , Volume: 39, Issue:2, 2011
[A further research on physiopathological basis of "Liver Yang Forming Wind Syndrome"].Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, , Aug-28, Volume: 25, Issue:4, 2000
[Exploration on parameters of TCM syndrome in acute cerebral infarction through investigating active factors of vascular endothelium cells].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 20, Issue:12, 2000
[Clinical study on active factors of vascular endothelial cells in acute cerebral infarction patients and therapeutical effect of activating blood stasis].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:7, 1998
[Pathophysiological basis of 3 subtypes in ganfeng neidong syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:7, 1993
Effect of a novel thromboxane A2 receptor antagonist, S-1452, on postischemic brain injury in rats.Stroke, , Volume: 24, Issue:12, 1993
[Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in patients with acute cerebral infarction].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:12, 1991
[Status of the prostacyclin-thromboxane balance in patients with cerebrovascular disorders and the effect of the treatment with nifedipine].Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), , Volume: 91, Issue:7, 1991
[Treatment of acute cerebral infarction with PGI2--evaluating the clinical effect and observation of dynamic changes in plasma TXB2 and 6-keto PGF1 alpha levels].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 24, Issue:3, 1991
[Changes in plasma 6-keto-PGF1 alpha, TXB2 lipid peroxides in acute cerebral infarction patients and the effects of Salvia miltiorrhiza on these three indices].Zhonghua nei ke za zhi, , Volume: 27, Issue:10, 1988
[Determinations of CSF and plasma concentrations of thromboxane B2 and 6-keto-PGF1 alpha in stroke patients].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 21, Issue:1, 1988
The midnight-noon ebb-flow point selection for 30 cases of acute ischemic cerebrovascular diseases.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 28, Issue:3, 2008
Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion.The Journal of nutritional biochemistry, , Volume: 17, Issue:4, 2006
[Effects of effective component from "qing kai ling" on endothelial cell of microvessel in MCAO rats].Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, , Volume: 27, Issue:5, 2004
[Comparison of effect of Astragalus membranaceus and huoxuefang on thromboxane, prostacyclin and adenosine cyclic monophosphate in cerebral reperfusion injury in rabbits].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:3, 1995
[Effects of berberine on platelet aggregation and plasma levels of TXB2 and 6-keto-PGF1 alpha in rats with reversible middle cerebral artery occlusion].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 30, Issue:2, 1995
[Role of arachidonic acid metabolites on development of ischemic cerebral edema in rat middle cerebral artery occlusion].No to shinkei = Brain and nerve, , Volume: 46, Issue:1, 1994
Differential temperature sensitivity of ischemia-induced glutamate release and eicosanoid production in rats.Brain research, , Jul-11, Volume: 650, Issue:2, 1994
Effects of MK-801 and ganglioside GM1 on postischemic prostanoid release and hippocampal lesion in gerbil brain.Acta neurobiologiae experimentalis, , Volume: 54, Issue:4, 1994
Pyrazolopyridine derivative acts as a novel cyclooxygenase inhibitor: antiplatelet effect in aged patients with ischemic stroke.Journal of the American Geriatrics Society, , Volume: 42, Issue:6, 1994
NMDA receptors mediate anoxia/aglycemia-induced release of eicosanoids in immature rat hippocampal slices: utility of an in vitro "ischemic" superfusion model with temporary arrest of medium flow.Folia neuropathologica, , Volume: 32, Issue:3, 1994
Effect of ibuprofen on regional eicosanoid production and neuronal injury after forebrain ischemia in rats.Brain research, , Jun-18, Volume: 614, Issue:1-2, 1993
Transforming growth factor-beta attenuates ischemia-induced alterations in cerebrovascular responses.The American journal of physiology, , Volume: 264, Issue:2 Pt 2, 1993
Superoxide scavengers do not prevent ischemia-induced alteration of cerebral vasodilation in piglets.Pediatric research, , Volume: 33, Issue:2, 1993
Effect of policosanol on cerebral ischemia in Mongolian gerbils: role of prostacyclin and thromboxane A2.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:3, 1993
[The effect of hyperbaric oxygenation on prostaglandin I2 and thromboxane A2 during reperfusion for experimental cerebral ischemia in rabbits].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 25, Issue:1, 1992
Eicosanoid production in the caudate nucleus and dorsal hippocampus after forebrain ischemia: a microdialysis study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 12, Issue:1, 1992
Changes in endogenous prostacyclin in the rat brain during clinical death and after resuscitation.Neuropatologia polska, , Volume: 30, Issue:2, 1992
Studies on eicosanoid metabolism in the fetal rat brain after global ischemia.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21B, 1991
[Effects of Ligusticum wallichii on the plasma levels of beta-thromboglobulin, platelet factor 4, thromboxane B2 and 6-keto-PGF1 alpha in rabbits under acute experimental cerebral ischemia].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:9, 1990
Combination therapy with low-dose aspirin and ticlopidine in cerebral ischemia.Stroke, , Volume: 20, Issue:12, 1989
Prostaglandin profiles in relation to local circulatory changes following focal cerebral ischemia in cats.Stroke, , Volume: 20, Issue:6, 1989
Effect of thromboxane synthase inhibition on eicosanoid levels and blood flow in ischemic rat brain.Stroke, , Volume: 20, Issue:5, 1989
Ischemia alters cerebral vascular responses to hypercapnia and acetylcholine in piglets.Pediatric research, , Volume: 25, Issue:2, 1989
Effects of gangliosides on the formation of eicosanoids in rat brain cerebral ischemia and reperfusion.Pharmacological research communications, , Volume: 20 Suppl 5, 1988
Time course of release in vivo of PGE2, PGF2 alpha, 6-keto-PGF1 alpha, and TxB2 into the brain extracellular space after 15 min of complete global ischemia in the presence and absence of cyclooxygenase inhibition.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 8, Issue:6, 1988
[The effect of glucose and insulin on carbohydrate and prostaglandin metabolism in the ischemic brain].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 21, Issue:6, 1988
A possible role of endogenously formed cerebral prostaglandins in the development of adaptive protection against cerebral hypoxia/ischemia in mice.Methods and findings in experimental and clinical pharmacology, , Volume: 9, Issue:11, 1987
Comparison of the effect of acetylsalicylic acid on platelet function in male and female patients with ischemic stroke.Thrombosis research, , Aug-01, Volume: 47, Issue:3, 1987
Prostanoid concentrations in human CSF following acute ischaemic brain infarction.Clinical and experimental pharmacology & physiology, , Volume: 13, Issue:8, 1986
Lipoxygenase metabolites of arachidonic acid and the development of ischaemic cerebral oedema.Neurological research, , Volume: 8, Issue:1, 1986
Arachidonic acid-induced brain ischaemia: different severity between stroke-resistant spontaneously hypertensive rats and Wistar-Kyoto rats.Journal of hypertension. Supplement : official journal of the International Society of Hypertension, , Volume: 4, Issue:3, 1986
[Effect of bilateral common carotid artery ligation on prostaglandin levels (TXA2, PGI2) in spontaneously hypertensive rats (SHRSP, SHRSR) and normotensive rats (WKY)].No to shinkei = Brain and nerve, , Volume: 38, Issue:6, 1986
[Prostaglandin metabolism in ischemic brain edema].Nihon geka hokan. Archiv fur japanische Chirurgie, , Sep-01, Volume: 54, Issue:5, 1985
Modification of brain vascular eicosanoids after pharmacological treatment and ischemia in the rat: drugs and brain vascular eicosanoids.Cephalalgia : an international journal of headache, , Volume: 5 Suppl 2, 1985
Polyamine and prostaglandin markers in focal cerebral ischemia.Neurosurgery, , Volume: 17, Issue:4, 1985
The effect of incomplete cerebral ischemia on prostaglandin levels in rat brain.Stroke, , Volume: 13, Issue:4
Ibuprofen improves cerebral blood flow after global cerebral ischemia in dogs.Stroke, , Volume: 18, Issue:4
The effect of a thromboxane synthetase inhibitor, OKY-046, on urinary excretion of immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in patients with ischemic cerebrovascular disease.Stroke, , Volume: 16, Issue:2
Postischemic production of eicosanoids in gerbil brain.Stroke, , Volume: 18, Issue:1
Effect of ozagrel on locomotor and motor coordination after transient cerebral ischemia in experimental animal models.Pharmacology, , Volume: 59, Issue:5, 1999
Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto-PGF1 alpha in rat brain during focal cerebral ischemia and reperfusion.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 18, Issue:6, 1997
Microdialysis measurements of PGD2, TXB2 and 6-KETO-PGF1 alpha in rat CA1 hippocampus during transient cerebral ischemia.Prostaglandins, , Volume: 45, Issue:2, 1993
Effect of a novel thromboxane A2 receptor antagonist, S-1452, on postischemic brain injury in rats.Stroke, , Volume: 24, Issue:12, 1993
Ex vivo release of eicosanoids after aneurysmal subarachnoid hemorrhage: a preliminary experience in humans.Acta neurologica Scandinavica, , Volume: 86, Issue:2, 1992
[The study of occurrence mechanism in acute and chronic cerebral vasospasm].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 25, Issue:6, 1992
Effects of ischemia/reperfusion on brain tissue prostanoids and leukotrienes in newborn pigs.Prostaglandins, , Volume: 42, Issue:6, 1991
Anti-lipid peroxidation and protection of ginsenosides against cerebral ischemia-reperfusion injuries in rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 11, Issue:2, 1990
Arachidonic acid metabolite production following focal cerebral ischemia: time course and effect of meclofenamate.Surgical neurology, , Volume: 33, Issue:1, 1990
Prevention of chronic cerebral vasospasm in dogs with ibuprofen and high-dose methylprednisolone.Stroke, , Volume: 20, Issue:8, 1989
Accumulation of arachidonic acid cyclo- and lipoxygenase products in rat brain during ischemia and reperfusion: effects of treatment with GM1-lactone.Journal of neurochemistry, , Volume: 53, Issue:3, 1989
Effects of vasospasm on levels of prostacyclin and thromboxane A2 in cerebral arteries of the monkey.Neurosurgery, , Volume: 22, Issue:1 Pt 1, 1988
Thromboxane synthetase inhibition with imidazole increases blood flow in ischemic penumbra.Neurosurgery, , Volume: 22, Issue:2, 1988
Cisternal and lumbar CSF levels of arachidonate metabolites after subarachnoid haemorrhage: an assessment of the biochemical hypothesis of vasospasm.Acta neurochirurgica, , Volume: 84, Issue:3-4, 1987
Role of arachidonate metabolites in the genesis of cerebral vasospasm.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 17B, 1987
Arachidonic acid metabolism following aneurysm rupture. Evaluation of cerebrospinal fluid and serum concentration of 6-keto-prostaglandin F1 alpha and thromboxane B2 in patients with subarachnoid hemorrhage.Surgical neurology, , Volume: 27, Issue:3, 1987
[Cerebral vasospasm. Clinical and experimental aspects].Minerva medica, , Jun-08, Volume: 77, Issue:24, 1986
Arachidonate metabolites and vasospasm after subarachnoid haemorrhage.Neurological research, , Volume: 8, Issue:1, 1986
[Arachidonic acid metabolism following aneurysm rupture].European archives of psychiatry and neurological sciences, , Volume: 236, Issue:2, 1986
Prostacyclin and vasospasm in subarachnoid hemorrhage from ruptured intracranial aneurysm. A preliminary clinical study.Acta neurologica Scandinavica, , Volume: 73, Issue:1, 1986
Development of cyclooxygenase and lipoxygenase metabolites of arachidonic acid after transient cerebral ischemia.Journal of neurosurgery, , Volume: 64, Issue:1, 1986
Beneficial effect of OKY-046, a selective thromboxane A2 synthetase inhibitor, on experimental cerebral vasospasm.Japanese journal of pharmacology, , Volume: 41, Issue:3, 1986
[Sequential measurements of TxB2 and 6-keto PGF1 alpha in cerebrospinal fluid and serum in patients with subarachnoid hemorrhage].Neurologia medico-chirurgica, , Volume: 26, Issue:4, 1986
Cisternal and lumbar CSF concentration of arachidonate metabolites in vasospasm following subarachnoid hemorrhage from ruptured aneurysm: biochemical and clinical considerations.Surgical neurology, , Volume: 24, Issue:4, 1985
Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 19, Issue:1, 1999
[Research on plasma TXA2, PGI2 levels, blood stasis syndrome and promoting blood circulation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:11, 1995
Pyrazolopyridine derivative acts as a novel cyclooxygenase inhibitor: antiplatelet effect in aged patients with ischemic stroke.Journal of the American Geriatrics Society, , Volume: 42, Issue:6, 1994
Effect of low-dose treatment with perindopril on cardiac function in stroke-prone spontaneously hypertensive rats: role of bradykinin.Journal of cardiovascular pharmacology, , Volume: 24, Issue:3, 1994
Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin.Stroke, , Volume: 23, Issue:10, 1992
Protective effect of cicletanine on hypertension-induced decreases in the renal kallikrein-kinin and prostaglandin systems in stroke-prone spontaneously hypertensive rats.Journal of cardiovascular pharmacology, , Volume: 20, Issue:4, 1992
Changes in endogenous prostacyclin in the rat brain during clinical death and after resuscitation.Neuropatologia polska, , Volume: 30, Issue:2, 1992
[Plasma levels of prostaglandins and leukotrienes in vascular diseases].La Ricerca in clinica e in laboratorio, , Volume: 19 Suppl 1, 1989
Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema.Stroke, , Volume: 19, Issue:3, 1988
Arachidonic acid-induced brain ischaemia: different severity between stroke-resistant spontaneously hypertensive rats and Wistar-Kyoto rats.Journal of hypertension. Supplement : official journal of the International Society of Hypertension, , Volume: 4, Issue:3, 1986
[Mechanisms of changes in the sensitivity of platelets to prostacyclin in patients with cerebrovascular diseases].Voprosy meditsinskoi khimii, , Volume: 34, Issue:6
Synthetic pathways of gallbladder mucosal prostanoids: the role of cyclooxygenase-1 and 2.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 60, Issue:2, 1999
Regulation of eicosanoid synthesis in fibroblasts from inflamed gallbladders.Molecular and cellular endocrinology, , Nov-30, Volume: 115, Issue:1, 1995
Platelet activating factor (PAF) stimulates release of PGI2 from inflamed rabbit gallbladder cell cultures.Prostaglandins, , Volume: 50, Issue:1, 1995
Increased intragallbladder pressure stimulates gallbladder eicosanoid release.Prostaglandins, , Volume: 48, Issue:1, 1994
Acute cholecystitis potentiates bradykinin stimulated fibroblast prostanoid release in the rabbit.Molecular and cellular endocrinology, , Volume: 95, Issue:1-2, 1993
Human cholecystitis is associated with increased gallbladder prostaglandin I2 and prostaglandin E2 synthesis.Hepatology (Baltimore, Md.), , Volume: 16, Issue:5, 1992
Profiling of eicosanoids in inflamed gall bladder wall by gas chromatography with selected-ion monitoring.Journal of chromatography, , Nov-15, Volume: 571, Issue:1-2, 1991
The role of prostanoids in the production of acute acalculous cholecystitis by platelet-activating factor.Annals of surgery, , Volume: 212, Issue:4, 1990
Common bile ligation in the rabbit: an appropriate model for investigating the relationship of endogenous gallbladder prostanoid synthesis with evolving acute inflammation.Prostaglandins, , Volume: 40, Issue:2, 1990
The effects of thromboxane A2 synthetase inhibitor (OKY-046) on complete hepatic ischemia in rats with obstructive jaundice.Surgery today, , Volume: 26, Issue:1, 1996
Tissue eicosanoids and vascular permeability in rats with chronic biliary obstruction.Hepatology (Baltimore, Md.), , Volume: 18, Issue:1, 1993
Role of renal sympathetic nerve activity in renal failure associated with obstructive jaundice in the rat.American journal of surgery, , Volume: 161, Issue:6, 1991
Enhanced production of endogenous prostaglandin in obstructive jaundiced pancreas in dogs.Gastroenterology, , Volume: 98, Issue:5 Pt 1, 1990
Urinary prostaglandins and renal function in obstructive jaundice.Scandinavian journal of gastroenterology, , Volume: 24, Issue:6, 1989
Endotoxin, prostaglandins and renal fibrin deposition in obstructive jaundice.The British journal of surgery, , Volume: 69, Issue:10, 1982
[Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University, , Volume: 30, Issue:6, 2010
Enhanced external counterpulsation improves peripheral artery flow-mediated dilation in patients with chronic angina: a randomized sham-controlled study.Circulation, , Oct-19, Volume: 122, Issue:16, 2010
Synergistic action of famotidine and chlorpheniramine on acetic acid-induced chronic gastric ulcer in rats.World journal of gastroenterology, , Dec-07, Volume: 11, Issue:45, 2005
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs.American journal of physiology. Lung cellular and molecular physiology, , Volume: 284, Issue:2, 2003
[Clinical and experimental study of treatment of nanmiqing capsule for chronic prostatitis].Zhonghua nan ke xue = National journal of andrology, , Volume: 8, Issue:5, 2002
Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension.Cardiovascular research, , Volume: 55, Issue:1, 2002
Arachidonic acid metabolites in antrochoanal polyp and nasal polyp associated with chronic paranasal sinusitis.Acta oto-laryngologica, , Volume: 120, Issue:4, 2000
Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study.American journal of obstetrics and gynecology, , Volume: 177, Issue:6, 1997
Urinary excretion of prostanoids in children with chronic pyelonephritis.Advances in experimental medicine and biology, , Volume: 400B, 1997
Prostacyclin and thromboxane A2 synthesis are increased in acute lower limb ischaemia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 55, Issue:6, 1996
[The clinico-biochemical characteristics of periodontal diseases in subjects who are under conditions of constant, permanent stress].Stomatologiia, , Volume: 75, Issue:1, 1996
Intermittent pneumatic compression in chronic venous insufficiency favorably affects fibrinolytic potential and platelet activation.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, , Volume: 7, Issue:4, 1996
Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction.The American journal of cardiology, , Jun-01, Volume: 73, Issue:15, 1994
Lipid mediator production in acute and chronic pancreatitis in the rat.The Journal of surgical research, , Volume: 56, Issue:1, 1994
Healing of chronic gastric ulcer depends on gastric mucosal prostaglandin synthesis.Hepato-gastroenterology, , Volume: 41, Issue:2, 1994
Chronic gastritis, prostaglandins and Helicobacter pylori.Zeitschrift fur Gastroenterologie, , Volume: 31, Issue:10, 1993
[The functional characteristics of the prostacyclin-thromboxane system in newborn infants with a history of acute and chronic intrauterine hypoxia].Akusherstvo i ginekologiia, , Issue:6, 1993
[The effect of decreased thromboxane synthesis on proliferative glomerulonephritis].Casopis lekaru ceskych, , Oct-18, Volume: 130, Issue:16-17, 1991
Effects of sulindac and naproxen on prostaglandin excretion in patients with impaired renal function and rheumatoid arthritis.The American journal of medicine, , Volume: 89, Issue:3, 1990
[The leukotriene B4 content of the bronchoalveolar lavage fluid and the function of the prostacyclin-thromboxane system in patients with variants of chronic bronchitis].Terapevticheskii arkhiv, , Volume: 62, Issue:4, 1990
[Prostacyclin and thromboxane synthesis in liver tissue in chronic liver diseases].Zeitschrift fur medizinische Laboratoriumsdiagnostik, , Volume: 31, Issue:6, 1990
The relationship of prostaglandins to cAMP, IgG, IgM and alpha-2-macroglobulin in gingival crevicular fluid in chronic adult periodontitis.Archives of oral biology, , Volume: 35, Issue:8, 1990
[The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses].Vestnik dermatologii i venerologii, , Issue:1, 1989
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.Gastroenterology, , Volume: 96, Issue:1, 1989
Effects of chronic fetal hyperinsulinemia on plasma arachidonic acid and prostaglandin concentrations.American journal of obstetrics and gynecology, , Volume: 161, Issue:4, 1989
Peritoneal fluid eicosanoids in chronic pelvic pain.Prostaglandins, , Volume: 38, Issue:4, 1989
[Prostaglandins and chronic proliferative glomerulonephritis].Casopis lekaru ceskych, , Jan-13, Volume: 128, Issue:3, 1989
Prostacyclin and noradrenaline in peripheral nerve of chronic experimental diabetes in rats.Brain : a journal of neurology, , Volume: 112 ( Pt 1), 1989
Prostaglandins in human cholesteatoma and granulation tissue.The American journal of otology, , Volume: 9, Issue:3, 1988
Effects of treadmill and pacing stress testing on peripheral arterial thromboxane, platelet function and catecholamine activities in patients with chronic coronary artery disease.Japanese journal of medicine, , Volume: 26, Issue:1, 1987
[Content of endogenous prostanoids in patients with paroxysmal supraventricular disorders of the heart rhythm].Kardiologiia, , Volume: 26, Issue:6, 1986
Peritoneal fluid prostaglandins and prostanoids in women with endometriosis, chronic pelvic inflammatory disease, and pelvic pain.American journal of obstetrics and gynecology, , Feb-15, Volume: 148, Issue:4, 1984
Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin.The New England journal of medicine, , Feb-02, Volume: 310, Issue:5, 1984
Importance of renal prostaglandins in control of renal function after chronic ligation of the common bile duct in dogs.The Journal of laboratory and clinical medicine, , Volume: 103, Issue:4, 1984
Decrease prostacyclin production: a characteristic of chronic placental insufficiency syndromes.Lancet (London, England), , May-23, Volume: 1, Issue:8230, 1981
Enhanced prostacyclin synthesis in acute human kidney transplant rejection.Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, , Volume: 17, 1980
Enhanced 6-oxo-PGF1 alpha levels in plasma during hemodialysis.Prostaglandins and medicine, , Volume: 5, Issue:6, 1980
Specific neutrophil elastase inhibitor does not attenuate acute lung injury induced by air embolism in awake sheep.Experimental lung research, , Volume: 22, Issue:6
[Prostaglandins content in the blood of newborns with various types of hypoxia].Fiziologicheskii zhurnal, , Volume: 39, Issue:2-3
Release of prostanoids into the portal and hepatic vein in patients with chronic liver disease.Hepatology (Baltimore, Md.), , Volume: 6, Issue:5
Effect of post-treatment with granulocyte colony-stimulating factor on endotoxin-induced lung injury in sheep.Experimental lung research, , Volume: 24, Issue:1
[Tissue levels of 6-ketoprostaglandin Fl alpha and integrity of gastric mucosa in patients with Chagas disease].Arquivos de gastroenterologia, , Volume: 28, Issue:4
Chronic rejection in rat aortic allografts. IV. Effect of hypercholesterolemia in allograft arteriosclerosis.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , Volume: 12, Issue:1 Pt 1
Nicotine inhibits cytokine synthesis by mouse colonic mucosa.European journal of pharmacology, , May-04, Volume: 278, Issue:1, 1995
Species differences in the pattern of eicosanoids produced by inflamed and non-inflamed tissue.Agents and actions, , Volume: Spec No, 1992
Smoking, eicosanoids and ulcerative colitis.The Journal of pharmacy and pharmacology, , Volume: 42, Issue:4, 1990
[Thromboxane analyses in patients with chronic inflammatory bowel diseases].Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, , Volume: 46, Issue:4, 1986
[Arachidonic acid metabolism in inflammatory bowel disease--with reference to cyclooxygenase products].Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, , Volume: 82, Issue:10, 1985
Prostanoid synthesis by cultured peripheral blood mononuclear cells in inflammatory diseases of the bowel.Gastroenterology, , Volume: 82, Issue:4, 1982
Antithrombin reduces reperfusion-induced hepatic metastasis of colon cancer cells.World journal of gastroenterology, , Jan-07, Volume: 12, Issue:1, 2006
Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer.Clinical cancer research : an official journal of the American Association for Cancer Research, , Volume: 7, Issue:11, 2001
Effects of dietary fibre on dimethylhydrazine-induced changes in prostanoid concentrations in rat colonic mucosa.Clinical and experimental pharmacology & physiology, , Volume: 22, Issue:10, 1995
Modulating effect of amount and types of dietary fat on ornithine decarboxylase, tyrosine protein kinase and prostaglandins production during colon carcinogenesis in male F344 rats.Carcinogenesis, , Volume: 14, Issue:7, 1993
Biological half-life of prostacyclin and 6-oxo-PGF1 alpha levels in plasma of patients with colonic cancer.Prostaglandins, leukotrienes, and medicine, , Volume: 22, Issue:3, 1986
PHGPx overexpression induces an increase in COX-2 activity in colon carcinoma cells.Anticancer research, , Volume: 24, Issue:3a
Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics.International journal of molecular medicine, , Volume: 27, Issue:4, 2011
Sickle cell vaso-occlusive crisis is associated with abnormalities in the ratio of vasoconstrictor to vasodilator prostanoids.Pediatric research, , Volume: 38, Issue:1, 1995
[Contents of 6-keto-prostaglandin F1 alpha and thromboxane B2 in the blood of patients with bronchial asthma].Klinicheskaia meditsina, , Volume: 68, Issue:11, 1990
Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog.The American journal of physiology, , Volume: 248, Issue:4 Pt 2, 1985
Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 112, Issue:5, 2012
Interaction between COX-2 G-765C and smoking in relation to coronary artery disease in a Chinese Uighur population.Clinical chemistry and laboratory medicine, , Volume: 49, Issue:1, 2011
Diagnostic biomarkers of essential arterial hypertension: the value of prostacyclin, nitric oxide, oxidized-LDL, and peroxide measurements.International heart journal, , Volume: 50, Issue:3, 2009
NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.Basic research in cardiology, , Volume: 103, Issue:5, 2008
Plasma levels of von willebrand factor, endothelin-1, prostacyclin and thromboxane in children from families with high risk of premature coronary artery disease.Scandinavian journal of clinical and laboratory investigation, , Volume: 61, Issue:4, 2001
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice.Proceedings of the National Academy of Sciences of the United States of America, , Mar-13, Volume: 98, Issue:6, 2001
Free radicals in myocardial injury: experimental and clinical studies.Molecular and cellular biochemistry, , Volume: 111, Issue:1-2, 1992
[Pathogenetic and therapeutic significance of the angioprotective systems in patients with coronary arteriosclerosis].Kardiologiia, , Volume: 30, Issue:12, 1990
Short-term therapy of atherosclerosis with low dose indomethacin: an experimental study.Journal of medical primatology, , Volume: 19, Issue:7, 1990
[Prostaglandins and thromboxane in coronary arteriosclerosis].Kardiologiia, , Volume: 27, Issue:10, 1987
Plasma level of mitochondrial coupling factor 6 increases in patients with coronary heart disease.Circulation journal : official journal of the Japanese Circulation Society, , Volume: 71, Issue:5, 2007
Low dose rofecoxib, inflammation and prostacyclin synthesis in acute coronary syndromes.Roczniki Akademii Medycznej w Bialymstoku (1995), , Volume: 50, 2005
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.Journal of cardiovascular pharmacology, , Volume: 33, Issue:2, 1999
Intravenous aspirin at reperfusion does not reduce infarct size in the dog with a residual critical stenosis.Journal of cardiovascular pharmacology, , Volume: 34, Issue:4, 1999
The effects of endurance training on selected coronary risk factors in children.Acta paediatrica (Oslo, Norway : 1992), , Volume: 87, Issue:4, 1998
Effects of nisoldipine on cytosolic calcium, platelet aggregation, and coagulation/fibrinolysis in patients with coronary artery disease.Angiology, , Volume: 48, Issue:6, 1997
[Study on mechanism of eye-signs in blood stasis syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:4, 1996
Seasonal variation in parameters related to coronary heart disease risk in young men.Atherosclerosis, , Sep-27, Volume: 126, Issue:1, 1996
[Study on relationship of lipid peroxide in coronary heart disease with and without diabetes].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:1, 1996
[Research on plasma TXA2, PGI2 levels, blood stasis syndrome and promoting blood circulation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:11, 1995
Platelet aggregation, coronary artery disease progression and future coronary events.The American journal of cardiology, , Feb-15, Volume: 73, Issue:5, 1994
[Comparison of lipoperoxidative damage in plasma and platelet with the ratio of thromboxane A2 and prostaglandin I2 in blood stasis syndrome with coronary heart disease].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:11, 1993
Type A behavior and alcohol consumption: effects on resting and post-exercise bleeding time thromboxane and prostacyclin metabolites.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 48, Issue:2, 1993
Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking.Journal of the American College of Cardiology, , Volume: 22, Issue:4, 1993
[Changes in TXB2/6-keto-PGF1 alpha ratio and their relation to blood lipids of Type A behavioral patterns].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 24, Issue:4, 1993
Oral cicaprost protects from hypercholesterolaemia-induced impairment of coronary vasodilation.Agents and actions. Supplements, , Volume: 37, 1992
Effects of early angiotensin-converting enzyme inhibition in a pig model of myocardial ischemia and reperfusion.Journal of cardiovascular pharmacology, , Volume: 19, Issue:3, 1992
The effects of testosterone on lipids and eicosanoids in cynomolgus monkeys.Medicine and science in sports and exercise, , Volume: 24, Issue:3, 1992
Cicletanine and reperfusion injury: is there any correlation between arrhythmias, 6-keto-PGF1 alpha, thromboxane B2, and myocardial ion shifts (Na+, K+, Ca2+, and Mg2+) induced by ischemia/reperfusion in isolated rat heart.Journal of cardiovascular pharmacology, , Volume: 17, Issue:4, 1991
[Participation of the prostacyclin-thromboxane system in the mechanisms of prevention of arrhythmia caused by occlusion of the coronary artery in adapted rats].Biulleten' eksperimental'noi biologii i meditsiny, , Volume: 111, Issue:1, 1991
[Relation of coronary heart disease based on traditional Chinese medicine syndrome differentiation and prostaglandin, blood platelet function, and protein C].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:5, 1991
Pacing-induced myocardial ischemia does not affect the endothelial release of coagulant and fibrinolytic factors into the coronary circulation.Clinical cardiology, , Volume: 14, Issue:3, 1991
Low level of prostacyclin as a risk of ischaemic heart disease.International journal of cardiology, , Volume: 30, Issue:2, 1991
Opposite effects of PGI2 and PAF generated during acute myocardial ischemia in the perfused rabbit heart.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21B, 1991
Ridogrel in the setting of percutaneous transluminal coronary angioplasty.The American journal of cardiology, , Aug-15, Volume: 68, Issue:5, 1991
Interactions between nitric oxide and prostacyclin in myocardial ischemia and endothelial cell cultures.Basic research in cardiology, , Volume: 86 Suppl 2, 1991
[Status of the thrombocytic-vascular component of the hemostasis system in the population of the Far North].Vestnik Akademii meditsinskikh nauk SSSR, , Issue:10, 1991
[The relation between coronary diseases and lipid peroxidation].Zhonghua xin xue guan bing za zhi, , Volume: 19, Issue:3, 1991
[Effects of svate on platelet morphology and function in patients with coronary heart disease and hypertension].Zhonghua xin xue guan bing za zhi, , Volume: 19, Issue:3, 1991
Effect of aspirin on local prostaglandin production and serotonin accumulation in a canine model with coronary cyclic flow variations or thrombosis.Journal of molecular and cellular cardiology, , Volume: 23, Issue:4, 1991
Effect of ubiquinone on ischemic arrhythmia in conscious rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 12, Issue:3, 1991
Reduced prostaglandin release from the stunned porcine heart--significance for attenuated reactive hyperaemia.Cardiovascular research, , Volume: 25, Issue:7, 1991
Longitudinal and cross-sectional studies of the relationship between 6-keto PGF1 alpha and high density lipoproteins.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:2, 1990
[Relation of pale tongue, purple tongue and TXA2-PGI2 regulation system].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:4, 1990
Effects of a thromboxane A2 synthetase inhibitor on ventricular fibrillation threshold during coronary artery occlusion and reperfusion.Japanese heart journal, , Volume: 31, Issue:1, 1990
[Responses of plasma eicosanoids and hemodynamics to myocardial ischemia and the salutary effect of calcium entry blocker].Nihon Ika Daigaku zasshi, , Volume: 57, Issue:1, 1990
Coronary endothelium-protective effects of defibrotide in ischaemia and reperfusion.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 341, Issue:3, 1990
Effects of vitamin E on prostacyclin release and lipid composition of the ischemic rat heart.Archives of biochemistry and biophysics, , Volume: 277, Issue:2, 1990
[The effect of eicosapentaenoic acid enriched marine oil on the platelet function in hypercoagulable state].Zhonghua nei ke za zhi, , Volume: 29, Issue:7, 1990
Effects of a low, oral dose of nisoldipine on the systemic and coronary hemodynamics and the prostaglandin metabolism of ischemic heart disease patients.Japanese heart journal, , Volume: 31, Issue:3, 1990
Influence of iloprost on eicosanoid generation and lipid levels in experimental myocardial ischemia in dogs.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 35, Issue:3, 1989
Altered sensitivity to prostacyclin may be involved in the exercise-induced activation of platelets in patients with ischemic heart disease.Progress in clinical and biological research, , Volume: 301, 1989
Ischemia-induced arachidonic acid accumulation and prostanoid release during reperfusion in the isolated rat heart.Progress in clinical and biological research, , Volume: 301, 1989
[Effects of experimental coronary artery stenosis on platelet function].Zhonghua xin xue guan bing za zhi, , Volume: 17, Issue:5, 1989
[Effect of cardiac sympathetic nerves on changes of TXB2 and 6-keto-PGF1 alpha in venous blood of ischemic myocardium].Sheng li xue bao : [Acta physiologica Sinica], , Volume: 41, Issue:1, 1989
Dynamics of prostacyclin and thromboxane during myocardial ischemia.Progress in clinical and biological research, , Volume: 308, 1989
Cardiac ischemia and endothelial function in the isolated rabbit heart.The Journal of surgical research, , Volume: 47, Issue:2, 1989
Effects of peptide 6A on coronary blood flow dynamics in canine coronary thrombosis.Journal of cardiovascular pharmacology, , Volume: 13, Issue:6, 1989
Concentration-dependent effects of purine/xanthine oxidase on release of 6-keto-PGF1 alpha and contractile function of isolated guinea pig hearts: response to "ischemic" conditions followed by reperfusion.Journal of cardiovascular pharmacology, , Volume: 14, Issue:4, 1989
Plasma bradykinin and prostaglandin metabolism and exercise testing in patients with silent myocardial ischemia compared with patients with painful myocardial ischemia.Japanese circulation journal, , Volume: 53, Issue:11, 1989
Effects of cicletanine in the left circumflex coronary artery occlusion-reperfusion canine model of sudden death: analysis of 107 experiments using Cox's proportional hazards model.Drugs under experimental and clinical research, , Volume: 14, Issue:2-3, 1988
Assessment of prostacyclin and thromboxane A2 release during reperfusion after global ischemia induced by crystalloid cardioplegia--comparison between warm and cold ischemia.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, , Volume: 20, Issue:2, 1988
Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosis.The Journal of clinical investigation, , Volume: 82, Issue:5, 1988
Effects of coronary ischemia on lung fluid balance in conscious sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 65, Issue:2, 1988
Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion.American heart journal, , Volume: 115, Issue:3, 1988
Thromboxane B2 and 6-keto-prostaglandin F1 alpha [125I] radioimmunoassays and applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:4, 1988
Effects of iloprost (ZK 36374), a prostacyclin derivative, on platelet function after ischaemic exercise in patients with stable angina pectoris.Thrombosis research, , Oct-15, Volume: 48, Issue:2, 1987
Effect of ovariectomy in humans on serum 6-keto-PGF1 alpha and TXB2 concentrations and platelet fatty acids.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:1, 1987
[A clinical trial of sheng-mai liquor in the treatment of ischemic heart disease].Zhonghua xin xue guan bing za zhi, , Volume: 15, Issue:3, 1987
Regional differences in postischemic recovery in the stunned canine myocardium.American heart journal, , Volume: 114, Issue:5, 1987
[Relation between plasma thromboxane B2 and 6-keto-prostaglandin F1 alpha levels and traditional Chinese medicine in different types of ischemic heart disease patients].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 7, Issue:1, 1987
[Effects of qixue injections on the function of platelets in coronary disease patients].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 7, Issue:1, 1987
Effects of dietary cod liver oil on fatty-acid composition and calcium transport in isolated adult rat ventricular myocytes and on the response of isolated hearts to ischemia and reperfusion.Canadian journal of physiology and pharmacology, , Volume: 65, Issue:2, 1987
[Effect of chuan-xiong granules on platelet aggregation, plasma beta-thromboglobulin, platelet factor IV, thromboxane B2 and 6-keto-prostaglandin F1 alpha in coronary disease patients].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 7, Issue:1, 1987
Effects of treadmill and pacing stress testing on peripheral arterial thromboxane, platelet function and catecholamine activities in patients with chronic coronary artery disease.Japanese journal of medicine, , Volume: 26, Issue:1, 1987
Absence of differential inhibition of thromboxane A2 and prostacyclin by low and high dose aspirin in coronary artery disease.The Canadian journal of cardiology, , Volume: 3, Issue:6, 1987
Effects of a selective thromboxane synthetase inhibitor (OKY-046) in patients with coronary artery disease during exercise.Japanese heart journal, , Volume: 28, Issue:5, 1987
[Status of the prostacyclin and thromboxane system, lipid metabolism and lipid peroxidation processes in patients with coronary atherosclerosis].Vrachebnoe delo, , Issue:4, 1986
[Thromboxane and prostacyclin in patients with stenocardia in induced and spontaneous ischemia of the myocardium].Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, , Volume: 9, Issue:1, 1986
Prostacyclin in the circulation of patients with vascular disorders undergoing surgery.Clinical science (London, England : 1979), , Volume: 71, Issue:6, 1986
Contribution of prostaglandins to reperfusion-induced ventricular failure in isolated rat hearts.The American journal of physiology, , Volume: 251, Issue:1 Pt 2, 1986
[Content of endogenous prostanoids in patients with paroxysmal supraventricular disorders of the heart rhythm].Kardiologiia, , Volume: 26, Issue:6, 1986
[Disorders in the status of the vessel-thrombocyte and plasma links of the hemostatic system in the pathogenesis of disseminated intravascular coagulation in ischemic heart disease].Kardiologiia, , Volume: 26, Issue:9, 1986
[Antagonism of collagen-induced ECG changes in rats by a thromboxane synthetase inhibitor, CV-4151].Nihon yakurigaku zasshi. Folia pharmacologica Japonica, , Volume: 87, Issue:4, 1986
Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain.The American journal of physiology, , Volume: 249, Issue:1 Pt 2, 1985
Cardiac prostaglandin synthesis in spontaneous and in effort angina.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Prostacyclin and thromboxane levels during cardiac ischemia in dogs.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Cyclic blood flow variations induced by platelet-activating factor in stenosed canine coronary arteries despite inhibition of thromboxane synthetase, serotonin receptors, and alpha-adrenergic receptors.Circulation, , Volume: 72, Issue:2, 1985
Plasma thromboxane B2, 6-keto PGF1 alpha and cyclic nucleotides levels as related to treadmill exercise test in patients with ischemic heart disease.Japanese circulation journal, , Volume: 49, Issue:1, 1985
Failure of percutaneous transluminal coronary angioplasty to stimulate platelet and prostaglandin activity.Catheterization and cardiovascular diagnosis, , Volume: 11, Issue:3, 1985
Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery.Thrombosis research, , Aug-15, Volume: 39, Issue:4, 1985
A role for prostaglandins in reperfusion-induced myocardial injury?Advances in myocardiology, , Volume: 6, 1985
Coronary and systemic 6-ketoprostaglandin F1 alpha and thromboxane B2 during myocardial ischemia in dog.The American journal of physiology, , Volume: 248, Issue:4 Pt 2, 1985
Cumulative inhibitory effect of low-dose aspirin on vascular prostacyclin and platelet thromboxane production in patients with atherosclerosis.Circulation, , Volume: 71, Issue:2, 1985
Lack of efficacy of nafazatrom, a novel anti-thrombotic compound, in patients with coronary artery disease.American heart journal, , Volume: 109, Issue:5 Pt 1, 1985
Alteration of prostanoids in atherosclerosis.Seminars in thrombosis and hemostasis, , Volume: 11, Issue:4, 1985
[Endogenous prostacycline and coronaropathy. Plasma levels of 6-keto-PGF1 alpha].Archives des maladies du coeur et des vaisseaux, , Volume: 78, Issue:8, 1985
Effects of selective thromboxane synthetase inhibitor OKY-046 on plasma prostaglandins in patients with coronary artery disease during exercise.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Effects of mild physical exercise on serum lipoproteins and metabolites of arachidonic acid: a controlled randomised trial in middle aged men.British medical journal (Clinical research ed.), , Feb-25, Volume: 288, Issue:6417, 1984
Reduction of prostacyclin synthesis as a possible cause of transient flow reduction in a partially constricted canine coronary artery.Journal of molecular and cellular cardiology, , Volume: 16, Issue:12, 1984
The effects of nafazatrom on arrhythmias and prostanoid release during coronary artery occlusion and reperfusion in anaesthetized greyhounds.Journal of molecular and cellular cardiology, , Volume: 16, Issue:1, 1984
Evidence for isosorbide dinitrate (ISDN) promoting effect on prostacyclin release by the lung and prostacyclin implication in ISDN-induced inhibition of platelet aggregation in humans.Prostaglandins, leukotrienes, and medicine, , Volume: 16, Issue:3, 1984
Cyclic nucleotides, prostaglandins, and ischemic heart disease.Advances in cyclic nucleotide and protein phosphorylation research, , Volume: 17, 1984
Acute systemic and coronary hemodynamic and serologic responses to cigarette smoking in long-term smokers with atherosclerotic coronary artery disease.Journal of the American College of Cardiology, , Volume: 4, Issue:5, 1984
The effects of timolol on arrhythmias and prostanoid release during canine myocardial ischaemia and reperfusion.British journal of pharmacology, , Volume: 81, Issue:4, 1984
Cardioprotective actions of pentoxifylline in an animal model of acute myocardial ischaemia.British journal of pharmacology, , Volume: 81, Issue:4, 1984
Effects of the selective thromboxane synthetase inhibitor dazoxiben on variations in cyclic blood flow in stenosed canine coronary arteries.Circulation, , Volume: 69, Issue:6, 1984
Failure of myocardial ischemia to increase pulmonary microvascular permeability in dogs.Journal of applied physiology: respiratory, environmental and exercise physiology, , Volume: 56, Issue:3, 1984
Effects of vascular trauma and transient myocardial ischaemia on coronary venous prostaglandin levels in the dog.Cardiovascular research, , Volume: 17, Issue:3, 1983
[Cellular mechanism of action of molsidomine. Bioinduction of prostacyclin].Annales de cardiologie et d'angeiologie, , Volume: 32, Issue:8, 1983
Acute effect of cigarette smoking on cardiac prostaglandin synthesis and platelet behavior in patients with coronary heart disease.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Release of adenosine and prostacyclin from ischemic human hearts.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Effects of selective thromboxane synthetase inhibitor and indomethacin on prostacyclin and thromboxane A2 from ischemic canine heart.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
The significance of platelet-vessel wall prostaglandin equilibrium during exercise-induced stress.American heart journal, , Volume: 105, Issue:6, 1983
Release of prostacyclin into the coronary venous blood in patients with coronary arterial disease.Advances in myocardiology, , Volume: 4, 1983
Thromboxane and prostacyclin changes during cardiopulmonary bypass with and without pulsatile flow.The Journal of thoracic and cardiovascular surgery, , Volume: 84, Issue:2, 1982
Prostacyclin from the uterus and woman's cardiovascular advantage.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:5, 1982
Severe intracoronary thromboxane release preceding acute coronary artery occlusion.Prostaglandins, leukotrienes, and medicine, , Volume: 8, Issue:6, 1982
Changes of plasma 6-keto-PGF1 alpha and thromboxane B2 levels and platelet aggregation after tourniquet ischemia on the upper limb in normal subjects and patients with ischemic heart disease.Japanese circulation journal, , Volume: 46, Issue:7, 1982
Effects of trapidil on thromboxane A2-induced aggregation of platelets, ischemic changes in heart and biosynthesis of thromboxane A2.Prostaglandins and medicine, , Volume: 6, Issue:3, 1981
Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias.Nature, , May-28, Volume: 291, Issue:5813, 1981
Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease.The New England journal of medicine, , Mar-19, Volume: 304, Issue:12, 1981
Protective effect of a novel thromboxane synthetase inhibitor, CV-4151, on myocardial damage due to coronary occlusion and reperfusion in the hearts of anesthetized dogs.Journal of cardiovascular pharmacology, , Volume: 8, Issue:4
Laser endarterectomy: a comparison of thrombotic potential following CO2 laser vs surgical endarterectomy.Stroke, , Volume: 17, Issue:2
Effect of the ultrashort-acting beta-blocker Brevibloc on free-radical-mediated injuries during the early reperfusion state.Basic research in cardiology, , Volume: 86, Issue:5
Experimental coronary artery thrombosis in the absence of thromboxane A2 synthesis: evidence for alternate pathways for coronary thrombosis.Journal of cardiovascular pharmacology, , Volume: 7, Issue:1
The effects of dietary mackerel oil on plasma and cell membrane lipids, on hemodynamics and cardiac arrhythmias during recurrent acute ischemia in the pig.Basic research in cardiology, , Volume: 81, Issue:6
Effect of angiotensin II infusion on a prostaglandin I2-metabolite and on left ventricular function.Basic research in cardiology, , Volume: 81, Issue:3
Ent-16β,17-dihydroxy-kauran-19-oic acid, a kaurane diterpene acid from Siegesbeckia pubescens, presents antiplatelet and antithrombotic effects in rats.Phytomedicine : international journal of phytotherapy and phytopharmacology, , Jul-15, Volume: 18, Issue:10, 2011
Beneficial effects of combined thromboxane synthase inhibition/receptor blockade with CGS 22652 in a canine model of coronary thrombosis.European journal of pharmacology, , May-12, Volume: 236, Issue:1, 1993
Effects of Y-20811, a thromboxane A2 synthetase inhibitor, on experimentally induced coronary thrombosis in anesthetized dogs.European journal of pharmacology, , Mar-24, Volume: 213, Issue:2, 1992
[Characteristics of disorders of thrombocytic hemostasis in patients with recurrent myocardial infarction].Kardiologiia, , Volume: 31, Issue:1, 1991
Effect of aspirin on local prostaglandin production and serotonin accumulation in a canine model with coronary cyclic flow variations or thrombosis.Journal of molecular and cellular cardiology, , Volume: 23, Issue:4, 1991
Effects of peptide 6A on coronary blood flow dynamics in canine coronary thrombosis.Journal of cardiovascular pharmacology, , Volume: 13, Issue:6, 1989
Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosis.The Journal of clinical investigation, , Volume: 82, Issue:5, 1988
Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046).American heart journal, , Volume: 112, Issue:4, 1986
Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs.Coronary artery disease, , Volume: 15, Issue:1, 2004
Endothelial cell activation by endotoxin involves superoxide/NO-mediated nitration of prostacyclin synthase and thromboxane receptor stimulation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology, , Volume: 17, Issue:8, 2003
Cyclosporine-induced coronary artery constriction--dissociation between thromboxane release and coronary vasospasm.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , Volume: 18, Issue:4, 1999
Increased serotonin release across the coronary bed during a nonischemic interval in patients with vasospastic angina.Clinical cardiology, , Volume: 19, Issue:6, 1996
Alcohol and coronary spasm.Angiology, , Volume: 45, Issue:3, 1994
Thromboxane release during percutaneous transluminal coronary angioplasty.American heart journal, , Volume: 111, Issue:1, 1986
Development of quantitative analysis of plasma thromboxane B2 by gas chromatography-mass spectrometry.Japanese circulation journal, , Volume: 49, Issue:3, 1985
[Plasma levels of thromboxane B2 and 6-keto PGF1 alpha in patients with variant angina].Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, , Volume: 74, Issue:6, 1985
Coronary spasm, prostaglandin and HLA factors.Japanese circulation journal, , Volume: 49, Issue:1, 1985
[Thromboxane analyses in patients with chronic inflammatory bowel diseases].Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, , Volume: 46, Issue:4, 1986
[Arachidonic acid metabolism in inflammatory bowel disease--with reference to cyclooxygenase products].Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, , Volume: 82, Issue:10, 1985
Imbalance of prostacyclin and thromboxane synthesis in Crohn's disease.Gut, , Volume: 24, Issue:10, 1983
Prostanoid synthesis by cultured peripheral blood mononuclear cells in inflammatory diseases of the bowel.Gastroenterology, , Volume: 82, Issue:4, 1982
Abnormal uterus with polycysts, accumulation of uterine prostaglandins, and reduced fertility in mice heterozygous for acyl-CoA synthetase 4 deficiency.Biochemical and biophysical research communications, , Jun-22, Volume: 284, Issue:4, 2001
Eicosanoids production in endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:4, 1992
Synergistic effect of D-003 and aspirin on experimental thrombosis models.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 68, Issue:5, 2003
Effects of cicletanine in the left circumflex coronary artery occlusion-reperfusion canine model of sudden death: analysis of 107 experiments using Cox's proportional hazards model.Drugs under experimental and clinical research, , Volume: 14, Issue:2-3, 1988
CGS 15435A, a thromboxane synthetase inhibitor with an extended duration of action: a comparison with dazoxiben.European journal of pharmacology, , Jan-20, Volume: 133, Issue:3, 1987
Effects of lipoxygenase inhibitors in arachidonate-induced sudden death.The Journal of pharmacy and pharmacology, , Volume: 36, Issue:3, 1984
Sudden death induced by intracoronary platelet aggregation.Japanese circulation journal, , Volume: 47, Issue:5, 1983
Actions of a protease inhibitor in arachidonate induced sudden death in rabbits.Pharmacological research communications, , Volume: 14, Issue:2, 1982
Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis.European journal of pharmacology, , Nov-28, Volume: 505, Issue:1-3, 2004
[Eicosanoic acid levels in children with atopic dermatitis].Pediatriia, , Issue:10, 1991
Release of mediators from human gastric mucosa and blood in adverse reactions to benzoate.International archives of allergy and applied immunology, , Volume: 96, Issue:2, 1991
[The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses].Vestnik dermatologii i venerologii, , Issue:1, 1989
Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins.The British journal of dermatology, , Volume: 117, Issue:1, 1987
Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice.PloS one, , Volume: 10, Issue:6, 2015
Vasoconstrictor role of cyclooxygenase-1-mediated prostacyclin synthesis in non-insulin-dependent diabetic mice induced by high-fat diet and streptozotocin.American journal of physiology. Heart and circulatory physiology, , Aug-01, Volume: 307, Issue:3, 2014
Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats.Journal of ethnopharmacology, , Nov-25, Volume: 150, Issue:2, 2013
[Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 47, Issue:4, 2012
Treatment of diabetic rats with a peroxynitrite decomposition catalyst prevents induction of renal COX-2.American journal of physiology. Heart and circulatory physiology, , Volume: 300, Issue:3, 2011
Depression of cyclooxygenase-2 induction in aortas of rats with type 1 and type 2 diabetes mellitus.European journal of pharmacology, , Oct-24, Volume: 595, Issue:1-3, 2008
Mechanism underlying enhanced endothelium-dependent vasodilatation in thoracic aorta of early stage streptozotocin-induced diabetic mice.Acta pharmacologica Sinica, , Volume: 24, Issue:5, 2003
Effects of clopidogrel and ticlopidine on experimental diabetic ischemic retinopathy in rats.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 367, Issue:2, 2003
Mechanisms underlying increased release of endothelin-1 from aorta in diabetic rats.Peptides, , Volume: 22, Issue:4, 2001
Effect of DT-TX 30, a combined thromboxane synthase inhibitor and thromboxane receptor antagonist, on retinal vascularity in experimental diabetes mellitus.Thrombosis research, , Feb-01, Volume: 97, Issue:3, 2000
Altered endothelium-dependent and -independent hyperpolarization and endothelium-dependent relaxation in carotid arteries isolated from streptozotocin-induced diabetic rats.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 362, Issue:1, 2000
Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:5, 2000
Effect of dipyridamole on prostanoid production in rat isolated atria.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 60, Issue:2, 1999
Time-course of the alterations in prostanoid production and in contractile responses of mesenteric beds isolated from streptozotocin diabetic rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 60, Issue:4, 1999
High glucose levels modulate eicosanoid production in uterine and placental tissue from non-insulin-dependent diabetic rats during late pregnancy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 58, Issue:6, 1998
Endothelial dysfunction in the perfused kidney from the streptozotocin-induced diabetic rat.Research communications in molecular pathology and pharmacology, , Volume: 96, Issue:1, 1997
Influence of nitric oxide synthase and kinin antagonists on metabolic parameters in chronic streptozotocin-induced diabetes mellitus.Prostaglandins, , Volume: 53, Issue:5, 1997
Eicosanoid production by placental and amnion tissues from control and non-insulin-dependent diabetic rats. Influence of oxytocin in the incubating medium.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:6, 1997
Effect of aspirin plus dipyridamole on the retinal vascular pattern in experimental diabetes mellitus.The Journal of pharmacology and experimental therapeutics, , Volume: 280, Issue:1, 1997
Studies on the impact of dietary fat composition on proteinuria in diabetic rats.Diabetes research and clinical practice, , Volume: 33, Issue:1, 1996
Effects of beraprost sodium and insulin on the electroretinogram, nerve conduction, and nerve blood flow in rats with streptozotocin-induced diabetes.Diabetes, , Volume: 45, Issue:3, 1996
Prostacyclin-thromboxane balance and retinal vascular pattern in rats with experimentally induced diabetes.Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, , Volume: 30, Issue:3, 1995
Eicosanoid production and phospholipase A2 activity in uterine tissue from castrated rats with non-insulin dependent diabetes mellitus.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:5, 1995
Effect of eicosapentaenoic acid ethyl ester on albuminuria in streptozotocin-induced diabetic rats.Journal of nutritional science and vitaminology, , Volume: 40, Issue:1, 1994
Prostanoid production in hypoxic rat isolated atria: influence of acute diabetes.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:4, 1994
Urinary thromboxane and 6-keto-prostaglandin F1 alpha are early markers of acute rejection in experimental pancreas transplantation.Transplantation, , Jul-15, Volume: 58, Issue:1, 1994
Relationship between factors influencing Na(+)-K(+)-ATPase activity and eicosanoid production from 14C-arachidonic acid in spayed rat uterus.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 48, Issue:3, 1993
The effect of aldose reductase inhibitors on glomerular prostaglandin production and urinary albumin excretion in experimental diabetes mellitus.Diabetologia, , Volume: 34, Issue:4, 1991
Effects of a selective thromboxane synthetase inhibitor OKY-046 on experimental diabetic nephropathy.Nephron, , Volume: 56, Issue:3, 1990
Placental thromboxane and prostacyclin production in an ovine diabetic model.American journal of obstetrics and gynecology, , Volume: 163, Issue:6 Pt 1, 1990
Renal vascular responsiveness to arachidonic acid in experimental diabetes.British journal of pharmacology, , Volume: 100, Issue:2, 1990
Influence of an alpha-1-adrenoceptor antagonist, nicergoline, on placental prostanoid production in streptozotocin-induced diabetic pregnant rats.Biology of the neonate, , Volume: 57, Issue:3-4, 1990
Increase in uterine prostaglandin E2, F2 alpha, prostacyclin and stability in thromboxane A2 production during late pregnancy in streptozotocin-induced diabetic rats.Prostaglandins, , Volume: 37, Issue:6, 1989
Prostacyclin and noradrenaline in peripheral nerve of chronic experimental diabetes in rats.Brain : a journal of neurology, , Volume: 112 ( Pt 1), 1989
Prostacyclin and pathogenesis of hemodynamic abnormalities of diabetic ketoacidosis in rats.Diabetes, , Volume: 38, Issue:12, 1989
Role for local prostaglandin and thromboxane production in the regulation of glomerular filtration rate in the rat with streptozocin-induced diabetes.The Journal of laboratory and clinical medicine, , Volume: 113, Issue:6, 1989
The role of oxygen free radicals in preservation injury in pancreas transplantation.Transplantation proceedings, , Volume: 21, Issue:1 Pt 2, 1989
Changes in arachidonic acid metabolite patterns in alloxan-induced diabetic rats.Pharmacology, , Volume: 39, Issue:5, 1989
Sorbinil suppresses glomerular prostaglandin production in the streptozotocin diabetic rat.Metabolism: clinical and experimental, , Volume: 38, Issue:7, 1989
Abnormality in prostacyclin-stimulatory activity in sera from diabetics.Metabolism: clinical and experimental, , Volume: 38, Issue:9, 1989
Appearance of prostaglandins, thromboxane B2, and hepoxilin A3 in the circulation of the normal and diabetic (BB) rat after arachidonic acid administration--correlation with plasma insulin.Biochemistry and cell biology = Biochimie et biologie cellulaire, , Volume: 66, Issue:8, 1988
[Effect of coenzyme A (COA) on the 6-keto-prostaglandin F1 alpha content of the aorta of rats made diabetic with streptozotocin. Potential mechanism of action of its favorable effect on microcirculatory disorders in man].Journal des maladies vasculaires, , Volume: 13, Issue:3, 1988
Pathogenesis of cardiovascular disorders in streptozotocin-induced diabetes in rat. II. Correlation between lipid peroxides, thromboxane A2/prostacyclin, and platelet aggregation in different stages of diabetes.Acta physiologica et pharmacologica Bulgarica, , Volume: 14, Issue:3, 1988
Effects of experimental diabetes on spontaneous contractions, on the output of prostaglandins and on the metabolism of labelled arachidonic acid, in uteri isolated from ovariectomized rats. Influences of estradiol.Prostaglandins, , Volume: 35, Issue:2, 1988
Glomerular prostaglandin production in diabetic rats with renovascular hypertension.Kidney international, , Volume: 33, Issue:6, 1988
Sequential alterations in glomerular prostaglandin and thromboxane synthesis in diabetic rats: relationship to the hyperfiltration of early diabetes.Metabolism: clinical and experimental, , Volume: 36, Issue:1, 1987
Susceptibility of diabetic rat aorta to self-deactivation during prostacyclin synthesis.Prostaglandins, leukotrienes, and medicine, , Volume: 28, Issue:1, 1987
Prostaglandins in experimental pancreatic transplantation.Transplantation proceedings, , Volume: 19, Issue:1 Pt 2, 1987
Effect of dietary cholesterol on the release of prostacyclin from the mesenteric vascular bed in diabetic rat.Diabete & metabolisme, , Volume: 13, Issue:2, 1987
6-Keto-prostaglandin F1 alpha is not added to urine during passage through the rat urinary bladder in vivo.Prostaglandins, , Volume: 32, Issue:2, 1986
The effect of streptozotocin-induced diabetes on PGI2 synthesis by the rat bladder.The Journal of urology, , Volume: 135, Issue:6, 1986
Plasma eicosanoid levels in rats with nonketotic diabetes mellitus: effect of severity.Metabolism: clinical and experimental, , Volume: 35, Issue:4, 1986
Increased release of prostaglandins from the mesenteric vascular bed of diabetic animals: the effects of glucose and insulin.Prostaglandins, leukotrienes, and medicine, , Volume: 24, Issue:2-3, 1986
Are the vascular complications of diabetes mellitus preceded by an altered thromboxane/prostacyclin plasmatic ratio?Medical hypotheses, , Volume: 19, Issue:3, 1986
Altered aortic and cremaster muscle prostaglandin synthesis in diabetic rats.The American journal of physiology, , Volume: 249, Issue:4 Pt 1, 1985
Response of normal and diabetic rat aorta to deendothelialization in terms of 6-keto-prostaglandin F1 alpha synthesis and cholesterol accumulation.Biochemical medicine, , Volume: 33, Issue:1, 1985
Experimental diabetes mellitus inhibits prostacyclin synthesis by the rat penis: pathological implications.Diabetologia, , Volume: 28, Issue:6, 1985
Elevated glucose in vivo and in vitro adversely alters prostaglandin generation in rat aortas and platelets.Prostaglandins, leukotrienes, and medicine, , Volume: 19, Issue:3, 1985
Delayed effects of experimental maternal diabetes on plasma cholesterol level and vascular prostacyclin synthesis in the offspring.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 179, Issue:4, 1985
Plasma prostaglandin levels and circulating fuel levels in rats with diabetic ketoacidosis: effects of cyclooxygenase inhibitors and of alpha and beta adrenergic blockade.Prostaglandins, , Volume: 28, Issue:3, 1984
Prostacyclin, its fatty acid precursor and its metabolites on the inotropic function of and on the prostanoid generation by diabetic arteries.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
Reduced transcoronary exchange and prostaglandin synthesis in diabetic rat heart.The American journal of physiology, , Volume: 247, Issue:4 Pt 2, 1984
Some interrelationships between glucose levels thromboxane production and prostacyclin production in normal and diabetic mice.Prostaglandins, , Volume: 27, Issue:1, 1984
Streptozotocin-induced diabetes in the neonatal rat: effect on plasma lipids and aortic prostaglandin synthesis in adult life.Biochemical medicine, , Volume: 31, Issue:2, 1984
Altered aortic prostaglandin synthesis in a mild form of diabetes and the influence of dietary cholesterol.The Journal of laboratory and clinical medicine, , Volume: 104, Issue:3, 1984
Influence of streptozotocin diabetes on myocardial lipids and prostaglandin release by the rat heart.Biochemical medicine, , Volume: 30, Issue:1, 1983
Renin-angiotensin system and prostacyclin biosynthesis in streptozotocin diabetic rats.European journal of pharmacology, , Oct-14, Volume: 94, Issue:1-2, 1983
Plasma prostaglandin levels in rats with diabetes mellitus and diabetic ketoacidosis.Diabetes, , Volume: 31, Issue:11, 1982
Streptozocin-induced diabetes decreases formation of prostacyclin from arachidonic acid in intact rat lungs.Biochemical medicine, , Volume: 28, Issue:3, 1982
6-Keto-PGF1 alpha synthesis in diabetic rat aorta: effect of substrate concentration and cholesterol feeding.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 171, Issue:3, 1982
Production of 6-oxo-prostaglandin F1alpha by rat aorta: influence of diabetes, insulin treatment, and caloric deprivation.Diabetes, , Volume: 30, Issue:11, 1981
[Effects of docosahexaenoic and eicosapentaenoic acids on the state of metabolites of the prostacyclin I2--thromboxane A2 system in streptozotocin diabetes mellitus].Voprosy pitaniia, , Issue:2
Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats.Pharmacological reports : PR, , Volume: 59, Issue:4
Stimulatory activity on prostacyclin production decreases in sera from streptozotocin-induced diabetic rats.Diabetes research and clinical practice, , Volume: 3, Issue:5
Long-term feeding of corn oil, beef tallow, or menhaden oil and eicosanoid levels in BHE/cdb rats.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 8, Issue:6
Yeast exposure in the preparation of steamed rehmannia root improving its effects on alloxan-induced diabetic rats.Journal of ethnopharmacology, , Nov-25, Volume: 150, Issue:2, 2013
Depression of cyclooxygenase-2 induction in aortas of rats with type 1 and type 2 diabetes mellitus.European journal of pharmacology, , Oct-24, Volume: 595, Issue:1-3, 2008
The hemodynamic abnormalities in short-term insulin deficiency: the role of prostaglandin inhibition.Diabetes, , Volume: 45, Issue:5, 1996
Cyclosporin reduces renal prostanoid excretion in type 1 diabetic patients.Acta diabetologica, , Volume: 29, Issue:1, 1992
Effects of thromboxane synthesis inhibitor triflusal on renal hemodynamics in microalbuminuric diabetic patients.Diabetes care, , Volume: 13, Issue:11, 1990
Stimulation of prostacyclin synthesis by physical exercise in type I diabetes.Diabetes care, , Volume: 12, Issue:9, 1989
Glomerular hyperfiltration and urinary prostaglandins in type 1 diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association, , Volume: 6, Issue:3, 1989
Evidence against a role for prostaglandins in sustaining renal hyperfiltration in type 1 diabetes mellitus.Diabetic medicine : a journal of the British Diabetic Association, , Volume: 6, Issue:6, 1989
Renal hemodynamics and urinary excretion of 6-keto-prostaglandin F1 alpha and thromboxane B2 in newly diagnosed type I diabetic patients.Diabetes, , Volume: 37, Issue:8, 1988
Thromboxane biosynthesis and platelet function in type I diabetes mellitus.The New England journal of medicine, , Jul-28, Volume: 319, Issue:4, 1988
Plasma 6-keto-PGF1 alpha, thromboxane B2 and PGE2 in type 1 (insulin-dependent) diabetic patients during exercise.Diabetologia, , Volume: 30, Issue:7, 1987
Thromboxane and 6-oxo-PGF1 alpha in the plasma of patients with diabetes type I and II.Progress in clinical and biological research, , Volume: 242, 1987
Effects of purified fish oil on platelet lipids and function in diabetic women.Clinica chimica acta; international journal of clinical chemistry, , May-15, Volume: 164, Issue:3, 1987
Plasma prostaglandins: 6-keto-PGF1 alpha, TXB2 and PGE2 in juvenile-onset diabetes determined by high-pressure liquid chromatography and radio-immunoassay.Prostaglandins, leukotrienes, and medicine, , Volume: 22, Issue:3, 1986
Essential fatty acids in diabetes and systemic lupus erythematosus (SLE) patients.Biochemical and biophysical research communications, , Apr-30, Volume: 128, Issue:2, 1985
[Changes in circulatory prostacyclin in diabetics].Zhonghua nei ke za zhi, , Volume: 24, Issue:9, 1985
Influence of glucose, insulin and sera from diabetic patients on the prostacyclin synthesis in vitro in cultured human endothelial cells.Diabetologia, , Volume: 28, Issue:9, 1985
Normal plasma thromboxane B2 (TXB2) and 6-keto-PGF1 alpha levels in childhood diabetes.Prostaglandins, leukotrienes, and medicine, , Volume: 12, Issue:4, 1983
Prostacyclin and thromboxane in diabetic children.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:3, 1983
[The content of stable forms of prostacyclin I2 and thromboxane A2 in the blood plasma in diabetic angiopathies].Problemy endokrinologii, , Volume: 37, Issue:4
Subclinical exocrine pancreatic derangement in human diabetic patients evaluated from pure pancreatic juice.Journal of diabetes and its complications, , Volume: 9, Issue:2
Sperm function and structure and seminal plasma prostanoid concentrations in men with IDDM.Diabetes care, , Volume: 12, Issue:10
No effects of atorvastatin (10 mg/d or 80 mg/d) on nitric oxide, prostacyclin, thromboxane and oxidative stress in type 2 diabetes mellitus patients of the DALI study.Pharmacological research, , Volume: 94, 2015
Vasoconstrictor role of cyclooxygenase-1-mediated prostacyclin synthesis in non-insulin-dependent diabetic mice induced by high-fat diet and streptozotocin.American journal of physiology. Heart and circulatory physiology, , Aug-01, Volume: 307, Issue:3, 2014
Toll-like receptor 4 mutation protects obese mice against endothelial dysfunction by decreasing NADPH oxidase isoforms 1 and 4.Arteriosclerosis, thrombosis, and vascular biology, , Volume: 33, Issue:4, 2013
[Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 47, Issue:4, 2012
Depression of cyclooxygenase-2 induction in aortas of rats with type 1 and type 2 diabetes mellitus.European journal of pharmacology, , Oct-24, Volume: 595, Issue:1-3, 2008
[Relationship between syndrome differentiation of traditional Chinese medicine and vascular endothelial function in patients with diabetic arterial occlusion of lower extremities].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 5, Issue:6, 2007
Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II.Life sciences, , Oct-08, Volume: 75, Issue:21, 2004
[Characteristic changes of vascular tension factors in diabetic arterial occlusion of lower extremities].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 24, Issue:9, 2004
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects.Thrombosis research, , Nov-01, Volume: 108, Issue:2-3, 2002
Comments on "Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications".Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 67, Issue:5, 2002
Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 65, Issue:4, 2001
Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes.Life sciences, , Volume: 66, Issue:5, 2000
Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:5, 2000
High glucose levels modulate eicosanoid production in uterine and placental tissue from non-insulin-dependent diabetic rats during late pregnancy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 58, Issue:6, 1998
Prostanoid production in the umbilicoplacental arterial tree relative to impaired glucose tolerance.Early human development, , Jan-09, Volume: 50, Issue:2, 1998
Effect of gemfibrozil on serum levels of prostacyclin and precursor fatty acids in hyperlipidemic patients with Type 2 diabetes.Diabetes research and clinical practice, , Volume: 42, Issue:3, 1998
Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 59, Issue:5, 1998
Difference in serum-induced prostacyclin production by cultured aortic and capillary endothelial cells.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:1, 1997
Eicosanoid production by placental and amnion tissues from control and non-insulin-dependent diabetic rats. Influence of oxytocin in the incubating medium.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:6, 1997
Elevated renal endothelin-I clearance and mRNA levels associated with albuminuria and nephropathy in non-insulin-dependent diabetes mellitus: studies in obese fa/fa Zucker rats.Clinical science (London, England : 1979), , Volume: 93, Issue:6, 1997
Analysis of the thromboxane/prostacyclin balance in human urine by gas chromatography/selected ion monitoring: abnormalities in diabetics.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 54, Issue:6, 1996
[Study on relationship of lipid peroxide in coronary heart disease with and without diabetes].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:1, 1996
[Effects of tangshenkang capsule on diabetic nephropathy].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:7, 1996
Effect of captopril on renal hemodynamics and renal prostaglandins in early type II diabetic patients with normo-or microalbuminuria.Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, , Volume: 11, Issue:3, 1996
Eicosanoid production and phospholipase A2 activity in uterine tissue from castrated rats with non-insulin dependent diabetes mellitus.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:5, 1995
Improvement in blood flow and diabetic neuropathy by thromboxane A2 dual blocker KDI-792.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:2, 1995
Platelet volume and urinary prostanoid metabolites in non-insulin-dependent diabetes mellitus.Journal of atherosclerosis and thrombosis, , Volume: 1, Issue:2, 1994
Partial purification of serum prostacyclin stimulatory activity by heparin-agarose column; abnormality detected in diabetics.Diabetes research and clinical practice, , Volume: 16, Issue:2, 1992
[The effect of eicosapentaenoic acid enriched marine oil on the platelet function in hypercoagulable state].Zhonghua nei ke za zhi, , Volume: 29, Issue:7, 1990
Effects of captopril on urinary excretion of albumin and prostaglandins in patients with diabetic nephropathy.Diabetes research (Edinburgh, Scotland), , Volume: 13, Issue:3, 1990
Effects of vitamin E administration on platelet function in diabetes mellitus.Diabetes research (Edinburgh, Scotland), , Volume: 14, Issue:1, 1990
Involvement of prostaglandins in the action of captopril in type II diabetic patients.Experimental and clinical endocrinology, , Volume: 93, Issue:1, 1989
Abnormality in prostacyclin-stimulatory activity in sera from diabetics.Metabolism: clinical and experimental, , Volume: 38, Issue:9, 1989
Thromboxane and 6-oxo-PGF1 alpha in the plasma of patients with diabetes type I and II.Progress in clinical and biological research, , Volume: 242, 1987
[Evaluation of plasma 6-keto-prostaglandin F1 alpha and thromboxane B2 in diabetic neuropathy].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 63, Issue:1, 1987
Reduced serum-stimulatory activity on prostacyclin production by cultured aortic endothelial cells in diabetes mellitus.Haemostasis, , Volume: 16, Issue:6, 1986
Platelet and endothelial function tests during metformin treatment in diabetes mellitus (short communication).Hormone and metabolic research. Supplement series, , Volume: 15, 1985
[Changes in circulatory prostacyclin in diabetics].Zhonghua nei ke za zhi, , Volume: 24, Issue:9, 1985
Prostacyclin and thromboxane in non-insulin dependent diabetes: the chlorpropamide alcohol flush reaction revisited.Clinical science (London, England : 1979), , Volume: 67, Issue:6, 1984
Thromboxane, prostacyclin, beta-thromboglobin, and diabetes mellitus.Clinical therapeutics, , Volume: 6, Issue:5, 1984
Effects of cilostazol, a phosphodiesterase inhibitor, on urinary excretion of albumin and prostaglandins in non-insulin-dependent diabetic patients.Diabetes research and clinical practice, , Volume: 22, Issue:1
[The content of stable forms of prostacyclin I2 and thromboxane A2 in the blood plasma in diabetic angiopathies].Problemy endokrinologii, , Volume: 37, Issue:4
Progression of carotid atherosclerosis and the role of endothelin in diabetic patients.Research communications in molecular pathology and pharmacology, , Volume: 108, Issue:1-2
Nitric oxide-cGMP and prostacyclin-cAMP pathways in patients with type II diabetes and different types of retinopathy.Pathophysiology of haemostasis and thrombosis, , Volume: 32, Issue:1
Effects of eicosapentaenoic acid (EPA) on prostacyclin production in diabetics: GC/MS analysis of PGI2 and PGI3 levels.Methods and findings in experimental and clinical pharmacology, , Volume: 19, Issue:6
Subclinical exocrine pancreatic derangement in human diabetic patients evaluated from pure pancreatic juice.Journal of diabetes and its complications, , Volume: 9, Issue:2
Prostaglandins and diabetic nephropathy.Journal of diabetes and its complications, , Volume: 9, Issue:4
Effect of acute thromboxane A2 inhibition on the renal hemodynamics in a spontaneously non-insulin-dependent diabetic rat, Otsuka Long-Evans Tokushima Fatty rat.Journal of diabetes and its complications, , Volume: 13, Issue:4
Long-term feeding of corn oil, beef tallow, or menhaden oil and eicosanoid levels in BHE/cdb rats.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 8, Issue:6
[Relationship between syndrome differentiation of traditional Chinese medicine and vascular endothelial function in patients with diabetic arterial occlusion of lower extremities].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 5, Issue:6, 2007
[Characteristic changes of vascular tension factors in diabetic arterial occlusion of lower extremities].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 24, Issue:9, 2004
Effect of erythrocytes and prostacyclin production in the effect of fructose and sorbitol on platelet activation in human whole blood in vitro.Thrombosis research, , Jun-15, Volume: 86, Issue:6, 1997
Abnormalities in platelets and vascular endothelial cells induced by glycated lipoproteins.Internal medicine (Tokyo, Japan), , Volume: 31, Issue:6, 1992
Effects of vitamin E administration on platelet function in diabetes mellitus.Diabetes research (Edinburgh, Scotland), , Volume: 14, Issue:1, 1990
[Studies on the interrelation of plasma 6-keto-prostaglandin F1 alpha, thromboxane B2 and diabetic microangiopathy].Zhonghua nei ke za zhi, , Volume: 28, Issue:3, 1989
Thromboxane biosynthesis and platelet function in type I diabetes mellitus.The New England journal of medicine, , Jul-28, Volume: 319, Issue:4, 1988
Are the vascular complications of diabetes mellitus preceded by an altered thromboxane/prostacyclin plasmatic ratio?Medical hypotheses, , Volume: 19, Issue:3, 1986
Prostacyclin production reduced in diabetics with vascular complications.Japanese journal of medicine, , Volume: 24, Issue:3, 1985
6-Keto prostaglandin F1 alpha production in endothelial-cell cultures in response to normal and diabetic human serum.Bioscience reports, , Volume: 3, Issue:1, 1983
Prostacyclin and thromboxane in diabetes.British medical journal (Clinical research ed.), , Oct-31, Volume: 283, Issue:6300, 1981
[The content of stable forms of prostacyclin I2 and thromboxane A2 in the blood plasma in diabetic angiopathies].Problemy endokrinologii, , Volume: 37, Issue:4
[Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 1, Issue:2, 2003
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 65, Issue:4, 2001
[Effect of Astragalus injection on platelet function and plasma endothelin in patients with early stage diabetic nephropathy].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 21, Issue:4, 2001
[Comparative study on effect of Panax notoginseng and ticlid in treating early diabetic nephropathy].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:12, 1998
[Effects of tangshenkang capsule on diabetic nephropathy].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:7, 1996
Studies on the impact of dietary fat composition on proteinuria in diabetic rats.Diabetes research and clinical practice, , Volume: 33, Issue:1, 1996
Effect of eicosapentaenoic acid ethyl ester on albuminuria in streptozotocin-induced diabetic rats.Journal of nutritional science and vitaminology, , Volume: 40, Issue:1, 1994
Effects of captopril on urinary excretion of albumin and prostaglandins in patients with diabetic nephropathy.Diabetes research (Edinburgh, Scotland), , Volume: 13, Issue:3, 1990
Effects of a selective thromboxane synthetase inhibitor OKY-046 on experimental diabetic nephropathy.Nephron, , Volume: 56, Issue:3, 1990
Glomerular prostaglandin production in diabetic rats with renovascular hypertension.Kidney international, , Volume: 33, Issue:6, 1988
Glomerular and hormonal responses to dietary protein intake in human renal disease.The American journal of physiology, , Volume: 253, Issue:6 Pt 2, 1987
Prostaglandins and diabetic nephropathy.Journal of diabetes and its complications, , Volume: 9, Issue:4
Effects of cilostazol, a phosphodiesterase inhibitor, on urinary excretion of albumin and prostaglandins in non-insulin-dependent diabetic patients.Diabetes research and clinical practice, , Volume: 22, Issue:1
Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 65, Issue:4, 2001
Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat.The Journal of clinical investigation, , Apr-15, Volume: 97, Issue:8, 1996
Effects of beraprost sodium and insulin on the electroretinogram, nerve conduction, and nerve blood flow in rats with streptozotocin-induced diabetes.Diabetes, , Volume: 45, Issue:3, 1996
Improvement in blood flow and diabetic neuropathy by thromboxane A2 dual blocker KDI-792.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:2, 1995
Hemodynamic effects of cilostazol on peripheral artery in patients with diabetic neuropathy.Arzneimittel-Forschung, , Volume: 42, Issue:4, 1992
Abnormal diurnal urinary sodium and water excretion in diabetic autonomic neuropathy.Clinical science (London, England : 1979), , Volume: 73, Issue:3, 1987
[Evaluation of plasma 6-keto-prostaglandin F1 alpha and thromboxane B2 in diabetic neuropathy].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 63, Issue:1, 1987
Arachidonic Acid-Dependent Pathway Inhibition in Platelets: its Role in Multiple Injury-Induced Coagulopathy and the Potential Mechanisms.Shock (Augusta, Ga.), , 01-01, Volume: 55, Issue:1, 2021
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.Proceedings of the National Academy of Sciences of the United States of America, , 12-08, Volume: 117, Issue:49, 2020
Protective effect of Clinopodium chinense (Benth.) O. Kuntze against abnormal uterine bleeding in female rats.Journal of pharmacological sciences, , Volume: 143, Issue:1, 2020
Cotinine inhibits TLR4/NF-κB signaling pathway and improves deep vein thrombosis in rats.Bioscience reports, , 06-26, Volume: 40, Issue:6, 2020
Maternal vitamin D deficiency increases the thromboxane/prostacyclin ratio through alterations in the one-carbon cycle in Wistar rats.BioFactors (Oxford, England), , Volume: 45, Issue:4, 2019
Mahuang decoction mitigates airway inflammation and regulates IL-21/STAT3 signaling pathway in rat asthma model.Journal of ethnopharmacology, , Oct-05, Volume: 224, 2018
Microvascular pathological features and changes in related injury factors in a rat acute blood stasis model.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 37, Issue:1, 2017
Effects of astaxanthin on blood coagulation, fibrinolysis and platelet aggregation in hyperlipidemic rats.Pharmaceutical biology, , Volume: 55, Issue:1, 2017
Seawater Immersion Aggravates Burn Injury Causing Severe Blood Coagulation Dysfunction.BioMed research international, , Volume: 2016, 2016
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.Journal of pharmacological sciences, , Volume: 130, Issue:2, 2016
Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.Respiratory research, , 08-31, Volume: 17, Issue:1, 2016
Cyclooxygenase-2-Derived Prostaglandins Mediate Cerebral Microcirculation in a Juvenile Ischemic Rat Model.Stroke, , Volume: 47, Issue:12, 2016
Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.Canadian journal of physiology and pharmacology, , Volume: 93, Issue:4, 2015
The antithrombotic effect of RSNK in blood-stasis model rats.Journal of ethnopharmacology, , Sep-15, Volume: 173, 2015
Potential protective effects of Clostridium butyricum on experimental gastric ulcers in mice.World journal of gastroenterology, , Jul-21, Volume: 21, Issue:27, 2015
Prostaglandin D(2) is crucial for seizure suppression and postictal sleep.Experimental neurology, , Volume: 253, 2014
Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis.Journal of ethnopharmacology, , Feb-27, Volume: 152, Issue:1, 2014
[Comparative study on effects of Rubiae Radix et Rhizoma and carbonized Rubiae Radix et Rhizoma on acute blood stasis rat model].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 39, Issue:3, 2014
Effects of danshensu on platelet aggregation and thrombosis: in vivo arteriovenous shunt and venous thrombosis models in rats.PloS one, , Volume: 9, Issue:11, 2014
Toll-like receptor 4 mutation protects obese mice against endothelial dysfunction by decreasing NADPH oxidase isoforms 1 and 4.Arteriosclerosis, thrombosis, and vascular biology, , Volume: 33, Issue:4, 2013
Rosuvastatin in experimental brain trauma: improved capillary patency but no effect on edema or cerebral blood flow.Microvascular research, , Volume: 88, 2013
High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats.Journal of vascular surgery, , Volume: 57, Issue:1, 2013
Dietary fish oil reduces glomerular injury and elevated renal hydroxyeicosatetraenoic acid levels in the JCR:LA-cp rat, a model of the metabolic syndrome.The British journal of nutrition, , Jul-14, Volume: 110, Issue:1, 2013
Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.Chemical & pharmaceutical bulletin, , Volume: 61, Issue:2, 2013
Expression of interleukin-18 in a rat model of deep vein thrombosis.The Journal of cardiovascular surgery, , Volume: 53, Issue:5, 2012
[Study of dahuangzhechong pills on anti-arterial thrombosis with the orthogonal design].Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, , Volume: 35, Issue:1, 2012
Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics.International journal of molecular medicine, , Volume: 27, Issue:4, 2011
[Effect of electroacupuncture at different acupoints on plasma TXB2 and 6-keto-PGF(1alpha), contents in dysmenorrhea rats].Zhen ci yan jiu = Acupuncture research, , Volume: 36, Issue:5, 2011
Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats.Basic research in cardiology, , Volume: 105, Issue:3, 2010
Protective effects of Danshensu on liver injury induced by omethoate in rats.Toxicology mechanisms and methods, , Volume: 20, Issue:8, 2010
Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats.Clinical and experimental hypertension (New York, N.Y. : 1993), , Volume: 32, Issue:7, 2010
Dietary soy protein selectively reduces renal prostanoids and cyclooxygenases in polycystic kidney disease.Experimental biology and medicine (Maywood, N.J.), , Volume: 234, Issue:7, 2009
Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits.American journal of physiology. Heart and circulatory physiology, , Volume: 297, Issue:5, 2009
Pioglitazone protects the myocardium against ischemia-reperfusion injury in eNOS and iNOS knockout mice.American journal of physiology. Heart and circulatory physiology, , Volume: 295, Issue:6, 2008
NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.Basic research in cardiology, , Volume: 103, Issue:5, 2008
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.Journal of hypertension, , Volume: 26, Issue:12, 2008
The role of eNOS, iNOS, and NF-kappaB in upregulation and activation of cyclooxygenase-2 and infarct size reduction by atorvastatin.American journal of physiology. Heart and circulatory physiology, , Volume: 295, Issue:1, 2008
[Development of virulent heat-evil-induced thrombosis animal model].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 33, Issue:18, 2008
Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat.Journal of cardiovascular pharmacology and therapeutics, , Volume: 13, Issue:1, 2008
Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats.Digestive diseases and sciences, , Volume: 52, Issue:2, 2007
Aspirin before reperfusion blunts the infarct size limiting effect of atorvastatin.American journal of physiology. Heart and circulatory physiology, , Volume: 292, Issue:6, 2007
[Effect of the recombinant staphylokinase on pancreatic ischemia in severe acute pancreatitis of rats].Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, , Volume: 19, Issue:8, 2007
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.World journal of gastroenterology, , Oct-14, Volume: 13, Issue:38, 2007
COX-2 mediates morphine-induced delayed cardioprotection via an iNOS-dependent mechanism.Life sciences, , Apr-25, Volume: 78, Issue:22, 2006
Oral treatment and in vitro incubation with fructose modify vascular prostanoid production in the rat.Autonomic & autacoid pharmacology, , Volume: 26, Issue:1, 2006
In vivo endothelial interaction between ACE and COX inhibitors.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 72, Issue:2, 2005
Contribution of capsaicin-sensitive sensory neurons to antithrombin-induced reduction of ischemia/reperfusion-induced liver injury in rats.Thrombosis and haemostasis, , Volume: 93, Issue:1, 2005
Prostacyclin inhibition by indomethacin aggravates hepatic damage and encephalopathy in rats with thioacetamide-induced fulminant hepatic failure.World journal of gastroenterology, , Jan-14, Volume: 11, Issue:2, 2005
Role of sensory neuron in reduction of endotoxin-induced hypotension in rats.Critical care medicine, , Volume: 33, Issue:4, 2005
Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats.Canadian journal of physiology and pharmacology, , Volume: 83, Issue:6, 2005
Antithrombin III pretreatment reduces neutrophil recruitment into the lung and skeletal muscle tissues in the rat model of bilateral lower limb ischemia and reperfusion: a pilot study.Acta anaesthesiologica Scandinavica, , Volume: 49, Issue:8, 2005
Antithrombin reduces the ischemia/reperfusion-induced spinal cord injury in rats by attenuating inflammatory responses.Thrombosis and haemostasis, , Volume: 91, Issue:1, 2004
Functional study of the [Ca2+]i signaling pathway in aortas of L-NAME-hypertensive rats.Pharmacology, , Volume: 70, Issue:3, 2004
Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs.Coronary artery disease, , Volume: 15, Issue:1, 2004
Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness.Journal of virology, , Volume: 78, Issue:19, 2004
Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats.Human gene therapy, , Volume: 15, Issue:12, 2004
Synergistic effect of D-003 and aspirin on experimental thrombosis models.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 68, Issue:5, 2003
Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis.Pharmacological research, , Volume: 48, Issue:1, 2003
Protective effects of CVPM on vascular endothelium in rats fed cholesterol diet.Clinica chimica acta; international journal of clinical chemistry, , Jul-01, Volume: 333, Issue:1, 2003
[The effect of PGI2 on formation and development of hyperdynamic circulatory state in portal hypertensive rats].Zhonghua wai ke za zhi [Chinese journal of surgery], , Volume: 41, Issue:7, 2003
[Correlation between TXB2, 6-Keto-PGF1alpha and liver metastasis in rats model with blood stasis].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 1, Issue:3, 2003
[Effect and mechanism of Tangshenning Recipe on micro-albuminuria in rats with early diabetic nephropathy].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 1, Issue:2, 2003
Distinct role of intrarenal cyclooxygenase-1/2 in chronic unilateral renal ischemia.Nephron, , Volume: 92, Issue:1, 2002
Renal prostacyclin biosynthesis in a baboon model of Shiga toxin mediated hemolytic uremic syndrome.Nephron, , Volume: 92, Issue:2, 2002
Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep.The European respiratory journal, , Volume: 20, Issue:4, 2002
Role of selenium in cytoprotection against cholesterol oxide-induced vascular damage in rats.Atherosclerosis, , Volume: 162, Issue:1, 2002
The effect of cyclooxygenase-2 inhibitor FK3311 on ischemia-reperfusion injury in a canine total hepatic vascular exclusion model.Journal of the American College of Surgeons, , Volume: 192, Issue:1, 2001
Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis.Kidney international, , Volume: 60, Issue:2, 2001
Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:5, 2000
Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.Circulation, , Oct-17, Volume: 102, Issue:16, 2000
Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol.Thrombosis research, , Nov-15, Volume: 100, Issue:4, 2000
Renal production of thromboxane and prostaglandins in a rat model of type 2 diabetes.Life sciences, , Volume: 66, Issue:5, 2000
A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep.Respirology (Carlton, Vic.), , Volume: 4, Issue:2, 1999
Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration.American journal of respiratory and critical care medicine, , Volume: 159, Issue:2, 1999
Antithrombin reduces ischemia/reperfusion injury of rat liver by increasing the hepatic level of prostacyclin.Blood, , Jan-01, Volume: 93, Issue:1, 1999
Endothelin-1 and thromboxane A2 increase pulmonary vascular resistance in granulocyte-mediated lung injury.Critical care medicine, , Volume: 26, Issue:11, 1998
The effects of a thromboxane A2 synthesis inhibitor and a prostaglandin I2 analogue on experimental acute necrotizing pancreatitis in rats.Pancreas, , Volume: 17, Issue:2, 1998
Glomerular thromboxane contributes to pressor response in deoxycorticosterone acetate-salt hypertension.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 58, Issue:2, 1998
Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats.Biology of the neonate, , Volume: 72, Issue:3, 1997
Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses.American journal of veterinary research, , Volume: 58, Issue:11, 1997
Effects of pentoxifylline infusion on response of horses to in vivo challenge exposure with endotoxin.American journal of veterinary research, , Volume: 58, Issue:11, 1997
Ureteral obstruction enhances eicosanoid production in cortical and medullary tubules of rat kidneys.Kidney & blood pressure research, , Volume: 20, Issue:6, 1997
Effect of methylprednisolone on the ulceration, matrix metalloproteinase distribution and eicosanoid production in a model of colitis in the rabbit.International journal of experimental pathology, , Volume: 78, Issue:6, 1997
The influence of heat shock protein 70 induction on hemodynamic variables in a porcine model of recurrent endotoxemia.Shock (Augusta, Ga.), , Volume: 7, Issue:5, 1997
Endothelial dysfunction in the perfused kidney from the streptozotocin-induced diabetic rat.Research communications in molecular pathology and pharmacology, , Volume: 96, Issue:1, 1997
Ischemia/reperfusion injury in the rat colon.Inflammation, , Volume: 21, Issue:2, 1997
The effect of thrombus on the vascular endothelium of arterialized vein grafts.American journal of surgery, , Volume: 172, Issue:2, 1996
Environmental influences on fatty acid composition of membranes from autoimmune MRL lpr/lpr mice.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 54, Issue:4, 1996
Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat.Prostaglandins, , Volume: 52, Issue:1, 1996
Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine.Pharmacology, , Volume: 53, Issue:2, 1996
Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia.Biochemical pharmacology, , Oct-25, Volume: 52, Issue:8, 1996
Adriamycin-related hypertension in pregnant rats: response to a thromboxane receptor antagonist.Clinical science (London, England : 1979), , Volume: 88, Issue:6, 1995
Inhibition of carrageenin-induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2.British journal of pharmacology, , Volume: 114, Issue:3, 1995
Effects of flaxseed and flax oil diets in a rat-5/6 renal ablation model.American journal of kidney diseases : the official journal of the National Kidney Foundation, , Volume: 25, Issue:2, 1995
Protective effects of a novel 32-amino acid C-terminal fragment of CAP18 in endotoxemic pigs.Surgery, , Volume: 117, Issue:6, 1995
Ridogrel improves maternal/fetal homeostasis in an ovine model of pregnancy-induced hypertension.Prostaglandins, , Volume: 47, Issue:3, 1994
[Value of prostaglandins in a pre-eclampsia-equivalent animal model].Zentralblatt fur Gynakologie, , Volume: 116, Issue:5, 1994
Decreased prostacyclin production by liver non-parenchymal cells precedes liver injury in experimental alcoholic liver disease.Life sciences, , Volume: 54, Issue:7, 1994
Cimetidine prevents alcoholic hepatic injury in the intragastric feeding rat model.The Journal of pharmacology and experimental therapeutics, , Volume: 269, Issue:2, 1994
Effect of low-dose treatment with perindopril on cardiac function in stroke-prone spontaneously hypertensive rats: role of bradykinin.Journal of cardiovascular pharmacology, , Volume: 24, Issue:3, 1994
Prostacyclin, thromboxane A2, and atherosclerosis in young hypercholesterolemic swine.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:4, 1994
Capsular type-specific polysaccharide partially inhibits group B Streptococcus-induced pulmonary hypertension.The American review of respiratory disease, , Volume: 148, Issue:1, 1993
Urinary excretion of 6-keto-PGF1 alpha TxB2 and PGE2 in a rat animal model for preeclampsia-like syndrome.Prostaglandins, , Volume: 46, Issue:2, 1993
A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model.Critical care medicine, , Volume: 21, Issue:12, 1993
Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury.The Journal of pharmacology and experimental therapeutics, , Volume: 264, Issue:1, 1993
Effects of early angiotensin-converting enzyme inhibition in a pig model of myocardial ischemia and reperfusion.Journal of cardiovascular pharmacology, , Volume: 19, Issue:3, 1992
Effect of aspirin on the fibrinolytic response in perfused rat hindquarters.European journal of pharmacology, , Dec-08, Volume: 229, Issue:1, 1992
Pentafraction reduces the lung lymph response after endotoxin administration in the ovine model.Circulatory shock, , Volume: 36, Issue:2, 1992
Effects of Y-20811, a thromboxane A2 synthetase inhibitor, on experimentally induced coronary thrombosis in anesthetized dogs.European journal of pharmacology, , Mar-24, Volume: 213, Issue:2, 1992
The effects of testosterone on lipids and eicosanoids in cynomolgus monkeys.Medicine and science in sports and exercise, , Volume: 24, Issue:3, 1992
A comparison of the anti-inflammatory activity of selective 5-lipoxygenase inhibitors with dexamethasone and colchicine in a model of zymosan induced inflammation in the rat knee joint and peritoneal cavity.Agents and actions, , Volume: 32, Issue:3-4, 1991
Effects of thromboxane synthetase inhibition on immune complex glomerulonephritis.American journal of veterinary research, , Volume: 52, Issue:3, 1991
[Plasma PGI2 and TXA2 levels on a model of PDH in leptospirosis].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 22, Issue:3, 1991
[Participation of the prostacyclin-thromboxane system in the mechanisms of prevention of arrhythmia caused by occlusion of the coronary artery in adapted rats].Biulleten' eksperimental'noi biologii i meditsiny, , Volume: 111, Issue:1, 1991
Common bile ligation in the rabbit: an appropriate model for investigating the relationship of endogenous gallbladder prostanoid synthesis with evolving acute inflammation.Prostaglandins, , Volume: 40, Issue:2, 1990
High-dose methylprednisolone and 'ex vivo' release of eicosanoids after experimental subarachnoid haemorrhage.Neurological research, , Volume: 12, Issue:2, 1990
The prominent role of thromboxane A2 formation on early pulmonary hypertension induced by oleic acid administration in sheep.Thrombosis research, , Apr-01, Volume: 58, Issue:1, 1990
Placental thromboxane and prostacyclin production in an ovine diabetic model.American journal of obstetrics and gynecology, , Volume: 163, Issue:6 Pt 1, 1990
The role of thromboxane (TX) A2 in rabbit arterial thrombosis induced by endothelial damage.Thrombosis research, , Jul-01, Volume: 59, Issue:1, 1990
Short-term therapy of atherosclerosis with low dose indomethacin: an experimental study.Journal of medical primatology, , Volume: 19, Issue:7, 1990
Ischemia-reperfusion injury in an ischemic rat liver model: relationship between oxygen-derived free radicals and prostaglandins.Transplantation proceedings, , Volume: 22, Issue:2, 1990
Complement depletion with Naje haje cobra venom factor limits prostaglandin release and improves visceral perfusion in porcine endotoxic shock.The Journal of trauma, , Volume: 29, Issue:8, 1989
Inhibition of thromboxane synthetase accentuates hemodynamic instability and burn edema in the anesthetized sheep model.Surgery, , Volume: 105, Issue:5, 1989
[Experimental animal studies of the effect of selective proximal vagotomy on the prostaglandin content of the gastric mucosa in the Shay ulcer model].Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, , Volume: 22, Issue:1, 1989
Effect of proximal selective vagotomy on gastric prostaglandin content in the Shay-rat ulcer model.Acta physiologica Hungarica, , Volume: 74, Issue:1, 1989
Prostacyclin release and cytotoxicity of peritoneal cells are inversely related in pregnant and non-pregnant mice infected with herpes simplex virus.American journal of reproductive immunology (New York, N.Y. : 1989), , Volume: 20, Issue:4, 1989
Can hemofiltration increase survival time in acute endotoxemia--a porcine shock model.Progress in clinical and biological research, , Volume: 308, 1989
Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited.Annals of surgery, , Volume: 209, Issue:2, 1989
Nonsteroidal anti-inflammatory drugs correct the bactericidal defect of polymorphonuclear leukocytes in a guinea pig model of thermal injury.The Journal of infectious diseases, , Volume: 157, Issue:5, 1988
Changes in oxygen tension and effects on cyclooxygenase metabolites: III. Decrease of retinal prostacyclin in kittens exposed to hyperoxia.Pediatrics, , Volume: 82, Issue:3, 1988
Systemic and regional hemodynamic effects of cyclo-oxygenase and thromboxane synthetase inhibition in normal and hyperdynamic endotoxemic rabbits.Circulatory shock, , Volume: 26, Issue:1, 1988
Inhibition of lipoxygenase (LOX) or of cyclooxygenase (COX) improves survival of rats in endotoxin shock.Biomedica biochimica acta, , Volume: 47, Issue:10-11, 1988
Dexamethasone attenuates reversal of hypertension in one-kidney, one-clip rats.The American journal of physiology, , Volume: 255, Issue:4 Pt 2, 1988
Prostaglandins, leukotrienes, and other arachidonic acid metabolites in the pathogenesis of otitis media.The Laryngoscope, , Volume: 98, Issue:9, 1988
SOD prevents damage and attenuates eicosanoid release in a rabbit model of necrotizing enterocolitis.The American journal of physiology, , Volume: 255, Issue:5 Pt 1, 1988
Longitudinal study of renal prostaglandin excretion in cirrhotic rats: relationship with the renin-aldosterone system.Clinical science (London, England : 1979), , Volume: 75, Issue:3, 1988
Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion.American heart journal, , Volume: 115, Issue:3, 1988
Cardiopulmonary responses after spontaneous inhalation of Douglas fir smoke in goats.The Journal of trauma, , Volume: 28, Issue:2, 1988
The effects of a thromboxane synthase inhibitor, a prostacyclin analog and PGE1 on the nephritis of the NZB/W F1 mouse.Clinical nephrology, , Volume: 28, Issue:6, 1987
Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model.Circulatory shock, , Volume: 21, Issue:3, 1987
Development of equine models of inflammation. The Ciba-Geigy Prize for Research in Animal Health.The Veterinary record, , May-30, Volume: 120, Issue:22, 1987
Platelet deposition on von Willebrand factor-deficient vessels. Extracorporeal perfusion studies in swine with von Willebrand's disease using native and heparinized blood.The Journal of laboratory and clinical medicine, , Volume: 110, Issue:5, 1987
Actions of BW540C in an equine model of acute inflammation: a preliminary study.The veterinary quarterly, , Volume: 9, Issue:2, 1987
The immediate effect of burn wound excision on pulmonary function in sheep: the role of prostanoids, oxygen radicals, and chemoattractants.Surgery, , Volume: 101, Issue:1, 1987
Studies of eicosanoid production in the air pouch model of synovial inflammation.Agents and actions, , Volume: 18, Issue:3-4, 1986
Different excretion pattern of urinary PGE2 and 6-keto-PGF1 alpha in two kidney-one clip Goldblatt rats.Prostaglandins, leukotrienes, and medicine, , Volume: 24, Issue:1, 1986
The essential fatty acid deficient chicken as a model for cystic fibrosis.The American journal of clinical nutrition, , Volume: 44, Issue:6, 1986
Effects of ibuprofen on a pig Pseudomonas ARDS model.The Journal of surgical research, , Volume: 40, Issue:5, 1986
Prostaglandin synthetase inhibition in group B streptococcal shock: hematologic and hemodynamic effects.Pediatric research, , Volume: 20, Issue:9, 1986
Effects of a phenylbutazone paste in ponies: model of acute nonimmune inflammation.American journal of veterinary research, , Volume: 47, Issue:11, 1986
Renal hemodynamic effects of therapeutic plasma levels of sulindac sulfide during hemorrhage.Kidney international, , Volume: 29, Issue:2, 1986
Arachidonate metabolites and vasospasm after subarachnoid haemorrhage.Neurological research, , Volume: 8, Issue:1, 1986
Ibuprofen modifies the inflammatory response of the murine lung to Pseudomonas aeruginosa.European journal of respiratory diseases, , Volume: 67, Issue:2, 1985
The effects of nafazatrom in an acute occlusion-reperfusion model of canine myocardial injury.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 331, Issue:2-3, 1985
Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock.Circulatory shock, , Volume: 17, Issue:1, 1985
Inhibition by AD6 (8-monochloro-3-beta-diethylaminoethyl-4-methyl-7-ethoxycarbonyl methoxy coumarin) of platelet aggregation in dog stenosed coronary artery.Thrombosis research, , Aug-15, Volume: 39, Issue:4, 1985
The development of a model of subacute lung injury after intra-abdominal infection.Surgery, , Volume: 96, Issue:2, 1984
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis.Annals of surgery, , Volume: 200, Issue:5, 1984
Cardioprotective actions of pentoxifylline in an animal model of acute myocardial ischaemia.British journal of pharmacology, , Volume: 81, Issue:4, 1984
Arachidonic acid metabolites in carrageenin-induced equine inflammatory exudate.Journal of veterinary pharmacology and therapeutics, , Volume: 7, Issue:1, 1984
Attenuation of the development of hypertension in spontaneously hypertensive rats by the thromboxane synthetase inhibitor, 4'-(imidazol-1-yl) acetophenone.Prostaglandins, , Volume: 24, Issue:2, 1982
Thromboxane and prostacyclin release from ischaemic myocardium in relation to arrhythmias.Nature, , May-28, Volume: 291, Issue:5813, 1981
The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation.Stroke, , Volume: 31, Issue:6, 2000
Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21A, 1991
Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 67, Issue:5, 1989
Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema.Stroke, , Volume: 19, Issue:3, 1988
Role of activated platelets in endotoxin-induced DIC in rats.Thrombosis research, , Aug-15, Volume: 59, Issue:4, 1990
Hypercoagulable state and hemorrhage in acute leukemias.Chinese medical journal, , Volume: 101, Issue:6, 1988
Mechanism of the therapeutic effect of anisodamine in disseminated intravascular coagulation: study of platelet adhesion and aggregation, malondialdehyde, thromboxane B2, 6-keto-prostaglandin F1 alpha, and microcirculation.Experimental hematology, , Volume: 15, Issue:1, 1987
[Disorders in the status of the vessel-thrombocyte and plasma links of the hemostatic system in the pathogenesis of disseminated intravascular coagulation in ischemic heart disease].Kardiologiia, , Volume: 26, Issue:9, 1986
Implications for thromboxane A2 in the pathogenesis of endotoxic shock.Advances in shock research, , Volume: 6, 1981
Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys.Prostaglandins & other lipid mediators, , Volume: 85, Issue:3-4, 2008
In utero remodeling of the fetal lamb ductus arteriosus: the role of antenatal indomethacin and avascular zone thickness on vasa vasorum proliferation, neointima formation, and cell death.Circulation, , Apr-03, Volume: 103, Issue:13, 2001
Prostacyclin concentrations and transitional circulation in preterm infants requiring mechanical ventilation.Archives of disease in childhood. Fetal and neonatal edition, , Volume: 80, Issue:1, 1999
Distribution of prostacyclin synthase, 6-keto-prostaglandin F1 alpha, and 15-hydroxy-prostaglandin dehydrogenase in the normal and persistent ductus arteriosus of the dog.The American journal of pathology, , Volume: 135, Issue:5, 1989
Endogenous dilator prostaglandins in congenital heart disease.Pediatric cardiology, , Volume: 8, Issue:3, 1987
Early administration of indomethacin to preterm infants.Archives of disease in childhood, , Volume: 61, Issue:3, 1986
Prostaglandins and echocardiography in the assessment of patent ductus arteriosus.Critical care medicine, , Volume: 14, Issue:5, 1986
Prostaglandin levels: predictors of indomethacin responsiveness.Pediatric cardiology, , Volume: 7, Issue:2, 1986
The silent ductus: its precursors and its aftermath.Pediatric cardiology, , Volume: 7, Issue:3, 1986
Systemic production of prostacyclin and thromboxane A2 does not correlate with patency of the ductus arteriosus in very low birth weight infants.The Journal of pediatrics, , Volume: 108, Issue:6, 1986
[New aspects on the pathogenesis of patent ductus arteriosus in premature infants].Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, , Volume: 134, Issue:7, 1986
Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants.The Journal of pediatrics, , Volume: 107, Issue:6, 1985
Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Urinary excretion rates of 6-keto-PGF1 alpha in preterm infants recovering from respiratory distress with and without patent ductus arteriosus.Pediatric research, , Volume: 18, Issue:6, 1984
On the biochemical background of cysteamine-induced duodenal ulceration in the rat.Scandinavian journal of gastroenterology, , Volume: 28, Issue:5, 1993
The effect of prostacyclin and its analogues on cysteamine-induced duodenal ulceration of rats.Scandinavian journal of gastroenterology. Supplement, , Volume: 167, 1989
Potent CNS action of calcitonin to inhibit cysteamine-induced duodenal ulcers in rat.Life sciences, , Aug-03, Volume: 41, Issue:5, 1987
Pathogenic mechanisms involved in mepirizole-induced duodenal damage in the rat.Japanese journal of pharmacology, , Volume: 42, Issue:3, 1986
Role of endogenous gastric prostanoids in the pathogenesis and therapy of duodenal ulcer.Gastroenterology, , Volume: 90, Issue:4, 1986
Effect of cimetidine on human gastric and duodenal prostanoid synthesis.Scandinavian journal of gastroenterology, , Volume: 19, Issue:4, 1984
Prostanoid synthesis by cultured gastric and duodenal mucosa: Possible role in the pathogenesis of duodenal ulcer.Scandinavian journal of gastroenterology, , Volume: 18, Issue:8, 1983
[Effect of electroacupuncture at different acupoints on plasma TXB2 and 6-keto-PGF(1alpha), contents in dysmenorrhea rats].Zhen ci yan jiu = Acupuncture research, , Volume: 36, Issue:5, 2011
[Randomized controlled study on ear-electroacupuncture treatment of endometriosis-induced dysmenorrhea in patients].Zhen ci yan jiu = Acupuncture research, , Volume: 34, Issue:3, 2009
Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea.Prostaglandins & other lipid mediators, , Volume: 83, Issue:1-2, 2007
[Studies on prostaglandin production relating to the mechanism of dysmenorrhea in endometriosis].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 70, Issue:1, 1994
Correlation between dysmenorrheic severity and prostaglandin production in women with endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 46, Issue:2, 1992
Prostaglandins: PGF2 alpha, PGE2, 6-keto-PGF1 alpha and TXB2 serum levels in dysmenorrheic adolescents before, during and after treatment with oral contraceptives.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 36, Issue:3, 1990
Primary dysmenorrhoea: the importance of both prostaglandins E2 and F2 alpha.British journal of obstetrics and gynaecology, , Volume: 90, Issue:12, 1983
Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats.Critical care medicine, , Volume: 34, Issue:7, 2006
[Endothelial cell damage induced in vitro by subeschar tissue fluid].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 15, Issue:5, 1999
Prostaglandin levels of primary bone tumor tissues correlate with peritumoral edema demonstrated by magnetic resonance imaging.Cancer, , Jan-15, Volume: 79, Issue:2, 1997
Modulation by nitric oxide of prostaglandin biosynthesis in the rat.British journal of pharmacology, , Volume: 114, Issue:2, 1995
Inhibition of carrageenin-induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2.British journal of pharmacology, , Volume: 114, Issue:3, 1995
Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat. Differentiation of effects between nabumetone and etodolac.Digestive diseases and sciences, , Volume: 39, Issue:3, 1994
Anti-inflammatory activities of Ph CL28A in rats in vivo.European journal of pharmacology, , Feb-09, Volume: 231, Issue:2, 1993
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.Annals of surgery, , Volume: 212, Issue:6, 1990
Inhibition of thromboxane synthetase accentuates hemodynamic instability and burn edema in the anesthetized sheep model.Surgery, , Volume: 105, Issue:5, 1989
Indomethacin and dexamethasone treatment in experimental neoplastic spinal cord compression: Part 2. Effect on edema and prostaglandin synthesis.Neurosurgery, , Volume: 22, Issue:2, 1988
Topical ibuprofen decreases early postburn edema.Surgery, , Volume: 102, Issue:5, 1987
Thromboxane and 5-HETE increase after experimental spinal cord injury in rabbits.Central nervous system trauma : journal of the American Paralysis Association, , Volume: 4, Issue:2, 1987
Increased thromboxane level in experimental spinal cord injury.Journal of the neurological sciences, , Volume: 74, Issue:2-3, 1986
Platelet-activating factor causes pulmonary vasoconstriction and edema via platelet-independent leukotriene formation.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 12, 1983
Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon.Prostaglandins and medicine, , Volume: 7, Issue:5, 1981
Effects of dibutyryl cAMP on pulmonary air embolism-induced lung injury in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 63, Issue:6, 1987
Effects of thromboxane synthase inhibition on air emboli lung injury in sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:6, 1986
Effect of thromboxane synthetase inhibitors (OKY-046, OKY-1580) on experimentally induced air embolism in anesthetized dogs.Prostaglandins, leukotrienes, and medicine, , Volume: 21, Issue:2, 1986
Specific neutrophil elastase inhibitor does not attenuate acute lung injury induced by air embolism in awake sheep.Experimental lung research, , Volume: 22, Issue:6
Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs.Critical care medicine, , Volume: 25, Issue:7, 1997
Ibuprofen pretreatment does not prevent hemodynamic instability after cemented arthroplasty in dogs.Anesthesia and analgesia, , Volume: 75, Issue:4, 1992
Prostanoid production and pulmonary hypertension after fat embolism are not modified by methylprednisolone.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 38, Issue:5, 1991
Corticosteroids do not inhibit acute pulmonary response to fat embolism.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 37, Issue:4 Pt 2, 1990
A study of the prostaglandin and thromboxane content of the central nervous tissues with the development of chronic relapsing allergic encephalomyelitis.Journal of neuroimmunology, , Volume: 10, Issue:3, 1986
A longitudinal study of the prostaglandin content of central nervous system tissues from guinea pigs with acute experimental allergic encephalomyelitis (EAE).International journal of immunopharmacology, , Volume: 6, Issue:2, 1984
Prostaglandin and thromboxane levels in central nervous system tissues from rats during the induction and development of experimental allergic encephalomyelitis (EAE).Immunopharmacology, , Volume: 7, Issue:2, 1984
Platelets are an unindicted culprit in the development of endometriosis: clinical and experimental evidence.Human reproduction (Oxford, England), , Volume: 30, Issue:4, 2015
[Targeted interruption of COX-2 gene by siRNA inhibits the expression of VEGF, MMP-9, the activity of COX-2 and stimulates the apoptosis in eutopic, ectopic endometrial stromal cells of women with endometriosis].Zhonghua fu chan ke za zhi, , Volume: 50, Issue:10, 2015
[Randomized controlled study on ear-electroacupuncture treatment of endometriosis-induced dysmenorrhea in patients].Zhen ci yan jiu = Acupuncture research, , Volume: 34, Issue:3, 2009
Endometriosis treated by the method of resolving blood stasis to eliminate obstruction in the lower-jiao.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 18, Issue:1, 1998
PGE2 and PGF2 alpha release by human peritoneal macrophages in endometriosis.Prostaglandins, , Volume: 51, Issue:1, 1996
[Studies on prostaglandin production relating to the mechanism of dysmenorrhea in endometriosis].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 70, Issue:1, 1994
Correlation between dysmenorrheic severity and prostaglandin production in women with endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 46, Issue:2, 1992
Eicosanoids production in endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:4, 1992
[Effects of gossypol and GnRHa on the prostaglandins contents of endometriotic cell and in situ].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:9, 1991
Prostaglandin and leukotriene concentration of the peritoneal fluid of endometriosis and other gynecologic disorders in the secretory phase.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Urinary excretion of prostacyclin and thromboxane degradation products in patients with ovarian malignancy: effect of cytostatic treatment.British journal of cancer, , Volume: 60, Issue:5, 1989
Peritoneal fluid eicosanoids in chronic pelvic pain.Prostaglandins, , Volume: 38, Issue:4, 1989
[Prostanoids of the peritoneal fluid and sterility with or without pelvic lesions (endometriosis, postinfectious adhesions)].Pathologie-biologie, , Volume: 34, Issue:2, 1986
Peritoneal fluid volume, estrogen, progesterone, prostaglandin, and epidermal growth factor concentrations in patients with and without endometriosis.Obstetrics and gynecology, , Volume: 68, Issue:2, 1986
Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay.American journal of obstetrics and gynecology, , Volume: 154, Issue:6, 1986
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Peritoneal fluid 6-keto prostaglandin F1 alpha levels in women with endometriosis.American journal of obstetrics and gynecology, , Aug-01, Volume: 152, Issue:7 Pt 1, 1985
Peritoneal fluid prostaglandins and prostanoids in women with endometriosis, chronic pelvic inflammatory disease, and pelvic pain.American journal of obstetrics and gynecology, , Feb-15, Volume: 148, Issue:4, 1984
Peritoneal fluid 6-keto-prostaglandin F1 alpha, thromboxane B2 in endometriosis and unexplained infertility.Acta obstetricia et gynecologica Scandinavica. Supplement, , Volume: 123, 1984
Follicular fluid prostaglandins in endometriosis and ovarian hyperstimulation.Fertility and sterility, , Volume: 41, Issue:1, 1984
Prostaglandins and endometriosis.Acta obstetricia et gynecologica Scandinavica. Supplement, , Volume: 113, 1983
Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis.American journal of obstetrics and gynecology, , Jun-15, Volume: 140, Issue:4, 1981
Fallopian tube prostaglandin production with and without endometriosis.International journal of fertility and menopausal studies, , Volume: 39, Issue:1
Synthesis of prostacyclin and its effect on the contractile activity of the inflamed porcine uterus.Theriogenology, , Volume: 79, Issue:3, 2013
Prostacyclin in endotoxemia-induced acute kidney injury: cyclooxygenase inhibition and renal prostacyclin synthase transgenic mice.American journal of physiology. Renal physiology, , Volume: 293, Issue:4, 2007
Effect of indomethacin on peritoneal protein loss in a rabbit model of peritonitis.Kidney international, , Volume: 59, Issue:1, 2001
The effects of hyperoxia on the biosynthesis of cyclooxygenase products and haemodynamic response to nitric oxide synthase inhibition with L-NAME in endotoxaemic pigs.Journal of veterinary pharmacology and therapeutics, , Volume: 21, Issue:5, 1998
Effect of pentoxifylline, flunixin meglumine, and their combination on a model of endotoxemia in horses.American journal of veterinary research, , Volume: 58, Issue:11, 1997
Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 77, Issue:3, 1994
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model.Critical care medicine, , Volume: 21, Issue:12, 1993
Dietary selenium effects on milk eicosanoid concentration in dairy cows during coliform mastitis.Prostaglandins, , Volume: 42, Issue:4, 1991
[The observation of changes in plasma PGI2 and TXA2 levels and the therapeutic effect of tetramethylpyrazine in E. coli induced acute lung injury in rabbits].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 14, Issue:3, 1991
Ibuprofen therapy in experimental porcine gram-negative septic shock.Resuscitation, , Volume: 22, Issue:1, 1991
Enterococcal sepsis and lung microvascular injury in sheep.Archives of surgery (Chicago, Ill. : 1960), , Volume: 125, Issue:4, 1990
Effect of leukotriene inhibitor LY-171883 on the pulmonary response to Escherichia coli endotoxemia.Critical care medicine, , Volume: 18, Issue:2, 1990
Eicosanoids and the hemodynamic course of live Escherichia coli-induced sepsis in baboons.Circulatory shock, , Volume: 29, Issue:3, 1989
Indomethacin, but not dazoxiben, reduced lung fluid filtration after E. coli infusion.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 64, Issue:6, 1988
Hemodynamics, plasma eicosanoid concentrations, and plasma biochemical changes in calves given multiple injections of Escherichia coli endotoxin.American journal of veterinary research, , Volume: 49, Issue:1, 1988
The pulmonary and systemic response to recurrent endotoxemia in the adult sheep.Surgery, , Volume: 100, Issue:5, 1986
Comparison of the postburn hyperdynamic state and changes in lung function (effect of wound bacterial content).Surgery, , Volume: 100, Issue:5, 1986
The development of a model of subacute lung injury after intra-abdominal infection.Surgery, , Volume: 96, Issue:2, 1984
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis.Annals of surgery, , Volume: 200, Issue:5, 1984
Effects of a fish oil diet on pigs' cardiopulmonary response to bacteremia.JPEN. Journal of parenteral and enteral nutrition, , Volume: 15, Issue:2
[A trial of low-dose aspirin therapy in high-risk pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:7, 1992
Mid-trimester pregnancy--a time of tranquility or activity?British journal of obstetrics and gynaecology, , Volume: 91, Issue:6, 1984
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Uterine prostaglandin concentrations following fetal death in sheep.Prostaglandins, , Volume: 23, Issue:3, 1982
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy.Prostaglandins & other lipid mediators, , Volume: 95, Issue:1-4, 2011
Vasoactive mediator release by fetal endothelial cells in intrauterine growth restriction and preeclampsia.American journal of obstetrics and gynecology, , Volume: 184, Issue:3, 2001
[Study on relativity between oxygen free radical and thromboxane B2, 6-keto-PGF1 alpha during ligustrazine treatment of intrauterine growth retardation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:5, 1998
Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats.Biology of the neonate, , Volume: 72, Issue:3, 1997
Release of vasoactive agents during cordocentesis: differences between normally grown and growth-restricted fetuses.American journal of obstetrics and gynecology, , Volume: 175, Issue:3 Pt 1, 1996
[Effect of trapidil in prevention of pre-eclampsia and fetal retardation].Zentralblatt fur Gynakologie, , Volume: 117, Issue:1, 1995
Lack of association between Doppler velocimetry and synthesis of prostacyclin and thromboxane in umbilical cord vessels from growth retarded fetuses.Acta obstetricia et gynecologica Scandinavica, , Volume: 74, Issue:2, 1995
[Effect of 3,4-dihydroxyacetophenone treatment on intrauterine growth retardation].Zhonghua fu chan ke za zhi, , Volume: 28, Issue:6, 1993
Endotoxin-induced fetal growth retardation in the pregnant guinea pig.American journal of obstetrics and gynecology, , Volume: 168, Issue:2, 1993
[A trial of low-dose aspirin therapy in high-risk pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:7, 1992
Evidence that prostacyclin deficiency is a specific feature in preeclampsia.American journal of obstetrics and gynecology, , Mar-15, Volume: 148, Issue:6, 1984
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
Effect of IGF-I on placental thromboxane and prostacyclin release in severe intrauterine growth retardation.The Journal of maternal-fetal medicine, , Volume: 6, Issue:6
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.Journal of pharmacological sciences, , Volume: 130, Issue:2, 2016
Salicylate treatment in Kawasaki disease: high dose or low dose?European journal of pediatrics, , Volume: 150, Issue:9, 1991
Ibuprofen prevents Pasteurella hemolytica endotoxin-induced changes in plasma prostanoids and serotonin, and fever in sheep.Journal of veterinary pharmacology and therapeutics, , Volume: 8, Issue:4, 1985
Trans-10,cis-12-conjugated linoleic acid worsens renal pathology and alters cyclooxygenase derived oxylipins in obesity-associated nephropathy.The Journal of nutritional biochemistry, , Volume: 26, Issue:2, 2015
Prostaglandins in squamous cell carcinoma of the larynx: tumor and peritumor synthesis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Acute effect of paraquat on lung fluid balance and prostanoid production in awake sheep.The American review of respiratory disease, , Volume: 134, Issue:6, 1986
Prostaglandin release and altered microvascular integrity after burn injury.The Journal of surgical research, , Volume: 31, Issue:4, 1981
Effect of post-treatment with granulocyte colony-stimulating factor on endotoxin-induced lung injury in sheep.Experimental lung research, , Volume: 24, Issue:1
Specific neutrophil elastase inhibitor does not attenuate acute lung injury induced by air embolism in awake sheep.Experimental lung research, , Volume: 22, Issue:6
Pulmonary hypertensive response to foreign body microemboli.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:2, 1990
Compound polyglactin 910/polypropylene small vessel prostheses.Journal of vascular surgery, , Volume: 5, Issue:4, 1987
Dacron inhibition of arterial regenerative activities.Journal of vascular surgery, , Volume: 3, Issue:5, 1986
Eicosanoids and inflammatory cells in frostbitten tissue: prostacyclin, thromboxane, polymorphonuclear leukocytes, and mast cells.Plastic and reconstructive surgery, , Volume: 101, Issue:7, 1998
Defibrotide activity in experimental frostbite injury.British journal of plastic surgery, , Volume: 51, Issue:6, 1998
[The adaptive changes in vascular endothelial cell and resistance to frostbite in cold acclimated rats].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 13, Issue:3, 1997
Synthetic pathways of gallbladder mucosal prostanoids: the role of cyclooxygenase-1 and 2.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 60, Issue:2, 1999
[Measurement of prostaglandins in human bile juice].Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, , Volume: 81, Issue:9, 1984
Prostaglandin and leukotriene concentration of the peritoneal fluid of endometriosis and other gynecologic disorders in the secretory phase.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Peritoneal fluid eicosanoids in chronic pelvic pain.Prostaglandins, , Volume: 38, Issue:4, 1989
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Prostacyclin and hormone levels in patients with symptoms of miscarriage and infection.Medicinski pregled, , Volume: 55, Issue:9-10
C-reactive protein and 6-keto prostaglandin F 1-alpha in patients with gynecologic cancer.Gynecologic oncology, , Volume: 36, Issue:2, 1990
Urinary 6-keto-prostaglandin F1a in patients with gynaecological tumours.Cancer letters, , Volume: 34, Issue:2, 1987
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Peripheral plasma immunoreactive 6-oxo-prostaglandin F1 alpha and gynaecological tumours.British journal of cancer, , Volume: 45, Issue:3, 1982
Glioma prostaglandin levels correlate with brain edema.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 18, Issue:2, 1998
Production of prostaglandins and thromboxane by isolated cells from intracranial tumours.Journal of neurology, neurosurgery, and psychiatry, , Volume: 47, Issue:6, 1984
Different effect of cyclosporine A and mycophenolate mofetil on passive Heymann nephritis in the rat.Nephron. Experimental nephrology, , Volume: 100, Issue:2, 2005
Inhibitory effects of ligustrazine, a modulator of thromboxane-prostacycline-nitric oxide balance, on renal injury in rats with passive Heyman nephritis.Nephron. Physiology, , Volume: 98, Issue:3, 2004
Effect of DP-1904, a thromboxane A2 synthase inhibitor, on passive Heymann nephritis in rats.European journal of pharmacology, , Nov-28, Volume: 316, Issue:1, 1996
[Changes in renal cortical thromboxane A2, prostaglandin F1 alpha and effects of dazoxiben, chuan xiong on in situ immune complex glomerulonephritis in rats].Zhonghua yi xue za zhi, , Volume: 73, Issue:9, 1993
Interleukin 4 downregulates cell growth and prostaglandin release of human mesangial cells.Biochemical and biophysical research communications, , Dec-15, Volume: 197, Issue:2, 1993
[Clinical and experimental study on effects of ji shen mixture for infantile acute glomerulonephritis].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:12, 1993
[The effect of decreased thromboxane synthesis on proliferative glomerulonephritis].Casopis lekaru ceskych, , Oct-18, Volume: 130, Issue:16-17, 1991
Synthesis and biological evaluation of 2,3,5-trimethyl-6-(3-pyridylmethyl)-1,4-benzoquinone (CV-6504), a dual inhibitor of TXA2 synthase and 5-lipoxygenase with scavenging activity of active oxygen species (AOS).Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21A, 1991
Effects of thromboxane synthetase inhibition on immune complex glomerulonephritis.American journal of veterinary research, , Volume: 52, Issue:3, 1991
Clinical effects of selective thromboxane A2 synthetase inhibitor in patients with nephrotic syndrome.Clinical nephrology, , Volume: 30, Issue:5, 1988
Glomerular and hormonal responses to dietary protein intake in human renal disease.The American journal of physiology, , Volume: 253, Issue:6 Pt 2, 1987
[Measurement of urinary TXB2, 6-keto-PGF1 alpha by radioimmunoassay and its clinical significance].Zhonghua nei ke za zhi, , Volume: 26, Issue:12, 1987
Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor.Prostaglandins, leukotrienes, and medicine, , Volume: 27, Issue:2-3, 1987
Effect of a thromboxane synthetase inhibitor on eicosanoid synthesis and glomerular injury during acute unilateral glomerulonephritis in the rat.Clinical nephrology, , Volume: 26, Issue:4, 1986
Indomethacin blunts the orthostatic increase in plasma aldosterone in glomerulonephritis.The Journal of clinical endocrinology and metabolism, , Volume: 59, Issue:2, 1984
Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin.The New England journal of medicine, , Feb-02, Volume: 310, Issue:5, 1984
Urinary excretion of prostaglandin F2 alpha and 6-keto-prostaglandin F1 alpha during volume expansion in patients with glomerulonephritis.Acta medica Scandinavica, , Volume: 212, Issue:5, 1982
Prostacyclin and thromboxane in chronic uremia: effect of hemodialysis.Clinical nephrology, , Volume: 18, Issue:2, 1982
Evaluation of a polyester collagen-coated heparin bonded vascular graft.The Journal of cardiovascular surgery, , Volume: 38, Issue:1, 1997
The effect of thrombus on the vascular endothelium of arterialized vein grafts.American journal of surgery, , Volume: 172, Issue:2, 1996
Recovery of endothelial cells and prostanoid production in endothelial cell-seeded grafts.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, , Volume: 12, Issue:1, 1996
The effect of platelet inhibitory therapy on graft thromboresistance.International journal of experimental pathology, , Volume: 74, Issue:5, 1993
Endothelial cell seeding improves 4 mm PTFE vascular graft performance in antiplatelet medicated dogs.Artery, , Volume: 14, Issue:3, 1987
Compound polyglactin 910/polypropylene small vessel prostheses.Journal of vascular surgery, , Volume: 5, Issue:4, 1987
Prostacyclin production by internal mammary artery as a factor in coronary artery bypass grafts.Surgery, , Volume: 100, Issue:2, 1986
The natural history of endothelial structure and function in arterialized vein grafts.Journal of vascular surgery, , Volume: 3, Issue:2, 1986
Adverse effects of high dose aspirin on platelet adhesion to experimental autogenous vein grafts.Cardiovascular research, , Volume: 19, Issue:12, 1985
Correlation between the effects of aspirin and dipyridamole on platelet function and prevention of intimal hyperplasia in autologous vein grafts.The Canadian journal of cardiology, , Volume: 4, Issue:1
Prostacyclin production by blood-contacting surfaces of endothelialized vascular prostheses.The Journal of cardiovascular surgery, , Volume: 31, Issue:5
Arachidonic acid, an in vivo inhibitor of carrageenin induced granulomas in the rat.European journal of pharmacology, , Apr-16, Volume: 110, Issue:3, 1985
Prostaglandin production by minced carrageenin granuloma tissue of rats and its inhibition by dexamethasone and cycloheximide.Prostaglandins and medicine, , Volume: 5, Issue:4, 1980
Quantitative determination of 6-keto prostaglandin F1 alpha in biological fluids by capillary gas chromatography-chemical ionization mass spectrometry.Journal of chromatography, , Dec-12, Volume: 221, Issue:2, 1980
Prostaglandins E2, F2 alpha, 6-keto-F1 alpha and thromboxane B2 levels in carrageenin-induced inflammatory exudates in the rat air-pouch granuloma.Prostaglandins and medicine, , Volume: 2, Issue:4, 1979
Inhibition of tumor metastasis by carrageenan-induced granulomas.Clinical & experimental metastasis, , Volume: 7, Issue:1
Circulating prostacyclin and thromboxane in patients with Graves' disease.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:1, 1987
Differences in prostaglandin E2, prostaglandin F2 alpha and prostacyclin contents and their response to thyrotrophin stimulation and in prostaglandin-stimulated cyclic AMP response in normal and Grave's thyroid slices.The Journal of endocrinology, , Volume: 98, Issue:3, 1983
Head injury induces increased prostaglandin synthesis in rat brain.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 7, Issue:1, 1987
Thromboxane and prostacyclin in clinical acute respiratory failure.The Journal of surgical research, , Volume: 39, Issue:1, 1985
GC/MS analysis of prostaglandins in ventricular cerebrospinal fluid from head injured humans.Prostaglandins and medicine, , Volume: 7, Issue:2, 1981
Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin.American journal of medical genetics. Part A, , Volume: 152A, Issue:8, 2010
Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease.Circulation, , Volume: 88, Issue:5 Pt 1, 1993
Abnormalities in the biosynthesis of thromboxane A2 and prostacyclin in children with cyanotic congenital heart disease.British heart journal, , Volume: 69, Issue:2, 1993
Endogenous dilator prostaglandins in congenital heart disease.Pediatric cardiology, , Volume: 8, Issue:3, 1987
[Thromboxane-prostacyclin balance and platelet aggregability in patients with minor cardiac abnormalities].Terapevticheskii arkhiv, , Volume: 82, Issue:9, 2010
Selective thromboxane A2 synthase inhibition by OKY-046 prevents cardiopulmonary dysfunction after ovine smoke inhalation injury.Anesthesiology, , Volume: 102, Issue:5, 2005
Experimental study on microthrombi and myocardial injuries.Microvascular research, , Volume: 51, Issue:1, 1996
CGS 8515 and indomethacin attenuate cytokine-induced cardiopulmonary dysfunction in pigs.The American journal of physiology, , Volume: 264, Issue:4 Pt 2, 1993
Free radicals in myocardial injury: experimental and clinical studies.Molecular and cellular biochemistry, , Volume: 111, Issue:1-2, 1992
Biosynthesis of TXB2 and 6-oxo-PGF1 alpha in the heart and other tissues under pathophysiological conditions.Agents and actions. Supplements, , Volume: 37, 1992
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.Annals of surgery, , Volume: 212, Issue:6, 1990
[Changes in plasma TXB2 and 6-keto-PGF1 alpha and left atrial thrombosis in mitral stenosis].Zhonghua xin xue guan bing za zhi, , Volume: 18, Issue:2, 1990
[Plasma levels of prostaglandins and leukotrienes in vascular diseases].La Ricerca in clinica e in laboratorio, , Volume: 19 Suppl 1, 1989
[Clinical study of prostaglandin (PG) metabolism during extracorporeal circulation].[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, , Volume: 36, Issue:12, 1988
[Comparison of centrifugal pump (bio pump) with roller pump: clinical study].Kyobu geka. The Japanese journal of thoracic surgery, , Volume: 37, Issue:13, 1984
NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.Basic research in cardiology, , Volume: 103, Issue:5, 2008
Loop diuretics enhance the secretion of prostacyclin in vitro, in healthy persons, and in patients with chronic heart failure.European journal of clinical pharmacology, , Volume: 55, Issue:2, 1999
Hemodynamic and neurohumoral responses to exercise in patients with congestive heart failure.Japanese circulation journal, , Volume: 57, Issue:5, 1993
Effects of sustained ligustrazine on hemorrheology in patients with chronic pulmonary heart disease.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:3, 1992
[Pharmacological correction by roxicam of the prostacyclin-thromboxane system in acute myocardial infarction complicated by heart failure].Kardiologiia, , Volume: 31, Issue:8, 1991
[Piretanide in chronic and acute decompensated heart failure. Effect on hemodynamics and vasoactive hormones].Medizinische Klinik (Munich, Germany : 1983), , Jun-15, Volume: 84, Issue:6, 1989
Peripheral hemodynamic effects of captopril in patients with congestive heart failure.American heart journal, , Volume: 117, Issue:1, 1989
Effects of rhein on renal arachidonic acid metabolism and renal function in patients with congestive heart failure.European journal of clinical pharmacology, , Volume: 37, Issue:1, 1989
A double blind comparison of naproxen and sulindac in female patients with heart failure.Scandinavian journal of rheumatology. Supplement, , Volume: 62, 1986
Cardiovascular prostaglandins: some comments on their involvement in circulatory physiology and pathophysiology.Acta medica Scandinavica. Supplementum, , Volume: 707, 1986
Hemodynamic changes and renal plasma flow in early heart failure: implications for renin, aldosterone, norepinephrine, atrial natriuretic peptide and prostacyclin.Basic research in cardiology, , Volume: 82, Issue:2
Increased myocardial release of prostacyclin in dogs with heart failure.Journal of cardiovascular pharmacology, , Volume: 5, Issue:2
Renal prostacyclin biosynthesis in a baboon model of Shiga toxin mediated hemolytic uremic syndrome.Nephron, , Volume: 92, Issue:2, 2002
Prostacyclin in diarrhoea-associated haemolytic uraemic syndrome.Pediatric nephrology (Berlin, Germany), , Volume: 7, Issue:5, 1993
Prostacyclin concentrations in haemolytic uraemic syndrome after acute shigellosis in children.Archives of disease in childhood, , Volume: 66, Issue:10, 1991
Absence of plasma prostacyclin stimulating activity deficiency in hemolytic uremic syndrome.The Journal of pediatrics, , Volume: 111, Issue:1, 1987
6-keto-PGF1 alpha levels and prostacyclin therapy in 2 adult patients with hemolytic-uremic syndrome.Clinical nephrology, , Volume: 26, Issue:3, 1986
In vitro prostacyclin production in the hemolytic-uremic syndrome.The Western journal of medicine, , Volume: 144, Issue:2, 1986
Prostanoids in hemolytic uremic syndrome.The Journal of pediatrics, , Volume: 106, Issue:6, 1985
Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure.Thrombosis research, , Apr-01, Volume: 30, Issue:1, 1983
Prostacyclin and haemolytic, thrombocytopenic microangiopathy.Lancet (London, England), , Sep-05, Volume: 2, Issue:8245, 1981
Ent-16β,17-dihydroxy-kauran-19-oic acid, a kaurane diterpene acid from Siegesbeckia pubescens, presents antiplatelet and antithrombotic effects in rats.Phytomedicine : international journal of phytotherapy and phytopharmacology, , Jul-15, Volume: 18, Issue:10, 2011
Early inflammatory response correlates with the severity of injury.Critical care medicine, , Volume: 24, Issue:7, 1996
Cyclooxygenase and lipoxygenase metabolism in sodium taurocholate induced acute hemorrhagic pancreatitis in rats.Prostaglandins, , Volume: 45, Issue:4, 1993
Exaggerated splanchnic PGI2 release following acute hemorrhage is due to new protein synthesis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 48, Issue:3, 1993
[Plasma PGI2 and TXA2 levels on a model of PDH in leptospirosis].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 22, Issue:3, 1991
Ridogrel in the setting of percutaneous transluminal coronary angioplasty.The American journal of cardiology, , Aug-15, Volume: 68, Issue:5, 1991
Combination therapy with low-dose aspirin and ticlopidine in cerebral ischemia.Stroke, , Volume: 20, Issue:12, 1989
Is there a role for leukotrienes as mediators of ethanol-induced gastric mucosal damage?The American journal of physiology, , Volume: 254, Issue:1 Pt 1, 1988
Blood conservation with membrane oxygenators and dipyridamole.The Annals of thoracic surgery, , Volume: 44, Issue:1, 1987
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs.The Journal of surgical research, , Volume: 42, Issue:3, 1987
Renal hemodynamic effects of therapeutic plasma levels of sulindac sulfide during hemorrhage.Kidney international, , Volume: 29, Issue:2, 1986
Maintenance of cerebral circulation during hemorrhagic hypotension in newborn pigs: role of prostanoids.Circulation research, , Volume: 59, Issue:5, 1986
Effect of prostaglandin blockers on ascites fluid in pancreatitis.Surgery, , Volume: 98, Issue:3, 1985
Accumulation of prostacyclin in rat brain during haemorrhagic hypotension--possible role of PGI2 in autoregulation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 4, Issue:1, 1984
Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat. Differentiation of effects between nabumetone and etodolac.Digestive diseases and sciences, , Volume: 39, Issue:3, 1994
Comparison of the effects of nabumetone with indomethacin on rat gastric mucosal 6-keto-PGF1 alpha production and on bile salt-induced changes in gastric mucosal function.The Journal of pharmacy and pharmacology, , Volume: 39, Issue:9, 1987
Gastroprotection by sucralfate against acetylsalicylic acid in humans. Role of endogenous prostaglandins.Scandinavian journal of gastroenterology. Supplement, , Volume: 140, 1987
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[Role of thromboxane A2 and prostacyclin in the pathophysiology of epidemic hemorrhagic fever].Zhonghua yi xue za zhi, , Volume: 70, Issue:7, 1990
Plasma iPGE2 and i6-keto PGF1 alpha in the course of liver cirrhosis.Prostaglandins, , Volume: 53, Issue:1, 1997
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NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines.International journal of cancer, , Jun-10, Volume: 99, Issue:5, 2002
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Equine postanaesthetic myositis: thromboxanes, prostacyclin and prostaglandin E2 production.Veterinary research communications, , Volume: 12, Issue:2-3, 1988
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Eicosanoid production by brain tumours in vivo--evidence for intracranial compartmentation.Journal of neuro-oncology, , Volume: 11, Issue:3, 1991
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A thromboxane A2 synthase inhibitor, DP-1904, prevents rat renal injury.European journal of pharmacology, , Feb-14, Volume: 193, Issue:3, 1991
Prostaglandins in vascular tone in experimental obstructive nephropathy.Kidney international, , Volume: 19, Issue:6, 1981
Thromboxane A2 is the major arachidonic acid metabolite of human cortical hydronephrotic tissue.Prostaglandins, , Volume: 21, Issue:3, 1981
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Comparison of prostaglandin production of skin fibroblasts grown from patients with Bartter's syndrome and from age and sex matched controls.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
Systemic prostaglandin I2 synthesis is normal in patients with Bartter's syndrome.Lancet (London, England), , Aug-13, Volume: 2, Issue:8346, 1983
Prostaglandin excretion in Bartter's syndrome.Klinische Wochenschrift, , Jan-03, Volume: 61, Issue:1, 1983
Urinary excretion rate of 6-keto-prostaglandin F1 alpha as an index of circulating prostacyclin.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
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Nitric oxide reverses endotoxin-induced inflammatory hyperalgesia via inhibition of prostacyclin production in mice.Pharmacological research, , Volume: 53, Issue:2, 2006
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[Studies on prostaglandin production relating to the mechanism of dysmenorrhea in endometriosis].Nihon Naibunpi Gakkai zasshi, , Jan-20, Volume: 70, Issue:1, 1994
Production of hyperalgesic prostaglandins by sympathetic postganglionic neurons.Journal of neurochemistry, , Volume: 53, Issue:5, 1989
[Effect of safflower injection on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 25, Issue:1, 2009
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Dexamethasone pretreatment attenuates cerebral vasodilative responses to hypercapnia and augments vasoconstrictive responses to hyperventilation in newborn pigs.Pediatric research, , Volume: 53, Issue:2, 2003
Endothelial NO and prostanoid involvement in newborn and juvenile pig pial arteriolar vasomotor responses.American journal of physiology. Heart and circulatory physiology, , Volume: 281, Issue:6, 2001
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Transforming growth factor-beta attenuates ischemia-induced alterations in cerebrovascular responses.The American journal of physiology, , Volume: 264, Issue:2 Pt 2, 1993
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Pressure ventilation increases brain vascular prostacyclin production in newborn pigs.Pediatric research, , Volume: 28, Issue:6, 1990
Ischemia alters cerebral vascular responses to hypercapnia and acetylcholine in piglets.Pediatric research, , Volume: 25, Issue:2, 1989
Effects of high frequency oscillatory ventilation compared to conventional ventilation upon pulmonary vascular prostanoid production in neonatal piglets.Prostaglandins, leukotrienes, and medicine, , Volume: 17, Issue:1, 1985
The role of prostacyclin in the hypercapnic and hypoxic cerebrovascular dilations.Life sciences, , May-07, Volume: 34, Issue:19, 1984
Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits.American journal of physiology. Heart and circulatory physiology, , Volume: 297, Issue:5, 2009
Inhibition of 12(S)-hydroxyeicosatetraenoic acid (12-HETE) production suppressed the intimal hyperplasia caused by poor-runoff conditions in the rabbit autologous vein grafts.Journal of cardiovascular pharmacology, , Volume: 36, Issue:5, 2000
Chronic oral defibrotide counteracts hypercholesterolemia noxious effects on cardiovascular function in the rabbit.Thrombosis research, , Jun-01, Volume: 94, Issue:5, 1999
Vitamin E supplementation attenuates myointimal proliferation of the abdominal aorta after balloon injury in diet-induced hypercholesterolemic rabbits.Prostaglandins & other lipid mediators, , Volume: 56, Issue:4, 1998
Fish oil supplementation attenuates myointimal proliferation of the abdominal aorta after balloon injury in diet-induced hypercholesterolemic rabbits.Prostaglandins, , Volume: 49, Issue:5, 1995
Low-dose aspirin does not attenuate platelet aggregation or atherosclerosis in miniature swine but decreases production of aortic wall prostacyclin.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:5, 1995
Prostacyclin, thromboxane A2, and atherosclerosis in young hypercholesterolemic swine.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:4, 1994
Oral cicaprost protects from hypercholesterolaemia-induced impairment of coronary vasodilation.Agents and actions. Supplements, , Volume: 37, 1992
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Eicosapentanoic acid suppresses intimal hyperplasia after expanded polytetrafluoroethylene grafting in rabbits fed a high cholesterol diet.Journal of vascular surgery, , Volume: 13, Issue:4, 1991
The hypertensive response to vasopressor agents stimulates the release of thromboxane A2 in hypercholesterolaemic rabbits.Cardiovascular research, , Volume: 23, Issue:9, 1989
Radioimmunoassay of thromboxane B2 and its preliminary applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:1, 1988
Increased platelet aggregability is associated with increased prostacyclin production by vessel walls in hypercholesterolemic rabbits.Prostaglandins, , Volume: 24, Issue:3, 1982
Effects of the coumarin derivative AD6 on platelet aggregation, platelet vessel wall interactions and 6 keto PGF1 alpha production in perfused aortas, in experimentally hypercholesterolaemic rabbits.Pharmacological research communications, , Volume: 14, Issue:3, 1982
Synthesis of prostaglandins and thromboxane B2 by cholesterol-fed rabbits.Arteriosclerosis and thrombosis : a journal of vascular biology, , Volume: 11, Issue:3
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Effect of extraluminal ATP application on vascular tone and blood flow in skeletal muscle: implications for exercise hyperemia.American journal of physiology. Regulatory, integrative and comparative physiology, , Aug-01, Volume: 305, Issue:3, 2013
[Some mechanisms of the development of endothelial disfunction in aging].Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), , Volume: 50, Issue:2, 2004
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Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators.Physiological research, , Volume: 45, Issue:4, 1996
Role of prostaglandins and histamine in hyperemic response to superficial and deep gastric mucosal injury and H+ back-diffusion in cats.Digestive diseases and sciences, , Volume: 40, Issue:8, 1995
Mechanism of aggravation of mucosal injury by intravenous nicotine in rat stomach.The American journal of physiology, , Volume: 261, Issue:6 Pt 1, 1991
Effect of prostacyclin inhibition by tranylcypromine on uterine 6-keto-pgf 1 alpha levels during estrogen hyperemia in rats.Prostaglandins, , Volume: 23, Issue:5, 1982
Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man.Prostaglandins, leukotrienes, and medicine, , Volume: 9, Issue:4, 1982
Interaction of nicotine and prostaglandins in the cardiovascular system.Prostaglandins, , Volume: 23, Issue:1, 1982
Circulating prostanoid levels, both basal and during the chlorpropamide alcohol flush, in non-insulin dependent diabetes.Clinical endocrinology, , Volume: 15, Issue:5, 1981
Endothelial control of coronary flow in perfused guinea pig heart.Basic research in cardiology, , Volume: 90, Issue:2
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Myocardial reactive hyperaemia in perfused guinea pig heart.Polish journal of pharmacology, , Volume: 47, Issue:5
Modifications in the TXA(2) and PGI(2) plasma levels and some other biochemical parameters during the initiation and development of non-insulin-dependent diabetes mellitus (NIDDM) syndrome in the rabbit.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 62, Issue:5, 2000
Effect of erythrocytes and prostacyclin production in the effect of fructose and sorbitol on platelet activation in human whole blood in vitro.Thrombosis research, , Jun-15, Volume: 86, Issue:6, 1997
Effects of L-arginine infusion on renal hemodynamics and sodium excretion during hypo-, normo-, and hyperinsulinemia, as studied in dogs.American journal of hypertension, , Volume: 9, Issue:7, 1996
Effects of chronic fetal hyperinsulinemia on plasma arachidonic acid and prostaglandin concentrations.American journal of obstetrics and gynecology, , Volume: 161, Issue:4, 1989
Effects of astaxanthin on blood coagulation, fibrinolysis and platelet aggregation in hyperlipidemic rats.Pharmaceutical biology, , Volume: 55, Issue:1, 2017
Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.Chemical & pharmaceutical bulletin, , Volume: 61, Issue:2, 2013
[Relations of platelet phospholipid fatty acids to thrombotic risk factors in middle-aged and geriatric patients with hyperlipidemia].Zhonghua yi xue za zhi, , Jan-09, Volume: 87, Issue:2, 2007
Effects of medicinal cake-separated moxibustion on plasma 6-keto-PGF1alpha and TXB2 contents in the rabbit of hyperlipemia.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 25, Issue:2, 2005
Protective effects of CVPM on vascular endothelium in rats fed cholesterol diet.Clinica chimica acta; international journal of clinical chemistry, , Jul-01, Volume: 333, Issue:1, 2003
Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol.Thrombosis research, , Nov-15, Volume: 100, Issue:4, 2000
Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia?Journal of hypertension, , Volume: 17, Issue:9, 1999
Effect of gemfibrozil on serum levels of prostacyclin and precursor fatty acids in hyperlipidemic patients with Type 2 diabetes.Diabetes research and clinical practice, , Volume: 42, Issue:3, 1998
Influences of dietary omega-3 polyunsaturated fatty acids on the recovery of cardiac and renal functions after preservation in hyperlipidemic rats.Transplantation, , Aug-15, Volume: 64, Issue:3, 1997
[Effects of acupuncture on lipid, TXB2, 6-keto-PGF, alpha in simple obese patients complicated with hyperlipidemia].Zhen ci yan jiu = Acupuncture research, , Volume: 21, Issue:4, 1996
Influence of HDL on the formation of 6-keto-PGF1 alpha and TXB2 in vitro: the importance of the source of HDL.Eicosanoids, , Volume: 5, Issue:1, 1992
[Effect of jiang-zhi zhong-yao-pian on total cholesterol, triglyceride, TXB2, 6-keto-PGF1 alpha in hyperlipemic patients].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:1, 1991
[Effects of corn pollen on the peroxides and 6-keto-PGF1 alpha/TXB2 in hyperlipidemic rabbits].Zhonghua xin xue guan bing za zhi, , Volume: 18, Issue:6, 1990
Effects of purified compound (8501) on hyperlipidemia and the balance between thromboxane A2 and prostacyclin in rabbits.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 5, Issue:4, 1990
[Effects of nifedipine and Paeonia lactiflora on plasma TXB2 and 6-Keto-PGF1 alpha in cholesterol-fed rabbits].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:11, 1990
[Plasma and cellular factors of atherogenesis and the prostanoid system at the early stages of arterial hypertension].Kardiologiia, , Volume: 29, Issue:9, 1989
[Effect of the leech on 6-keto-PGF1 alpha, TXB2, total cholesterol and triglycerides in experimental hyperlipemic rabbits].Zhonghua nei ke za zhi, , Volume: 27, Issue:8, 1988
Increased compliance of niceritrol treatment by addition of aspirin: relationship between changes in prostaglandins and skin flushing.International journal of clinical pharmacology, therapy, and toxicology, , Volume: 25, Issue:12, 1987
[Effect of pollen typhae on 6-keto-PGF1 alpha, TXB2, TC and HDL-C in chronic hyperlipemic rabbits].Zhonghua xin xue guan bing za zhi, , Volume: 14, Issue:5, 1986
Decreased antigen-induced eicosanoid release in conjugated linoleic acid-fed guinea pigs.American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 282, Issue:4, 2002
Rise of prostanoids in rat small intestinal mucosa following intestinal protein hypersensitivity.Pediatric research, , Volume: 21, Issue:4, 1987
Nature of the mast cell-macrophage interaction in immediate hypersensitivity.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 17A, 1987
Thromboxane and prostacyclin release during cardiac immediate hypersensitivity reactions in vitro.The Journal of pharmacology and experimental therapeutics, , Volume: 217, Issue:1, 1981
Potential Biomarkers for the Diagnosis of Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema.ORL; journal for oto-rhino-laryngology and its related specialties, , Volume: 79, Issue:1-2, 2017
Pro Atrial Natriuretic Peptide (1-30) and 6-keto PGF1α Activity Affects Na(+) Homeostasis in Non-modulating Hypertension.Current hypertension reviews, , Volume: 11, Issue:1, 2015
Vasoconstrictor role of cyclooxygenase-1-mediated prostacyclin synthesis in non-insulin-dependent diabetic mice induced by high-fat diet and streptozotocin.American journal of physiology. Heart and circulatory physiology, , Aug-01, Volume: 307, Issue:3, 2014
Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.The Journal of clinical investigation, , Volume: 122, Issue:4, 2012
[Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 10, Issue:9, 2012
Suppression of the nitric oxide pathway in metastatic renal cell carcinoma patients receiving vascular endothelial growth factor-signaling inhibitors.Hypertension (Dallas, Tex. : 1979), , Volume: 56, Issue:6, 2010
Sodium tungstate and vanadyl sulfate effects on blood pressure and vascular prostanoids production in fructose-overloaded rats.Clinical and experimental hypertension (New York, N.Y. : 1993), , Volume: 32, Issue:7, 2010
Diagnostic biomarkers of essential arterial hypertension: the value of prostacyclin, nitric oxide, oxidized-LDL, and peroxide measurements.International heart journal, , Volume: 50, Issue:3, 2009
Gross-total hematoma removal of hypertensive basal ganglia hemorrhages: a long-term follow-up.Journal of the neurological sciences, , Dec-15, Volume: 287, Issue:1-2, 2009
Changes of TXA2 and PGI2 during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, , Volume: 28, Issue:1, 2008
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.Journal of hypertension, , Volume: 26, Issue:12, 2008
Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage.Chinese medical journal, , Dec-05, Volume: 120, Issue:23, 2007
Angiotensin II type 1 receptor antagonism improves endothelial vasodilator function in L-NAME-induced hypertensive rats by a kinin-dependent mechanism.Journal of hypertension, , Volume: 24, Issue:1, 2006
Oral treatment and in vitro incubation with fructose modify vascular prostanoid production in the rat.Autonomic & autacoid pharmacology, , Volume: 26, Issue:1, 2006
Angiotensin-converting enzyme inhibition and angiotensin AT1-receptor antagonism equally improve endothelial vasodilator function in L-NAME-induced hypertensive rats.European journal of pharmacology, , Jun-15, Volume: 516, Issue:3, 2005
Cyclooxygenase inhibition with acetylsalicylic acid unmasks a role for prostacyclin in erythropoietin-induced hypertension in uremic rats.Canadian journal of physiology and pharmacology, , Volume: 83, Issue:6, 2005
Decreased nitric oxide in women with essential hypertension in prehypertensive phase.Croatian medical journal, , Volume: 46, Issue:6, 2005
[Insulin resistance and effects of intravenous acute saline load on renal production of prostaglandin I2 and thromboxane A2 in salt-sensitive hypertensive patients].Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, , Volume: 25, Issue:1, 2005
Prostaglandin I2 does not contribute to the hypotensive effect of the superoxide dismutase mimetic Tempo in rats with aortic coarctation-induced hypertension.Clinical and experimental hypertension (New York, N.Y. : 1993), , Volume: 26, Issue:3, 2004
Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients.Life sciences, , Jan-02, Volume: 74, Issue:7, 2004
Functional study of the [Ca2+]i signaling pathway in aortas of L-NAME-hypertensive rats.Pharmacology, , Volume: 70, Issue:3, 2004
Dietary fish protein lowers blood pressure and alters tissue polyunsaturated fatty acid composition in spontaneously hypertensive rats.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 19, Issue:4, 2003
Increased endothelin: nitric oxide ratio is associated with erythropoietin-induced hypertension in hemodialysis patients.Renal failure, , Volume: 25, Issue:4, 2003
1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats.Peptides, , Volume: 23, Issue:1, 2002
Enalapril and quinapril improve endothelial vasodilator function and aortic eNOS gene expression in L-NAME-treated rats.European journal of pharmacology, , Aug-16, Volume: 450, Issue:1, 2002
Chronic thromboxane synthase inhibition prevents fructose-induced hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 38, Issue:4, 2001
Gender differences in the attenuation of salt-induced hypertension by angiotensin (1-7).Peptides, , Volume: 22, Issue:6, 2001
[Clinical study on conducting physical exercise in lowering blood pressure of hypertensive patients and influencing their endocrine hormones].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 21, Issue:12, 2001
Serotonin hypersensitivity in aorta of two kidney-two clip hypertensive rats: calcium contribution and prostanoids-nitric oxide interactions.Archives of physiology and biochemistry, , Volume: 109, Issue:1, 2001
Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 63, Issue:4, 2000
Different patterns of renal prostaglandins I2 and E2 in patients with essential hypertension with low to normal or high renin activity.Journal of hypertension, , Volume: 18, Issue:8, 2000
Delayed hypotensive effect of the thromboxane A2/prostaglandin H2 receptor antagonist S-1452 in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 27, Issue:8, 2000
Prostacyclin deficiency and reduced fetoplacental blood flow in pregnancy-induced hypertension and preeclampsia.Gynecologic and obstetric investigation, , Volume: 50, Issue:2, 2000
Prostacyclin: its pathogenic role in essential hypertension and the class effect of ACE inhibitors on prostaglandin metabolism.Blood pressure, , Volume: 8, Issue:5-6, 1999
Exercise enhances vasorelaxation in experimental obesity associated hypertension.Cardiovascular research, , Volume: 43, Issue:4, 1999
Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia?Journal of hypertension, , Volume: 17, Issue:9, 1999
Plasma levels of nitric oxide and related vasoactive factors following long-term treatment with angiotensin-converting enzyme inhibitor in patients with essential hypertension.Metabolism: clinical and experimental, , Volume: 48, Issue:10, 1999
Compensatory excretion of prostacyclin and thromboxane metabolites in obstructive sleep apnea syndrome.Internal medicine (Tokyo, Japan), , Volume: 37, Issue:2, 1998
Stimulation of endothelial cell production of vasoconstrictive substances by hypertensive sera.American journal of hypertension, , Volume: 11, Issue:2, 1998
Role of endogenous carbon monoxide in hypertension pathogenesis of rats.Sheng li xue bao : [Acta physiologica Sinica], , Volume: 50, Issue:6, 1998
Vasoactive mediators in pregnancy-induced hypertensive disorders: a longitudinal study.American journal of obstetrics and gynecology, , Volume: 179, Issue:6 Pt 1, 1998
Glomerular thromboxane contributes to pressor response in deoxycorticosterone acetate-salt hypertension.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 58, Issue:2, 1998
Effects of ridogrel, a thromboxane synthase inhibitor and receptor antagonist, on blood pressure in the spontaneously hypertensive rat.Japanese journal of pharmacology, , Volume: 78, Issue:4, 1998
Production of eicosanoids and angiotensin II in resistance vessels in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 25, Issue:6, 1998
Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study.American journal of obstetrics and gynecology, , Volume: 177, Issue:6, 1997
Thromboxane antagonism and cough induced by angiotensin-converting-enzyme inhibitor.Lancet (London, England), , Jul-05, Volume: 350, Issue:9070, 1997
Effects of cicletanine on prostaglandin I2 and E2 levels in patients with essential hypertension.American journal of hypertension, , Volume: 10, Issue:7 Pt 1, 1997
[Influence of qi-gong on plasma TXB2 and 6-keto-PGF1 alpha in two TCM types of essential hypertension].Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, , Volume: 22, Issue:6, 1997
Vasoconstriction of the afferent arteriole and defective renal synthesis of nitric oxide in essential hypertension.Kidney international. Supplement, , Volume: 55, 1996
Prostacyclin biosynthesis in essential hypertension before and during treatment.Journal of human hypertension, , Volume: 10, Issue:1, 1996
Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 80, Issue:1, 1996
Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 54, Issue:3, 1996
[Study on mechanism of eye-signs in blood stasis syndrome].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:4, 1996
[Level of endothelin-1,2,6-keto-pgf1-alpha and atrial natriuretic peptide in serum of pregnant women with late hypertension].Polskie Archiwum Medycyny Wewnetrznej, , Volume: 95, Issue:6, 1996
Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin.The Journal of pharmacology and experimental therapeutics, , Volume: 279, Issue:2, 1996
Amlodipine and haemodynamic effects of cyclo-oxygenase inhibition.British journal of clinical pharmacology, , Volume: 39, Issue:1, 1995
Mesenteric vascular responses to vasopressin during development of DOCA-salt hypertension in male and female rats.The American journal of physiology, , Volume: 268, Issue:1 Pt 2, 1995
[Effect of trapidil in prevention of pre-eclampsia and fetal retardation].Zentralblatt fur Gynakologie, , Volume: 117, Issue:1, 1995
Short-term increase in prostaglandin I2 synthesis caused by cicletanine in patients with essential hypertension.American journal of hypertension, , Volume: 8, Issue:9, 1995
Phorbol ester-stimulated 6-keto-prostaglandin F1 alpha in aortas from control and aldosterone-salt rats.Journal of hypertension, , Volume: 13, Issue:7, 1995
Hypertensive and normal pregnancy: a longitudinal study of blood pressure, distensibility of dorsal hand veins and the ratio of the stable metabolites of thromboxane A2 and prostacyclin in plasma.British journal of obstetrics and gynaecology, , Volume: 102, Issue:11, 1995
Determination of mineral, parathyroid hormone, and 6-keto-prostaglandin-F1 alpha levels in pregnant women with hypertension and pre-eclampsia.Singapore medical journal, , Volume: 36, Issue:6, 1995
Adriamycin-related hypertension in pregnant rats: response to a thromboxane receptor antagonist.Clinical science (London, England : 1979), , Volume: 88, Issue:6, 1995
Plasma and urinary endothelin 1, prostacyclin metabolites and platelet consumption in pre-eclampsia and essential hypertensive pregnancy.Blood pressure, , Volume: 3, Issue:1-2, 1994
Systemic and renal effects of nifedipine in cyclosporine-associated hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 23, Issue:1 Suppl, 1994
[Vasoactive prostanoids and inhibitors of blood coagulation in pregnancy-induced hypertension].Zentralblatt fur Gynakologie, , Volume: 116, Issue:6, 1994
Effect of low-dose treatment with perindopril on cardiac function in stroke-prone spontaneously hypertensive rats: role of bradykinin.Journal of cardiovascular pharmacology, , Volume: 24, Issue:3, 1994
Tacrolimus (FK506)-induced nephrotoxicity in spontaneous hypertensive rats.The Journal of toxicological sciences, , Volume: 19, Issue:4, 1994
The change of penile blood thromboxane B2 and prostacyclin after intracavernous injection of vasoactive drugs for the treatment of arteriogenic impotence.Proceedings of the National Science Council, Republic of China. Part B, Life sciences, , Volume: 18, Issue:1, 1994
[Value of prostaglandins in a pre-eclampsia-equivalent animal model].Zentralblatt fur Gynakologie, , Volume: 116, Issue:5, 1994
Effects of swim training on blood pressure, catecholamines and prostaglandins in spontaneously hypertensive rats.Japanese heart journal, , Volume: 35, Issue:2, 1994
Ridogrel improves maternal/fetal homeostasis in an ovine model of pregnancy-induced hypertension.Prostaglandins, , Volume: 47, Issue:3, 1994
Mechanism for the antihypertensive effect of a polysaccharide-glycopeptide complex from Lactobacillus casei in spontaneously hypertensive rats (SHR).Bioscience, biotechnology, and biochemistry, , Volume: 57, Issue:6, 1993
Hemodynamic and biochemical changes after chronic administration of cilazapril to hypertensive patients.Cardiology, , Volume: 82, Issue:4, 1993
Effect of felodipine-ER on blood pressure, platelet function, and rheological properties in hypertension.The Canadian journal of cardiology, , Volume: 9, Issue:5, 1993
Prostacyclin, thromboxane and antioxidant levels in pregnancy-induced hypertension.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 50, Issue:3, 1993
Correlation between umbilical artery resistance index, 6 ketoprostaglandin F1 alpha and thromboxane B2 in the fetoplacental compartment in patients with pregnancy induced hypertension.Prostaglandins, , Volume: 45, Issue:6, 1993
[The influence of indapamide on 6-keto-PGF1 alpha, PGE2, and PGF2 alpha synthesis and plasma TXB2 levels in spontaneously hypertensive rats].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 15, Issue:1, 1993
The effect of acetaminophen on prostacyclin production in pregnant women.American journal of obstetrics and gynecology, , Volume: 168, Issue:4, 1993
Effects of naftidrofuryl on isolated perfused kidneys of spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 20, Issue:10, 1993
Study of mechanisms of glucocorticoid hypertension in rats: endothelial related changes and their amelioration by dietary fish oils.British journal of pharmacology, , Volume: 106, Issue:2, 1992
[Clinical study of qianxining in the treatment of 60 cases of yang hyperactivity due to yin deficiency type of hypertension].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 12, Issue:7, 1992
Abnormal response of urinary eicosanoid system to norepinephrine infusion in patients with essential hypertension.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 46, Issue:2, 1992
Effects of angiotensin converting enzyme inhibition in adult polycystic kidney disease.Kidney international, , Volume: 41, Issue:1, 1992
3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.Journal of medicinal chemistry, , Feb-21, Volume: 35, Issue:4, 1992
Protective effect of cicletanine on hypertension-induced decreases in the renal kallikrein-kinin and prostaglandin systems in stroke-prone spontaneously hypertensive rats.Journal of cardiovascular pharmacology, , Volume: 20, Issue:4, 1992
Effects of prostacyclin infusion on blood pressure and plasma renin activity in patients with essential hypertension.Angiology, , Volume: 43, Issue:2, 1992
Role of prostanoids in renin-dependent and renin-independent hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 17, Issue:4, 1991
Nifedipine increases urinary excretion of prostacyclin metabolite in hypertensive pregnancy.Pharmacology & toxicology, , Volume: 69, Issue:1, 1991
Arachidonic acid does not share the antihypertensive properties of linoleic acid and fish oil omega-3 fatty acids in a model of angiotensin II-induced hypertension in the rat.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 14, Issue:6, 1991
Renal eicosanoids and renal hemodynamics in early borderline hypertension.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 14, Issue:6, 1991
Effect of aging on endothelin-induced prostaglandin I2 release in isolated hind legs of the spontaneously hypertensive rat.Research communications in chemical pathology and pharmacology, , Volume: 74, Issue:2, 1991
[Experimental study on the treatment of hypertension with combined traditional Chinese and Western medicine].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 11, Issue:11, 1991
[Effect of captopril on urinary 6-keto-PGF1 alpha, thromboxane B2 in inbred SHR rats].Zhonghua xin xue guan bing za zhi, , Volume: 19, Issue:6, 1991
Vascular eicosanoids and platelet-aortic wall interactions in spontaneously hypertensive rats.European journal of pharmacology, , Sep-24, Volume: 202, Issue:3, 1991
Urinary excretion of prostanoids during sleep in obstructive sleep apnoea patients.Clinical and experimental pharmacology & physiology, , Volume: 18, Issue:8, 1991
[Effects of svate on platelet morphology and function in patients with coronary heart disease and hypertension].Zhonghua xin xue guan bing za zhi, , Volume: 19, Issue:3, 1991
Effects of isradipine on platelet function in hypertension at rest and during exercise.American journal of hypertension, , Volume: 4, Issue:2 Pt 2, 1991
Effect of angiotensin-converting enzyme inhibitors on glomerular eicosanoid production in normotensive and spontaneously hypertensive rats.Clinical science (London, England : 1979), , Volume: 81, Issue:4, 1991
The deficit of prostacyclin in the pathogenesis of hypertension.Cor et vasa, , Volume: 33, Issue:6, 1991
Effect of dietary calcium on renal prostaglandins.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 42, Issue:3, 1991
Absence of effects of ketanserin on renal prostacyclin and thromboxane A2 in essential hypertension.European heart journal, , Volume: 12, Issue:4, 1991
Endothelins in perinatal biology.Seminars in perinatology, , Volume: 15, Issue:1, 1991
Changes in vascular wall production of prostacyclin and thromboxane A2 in spontaneously hypertensive rats during maturation and the concomitant development of hypertension.Japanese circulation journal, , Volume: 54, Issue:5, 1990
Effect of furosemide on angiotensin II-mediated prostaglandin I2 production in hypertensive subjects.European journal of clinical pharmacology, , Volume: 39, Issue:2, 1990
Low-dose aspirin. II. Relationship of angiotensin II pressor responses, circulating eicosanoids, and pregnancy outcome.American journal of obstetrics and gynecology, , Volume: 163, Issue:6 Pt 1, 1990
[Prostacyclin and metabolite assay and the clinical significance].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 48 Suppl, 1990
Antithrombotic activity of garlic: its inhibition of the synthesis of thromboxane-B2 during infusion of arachidonic acid and collagen in rabbits.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 41, Issue:2, 1990
[The effect of eicosapentaenoic acid enriched marine oil on the platelet function in hypercoagulable state].Zhonghua nei ke za zhi, , Volume: 29, Issue:7, 1990
Design of an antithrombotic-antihypertensive agent (Wy 27569). Synthesis and evaluation of a series of 2-heteroaryl-substituted dihydropyridines.Journal of medicinal chemistry, , Volume: 33, Issue:2, 1990
Prostanoids and aldosterone-induced mild experimental hypertension in rats.Hypertension (Dallas, Tex. : 1979), , Volume: 15, Issue:2, 1990
Effects of bopindolol on platelet function in hypertension at rest and during exercise.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 40, Issue:2, 1990
Platelet activity, prostacycline metabolite, plasma lipids and sympathoadrenal activity in patients with borderline hypertension and a positive family history of hypertension.Cor et vasa, , Volume: 32, Issue:4, 1990
Effect of sodium restriction on platelet function in patients with essential hypertension.Japanese heart journal, , Volume: 30, Issue:3, 1989
Increased prostaglandin synthesis in the unclipped kidney of one-kidney, one clip hypertensive rats.Journal of hypertension, , Volume: 7, Issue:11, 1989
Prostacyclin synthesis is increased during propranolol therapy for essential hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 19, 1989
Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins.Hypertension (Dallas, Tex. : 1979), , Volume: 14, Issue:4, 1989
[Plasma and cellular factors of atherogenesis and the prostanoid system at the early stages of arterial hypertension].Kardiologiia, , Volume: 29, Issue:9, 1989
Effect of sodium intake on the hypotensive effect of calcium antagonists.Japanese heart journal, , Volume: 30, Issue:6, 1989
The influence of dietary protein on the synthesis of vasoactive substances in subtotally nephrectomized spontaneously hypertensive rats.Japanese heart journal, , Volume: 30, Issue:6, 1989
Role of prostaglandin I2 and thromboxane A2 in the regulation of blood pressure.Nihon Jinzo Gakkai shi, , Volume: 31, Issue:6, 1989
Hostile personality characteristics and prostaglandins in essential hypertension.Psychotherapy and psychosomatics, , Volume: 52, Issue:4, 1989
An increase in the ratio of thromboxane A2 to prostacyclin in association with increased blood pressure in patients on cyclosporine A.Prostaglandins, , Volume: 37, Issue:5, 1989
Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.The New England journal of medicine, , Aug-10, Volume: 321, Issue:6, 1989
Hypertension in bone marrow transplanted patients.Acta clinica Belgica, , Volume: 44, Issue:5, 1989
Prostanoid response in the kidney of hypertensive subjects as part of renal counteraction to gallopamil-induced blood pressure decrease.Acta medica Hungarica, , Volume: 45, Issue:3-4, 1988
Effect of pure eicosapentaenoic acid feeding on blood pressure and vascular reactivity in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 15, Issue:4, 1988
Prostacyclin and thromboxane in pregnancy-induced hypertension.Chinese medical journal, , Volume: 101, Issue:12, 1988
[Basic and clinical studies of angiotensin II pressor responsiveness in pregnancy-induced-hypertension].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 40, Issue:8, 1988
Thromboxane A2 and the development of hypertension in spontaneously hypertensive rats.European journal of pharmacology, , Jan-27, Volume: 146, Issue:1, 1988
Brain eicosanoid levels in spontaneously hypertensive rats after ischemia with reperfusion: leukotriene C4 as a possible cause of cerebral edema.Stroke, , Volume: 19, Issue:3, 1988
Effects of DOCA-salt treatment on the urinary prostaglandins in Sabra rats.Kidney international, , Volume: 33, Issue:5, 1988
Altered excretion of prostaglandin and thromboxane metabolites in pregnancy-induced hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 11, Issue:6 Pt 1, 1988
The effect of dietary fish oil and long-term salt loading on blood pressure and eicosanoid metabolism in spontaneously hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 15, Issue:4, 1988
Effect of potassium supplementation on blood pressure and vasodilator mechanisms in spontaneously hypertensive rats.Clinical science (London, England : 1979), , Volume: 75, Issue:5, 1988
Urinary excretion of 6-keto prostaglandin F1 alpha in pre-eclampsia.Archives of gynecology and obstetrics, , Volume: 244, Issue:1, 1988
Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension.Circulation, , Volume: 75, Issue:5, 1987
Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension.American journal of perinatology, , Volume: 4, Issue:2, 1987
Effects of indomethacin on hormonal and blood pressure responses to captopril in spontaneously hypertensive rats.Pharmacology & toxicology, , Volume: 61, Issue:3, 1987
Dietary suppression of prostaglandin synthesis does not accelerate DOCA/salt hypertension in rats.Clinical and experimental pharmacology & physiology, , Volume: 14, Issue:6, 1987
[Preliminary study on plasma 6-keto-prostaglandin F1 alpha levels before and after induction by furosemide in hypertensive patients].Zhonghua xin xue guan bing za zhi, , Volume: 15, Issue:3, 1987
Beneficial effects of U-63,557A, a thromboxane synthetase inhibitor, in an ovine model of pregnancy-induced hypertension.American journal of obstetrics and gynecology, , Volume: 157, Issue:1, 1987
Potassium supplementation lowers blood pressure in spontaneously hypertensive rats--relationships with urinary prostaglandins and renin.Agents and actions. Supplements, , Volume: 22, 1987
Antihypertensive activity of enalapril. Effect of ibuprofen and different salt intakes.Journal of clinical hypertension, , Volume: 3, Issue:4, 1987
Antihypertensive effect of enalapril in essential hypertension: role of prostacyclin.The American journal of the medical sciences, , Volume: 294, Issue:6, 1987
Prostacyclin in (extracted) plasma of essential hypertensives.Acta cardiologica, , Volume: 42, Issue:2, 1987
[Effect of erect posture on prostacyclin and catecholamines in patients with arterial hypertension].Kardiologia polska, , Volume: 30, Issue:9, 1987
[Measurement of urinary TXB2, 6-keto-PGF1 alpha by radioimmunoassay and its clinical significance].Zhonghua nei ke za zhi, , Volume: 26, Issue:12, 1987
Indomethacin reduces the antihypertensive action of enalapril.Clinical and experimental hypertension. Part A, Theory and practice, , Volume: 9, Issue:2-3, 1987
[Blood lipids, catecholamines, beta-thromboglobulin and prostacyclin in primary arterial hypertension].Kardiologia polska, , Volume: 30, Issue:9, 1987
[Hypertension research in China].Zhonghua xin xue guan bing za zhi, , Volume: 14, Issue:1, 1986
The antihypertensive action of hydrochlorothiazide and renal prostacyclin.Clinical pharmacology and therapeutics, , Volume: 39, Issue:1, 1986
Combination therapy with enalapril and hydrochlorothiazide: optimal dose, renin response, and prostaglandin excretion.Journal of clinical hypertension, , Volume: 2, Issue:1, 1986
Effect of non-steroidal anti-inflammatory drugs on control of hypertension by beta-blockers and diuretics.Lancet (London, England), , May-03, Volume: 1, Issue:8488, 1986
Altered angiotensin-prostanoid interactions in umbilical arteries in pregnancy-induced hypertension.Scandinavian journal of clinical and laboratory investigation. Supplementum, , Volume: 184, 1986
Effects of intravenous administration of a calcium antagonist on prostaglandins and thromboxane in plasma and urine in humans.Prostaglandins, leukotrienes, and medicine, , Volume: 23, Issue:2-3, 1986
Effects of kallidinogenase on urinary kallikrein excretion and plasma prostanoid concentrations in patients with essential hypertension.Experientia, , Sep-15, Volume: 42, Issue:9, 1986
The arthritic patient with hypertension: selection of an NSAID.Scandinavian journal of rheumatology. Supplement, , Volume: 62, 1986
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.Arzneimittel-Forschung, , Volume: 36, Issue:1, 1986
[Plasma thromboxane B2 and 6-keto-prostaglandin F1-alpha concentrations in patients with essential and renovascular hypertension].Zhonghua xin xue guan bing za zhi, , Volume: 14, Issue:1, 1986
Production of prostaglandins I2, E2 and F2 alpha by blood vessels of normotensive and hypertensive, male and female rats.Prostaglandins, leukotrienes, and medicine, , Volume: 25, Issue:2-3, 1986
Different excretion pattern of urinary PGE2 and 6-keto-PGF1 alpha in two kidney-one clip Goldblatt rats.Prostaglandins, leukotrienes, and medicine, , Volume: 24, Issue:1, 1986
[Effect of bilateral common carotid artery ligation on prostaglandin levels (TXA2, PGI2) in spontaneously hypertensive rats (SHRSP, SHRSR) and normotensive rats (WKY)].No to shinkei = Brain and nerve, , Volume: 38, Issue:6, 1986
Arachidonic acid-induced brain ischaemia: different severity between stroke-resistant spontaneously hypertensive rats and Wistar-Kyoto rats.Journal of hypertension. Supplement : official journal of the International Society of Hypertension, , Volume: 4, Issue:3, 1986
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Urinary levels of 2,3-dinor-6-oxo-PGF1 alpha: a reliable index of the production of PGI2 in the spontaneously hypertensive rat.Prostaglandins, , Volume: 29, Issue:4, 1985
Effects of orally administered glandular kallikrein on urinary kallikrein and prostaglandin excretion, plasma immunoreactive prostanoids and platelet aggregation in essential hypertension.Klinische Wochenschrift, , Apr-01, Volume: 63, Issue:7, 1985
Inhibition of prostaglandin synthesis by indomethacin interacts with the antihypertensive effect of atenolol.Clinical pharmacology and therapeutics, , Volume: 38, Issue:4, 1985
Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids.Obstetrics and gynecology, , Volume: 65, Issue:1, 1985
Prostaglandins, renin-angiotensin system, and hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
The effects of nifedipine on platelet aggregation and plasma 6-keto-PGF1 alpha, and its interaction with indomethacin.European journal of clinical pharmacology, , Volume: 29, Issue:4, 1985
[Effect of saralasin on the activity of the renin-angiotensin-aldosterone system, sympathetic-adrenal system and the level of the 6-keto-PGF1 alpha metabolite of prostacyclin in patients with primary arterial hypertension].Kardiologia polska, , Volume: 28, Issue:7, 1985
Urinary 6-keto-PGF1 alpha after captopril and indomethacin: possible contribution of PGI2 to the antihypertensive mechanism of ACE inhibitors.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Dietary fish oil prevents dexamethasone induced hypertension in the rat.Clinical science (London, England : 1979), , Volume: 69, Issue:6, 1985
Renal prostaglandins and hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 13, 1985
Prostacyclin in normal and hypertensive pregnancy.American journal of obstetrics and gynecology, , Nov-15, Volume: 153, Issue:6, 1985
Differing effects of two angiotensin converting enzyme inhibitors, captopril and CI-906, on diuresis and the urinary excretion of kallikrein and prostaglandins in spontaneously hypertensive rats.Scandinavian journal of urology and nephrology. Supplementum, , Volume: 79, 1984
Release of prostaglandins by the mesenteric artery of the renovascular and spontaneously hypertensive rat.Canadian journal of physiology and pharmacology, , Volume: 62, Issue:1, 1984
Urinary 6-ketoprostaglandin F1 alpha in genetically hypertensive rats of the Lyon strain.Clinical science (London, England : 1979), , Volume: 66, Issue:4, 1984
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Evidence that prostacyclin deficiency is a specific feature in preeclampsia.American journal of obstetrics and gynecology, , Mar-15, Volume: 148, Issue:6, 1984
Increased thromboxane A2 production but normal prostacyclin by the placenta in hypertensive pregnancies.Prostaglandins, , Volume: 27, Issue:1, 1984
The role of TXA2 in hypertension.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
Plasma concentrations of 6-keto-prostaglandin F1 alpha, thromboxane B2 and platelet aggregation in patients with essential hypertension.Japanese heart journal, , Volume: 25, Issue:6, 1984
Effects of phospholipases A2 from Vipera russelli snake venom on blood pressure, plasma prostacyclin level and renin activity in rats.Toxicon : official journal of the International Society on Toxinology, , Volume: 22, Issue:2, 1984
The influence of indomethacin and sulindac on some pharmacological actions of atenolol in hypertensive patients.British journal of clinical pharmacology, , Volume: 17 Suppl 1, 1984
PGE2, 6-O-PGF1 alpha and sodium balance in essential hypertensive patients.Prostaglandins, leukotrienes, and medicine, , Volume: 15, Issue:3, 1984
[Effect of psychological stress on the activity of the sympathetic-adrenal system and blood levels of PGE2, PGF2 alpha and 6-keto-PGF1 alpha in patients with primary arterial hypertension].Polskie Archiwum Medycyny Wewnetrznej, , Volume: 72, Issue:4, 1984
Plasma prostaglandins during the intravenous infusion of angiotensin II in pregnant women.American journal of obstetrics and gynecology, , Dec-15, Volume: 150, Issue:8, 1984
Responses of urinary 6-keto-prostaglandin F1 alpha to furosemide administration test in patients with essential hypertension.Nihon Jinzo Gakkai shi, , Volume: 26, Issue:9, 1984
Plasma levels of 6-keto-prostaglandin F1 alpha in normotensive subjects and patients with essential hypertension.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:4, 1983
Plasma levels of 6-keto-prostaglandin F1 alpha in normotensive subjects and patients with essential hypertension.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
Renin-angiotensin system and prostacyclin biosynthesis in streptozotocin diabetic rats.European journal of pharmacology, , Oct-14, Volume: 94, Issue:1-2, 1983
Levels of plasma 6-keto-PGF1 alpha in normotensive and essential hypertensive males with and without a family history of hypertension.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:1, 1983
Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:2, 1983
Responses to furosemide in normotensive and hypertensive subjects.Clinical pharmacology and therapeutics, , Volume: 34, Issue:5, 1983
Effect of aging on 6-keto-PGF1 alpha levels in normotensive and essential hypertensive males.Japanese circulation journal, , Volume: 47, Issue:3, 1983
Imbalanced prostacyclin and thromboxane A2 production in essential hypertension.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
Leukotriene D4: divergent cardiovascular and sympathetic effects in spontaneously hypertensive and normotensive Wistar-Kyoto rats.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 11, 1983
[Levels of plasma 6-keto-PGF1 alpha in normotensive and essential hypertensive males with and without a family history of hypertension and effects of aging].Nihon Naibunpi Gakkai zasshi, , Oct-20, Volume: 58, Issue:10, 1982
Attenuation of the development of hypertension in spontaneously hypertensive rats by the thromboxane synthetase inhibitor, 4'-(imidazol-1-yl) acetophenone.Prostaglandins, , Volume: 24, Issue:2, 1982
Leukotriene D4: cardiovascular and sympathetic effects in spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats.The Journal of pharmacology and experimental therapeutics, , Volume: 223, Issue:1, 1982
Plasma prostanoids in pregnancy-induced hypertension.British journal of obstetrics and gynaecology, , Volume: 89, Issue:8, 1982
Effects of norepinephrine infusion on systemic hemodynamics and plasma 6-keto-prostaglandin F1 alpha in normotensive subjects and patients with essential hypertension.Japanese circulation journal, , Volume: 46, Issue:5, 1982
Angiotensin-converting enzyme inhibition and prostaglandins.The American journal of cardiology, , Apr-21, Volume: 49, Issue:6, 1982
Factors affecting the production of prostacyclin in man.Progress in lipid research, , Volume: 20, 1981
Decrease prostacyclin production: a characteristic of chronic placental insufficiency syndromes.Lancet (London, England), , May-23, Volume: 1, Issue:8230, 1981
In vivo production of prostaglandin I2 in Dahl salt-sensitive and salt-resistant rats.Hypertension (Dallas, Tex. : 1979), , Volume: 5, Issue:5
[Intracellular electrolytes and selected biochemical parameters in patients with borderline arterial hypertension and positive family history of hypertension].Polski tygodnik lekarski (Warsaw, Poland : 1960), , Volume: 44, Issue:30-31
Defective synthesis of vasodilator prostaglandins in the spontaneously hypertensive rat.Hypertension (Dallas, Tex. : 1979), , Volume: 6, Issue:2 Pt 2
Altered aortic production of 6-keto-prostaglandin F1 alpha from aldosterone-salt hypertensive rats.Journal of vascular research, , Volume: 29, Issue:3
Inhibition by aspirin of the stimulated PGI2 synthesis after administration of kallikrein to hypertensive patients (new aspects of chemical pathogeny concerning the messenger systems: A and C).Endocrinologie, , Volume: 25, Issue:2
The effect of Enalapril on PGI(2) and NO levels in hypertensive patients.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 66, Issue:5-6
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.World journal of gastroenterology, , Oct-14, Volume: 13, Issue:38, 2007
[The effect of PGI2 on formation and development of hyperdynamic circulatory state in portal hypertensive rats].Zhonghua wai ke za zhi [Chinese journal of surgery], , Volume: 41, Issue:7, 2003
Endothelial COX-1 and -2 differentially affect reactivity of MVB in portal hypertensive rats.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 283, Issue:3, 2002
Adaptive vasodilatory response after octreotide treatment.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 281, Issue:1, 2001
[Effects of sandostatin on gastric mucosal perfusion in rats with portal hypertensive gastropathy].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, , Volume: 8, Issue:1, 2000
Effects of nitric oxide inhibitor on prostacyclin biosynthesis in portal hypertensive rats.Chinese medical journal, , Volume: 112, Issue:6, 1999
A selective cyclo-oxygenase-2 inhibitor, NS-398, may improve portal hypertension without inducing gastric mucosal injury.Journal of gastroenterology and hepatology, , Volume: 14, Issue:7, 1999
Mechanism of overproduction of plasma prostacyclin in portal hypertensive rats.Chinese medical journal, , Volume: 111, Issue:12, 1998
Increased prostacyclin content in gastric mucosa of cirrhotic patients with portal hypertensive gastropathy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:1, 1995
Role of prostacyclin in hemodynamic alterations in conscious rats with extrahepatic or intrahepatic portal hypertension.Hepatology (Baltimore, Md.), , Volume: 18, Issue:3, 1993
Systemic prostacyclin in cirrhotic patients. Relationship with portal hypertension and changes after intestinal decontamination.Gastroenterology, , Volume: 102, Issue:1, 1992
Biosynthesis of TXB2 and 6-oxo-PGF1 alpha in the heart and other tissues under pathophysiological conditions.Agents and actions. Supplements, , Volume: 37, 1992
Evidence for role of prostacyclin as a systemic hormone in portal hypertension.Surgery, , Volume: 109, Issue:2, 1991
Impaired generation of prostaglandins from isolated gastric surface epithelial cells in portal hypertensive rats.Prostaglandins, , Volume: 40, Issue:4, 1990
[Pulmonary vascular changes after portasystemic shunt operation in rats].Nihon Geka Gakkai zasshi, , Volume: 90, Issue:6, 1989
Prostacyclin in the circulation of patients with vascular disorders undergoing surgery.Clinical science (London, England : 1979), , Volume: 71, Issue:6, 1986
Lack of effect of indomethacin on systemic and splanchnic haemodynamics in portal hypertensive rats.Clinical science (London, England : 1979), , Volume: 68, Issue:5, 1985
The effect of prostacyclin on the gastric mucosa in portal-hypertensive rats.Hepato-gastroenterology, , Volume: 49, Issue:43
In search of pulmonary hypertension treatments: Effect of 17β-estradiol on PGIProstaglandins, leukotrienes, and essential fatty acids, , Volume: 172, 2021
Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats.Respiratory research, , 08-04, Volume: 17, Issue:1, 2016
Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension.Respiratory research, , 08-31, Volume: 17, Issue:1, 2016
Hepatocyte growth factor improves the survival of rats with pulmonary arterial hypertension via the amelioration of pulmonary hemodynamics.International journal of molecular medicine, , Volume: 27, Issue:4, 2011
Mesenchymal stem cell-based prostacyclin synthase gene therapy for pulmonary hypertension rats.Basic research in cardiology, , Volume: 105, Issue:3, 2010
Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin.American journal of medical genetics. Part A, , Volume: 152A, Issue:8, 2010
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AAV-PGIS gene transfer improves hypoxia-induced pulmonary hypertension in mice.Biochemical and biophysical research communications, , Nov-23, Volume: 363, Issue:3, 2007
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats.Hypertension (Dallas, Tex. : 1979), , Volume: 50, Issue:3, 2007
[Prostacyclin and their metabolites].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 63 Suppl 8, 2005
Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats.Human gene therapy, , Volume: 15, Issue:12, 2004
Arachidonic acid metabolites and an early stage of pulmonary hypertension in chronically hypoxic newborn pigs.American journal of physiology. Lung cellular and molecular physiology, , Volume: 284, Issue:2, 2003
[Effect of aspirin on pulmonary hypertension in rat during chronic hypoxia and hypercapnia].Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, , Volume: 19, Issue:4, 2003
Exaggerated hypoxic pulmonary hypertension in endothelin B receptor-deficient rats.American journal of physiology. Lung cellular and molecular physiology, , Volume: 282, Issue:4, 2002
Increased pulmonary prostacyclin synthesis in rats with chronic hypoxic pulmonary hypertension.Cardiovascular research, , Volume: 55, Issue:1, 2002
Determination of prostacyclin in plasma through a bioluminescent immunoassay for 6-keto-prostaglandin F1alpha: implication of dosage in patients with primary pulmonary hypertension.Analytical chemistry, , Aug-01, Volume: 74, Issue:15, 2002
Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock.Critical care medicine, , Volume: 29, Issue:7, 2001
Effects of milrinone on platelet aggregation in swine with pulmonary hypertension.Journal of critical care, , Volume: 15, Issue:3, 2000
[Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension].Terapevticheskii arkhiv, , Volume: 72, Issue:4, 2000
Gene transfer of human prostacyclin synthase ameliorates monocrotaline-induced pulmonary hypertension in rats.Circulation, , Oct-17, Volume: 102, Issue:16, 2000
Interferon-alpha elevates pulmonary blood pressure in sheep--the role of thromboxane cascade.European journal of pharmacology, , Apr-09, Volume: 370, Issue:2, 1999
Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats.Anesthesia and analgesia, , Volume: 89, Issue:4, 1999
[Effects in tetramethylpyrazine on TXA2 and PGI2 by cardio-pulmonary bypass in congenital heart diseases with pulmonary hypertension patients].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 18, Issue:6, 1998
Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs.Critical care medicine, , Volume: 25, Issue:7, 1997
[Short- and long-term effects of the new oral prostacyclin analogue, beraprost sodium, in patients with severe pulmonary hypertension].Journal of cardiology, , Volume: 27, Issue:4, 1996
Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 80, Issue:1, 1996
Delayed thromboxane or tumor necrosis factor-alpha, but not leukotriene inhibition, attenuates prolonged pulmonary hypertension in endotoxemia.The American journal of the medical sciences, , Volume: 310, Issue:3, 1995
Effects of ONO-5046, a specific neutrophil elastase inhibitor, on endotoxin-induced lung injury in sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 77, Issue:3, 1994
Some humoral factors and their interaction on acute hypoxic pulmonary pressor response.Chinese medical journal, , Volume: 107, Issue:2, 1994
Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:1, 1993
Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease.Circulation, , Volume: 88, Issue:5 Pt 1, 1993
Effects of recombinant human superoxide dismutase on tumor necrosis factor-induced lung injury in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:6, 1993
Effects of continuous infusion of nitroglycerin on pulmonary hemodynamics, lung lymph balance, and prostanoid products in the response to endotoxin in awake sheep.Lung, , Volume: 171, Issue:1, 1993
Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continuous infusion of platelet-activating factor.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:2, 1993
Capsular type-specific polysaccharide partially inhibits group B Streptococcus-induced pulmonary hypertension.The American review of respiratory disease, , Volume: 148, Issue:1, 1993
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.The New England journal of medicine, , Jul-09, Volume: 327, Issue:2, 1992
Effect of endotoxin on hypoxic pulmonary vasoconstriction--the role of prostaglandins and leukotrienes.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 12, Issue:1, 1992
Thromboxane and prostacyclin metabolites in pulmonary hypertension.The New England journal of medicine, , Nov-12, Volume: 327, Issue:20, 1992
Plasma prostanoids in neonates with pulmonary hypertension treated with conventional therapy and with extracorporeal membrane oxygenation.The Journal of thoracic and cardiovascular surgery, , Volume: 101, Issue:6, 1991
Effects of hyperventilation on prostacyclin formation and on pulmonary vasodilation after group B beta-hemolytic streptococci-induced pulmonary hypertension.Pediatric research, , Volume: 29, Issue:3, 1991
Vascular resistance and Kf in normal and PMA-injured rabbit lungs: effects of adenosine.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 71, Issue:2, 1991
Prostanoid production and pulmonary hypertension after fat embolism are not modified by methylprednisolone.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 38, Issue:5, 1991
Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs.The American review of respiratory disease, , Volume: 143, Issue:4 Pt 1, 1991
[Changes of thromboxane A2 (TXA2) and prostacyclin (PGI2) in COPD patients with pulmonary hypertension].Zhonghua nei ke za zhi, , Volume: 30, Issue:2, 1991
[Effect of products released by activated neutrophils on pulmonary arterial pressure].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 13, Issue:5, 1990
The prominent role of thromboxane A2 formation on early pulmonary hypertension induced by oleic acid administration in sheep.Thrombosis research, , Apr-01, Volume: 58, Issue:1, 1990
Pulmonary hypertensive response to foreign body microemboli.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:2, 1990
Lipoxygenase and cyclooxygenase blockade by BW755C does not prevent the secondary phase of septic pulmonary hypertension.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 37, Issue:2, 1989
[Pulmonary vascular changes after portasystemic shunt operation in rats].Nihon Geka Gakkai zasshi, , Volume: 90, Issue:6, 1989
Endogenous formation of prostanoids in neonates with persistent pulmonary hypertension.Archives of disease in childhood, , Volume: 64, Issue:7 Spec No, 1989
[Preliminary observation on plasma level of 5-HT, TXB2 and 6-keto-PGF1 alpha in TEPH].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 10, Issue:5, 1988
6-Ketoprostaglandin F1 alpha and thromboxane B2 in isolated, blood-perfused lungs from monocrotaline pyrrole-treated rats.Journal of toxicology and environmental health, , Volume: 23, Issue:1, 1988
Eicosanoids are involved in the permeability changes but not the pulmonary hypertension after systemic activation of complement.Laboratory investigation; a journal of technical methods and pathology, , Volume: 58, Issue:3, 1988
Effects of CGS-13080, a thromboxane inhibitor, on pulmonary vascular resistance in patients after mitral valve replacement surgery.Circulation, , Volume: 78, Issue:3 Pt 2, 1988
Selective inhibition of thromboxane synthetase reduces group-B-beta-hemolytic-streptococci-induced pulmonary hypertension in piglets.Developmental pharmacology and therapeutics, , Volume: 11, Issue:5, 1988
Rat pulmonary artery restructuring and pulmonary hypertension induced by continuous Escherichia coli endotoxin infusion.Laboratory investigation; a journal of technical methods and pathology, , Volume: 56, Issue:2, 1987
6-keto prostaglandin F1 alpha and thromboxane B2 in isolated, buffer-perfused lungs from monocrotaline pyrrole-treated rats.Experimental lung research, , Volume: 12, Issue:3, 1987
Absence of prostaglandin changes associated with protamine administration in patients with pulmonary hypertension.Journal of cardiothoracic anesthesia, , Volume: 1, Issue:5, 1987
Direct and indirect effects of leukotriene D4 on the lungs of unanesthetized sheep.Respiration; international review of thoracic diseases, , Volume: 51, Issue:4, 1987
Leukotriene antagonist FPL 57231 prevents the acute pulmonary effects of Escherichia coli endotoxin in cats.Circulatory shock, , Volume: 21, Issue:2, 1987
Prostanoids in neonates with persistent pulmonary hypertension.The Journal of pediatrics, , Volume: 110, Issue:3, 1987
Effects of a thromboxane antagonist (BM 13.177) during endotoxin-induced pulmonary vasoconstriction in sheep.Clinical physiology (Oxford, England), , Volume: 6, Issue:5, 1986
Low-dose PGI2 prevents monocrotaline-induced thromboxane production and lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:2, 1986
Diethylcarbamazine on pulmonary vascular response to endotoxin in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:4, 1986
Effects of verapamil on thromboxane synthesis and pulmonary hypertension in sheep.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 9, Issue:3, 1986
Thromboxane as a mediator of pulmonary dysfunction during intravascular complement activation in sheep.The American review of respiratory disease, , Volume: 133, Issue:2, 1986
Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep.The American review of respiratory disease, , Volume: 132, Issue:3, 1985
Effects of imidazole and indomethacin on fluid balance in isolated sheep lungs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 58, Issue:3, 1985
Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.The American journal of physiology, , Volume: 248, Issue:6 Pt 2, 1985
Pulmonary dysfunction secondary to soft-tissue endotoxin.Archives of surgery (Chicago, Ill. : 1960), , Volume: 120, Issue:2, 1985
Arachidonic acid metabolites as mediators of lung injury during intravascular complement activation.Progress in biochemical pharmacology, , Volume: 20, 1985
Extracorporeal membrane oxygenation and congenital diaphragmatic hernia: modification of the pulmonary vasoactive profile.Journal of pediatric surgery, , Volume: 20, Issue:6, 1985
Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep.Circulation research, , Volume: 52, Issue:1, 1983
Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581.The Journal of pharmacology and experimental therapeutics, , Volume: 222, Issue:2, 1982
Thromboxane and pulmonary hypertension following E. coli endotoxin infusion in sheep: effect of an imidazole derivative.Prostaglandins, , Volume: 23, Issue:3, 1982
Thromboxane mediates acute pulmonary hypertension in sheep extracorporeal perfusion.The American journal of physiology, , Volume: 243, Issue:3, 1982
Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.Canadian journal of physiology and pharmacology, , Volume: 93, Issue:4, 2015
N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, , Volume: 58, Issue:3, 2007
TP receptors regulate renal hemodynamics during angiotensin II slow pressor response.American journal of physiology. Renal physiology, , Volume: 287, Issue:4, 2004
Early endothelial dysfunction following renal mass reduction in rats.European journal of clinical investigation, , Volume: 33, Issue:1, 2003
Effects of cicletanine on the progression of renal failure in 5/6 nephrectomized hypertensive rats.Clinical and experimental pharmacology & physiology, , Volume: 26, Issue:3, 1999
Effects of OKY-046, a selective thromboxane synthetase inhibitor, on blood pressure and thromboxane synthesis in spontaneously hypertensive rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 37, Issue:3, 1989
Renal vein prostaglandins in renovascular hypertensive patients.Prostaglandins, leukotrienes, and medicine, , Volume: 19, Issue:3, 1985
The effect of dietary alteration of prostaglandin synthesis on blood pressure and the reversal of hypertension in the one-kidney, one-clip rat.Prostaglandins, , Volume: 29, Issue:5, 1985
Effects of renal denervation of the contralateral kidney on blood pressure and sodium and eicosanoid excretion in the chronic phase of two-kidney, one-clip renovascular hypertension in rats.Scandinavian journal of urology and nephrology, , Volume: 39, Issue:1, 2005
[Effect of xueling on relating substances of renal hypertension in rats].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 23, Issue:6, 1998
The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats.The American journal of physiology, , Volume: 257, Issue:2 Pt 2, 1989
Glomerular prostaglandin production in diabetic rats with renovascular hypertension.Kidney international, , Volume: 33, Issue:6, 1988
Dexamethasone attenuates reversal of hypertension in one-kidney, one-clip rats.The American journal of physiology, , Volume: 255, Issue:4 Pt 2, 1988
Vasodepressor phospholipids in reversal of renal hypertension.Agents and actions. Supplements, , Volume: 22, 1987
Increased aortic PGI2 and plasma lyso-PAF in the unclipped one-kidney hypertensive rat.The American journal of physiology, , Volume: 251, Issue:6 Pt 2, 1986
[Plasma thromboxane B2 and 6-keto-prostaglandin F1-alpha concentrations in patients with essential and renovascular hypertension].Zhonghua xin xue guan bing za zhi, , Volume: 14, Issue:1, 1986
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.Arzneimittel-Forschung, , Volume: 36, Issue:1, 1986
Renal prostanoids after unclipping the denervated one-kidney, one-clip hypertensive rat.The American journal of physiology, , Volume: 249, Issue:4 Pt 2, 1985
Dissociation of effects of dietary fatty acids on blood pressure and prostanoid metabolism in Goldblatt hypertensive rats.Journal of hypertension, , Volume: 2, Issue:1, 1984
Urinary 6-keto PGF1 alpha and PGE2 in two kidney-one clip hypertension in the rat.Prostaglandins, leukotrienes, and medicine, , Volume: 13, Issue:3, 1984
Dietary modification of platelet and renal prostaglandins.Australian and New Zealand journal of medicine, , Volume: 14, Issue:4, 1984
Release of prostaglandins by the mesenteric artery of the renovascular and spontaneously hypertensive rat.Canadian journal of physiology and pharmacology, , Volume: 62, Issue:1, 1984
Changes in prostanoid synthesis in response to diet and hypertension in one-kidney, one clip rats.Hypertension (Dallas, Tex. : 1979), , Volume: 7, Issue:6 Pt 1
Dexamethasone pretreatment attenuates cerebral vasodilative responses to hypercapnia and augments vasoconstrictive responses to hyperventilation in newborn pigs.Pediatric research, , Volume: 53, Issue:2, 2003
Effects of hyperventilation on prostacyclin formation and on pulmonary vasodilation after group B beta-hemolytic streptococci-induced pulmonary hypertension.Pediatric research, , Volume: 29, Issue:3, 1991
Hyperventilation stimulates the release of prostaglandin I2 and E2 from lung in humans.Prostaglandins, , Volume: 39, Issue:6, 1990
Hyperventilation, alkalosis, prostaglandins, and pulmonary circulation of the newborn.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 61, Issue:6, 1986
Is hyperventilation a physiologically significant stimulus for prostaglandin release in the human pulmonary vascular bed?Prostaglandins, leukotrienes, and medicine, , Volume: 19, Issue:2, 1985
Respiratory movements alter the generation of prostacyclin and thromboxane A2 in isolated rat lungs: the influence of arachidonic acid-pathway inhibitors on the ratio between pulmonary prostacyclin and thromboxane A2.Prostaglandins, , Volume: 21, Issue:3, 1981
Induction of microsomal prostaglandin E2 synthase in the macula densa in children with hypokalemic salt-losing tubulopathies.Pediatric research, , Volume: 55, Issue:2, 2004
Interactions between the renin-angiotensin system and prostanoids in modulating renal function in potassium-depleted healthy women.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 50, Issue:6, 1994
Hypokalaemia stimulates prostacyclin synthesis in the rat.Clinical science (London, England : 1979), , Volume: 65, Issue:1, 1983
Plasma 6-keto-prostaglandin F1 alpha in disorders involving hypokalemia.Prostaglandins, leukotrienes, and medicine, , Volume: 9, Issue:5, 1982
Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats.European journal of pharmacology, , May-05, Volume: 802, 2017
Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial.BMC surgery, , Aug-11, Volume: 17, Issue:1, 2017
Flurbiprofen axetil provides a prophylactic benefit against mesenteric traction syndrome associated with remifentanil infusion during laparotomy.Journal of anesthesia, , Volume: 26, Issue:4, 2012
Remifentanil increases the incidence of mesenteric traction syndrome: preliminary randomized controlled trial.Journal of anesthesia, , Volume: 24, Issue:5, 2010
Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1.European journal of pharmacology, , May-01, Volume: 536, Issue:3, 2006
Role of sensory neuron in reduction of endotoxin-induced hypotension in rats.Critical care medicine, , Volume: 33, Issue:4, 2005
Influences of prostanoids and nitric oxide on post-suspension hypotension in female Sprague-Dawley rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 68, Issue:3, 2003
Baroreceptor and prostanoid control of fetal renal cortical blood flow and plasma renin activity.Reproduction, fertility, and development, , Volume: 13, Issue:2-3, 2001
Effects of inhibitors of the activity of cyclo-oxygenase-2 on the hypotension and multiple organ dysfunction caused by endotoxin: a comparison with dexamethasone.British journal of pharmacology, , Volume: 124, Issue:3, 1998
Haemodynamic and haematologic effects of Acanthaster planci venom in dogs.Toxicon : official journal of the International Society on Toxinology, , Volume: 32, Issue:10, 1994
Superoxide scavengers do not prevent ischemia-induced alteration of cerebral vasodilation in piglets.Pediatric research, , Volume: 33, Issue:2, 1993
Transforming growth factor-beta attenuates ischemia-induced alterations in cerebrovascular responses.The American journal of physiology, , Volume: 264, Issue:2 Pt 2, 1993
Contribution of prostacyclin to D-tubocurarine-induced hypotension in humans.Anesthesiology, , Volume: 72, Issue:1, 1990
The role of prostacyclin in the mesenteric traction syndrome during anesthesia for abdominal aortic reconstructive surgery.Annals of surgery, , Volume: 209, Issue:3, 1989
Prostanoids and pial arteriolar diameter in hypotensive newborn pigs.The American journal of physiology, , Volume: 252, Issue:4 Pt 2, 1987
Maintenance of cerebral circulation during hemorrhagic hypotension in newborn pigs: role of prostanoids.Circulation research, , Volume: 59, Issue:5, 1986
Prostacyclin biosynthesis and hypotension in relation to complement activation in rabbit endotoxic shock.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
Accumulation of prostacyclin in rat brain during haemorrhagic hypotension--possible role of PGI2 in autoregulation.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, , Volume: 4, Issue:1, 1984
Urinary 6-ketoprostaglandin F1 alpha in genetically hypertensive rats of the Lyon strain.Clinical science (London, England : 1979), , Volume: 66, Issue:4, 1984
The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs.Thrombosis research, , Apr-01, Volume: 30, Issue:1, 1983
Contribution of complement activation to the rise in blood levels of 6-oxo-prostaglandin F1 alpha during endotoxin-induced hypotension in rabbits.European journal of pharmacology, , Apr-08, Volume: 79, Issue:1-2, 1982
Complement activation and blood levels of 6-oxo-prostaglandin F1alpha during endotoxin-induced hypotension in rabbits.Archives internationales de pharmacodynamie et de therapie, , Volume: 249, Issue:2, 1981
Release of PGE and PGI2 in the pump-perfused dog kidney and associated hypotension.The American journal of physiology, , Volume: 240, Issue:6, 1981
Blood levels of 6-oxo-prostaglandin F 1 alpha during endotoxin-induced hypotension in rabbits.European journal of pharmacology, , Apr-11, Volume: 63, Issue:1, 1980
Endotoxin-induced hypotension and blood levels of 6-keto-prostaglandin F1 alpha.Advances in prostaglandin and thromboxane research, , Volume: 7, 1980
The change of penile blood thromboxane B2 and prostacyclin after intracavernous injection of vasoactive drugs for the treatment of arteriogenic impotence.Proceedings of the National Science Council, Republic of China. Part B, Life sciences, , Volume: 18, Issue:1, 1994
The change of urinary 11-dehydro-thromboxane B2 and 2,3-dinor-6-keto-prostaglandin F1 alpha in arteriogenic impotence.The Journal of urology, , Volume: 148, Issue:2 Pt 1, 1992
Thromboxane B2 production during erection.Andrologia, , Volume: 18, Issue:2
Eicosanoid levels in CSF of premature infants with posthemorrhagic hydrocephalus.The American journal of the medical sciences, , Volume: 299, Issue:4, 1990
Decreased lipid intake reduces morbidity in sick premature neonates.The Journal of pediatrics, , Volume: 113, Issue:6, 1988
Elevated levels of immunoreactive prostacyclin metabolite in babies who develop intraventricular haemorrhage.Acta paediatrica Scandinavica, , Volume: 76, Issue:1, 1987
Prostaglandins and echocardiography in the assessment of patent ductus arteriosus.Critical care medicine, , Volume: 14, Issue:5, 1986
Systemic production of prostacyclin and thromboxane A2 does not correlate with patency of the ductus arteriosus in very low birth weight infants.The Journal of pediatrics, , Volume: 108, Issue:6, 1986
Early administration of indomethacin to preterm infants.Archives of disease in childhood, , Volume: 61, Issue:3, 1986
Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants.The Journal of pediatrics, , Volume: 107, Issue:6, 1985
Diuresis and respiratory distress syndrome: physiologic mechanisms and therapeutic implications.The Journal of pediatrics, , Volume: 102, Issue:6, 1983
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Intravenous aspirin at reperfusion does not reduce infarct size in the dog with a residual critical stenosis.Journal of cardiovascular pharmacology, , Volume: 34, Issue:4, 1999
Intrauterine infection and the effects of inflammatory mediators on prostaglandin production by myometrial cells from pregnant women.American journal of obstetrics and gynecology, , Volume: 174, Issue:2, 1996
Non-invasive assessment of the cardiovascular eicosanoids, thromboxane A2 and prostacyclin, in randomly sampled males, with special reference to the influence of inheritance and environmental factors.Clinical science (London, England : 1979), , Volume: 79, Issue:6, 1990
Time course of trauma induced alterations of plasma prostanoid levels in intensive care patients.Progress in clinical and biological research, , Volume: 301, 1989
Abnormal uterus with polycysts, accumulation of uterine prostaglandins, and reduced fertility in mice heterozygous for acyl-CoA synthetase 4 deficiency.Biochemical and biophysical research communications, , Jun-22, Volume: 284, Issue:4, 2001
Retention of intrauterine fetal bone increases menstrual prostaglandins.Obstetrics and gynecology, , Volume: 75, Issue:3 Pt 2, 1990
Peritoneal fluid volume, estrogen, progesterone, prostaglandin, and epidermal growth factor concentrations in patients with and without endometriosis.Obstetrics and gynecology, , Volume: 68, Issue:2, 1986
Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay.American journal of obstetrics and gynecology, , Volume: 154, Issue:6, 1986
[Prostanoids of the peritoneal fluid and sterility with or without pelvic lesions (endometriosis, postinfectious adhesions)].Pathologie-biologie, , Volume: 34, Issue:2, 1986
Peritoneal fluid 6-keto prostaglandin F1 alpha levels in women with endometriosis.American journal of obstetrics and gynecology, , Aug-01, Volume: 152, Issue:7 Pt 1, 1985
Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis.American journal of obstetrics and gynecology, , Jun-15, Volume: 140, Issue:4, 1981
Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats.European journal of pharmacology, , May-05, Volume: 802, 2017
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.Journal of pharmacological sciences, , Volume: 130, Issue:2, 2016
Decrease in inflammatory response does not prevent placental dysfunction after fetal cardiac bypass in goats.The Journal of thoracic and cardiovascular surgery, , Volume: 143, Issue:2, 2012
Selective cyclooxygenase-2 inhibition directly increases human vascular reactivity to norepinephrine during acute inflammation.Cardiovascular research, , Feb-01, Volume: 81, Issue:2, 2009
Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells.Circulation research, , Feb-27, Volume: 104, Issue:4, 2009
Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor.British journal of pharmacology, , Volume: 156, Issue:5, 2009
PPAR activators and COX inhibitors selectively block cytokine-induced COX-2 expression and activity in human aortic smooth muscle cells.European journal of pharmacology, , Mar-15, Volume: 606, Issue:1-3, 2009
Increased responsiveness of human coronary artery endothelial cells in inflammation and coagulation.Mediators of inflammation, , Volume: 2009, 2009
Lysophosphatidylcholine induces inflammatory activation of human coronary artery smooth muscle cells.Molecular and cellular biochemistry, , Volume: 295, Issue:1-2, 2007
Dietary supplementation with trans-11- and trans-12-18 : 1 increases cis-9, trans-11-conjugated linoleic acid in human immune cells, but without effects on biomarkers of immune function and inflammation.The British journal of nutrition, , Volume: 97, Issue:6, 2007
Nitric oxide reverses endotoxin-induced inflammatory hyperalgesia via inhibition of prostacyclin production in mice.Pharmacological research, , Volume: 53, Issue:2, 2006
Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats.Critical care medicine, , Volume: 34, Issue:7, 2006
Antithrombin reduces the ischemia/reperfusion-induced spinal cord injury in rats by attenuating inflammatory responses.Thrombosis and haemostasis, , Volume: 91, Issue:1, 2004
Decreased lung tumorigenesis in mice genetically deficient in cytosolic phospholipase A2.Carcinogenesis, , Volume: 25, Issue:8, 2004
Contribution of interaction between nitric oxide and cyclooxygenases to the production of prostaglandins in carrageenan-induced inflammation.Anesthesiology, , Volume: 101, Issue:4, 2004
Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis.Arthritis research & therapy, , Volume: 6, Issue:4, 2004
Role of human heme oxygenase-1 in attenuating TNF-alpha-mediated inflammation injury in endothelial cells.Journal of cellular biochemistry, , Volume: 87, Issue:4, 2002
Inflammatory response during abdominal and thyroid surgery: a prospective clinical trial on mediator release.Shock (Augusta, Ga.), , Volume: 16, Issue:5, 2001
The role of prostanoids and nitric oxide in endotoxin-induced hyporesponsiveness of equine digital blood vessels.Equine veterinary journal, , Volume: 31, Issue:3, 1999
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin.British journal of pharmacology, , Volume: 126, Issue:6, 1999
Early inflammatory response correlates with the severity of injury.Critical care medicine, , Volume: 24, Issue:7, 1996
Role of prostaglandin H synthase-2 in prostaglandin E2 formation in rat carrageenin-induced pleurisy.Prostaglandins, , Volume: 51, Issue:1, 1996
Blunt injury augments interleukin-6 but not tumor necrosis factor in isolated, perfused rat hindlimbs.The Journal of trauma, , Volume: 37, Issue:1, 1994
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Stimulation of angiogenesis by substance P and interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists.British journal of pharmacology, , Volume: 110, Issue:1, 1993
Gastric toxicity and prostaglandin content in rats dosed with two chemically similar, nonsteroidal anti-inflammatory agents.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 202, Issue:2, 1993
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Ibuprofen modifies the inflammatory response of the murine lung to Pseudomonas aeruginosa.European journal of respiratory diseases, , Volume: 67, Issue:2, 1985
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Increased levels of 6-oxo-PGF1 alpha in human skin following ultraviolet B irradiation.British journal of clinical pharmacology, , Volume: 13, Issue:3, 1982
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Some features in prostaglandin synthesis of the cancer cells which metastasized into liver from intestinal cancer lesions.The Tohoku journal of experimental medicine, , Volume: 170, Issue:2, 1993
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[High-protein diet and high-grade proteinuria aggravate the progression of chronic renal failure in rats].Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, , Volume: 5, Issue:3, 2007
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Glomerular and hormonal responses to dietary protein intake in human renal disease.The American journal of physiology, , Volume: 253, Issue:6 Pt 2, 1987
Suppression of plasma renin activity by cyclosporine.The American journal of medicine, , Volume: 83, Issue:1, 1987
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Evidence of prostacyclin deficiency in the syndrome of hyporeninemic hypoaldosteronism.The New England journal of medicine, , Apr-17, Volume: 314, Issue:16, 1986
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Increased synthesis of systemic prostacyclin in cirrhotic patients.Gastroenterology, , Volume: 90, Issue:3, 1986
Stimulation of peritoneal synthesis of vasoactive prostaglandins during peritonitis in patients on continuous ambulatory peritoneal dialysis.European journal of clinical investigation, , Volume: 15, Issue:1, 1985
Prostacyclin synthesis is stimulated by a serum factor formed during coagulation.Thrombosis and haemostasis, , Feb-28, Volume: 49, Issue:1, 1983
Prostacyclin production by whole blood from children: impairment in the hemolytic uremic syndrome and excessive formation in chronic renal failure.Thrombosis research, , Apr-01, Volume: 30, Issue:1, 1983
Prostacyclin and thromboxane release from human peritoneal macrophages.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 12, 1983
Plasmatic TXB2 and 6-keto-PGF1 alpha levels during charcoal hemoperfusion in chronic renal failure patients.Prostaglandins, leukotrienes, and medicine, , Volume: 10, Issue:3, 1983
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Platelet microaggregates and release of endogenous prostacyclin during the initial phase of haemodialysis.Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, , Volume: 18, 1981
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Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2.Clinical science (London, England : 1979), , Volume: 95, Issue:1, 1998
Prostaglandin levels in human renal venous blood during renal arteriography.European journal of radiology, , Volume: 6, Issue:2, 1986
Altered 1-14C arachidonic acid metabolism in arterial wall from patients with renal cell carcinoma.The Journal of urology, , Volume: 135, Issue:5, 1986
[Changes of prostaglandins in kidney tissue in gentamicin-induced acute renal tubular injury in rats].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 20, Issue:1, 1998
Inhibition of thromboxane (Tx) synthesis by free radical scavengers.The Journal of trauma, , Volume: 28, Issue:4, 1988
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.Surgery, gynecology & obstetrics, , Volume: 165, Issue:5, 1987
[Relationship between the alteration of 6-keto-PGF1 alpha and TXB2 in cervical mucus of patients with threatened preterm labor and the efficacy of magnesium sulfate treatment].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 31, Issue:1, 2000
Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy.Gynecologic and obstetric investigation, , Volume: 50, Issue:4, 2000
[Relationship between PGI2, TXA2 and threatened preterm].Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, , Volume: 29, Issue:3, 1998
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Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin.American journal of obstetrics and gynecology, , Volume: 166, Issue:1 Pt 1, 1992
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Ritodrine infusion during late pregnancy: effects on fetal and placental blood flow, prostacyclin, and thromboxane.American journal of obstetrics and gynecology, , Apr-15, Volume: 151, Issue:8, 1985
Maternal prostacyclin, thromboxane, and placental blood flow.American journal of obstetrics and gynecology, , Mar-15, Volume: 145, Issue:6, 1983
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
Increased thromboxane A2 production at primary tumor site in metastasizing squamous cell carcinoma of the larynx.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:1, 1993
Prostaglandins in squamous cell carcinoma of the larynx: tumor and peritumor synthesis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Eicosanoids production in endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:4, 1992
Prostacyclin and thromboxane synthesis by endometrial cancer and leiomyomas.Prostaglandins, , Volume: 39, Issue:3, 1990
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Activated neutrophils impair gastric cytoprotection role of neutrophil elastase.Digestive diseases and sciences, , Volume: 45, Issue:6, 2000
Gastric prostacyclin (PGI2) prevents stress-induced gastric mucosal injury in rats primarily by inhibiting leukocyte activation.Prostaglandins & other lipid mediators, , Volume: 57, Issue:5-6, 1999
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Antithrombin III (AT III) prevents LPS-induced pulmonary vascular injury: novel biological activity of AT III.Seminars in thrombosis and hemostasis, , Volume: 23, Issue:6, 1997
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Plasma iPGE2 and i6-keto PGF1 alpha in the course of liver cirrhosis.Prostaglandins, , Volume: 53, Issue:1, 1997
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The role of systemic prostaglandins during human liver transplantation.Annals of the New York Academy of Sciences, , Jun-17, Volume: 723, 1994
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Increased synthesis of systemic prostacyclin in cirrhotic patients.Gastroenterology, , Volume: 90, Issue:3, 1986
Determination of 2,3-dinor-6-ketoprostaglandin F1 alpha in urine samples by liquid chromatography and radioimmunoassay.Journal of chromatography, , Dec-19, Volume: 383, Issue:2, 1986
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Prostacyclin decreases splanchnic vascular contractility in cirrhotic rats.Hepatobiliary & pancreatic diseases international : HBPD INT, , Volume: 13, Issue:4, 2014
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NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines.International journal of cancer, , Jun-10, Volume: 99, Issue:5, 2002
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.International journal of gastrointestinal cancer, , Volume: 32, Issue:1, 2002
Some features in prostaglandin synthesis of the cancer cells which metastasized into liver from intestinal cancer lesions.The Tohoku journal of experimental medicine, , Volume: 170, Issue:2, 1993
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Selective thromboxane A2 synthase inhibition by OKY-046 prevents cardiopulmonary dysfunction after ovine smoke inhalation injury.Anesthesiology, , Volume: 102, Issue:5, 2005
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Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock.Critical care medicine, , Volume: 29, Issue:7, 2001
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[Effects of tetramethylpyrazine on platelet functions of advanced cases of lung carcinoma].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 17, Issue:9, 1997
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Plasma prostaglandins in lung cancer.European journal of cancer & clinical oncology, , Volume: 24, Issue:6, 1988
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Inhibition of tumor cell metastasis by modulation of the vascular prostacyclin/thromboxane A2 system.Clinical & experimental metastasis, , Volume: 1, Issue:2
Abnormal prostanoid metabolism in lupus nephritis and the effects of a thromboxane A2 synthetase inhibitor, DP-1904.Lupus, , Volume: 5, Issue:2, 1996
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Haemostatic factors associated with vascular thrombosis in patients with systemic lupus erythematosus and the lupus anticoagulant.Annals of the rheumatic diseases, , Volume: 50, Issue:8, 1991
Effects of the lupus anticoagulant in patients with systemic lupus erythematosus on endothelial cell prostacyclin release and procoagulant activity.The Journal of investigative dermatology, , Volume: 90, Issue:5, 1988
Prostacyclin in systemic lupus and anticardiolipin syndrome.Annals of the rheumatic diseases, , Volume: 46, Issue:5, 1987
Essential fatty acids in diabetes and systemic lupus erythematosus (SLE) patients.Biochemical and biophysical research communications, , Apr-30, Volume: 128, Issue:2, 1985
Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis.Kidney international, , Volume: 60, Issue:2, 2001
Ureteral obstruction reverses glomerular proliferation in immune complex glomerulonephritis.The Journal of laboratory and clinical medicine, , Volume: 133, Issue:3, 1999
Improvement of renal function with selective thromboxane A2 synthetase inhibitor, DP-1904 in lupus nephritis.Advances in experimental medicine and biology, , Volume: 433, 1997
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The functional and structural changes of the glomerulus throughout the course of murine lupus nephritis.Journal of the American Society of Nephrology : JASN, , Volume: 3, Issue:4, 1992
The effects of a thromboxane synthase inhibitor, a prostacyclin analog and PGE1 on the nephritis of the NZB/W F1 mouse.Clinical nephrology, , Volume: 28, Issue:6, 1987
Acute effect of paraquat on lung fluid balance and prostanoid production in awake sheep.The American review of respiratory disease, , Volume: 134, Issue:6, 1986
Prostaglandin release and altered microvascular integrity after burn injury.The Journal of surgical research, , Volume: 31, Issue:4, 1981
Effect of post-treatment with granulocyte colony-stimulating factor on endotoxin-induced lung injury in sheep.Experimental lung research, , Volume: 24, Issue:1
Specific neutrophil elastase inhibitor does not attenuate acute lung injury induced by air embolism in awake sheep.Experimental lung research, , Volume: 22, Issue:6
Increased thromboxane A2 production at primary tumor site in metastasizing squamous cell carcinoma of the larynx.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:1, 1993
Plasma thromboxane A2 and prostacyclin concentrations in squamous cell carcinoma of the head and neck.Journal of surgical oncology, , Volume: 38, Issue:1, 1988
Prostaglandins in breast cancer: relationship to disease stage and hormone status.British journal of cancer, , Volume: 48, Issue:5, 1983
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Prostaglandin production by murine tumors as a predictor for therapeutic response to indomethacin.Cancer research, , Jun-01, Volume: 48, Issue:11, 1988
Cancer in mice: effects of prednisolone or mepacrine alone and with cytotoxic drugs.British journal of cancer, , Volume: 55, Issue:4, 1987
Survival of mice with NC carcinoma is unchanged by drugs that are thought to inhibit thromboxane synthesis or increase prostacyclin formation.British journal of cancer, , Volume: 54, Issue:2, 1986
Effect of indomethacin treatment on prostaglandin excretion and tissue phospholipid fatty acid composition in rats bearing mammotropic pituitary tumor, MtT-F4.Prostaglandins, leukotrienes, and medicine, , Volume: 23, Issue:2-3, 1986
Prostaglandin concentrations and prostaglandin synthetase activity in N-nitrosomethylurea-induced rat mammary adenocarcinoma.European journal of cancer & clinical oncology, , Volume: 19, Issue:6, 1983
Tumor prostaglandin levels correlate with edema around supratentorial meningiomas.Neurosurgery, , Volume: 33, Issue:2, 1993
"Ex vivo" release of eicosanoid from human brain tissue: its relevance in the development of brain edema.Neurosurgery, , Volume: 28, Issue:6, 1991
Production of prostaglandins and thromboxane by isolated cells from intracranial tumours.Journal of neurology, neurosurgery, and psychiatry, , Volume: 47, Issue:6, 1984
Tumor prostaglandin levels correlate with edema around supratentorial meningiomas.Neurosurgery, , Volume: 33, Issue:2, 1993
"Ex vivo" release of eicosanoid from human brain tissue: its relevance in the development of brain edema.Neurosurgery, , Volume: 28, Issue:6, 1991
Production of prostaglandins and thromboxane by isolated cells from intracranial tumours.Journal of neurology, neurosurgery, and psychiatry, , Volume: 47, Issue:6, 1984
[Intrauterine device-induced menorrhagia and endometrial content of prostacyclins].Zhonghua fu chan ke za zhi, , Volume: 27, Issue:3, 1992
Studies on IUD-induced menorrhagia and increased synthesis of prostacyclin in endometrium.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 8, Issue:4, 1988
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
A role for prostacyclin (PGi2) in excessive menstrual bleeding.Lancet (London, England), , Mar-07, Volume: 1, Issue:8219, 1981
Naproxen sodium in short-term prophylaxis of pure menstrual migraine: pathophysiological and clinical considerations.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, , Volume: 28 Suppl 2, 2007
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Relevance of prostaglandins in true menstrual migraine.Headache, , Volume: 29, Issue:4, 1989
Platelet function in classic migraine during attack-free periods.Acta neurologica Scandinavica, , Volume: 78, Issue:4, 1988
[Role of blood platelet aggregation in menstrual migraine].Minerva medica, , Jul-31, Volume: 78, Issue:14, 1987
Beta-adrenoceptor blockade, platelets, and rheologic factors.Cephalalgia : an international journal of headache, , Volume: 6 Suppl 5, 1986
Thromboxane synthetase inhibition: potential therapy in migraine.Headache, , Volume: 25, Issue:4, 1985
Salicylate treatment in Kawasaki disease: high dose or low dose?European journal of pediatrics, , Volume: 150, Issue:9, 1991
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Effects of current therapy of Kawasaki disease on eicosanoid metabolism.The American journal of cardiology, , Jun-01, Volume: 61, Issue:15, 1988
Antithrombin ameliorates endotoxin-induced organ dysfunction more efficiently when combined with danaparoid sodium than with unfractionated heparin.Intensive care medicine, , Volume: 31, Issue:8, 2005
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Effects of inhibitors of the activity of cyclo-oxygenase-2 on the hypotension and multiple organ dysfunction caused by endotoxin: a comparison with dexamethasone.British journal of pharmacology, , Volume: 124, Issue:3, 1998
Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns.Burns : journal of the International Society for Burn Injuries, , Volume: 24, Issue:8, 1998
Effect of calpain inhibitor I, an inhibitor of the proteolysis of I kappa B, on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat.British journal of pharmacology, , Volume: 121, Issue:4, 1997
[Thromboxane and prostacyclin imbalance in the pathogenesis of early damage after severe burns].Zhonghua yi xue za zhi, , Volume: 73, Issue:10, 1993
[Clinical study on main visceral damage and multiple organ failure (MOF) following severe burns].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 9, Issue:3, 1993
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
[Changes in plasma prostaglandin F2, thromboxane B2 and 6-keto-prostaglandin F1 alpha contents in patients suffering from multiple system organ failure after burns].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 8, Issue:1, 1992
[Clinical study of the pathogeneses of multiple organ failure after burns].Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns, , Volume: 8, Issue:1, 1992
A prospective clinical study on the pathogenesis of multiple organ failure in severely burned patients.Burns : journal of the International Society for Burn Injuries, , Volume: 18, Issue:1, 1992
Imbalance between plasma levels of thromboxane B2 and 6-keto-prostaglandin F1 alpha during subacute endotoxin-induced hyperdynamic sepsis or multiple organ failure syndrome in sheep.Circulatory shock, , Volume: 35, Issue:2, 1991
An increase in the ratio of thromboxane A2 to prostacyclin in association with increased blood pressure in patients on cyclosporine A.Prostaglandins, , Volume: 37, Issue:5, 1989
A study of the prostaglandin and thromboxane content of the central nervous tissues with the development of chronic relapsing allergic encephalomyelitis.Journal of neuroimmunology, , Volume: 10, Issue:3, 1986
[Prostaglandins in the cerebrospinal fluid of patients with multiple sclerosis].Neurologija, , Volume: 34, Issue:1-4, 1985
Arachidonic Acid-Dependent Pathway Inhibition in Platelets: its Role in Multiple Injury-Induced Coagulopathy and the Potential Mechanisms.Shock (Augusta, Ga.), , 01-01, Volume: 55, Issue:1, 2021
[Significance of the behavior of prostanoids in patients admitted in intensive care].Minerva anestesiologica, , Volume: 57, Issue:10, 1991
Panax quinquefolius saponins combined with dual antiplatelet drug therapy alleviate gastric mucosal injury and thrombogenesis through the COX/PG pathway in a rat model of acute myocardial infarction.PloS one, , Volume: 13, Issue:3, 2018
Microvascular pathological features and changes in related injury factors in a rat acute blood stasis model.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, , Volume: 37, Issue:1, 2017
Association of cyclooxygenase-2 genetic variant with cardiovascular disease.European heart journal, , Sep-01, Volume: 35, Issue:33, 2014
Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect.Arteriosclerosis, thrombosis, and vascular biology, , Volume: 34, Issue:9, 2014
The role of eNOS, iNOS, and NF-kappaB in upregulation and activation of cyclooxygenase-2 and infarct size reduction by atorvastatin.American journal of physiology. Heart and circulatory physiology, , Volume: 295, Issue:1, 2008
Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat.Journal of cardiovascular pharmacology and therapeutics, , Volume: 13, Issue:1, 2008
[Association of polymorphism of the prostacyclin synthase gene with myocardial infarction in Uigur population of Xinjiang].Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, , Volume: 25, Issue:6, 2008
Pioglitazone protects the myocardium against ischemia-reperfusion injury in eNOS and iNOS knockout mice.American journal of physiology. Heart and circulatory physiology, , Volume: 295, Issue:6, 2008
Aspirin before reperfusion blunts the infarct size limiting effect of atorvastatin.American journal of physiology. Heart and circulatory physiology, , Volume: 292, Issue:6, 2007
COX-2 mediates morphine-induced delayed cardioprotection via an iNOS-dependent mechanism.Life sciences, , Apr-25, Volume: 78, Issue:22, 2006
[Study on comparative pharmacology of series of Muskone].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 31, Issue:16, 2006
[Study on therapeutic effects of series of muskone on myocardial infarction canines].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 31, Issue:20, 2006
Cyclooxygenase-1 mediates the final stage of morphine-induced delayed cardioprotection in concert with cyclooxygenase-2.Journal of the American College of Cardiology, , May-17, Volume: 45, Issue:10, 2005
Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo.Anesthesiology, , Volume: 100, Issue:3, 2004
Delta-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits.American journal of physiology. Heart and circulatory physiology, , Volume: 283, Issue:5, 2002
Effect of cyclooxygenase-2 inhibitor (celecoxib) on the infarcted heart in situ.Pharmacology, , Volume: 63, Issue:1, 2001
Transcardiac 8-iso-prostaglandin F(2 alpha)generation from acute myocardial infarction heart: insight into abrupt reperfusion and oxidant stress.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 64, Issue:3, 2001
Myocardial protection by the nitroderivative of aspirin, NCX 4016: in vitro and in vivo experiments in the rabbit.Italian heart journal : official journal of the Italian Federation of Cardiology, , Volume: 1, Issue:2, 2000
The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation.Stroke, , Volume: 31, Issue:6, 2000
The effect of aspirin and two nitric oxide donors on the infarcted heart in situ.Life sciences, , Jul-07, Volume: 67, Issue:7, 2000
Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits.Proceedings of the National Academy of Sciences of the United States of America, , Aug-29, Volume: 97, Issue:18, 2000
[Soluble P-selectin - a marker of platelet activation and vessel wall injury: increase of soluble P-selectin in plasma of patients with myocardial infarction, massive atherosclerosis and primary pulmonary hypertension].Terapevticheskii arkhiv, , Volume: 72, Issue:4, 2000
Cyclooxygenase inhibition converts the effect of nitric oxide synthase inhibition from infarct size reduction to expansion in isolated rabbit hearts.Journal of molecular and cellular cardiology, , Volume: 31, Issue:6, 1999
Production of prostanoids and nitric oxide by infarcted heart in situ and the effect of aspirin.Biochemical and biophysical research communications, , Apr-13, Volume: 257, Issue:2, 1999
Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 61, Issue:1, 1999
Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:2, 1997
Arachidonic acid metabolites in acute myocardial infarction.Angiology, , Volume: 47, Issue:7, 1996
Implications of the prognostic importance of exercise-induced thromboxane formation in survivors of an acute myocardial infarction.Prostaglandins, , Volume: 49, Issue:4, 1995
More uses of known drugs.The Journal of the Association of Physicians of India, , Volume: 43, Issue:9, 1995
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Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction.The American journal of cardiology, , Jun-01, Volume: 73, Issue:15, 1994
Changes in 6 keto PGF1 alpha and TXB2 in patients with myocardial infarction.The Journal of the Association of Physicians of India, , Volume: 42, Issue:2, 1994
[Effects of methylflavonolamine on TXA2 and PGI2 plasma levels in rabbits with myocardial infarction].Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 14, Issue:3, 1993
[Improvement of prostacyclin-thromboxane A2 balance in patients with acute myocardial infarction by intermittent aspirin].Zhonghua xin xue guan bing za zhi, , Volume: 21, Issue:4, 1993
Regulation of atrial natriuretic peptide, thromboxane and prostaglandin production by androgen in elderly men with coronary heart disease.Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, , Volume: 8, Issue:4, 1993
[The effect of low dose aspirin on the platelet function in patients with acute myocardial infarction].Zhonghua nei ke za zhi, , Volume: 32, Issue:8, 1993
Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury.The Journal of pharmacology and experimental therapeutics, , Volume: 264, Issue:1, 1993
Balance of prostacyclin and thromboxane in offspring of parents with premature coronary arterial disease.International journal of cardiology, , Volume: 35, Issue:1, 1992
Protective effect of the new antiplatelet agent 2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo[1,5-a]pyridine on myocardial damage due to coronary occlusion and reperfusion in rabbit.Arzneimittel-Forschung, , Volume: 42, Issue:1, 1992
[Protective action of sophoridine on acute myocardial infarction in anesthetized dogs].Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 12, Issue:3, 1991
[Pharmacological correction by roxicam of the prostacyclin-thromboxane system in acute myocardial infarction complicated by heart failure].Kardiologiia, , Volume: 31, Issue:8, 1991
[Characteristics of disorders of thrombocytic hemostasis in patients with recurrent myocardial infarction].Kardiologiia, , Volume: 31, Issue:1, 1991
Prostacyclin production in myocardial infarction in the acute phase and during follow-up.Journal of internal medicine, , Volume: 229, Issue:2, 1991
Stimulation of prostacyclin synthesis by defibrotide: improved contractile recovery from myocardial "stunning".Journal of cardiovascular pharmacology, , Volume: 17, Issue:1, 1991
Captopril, an ACE inhibitor, for optimizing reperfusion after acute myocardial infarction.The Annals of thoracic surgery, , Volume: 52, Issue:4, 1991
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Prostaglandin I2 half-life regulated by high density lipoprotein is decreased in acute myocardial infarction and unstable angina pectoris.Circulation, , Volume: 81, Issue:6, 1990
[The role of n-3 polyunsaturated fatty acid on coronary heart disease].Zhonghua xin xue guan bing za zhi, , Volume: 18, Issue:5, 1990
Effects of exercise and ticlopidine on platelet function and prostanoids in patients with old myocardial infarction.Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, , Volume: 88, Issue:8, 1989
[Platelet functions in patients with acute myocardial infarction].Zhonghua xin xue guan bing za zhi, , Volume: 17, Issue:5, 1989
[Plasma TXB2, 6-keto-PGF1 alpha content and their ratio in myocardial infarction patients].Zhonghua xin xue guan bing za zhi, , Volume: 17, Issue:6, 1989
Essential fatty acid deficiency inhibits early but not late leukocyte infiltration in rabbit myocardial infarcts.Prostaglandins, , Volume: 38, Issue:1, 1989
[Thrombocyte function and the prostacyclin-thromboxane system in patients with acute myocardial infarct].Vrachebnoe delo, , Issue:3, 1988
Effects of coronary ischemia on lung fluid balance in conscious sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 65, Issue:2, 1988
The effects of trapidil and propranolol on platelet aggregation and prostacyclin-thromboxane balance following acute myocardial infarction in rabbits.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 8, Issue:4, 1988
Acute myocardial infarction: measurement of arachidonate end-products in whole blood as an index of platelet cyclo-oxygenase activity in vivo.Thrombosis research, , Oct-01, Volume: 48, Issue:1, 1987
Deficient prostacyclin formation after acute myocardial infarction.Lancet (London, England), , May-02, Volume: 1, Issue:8540, 1987
[Changes in circulatory thromboxane B2 and 6-keto-prostaglandin F1 alpha in acute myocardial infarction].Zhonghua nei ke za zhi, , Volume: 26, Issue:6, 1987
Platelet activation in unstable coronary disease.The New England journal of medicine, , Oct-16, Volume: 315, Issue:16, 1986
Development of an experimental model of acute myocardial infarction and the effects of a thromboxane synthetase inhibitor (OKY-046).American heart journal, , Volume: 112, Issue:4, 1986
In vivo production of prostacyclin and thromboxane in patients with acute myocardial infarction.British heart journal, , Volume: 55, Issue:6, 1986
[Effects of sodium beta-3,4-dihydroxyphenyl lactate and beta-phenyl lactic acid on prostacycline and thromboxane A2 contents in the plasma of rabbits after coronary artery occlusion].Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 7, Issue:6, 1986
Beneficial changes in prostacyclin and thromboxane A2 induced by ginsenosides in myocardial infarction and reperfusion injury in dogs.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 7, Issue:3, 1986
In vivo synthesis of thromboxane and prostacyclin in man in health and disease. Data from GC-MS measurements of major urinary metabolites.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 16, 1986
Platelet hyperactivity in acute myocardial infarction in man--effects of prostacyclin.Herz, , Volume: 11, Issue:2, 1986
Follow-up of prostaglandin plasma levels after acute myocardial infarction.American heart journal, , Volume: 109, Issue:2, 1985
Development of quantitative analysis of plasma thromboxane B2 by gas chromatography-mass spectrometry.Japanese circulation journal, , Volume: 49, Issue:3, 1985
The effects of nafazatrom in an acute occlusion-reperfusion model of canine myocardial injury.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 331, Issue:2-3, 1985
Cyclic nucleotides, prostaglandins, and ischemic heart disease.Advances in cyclic nucleotide and protein phosphorylation research, , Volume: 17, 1984
Decreased serum levels of a factor stimulating prostacyclin synthesis in acute myocardial infarction.Prostaglandins, leukotrienes, and medicine, , Volume: 16, Issue:3, 1984
Plasma 6-keto-PGF1 alpha in acute myocardial infarction.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:4, 1983
Urinary 6-oxo prostaglandin F1 alpha in myocardial infarction.British medical journal (Clinical research ed.), , Sep-10, Volume: 287, Issue:6394, 1983
[Biochemistry of coronary artery disease--prostaglandins].Rinsho byori. The Japanese journal of clinical pathology, , Volume: 31, Issue:8, 1983
Comparative effects of acetylsalicylic acid (ASA) and sulfinpyrazone on isoproterenol-induced heart damage.The Journal of pharmacology and experimental therapeutics, , Volume: 218, Issue:3, 1981
Role of a nonsteroidal anti-inflammatory agent, ibuprofen, in coronary revascularization after acute myocardial infarction.Basic research in cardiology, , Volume: 85, Issue:1
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis.International journal of gastrointestinal cancer, , Volume: 32, Issue:1, 2002
Dissociation between thromboxane generation and metastatic potential in cells from a murine fibrosarcoma. Studies with a selective thromboxane synthase inhibitor.International journal of cancer, , Apr-15, Volume: 39, Issue:4, 1987
Cancer in mice: effects of prednisolone or mepacrine alone and with cytotoxic drugs.British journal of cancer, , Volume: 55, Issue:4, 1987
Human platelet-tumor cell interactions vary with the tumor cell lines.Invasion & metastasis, , Volume: 6, Issue:6, 1986
Prostaglandin and thromboxane production in ovarian cancer tissue.Gynecologic and obstetric investigation, , Volume: 18, Issue:5, 1984
Prostaglandins in breast cancer: relationship to disease stage and hormone status.British journal of cancer, , Volume: 48, Issue:5, 1983
Breast cancer, its recurrence, and patient survival in relation to tumor prostaglandins.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 12, 1983
The possible role of circulating 6-oxo-PGF1 alpha in monitoring the growth and spread of malignant disease of the prostate.Progress in lipid research, , Volume: 20, 1981
Inhibition of tumor cell metastasis by modulation of the vascular prostacyclin/thromboxane A2 system.Clinical & experimental metastasis, , Volume: 1, Issue:2
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Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 112, Issue:5, 2012
Nitric oxide, prostanoids, cyclooxygenase, and angiogenesis in colon and breast cancer.Clinical cancer research : an official journal of the American Association for Cancer Research, , Volume: 7, Issue:11, 2001
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Early biochemical events in pneumococcal otitis media: arachidonic acid metabolites in middle ear fluid.The Annals of otology, rhinology, and laryngology, , Volume: 100, Issue:5 Pt 1, 1991
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Production of prostacyclin and thromboxane A2 in mononuclear cells from preeclamptic women.American journal of obstetrics and gynecology, , Volume: 169, Issue:5, 1993
Endothelial vasoactive mediators in preeclampsia.American journal of obstetrics and gynecology, , Volume: 169, Issue:1, 1993
Urinary excretion of 6-keto-PGF1 alpha TxB2 and PGE2 in a rat animal model for preeclampsia-like syndrome.Prostaglandins, , Volume: 46, Issue:2, 1993
Endothelium-derived prostacyclin: effect of serum from women with normal and hypertensive pregnancy.Clinical science (London, England : 1979), , Volume: 82, Issue:4, 1992
[Mechanism and effect of anisodamine on uteroplacental circulation in pregnancy-induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 27, Issue:4, 1992
[A trial of low-dose aspirin therapy in high-risk pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:7, 1992
Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia.American journal of obstetrics and gynecology, , Volume: 167, Issue:4 Pt 1, 1992
Sera from preeclamptic patients contain factor(s) that stimulate prostacyclin production by human endothelial cells.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:3, 1992
Umbilical and uterine Doppler velocimetry and prostaglandin levels in preeclampsia.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, , Volume: 11, Issue:2, 1992
[Urinary 11-dehydrothromboxane B2 and 6-keto-prostaglandin F1 alpha in normal pregnant women and in women complicated with pregnancy-induced hypertension].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:6, 1992
Preliminary evidence for homoeostatic mechanism regulating endothelin production in pre-eclampsia.Lancet (London, England), , Apr-20, Volume: 337, Issue:8747, 1991
The role of aggregation of platelets in pregnancy-induced hypertension: a comprehensive and longitudinal study.International journal of cardiology, , Volume: 33, Issue:1, 1991
The imbalance between thromboxane and prostacyclin in preeclampsia is associated with an imbalance between lipid peroxides and vitamin E in maternal blood.American journal of obstetrics and gynecology, , Volume: 165, Issue:6 Pt 1, 1991
[Low-dose aspirin preventing pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 26, Issue:6, 1991
Maternal and fetal atrial natriuretic peptide levels, maternal plasma renin activity, angiotensin II, prostacyclin and thromboxane A2 levels in normal and preeclamptic pregnancies.The Tohoku journal of experimental medicine, , Volume: 165, Issue:2, 1991
Sera from preeclamptic women increase the content of triglycerides and reduce the release of prostacyclin in cultured endothelial cells.Thrombosis research, , Aug-01, Volume: 63, Issue:3, 1991
[Prostaglandin E2, F2 alpha,6-keto-prostaglandin F1 alpha and thromboxane B2 in the placenta of normotensive women and women with pregnancy induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 24, Issue:6, 1989
Urinary excretion of prostacyclin metabolites in infants born after maternal preeclampsia or with birth asphyxia.Biology of the neonate, , Volume: 56, Issue:2, 1989
[Synthesis of prostaglandins and lipid peroxidation in pregnant women with gestosis].Akusherstvo i ginekologiia, , Issue:6, 1988
Urinary excretion of 6-keto prostaglandin F1 alpha in pre-eclampsia.Archives of gynecology and obstetrics, , Volume: 244, Issue:1, 1988
Prostacyclin and thromboxane in pregnancy-induced hypertension.Chinese medical journal, , Volume: 101, Issue:12, 1988
[Feto-placental microcirculation and pathologic changes of the chorionic villi in pregnancy-induced hypertension syndrome].Zhonghua yi xue za zhi, , Volume: 68, Issue:11, 1988
[Plasma 6-keto-prostaglandin F1 alpha and thromboxane B2 levels in normal pregnancy and pregnancy-induced hypertension].Zhonghua fu chan ke za zhi, , Volume: 23, Issue:1, 1988
Radioimmunoassay of thromboxane B2 and its preliminary applications.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 3, Issue:1, 1988
Reduced excretion of vasodilator prostaglandins in preeclampsia.Agents and actions. Supplements, , Volume: 22, 1987
[6-keto-prostaglandin F1 alpha and thromboxane B2 in the amniotic fluid and peripheral venous blood in healthy pregnant patients and in pregnant patients with pre-eclampsia].Zentralblatt fur Gynakologie, , Volume: 109, Issue:23, 1987
Placental prostacyclin production in normal and toxemic pregnancies.American journal of obstetrics and gynecology, , Volume: 154, Issue:1, 1986
Renal prostacyclin and thromboxane in normotensive and preeclamptic pregnant women and their infants.The Journal of clinical endocrinology and metabolism, , Volume: 63, Issue:6, 1986
Prostacyclin and thromboxane A2 in preeclamptic umbilical circulation.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 15, 1985
Preeclampsia: an imbalance in placental prostacyclin and thromboxane production.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
6-Keto prostaglandin F1 alpha, thromboxane B2, and 13,14-dihydro-15-keto prostaglandin F concentrations of normotensive and preeclamptic patients during pregnancy, delivery, and the postpartum period.American journal of obstetrics and gynecology, , Jan-01, Volume: 151, Issue:1, 1985
Effects of dihydralazine infusion on the fetoplacental blood flow and maternal prostanoids.Obstetrics and gynecology, , Volume: 65, Issue:1, 1985
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Failure of exogenous prostacyclin to change placental and fetal blood flow in preeclampsia.American journal of obstetrics and gynecology, , Mar-01, Volume: 151, Issue:5, 1985
Amniotic fluid 6-keto-prostaglandin F1 alpha and thromboxane B2 during labor.American journal of obstetrics and gynecology, , Nov-15, Volume: 150, Issue:6, 1984
Increased thromboxane A2 production but normal prostacyclin by the placenta in hypertensive pregnancies.Prostaglandins, , Volume: 27, Issue:1, 1984
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Amniotic fluid prostanoids in preeclampsia.Obstetrics and gynecology, , Volume: 64, Issue:1, 1984
Evidence that prostacyclin deficiency is a specific feature in preeclampsia.American journal of obstetrics and gynecology, , Mar-15, Volume: 148, Issue:6, 1984
Etiology of EPH-gestosis from the viewpoint of dynamics of vasoactive prostanoid, lipid peroxides and vitamin E.Nihon Sanka Fujinka Gakkai zasshi, , Volume: 35, Issue:5, 1983
[Studies on platelet function in toxemia of pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 35, Issue:7, 1983
Relation between umbilical prostacyclin production and blood-flow in the fetus.Lancet (London, England), , Apr-02, Volume: 1, Issue:8327, 1983
Prostacyclin and thromboxane during human pregnancy.Acta obstetricia et gynecologica Scandinavica. Supplement, , Volume: 113, 1983
Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies.American journal of obstetrics and gynecology, , Nov-01, Volume: 141, Issue:5, 1981
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
beta-Carotene attenuates peroxide-induced vasoconstriction in the human placenta.Journal of the Society for Gynecologic Investigation, , Volume: 4, Issue:2
Levels of stable metabolites of prostacyclin and thromboxane A2 and their ratio in normotensive and preeclamptic pregnant women during the antepartum and postpartum periods.The Journal of maternal-fetal medicine, , Volume: 9, Issue:3
[A trial of low-dose aspirin therapy in high-risk pregnancy].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 44, Issue:7, 1992
Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects.Obstetrics and gynecology, , Volume: 71, Issue:1, 1988
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Amniotic fluid prostaglandins do not reflect human fetal lung maturation.British journal of obstetrics and gynaecology, , Volume: 92, Issue:1, 1985
Maternal thromboxane, prostacyclin, and umbilical blood flow in humans.Obstetrics and gynecology, , Volume: 63, Issue:5, 1984
Maternal prostacyclin, thromboxane, and placental blood flow.American journal of obstetrics and gynecology, , Mar-15, Volume: 145, Issue:6, 1983
Plasma levels of prostaglandin metabolites in zinc-deficient female rats near term.The Journal of nutrition, , Volume: 113, Issue:4, 1983
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
Amniotic fluid prostacyclin and thromboxane in normal, preeclamptic, and some other complicated pregnancies.American journal of obstetrics and gynecology, , Nov-01, Volume: 141, Issue:5, 1981
Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders.Acta obstetricia et gynecologica Scandinavica, , Volume: 83, Issue:12, 2004
Normalization of vasoactive changes in preeclampsia precedes clinical recovery.Hypertension in pregnancy, , Volume: 21, Issue:1, 2002
Prostacyclin deficiency and reduced fetoplacental blood flow in pregnancy-induced hypertension and preeclampsia.Gynecologic and obstetric investigation, , Volume: 50, Issue:2, 2000
Vasoactive mediators in pregnancy-induced hypertensive disorders: a longitudinal study.American journal of obstetrics and gynecology, , Volume: 179, Issue:6 Pt 1, 1998
Do prostacyclin and thromboxane contribute to the "protective effect" of pregnancies with chronic hypertension? A preliminary prospective longitudinal study.American journal of obstetrics and gynecology, , Volume: 177, Issue:6, 1997
Intrauterine eicosanoid production in uncomplicated and hypertensive pregnancies: alterations of placental 12-hydroxyeicosatetraenoic acid.Advances in experimental medicine and biology, , Volume: 433, 1997
[Level of endothelin-1,2,6-keto-pgf1-alpha and atrial natriuretic peptide in serum of pregnant women with late hypertension].Polskie Archiwum Medycyny Wewnetrznej, , Volume: 95, Issue:6, 1996
Determination of mineral, parathyroid hormone, and 6-keto-prostaglandin-F1 alpha levels in pregnant women with hypertension and pre-eclampsia.Singapore medical journal, , Volume: 36, Issue:6, 1995
Hypertensive and normal pregnancy: a longitudinal study of blood pressure, distensibility of dorsal hand veins and the ratio of the stable metabolites of thromboxane A2 and prostacyclin in plasma.British journal of obstetrics and gynaecology, , Volume: 102, Issue:11, 1995
Adriamycin-related hypertension in pregnant rats: response to a thromboxane receptor antagonist.Clinical science (London, England : 1979), , Volume: 88, Issue:6, 1995
Plasma and urinary endothelin 1, prostacyclin metabolites and platelet consumption in pre-eclampsia and essential hypertensive pregnancy.Blood pressure, , Volume: 3, Issue:1-2, 1994
Ridogrel improves maternal/fetal homeostasis in an ovine model of pregnancy-induced hypertension.Prostaglandins, , Volume: 47, Issue:3, 1994
Correlation between umbilical artery resistance index, 6 ketoprostaglandin F1 alpha and thromboxane B2 in the fetoplacental compartment in patients with pregnancy induced hypertension.Prostaglandins, , Volume: 45, Issue:6, 1993
The effect of acetaminophen on prostacyclin production in pregnant women.American journal of obstetrics and gynecology, , Volume: 168, Issue:4, 1993
Prostacyclin, thromboxane and antioxidant levels in pregnancy-induced hypertension.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 50, Issue:3, 1993
Nifedipine increases urinary excretion of prostacyclin metabolite in hypertensive pregnancy.Pharmacology & toxicology, , Volume: 69, Issue:1, 1991
Endothelins in perinatal biology.Seminars in perinatology, , Volume: 15, Issue:1, 1991
[Changes in parameters of hemorheology and circulation 6-keto-PGF1 alpha and TXB2 in dilated cardiomyopathy].Zhonghua nei ke za zhi, , Volume: 30, Issue:4, 1991
Low-dose aspirin. II. Relationship of angiotensin II pressor responses, circulating eicosanoids, and pregnancy outcome.American journal of obstetrics and gynecology, , Volume: 163, Issue:6 Pt 1, 1990
Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.The New England journal of medicine, , Aug-10, Volume: 321, Issue:6, 1989
Prostacyclin and thromboxane in pregnancy-induced hypertension.Chinese medical journal, , Volume: 101, Issue:12, 1988
Altered excretion of prostaglandin and thromboxane metabolites in pregnancy-induced hypertension.Hypertension (Dallas, Tex. : 1979), , Volume: 11, Issue:6 Pt 1, 1988
[Basic and clinical studies of angiotensin II pressor responsiveness in pregnancy-induced-hypertension].Nihon Sanka Fujinka Gakkai zasshi, , Volume: 40, Issue:8, 1988
Plasma and amniotic fluid prostacyclin and thromboxane in mild pregnancy-induced hypertension.American journal of perinatology, , Volume: 4, Issue:2, 1987
Evaluation of platelet function in pregnancy. Comparative studies in non-smokers and smokers.Thrombosis research, , Apr-15, Volume: 46, Issue:2, 1987
Decreased prostacyclin biosynthesis preceding the clinical manifestation of pregnancy-induced hypertension.Circulation, , Volume: 75, Issue:5, 1987
Beneficial effects of U-63,557A, a thromboxane synthetase inhibitor, in an ovine model of pregnancy-induced hypertension.American journal of obstetrics and gynecology, , Volume: 157, Issue:1, 1987
Altered angiotensin-prostanoid interactions in umbilical arteries in pregnancy-induced hypertension.Scandinavian journal of clinical and laboratory investigation. Supplementum, , Volume: 184, 1986
Prostacyclin and thromboxane in gynecology and obstetrics.American journal of obstetrics and gynecology, , Jun-01, Volume: 152, Issue:3, 1985
Prostacyclin in normal and hypertensive pregnancy.American journal of obstetrics and gynecology, , Nov-15, Volume: 153, Issue:6, 1985
Evidence that prostacyclin deficiency is a specific feature in preeclampsia.American journal of obstetrics and gynecology, , Mar-15, Volume: 148, Issue:6, 1984
Increased thromboxane A2 production but normal prostacyclin by the placenta in hypertensive pregnancies.Prostaglandins, , Volume: 27, Issue:1, 1984
Plasma prostaglandins during the intravenous infusion of angiotensin II in pregnant women.American journal of obstetrics and gynecology, , Dec-15, Volume: 150, Issue:8, 1984
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Plasma prostanoids in pregnancy-induced hypertension.British journal of obstetrics and gynaecology, , Volume: 89, Issue:8, 1982
Decrease prostacyclin production: a characteristic of chronic placental insufficiency syndromes.Lancet (London, England), , May-23, Volume: 1, Issue:8230, 1981
Intrauterine infection and the effects of inflammatory mediators on prostaglandin production by myometrial cells from pregnant women.American journal of obstetrics and gynecology, , Volume: 174, Issue:2, 1996
Increased prostaglandin concentrations in the cervical mucus of pregnant women with bacterial vaginosis.Prostaglandins, , Volume: 43, Issue:2, 1992
Prostacyclin release and cytotoxicity of peritoneal cells are inversely related in pregnant and non-pregnant mice infected with herpes simplex virus.American journal of reproductive immunology (New York, N.Y. : 1989), , Volume: 20, Issue:4, 1989
Prostacyclin and hormone levels in patients with symptoms of miscarriage and infection.Medicinski pregled, , Volume: 55, Issue:9-10
Signs of platelet activation, but not lipid peroxidation, in fetal blood associated with functional and structural umbilicoplacental lesions in pregnancies complicated by impaired glucose metabolism.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, , Volume: 12, Issue:3, 2002
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
High glucose levels modulate eicosanoid production in uterine and placental tissue from non-insulin-dependent diabetic rats during late pregnancy.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 58, Issue:6, 1998
Nitric oxide modulates placental prostanoid production from late pregnant non-insulin-dependent diabetic rat.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 59, Issue:5, 1998
Eicosanoid production by placental and amnion tissues from control and non-insulin-dependent diabetic rats. Influence of oxytocin in the incubating medium.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:6, 1997
Reduced thromboxane receptor affinity and vasoconstrictor responses in placentae from diabetic pregnancies.Placenta, , Volume: 15, Issue:8, 1994
Placental thromboxane and prostacyclin production in an ovine diabetic model.American journal of obstetrics and gynecology, , Volume: 163, Issue:6 Pt 1, 1990
Influence of an alpha-1-adrenoceptor antagonist, nicergoline, on placental prostanoid production in streptozotocin-induced diabetic pregnant rats.Biology of the neonate, , Volume: 57, Issue:3-4, 1990
Eicosanoid production and transfer in the placenta of the diabetic pregnancy.Prostaglandins, , Volume: 40, Issue:2, 1990
Increase in uterine prostaglandin E2, F2 alpha, prostacyclin and stability in thromboxane A2 production during late pregnancy in streptozotocin-induced diabetic rats.Prostaglandins, , Volume: 37, Issue:6, 1989
Delayed effects of experimental maternal diabetes on plasma cholesterol level and vascular prostacyclin synthesis in the offspring.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 179, Issue:4, 1985
Abnormalities in vascular arachidonic acid metabolism in the infant of the diabetic mother.British medical journal (Clinical research ed.), , Jun-08, Volume: 290, Issue:6483, 1985
[Effect of obstetrical manipulations on the prostaglandin content of the uterus].Zentralblatt fur Gynakologie, , Volume: 107, Issue:8, 1985
Amniotic fluid prostaglandins do not reflect human fetal lung maturation.British journal of obstetrics and gynaecology, , Volume: 92, Issue:1, 1985
Plasma six-keto-prostaglandin F1 alpha and endocrine pancreatic function in the newborn infant of the diabetic mother.Biology of the neonate, , Volume: 48, Issue:2, 1985
Prostacyclin in complicated pregnancies.American journal of obstetrics and gynecology, , Nov-15, Volume: 147, Issue:6, 1983
Maternal plasma prostacyclin concentration in pre-eclampsia and other pregnancy complications.British journal of obstetrics and gynaecology, , Volume: 88, Issue:10, 1981
Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion.Clinical & experimental metastasis, , Volume: 19, Issue:7, 2002
Biochemical markers and skeletal metabolism in carcinoma of the prostate. Use of decision matrix theory and ROC analysis.British journal of urology, , Volume: 57, Issue:6, 1985
The possible role of circulating 6-oxo-PGF1 alpha in monitoring the growth and spread of malignant disease of the prostate.Progress in lipid research, , Volume: 20, 1981
Role of prostaglandins on mechanical scratching-induced cutaneous barrier disruption in mice.Experimental dermatology, , Volume: 16, Issue:6, 2007
Prostaglandin D2 and prostaglandin E2 accelerate the recovery of cutaneous barrier disruption induced by mechanical scratching in mice.European journal of pharmacology, , Jul-25, Volume: 518, Issue:1, 2005
Prostanoid DP1 receptor agonist inhibits the pruritic activity in NC/Nga mice with atopic dermatitis.European journal of pharmacology, , Nov-28, Volume: 505, Issue:1-3, 2004
Decreased pulmonary vasoreactivity in an animal model of chronic Pseudomonas pneumonia.The American review of respiratory disease, , Volume: 142, Issue:1, 1990
Effect of cyclooxygenase blockade on gas exchange and hemodynamics in Pseudomonas pneumonia.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 63, Issue:5, 1987
Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model.Circulatory shock, , Volume: 21, Issue:3, 1987
Comparison of regional pulmonary perfusion in lobar pneumonia during high frequency and conventional mechanical ventilation in sheep.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 34, Issue:3 ( Pt 1), 1987
Comparison of the postburn hyperdynamic state and changes in lung function (effect of wound bacterial content).Surgery, , Volume: 100, Issue:5, 1986
Effects of ibuprofen on a pig Pseudomonas ARDS model.The Journal of surgical research, , Volume: 40, Issue:5, 1986
Ibuprofen modifies the inflammatory response of the murine lung to Pseudomonas aeruginosa.European journal of respiratory diseases, , Volume: 67, Issue:2, 1985
[The content of thromboxane B2 and 6-ketoprostaglandin F1 alpha of the blood plasma in patients with psoriasis and children with allergic dermatoses].Vestnik dermatologii i venerologii, , Issue:1, 1989
Cyclosporine and urinary prostaglandins.Transplantation proceedings, , Volume: 20, Issue:3 Suppl 3, 1988
Prostaglandins in human skin disease.The British journal of dermatology, , Volume: 109 Suppl 25, 1983
Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness.Journal of virology, , Volume: 78, Issue:19, 2004
Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep.The European respiratory journal, , Volume: 20, Issue:4, 2002
Intratracheal administration of DBcAMP attenuates edema formation in phosgene-induced acute lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 80, Issue:1, 1996
Hepatic involvement in pancreatitis-induced lung damage.The American journal of physiology, , Volume: 270, Issue:1 Pt 1, 1996
Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase.Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, , Volume: 10, Issue:3, 1995
[Vasoactive intestinal polypeptide prevents injury of pulmonary vascular permeability due to xanthine with xanthine oxidase].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 17, Issue:4, 1995
Role of the bronchial circulation in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 76, Issue:1, 1994
Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:1, 1993
Thromboxane receptor stimulation/inhibition and perfusion redistribution after acute lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 75, Issue:5, 1993
Pentafraction reduces the lung lymph response after endotoxin administration in the ovine model.Circulatory shock, , Volume: 36, Issue:2, 1992
Eicosanoid balance and perfusion redistribution of oleic acid-induced acute lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:5, 1992
Pretreatment with catalase or dimethyl sulfoxide protects alloxan-induced acute lung edema in dogs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:4, 1992
Release of von Willebrand factor antigen (vWF:Ag) and eicosanoids during acute injury to the isolated rat lung.The American review of respiratory disease, , Volume: 145, Issue:6, 1992
Evidence of acute inflammatory response in reexpansion pulmonary edema.Chest, , Volume: 101, Issue:1, 1992
OKY-046 prevents increases in LTB4 and pulmonary edema in phorbol ester-induced lung injury in dogs.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 73, Issue:6, 1992
Ridogrel prevents the thromboxane-mediated pressor response and oedema induced by hydrogen peroxide in isolated rabbit lungs.European journal of pharmacology, , Aug-16, Volume: 201, Issue:1, 1991
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.Annals of surgery, , Volume: 212, Issue:6, 1990
Cyclooxygenase inhibition in lungs or in neutrophils attenuates neutrophil-dependent edema in rat lungs perfused with phorbol myristate acetate.The Journal of pharmacology and experimental therapeutics, , Volume: 251, Issue:3, 1989
Hemodynamic responses to acute hypoxia, hypobaria, and exercise in subjects susceptible to high-altitude pulmonary edema.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 67, Issue:5, 1989
Acute cigarette smoke exposure causes lung injury in rabbits treated with ibuprofen.Experimental lung research, , Volume: 13, Issue:2, 1987
Neutrophil depletion does not prevent lung edema after endotoxin infusion in goats.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 62, Issue:1, 1987
Involvement of thromboxane in injury to isolated rat lungs perfused with phorbol myristate acetate in the presence and absence of neutrophils.Toxicology and applied pharmacology, , Volume: 91, Issue:1, 1987
The pulmonary lesion of smoke inhalation in an ovine model.Circulatory shock, , Volume: 18, Issue:4, 1986
Ibuprofen prevents synthetic smoke-induced pulmonary edema.The American review of respiratory disease, , Volume: 134, Issue:6, 1986
Mechanisms of interaction between oxygen and granulocytes in hyperoxic lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 58, Issue:4, 1985
Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid.British journal of pharmacology, , Volume: 84, Issue:2, 1985
Effects of OKY-046, a selective thromboxane synthetase inhibitor, on endotoxin-induced lung injury in unanesthetized sheep.The American review of respiratory disease, , Volume: 132, Issue:3, 1985
Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Formation of prostanoids during intravascular complement activation in the rabbit.British journal of pharmacology, , Volume: 84, Issue:2, 1985
Effect of endotoxemia on hypoxic pulmonary vasoconstriction in unanesthetized sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 58, Issue:5, 1985
Lung edema due to hydrogen peroxide is independent of cyclooxygenase products.Journal of applied physiology: respiratory, environmental and exercise physiology, , Volume: 56, Issue:4, 1984
Platelet-activating factor raises airway and vascular pressures and induces edema in lungs perfused with platelet-free solution.The American review of respiratory disease, , Volume: 129, Issue:5, 1984
The effect of prostacyclin on increased hydraulic conductivity of pulmonary exchange vessels following microembolization in dogs.Microvascular research, , Volume: 26, Issue:2, 1983
Modification of inflammatory response to aspiration with ibuprofen.The American journal of physiology, , Volume: 243, Issue:6, 1982
Effects of ulinastatin, an antiprotease, on alloxan-induced lung injury in dogs.Clinical therapeutics, , Volume: 14, Issue:3
Effects of a fish oil diet on pigs' cardiopulmonary response to bacteremia.JPEN. Journal of parenteral and enteral nutrition, , Volume: 15, Issue:2
Effect of contrast media on the formation of prostacyclin in isolated rat lungs.Acta radiologica: diagnosis, , Volume: 26, Issue:6
Effects of Cydonia oblonga Miller extracts on blood hemostasis, coagulation and fibrinolysis in mice, and experimental thrombosis in rats.Journal of ethnopharmacology, , May-28, Volume: 154, Issue:1, 2014
[The effects of lupus anticoagulant on pulmonary thromboembolism].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 27, Issue:11, 2004
[Changes of the platelet function and serum anticardiolipin antibody in patients with pulmonary thromboembolism].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 27, Issue:11, 2004
Effect of BM-573 [N-terbutyl-N'-[2-(4'-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a dual thromboxane synthase inhibitor and thromboxane receptor antagonist, in a porcine model of acute pulmonary embolism.The Journal of pharmacology and experimental therapeutics, , Volume: 310, Issue:3, 2004
[Changes of blood vessel active substances in acute pulmonary embolism induced by echinococus granulous cyst in rabbits].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 25, Issue:10, 2002
Coronary constriction and consequent cardiodepression in pulmonary embolism are mediated by pulmonary big endothelin and enhanced in early endothelial dysfunction.Critical care medicine, , Volume: 26, Issue:3, 1998
Prostanoid production and pulmonary hypertension after fat embolism are not modified by methylprednisolone.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 38, Issue:5, 1991
Corticosteroids do not inhibit acute pulmonary response to fat embolism.Canadian journal of anaesthesia = Journal canadien d'anesthesie, , Volume: 37, Issue:4 Pt 2, 1990
[Preliminary observation on plasma level of 5-HT, TXB2 and 6-keto-PGF1 alpha in TEPH].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 10, Issue:5, 1988
Pulmonary embolism: analysis of endothelial pore sizes in canine lung.The American journal of physiology, , Volume: 255, Issue:5 Pt 2, 1988
Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect.The American journal of physiology, , Volume: 252, Issue:3 Pt 2, 1987
Effects of dibutyryl cAMP on pulmonary air embolism-induced lung injury in awake sheep.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 63, Issue:6, 1987
Effect of thromboxane synthetase inhibitors (OKY-046, OKY-1580) on experimentally induced air embolism in anesthetized dogs.Prostaglandins, leukotrienes, and medicine, , Volume: 21, Issue:2, 1986
Effects of Y-20811, a long-lasting thromboxane synthetase inhibitor, on thromboxane production and platelet function.Thrombosis research, , Aug-15, Volume: 43, Issue:4, 1986
Prostaglandin production in patients with pulmonary embolism.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
The effect of prostacyclin infusion on increased pulmonary vascular permeability following microembolization in dogs.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
The release of thromboxane A2 and prostacyclin following experimental acute pulmonary embolism.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
The effect of prostacyclin on increased hydraulic conductivity of pulmonary exchange vessels following microembolization in dogs.Microvascular research, , Volume: 26, Issue:2, 1983
The involvement of prostaglandins and thromboxanes in the response to pulmonary embolism in anaesthetized rabbits and isolated perfused lungs.Thrombosis research, , Apr-01, Volume: 30, Issue:1, 1983
Circulating negative inotropic agent(s) following pulmonary embolism.Surgery, , Volume: 91, Issue:4, 1982
[Effect of hypoxemia and pulmonary thromboembolism on plasma levels of 6-keto PGF 1 alpha, TxB, histamine and serotonin in anesthetized dogs (author's transl)].Nihon Kyobu Shikkan Gakkai zasshi, , Volume: 19, Issue:8, 1981
Treatment of pulmonary embolism with positive end-expiratory pressure and prostaglandin E1.Surgery, gynecology & obstetrics, , Volume: 153, Issue:2, 1981
The release of thromboxane B2 and 6-keto-PGF1 alpha following pulmonary embolism.Panminerva medica, , Volume: 31, Issue:4
Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine.Shock (Augusta, Ga.), , Volume: 2, Issue:5, 1994
The in vitro synthesis and degradation of prostaglandins during the development of bleomycin-induced pulmonary fibrosis in hamsters.Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:1, 1983
Thromboxane and prostacyclin (epoprostenol) during exercise in diffuse pulmonary fibrosis.Lancet (London, England), , Nov-27, Volume: 2, Issue:8309, 1982
[Changes of neurotransmitter endothelin, thromboxance B2 and 6-keto-prostaglandin F1 alpha in patients with chronic pulmonary heart disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University, , Volume: 30, Issue:6, 2010
Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin.American journal of medical genetics. Part A, , Volume: 152A, Issue:8, 2010
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[The interaction of some active and immunological factors in blood in the development of chronic cor pulmonale].Zhonghua nei ke za zhi, , Volume: 31, Issue:3, 1992
[Observations on levels of TXA2 and PGI2 and the generation of platelet MDA in patients with chronic cor pulmonale].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 10, Issue:2, 1987
[Quantitive study of 6-keto-prostaglandin F1 alpha and thromboxane B2 in human pulp].Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, , Volume: 34, Issue:4, 1999
Immunohistochemical demonstration of prostaglandins E2, F2 alpha, and 6-keto-prostaglandin F1 alpha in rat dental pulp with experimentally induced inflammation.Journal of endodontics, , Volume: 22, Issue:11, 1996
Involvement of arachidonic acid metabolites in increases in vascular permeability in experimental dental pulpal inflammation in the rat.Archives of oral biology, , Volume: 34, Issue:7, 1989
Arachidonic-acid metabolism in normal and experimentally-inflamed rat dental pulp.Archives of oral biology, , Volume: 32, Issue:10, 1987
Stability of prostacyclin in human and rabbit whole blood and plasma.Thrombosis research, , Aug-15, Volume: 43, Issue:4, 1986
Thrombotic thrombocytopenic purpura: treatment with nafazatrom.Clinical and laboratory haematology, , Volume: 6, Issue:2, 1984
Prostacyclin and thromboxane A2 in thrombotic thrombocytopenic purpura.British medical journal (Clinical research ed.), , Nov-21, Volume: 283, Issue:6303, 1981
Prostacyclin and haemolytic, thrombocytopenic microangiopathy.Lancet (London, England), , Sep-05, Volume: 2, Issue:8245, 1981
The role of prostaglandins E2 and F2 alpha in ultraviolet radiation-induced cortical cataracts in vivo.Investigative ophthalmology & visual science, , Volume: 37, Issue:8, 1996
Radiation hepatology of the rat: association of the production of prostacyclin with radiation-induced hepatic fibrosis.Radiation research, , Volume: 145, Issue:1, 1996
Amelioration of radiation nephropathy by acetylsalicylic acid.International journal of radiation biology, , Volume: 67, Issue:5, 1995
Corticosteroids prevent acute lung dysfunction caused by thoracic irradiation in unanesthetized sheep.The American review of respiratory disease, , Volume: 138, Issue:5, 1988
Effect of ionizing radiation on prostaglandins and gastric secretion in rhesus monkeys.Radiation research, , Volume: 110, Issue:2, 1987
Thromboxane and prostacyclin synthesis following whole body irradiation in rats.Journal of applied physiology: respiratory, environmental and exercise physiology, , Volume: 57, Issue:3, 1984
Anti-CENP-B and anti-TOPO-1-containing sera from systemic sclerosis-related diseases with Raynaud's phenomenon induce vascular endothelial cell senescence not via classical p53-p21 pathway.Clinical rheumatology, , Volume: 37, Issue:3, 2018
An imbalance in plasma prostanoids in patients with Raynaud's phenomenon and pulmonary vasospasm.The European respiratory journal, , Volume: 13, Issue:1, 1999
Treatment of severe Raynaud's syndrome by injection of autologous blood pretreated by heating, ozonation and exposure to ultraviolet light (H-O-U) therapy.International angiology : a journal of the International Union of Angiology, , Volume: 16, Issue:4, 1997
Plasma eicosanoids, platelet function and cold sensitivity.The British journal of surgery, , Volume: 76, Issue:4, 1989
Epoprostenol in patients with Raynaud's disease.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 33, Issue:1, 1988
Serum from patients with Raynaud's phenomenon inhibits prostacyclin production.The Journal of investigative dermatology, , Volume: 89, Issue:6, 1987
Prolonged remission in Raynaud's phenomenon after prostacyclin infusion.Scandinavian journal of rheumatology, , Volume: 15, Issue:4, 1986
Biosynthesis of thromboxane in patients with systemic sclerosis and Raynaud's phenomenon.British medical journal (Clinical research ed.), , Apr-19, Volume: 292, Issue:6527, 1986
Increased prostacyclin metabolites and decreased red cell deformability in patients with systemic sclerosis and Raynauds syndrome.Prostaglandins, leukotrienes, and medicine, , Volume: 17, Issue:1, 1985
Effect of dazoxiben, a thromboxane synthetase inhibitor on skin-blood flow following cold challenge in patients with Raynaud's phenomenon.European journal of clinical investigation, , Volume: 15, Issue:1, 1985
Dazoxiben, a thromboxane synthetase inhibitor, in Raynaud's phenomenon.Clinical pharmacology and therapeutics, , Volume: 36, Issue:1, 1984
Plasma 6 keto PGE1 alpha concentration in Raynaud's phenomenon.Prostaglandins and medicine, , Volume: 7, Issue:5, 1981
Catheter-based prostacyclin synthase gene transfer prevents in-stent restenosis in rabbit atheromatous arteries.Cardiovascular research, , Jan-01, Volume: 61, Issue:1, 2004
Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia.Biochemical pharmacology, , Oct-25, Volume: 52, Issue:8, 1996
[The experimental observation on the procedure of atherosclerotic restenosis following PTCA].Zhonghua nei ke za zhi, , Volume: 34, Issue:8, 1995
Effect of intraventricular haemorrhage and rebleeding following subarachnoid haemorrhage on CSF eicosanoids.Acta neurochirurgica, , Volume: 129, Issue:3-4, 1994
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Ridogrel in the setting of percutaneous transluminal coronary angioplasty.The American journal of cardiology, , Aug-15, Volume: 68, Issue:5, 1991
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Hemodynamic, platelet and clinical responses to prostacyclin in unstable angina pectoris.The American journal of cardiology, , May-01, Volume: 65, Issue:16, 1990
[Thromboxane analyses in patients with chronic inflammatory bowel diseases].Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, , Volume: 46, Issue:4, 1986
The pulmonary and systemic response to recurrent endotoxemia in the adult sheep.Surgery, , Volume: 100, Issue:5, 1986
Pulmonary prostacyclin is associated with less severe respiratory distress in preterm infants.Early human development, , Volume: 67, Issue:1-2, 2002
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Prostaglandins and echocardiography in the assessment of patent ductus arteriosus.Critical care medicine, , Volume: 14, Issue:5, 1986
Reduction of immunoreactive prostacyclin metabolite after paralysis in ventilated preterm infants.Early human development, , Volume: 13, Issue:1, 1986
Levels of 6-ketoprostaglandin F1 alpha in neonatal cerebrospinal fluid.Early human development, , Volume: 13, Issue:3, 1986
Ethamsylate reduces immunoreactive prostacyclin metabolite in low birthweight infants with respiratory distress syndrome.Early human development, , Volume: 14, Issue:3-4, 1986
[New aspects on the pathogenesis of patent ductus arteriosus in premature infants].Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, , Volume: 134, Issue:7, 1986
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Plasma 6-keto prostaglandin F1 alpha and thromboxane B2 in sick preterm neonates.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:2, 1985
Urinary excretion rates of 6-keto-PGF1 alpha in preterm infants recovering from respiratory distress with and without patent ductus arteriosus.Pediatric research, , Volume: 18, Issue:6, 1984
Effect of prenatal dexamethasone on immunoreactive 6-ketoprostaglandin F1 alpha levels in fetal rat lungs.Pediatric research, , Volume: 18, Issue:9, 1984
Diuresis and respiratory distress syndrome: physiologic mechanisms and therapeutic implications.The Journal of pediatrics, , Volume: 102, Issue:6, 1983
Increased plasma immunoreactive 6-keto-prostaglandin F1 alpha levels in newborns with idiopathic respiratory distress syndrome.Pediatric research, , Volume: 16, Issue:10, 1982
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Partial liquid ventilation with FC-77 suppresses the release of lipid mediators in rat acute lung injury model.Critical care medicine, , Volume: 32, Issue:10, 2004
Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock.Critical care medicine, , Volume: 29, Issue:7, 2001
Dose-response to inhaled aerosolized prostacyclin for hypoxemia due to ARDS.Chest, , Volume: 117, Issue:3, 2000
Response to inhaled nitric oxide in acute lung injury depends on distribution of pulmonary blood flow prior to its administration.American journal of respiratory and critical care medicine, , Volume: 159, Issue:2, 1999
[The effect of cyclooxygenase-2 inhibitor on acute lung injury].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 22, Issue:6, 1999
A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep.Respirology (Carlton, Vic.), , Volume: 4, Issue:2, 1999
Role of cyclooxygenase-2 in oleic acid-induced acute lung injury.American journal of respiratory and critical care medicine, , Volume: 160, Issue:4, 1999
Endothelin-1 and thromboxane A2 increase pulmonary vascular resistance in granulocyte-mediated lung injury.Critical care medicine, , Volume: 26, Issue:11, 1998
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Synergistic hemodynamic effects of low-dose endotoxin and acute lung injury.American journal of respiratory and critical care medicine, , Volume: 157, Issue:6 Pt 1, 1998
Eicosanoids and fat emulsions in acute respiratory distress syndrome patients.Nutrition (Burbank, Los Angeles County, Calif.), , Volume: 13, Issue:3, 1997
Leukocyte and platelet depletion with a blood cell separator: effects on lung injury after cardiac surgery with cardiopulmonary bypass.The Journal of thoracic and cardiovascular surgery, , Volume: 111, Issue:1, 1996
A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model.Critical care medicine, , Volume: 21, Issue:12, 1993
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
Effect of fast vs slow intralipid infusion on gas exchange, pulmonary hemodynamics, and prostaglandin metabolism.Chest, , Volume: 99, Issue:2, 1991
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[The study of thromboxane A2 and prostacyclin in oleic acid-induced lung injury in dogs].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 12, Issue:1, 1989
Thromboxane and prostacyclin release in adult respiratory distress syndrome.Intensive care medicine, , Volume: 13, Issue:3, 1987
Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model.Circulatory shock, , Volume: 21, Issue:3, 1987
[Protective effect of PGI2 on experimental ARDS and factors influencing it].Zhonghua wai ke za zhi [Chinese journal of surgery], , Volume: 25, Issue:12, 1987
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Lung permeability and hemodynamics during endotoxemia: effect of aprotinin.The Journal of surgical research, , Volume: 41, Issue:6, 1986
The pulmonary and systemic response to recurrent endotoxemia in the adult sheep.Surgery, , Volume: 100, Issue:5, 1986
Pulmonary microvascular injury induced by Pseudomonas aeruginosa cytotoxin in isolated rabbit lungs.Infection and immunity, , Volume: 52, Issue:3, 1986
Effects of ibuprofen on a pig Pseudomonas ARDS model.The Journal of surgical research, , Volume: 40, Issue:5, 1986
The development of a model of subacute lung injury after intra-abdominal infection.Surgery, , Volume: 96, Issue:2, 1984
Biochemical pathways of acute lung injury.Bulletin europeen de physiopathologie respiratoire, , Volume: 21, Issue:3
Arachidonic acid metabolites in human nasal polyps.Acta oto-laryngologica. Supplementum, , Volume: 501, 1993
Active immunization induces lung hyperresponsiveness in the guinea pig. Pharmacologic modulation and triggering role of the booster injection.The American review of respiratory disease, , Volume: 138, Issue:6, 1988
Nasal polyps and their content of arachidonic acid metabolites.New England and regional allergy proceedings, , Volume: 7, Issue:2
Lung vascular injury after administration of viable hemolysin-forming Escherichia coli in isolated rabbit lungs.The American review of respiratory disease, , Volume: 143, Issue:4 Pt 1, 1991
Plasma prostanoids in neonatal extracorporeal membrane oxygenation. Influence of meconium aspiration.The Journal of thoracic and cardiovascular surgery, , Volume: 101, Issue:4, 1991
The clinical significance of prostaglandins and thromboxane as mediators of septic shock.Klinische Wochenschrift, , Jan-15, Volume: 65, Issue:2, 1987
Prostaglandin and thromboxane levels during endotoxin-induced respiratory failure in pigs.Prostaglandins, leukotrienes, and medicine, , Volume: 28, Issue:3, 1987
Platelet function in acute respiratory failure.American journal of hematology, , Volume: 25, Issue:4, 1987
Thromboxane and prostacyclin in clinical acute respiratory failure.The Journal of surgical research, , Volume: 39, Issue:1, 1985
Role of serotonin in patients with acute respiratory failure.Annals of surgery, , Volume: 200, Issue:2, 1984
[Evaluation of various components of arachidonic acid metabolism of the subretinal fluid in aphakic eyes].Klinika oczna, , Volume: 90, Issue:6, 1988
[Thromboxane B2 and prostaglandin 6-keto-F1 alpha in the subretinal fluid].Klinika oczna, , Volume: 89, Issue:7, 1987
Prostacyclin and thromboxane A2 derivatives in rhegmatogenous subretinal fluid.Archives of ophthalmology (Chicago, Ill. : 1960), , Volume: 101, Issue:3, 1983
Arachidonic acid metabolism following aneurysm rupture. Evaluation of cerebrospinal fluid and serum concentration of 6-keto-prostaglandin F1 alpha and thromboxane B2 in patients with subarachnoid hemorrhage.Surgical neurology, , Volume: 27, Issue:3, 1987
Cisternal and lumbar CSF levels of arachidonate metabolites after subarachnoid haemorrhage: an assessment of the biochemical hypothesis of vasospasm.Acta neurochirurgica, , Volume: 84, Issue:3-4, 1987
[Arachidonic acid metabolism following aneurysm rupture].European archives of psychiatry and neurological sciences, , Volume: 236, Issue:2, 1986
Cisternal and lumbar CSF concentration of arachidonate metabolites in vasospasm following subarachnoid hemorrhage from ruptured aneurysm: biochemical and clinical considerations.Surgical neurology, , Volume: 24, Issue:4, 1985
Prostacyclin is a potent anti-mutagen.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 48, Issue:2, 1993
Prostaglandin production by murine tumors as a predictor for therapeutic response to indomethacin.Cancer research, , Jun-01, Volume: 48, Issue:11, 1988
Functional responses of tumor cells to phorbol esters: role for prostaglandins.Oncology, , Volume: 41, Issue:3, 1984
Prostaglandin levels of primary bone tumor tissues correlate with peritumoral edema demonstrated by magnetic resonance imaging.Cancer, , Jan-15, Volume: 79, Issue:2, 1997
Effects of interleukin-1 alpha on arachidonic acid metabolism in human osteosarcoma osteoblastic cells.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:1, 1993
Relationship of cAMP and calcium messenger systems in prostaglandin-stimulated UMR-106 cells.The Journal of biological chemistry, , Aug-05, Volume: 263, Issue:22, 1988
Plasma concentrations of thromboxane and prostacyclin metabolites in patients with bone tumors.The American journal of pediatric hematology/oncology, ,Spring, Volume: 7, Issue:1, 1985
Cyclo-oxygenase products of arachidonic acid metabolism in rat osteoblasts in culture.Calcified tissue international, , Volume: 35, Issue:3, 1983
Anti-CENP-B and anti-TOPO-1-containing sera from systemic sclerosis-related diseases with Raynaud's phenomenon induce vascular endothelial cell senescence not via classical p53-p21 pathway.Clinical rheumatology, , Volume: 37, Issue:3, 2018
Silica-associated systemic sclerosis is clinically, serologically and immunologically indistinguishable from idiopathic systemic sclerosis.The British journal of dermatology, , Volume: 123, Issue:6, 1990
Plasma eicosanoids, platelet function and cold sensitivity.The British journal of surgery, , Volume: 76, Issue:4, 1989
Serum from patients with Raynaud's phenomenon inhibits prostacyclin production.The Journal of investigative dermatology, , Volume: 89, Issue:6, 1987
Biosynthesis of thromboxane in patients with systemic sclerosis and Raynaud's phenomenon.British medical journal (Clinical research ed.), , Apr-19, Volume: 292, Issue:6527, 1986
Increased prostacyclin metabolites and decreased red cell deformability in patients with systemic sclerosis and Raynauds syndrome.Prostaglandins, leukotrienes, and medicine, , Volume: 17, Issue:1, 1985
Prostaglandins in human skin disease.The British journal of dermatology, , Volume: 109 Suppl 25, 1983
Demonstration of a range of inflammatory mediators released in trichostrongylosis of sheep.International journal for parasitology, , Volume: 21, Issue:3, 1991
Ibuprofen prevents Pasteurella hemolytica endotoxin-induced changes in plasma prostanoids and serotonin, and fever in sheep.Journal of veterinary pharmacology and therapeutics, , Volume: 8, Issue:4, 1985
Reduced progesterone and altered cotyledonary prostaglandin values induced by locoweed (Astragalus lentiginosus) in sheep.American journal of veterinary research, , Volume: 46, Issue:9, 1985
Effect of Ibuprofen on interleukin-1beta-induced abnormalities in hemodynamics and oxygen metabolism in rabbits.Shock (Augusta, Ga.), , Volume: 20, Issue:6, 2003
Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns.Burns : journal of the International Society for Burn Injuries, , Volume: 24, Issue:8, 1998
Beneficial effects of BAY u3405, a novel thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock.Pharmacology, , Volume: 49, Issue:6, 1994
A prospective clinical study on the pathogenesis of multiple organ failure in severely burned patients.Burns : journal of the International Society for Burn Injuries, , Volume: 18, Issue:1, 1992
[Plasma renin activity, angiotensin II, angiotensin converting enzyme, thromboxane A2 and prostacyclin I2 levels in pigs with severe hypoxia and hypercapnea and acidosis shock].Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, , Volume: 15, Issue:1, 1992
Protective effects of G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock.Journal of cardiovascular pharmacology, , Volume: 19, Issue:1, 1992
Interactions between platelet-activating factor and prostanoids during mesenteric ischemia-reperfusion-induced shock in the anesthetized dog.Circulatory shock, , Volume: 35, Issue:1, 1991
Platelet activating factor involvement in splanchnic artery occlusion shock in rats.European journal of pharmacology, , Jan-03, Volume: 192, Issue:1, 1991
Intestinal and arterial plasma thromboxane and prostacyclin levels in shock: effects of indomethacin.The Journal of surgical research, , Volume: 47, Issue:6, 1989
Thromboxane and prostacyclin release in adult respiratory distress syndrome.Intensive care medicine, , Volume: 13, Issue:3, 1987
Inhibition of thromboxane biosynthesis in splanchnic ischemia shock.Circulatory shock, , Volume: 18, Issue:2, 1986
Acute circulatory collapse caused by platelet-activating factor (PAF-acether) in dogs.European journal of pharmacology, , Jan-21, Volume: 86, Issue:3-4, 1983
[Cardio- and hemodynamics of dogs during the development of postischemic shock reaction].Fiziologicheskii zhurnal, , Volume: 35, Issue:4
Effects of recombinant human endothelial-derived interleukin-8 on hemorrhagic shock in rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 18, Issue:5, 1997
Amelioration by mercaptoethylguanidine of the vascular and energetic failure in haemorrhagic shock in the anesthetised rat.European journal of pharmacology, , Oct-29, Volume: 338, Issue:1, 1997
Effects of cyproheptadine on TXB2 and 6-keto-PGF1 alpha plasma levels in rabbits with hemorrhagic shock.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 15, Issue:3, 1994
Long-term hyperalimentation following hemorrhage/reperfusion injury induces intestinal prostanoid synthesis.Circulatory shock, , Volume: 40, Issue:2, 1993
Role of oxygen-derived free radicals on rat splanchnic eicosanoid production during acute hemorrhage.Prostaglandins, , Volume: 44, Issue:1, 1992
Hemodynamic, hematologic and eicosanoid mediated mechanisms in 7.5 percent sodium chloride treatment of uncontrolled hemorrhagic shock.Surgery, gynecology & obstetrics, , Volume: 175, Issue:4, 1992
Prolonged hemorrhagic shock decreases splanchnic prostacyclin synthesis.The Journal of surgical research, , Volume: 50, Issue:5, 1991
Protective effect of cloricromene, a coumarine derivative, in hypovolemic hemorrhagic shock in the rat.Journal of cardiovascular pharmacology, , Volume: 17, Issue:2, 1991
Splanchnic prostanoid production: effect of hemorrhagic shock.The Journal of surgical research, , Volume: 48, Issue:6, 1990
Reperfusion inhibits elevated splanchnic prostanoid production after hemorrhagic shock.Annals of surgery, , Volume: 212, Issue:6, 1990
Intestinal prostacyclin and thromboxane production in irreversible hemorrhagic shock.Circulatory shock, , Volume: 23, Issue:2, 1987
Effects of nafazatrom on cardiovascular, sympathetic, and endocrine responses to hemorrhagic shock in conscious rats.Circulatory shock, , Volume: 17, Issue:3, 1985
Role of neutrophil elastase in development of pulmonary vascular injury and septic shock in rats.Shock (Augusta, Ga.), , Volume: 30, Issue:4, 2008
Cyclooxygenase inhibitor blocks rebound response after NO inhalation in an endotoxin model.American journal of physiology. Heart and circulatory physiology, , Volume: 284, Issue:1, 2003
Prostacyclin is neither sufficient alone nor necessary to cause pulmonary dysfunction: results from infusions of prostacyclin and antiprostacyclin antibody in porcine septic shock.Critical care medicine, , Volume: 29, Issue:7, 2001
The cardiovascular hemodynamics and leukotriene kinetics during prostacyclin and anti-prostacyclin antibody infusions in septic shock.Shock (Augusta, Ga.), , Volume: 13, Issue:6, 2000
Is prostacyclin responsible for producing the hyperdynamic response during early sepsis?Critical care medicine, , Volume: 28, Issue:5, 2000
Inhibition of NF-kappaB activation by pyrrolidine dithiocarbamate prevents In vivo expression of proinflammatory genes.Circulation, , Sep-21, Volume: 100, Issue:12, 1999
Protective effect of tyrphostin AG-556 on shock induced by endotoxin or gram positive bacteria.Shock (Augusta, Ga.), , Volume: 12, Issue:2, 1999
The influence of heat shock protein 70 induction on hemodynamic variables in a porcine model of recurrent endotoxemia.Shock (Augusta, Ga.), , Volume: 7, Issue:5, 1997
Effect of calpain inhibitor I, an inhibitor of the proteolysis of I kappa B, on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat.British journal of pharmacology, , Volume: 121, Issue:4, 1997
G 619, a dual thromboxane synthase inhibitor and thromboxane A2 receptor antagonist, inhibits tumor necrosis factor-alpha biosynthesis.European journal of pharmacology, , Nov-03, Volume: 286, Issue:1, 1995
Effect of platelet activating factor antagonist (CV-3988) on 6-keto-PGF1 alpha and thromboxane B2 in dogs with experimental endotoxin-induced shock.The Journal of veterinary medical science, , Volume: 57, Issue:1, 1995
The effect of dietary nucleic acid deficiency and the administration of a nucleotide and nucleosides mixture solution on endotoxin shock in rats.Advances in experimental medicine and biology, , Volume: 370, 1994
A therapeutic effect of ulinastatin on endotoxin-induced shock in dogs--comparison with methylprednisolone.The Journal of veterinary medical science, , Volume: 56, Issue:4, 1994
Time course of systemic and renal plasma prostanoid concentrations and renal function in ovine hyperdynamic sepsis.Clinical science (London, England : 1979), , Volume: 86, Issue:5, 1994
Prior exposure to endotoxin exacerbates lipopolysaccharide-induced hypoxemia and alveolitis in anesthetized swine.Shock (Augusta, Ga.), , Volume: 2, Issue:5, 1994
[Septic shock and multiple organ failure in surgical intensive care. An animal experiment model on the analysis of pulmonary and intestinal dysfunction].Langenbecks Archiv fur Chirurgie, , Volume: 378, Issue:4, 1993
Effect of dibutyryl cyclic AMP on hemodynamics and chemical mediators in dogs with experimentally-induced endotoxic shock.The Journal of veterinary medical science, , Volume: 55, Issue:6, 1993
A novel leukotriene B4-receptor antagonist in endotoxin shock: a prospective, controlled trial in a porcine model.Critical care medicine, , Volume: 21, Issue:12, 1993
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Time course of various inflammatory mediators during recurrent endotoxemia.Biochemical pharmacology, , May-28, Volume: 43, Issue:10, 1992
Pentafraction reduces the lung lymph response after endotoxin administration in the ovine model.Circulatory shock, , Volume: 36, Issue:2, 1992
A PAF receptor antagonist, BN 52021, attenuates thromboxane release and improves survival in lethal canine endotoxemia.Circulatory shock, , Volume: 35, Issue:1, 1991
Imbalance between plasma levels of thromboxane B2 and 6-keto-prostaglandin F1 alpha during subacute endotoxin-induced hyperdynamic sepsis or multiple organ failure syndrome in sheep.Circulatory shock, , Volume: 35, Issue:2, 1991
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Protective effect of Y-20811, a long-lasting thromboxane synthetase inhibitor, on endotoxin shock in rabbits.Thrombosis research, , Feb-15, Volume: 57, Issue:4, 1990
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Inhibitory effects of anisodamine on endotoxin-induced prostaglandin production by cells in culture.Chinese medical journal, , Volume: 101, Issue:12, 1988
Inhibition of lipoxygenase (LOX) or of cyclooxygenase (COX) improves survival of rats in endotoxin shock.Biomedica biochimica acta, , Volume: 47, Issue:10-11, 1988
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The clinical significance of prostaglandins and thromboxane as mediators of septic shock.Klinische Wochenschrift, , Jan-15, Volume: 65, Issue:2, 1987
Leukotriene antagonist FPL 57231 prevents the acute pulmonary effects of Escherichia coli endotoxin in cats.Circulatory shock, , Volume: 21, Issue:2, 1987
Efficiency of prostacyclin in rabbit endotoxin shock.Progress in clinical and biological research, , Volume: 236A, 1987
The efficacy of dexamethasone and flunixin meglumine in treating endotoxin-induced changes in calves.Veterinary research communications, , Volume: 11, Issue:5, 1987
Changes of plasma levels of 6-keto-PGF1 alpha and TXB2 in rats during septic and endotoxic shock.Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao, , Volume: 2, Issue:1, 1987
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Low-dose dopamine preserves renal blood flow in endotoxin shocked dogs treated with ibuprofen.The Journal of surgical research, , Volume: 38, Issue:6, 1985
Changes in the plasma levels of PGE, PGF2 alpha and 6-keto-PGF1 alpha in canine endotoxic shock.Chinese medical journal, , Volume: 98, Issue:7, 1985
Prostanoid production by lipopolysaccharide-stimulated Kupffer cells.The Journal of surgical research, , Volume: 38, Issue:5, 1985
Elevated plasma 6-keto-prostaglandin F1 alpha in patients in septic shock.Critical care medicine, , Volume: 13, Issue:6, 1985
The role of thromboxane in primate endotoxin shock.The Journal of surgical research, , Volume: 39, Issue:2, 1985
Metabolic and cardiovascular effects of endotoxin infusion in conscious unrestrained rats: effects of methylprednisolone and BW755C.Circulatory shock, , Volume: 15, Issue:3, 1985
Thromboxane, prostacyclin, and the hemodynamic effects of graded bacteremic shock.Circulatory shock, , Volume: 16, Issue:4, 1985
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Sulindac does not preserve renal prostacyclin synthesis during endotoxemia.Prostaglandins, , Volume: 29, Issue:6, 1985
[Changes in the plasma 6-keto-PGF1 alpha level during canine endotoxic shock].Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, , Volume: 7, Issue:1, 1985
Prostacyclin biosynthesis and hypotension in relation to complement activation in rabbit endotoxic shock.Biomedica biochimica acta, , Volume: 43, Issue:8-9, 1984
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Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat.British journal of pharmacology, , Volume: 78, Issue:4, 1983
Beneficial effects of UK 37248, a thromboxane synthetase inhibitor, in experimental endotoxic shock in the rat.British journal of clinical pharmacology, , Volume: 15 Suppl 1, 1983
Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581.The Journal of pharmacology and experimental therapeutics, , Volume: 222, Issue:2, 1982
[Experimental investigation on the pathogenesis of endotoxin shock--the change of plasma serotonin, histamine, thromboxane B2 and 6-keto PGF1 alpha levels and modulation by indomethacin (author's transl)].Nihon Kyobu Shikkan Gakkai zasshi, , Volume: 20, Issue:2, 1982
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Antithrombin reduces compression-induced spinal cord injury in rats.Journal of neurotrauma, , Volume: 21, Issue:12, 2004
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Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury.Arzneimittel-Forschung, , Volume: 62, Issue:12, 2012
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Involvement of prostaglandin E receptor EP3 subtype and prostacyclin IP receptor in decreased acid response in damaged stomach.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, , Volume: 58, Issue:3, 2007
Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins.World journal of gastroenterology, , May-21, Volume: 12, Issue:19, 2006
Facilitation by endogenous prostaglandins of capsaicin-induced gastric protection in rodents through EP2 and IP receptors.The Journal of pharmacology and experimental therapeutics, , Volume: 304, Issue:3, 2003
Activated neutrophils impair gastric cytoprotection role of neutrophil elastase.Digestive diseases and sciences, , Volume: 45, Issue:6, 2000
Gastric antigen challenge releases gastrin and eicosanoids and protects against ethanol.The Journal of surgical research, , Volume: 70, Issue:1, 1997
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Influence of prednisolone on gastric alkaline response in rat stomach. A possible explanation for steroid-induced gastric lesion.Digestive diseases and sciences, , Volume: 30, Issue:12, 1985
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Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats.Digestive diseases and sciences, , Volume: 52, Issue:2, 2007
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Estrogen and isoflavone attenuate stress-induced gastric mucosal injury by inhibiting decreases in gastric tissue levels of CGRP in ovariectomized rats.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 292, Issue:2, 2007
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Adaptive cytoprotection mediated by prostaglandin I(2) is attributable to sensitization of CRGP-containing sensory nerves.Gastroenterology, , Volume: 120, Issue:1, 2001
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Effect of proximal selective vagotomy on gastric prostaglandin content in the Shay-rat ulcer model.Acta physiologica Hungarica, , Volume: 74, Issue:1, 1989
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Capsular type-specific polysaccharide partially inhibits group B Streptococcus-induced pulmonary hypertension.The American review of respiratory disease, , Volume: 148, Issue:1, 1993
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Pacing-induced myocardial ischemia does not affect the endothelial release of coagulant and fibrinolytic factors into the coronary circulation.Clinical cardiology, , Volume: 14, Issue:3, 1991
The role of prostacyclin in the mesenteric traction syndrome during anesthesia for abdominal aortic reconstructive surgery.Annals of surgery, , Volume: 209, Issue:3, 1989
Adenosine cardioprotection study in clinical setting of paroxysmal supraventricular tachycardia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 74, Issue:6, 2006
[Content of endogenous prostanoids in patients with paroxysmal supraventricular disorders of the heart rhythm].Kardiologiia, , Volume: 26, Issue:6, 1986
Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis.Journal of ethnopharmacology, , Feb-27, Volume: 152, Issue:1, 2014
High-mobility-group box protein 1A box reduces development of sodium laurate-induced thromboangiitis obliterans in rats.Journal of vascular surgery, , Volume: 57, Issue:1, 2013
[Changes in oxygen free radical and prostacyclin in thromboangiitis obliterans and its relationship with syndrome differentiation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:11, 1993
Clinical effectiveness of defibrotide in vaso-occlusive disorders and its mode of actions.Seminars in thrombosis and hemostasis, , Volume: 14 Suppl, 1988
Effects of arsenate and ergot alkaloid compounds on prostacyclin synthesis in human umbilical endothelium.Cell biology international reports, , Volume: 10, Issue:4, 1986
Prostacyclin and blood glucose levels in humans and rabbits.Prostaglandins, , Volume: 21, Issue:1, 1981
In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia.Thrombosis and haemostasis, , Jul-03, Volume: 112, Issue:1, 2014
[The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia].Zhonghua yi xue za zhi, , Jan-26, Volume: 90, Issue:4, 2010
Generation of arachidonic acid metabolites from stimulated whole blood in patients with chronic myeloproliferative disorders.Acta haematologica, , Volume: 85, Issue:2, 1991
Haemodynamic and haematologic effects of Acanthaster planci venom in dogs.Toxicon : official journal of the International Society on Toxinology, , Volume: 32, Issue:10, 1994
Thromboxane A2 accounts for bronchoconstriction but not for platelet sequestration and microvascular albumin exchanges induced by fMLP in the guinea pig lung.The Journal of pharmacology and experimental therapeutics, , Volume: 260, Issue:2, 1992
Evaluation of platelets and hemostasis during hemodialysis with six different membranes.Nephron, , Volume: 59, Issue:4, 1991
Antithrombotic activity of garlic: its inhibition of the synthesis of thromboxane-B2 during infusion of arachidonic acid and collagen in rabbits.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 41, Issue:2, 1990
Increased in vivo biosynthesis of prostacyclin and thromboxane A2 in chronic idiopathic thrombocytopenic purpura.British journal of haematology, , Volume: 72, Issue:3, 1989
Low-dose PGI2 prevents monocrotaline-induced thromboxane production and lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 60, Issue:2, 1986
Streptococcus pneumoniae-induced alterations in levels of circulating thromboxane and prostacyclin: dissociation from granulocytopenia, thrombocytopenia, and pulmonary leukostasis.The Journal of infectious diseases, , Volume: 153, Issue:1, 1986
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.Thrombosis research, , Jul-15, Volume: 43, Issue:2, 1986
Hemodialysis-associated platelet activation and thrombocytopenia.The American journal of medicine, , Volume: 78, Issue:4, 1985
In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat.Thrombosis research, , Oct-01, Volume: 32, Issue:1, 1983
Thromboxane synthesis by sources other than platelets in association with complement-induced pulmonary leukostasis and pulmonary hypertension in sheep.Circulation research, , Volume: 52, Issue:1, 1983
Contribution of complement activation to the rise in blood levels of 6-oxo-prostaglandin F1 alpha during endotoxin-induced hypotension in rabbits.European journal of pharmacology, , Apr-08, Volume: 79, Issue:1-2, 1982
Thromboxane and prostacyclin production during septic shock.Advances in shock research, , Volume: 7, 1982
Complement activation and blood levels of 6-oxo-prostaglandin F1alpha during endotoxin-induced hypotension in rabbits.Archives internationales de pharmacodynamie et de therapie, , Volume: 249, Issue:2, 1981
Blood levels of 6-oxo-prostaglandin F 1 alpha during endotoxin-induced hypotension in rabbits.European journal of pharmacology, , Apr-11, Volume: 63, Issue:1, 1980
The effects of drugs on the arachidonate cascade in experimentally burned rabbits.The Journal of burn care & rehabilitation, , Volume: 10, Issue:4
Primary thrombocythaemia in childhood: symptomatic episodes and their relationship to thromboxane A2, 6-keto-PGE1 and 12-hydroxy-eicosatetraenoic acid production: a case report.Prostaglandins, leukotrienes, and medicine, , Volume: 26, Issue:3, 1987
Normal vascular prostacyclin generation in patients with chronic myeloproliferative disorders.Thrombosis research, , Jul-01, Volume: 39, Issue:1, 1985
Modification of inflammatory response to aspiration with ibuprofen.The American journal of physiology, , Volume: 243, Issue:6, 1982
Intermittent pneumatic compression in chronic venous insufficiency favorably affects fibrinolytic potential and platelet activation.Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, , Volume: 7, Issue:4, 1996
Effect of policosanol on experimental thrombosis models.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 50, Issue:5, 1994
Platelet function and fibrinolytic activity in cervical spinal cord injured patients.Thrombosis research, , Feb-01, Volume: 65, Issue:3, 1992
The changes in prostaglandins after segmental pancreatic transplantation.Transplantation proceedings, , Volume: 23, Issue:1 Pt 2, 1991
Elevated levels of 6-keto-prostaglandin-F1a from a lower extremity during external pneumatic compression.Surgery, gynecology & obstetrics, , Volume: 166, Issue:4, 1988
Thromboxane and prostacyclin formation in patients with deep vein thrombosis.Thrombosis research, , Feb-15, Volume: 45, Issue:4, 1987
Study on the antithrombotic effect and physiological mechanism of okanin.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, , Volume: 153, 2022
Panax Notoginseng Saponins Combined with Dual Antiplatelet Drugs Potentiates Anti-Thrombotic Effect with Alleviated Gastric Injury in A Carotid Artery Thrombosis Rat Model.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, , Volume: 31, Issue:8, 2022
[Anti-platelet aggregation and anti-thrombotic mechanism of Trichosanthis Fructus combined with aspirin based on network pharmacology].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 44, Issue:8, 2019
Vascular Nitric Oxide-Superoxide Balance and Thrombus Formation after Acute Exercise.Medicine and science in sports and exercise, , Volume: 50, Issue:7, 2018
Antithrombotic effect and mechanism of Rubus spp. Blackberry.Food & function, , May-24, Volume: 8, Issue:5, 2017
Antithrombotic Effect and Mechanism of Radix Paeoniae Rubra.BioMed research international, , Volume: 2017, 2017
Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB2/6-keto-PGF1α and blood biochemistry in rat model.BMC veterinary research, , Jun-14, Volume: 12, Issue:1, 2016
The antithrombotic effect of RSNK in blood-stasis model rats.Journal of ethnopharmacology, , Sep-15, Volume: 173, 2015
Effect of Ocimum basilicum L. on cyclo-oxygenase isoforms and prostaglandins involved in thrombosis.Journal of ethnopharmacology, , Feb-27, Volume: 152, Issue:1, 2014
Inhibitory effects of Qushuanling Capsule () on thrombus formation and platelet aggregation in rats.Chinese journal of integrative medicine, , Volume: 19, Issue:2, 2013
Pravastatin inhibits plaque rupture and subsequent thrombus formation in atherosclerotic rabbits with hyperlipidemia.Chemical & pharmaceutical bulletin, , Volume: 61, Issue:2, 2013
[The study of relationship between platelet function and thrombus in patients with essential thrombocythaemia].Zhonghua yi xue za zhi, , Jan-26, Volume: 90, Issue:4, 2010
Prothrombotic effects of diclofenac on arteriolar platelet activation and thrombosis in vivo.Journal of thrombosis and haemostasis : JTH, , Volume: 7, Issue:10, 2009
[Development of virulent heat-evil-induced thrombosis animal model].Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 33, Issue:18, 2008
Experimental arterial thrombosis regulated by androgen and its receptor via modulation of platelet activation.Thrombosis research, , Volume: 121, Issue:1, 2007
[Relations of platelet phospholipid fatty acids to thrombotic risk factors in middle-aged and geriatric patients with hyperlipidemia].Zhonghua yi xue za zhi, , Jan-09, Volume: 87, Issue:2, 2007
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.World journal of gastroenterology, , Oct-14, Volume: 13, Issue:38, 2007
Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites.Journal of the American College of Nutrition, , Volume: 26, Issue:5, 2007
N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, , Volume: 58, Issue:3, 2007
In vivo endothelial interaction between ACE and COX inhibitors.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 72, Issue:2, 2005
[Effect of phenolic alkaloids of Menispermum dauricum on thrombosis and platelet aggregation].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 40, Issue:10, 2005
Synergistic effect of D-003 and aspirin on experimental thrombosis models.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 68, Issue:5, 2003
Diet rich in saturated fat decreases the ratio of thromboxane/prostacyclin in healthy men.Biomedical and environmental sciences : BES, , Volume: 16, Issue:4, 2003
Role for thromboxane A2 from glomerular thrombi in nephropathy with type 2 diabetic rats.Life sciences, , May-02, Volume: 72, Issue:24, 2003
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Anti-platelet and anti-thrombotic effects of triacetylshikimic acid in rats.Journal of cardiovascular pharmacology, , Volume: 39, Issue:2, 2002
Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol.Thrombosis research, , Nov-15, Volume: 100, Issue:4, 2000
Platelet-vessel wall interactions with third-generation oral contraceptives: no evidence of detrimental effects.Thrombosis and haemostasis, , Volume: 82, Issue:3, 1999
Left atrial endocardium and prostacyclin.Prostaglandins & other lipid mediators, , Volume: 57, Issue:2-3, 1999
Effect of oral contraceptives containing 20 and 35 micrograms ethinyl estradiol on urinary prostacyclin and thromboxane metabolite levels in smokers and nonsmokers.Contraception, , Volume: 59, Issue:1, 1999
Influence of cadmium intoxication on thromboresistance of vascular endothelium in rabbits.Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, , Volume: 49, Issue:1, 1998
Effects of copper-aspirin complex on platelet aggregation and thrombosis in rabbits and mice.The Journal of pharmacy and pharmacology, , Volume: 50, Issue:11, 1998
Evaluation of a polyester collagen-coated heparin bonded vascular graft.The Journal of cardiovascular surgery, , Volume: 38, Issue:1, 1997
PGE1-induced arterial thromboresistance is a vascular property as identified by cross-perfusion technique.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:4, 1997
The effect of thrombus on the vascular endothelium of arterialized vein grafts.American journal of surgery, , Volume: 172, Issue:2, 1996
Prostacyclin and thromboxane A2 synthesis are increased in acute lower limb ischaemia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 55, Issue:6, 1996
Experimental study on microthrombi and myocardial injuries.Microvascular research, , Volume: 51, Issue:1, 1996
Morphological and hemostatic changes in rats with abdominal arterial prosthesis.Thrombosis research, , Apr-01, Volume: 82, Issue:1, 1996
Experimental studies on preventive effects of API0134 on vessel reocclusion after thrombolysis.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, , Volume: 15, Issue:2, 1995
[Effects of neferine and its combination with taurine on platelet aggregation and experimental thrombosis in rats].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 30, Issue:7, 1995
Procoagulant and prothrombotic responses of human endothelium to indomethacin and endotoxin in vitro. Relevance to non-steroidal anti-inflammatory drug enteropathy.Scandinavian journal of gastroenterology, , Volume: 30, Issue:1, 1995
[Research on plasma TXA2, PGI2 levels, blood stasis syndrome and promoting blood circulation].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:11, 1995
Vitamin E deficiency increases serum thromboxane A2, platelet arachidonate and lipid peroxidation in male Sprague-Dawley rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:1, 1994
Effect of policosanol on experimental thrombosis models.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 50, Issue:5, 1994
Thromboxane and prostacyclin synthesis in experimental pancreas transplantation. Changes in parenchymal and vascular prostanoids.Transplantation, , Volume: 56, Issue:6, 1993
A new bioactive molecule for improving vascular graft patency: exploratory trials in dogs.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 15, Issue:4, 1992
Effect of preservation on blood flow and production of prostacyclin and thromboxane A2 in canine segmental pancreatic autografts.Transplantation proceedings, , Volume: 23, Issue:1 Pt 2, 1991
The changes in prostaglandins after segmental pancreatic transplantation.Transplantation proceedings, , Volume: 23, Issue:1 Pt 2, 1991
[Effect of rhyncophylline on platelet aggregation and experimental thrombosis].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 26, Issue:4, 1991
Rebound elevation in urinary thromboxane B2 and 6-keto-PGF1 alpha excretion after aspirin withdrawal.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21A, 1991
Haemostatic factors associated with vascular thrombosis in patients with systemic lupus erythematosus and the lupus anticoagulant.Annals of the rheumatic diseases, , Volume: 50, Issue:8, 1991
Changes of 6-keto PGF1 alpha concentration in plasma and vessel wall and TxB2 in plasma of whole-body irradiated rats in the early stage of irradiation.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 41, Issue:1, 1990
[Changes in plasma TXB2 and 6-keto-PGF1 alpha and left atrial thrombosis in mitral stenosis].Zhonghua xin xue guan bing za zhi, , Volume: 18, Issue:2, 1990
[Prostacyclin and metabolite assay and the clinical significance].Nihon rinsho. Japanese journal of clinical medicine, , Volume: 48 Suppl, 1990
[Inhibitory effects of new-breviscapine on thrombosis in vivo].Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 9, Issue:1, 1989
Interleukin 1 enhances arterial thrombogenicity in vitro.Thrombosis research, , Nov-15, Volume: 56, Issue:4, 1989
Arachidonic acid metabolites produced by platelet-depleted human blood monocytes: a possible role in thrombogenesis.American journal of hematology, , Volume: 31, Issue:3, 1989
Seeding with endothelial cells derived from the microvessels of the omentum and from the jugular vein: a comparative study.Journal of vascular surgery, , Volume: 7, Issue:5, 1988
Fate of polyester arterial prostheses implanted as thoraco-abdominal by-passes in dogs: haematology, pathology, and biochemistry.Clinical and investigative medicine. Medecine clinique et experimentale, , Volume: 11, Issue:6, 1988
In vivo production of thromboxane and prostacyclin in patients following total hip arthroplasty.Scandinavian journal of clinical and laboratory investigation, , Volume: 48, Issue:3, 1988
Inhibition of prostacyclin and thromboxane A2 generation by low-dose aspirin at the site of plug formation in man in vivo.Circulation, , Volume: 75, Issue:5, 1987
Evaluation of platelet function in pregnancy. Comparative studies in non-smokers and smokers.Thrombosis research, , Apr-15, Volume: 46, Issue:2, 1987
Prostacyclin in systemic lupus and anticardiolipin syndrome.Annals of the rheumatic diseases, , Volume: 46, Issue:5, 1987
Low dose aspirin does not prevent fibrinolytic response to venous occlusion.Biochemical pharmacology, , Sep-15, Volume: 35, Issue:18, 1986
Dazoxiben, UK 38,485 and aspirin: duration of effect for preventing thrombotic sudden death in rabbits.Thrombosis research, , Jul-15, Volume: 43, Issue:2, 1986
The effect of inhibition of thromboxane synthesis in experimental thrombosis and hemostasis.Thrombosis research, , Feb-01, Volume: 37, Issue:3, 1985
Potentiation of the inhibitory effect of a thromboxane A2 antagonist (L-640,035) on arterial thrombosis formation in rabbit by the angiotensin converting enzyme inhibitor enalapril.European journal of pharmacology, , Apr-16, Volume: 110, Issue:3, 1985
[Pathogenetic importance of prostacyclin in atherosclerosis].Terapevticheskii arkhiv, , Volume: 57, Issue:9, 1985
Platelet survival and function in rats with enhanced thrombotic tendency.Thrombosis and haemostasis, , Dec-17, Volume: 54, Issue:4, 1985
Thromboxane production in umbilical vein grafts.Thrombosis research, , Feb-01, Volume: 33, Issue:3, 1984
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Acute arterial thrombosis in rabbits: reduced platelet accumulation after treatment with dazoxiben hydrochloride (UK 37,248-01).British journal of clinical pharmacology, , Volume: 15 Suppl 1, 1983
Sensitivity of rabbit platelet and aortic cyclooxygenase to inhibition by aspirin.Prostaglandins, leukotrienes, and medicine, , Volume: 12, Issue:3, 1983
The antithrombotic effect of aspirin and dipyridamole in relation to prostaglandin synthesis.Thrombosis research, , May-15, Volume: 30, Issue:4, 1983
The antithrombotic nature of vascular prosthetic pseudointima.Surgery, , Volume: 91, Issue:1, 1982
Effect of aspirin and salicylate on platelet-vessel wall interactions in rabbits.Arteriosclerosis (Dallas, Tex.), , Volume: 4, Issue:4
The effect of consuming meat enriched in walnut paste on platelet aggregation and thrombogenesis varies in volunteers with different apolipoprotein A4 genotype.Nutricion hospitalaria, , Volume: 25, Issue:5
Celecoxib inhibits ureteral contractility and prostanoid release.Urology, , Volume: 65, Issue:1, 2005
Ureteral obstruction reverses glomerular proliferation in immune complex glomerulonephritis.The Journal of laboratory and clinical medicine, , Volume: 133, Issue:3, 1999
Ureteral obstruction enhances eicosanoid production in cortical and medullary tubules of rat kidneys.Kidney & blood pressure research, , Volume: 20, Issue:6, 1997
Dietary protein restriction in isolated glomeruli from rats with bilateral ureteral obstruction.Kidney international, , Volume: 46, Issue:1, 1994
Increases in glomerular eicosanoid production in rats with bilateral ureteral obstruction are mediated by enhanced enzyme activities of both the cyclooxygenase and 5-lipoxygenase pathways.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 203, Issue:3, 1993
Mechanism of enhanced eicosanoid production by isolated glomeruli from rats with bilateral ureteral obstruction.The American journal of physiology, , Volume: 261, Issue:2 Pt 2, 1991
Stimulation of renin release by PGE2 and PGI2 infusion in the dog: enhancing effect of ureteral occlusion or administration of ethacrynic acid.Acta physiologica Scandinavica, , Volume: 138, Issue:2, 1990
Renal excretion of prostanoids and cyclic AMP in chronic partial ureteral obstruction of the rabbit.The Journal of urology, , Volume: 141, Issue:2, 1989
Prostaglandins in vascular tone in experimental obstructive nephropathy.Kidney international, , Volume: 19, Issue:6, 1981
Abnormal uterus with polycysts, accumulation of uterine prostaglandins, and reduced fertility in mice heterozygous for acyl-CoA synthetase 4 deficiency.Biochemical and biophysical research communications, , Jun-22, Volume: 284, Issue:4, 2001
Intrauterine infection and the effects of inflammatory mediators on prostaglandin production by myometrial cells from pregnant women.American journal of obstetrics and gynecology, , Volume: 174, Issue:2, 1996
Eicosanoids production in endometriosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 45, Issue:4, 1992
Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma.Cancer research, , Aug-15, Volume: 51, Issue:16, 1991
Prostaglandin and leukotriene concentration of the peritoneal fluid of endometriosis and other gynecologic disorders in the secretory phase.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 39, Issue:1, 1990
Prostacyclin and thromboxane synthesis by endometrial cancer and leiomyomas.Prostaglandins, , Volume: 39, Issue:3, 1990
Prostaglandin production by human myometrium, uterine cervix and leiomyoma.Prostaglandins, leukotrienes, and medicine, , Volume: 29, Issue:1, 1987
Plasma prostaglandin levels in patients with gynecologic malignancies and its fluctuations during chemotherapeutically-induced gastrointestinal toxicity.Japanese journal of clinical oncology, , Volume: 17, Issue:3, 1987
Leiomyomas release prostaglandins.Prostaglandins, leukotrienes, and medicine, , Volume: 18, Issue:1, 1985
Peritoneal fluid 6-keto prostaglandin F1 alpha levels in women with endometriosis.American journal of obstetrics and gynecology, , Aug-01, Volume: 152, Issue:7 Pt 1, 1985
Thromboxane A2 and prostacyclin levels in molar pregnancy.British journal of obstetrics and gynaecology, , Volume: 91, Issue:9, 1984
Cyclic nucleotides and production of prostanoids in human varicose veins.Journal of vascular surgery, , Volume: 30, Issue:5, 1999
[Correlation between serotonin and prostaglandins in peritoneal fluid collected from patients with pelvic congestion].Zhonghua fu chan ke za zhi, , Volume: 28, Issue:6, 1993
Increased prostacyclin and thromboxane A2 formation in human varicose veins.The Journal of surgical research, , Volume: 49, Issue:3, 1990
Differential salicylate-aspirin interaction on vascular prostacyclin and platelet thromboxane synthesis in patients undergoing saphenectomy.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 180, Issue:3, 1985
8-Epi-PGF2alpha and 6-oxo-PGF1alpha in human (varicose) veins: influence of age, sex, and risk factors.Angiology, , Volume: 54, Issue:3
Lipid peroxidation, prostacyclin and thromboxane A2 in pigs depleted of vitamin E and selenium and supplemented with linseed oil.The British journal of nutrition, , Volume: 74, Issue:3, 1995
Vitamin E deficiency increases serum thromboxane A2, platelet arachidonate and lipid peroxidation in male Sprague-Dawley rats.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:1, 1994
Effects of vitamin E on prostacyclin release and lipid composition of the ischemic rat heart.Archives of biochemistry and biophysics, , Volume: 277, Issue:2, 1990
Prostacyclin in pregnancy.European journal of obstetrics, gynecology, and reproductive biology, , Volume: 18, Issue:5-6, 1984
Unbalanced plasma control of TxA2 and PGI2 synthesis in vitamin E-deficient rats.The American journal of physiology, , Volume: 245, Issue:5 Pt 1, 1983
Oxidant- and lipid-induced pulmonary vasoconstriction mediated by arachidonic acid metabolites.Journal of applied physiology: respiratory, environmental and exercise physiology, , Volume: 55, Issue:3, 1983
Differential effects of dietary vitamin E and antioxidants on eicosanoid synthesis in young rabbits.The Journal of nutrition, , Volume: 113, Issue:4, 1983
Decreased prostacyclin synthesis in vitamin E-deficient rabbit aorta.The American journal of clinical nutrition, , Volume: 34, Issue:11, 1981
Effect of ionizing radiation on prostaglandins and gastric secretion in rhesus monkeys.Radiation research, , Volume: 110, Issue:2, 1987
Plasma prostaglandin levels in patients with gynecologic malignancies and its fluctuations during chemotherapeutically-induced gastrointestinal toxicity.Japanese journal of clinical oncology, , Volume: 17, Issue:3, 1987
Plasma 6-keto-prostaglandin F1 alpha in disorders involving hypokalemia.Prostaglandins, leukotrienes, and medicine, , Volume: 9, Issue:5, 1982
Early inflammatory response correlates with the severity of injury.Critical care medicine, , Volume: 24, Issue:7, 1996
Time course of trauma induced alterations of plasma prostanoid levels in intensive care patients.Progress in clinical and biological research, , Volume: 301, 1989
Measurement of 6-keto-PGF1 alpha and thromboxane B2 levels in critically ill surgical patients.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 33, Issue:2, 1988
Thromboxane and prostacyclin release in adult respiratory distress syndrome.Intensive care medicine, , Volume: 13, Issue:3, 1987
The effect of nifedipine, nimodipine and nisoldipine on agonist- and trauma-stimulated vascular prostacyclin synthesis in vitro.Naunyn-Schmiedeberg's archives of pharmacology, , Volume: 332, Issue:1, 1986
Biochemical pathways of acute lung injury.Bulletin europeen de physiopathologie respiratoire, , Volume: 21, Issue:3
Therapeutic effects of flurbiprofen axetil on mesenteric traction syndrome: randomized clinical trial.BMC surgery, , Aug-11, Volume: 17, Issue:1, 2017
Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice.Biochemical and biophysical research communications, , Jul-18, Volume: 372, Issue:1, 2008
Selective thromboxane A2 synthase inhibition by OKY-046 prevents cardiopulmonary dysfunction after ovine smoke inhalation injury.Anesthesiology, , Volume: 102, Issue:5, 2005
Thromboxane receptor blockade with BM 13,177 following toxic airway damage by smoke inhalation in sheep.European journal of pharmacology, , Jun-01, Volume: 248, Issue:1, 1993
Early alterations of lung injury following acute smoke exposure and 21-aminosteroid treatment.Toxicologic pathology, , Volume: 27, Issue:3
Cyclooxygenase-2-Derived Prostaglandins Mediate Cerebral Microcirculation in a Juvenile Ischemic Rat Model.Stroke, , Volume: 47, Issue:12, 2016
[Effects of paeoniflorin on cerebral blood flow and the balance of PGI2/TXA2 of rats with focal cerebral ischemia-reperfusion injury].Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 49, Issue:1, 2014
Chemical composition of hepatic lipids mediates reperfusion injury of the macrosteatotic mouse liver through thromboxane A(2).Journal of hepatology, , Volume: 55, Issue:6, 2011
Injectable caltrop fruit saponin protects against ischemia-reperfusion injury in rat brain.The American journal of Chinese medicine, , Volume: 39, Issue:2, 2011
Activation of sensory neurons reduces ischemia/reperfusion-induced acute renal injury in rats.Anesthesiology, , Volume: 110, Issue:2, 2009
Atrial natriuretic peptide reduces ischemia/reperfusion-induced spinal cord injury in rats by enhancing sensory neuron activation.The Journal of pharmacology and experimental therapeutics, , Volume: 322, Issue:2, 2007
Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats.Critical care medicine, , Volume: 34, Issue:7, 2006
[Protective effect of ligustrazine and propofol on peri-operational liver ischemia-reperfusion injury].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 26, Issue:3, 2006
Contribution of capsaicin-sensitive sensory neurons to antithrombin-induced reduction of ischemia/reperfusion-induced liver injury in rats.Thrombosis and haemostasis, , Volume: 93, Issue:1, 2005
Antithrombin III pretreatment reduces neutrophil recruitment into the lung and skeletal muscle tissues in the rat model of bilateral lower limb ischemia and reperfusion: a pilot study.Acta anaesthesiologica Scandinavica, , Volume: 49, Issue:8, 2005
Bradykinin B2 receptor antagonist FR173657 ameliorates small bowel ischemia-reperfusion injury in dogs.Digestive diseases and sciences, , Volume: 50, Issue:1, 2005
Neutrophil elastase contributes to the development of ischemia-reperfusion-induced liver injury by decreasing endothelial production of prostacyclin in rats.American journal of physiology. Gastrointestinal and liver physiology, , Volume: 287, Issue:6, 2004
Antithrombin reduces ischemia/reperfusion-induced liver injury in rats by activation of cyclooxygenase-1.Thrombosis and haemostasis, , Volume: 92, Issue:3, 2004
Antithrombin reduces the ischemia/reperfusion-induced spinal cord injury in rats by attenuating inflammatory responses.Thrombosis and haemostasis, , Volume: 91, Issue:1, 2004
Antithrombin reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation through promotion of prostacyclin production.Blood, , Apr-15, Volume: 101, Issue:8, 2003
Ischemia/reperfusion-induced increase in the hepatic level of prostacyclin is mainly mediated by activation of capsaicin-sensitive sensory neurons in rats.The Journal of laboratory and clinical medicine, , Volume: 139, Issue:4, 2002
Antithrombin III prevents early pulmonary dysfunction after lung transplantation in the dog.Circulation, , Dec-11, Volume: 104, Issue:24, 2001
Effects of FK3311 on pulmonary ischemia-reperfusion injury in a canine model.The Journal of surgical research, , Volume: 95, Issue:2, 2001
Effects of diclofenac in the rat tail ischaemia--reperfusion injury model of acute hyperalgesia.Pain, , Volume: 89, Issue:2-3, 2001
The effect of cyclooxygenase-2 inhibitor FK3311 on ischemia-reperfusion injury in a canine total hepatic vascular exclusion model.Journal of the American College of Surgeons, , Volume: 192, Issue:1, 2001
The effect of a selective cyclooxygenase-2 inhibitor in extended liver resection with ischemia in dogs.The Journal of surgical research, , Volume: 100, Issue:1, 2001
Intravenous aspirin at reperfusion does not reduce infarct size in the dog with a residual critical stenosis.Journal of cardiovascular pharmacology, , Volume: 34, Issue:4, 1999
Effect of ozagrel on locomotor and motor coordination after transient cerebral ischemia in experimental animal models.Pharmacology, , Volume: 59, Issue:5, 1999
Antithrombin reduces ischemia/reperfusion injury of rat liver by increasing the hepatic level of prostacyclin.Blood, , Jan-01, Volume: 93, Issue:1, 1999
Effects of low-dose Beraprost sodium, a stable prostaglandin I2 analogue, on reperfusion injury to rabbit lungs.American journal of respiratory and critical care medicine, , Volume: 158, Issue:5 Pt 1, 1998
Serial experimental and clinical studies on the pathogenesis of multiple organ dysfunction syndrome (MODS) in severe burns.Burns : journal of the International Society for Burn Injuries, , Volume: 24, Issue:8, 1998
Ischemia/reperfusion injury in the rat colon.Inflammation, , Volume: 21, Issue:2, 1997
Effects of a thromboxane synthetase inhibitor (OKY-046) in an ischemia-reperfusion model of intrauterine growth retardation in Sprague-Dawley rats.Biology of the neonate, , Volume: 72, Issue:3, 1997
Differential effect of nitric oxide inhibition as a function of preservation period in pancreas transplantation.Digestive diseases and sciences, , Volume: 42, Issue:5, 1997
Effects of dl-3-n-butylphthalide on production of TXB2 and 6-keto-PGF1 alpha in rat brain during focal cerebral ischemia and reperfusion.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 18, Issue:6, 1997
Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine.Pharmacology, , Volume: 53, Issue:2, 1996
Protective effects of antithrombin III supplementation on warm ischemia and reperfusion injury in rat liver.World journal of surgery, , Volume: 20, Issue:8, 1996
Effects of platelet-activating factor antagonist E5880 on intrahepatic and systemic metabolic responses to transient hepatic inflow occlusion and reperfusion in the rabbit.World journal of surgery, , Volume: 20, Issue:8, 1996
Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model.Transplantation, , May-27, Volume: 61, Issue:10, 1996
Leukocyte and platelet depletion protects the liver from damage induced by cholestasis and ischemia-reperfusion in the dog.Scandinavian journal of gastroenterology, , Volume: 31, Issue:2, 1996
Effect of acetylsalicylic acid on metabolism and contractility in the ischemic reperfused heart.Japanese circulation journal, , Volume: 60, Issue:12, 1996
Thromboxane A2 in preservation-reperfusion injury: the effect of thromboxane A2 synthetase inhibitor.The Journal of surgical research, , Volume: 62, Issue:2, 1996
[Comparison of effect of Astragalus membranaceus and huoxuefang on thromboxane, prostacyclin and adenosine cyclic monophosphate in cerebral reperfusion injury in rabbits].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 15, Issue:3, 1995
Role of xanthine oxidase and eicosanoids in development of pancreatic ischemia-reperfusion injury.Inflammation, , Volume: 19, Issue:4, 1995
Renal protective effect of liposomed superoxide dismutase in an experimental warm ischemia model.Transplant international : official journal of the European Society for Organ Transplantation, , Volume: 7 Suppl 1, 1994
Prostaglandin E1 protects dog pancreas from ischemia-reperfusion injury.Pancreas, , Volume: 9, Issue:3, 1994
Role of the bronchial circulation in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 76, Issue:1, 1994
Protective effect of the thromboxane A2 receptor antagonist ONO 3708 on ischemia-reperfusion injury in the dog liver.Surgery, , Volume: 116, Issue:5, 1994
The protective effect of thromboxane A2 synthetase inhibitor against ischemic liver injury.Surgery today, , Volume: 24, Issue:5, 1994
Effects of leukocyte and platelet depletion on ischemia--reperfusion injury to dog pancreas.Gastroenterology, , Volume: 107, Issue:4, 1994
Thromboxane contributes to pulmonary hypertension in ischemia-reperfusion lung injury.Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 74, Issue:1, 1993
Effect of a novel thromboxane A2 receptor antagonist, S-1452, on postischemic brain injury in rats.Stroke, , Volume: 24, Issue:12, 1993
[The effect of hyperbaric oxygenation on prostaglandin I2 and thromboxane A2 during reperfusion for experimental cerebral ischemia in rabbits].Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 25, Issue:1, 1992
Pancreas prostanoid production in ischemia and reperfusion.Prostaglandins, , Volume: 43, Issue:5, 1992
Protective effect of indomethacin in the development of the postreperfusion syndrome during liver transplantation in pigs.Transplantation proceedings, , Volume: 23, Issue:4, 1991
Inhibition of cyclooxygenase metabolite production attenuates ischemia-reperfusion lung injury.The American review of respiratory disease, , Volume: 143, Issue:3, 1991
Interactions between platelet-activating factor and prostanoids during mesenteric ischemia-reperfusion-induced shock in the anesthetized dog.Circulatory shock, , Volume: 35, Issue:1, 1991
The influence of arachidonic acid metabolites on leukocyte activation and skeletal muscle injury after ischemia and reperfusion.Journal of vascular surgery, , Volume: 14, Issue:4, 1991
Altered levels of tissue and urinary prostacyclin in rats subjected to pancreas transplantation.Prostaglandins, , Volume: 41, Issue:6, 1991
Anti-lipid peroxidation and protection of ginsenosides against cerebral ischemia-reperfusion injuries in rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 11, Issue:2, 1990
Hydrogen peroxide-induced alterations in prostaglandin secretion in the rat colon in vitro.Inflammation, , Volume: 14, Issue:6, 1990
Limb ischemia-induced increase in permeability is mediated by leukocytes and leukotrienes.Annals of surgery, , Volume: 208, Issue:6, 1988
Inhibition of thromboxane A2 synthesis by OKY-046 attenuates ischemia and reperfusion injury of the liver.Transplantation proceedings, , Volume: 31, Issue:1-2
The effects of a selective cyclooxygenase-2 inhibitor on small bowel ischemia-reperfusion injury.Hepato-gastroenterology, , Volume: 50, Issue:54
Effect of platelet-activating factor antagonist L-691,880 on low-flow ischemia-reperfusion injury of the large colon in horses.Veterinary surgery : VS, , Volume: 27, Issue:1
Suppression of cytokine production by thromboxane A2 inhibitor in liver ischemia.Hepato-gastroenterology, , Volume: 45, Issue:23
[Effects of Electroacupuncture Stimulation of "Neiguan" (PC 6) at Different Frequencies on Plasma Vasoactive Substance Levels in Myocardial Ischemic Reperfusion Rats].Zhen ci yan jiu = Acupuncture research, , Volume: 40, Issue:5, 2015
Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect.Arteriosclerosis, thrombosis, and vascular biology, , Volume: 34, Issue:9, 2014
[Effect of precondition with GBE50 and Salviae miltionrrhizae on cycloxygenase-2 and its downstream effectors contents in ischemia/reperfusion myocardium].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 30, Issue:10, 2010
Anti-ischemic activity and endothelium-dependent vasorelaxant effect of hydrolysable tannins from the leaves of Rhus coriaria (Sumac) in isolated rabbit heart and thoracic aorta.Planta medica, , Volume: 75, Issue:14, 2009
Intravenous glutamine enhances COX-2 activity giving cardioprotection.The Journal of surgical research, , Volume: 152, Issue:1, 2009
Postconditioning and intermittent bradykinin induced cardioprotection require cyclooxygenase activation and prostacyclin release during reperfusion.Basic research in cardiology, , Volume: 103, Issue:4, 2008
Pretreatment with high-dose statin, but not low-dose statin, ezetimibe, or the combination of low-dose statin and ezetimibe, limits infarct size in the rat.Journal of cardiovascular pharmacology and therapeutics, , Volume: 13, Issue:1, 2008
Pioglitazone protects the myocardium against ischemia-reperfusion injury in eNOS and iNOS knockout mice.American journal of physiology. Heart and circulatory physiology, , Volume: 295, Issue:6, 2008
Aspirin before reperfusion blunts the infarct size limiting effect of atorvastatin.American journal of physiology. Heart and circulatory physiology, , Volume: 292, Issue:6, 2007
The effect of Ginkgo biloba in isolated ischemic/reperfused rat heart: a link between vitamin E preservation and prostaglandin biosynthesis.Journal of cardiovascular pharmacology, , Volume: 44, Issue:3, 2004
Procyanidins from Vitis vinifera seeds display cardioprotection in an experimental model of ischemia-reperfusion damage.Drugs under experimental and clinical research, , Volume: 29, Issue:5-6, 2003
Influence of antithrombin on ischemia/reperfusion injury in the isolated blood-free perfused rat heart.Thrombosis research, , Nov-25, Volume: 108, Issue:4, 2002
[Effects of Salvia miltiorrhiza compound injection on serum endothelin, prostaglandin I2/thromboxane A2 ratio alteration following myocardial ischemia-reperfusion in patients undergoing intracardiac surgery].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 20, Issue:12, 2000
Myocardial protection by the nitroderivative of aspirin, NCX 4016: in vitro and in vivo experiments in the rabbit.Italian heart journal : official journal of the Italian Federation of Cardiology, , Volume: 1, Issue:2, 2000
Endocrine, metabolic and cardioprotective effects of hexarelin in obese Zucker rats.The Journal of endocrinology, , Volume: 166, Issue:3, 2000
Participation of prostaglandin E2 in the endothelial protective effect of ischaemic preconditioning in isolated rat heart.Cardiovascular research, , Jan-14, Volume: 45, Issue:2, 2000
Growth hormone-independent cardioprotective effects of hexarelin in the rat.Endocrinology, , Volume: 140, Issue:9, 1999
Effects of depletion of leukocytes and platelets on cardiac dysfunction after cardiopulmonary bypass.The Annals of thoracic surgery, , Volume: 65, Issue:1, 1998
Protectant activity of hexarelin or growth hormone against postischemic ventricular dysfunction in hearts from aged rats.Journal of cardiovascular pharmacology, , Volume: 32, Issue:2, 1998
Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:2, 1997
Cardiac ischemia and impairment of vascular endothelium function in hearts from growth hormone-deficient rats: protection by hexarelin.European journal of pharmacology, , Sep-10, Volume: 334, Issue:2-3, 1997
Effects of the new class I antiarrhythmic agent Ro 22-9194, (2R)-2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide D-tartrate, on ischemia- and reperfusion-induced arrhythmias in dogs: involvement of thromboxane A2 synthase inhibitory actThe Journal of pharmacology and experimental therapeutics, , Volume: 279, Issue:2, 1996
Protective effects of ITF 296 in the isolated rabbit heart subjected to global ischemia.Journal of cardiovascular pharmacology, , Volume: 26 Suppl 4, 1995
[Reduction of incidence of ischemia-reperfusion induced ventricular fibrillation by captopril].Sheng li xue bao : [Acta physiologica Sinica], , Volume: 47, Issue:6, 1995
Prostanoid production in hypoxic rat isolated atria: influence of acute diabetes.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 51, Issue:4, 1994
Effect of captopril cardioplegia on renin-angiotensin system, prostaglandins, free radicals and electrolytes in the isolated hypothermic ischemic and reperfusion rabbit hearts.Chinese medical journal, , Volume: 106, Issue:12, 1993
Effects of quercetin on platelet and reperfusion-induced arrhythmias in rats.Zhongguo yao li xue bao = Acta pharmacologica Sinica, , Volume: 14, Issue:6, 1993
[Effect of ligustrazine on isolated myocardial ischemic reperfusion injury in rats].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:4, 1993
Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury.The Journal of pharmacology and experimental therapeutics, , Volume: 264, Issue:1, 1993
Protective effect of the new antiplatelet agent 2-methyl-3-(1,4,5,6-tetrahydronicotinoyl)pyrazolo[1,5-a]pyridine on myocardial damage due to coronary occlusion and reperfusion in rabbit.Arzneimittel-Forschung, , Volume: 42, Issue:1, 1992
Effects of early angiotensin-converting enzyme inhibition in a pig model of myocardial ischemia and reperfusion.Journal of cardiovascular pharmacology, , Volume: 19, Issue:3, 1992
Cicletanine and reperfusion injury: is there any correlation between arrhythmias, 6-keto-PGF1 alpha, thromboxane B2, and myocardial ion shifts (Na+, K+, Ca2+, and Mg2+) induced by ischemia/reperfusion in isolated rat heart.Journal of cardiovascular pharmacology, , Volume: 17, Issue:4, 1991
Captopril, an ACE inhibitor, for optimizing reperfusion after acute myocardial infarction.The Annals of thoracic surgery, , Volume: 52, Issue:4, 1991
Effect of cicletanine on reperfusion-induced arrhythmias and its relation to 6-keto-PGF1 alpha and thromboxane B2 release.Canadian journal of physiology and pharmacology, , Volume: 69, Issue:4, 1991
Opposite effects of PGI2 and PAF generated during acute myocardial ischemia in the perfused rabbit heart.Advances in prostaglandin, thromboxane, and leukotriene research, , Volume: 21B, 1991
Experimental evaluation of myocardial protective effect of prostacyclin analog (OP-41483) as an adjunct to cardioplegic solution.The Journal of thoracic and cardiovascular surgery, , Volume: 101, Issue:5, 1991
Effects of vitamin E on prostacyclin release and lipid composition of the ischemic rat heart.Archives of biochemistry and biophysics, , Volume: 277, Issue:2, 1990
Enhanced prostaglandin production in the ischemic-reperfused myocardium by captopril linked with its free radical scavenging action.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 38, Issue:2, 1989
Ischemia-induced arachidonic acid accumulation and prostanoid release during reperfusion in the isolated rat heart.Progress in clinical and biological research, , Volume: 301, 1989
Role of a nonsteroidal anti-inflammatory agent, ibuprofen, in coronary revascularization after acute myocardial infarction.Basic research in cardiology, , Volume: 85, Issue:1
Myocardial reactive hyperaemia in perfused guinea pig heart.Polish journal of pharmacology, , Volume: 47, Issue:5
Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness.Journal of virology, , Volume: 78, Issue:19, 2004
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.The Journal of nutritional biochemistry, , Volume: 14, Issue:8, 2003
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.The Journal of nutritional biochemistry, , Volume: 14, Issue:11, 2003
Lack of endothelium-derived hyperpolarizing factor (EDHF) up-regulation in endothelial dysfunction in aorta in diabetic rats.Pharmacological reports : PR, , Volume: 59, Issue:4
[Active factors released by endothelial cells in acute leukemia].Zhonghua nei ke za zhi, , Volume: 33, Issue:1, 1994
Hypercoagulable state and hemorrhage in acute leukemias.Chinese medical journal, , Volume: 101, Issue:6, 1988
Urinary 6-keto-PGF1 alpha level in patients with childhood leukemia/lymphoma; a possible indicator of vascular damage.Prostaglandins, leukotrienes, and medicine, , Volume: 28, Issue:2, 1987
Effect of H. pylori infection on the expression of cyclooxygenase-2 in human gastric mucosa.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 68, Issue:1, 2003
Chronic gastritis, prostaglandins and Helicobacter pylori.Zeitschrift fur Gastroenterologie, , Volume: 31, Issue:10, 1993
Structural, functional and circulatory placental changes associated with impaired glucose metabolism.European journal of obstetrics, gynecology, and reproductive biology, , Nov-15, Volume: 105, Issue:2, 2002
Prostanoid production in the umbilicoplacental arterial tree relative to impaired glucose tolerance.Early human development, , Jan-09, Volume: 50, Issue:2, 1998
[Influence of qi-gong on plasma TXB2 and 6-keto-PGF1 alpha in two TCM types of essential hypertension].Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, , Volume: 22, Issue:6, 1997
[Study on relationship of lipid peroxide in coronary heart disease with and without diabetes].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 16, Issue:1, 1996
[Clinical study of qianxining in the treatment of 60 cases of yang hyperactivity due to yin deficiency type of hypertension].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 12, Issue:7, 1992
[Therapeutic changes in nephrotic syndrome treated with yiqi huoxue jiedu decoction and corticosteroid].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 12, Issue:8, 1992
The hemodynamic abnormalities in short-term insulin deficiency: the role of prostaglandin inhibition.Diabetes, , Volume: 45, Issue:5, 1996
Plasma 6-keto-PGF1 alpha, thromboxane B2 and PGE2 during diabetic ketoacidosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 40, Issue:1, 1990
Plasma 6-keto-PGF1 alpha, thromboxane B2 and PGE2 during diabetic ketoacidosis.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 41, Issue:4, 1990
Prostacyclin and pathogenesis of hemodynamic abnormalities of diabetic ketoacidosis in rats.Diabetes, , Volume: 38, Issue:12, 1989
The effect of streptozotocin-induced diabetes on PGI2 synthesis by the rat bladder.The Journal of urology, , Volume: 135, Issue:6, 1986
Plasma eicosanoid levels in rats with nonketotic diabetes mellitus: effect of severity.Metabolism: clinical and experimental, , Volume: 35, Issue:4, 1986
Experimental diabetes mellitus inhibits prostacyclin synthesis by the rat penis: pathological implications.Diabetologia, , Volume: 28, Issue:6, 1985
Plasma prostaglandin levels and circulating fuel levels in rats with diabetic ketoacidosis: effects of cyclooxygenase inhibitors and of alpha and beta adrenergic blockade.Prostaglandins, , Volume: 28, Issue:3, 1984
Plasma prostaglandin levels in rats with diabetes mellitus and diabetic ketoacidosis.Diabetes, , Volume: 31, Issue:11, 1982
Prostacyclin synthase gene transfer accelerates reendothelialization and inhibits neointimal formation in rat carotid arteries after balloon injury.Arteriosclerosis, thrombosis, and vascular biology, , Volume: 19, Issue:3, 1999
Gene transfer of human prostacyclin synthase prevents neointimal formation after carotid balloon injury in rats.Stroke, , Volume: 30, Issue:2, 1999
Anti-myocardial ischemia effect of Syringa pinnatifolia Hemsl. by inhibiting expression of cyclooxygenase-1 and -2 in myocardial tissues of mice.Journal of ethnopharmacology, , Jul-01, Volume: 187, 2016
[Effect of precondition with GBE50 and Salviae miltionrrhizae on cycloxygenase-2 and its downstream effectors contents in ischemia/reperfusion myocardium].Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 30, Issue:10, 2010
Postconditioning and intermittent bradykinin induced cardioprotection require cyclooxygenase activation and prostacyclin release during reperfusion.Basic research in cardiology, , Volume: 103, Issue:4, 2008
Aspirin before reperfusion blunts the infarct size limiting effect of atorvastatin.American journal of physiology. Heart and circulatory physiology, , Volume: 292, Issue:6, 2007
Adenosine cardioprotection study in clinical setting of paroxysmal supraventricular tachycardia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 74, Issue:6, 2006
The effect of Ginkgo biloba in isolated ischemic/reperfused rat heart: a link between vitamin E preservation and prostaglandin biosynthesis.Journal of cardiovascular pharmacology, , Volume: 44, Issue:3, 2004
Effects of nicotine on thromboxane/prostacyclin balance in myocardial ischemia.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 68, Issue:3, 2003
Role of calcitonin gene-related peptide in prostaglandins-mediated ischemic preconditioning in guinea pig hearts.Acta pharmacologica Sinica, , Volume: 22, Issue:1, 2001
Myocardial outflow of prostacyclin in relation to metabolic stress during off-pump coronary artery bypass grafting.The Annals of thoracic surgery, , Volume: 70, Issue:1, 2000
Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits.Proceedings of the National Academy of Sciences of the United States of America, , Aug-29, Volume: 97, Issue:18, 2000
Growth hormone-independent cardioprotective effects of hexarelin in the rat.Endocrinology, , Volume: 140, Issue:9, 1999
Protectant activity of hexarelin or growth hormone against postischemic ventricular dysfunction in hearts from aged rats.Journal of cardiovascular pharmacology, , Volume: 32, Issue:2, 1998
Hexarelin exhibits protective activity against cardiac ischaemia in hearts from growth hormone-deficient rats.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, , Volume: 8 Suppl B, 1998
Cardiac ischemia and impairment of vascular endothelium function in hearts from growth hormone-deficient rats: protection by hexarelin.European journal of pharmacology, , Sep-10, Volume: 334, Issue:2-3, 1997
Cardioprotection by cyclosporine A in experimental ischemia and reperfusion--evidence for a nitric oxide-dependent mechanism mediated by endothelin.Journal of molecular and cellular cardiology, , Volume: 29, Issue:2, 1997
Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:2, 1997
Effect of acetylsalicylic acid on metabolism and contractility in the ischemic reperfused heart.Japanese circulation journal, , Volume: 60, Issue:12, 1996
Ischaemic cardiac hyperaemia: role of nitric oxide and other mediators.Physiological research, , Volume: 45, Issue:4, 1996
Oxygen deprivation and reoxygenation augment prostacyclin synthesis in cultured ventricular myocytes.Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 54, Issue:3, 1996
Effects of the new class I antiarrhythmic agent Ro 22-9194, (2R)-2-amino-N-(2,6-dimethylphenyl)-N-[3-(3-pyridyl)propyl]propionamide D-tartrate, on ischemia- and reperfusion-induced arrhythmias in dogs: involvement of thromboxane A2 synthase inhibitory actThe Journal of pharmacology and experimental therapeutics, , Volume: 279, Issue:2, 1996
[Effects of low dose aspirin on platelet function and prostaglandins metabolism in systemic and coronary circulation in patients with ischemia heart disease].Zhonghua nei ke za zhi, , Volume: 34, Issue:9, 1995
[Effects of selenium and vitamin E on arachidonic acid metabolism in experimental myocardial ischaemia].Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], , Volume: 29, Issue:5, 1995
Protective effects of ITF 296 in the isolated rabbit heart subjected to global ischemia.Journal of cardiovascular pharmacology, , Volume: 26 Suppl 4, 1995
Effects of bepridil on silent myocardial ischemia and eicosanoid metabolism in chronic stable angina pectoris after healing of myocardial infarction.The American journal of cardiology, , Jun-01, Volume: 73, Issue:15, 1994
Release of 6-keto-PGF1 alpha and thromboxane B2 in late appearing cardioprotection induced by the stable PGI analogue: 7-OXO-PGI.Molecular and cellular biochemistry, , Feb-17, Volume: 119, Issue:1-2, 1993
Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury.The Journal of pharmacology and experimental therapeutics, , Volume: 264, Issue:1, 1993
Effect of diltiazem on silent ischemic episodes, plasma bradykinin and prostaglandin metabolism.International journal of cardiology, , Volume: 37, Issue:2, 1992
[The prostacyclin-thromboxane system and platelet hemostasis following aortocoronary bypass with an uncomplicated postoperative course].Anesteziologiia i reanimatologiia, , Issue:5-6
Safety/Toxicity (28)
| Article | Year |
|---|
Attenuation of ciclosporin-induced nephrotoxicity by dietary supplementation of seal oil in Sprague-Dawley rats.
The Journal of pharmacy and pharmacology, , Volume: 57, Issue:11 | 2005 |
Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 71, Issue:5 | 2004 |
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.
The Journal of nutritional biochemistry, , Volume: 14, Issue:11 | 2003 |
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.
The Journal of nutritional biochemistry, , Volume: 14, Issue:8 | 2003 |
Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide?
Kidney & blood pressure research, , Volume: 24, Issue:2 | 2001 |
Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 63, Issue:5 | 2000 |
Prostanoids and free radicals in Cl4C-induced hepatotoxicity in rats: effect of astilbin.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 56, Issue:4 | 1997 |
Stimulation of prostaglandin production by quinolone phototoxicity in Balb/c 3T3 mouse fibroblast cells in vitro.
Fundamental and applied toxicology : official journal of the Society of Toxicology, , Volume: 36, Issue:2 | 1997 |
Comparative cytotoxicity of monocrotaline and its metabolites in cultured pulmonary artery endothelial cells.
Toxicology and applied pharmacology, , Volume: 143, Issue:1 | 1997 |
Dialysis fluid cytotoxicity and inhibition of host defence in cultured human mesothelial cells are neutralized rapidly with incubation in the peritoneum.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, , Volume: 11, Issue:12 | 1996 |
Gastric toxicity and prostaglandin content in rats dosed with two chemically similar, nonsteroidal anti-inflammatory agents.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 202, Issue:2 | 1993 |
Alleviation of experimental cyclosporin A nephrotoxicity by low dose aspirin in the rat.
Biochemical pharmacology, , Dec-03, Volume: 46, Issue:11 | 1993 |
Reduction of cyclosporine-induced nephrotoxicity by cilastatin following clinical heart transplantation.
Transplantation, , Mar-27, Volume: 57, Issue:6 | 1994 |
Alteration of cyclosporine (CsA)-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in Wistar rats.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 50, Issue:1 | 1994 |
[Prevention of toxicity of cyclosporine A on rat pancreatic islet beta-cells by Ligustrazine].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, , Volume: 13, Issue:9 | 1993 |
Prevention of experimental cyclosporine nephrotoxicity by dietary supplementation with LSL 90202, a lysine salt of eicosapentaenoic acid. Role of thromboxane and prostacyclin in renal tissue.
Nephron, , Volume: 67, Issue:1 | 1994 |
Effect of corticosteroid treatment on salicylate ototoxicity.
The Annals of otology, rhinology, and laryngology, , Volume: 103, Issue:11 | 1994 |
Prostanoids and cyclosporin-mediated nephrotoxicity in rats: a critical appraisal.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 52, Issue:1 | 1995 |
Tacrolimus (FK506)-induced nephrotoxicity in spontaneous hypertensive rats.
The Journal of toxicological sciences, , Volume: 19, Issue:4 | 1994 |
Acute cyclosporine A nephrotoxicity in rats: which role for renin-angiotensin system and glomerular prostaglandins?
Clinical nephrology, , Volume: 25 Suppl 1 | 1986 |
Endotoxin protection against pulmonary oxygen toxicity and plasma prostaglandin levels in the rat.
Advances in experimental medicine and biology, , Volume: 215 | 1987 |
Plasma prostaglandin levels in patients with gynecologic malignancies and its fluctuations during chemotherapeutically-induced gastrointestinal toxicity.
Japanese journal of clinical oncology, , Volume: 17, Issue:3 | 1987 |
Selective enhancement of thromboxane in macrophages and kidneys in cyclosporine-induced nephrotoxicity. Dietary protection by fish oil.
Transplantation, , Volume: 45, Issue:1 | 1988 |
Asbestos-induced endothelial cell activation and injury. Demonstration of fiber phagocytosis and oxidant-dependent toxicity.
The American review of respiratory disease, , Volume: 138, Issue:4 | 1988 |
Prostacyclin release and cytotoxicity of peritoneal cells are inversely related in pregnant and non-pregnant mice infected with herpes simplex virus.
American journal of reproductive immunology (New York, N.Y. : 1989), , Volume: 20, Issue:4 | 1989 |
Cellular and eicosanoid composition of bronchoalveolar lavage fluid in endotoxin protection against pulmonary oxygen toxicity.
Critical care medicine, , Volume: 17, Issue:3 | 1989 |
Theoretical mechanism for the gastrointestinal safety of etodolac: selective sparing of cytoprotective prostaglandins.
Clinical rheumatology, , Volume: 8 Suppl 1 | 1989 |
Attenuation of endotoxin-induced cytotoxicity and prostacyclin production in cultured bovine pulmonary artery endothelial cells by phosphodiesterase inhibition.
Experimental lung research, , Volume: 14, Issue:5 | 1988 |
Long-term Use (19)
| Article | Year |
|---|
Altered reactivity to norepinephrine through COX-2 induction by vascular injury in hypercholesterolemic rabbits.
American journal of physiology. Heart and circulatory physiology, , Volume: 297, Issue:5 | 2009 |
Chronic administration of ethyl docosahexaenoate reduces gerbil brain eicosanoid productions following ischemia and reperfusion.
The Journal of nutritional biochemistry, , Volume: 17, Issue:4 | 2006 |
Effects of antioxidants on coronary microvascular spasm induced by epicardial coronary artery endothelial injury in pigs.
Coronary artery disease, , Volume: 15, Issue:1 | 2004 |
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America, , Mar-13, Volume: 98, Issue:6 | 2001 |
Hexarelin exhibits protective activity against cardiac ischaemia in hearts from growth hormone-deficient rats.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, , Volume: 8 Suppl B | 1998 |
Systemic and pulmonary hypertension after abrupt cessation of prostacyclin: role of thromboxane A2.
Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 80, Issue:1 | 1996 |
Hemodynamic and biochemical changes after chronic administration of cilazapril to hypertensive patients.
Cardiology, , Volume: 82, Issue:4 | 1993 |
Pyrazolopyridine derivative acts as a novel cyclooxygenase inhibitor: antiplatelet effect in aged patients with ischemic stroke.
Journal of the American Geriatrics Society, , Volume: 42, Issue:6 | 1994 |
Comparison of the anti-inflammatory activity and gastrointestinal irritancy of nabumetone, ibuprofen, and diclofenac in rats following chronic administration.
European journal of rheumatology and inflammation, , Volume: 14, Issue:2 | 1994 |
Defective synthesis of vasodilator prostaglandins in the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979), , Volume: 6, Issue:2 Pt 2 | |
In vivo production of prostaglandin I2 in Dahl salt-sensitive and salt-resistant rats.
Hypertension (Dallas, Tex. : 1979), , Volume: 5, Issue:5 | |
Effect of cyclosporine administration on renal hemodynamics in conscious rats.
Kidney international, , Volume: 28, Issue:5 | 1985 |
Effects of sulindac on renal and extrarenal eicosanoid synthesis.
Clinical pharmacology and therapeutics, , Volume: 41, Issue:4 | 1987 |
Ethanol administration in the rat decreases prostacyclin production by isolated brain microvessels.
Journal of neurochemistry, , Volume: 46, Issue:5 | 1986 |
In vivo indexes of platelet and vascular function during fish-oil administration in patients with atherosclerosis.
The New England journal of medicine, , Apr-10, Volume: 314, Issue:15 | 1986 |
Effect of high-dose etodolac on renal function.
Clinical pharmacology and therapeutics, , Volume: 42, Issue:3 | 1987 |
Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase.
Circulation, , Volume: 73, Issue:6 | 1986 |
Thromboxane synthesis inhibition and renal allograft function.
Transplantation proceedings, , Volume: 21, Issue:1 Pt 1 | 1989 |
Compared effects of isoxicam and indomethacin on the urinary excretion of prostaglandins in degenerative articular diseases.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 38, Issue:2 | 1989 |
Pharmacokinetics (13)
| Article | Year |
|---|
Pharmacokinetics and pharmacodynamics of terbogrel, a combined thromboxane A2 receptor and synthase inhibitor, in healthy subjects.
British journal of clinical pharmacology, , Volume: 58, Issue:1 | 2004 |
Volume-induced natriuresis in healthy women: renal metabolism of prostacyclin and thromboxane, and physiological role of prostanoids.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 64, Issue:2 | 2001 |
Platelet volume and urinary prostanoid metabolites in non-insulin-dependent diabetes mellitus.
Journal of atherosclerosis and thrombosis, , Volume: 1, Issue:2 | 1994 |
Pharmacokinetic and pharmacodynamic properties of FK070 (KDI-792), a novel thromboxane receptor antagonist/thromboxane synthetase inhibitor, after single and multiple oral administrations to healthy volunteers.
The Journal of pharmacy and pharmacology, , Volume: 48, Issue:4 | 1996 |
Pharmacokinetic and pharmacodynamic profiles of CS-518, a selective, long-lasting thromboxane synthase inhibitor, after single and multiple oral administration to healthy volunteers.
Journal of clinical pharmacology, , Volume: 34, Issue:1 | 1994 |
Angiotensin II metabolic clearance rate and pressor responses in nonpregnant and pregnant women.
American journal of obstetrics and gynecology, , Volume: 171, Issue:3 | 1994 |
Urinary excretion of prostaglandin F2 alpha and 6-keto-prostaglandin F1 alpha during volume expansion in patients with glomerulonephritis.
Acta medica Scandinavica, , Volume: 212, Issue:5 | 1982 |
The sex-related differences in aspirin pharmacokinetics in rabbits and man and its relationship to antiplatelet effects.
Thrombosis research, , Jan-15, Volume: 29, Issue:2 | 1983 |
Single intravenous and oral doses of fenflumizole: pharmacokinetics and effects on prostanoid formation.
Acta pharmacologica et toxicologica, , Volume: 57, Issue:2 | 1985 |
Peritoneal fluid volume, estrogen, progesterone, prostaglandin, and epidermal growth factor concentrations in patients with and without endometriosis.
Obstetrics and gynecology, , Volume: 68, Issue:2 | 1986 |
Influence of renal insufficiency on the pharmacokinetics of cicletanine and its effects on the urinary excretion of electrolytes and prostanoids.
British journal of clinical pharmacology, , Volume: 25, Issue:3 | 1988 |
Excretion of primary prostanoids and their metabolites during acute volume expansion.
Prostaglandins, , Volume: 35, Issue:2 | 1988 |
The pharmacokinetics of flurbiprofen in younger and elderly patients with rheumatoid arthritis.
Journal of clinical pharmacology, , Volume: 32, Issue:1 | 1992 |
Onset of Action (1)
Bioavailability (12)
| Article | Year |
|---|
Vascular Nitric Oxide-Superoxide Balance and Thrombus Formation after Acute Exercise.
Medicine and science in sports and exercise, , Volume: 50, Issue:7 | 2018 |
Enhanced external counterpulsation improves peripheral artery function and glucose tolerance in subjects with abnormal glucose tolerance.
Journal of applied physiology (Bethesda, Md. : 1985), , Volume: 112, Issue:5 | 2012 |
NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.
Basic research in cardiology, , Volume: 103, Issue:5 | 2008 |
Estrogen therapy effects on different vasoactive factors in recent postmenopausal healthy women.
International journal of cardiology, , Feb-15, Volume: 107, Issue:2 | 2006 |
Role of peroxynitrite in the process of vascular tone regulation by nitric oxide and prostanoids--a nanotechnological approach.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 72, Issue:2 | 2005 |
Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2.
Clinical science (London, England : 1979), , Volume: 95, Issue:1 | 1998 |
Expression of acute otitis media after receptor blockade of platelet activating factor, thromboxane, and leukotrienes in the chinchilla.
The Annals of otology, rhinology, and laryngology, , Volume: 107, Issue:3 | 1998 |
Effect of omeprazole on the bioavailability of unmodified and phospholipid-complexed aspirin in rats.
Alimentary pharmacology & therapeutics, , Volume: 11, Issue:5 | 1997 |
Single intravenous and oral doses of fenflumizole: pharmacokinetics and effects on prostanoid formation.
Acta pharmacologica et toxicologica, , Volume: 57, Issue:2 | 1985 |
Biological half-life of prostacyclin and 6-oxo-PGF1 alpha levels in plasma of patients with colonic cancer.
Prostaglandins, leukotrienes, and medicine, , Volume: 22, Issue:3 | 1986 |
Increased bioavailability of enzymes of eicosanoid synthesis in hepatic and extrahepatic tissues after portacaval shunting.
Hepatology (Baltimore, Md.), , Volume: 10, Issue:2 | 1989 |
3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase.
Journal of medicinal chemistry, , Feb-21, Volume: 35, Issue:4 | 1992 |
Dosage (103)
| Article | Year |
|---|
Evaluation on antithrombotic effect of aspirin eugenol ester from the view of platelet aggregation, hemorheology, TXB2/6-keto-PGF1α and blood biochemistry in rat model.
BMC veterinary research, , Jun-14, Volume: 12, Issue:1 | 2016 |
Inhibition of prostacyclin and thromboxane biosynthesis in healthy volunteers by single and multiple doses of acetaminophen and indomethacin.
Clinical pharmacology in drug development, , Volume: 4, Issue:5 | 2015 |
Anti-myocardial ischemia effect of Syringa pinnatifolia Hemsl. by inhibiting expression of cyclooxygenase-1 and -2 in myocardial tissues of mice.
Journal of ethnopharmacology, , Jul-01, Volume: 187 | 2016 |
The effect of kisspeptin on the regulation of vascular tone.
Canadian journal of physiology and pharmacology, , Volume: 93, Issue:9 | 2015 |
A randomized cross-over comparison of short-term exposure of once-daily extended release tacrolimus and twice-daily tacrolimus on renal function in healthy volunteers.
Transplant international : official journal of the European Society for Organ Transplantation, , Volume: 27, Issue:12 | 2014 |
In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia.
Thrombosis and haemostasis, , Jul-03, Volume: 112, Issue:1 | 2014 |
VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist.
American journal of physiology. Regulatory, integrative and comparative physiology, , Volume: 297, Issue:4 | 2009 |
Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet.
Journal of clinical pharmacology, , Volume: 47, Issue:12 | 2007 |
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.
World journal of gastroenterology, , Oct-14, Volume: 13, Issue:38 | 2007 |
Isolated liver perfusion for regional chemotherapy in rats.
Hepatobiliary & pancreatic diseases international : HBPD INT, , Volume: 6, Issue:4 | 2007 |
[Physiological effects of cold and cool Chinese herbal medicine of channel tropism of stomach on rats with stomach-heat syndrome].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 32, Issue:11 | 2007 |
Human pharmacology of naproxen sodium.
The Journal of pharmacology and experimental therapeutics, , Volume: 322, Issue:2 | 2007 |
Protective effect of Weikang decoction and partial ingredients on model rat with gastric mucosa ulcer.
World journal of gastroenterology, , Feb-28, Volume: 11, Issue:8 | 2005 |
Endothelin-induced constriction of the ductus venosus in fetal sheep: developmental aspects and possible interaction with vasodilatory prostaglandin.
British journal of pharmacology, , Volume: 142, Issue:4 | 2004 |
Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects.
Circulation, , Mar-30, Volume: 109, Issue:12 | 2004 |
Allogeneic heart transplantation following xenogeneic bridging.
Transplant international : official journal of the European Society for Organ Transplantation, , Volume: 5 Suppl 1 | 1992 |
Cyclooxygenase-derived products modulate the increased intrahepatic resistance of cirrhotic rat livers.
Hepatology (Baltimore, Md.), , Volume: 37, Issue:1 | 2003 |
Determination of prostacyclin in plasma through a bioluminescent immunoassay for 6-keto-prostaglandin F1alpha: implication of dosage in patients with primary pulmonary hypertension.
Analytical chemistry, , Aug-01, Volume: 74, Issue:15 | 2002 |
[Effects of acetylsalvianolic acid A on arachidonic acid metabolism in platelets].
Yao xue xue bao = Acta pharmaceutica Sinica, , Volume: 33, Issue:1 | 1998 |
Serotonin hypersensitivity in aorta of two kidney-two clip hypertensive rats: calcium contribution and prostanoids-nitric oxide interactions.
Archives of physiology and biochemistry, , Volume: 109, Issue:1 | 2001 |
Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide?
Kidney & blood pressure research, , Volume: 24, Issue:2 | 2001 |
Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America, , Mar-13, Volume: 98, Issue:6 | 2001 |
Dose-response to inhaled aerosolized prostacyclin for hypoxemia due to ARDS.
Chest, , Volume: 117, Issue:3 | 2000 |
AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta.
The Journal of pharmacology and experimental therapeutics, , Volume: 290, Issue:1 | 1999 |
Transient loss of prostaglandin synthetic capacity in rabbit iris-ciliary body following anterior chamber paracentesis.
Ocular immunology and inflammation, , Volume: 6, Issue:4 | 1998 |
Effects of ridogrel, a thromboxane synthase inhibitor and receptor antagonist, on blood pressure in the spontaneously hypertensive rat.
Japanese journal of pharmacology, , Volume: 78, Issue:4 | 1998 |
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2.
Proceedings of the National Academy of Sciences of the United States of America, , Jan-05, Volume: 96, Issue:1 | 1999 |
Prostaglandin-independent stimulation of bone resorption in mouse calvariae and in isolated rat osteoclasts by thyroid hormones (T4, and T3).
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 217, Issue:2 | 1998 |
Effect of omeprazole on the bioavailability of unmodified and phospholipid-complexed aspirin in rats.
Alimentary pharmacology & therapeutics, , Volume: 11, Issue:5 | 1997 |
[The injury of liver sinusoidal endothelial cells in a rat's isolated liver perfusion (ILP) model for regional chemotherapy].
Zhonghua wai ke za zhi [Chinese journal of surgery], , Volume: 34, Issue:1 | 1996 |
Effect of aspirin dosage and enteric coating on platelet reactivity.
The American journal of cardiology, , Jul-15, Volume: 80, Issue:2 | 1997 |
Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], , Volume: 46, Issue:5 | 1997 |
Differential effect of benexate hydrochloride betadex on prostaglandin levels in stomach and inflammatory site in rats.
Japanese journal of pharmacology, , Volume: 72, Issue:2 | 1996 |
Abnormal prostanoid metabolism in lupus nephritis and the effects of a thromboxane A2 synthetase inhibitor, DP-1904.
Lupus, , Volume: 5, Issue:2 | 1996 |
[Short- and long-term effects of the new oral prostacyclin analogue, beraprost sodium, in patients with severe pulmonary hypertension].
Journal of cardiology, , Volume: 27, Issue:4 | 1996 |
Evaluation of the thromboxane A2 synthetase inhibitor OKY-046 in a warm ischemia-reperfusion rat model.
Transplantation, , May-27, Volume: 61, Issue:10 | 1996 |
Low-dose aspirin does not attenuate platelet aggregation or atherosclerosis in miniature swine but decreases production of aortic wall prostacyclin.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 53, Issue:5 | 1995 |
Gastric toxicity and prostaglandin content in rats dosed with two chemically similar, nonsteroidal anti-inflammatory agents.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), , Volume: 202, Issue:2 | 1993 |
Stimulation of prostaglandin biosynthesis mediates gastroprotective effect of rebamipide in rats.
Digestive diseases and sciences, , Volume: 38, Issue:8 | 1993 |
Tumor prostaglandin levels correlate with edema around supratentorial meningiomas.
Neurosurgery, , Volume: 33, Issue:2 | 1993 |
The effect of regular and enteric-coated aspirin on bleeding time, thromboxane, and prostacyclin.
Prostaglandins, leukotrienes, and essential fatty acids, , Volume: 49, Issue:1 | 1993 |
Role of prostacyclin in hemodynamic alterations in conscious rats with extrahepatic or intrahepatic portal hypertension.
Hepatology (Baltimore, Md.), , Volume: 18, Issue:3 | 1993 |
Effects of ridogrel on the prostacyclin-thromboxane ratio in nulliparous third trimester-pregnant rhesus monkeys.
Prostaglandins, , Volume: 45, Issue:6 | 1993 |
Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat. Differentiation of effects between nabumetone and etodolac.
Digestive diseases and sciences, , Volume: 39, Issue:3 | 1994 |
Effect of dose and method of administration of endotoxin on cell mediator release in neonatal calves.
American journal of veterinary research, , Volume: 54, Issue:12 | 1993 |
Angiotensin II metabolic clearance rate and pressor responses in nonpregnant and pregnant women.
American journal of obstetrics and gynecology, , Volume: 171, Issue:3 | 1994 |
Reduced thromboxane receptor affinity and vasoconstrictor responses in placentae from diabetic pregnancies.
Placenta, , Volume: 15, Issue:8 | 1994 |
Large increase in plasmatic 11-dehydro-TxB2 levels due to oral contraceptives.
Contraception, , Volume: 51, Issue:1 | 1995 |
Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking.
Journal of the American College of Cardiology, , Volume: 22, Issue:4 | 1993 |
Aspirin, prostacyclin and post-occlusive reactive hyperaemia in man.
Prostaglandins, leukotrienes, and medicine, , Volume: 9, Issue:4 | 1982 |
Prostacyclin substitution for heparin in long-term hemodialysis.
The American journal of medicine, , Volume: 73, Issue:5 | 1982 |
Comparison of alpha- and gamma-thrombin on lung fluid balance in anesthetized sheep.
Journal of applied physiology: respiratory, environmental and exercise physiology, , Volume: 57, Issue:5 | 1984 |
Hemodynamic effects of intravenous prostacyclin in stable angina pectoris.
The American journal of cardiology, , Sep-01, Volume: 52, Issue:5 | 1983 |
Relationship of renal hemodynamic and functional changes following intravascular contrast to the renin-angiotensin system and renal prostacyclin in the dog.
Investigative radiology, , Volume: 18, Issue:2 | |
Urinary excretion of prostacyclin and thromboxane A2 metabolites after angiotensin converting enzyme inhibition in hypertensive patients.
Prostaglandins, leukotrienes, and medicine, , Volume: 11, Issue:2 | 1983 |
Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment.
Journal of clinical psychopharmacology, , Volume: 4, Issue:2 | 1984 |
Purinoceptor mediated stimulation of prostacyclin release in the porcine pulmonary vasculature.
British journal of pharmacology, , Volume: 83, Issue:2 | 1984 |
Inhalation anesthetics augment oxidant-induced pulmonary vasoconstriction: evidence for a membrane effect.
Anesthesiology, , Volume: 63, Issue:6 | 1985 |
The effect of a thromboxane synthetase inhibitor, OKY-046, on urinary excretion of immunoreactive thromboxane B2 and 6-keto-prostaglandin F1 alpha in patients with ischemic cerebrovascular disease.
Stroke, , Volume: 16, Issue:2 | |
Kinetics of ibuprofen effect on platelet and endothelial prostanoid release.
Clinical pharmacology and therapeutics, , Volume: 37, Issue:3 | 1985 |
Study of the effects of cicletanine on prostanoids.
Arzneimittel-Forschung, , Volume: 35, Issue:11 | 1985 |
Experimental T-2 toxicosis in swine. I. Changes in cardiac output, aortic mean pressure, catecholamines, 6-keto-PGF1 alpha, thromboxane B2, and acid-base parameters.
Fundamental and applied toxicology : official journal of the Society of Toxicology, , Volume: 5, Issue:5 | 1985 |
[The effect of trapidil and the trapidil derivative AR 12463 on blood pressure and thromboxane formation in spontaneously hypertensive rats].
Die Pharmazie, , Volume: 42, Issue:5 | 1987 |
Dissociation between thromboxane generation and metastatic potential in cells from a murine fibrosarcoma. Studies with a selective thromboxane synthase inhibitor.
International journal of cancer, , Apr-15, Volume: 39, Issue:4 | 1987 |
A new combination therapy for selective and prolonged antiplatelet effect: results in the dog.
Stroke, , Volume: 17, Issue:3 | |
The antihypertensive action of hydrochlorothiazide and renal prostacyclin.
Clinical pharmacology and therapeutics, , Volume: 39, Issue:1 | 1986 |
Effects of a phenylbutazone paste in ponies: model of acute nonimmune inflammation.
American journal of veterinary research, , Volume: 47, Issue:11 | 1986 |
Individually controlled acetylsalicyclic acid (ASA) in the long-term treatment of patients with arteriosclerosis.
Biomedica biochimica acta, , Volume: 47, Issue:10-11 | 1988 |
Etodolac: effect on prostaglandin concentrations in gastric mucosa of rats.
Life sciences, , Mar-25, Volume: 36, Issue:12 | 1985 |
Possible prostacyclin involvement on disparate tonic responses to "in vitro" norepinephrine in circular and in longitudinal preparations from rat thoracic aorta.
Prostaglandins, leukotrienes, and medicine, , Volume: 30, Issue:1 | 1987 |
CGS 15435A, a thromboxane synthetase inhibitor with an extended duration of action: a comparison with dazoxiben.
European journal of pharmacology, , Jan-20, Volume: 133, Issue:3 | 1987 |
Gender-related variations and interaction of human neutrophil cyclooxygenase and oxidative burst metabolites.
Journal of leukocyte biology, , Volume: 40, Issue:2 | 1986 |
Human peritoneal eosinophils and formation of arachidonate cyclooxygenase products.
Scandinavian journal of immunology, , Volume: 23, Issue:5 | 1986 |
Correlation between trypsin binding to a specific receptor and prostacyclin production in cultured vascular endothelial cells.
Journal of cellular physiology, , Volume: 122, Issue:1 | 1985 |
A subchronic study of the effect of etodolac on the gastric mucosal prostaglandin levels in the rat.
Agents and actions, , Volume: 19, Issue:3-4 | 1986 |
Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase.
Circulation, , Volume: 73, Issue:6 | 1986 |
[Inhibitory effects of new-breviscapine on thrombosis in vivo].
Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 9, Issue:1 | 1989 |
[Piretanide in chronic and acute decompensated heart failure. Effect on hemodynamics and vasoactive hormones].
Medizinische Klinik (Munich, Germany : 1983), , Jun-15, Volume: 84, Issue:6 | 1989 |
Hypertension in bone marrow transplanted patients.
Acta clinica Belgica, , Volume: 44, Issue:5 | 1989 |
Endothelium-mediated dilations contribute to the polarity of the arterial wall in vasomotion induced by alpha 2-adrenergic agonists.
Journal of cardiovascular pharmacology, , Volume: 7, Issue:4 | |
[Relation of changes in plasma TXB2 PGF1alpha and differentiation of signs and symptoms in traditional Chinese medicine in severe icteric hepatitis].
Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:3 | 1990 |
[Effects of Codonopsis pilosulae on the synthesis of thromboxane A2 and prostacyclin].
Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, , Volume: 10, Issue:7 | 1990 |
Potentiation of anti-platelet aggregating activity of cilostazol with vascular endothelial cells.
Thrombosis research, , Feb-15, Volume: 57, Issue:4 | 1990 |
Effects of kinins on cultured arterial smooth muscle.
The American journal of physiology, , Volume: 258, Issue:2 Pt 1 | 1990 |
Selective inhibition of platelet cyclooxygenase with controlled release, low-dose aspirin.
Australian and New Zealand journal of medicine, , Volume: 20, Issue:5 | 1990 |
Age does not influence acute aspirin-induced gastric mucosal damage.
Gastroenterology, , Volume: 100, Issue:6 | 1991 |
Effect of aspirin on local prostaglandin production and serotonin accumulation in a canine model with coronary cyclic flow variations or thrombosis.
Journal of molecular and cellular cardiology, , Volume: 23, Issue:4 | 1991 |
Captopril, an ACE inhibitor, for optimizing reperfusion after acute myocardial infarction.
The Annals of thoracic surgery, , Volume: 52, Issue:4 | 1991 |
[Treatment of acute cerebral infarction with PGI2--evaluating the clinical effect and observation of dynamic changes in plasma TXB2 and 6-keto PGF1 alpha levels].
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, , Volume: 24, Issue:3 | 1991 |
Colloidal bismuth subcitrate evokes adaptive cytoprotection in rat gastric mucosa.
Acta medica Hungarica, , Volume: 48, Issue:3-4 | 1991 |
Imbalance between plasma levels of thromboxane B2 and 6-keto-prostaglandin F1 alpha during subacute endotoxin-induced hyperdynamic sepsis or multiple organ failure syndrome in sheep.
Circulatory shock, , Volume: 35, Issue:2 | 1991 |
Dose-related action of gonadotropin-releasing hormone on basal prostanoid production from the human term placenta.
American journal of obstetrics and gynecology, , Volume: 165, Issue:6 Pt 1 | 1991 |
The pharmacokinetics of flurbiprofen in younger and elderly patients with rheumatoid arthritis.
Journal of clinical pharmacology, , Volume: 32, Issue:1 | 1992 |
Inhibition of platelet aggregation by prostacyclin is attenuated after exercise in patients with angina pectoris.
American heart journal, , Volume: 123, Issue:2 | 1992 |
In vivo enhancement of platelet activating factor-induced prostacyclin production by OKY-046, a selective inhibitor of thromboxane A2 synthase.
Journal of cardiovascular pharmacology, , Volume: 17, Issue:4 | 1991 |
Influence of repeated administration of lithium on urinary excretion of prostaglandins in rats.
Japanese journal of pharmacology, , Volume: 57, Issue:4 | 1991 |
Noradrenaline-induced prostaglandin production by sympathetic postganglionic neurons is mediated by alpha 2-adrenergic receptors.
Journal of neurochemistry, , Volume: 57, Issue:4 | 1991 |
In vitro platelets/endothelial cells interactions in presence of acetylsalicylic acid at various dosages.
Thrombosis research, , Jan-01, Volume: 65, Issue:1 | 1992 |
Effects of a sustained thromboxane synthase inhibition on exercise-induced changes in eicosanoid formation, catecholamine concentration, and platelet aggregation in humans.
Clinical pharmacology and therapeutics, , Volume: 51, Issue:4 | 1992 |
Bridging to transplant: allogeneic heart transplantation after xenografting.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, , Volume: 11, Issue:4 Pt 2 | |
Interactions (8)
| Article | Year |
|---|
Panax Notoginseng Saponins Combined with Dual Antiplatelet Drugs Potentiates Anti-Thrombotic Effect with Alleviated Gastric Injury in A Carotid Artery Thrombosis Rat Model.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, , Volume: 31, Issue:8 | 2022 |
[Anti-platelet aggregation and anti-thrombotic mechanism of Trichosanthis Fructus combined with aspirin based on network pharmacology].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, , Volume: 44, Issue:8 | 2019 |
Panax quinquefolius saponins combined with dual antiplatelet drug therapy alleviate gastric mucosal injury and thrombogenesis through the COX/PG pathway in a rat model of acute myocardial infarction.
PloS one, , Volume: 13, Issue:3 | 2018 |
Prevention of atherosclerosis by Yindan Xinnaotong capsule combined with swimming in rats.
BMC complementary and alternative medicine, , Apr-08, Volume: 15 | 2015 |
Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury.
Arzneimittel-Forschung, , Volume: 62, Issue:12 | 2012 |
Antithrombin ameliorates endotoxin-induced organ dysfunction more efficiently when combined with danaparoid sodium than with unfractionated heparin.
Intensive care medicine, , Volume: 31, Issue:8 | 2005 |
Mycophenolate mofetil combined with a cyclooxygenase-2 inhibitor ameliorates murine lupus nephritis.
Kidney international, , Volume: 60, Issue:2 | 2001 |
Simultaneous determination of the primary prostanoids prostaglandin E2, prostaglandin F2 alpha and 6-oxoprostaglandin F1 alpha by immunoaffinity chromatography in combination with negative ion chemical ionization gas chromatography-tandem mass spectrometr
Journal of chromatography, , Sep-29, Volume: 494 | 1989 |