Peptidyl-prolyl cis-trans isomerase FKBP3

A peptidyl-prolyl cis-trans isomerase FKBP3 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q00688]

Synonyms

PPIase FKBP3;
EC 5.2.1.8;
25 kDa FK506-binding protein;
25 kDa FKBP;
FKBP-25;
FK506-binding protein 3;
FKBP-3;
Immunophilin FKBP25;
Rapamycin-selective 25 kDa immunophilin;
Rotamase

Research

Bioassay Publications (1)

Timeframe	Studies on this Protein(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	1 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Compounds (1)

Drugs with Inhibition Measurements

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
cycloheximide	Homo sapiens (human)	Ki	124.0000	1	1

Enables

This protein enables 5 target(s):

Target	Category	Definition
RNA binding	molecular function	Binding to an RNA molecule or a portion thereof. [GOC:jl, GOC:mah]
peptidyl-prolyl cis-trans isomerase activity	molecular function	Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). [EC:5.2.1.8]
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
FK506 binding	molecular function	Binding to a 23-membered macrolide lactone FK506. [GOC:jl]
signaling receptor activity	molecular function	Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. [GOC:bf, GOC:signaling]

Located In

This protein is located in 1 target(s):

Target	Category	Definition
nucleus	cellular component	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]

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