Compounds > musk ketone
Page last updated: 2024-09-20

musk ketone

Description

musk ketone: increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6669
CHEMBL ID1877463
CHEBI ID174791
SCHEMBL ID113330
MeSH IDM0098790

Synonyms (84)

Synonym
STK725128
CHEBI:174791
acetophenone, 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitro-
ethanone, 1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-
2,6-dimethyl-3,5-dinitro-4-tert-butylacetophenone
acetophenone,6'-dimethyl-3',5'-dinitro-
nsc15339
musk ketone
ethanone,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]-
4'-tert-butyl-2',5'-dinitroacetophenone
81-14-1
nsc-15339
2-acetyl-5-tert-butyl-4,6-dinitroxylene
einecs 201-328-9
2,6-dimethyl-3,5-dinitro-4-t-butylacetophenone
nsc 15339
ethanone, 1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)-
2,6-dinitro-3,5-dimethyl-4-acetyl-tert-butylbenzene
ccris 4677
4'-tert-butyl-2',6'-dimethyl-3',5'-dinitroacetophenone
1-(4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl)ethanone
4-tert-butyl-3,5-dinitro-2,6-dimethylacetophenone
ai3-02440
3,5-dinitro-2,6-dimethyl-4-tert-butylacetophenone
brn 2062638
musk ketone, >=98%
NCGC00164404-01
1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone
ketone moschus, >=97.0% (n)
AC-11085
A840051
1-(4-tert-butyl-2,6-dimethyl-3,5-dinitro-phenyl)ethanone
4-07-00-00808 (beilstein handbook reference)
unii-483v3e1l6j
483v3e1l6j ,
hsdb 7694
dtxsid6025690 ,
cas-81-14-1
dtxcid405690
NCGC00255386-01
tox21_301627
BBL011671
AKOS005524284
FT-0629036
1-tert-butyl-3,5-dimethyl-2,6-dinitro-4-acetylbenzene
musk ketone [hsdb]
musk ketone [inci]
2,6 dimethyl-4-tert-butyl-3,5-dinitroacetophenone
4-tert-butyl-2,6-dimethyl-3,5-dinitroacetophenone
4-aceto-3,5-dimethyl-2,6-dinitro-tert-butylbenzene
3,5-dinitro-4-tert-butyl-2,6-dimethylacetophenone
2,6-dimethyl-3,5-dinitro-4-tert-butyl acetophenone
SCHEMBL113330
mfcd00024271
1-[4-(tert-butyl)-2,6-dimethyl-3,5-dinitrophenyl]ethan-1-one
W-104216
CHEMBL1877463
4-t-butyl-2,6-dimethyl-3,5-dinitroacetophenone
2,6-dinitro-3,5-dimethyl-4-acetyl-tertbutylbenzene
WXCMHFPAUCOJIG-UHFFFAOYSA-N
4-tert-butyl-2,6-dimethyl-3,5-dinitroactophenone
1-acetyl-4-tert-butyl-2,6-dimethyl-3,5-dinitrobenzene
ketone musk
3,5-dinitro-2,6-dimethyl-4-tert-butyl acetophenone
1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]ethanone
ketone moschus
1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone #
1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethan-1-one
SR-01000324027-1
sr-01000324027
musk ketone 10 microg/ml in cyclohexane
ketonmoschus
acetyl-dinitro-butyl-xylene
1-[4-(1,1-dimethylethyl)-2,6-dimethyl-3,5-dinitrophenyl]ethanone, 9ci
4'-tert-butyl-2', 6'-dimethyl-3',5'-dinitroacetophenone
4'-tert-butyl-2',6'-dimethyl-3',5'-dinitro-acetophenone
dinitro-tert-butylxylyl methyl ketone
musk ketone;3-methylcyclopentadecanone
3',5'-dinitro-2',6'-dimethyl-4'-tert-butylacetophenone
Q1948992
FS-4310
AC-34811
CS-0018535
HY-N2045

Research Excerpts

Overview

ExcerptReference
"Musk ketone is a widely used artificial fragrance which has been identified in human fatty tissue and milk. "( Freywald, C; Jenter, C; Knasmüller, S; Mersch-Sundermann, V; Parzefall, W; Schneider, H, 2001)

Drug Classes (1)

ClassDescription
aromatic ketoneA ketone in which the carbonyl group is attached to an aromatic ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (13)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
acetylcholinesteraseHomo sapiens (human)Potency79.64070.002541.796015,848.9004AID1347395
pregnane X receptorRattus norvegicus (Norway rat)Potency39.81070.025127.9203501.1870AID651751
AR proteinHomo sapiens (human)Potency0.00450.000221.22318,912.5098AID588515
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency30.63790.000657.913322,387.1992AID1259378
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency57.66580.001022.650876.6163AID1224838; AID1224839; AID1224893
retinoid X nuclear receptor alphaHomo sapiens (human)Potency22.25870.000817.505159.3239AID1159527; AID1159531; AID588544
farnesoid X nuclear receptorHomo sapiens (human)Potency39.81070.375827.485161.6524AID588526
pregnane X nuclear receptorHomo sapiens (human)Potency46.61310.005428.02631,258.9301AID1346982; AID720659
estrogen nuclear receptor alphaHomo sapiens (human)Potency30.63790.000229.305416,493.5996AID743080
thyroid stimulating hormone receptorHomo sapiens (human)Potency7.37400.001628.015177.1139AID1224843; AID1224895
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency34.665419.739145.978464.9432AID1159509
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency43.64120.057821.109761.2679AID1159528
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency68.58960.000323.4451159.6830AID743065; AID743067
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (79)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (5.06)18.7374
1990's17 (21.52)18.2507
2000's22 (27.85)29.6817
2010's30 (37.97)24.3611
2020's6 (7.59)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (1.23%)5.53%
Reviews5 (6.17%)6.00%
Case Studies1 (1.23%)4.05%
Observational0 (0.00%)0.25%
Other74 (91.36%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
musk[no description available]medium150macrolide
musk ambrette (artificial)[no description available]medium191C-nitro compound
galaxolide[no description available]medium270isochromenes;
organic heterotricyclic compound		fragrance
moskene[no description available]medium150
musk xylene[no description available]medium531C-nitro compoundcarcinogenic agent;
explosive;
fragrance
musk tibetine[no description available]medium120
benzophenone[no description available]medium10benzophenonesphotosensitizing agent;
plant metabolite
dinitrobenzenes[no description available]medium211
acetyl methyl tetramethyl tetralin[no description available]medium270tetralins
6,7-dihydro-1,1,2,3,3-pentamethyl-4-(5h)indanone[no description available]medium30
tetrabromobisphenol a[no description available]medium10brominated flame retardant;
bromobisphenol
triclosan[no description available]medium20aromatic ether;
dichlorobenzene;
monochlorobenzenes;
phenols		antibacterial agent;
antimalarial;
drug allergen;
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
fungicide;
persistent organic pollutant;
xenobiotic
acetyl tert-butyl dimethylindan[no description available]medium70indanes
ozone[no description available]medium10elemental molecule;
gas molecular entity;
reactive oxygen species;
triatomic oxygen		antiseptic drug;
disinfectant;
electrophilic reagent;
greenhouse gas;
mutagen;
oxidising agent;
tracer
rhodamine b[no description available]medium10organic chloride salt;
xanthene dye		fluorescent probe;
fluorochrome;
histological dye
quinidine[no description available]medium10cinchona alkaloidalpha-adrenergic antagonist;
anti-arrhythmia drug;
antimalarial;
drug allergen;
EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor;
EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor;
muscarinic antagonist;
P450 inhibitor;
potassium channel blocker;
sodium channel blocker
phencyclidine[no description available]medium10benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
chlorodiphenyl (54% chlorine)[no description available]medium10
phenobarbital[no description available]medium10barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
benzo(a)pyrene[no description available]medium10ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
oxoamide[no description available]low00aromatic ketone
4-oxo-4-(3-pyridyl)butanoic acid[no description available]low00aromatic ketone;
monocarboxylic acid;
pyridines
bupropion[no description available]low00aromatic ketone;
monochlorobenzenes;
secondary amino compound		antidepressant;
environmental contaminant;
xenobiotic
bw 306u[no description available]low00aromatic ketone
kynurenine[no description available]low00aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline		human metabolite
monomethylpropion[no description available]low00aromatic ketone;
secondary amino compound
ro 48-8071[no description available]low00aromatic ether;
aromatic ketone;
bromobenzenes;
monofluorobenzenes;
olefinic compound;
tertiary amino compound		antineoplastic agent;
EC 5.4.99.7 (lanosterol synthase) inhibitor
amiodarone[no description available]low001-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
anisindione[no description available]low00aromatic ketone;
beta-diketone		anticoagulant;
vitamin K antagonist
acetovanillone[no description available]low00acetophenones;
aromatic ketone;
methyl ketone		antirheumatic drug;
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug;
plant metabolite
benzbromarone[no description available]low001-benzofurans;
aromatic ketone		uricosuric drug
bromperidol[no description available]low00aromatic ketone
buflomedil[no description available]low00aromatic ketone
celiprolol[no description available]low00aromatic ketone
droperidol[no description available]low00aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
dyclonine[no description available]low00aromatic ketone;
piperidines		topical anaesthetic
eperisone[no description available]low00aromatic ketone;
piperidines
eprazinone[no description available]low00aromatic ketone;
ether;
N-alkylpiperazine		mucolytic
ethacrynic acid[no description available]low00aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid		EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic
haloperidol[no description available]low00aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
ketanserin[no description available]low00aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
ketorolac[no description available]low00amino acid;
aromatic ketone;
monocarboxylic acid;
pyrrolizines;
racemate		analgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
lofepramine[no description available]low00aromatic ketone;
dibenzoazepine;
monochlorobenzenes;
tertiary amino compound		antidepressant
mebendazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
nocodazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator
metyrapone[no description available]low00aromatic ketoneantimetabolite;
diagnostic agent;
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
moperone[no description available]low00aromatic ketone
phenindione[no description available]low00aromatic ketone;
beta-diketone		anticoagulant
pifithrin[no description available]low00aromatic ketone
pipamperone[no description available]low00aromatic ketone;
bipiperidines;
monocarboxylic acid amide;
organofluorine compound;
tertiary amino compound		dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
pirenperone[no description available]low00aromatic ketone
propafenone[no description available]low00aromatic ketone;
secondary alcohol;
secondary amino compound		anti-arrhythmia drug
propiomazine[no description available]low00aromatic ketone;
phenothiazines;
tertiary amino compound		dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
sedative;
serotonergic antagonist
raloxifene[no description available]low001-benzothiophenes;
aromatic ketone;
N-oxyethylpiperidine;
phenols		bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
spiperone[no description available]low00aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
suprofen[no description available]low00aromatic ketone;
monocarboxylic acid;
thiophenes		antirheumatic drug;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
tiaprofenic acid[no description available]low00aromatic ketone;
monocarboxylic acid;
thiophenes		drug allergen;
non-steroidal anti-inflammatory drug
tolmetin[no description available]low00aromatic ketone;
monocarboxylic acid;
pyrroles		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
tolperisone[no description available]low00aromatic ketone
trifluperidol[no description available]low00aromatic ketone
zomepirac[no description available]low00aromatic ketone;
monocarboxylic acid;
monochlorobenzenes;
pyrroles		cardiovascular drug;
non-steroidal anti-inflammatory drug
acepromazine[no description available]low00aromatic ketone;
methyl ketone;
phenothiazines;
tertiary amino compound		phenothiazine antipsychotic drug
benziodarone[no description available]low00aromatic ketone
quinophthalone[no description available]low00aromatic ketone;
beta-diketone;
quinolines		dye
2-acetylthiophene[no description available]low00aromatic ketone
diethylpropion[no description available]low00aromatic ketone;
tertiary amine		appetite depressant
adrenalone[no description available]low00aromatic ketone
dibenzoylmethane[no description available]low00aromatic ketone;
beta-diketone		antimutagen;
antineoplastic agent;
metabolite
pyrazolanthrone[no description available]low00anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector
benzil[no description available]low00alpha-diketone;
aromatic ketone
4'-(chloroacetyl)acetanilide[no description available]low00acetamides;
alpha-chloroketone;
aromatic ketone
3-acetylpyridine[no description available]low00aromatic ketone
ninhydrin[no description available]low00aromatic ketone;
beta-diketone;
indanones;
ketone hydrate		colour indicator;
human metabolite
capillin[no description available]low00aromatic ketone;
ynone
gallacetophenone[no description available]low00aromatic ketone
1-phenyl-1,2-propanedione[no description available]low00alpha-diketone;
aromatic ketone		plant metabolite
1,3-indandione[no description available]low00aromatic ketone;
beta-diketone;
indanones
phenacylamine[no description available]low00aromatic ketone
2-acetylpyrrole[no description available]low00aromatic ketone;
methyl ketone;
pyrroles
2-acetylpyridine[no description available]low00aromatic ketone
pyrovalerone[no description available]low00aromatic ketone
2-acetylfuran[no description available]low00aromatic ketone;
furans;
methyl ketone
sapropterin[no description available]low00aromatic ketone
fluanisone[no description available]low00aromatic ketone
3-Acetyl-2,4-dimethylpyrrole[no description available]low00aromatic ketone
metylperon[no description available]low00aromatic ketone
azaperone[no description available]low00aminopyridine;
aromatic ketone;
monofluorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist
Propioveratrone[no description available]low00aromatic ketone
benperidol[no description available]low00aromatic ketone
2,4-diacetylphloroglucinol[no description available]low00aromatic ketone;
benzenetriol;
diketone;
methyl ketone		antifungal agent;
bacterial metabolite
4-benzoylpyridine[no description available]low00aromatic ketone
pyoluteorin[no description available]low00aromatic ketone;
beta-hydroxy ketone;
diol;
organochlorine compound;
organochlorine pesticide;
polyketide;
pyrroles;
resorcinols		antibacterial agent;
antifungal agent;
apoptosis inducer;
bacterial metabolite;
marine metabolite
flubendazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester;
organofluorine compound		antinematodal drug;
teratogenic agent
4-ipomeanol[no description available]low00aromatic ketone
ticrynafen[no description available]low00aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes		antihypertensive agent;
hepatotoxic agent;
loop diuretic
celiprolol hydrochloride[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-(1-imidazolyl)ethanone[no description available]low00aromatic ketone
enoximone[no description available]low00aromatic ketone
bupropion hydrochloride[no description available]low00aromatic ketone
3-oxo-3-phenylpropanenitrile[no description available]low00aromatic ketone;
beta-ketonitrile
fenofibric acid[no description available]low00aromatic ketone;
chlorobenzophenone;
monocarboxylic acid		drug metabolite;
marine xenobiotic metabolite
inaperisone[no description available]low00aromatic ketone
valerophenone[no description available]low00aromatic ketoneplant metabolite;
volatile oil component
2,4,6-trihydroxyacetophenone[no description available]low00aromatic ketone;
benzenetriol;
methyl ketone		MALDI matrix material;
plant metabolite
perilla ketone[no description available]low00aromatic ketone
butofilolol[no description available]low00aromatic ketone
2,6-dihydroxyacetophenone[no description available]low00aromatic ketone
2',4'-Dimethoxypropiophenone[no description available]low00aromatic ketone
propipocaine[no description available]low00aromatic ketone
hp 873[no description available]low001,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist
prifelone[no description available]low00aromatic ketone
metamfepramone[no description available]low00aromatic ketone
1-(2,4-dihydroxyphenyl)-1-hexanone[no description available]low00aromatic ketone
1-(2,4-Dihydroxyphenyl)-1-butanone[no description available]low00aromatic ketone
isoxaflutole[no description available]low00(trifluoromethyl)benzenes;
aromatic ketone;
cyclopropanes;
isoxazoles;
sulfone		agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
proherbicide
sulcotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclohexanones;
sulfone		carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
tolperisone hydrochloride[no description available]low00aromatic ketone
beta-(4-fluorobenzoyl)propionic acid[no description available]low00aromatic ketone
lobeline[no description available]low00aromatic ketone;
piperidine alkaloid;
tertiary amine		nicotinic acetylcholine receptor agonist
aflatoxin q1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human xenobiotic metabolite
desethylamiodarone[no description available]low00aromatic ketone
ly 117018[no description available]low001-benzothiophenes;
aromatic ketone;
N-alkylpyrrolidine;
phenols		bone density conservation agent;
estrogen receptor antagonist;
estrogen receptor modulator
fpl 55712[no description available]low00aromatic ketone
(6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide[no description available]low00aromatic ketone
4-hydoxy-1-(3-pyridyl)-1-butanone[no description available]low00aromatic ketone
1-[4-[2-hydroxy-3-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]propoxy]phenyl]-1-propanone[no description available]low00aromatic ketone
3-(1-piperidinyl)-1-(4-propan-2-yloxyphenyl)-1-propanone[no description available]low00aromatic ketone
3-n-methylspiperone[no description available]low00aromatic ketone
ly 255283[no description available]low00aromatic ketone
eperisone[no description available]low00aromatic ketone
n-(4-aminophenethyl)spiroperidol[no description available]low00aromatic ketone
esonarimod[no description available]low00aromatic ketone
oxoline[no description available]low00aromatic ketone;
tetralins		geroprotector
n-acetyl-n-formyl-5-methoxykynurenamine[no description available]low00aromatic ketone
4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine[no description available]low00aromatic ketone
mesotrione[no description available]low00aromatic ketone;
beta-triketone;
C-nitro compound;
sulfone		carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic
rs 67333[no description available]low00aromatic ketone
aflatoxin b1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
dronedarone[no description available]low001-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
environmental contaminant;
xenobiotic
alpha-pyrrolidinopropiophenone[no description available]low00aromatic ketone
(1-tert-butyl-5-phenyl-3-pyrrolyl)-phenylmethanone[no description available]low00aromatic ketone
veratrone[no description available]low00aromatic ketone;
dimethoxybenzene;
primary alcohol
7-benzoyl-3-chloroindolizine-1,2-dicarboxylic acid dimethyl ester[no description available]low00aromatic ketone
bromodeoxytopsentin[no description available]low00aromatic ketone;
bromoindole;
imidazoles;
indole alkaloid		antibacterial agent;
EC 2.7.1.40 (pyruvate kinase) inhibitor;
marine metabolite
amiodarone hydrochloride[no description available]low00aromatic ketone
knipholone[no description available]low00aromatic ketone;
dihydroxyanthraquinone;
methoxybenzenes;
methyl ketone;
polyphenol;
resorcinols		antineoplastic agent;
antioxidant;
antiplasmodial drug;
leukotriene antagonist;
metabolite
alpha bitter acid[no description available]low00aromatic ketone;
cyclic ketone;
diketone;
tertiary alpha-hydroxy ketone;
triol		antibacterial drug;
antioxidant;
cyclooxygenase 2 inhibitor;
metabolite
2-Acetylthiazole[no description available]low00aromatic ketone
1-[3-acetyl-5-[(4-bromophenyl)-oxomethyl]-1,3,7-triazabicyclo[3.3.1]nonan-7-yl]ethanone[no description available]low00aromatic ketone
LSM-42773[no description available]low00aromatic ketone
1-(4-methylphenyl)-2-(1H-1,2,4-triazol-5-ylthio)ethanone[no description available]low00aromatic ketone
3-(4-fluoroanilino)-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
(5-methoxy-3-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone[no description available]low00aromatic ketone
(2-amino-5-methyl-3-thiophenyl)-thiophen-2-ylmethanone[no description available]low00aromatic ketone;
thiophenes
1-(2,5-dimethoxyphenyl)-2-[[5-(2-furanyl)-4-propyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(1,3-benzodioxol-5-ylmethyl)-3-hydroxy-3-[2-(4-methylphenyl)-2-oxoethyl]-2-indolone[no description available]low00aromatic ketone
2-[(5-amino-1-phenacyl-1,2,4-triazol-3-yl)thio]-N-(3-cyano-4,5-dimethyl-2-thiophenyl)acetamide[no description available]low00aromatic ketone
2-[[1-(2-methoxyethyl)-5-tetrazolyl]thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(4-methoxyphenyl)-2-(5-thiophen-2-yl-2-tetrazolyl)ethanone[no description available]low00aromatic ketone
1-(3-methoxyphenyl)-2-[[4-methyl-5-[[(4-phenyl-2-thiazolyl)amino]methyl]-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(5-chloro-2-methoxyphenyl)-2-[(4,6-diamino-2-pyrimidinyl)thio]ethanone[no description available]low00aromatic ketone
2-[(5-methyl-1H-1,2,4-triazol-3-yl)thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(4-chlorophenyl)-2-[[4-ethyl-5-(2-methyl-3-furanyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dichlorophenyl)-2-[[4-(2-furanylmethyl)-5-(3-pyridinyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
(4-chloro-5-hydroxy-3-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dione[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(2-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-[[4-(2-furanylmethyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-thiophen-2-ylacetamide[no description available]low00aromatic ketone
4-thiomorpholinecarbodithioic acid [2-(4-chlorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
1-[4-[(2-methyl-4-quinolinyl)amino]phenyl]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[(4,6-dimethyl-2-pyrimidinyl)thio]ethanone[no description available]low00aromatic ketone
1-(4-Chlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)thio]ethan-1-one[no description available]low00aromatic ketone
4-(4-ethoxyphenyl)-4-oxobutanoic acid[no description available]low00aromatic ketone
4-bromo-N-phenacylbenzamide[no description available]low00aromatic ketone
N1-[2-(4-chlorophenyl)-2-oxoethyl]-4-chlorobenzamide[no description available]low00aromatic ketone
1-[4-[(4,6-dimethyl-2-pyrimidinyl)amino]phenyl]ethanone[no description available]low00aromatic ketone
4-amino-2-(phenacylthio)-5-pyrimidinecarboxylic acid ethyl ester[no description available]low00aromatic ketone
(3-hydroxy-5,6,7,8-tetrahydro-4H-cyclohepta[d]imidazol-2-yl)-phenylmethanone[no description available]low00aromatic ketone
2-fluoro-N-phenacylbenzamide[no description available]low00aromatic ketone
2-(Benzotriazol-1-yl)-1-(4-bromophenyl)ethanone[no description available]low00aromatic ketoneanticoronaviral agent
2-(4-methylanilino)-1-(4-nitrophenyl)ethanone[no description available]low00aromatic ketone
1-(3-((2',4'-Dimethyl-[4,5'-bithiazol]-2-yl)amino)phenyl)ethanone[no description available]low00aromatic ketone
1-[4-(1-azepanyl)-3-fluorophenyl]-1-propanone[no description available]low00aromatic ketone
2-(8-quinolinylthio)acetic acid phenacyl ester[no description available]low00aromatic ketone
2-(4-ethoxyanilino)-1-(4-methylphenyl)ethanone[no description available]low00aromatic ketone
1-[4-[[6-methyl-2-(methylthio)-5-prop-2-enyl-4-pyrimidinyl]amino]phenyl]ethanone[no description available]low00aromatic ketone
(4-methoxyphenyl)-(3-methyl-2-propyl-4-imidazolyl)methanone[no description available]low00aromatic ketone
5-[(5-acetyl-2-propan-2-yloxyphenyl)methyl]-6-hydroxy-2-sulfanylidene-1H-pyrimidin-4-one[no description available]low00aromatic ketone
N-(5-benzoyl-4-phenyl-2-thiazolyl)carbamic acid methyl ester[no description available]low00aromatic ketone
2-chloro-N-[5-ethyl-3-[(4-methylphenyl)-oxomethyl]-2-thiophenyl]acetamide[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-(2-pyridinylthio)ethanone[no description available]low00aromatic ketone
N-(3-acetylphenyl)-2-thiophen-2-ylacetamide[no description available]low00aromatic ketone
3-(4-bromoanilino)-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
3-anilino-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
1-(5-ethyl-2,4-dihydroxyphenyl)-2-(2-fluorophenoxy)ethanone[no description available]low00aromatic ketone
3-[1-(4-acetylphenyl)-5-thiophen-2-yl-2-pyrrolyl]propanoic acid[no description available]low00aromatic ketone
(7-methoxy-2-benzofuranyl)-(4-nitrophenyl)methanone[no description available]low00aromatic ketone
4-[2-(3-methoxyphenyl)-2-oxoethoxy]benzoic acid methyl ester[no description available]low00aromatic ketone
4-phenacyloxybenzoic acid methyl ester[no description available]low00aromatic ketone
1-(2-hydroxyphenyl)-2-(2H-tetrazol-5-yl)ethanone[no description available]low00aromatic ketone
2-(methylamino)benzoic acid [2-(4-fluorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[(4-methyl-2-pyrimidinyl)thio]-1-(3-nitrophenyl)ethanone[no description available]low00aromatic ketone
3-[[(3-acetylanilino)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester[no description available]low00aromatic ketone
1-(3-acetylphenyl)-3-(2-pyridinylmethyl)urea[no description available]low00aromatic ketone
1-(4-acetylphenyl)-3-[2-(4-fluorophenyl)ethyl]thiourea[no description available]low00aromatic ketone
1-phenyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanone[no description available]low00aromatic ketone
3-tert-butyl-7-[[2-(4-methylphenyl)-2-oxoethyl]thio]-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one[no description available]low00aromatic ketone
LSM-4563[no description available]low00aromatic ketone
1-[4-[3-[5-(2-furanyl)-1H-pyrazol-3-yl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]ethanone[no description available]low00aromatic ketone
1,3-diphenyl-4-pyrazolecarboxylic acid [2-(4-methyl-3-nitrophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
Silica aerogel[no description available]low00aromatic ketone
2-[[5-(1-benzotriazolylmethyl)-4-methyl-1,2,4-triazol-3-yl]thio]-1-(2-fluorophenyl)ethanone[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[[1-(3,5-dimethoxyphenyl)-5-tetrazolyl]thio]acetamide[no description available]low00aromatic ketone
3,4-dimethoxybenzoic acid [2-(3,4-dimethoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[2-[2-(4-chlorophenyl)-2-oxoethoxy]phenyl]isoindole-1,3-dione[no description available]low00aromatic ketone
2-[[5-(7-methoxy-2-benzofuranyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(4-methoxyphenyl)ethanone[no description available]low00aromatic ketone
2-[[4,6-bis(1-piperidinyl)-1,3,5-triazin-2-yl]thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(2,5-dimethylphenyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]ethanone[no description available]low00aromatic ketone
3-methyl-1,5-dithiophen-2-ylpentane-1,5-dione[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
2-[[5-(3-chlorophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
(4-chlorophenyl)-(5-hydroxy-2-methyl-4,6-dinitro-3-benzofuranyl)methanone[no description available]low00aromatic ketone
1-(3,4-dimethylphenyl)-2-[[5-[[2-(4-ethoxyanilino)-4-thiazolyl]methyl]-1,3,4-oxadiazol-2-yl]thio]ethanone[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-[(2-propyl-4-quinazolinyl)thio]ethanone[no description available]low00aromatic ketone
(5-chloro-2-hydroxyphenyl)-[2-ethyl-3-(4-fluorophenyl)-6-pyrazolo[1,5-a]pyrimidinyl]methanone[no description available]low00aromatic ketone
N,N-dimethylcarbamothioic acid O-[4-[2-[(4-chlorophenyl)thio]-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
4-[(4-tert-butylphenyl)-oxomethyl]-N-[2-(2-pyridinyl)ethyl]-1H-pyrrole-2-carboxamide[no description available]low00aromatic ketone
(4-chlorophenyl)-[5-(4-morpholinyl)-4-(2-pyridinyl)-2-thiophenyl]methanone[no description available]low00aromatic ketone
N,N-dimethylcarbamic acid [4-[2-(benzenesulfonyl)-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
N,N-dimethylcarbamic acid [4-[2-(4-fluorophenyl)sulfonyl-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
2-chloro-1-[1-(2-furanylmethyl)-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
N-[(phenacylamino)-sulfanylidenemethyl]-2-furancarboxamide[no description available]low00aromatic ketone
3-phenylpropionylglycine[no description available]low00aromatic ketone
4-amino-5-[(4-methylphenyl)-oxomethyl]-2-(prop-2-enylamino)-3-thiophenecarbonitrile[no description available]low00aromatic ketone
2-amino-4-[[2-(4-bromophenyl)-2-oxoethyl]thio]-3-azaspiro[5.5]undeca-1,4-diene-1,5-dicarbonitrile[no description available]low00aromatic ketone
2-[[4-ethyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]-1-(4-methylphenyl)ethanone[no description available]low00aromatic ketone
7-amino-9-(phenacylthio)-8-azaspiro[4.5]deca-6,9-diene-6,10-dicarbonitrile[no description available]low00aromatic ketone
6-(bromomethyl)-1,3-dimethyl-5-[(4-nitrophenyl)-oxomethyl]pyrimidine-2,4-dione[no description available]low00aromatic ketone
1-(2,4-dimethylphenyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanone[no description available]low00aromatic ketone
4-(4-acetylphenoxy)butanoic acid [5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methyl ester[no description available]low00aromatic ketone
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanone[no description available]low00aromatic ketone
2-chloro-1-[2,5-dimethyl-1-(5-methyl-3-isoxazolyl)-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
2-[2-[[5-cyano-1-(3-methoxypropyl)-6-oxo-3-pyridinyl]-oxomethyl]-4-methoxyphenoxy]-N-(5-methyl-3-isoxazolyl)acetamide[no description available]low00aromatic ketone
1-[2-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-oxoethyl]pyrrolidine-2,5-dione[no description available]low00aromatic ketone
3,5-dimethyl-4-isoxazolecarboxylic acid [2-(4-amino-1-methyl-2,6-dioxo-3-propyl-5-pyrimidinyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[3-[(4-chlorophenyl)-oxomethyl]-6-methoxy-4-oxo-1-quinolinyl]-N-(4-fluorophenyl)acetamide[no description available]low00aromatic ketone;
quinolines
1-[4-[(2-amino-5-thiazolyl)methyl]phenyl]ethanone[no description available]low00aromatic ketone
[9-(4-ethoxyphenyl)sulfonyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone[no description available]low00aromatic ketone;
quinolines
4-chloro-N-[(phenacylamino)-sulfanylidenemethyl]benzamide[no description available]low00aromatic ketone
N-[(phenacylamino)-sulfanylidenemethyl]cyclohexanecarboxamide[no description available]low00aromatic ketone
4-(4-chlorophenyl)-4-oxobutanoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester[no description available]low00aromatic ketone
1-(2-chlorophenyl)-2-(3,5-dimethyl-4-nitro-1-pyrazolyl)ethanone[no description available]low00aromatic ketone
[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-[4-(1-piperidinylsulfonyl)phenyl]methanone[no description available]low00aromatic ketone
4-(dimethylamino)benzoic acid [2-(2-methoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-chloro-3-pyridinecarboxylic acid [2-(4-fluorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
3-(1,3-benzothiazol-2-yl)propanoic acid phenacyl ester[no description available]low00aromatic ketone
5-[(2-hydroxy-5-methylphenyl)-oxomethyl]-N,1-bis[2-(4-methoxyphenyl)ethyl]-2-oxo-3-pyridinecarboxamide[no description available]low00aromatic ketone
2-[(1-oxido-2-pyridin-1-iumyl)thio]-1-(4-phenylphenyl)ethanone[no description available]low00aromatic ketone
2-(1H-benzimidazol-2-yl)-1-(3-nitrophenyl)ethanone[no description available]low00aromatic ketone
2-[[2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl]thio]-3-pyridinecarboxylic acid[no description available]low00aromatic ketone
2-[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]-1-(2-methoxyphenyl)ethanone[no description available]low00aromatic ketone
2-chloro-1-[1-[2-(4-chlorophenyl)ethyl]-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
2-chloro-3-pyridinecarboxylic acid [2-(4-ethylphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
3-(4-acetylphenyl)-1-(phenylmethyl)-1-propylthiourea[no description available]low00aromatic ketone
2-anilinobenzoic acid [2-(4-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
N-(2-acetylphenyl)-2-(2-oxo-1-quinoxalinyl)acetamide[no description available]low00aromatic ketone
2-[[5-(5-bromo-2-furanyl)-4-(phenylmethyl)-1,2,4-triazol-3-yl]thio]-1-(2-fluorophenyl)ethanone[no description available]low00aromatic ketone
4,5-dichloro-2-[2-[2,5-dimethyl-1-(2,2,2-trifluoroethyl)-3-pyrrolyl]-2-oxoethyl]-3-pyridazinone[no description available]low00aromatic ketone
7-[(4-acetylphenoxy)methyl]-5-thiazolo[3,2-a]pyrimidinone[no description available]low00aromatic ketone
(3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinyl)-(2-chlorophenyl)methanone[no description available]low00aromatic ketone
1-[4-[(2-bromophenyl)-oxomethyl]-1H-pyrrol-2-yl]-2,2,2-trichloroethanone[no description available]low00aromatic ketone
2-(4-hydroxy-1,3-thiazol-2-yl)-1-phenylethan-1-one[no description available]low00aromatic ketone
N-[1-(4-methyl-6-oxo-1-pyrimidinyl)-2-oxo-2-phenylethyl]benzamide[no description available]low00aromatic ketone
N-[5-ethyl-3-[(4-methoxyphenyl)-oxomethyl]-2-thiophenyl]-2-(4-methyl-1-piperazinyl)acetamide[no description available]low00aromatic ketone
4-[[5-ethyl-3-[(4-methoxyphenyl)-oxomethyl]-2-thiophenyl]amino]-4-oxobutanoic acid[no description available]low00aromatic ketone
(2-anilino-4-methyl-1,3-thiazol-5-yl)(4-methoxyphenyl)methanone[no description available]low00aromatic ketone
(4-chlorophenyl)-[6,7-dichloro-4-[(dimethylamino)methyl]-5-hydroxy-2-methyl-3-benzofuranyl]methanone[no description available]low00aromatic ketone
cid 2858522[no description available]low00aromatic ketone
1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-5-ylthio)ethanone[no description available]low00aromatic ketone
2-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]-1-phenylethanone[no description available]low00aromatic ketone
(3-amino-5-nitro-2-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
2-nitrobenzoic acid [1-(4-methylphenyl)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
3-hydroxy-3-[2-oxo-2-[4-(1-pyrrolyl)phenyl]ethyl]-1H-indol-2-one[no description available]low00aromatic ketone
1-[4-[3-[4-(4-fluorophenyl)-1-piperazinyl]-2-hydroxypropoxy]phenyl]-1-propanone[no description available]low00aromatic ketone
1-[4-[4-[[6-bromo-2-(3-pyridinyl)-4-quinolinyl]-oxomethyl]-1-piperazinyl]phenyl]ethanone[no description available]low00aromatic ketone
N-[4-[(3-acetylphenyl)sulfamoyl]phenyl]-1-piperidinecarboxamide[no description available]low00aromatic ketone
(2,5-dimethylphenyl)-(6-methyl-5-imidazo[2,1-b]thiazolyl)methanone[no description available]low00aromatic ketone
3-hydroxy-1-adamantanecarboxylic acid [2-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester[no description available]low00aromatic ketone
[2-[(2,6-dimethyl-4-morpholinyl)-oxomethyl]phenyl]-(1H-imidazol-2-yl)methanone[no description available]low00aromatic ketone
3-(2-furanyl)-3-oxo-2-(2-pyridinyl)propanenitrile[no description available]low00aromatic ketone
1-[4-ethoxy-3-[[[4-(2-oxolanylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]methyl]phenyl]ethanone[no description available]low00aromatic ketone
timiperone[no description available]low00aromatic ketone
adefovir[no description available]low00aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
organooxygen heterocyclic antibiotic;
polyphenol		antimalarial;
Aspergillus metabolite;
marine metabolite
phenyl-(2-thiophen-2-yl-5,10b-dihydro-1H-pyrazolo[1,5-c][1,3]benzoxazin-5-yl)methanone[no description available]low00aromatic ketone
N-[3-[(4-chlorophenyl)-oxomethyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-3-pyridinecarboxamide[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[(4-methyl-1,2,4-triazol-3-yl)thio]ethanone[no description available]low00aromatic ketone
2-quinolinecarboxylic acid (1-oxo-1-phenylpropan-2-yl) ester[no description available]low00aromatic ketone
N-(3-acetylphenyl)-3-(1-ethyl-3-methyl-4-pyrazolyl)-4,5-dihydroisoxazole-5-carboxamide[no description available]low00aromatic ketone
1-[4-[4-[[1-(4-chlorophenyl)sulfonylcyclopropyl]-oxomethyl]-1-piperazinyl]phenyl]ethanone[no description available]low00aromatic ketone
1-[2-(4-bromophenyl)-2-oxoethyl]-3-(2-furanylmethyl)-6,7-dimethoxyquinazoline-2,4-dione[no description available]low00aromatic ketone
N-(3-acetylphenyl)-3,5-dimethyl-4-isoxazolesulfonamide[no description available]low00aromatic ketone
3-[4-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-3-oxo-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid[no description available]low00aromatic ketone
3-[(3-fluorophenyl)methyl]-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one[no description available]low00aromatic ketone
4-[(4-acetyl-2-methoxyphenyl)methoxy]-3-methoxybenzoic acid [1-(carbamoylamino)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
N-(2-chloro-3-pyridinyl)-3-oxo-3-phenylpropanamide[no description available]low00aromatic ketone
5-[2-(4-bromophenyl)-2-oxoethyl]-1,3-diphenyl-2-sulfanylidene-4-imidazolidinone[no description available]low00aromatic ketone
2-(thiophen-2-ylsulfonylamino)benzoic acid [2-(3-acetylanilino)-2-oxo-1-phenylethyl] ester[no description available]low00aromatic ketone
4-(4-chlorophenyl)-N-[3-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-oxobutanamide[no description available]low00aromatic ketone
2-[4-[oxo(thiophen-2-yl)methyl]phenyl]propanoic acid methyl ester[no description available]low00aromatic ketone
N-[3-[(3-chlorophenyl)sulfamoyl]-4-methylphenyl]-3-(4-nitrophenyl)-3-oxopropanamide[no description available]low00aromatic ketone
rs 102221[no description available]low00aromatic ketone
N-[2-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-4-oxo-3-quinazolinyl]benzamide[no description available]low00aromatic ketone
3-methyl-2-methylene-1,5-diphenylpentane-1,5-dione[no description available]low00aromatic ketone
2-[1-(2-methylphenyl)-3-oxo-3-thiophen-2-ylpropyl]propanedinitrile[no description available]low00aromatic ketone
(4-chlorophenyl)-(7-methyl-3-imidazo[1,2-a]pyridinyl)methanone[no description available]low00aromatic ketone
2-[(4-hydroxy-3-nitrophenyl)sulfonylamino]benzoic acid [2-(4-methoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
4-benzoyl-2-heptyl-5-methyl-4H-pyrazol-3-one[no description available]low00aromatic ketone
(4-benzoyl-1-methyl-3-pyrrolidinyl)-phenylmethanone[no description available]low00aromatic ketone
6-benzoyl-2-phenyl-5-(trifluoromethyl)-3-pyridazinone[no description available]low00aromatic ketone
LY-310762[no description available]low00aromatic ketone;
monofluorobenzenes;
oxindoles;
piperidines;
tertiary amino compound		receptor modulator;
serotonergic antagonist
1-(4-methylphenyl)-2-[(1-phenyl-2-imidazolyl)thio]ethanone[no description available]low00aromatic ketone
gr 103691[no description available]low00aromatic ketone
4-(1,3-dioxo-2-benzo[de]isoquinolinyl)butanoic acid [2-(2-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-chloro-N-(2,6-dimethylphenyl)-3-oxo-3-phenylpropanamide[no description available]low00aromatic ketone
1-(4-chlorophenyl)-2-[[3-(3-methylphenyl)-1,2,4-thiadiazol-5-yl]thio]ethanone[no description available]low00aromatic ketone
N-(3-acetylphenyl)-2-[[6-chloro-3-(2-hydroxypropyl)-4-methyl-2-oxo-1-benzopyran-7-yl]oxy]acetamide[no description available]low00aromatic ketone
4-[4-(4-acetylphenyl)-1-piperazinyl]-N-[3-(dimethylamino)propyl]-3-nitrobenzenesulfonamide[no description available]low00aromatic ketone
2-chloro-1-[1-(3-isoxazolyl)-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
5-[(5-bromo-2-hydroxyphenyl)-oxomethyl]-1-cyclohexyl-2-oxo-3-pyridinecarbonitrile[no description available]low00aromatic ketone
2-[(5-ethyl-2-thiophenyl)-oxomethyl]benzoic acid[no description available]low00aromatic ketone
3-[4-(4-morpholinylsulfonyl)phenyl]propanoic acid [2-(4-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
rottlerin[no description available]low00aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite
isoegomaketone[no description available]low00aromatic ketone
palbociclib[no description available]low00aminopyridine;
aromatic ketone;
cyclopentanes;
piperidines;
pyridopyrimidine;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
radicinin[no description available]low00aromatic ketone
oxyfedrine[no description available]low00aromatic ketone
3-(dimethylamino)-1-(5-methyl-3-phenyl-4-isoxazolyl)-2-propen-1-one[no description available]low00aromatic ketone
2-[[5,6-bis(2-furanyl)-1,2,4-triazin-3-yl]thio]-1-(4-methoxyphenyl)ethanone[no description available]low00aromatic ketone
buflomedil hydrochloride[no description available]low00aromatic ketone
ciproxifan[no description available]low00aromatic ketone
4'-methyl-alpha-pyrrolidinopropiophenone[no description available]low00aromatic ketone
l-165041[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]acetamide[no description available]low00aromatic ketone
N-[4-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]phenyl]acetamide[no description available]low00aromatic ketone
6-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-3,4-dihydro-1H-quinolin-2-one[no description available]low00aromatic ketone
2-(2-benzoyl-1-pyrrolyl)-N-methyl-N-(phenylmethyl)acetamide[no description available]low00aromatic ketone
ic 86621[no description available]low00aromatic ketone
scio-469[no description available]low00aromatic amide;
aromatic ketone;
chloroindole;
dicarboxylic acid diamide;
indolecarboxamide;
monofluorobenzenes;
N-acylpiperazine;
N-alkylpiperazine		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
am 694[no description available]low00aromatic ketone;
indoles;
organofluorine compound;
organoiodine compound;
synthetic cannabinoid		cannabinoid receptor agonist
fonsecinone a[no description available]low00aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
polyphenol		antibacterial agent;
Aspergillus metabolite
e 5555[no description available]low00aromatic ketone
cytosporone b[no description available]low00aromatic ketone
benzobicyclon[no description available]low00aromatic ketone;
carbobicyclic compound;
cyclic ketone;
monochlorobenzenes;
organic sulfide;
sulfone
tembotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclic ketone;
ether;
monochlorobenzenes;
organofluorine compound;
sulfone		agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
y134 compound[no description available]low00aromatic ketone
N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(4-ethoxyphenyl)-2,4-dioxobutanamide[no description available]low00aromatic ketone
[9-(benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone[no description available]low00aromatic ketone;
quinolines
alpha(-(cyclopropylcarbonyl)-2-(methyvlsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile)[no description available]low00(trifluoromethyl)benzenes;
aromatic ketone;
beta-diketone;
cyclopropanes;
nitrile;
sulfone		agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
aflatoxin m1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone;
tertiary alcohol		Aspergillus metabolite;
human xenobiotic metabolite;
mammalian metabolite
acetic acid [4-[[(3aS,4R,9aS,9bR)-2-(2-naphthalenyl)-1,3-dioxo-3a,4,9a,9b-tetrahydropyrrolo[1,2]pyrrolo[3,5-b]pyridazin-4-yl]-oxomethyl]phenyl] ester[no description available]low00aromatic ketone
(3R,3aR,7aR)-3-[4-(4-acetylphenyl)-2-fluorophenyl]-7a-methyl-2-(phenylmethyl)-3,3a,6,7-tetrahydroisoindol-1-one[no description available]low00aromatic ketone
(3-propan-2-yloxyphenyl)-[1-[(1-propan-2-yl-4-pyrazolyl)methyl]-3-piperidinyl]methanone[no description available]low00aromatic ketone
[2-(methylthio)phenyl]-[1-[oxo(4-thiadiazolyl)methyl]-3-piperidinyl]methanone[no description available]low00aromatic ketone
2-(3,5-dimethyl-1-pyrazolyl)-1-[3-[oxo-(3-propan-2-yloxyphenyl)methyl]-1-piperidinyl]ethanone[no description available]low00aromatic ketone
[1-[(5-methyl-1-propyl-4-pyrazolyl)methyl]-3-piperidinyl]-(3-propan-2-yloxyphenyl)methanone[no description available]low00aromatic ketone
[1-[[1-(5-chloro-2-pyridinyl)-2-pyrrolyl]methyl]-3-piperidinyl]-(2,4-dimethoxyphenyl)methanone[no description available]low00aromatic ketone
2-(2-acetyl-3,5-dihydroxyphenyl)acetic acid[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone[no description available]low00aromatic ketone;
catechols;
thiocyanates
(3R,3aS,7R,7aS)-3-[3-(4-acetylphenyl)-4-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one[no description available]low00aromatic ketone
N-(3-acetylphenyl)-5-(3-methyl-5-isoxazolyl)-2-thiophenesulfonamide[no description available]low00aromatic ketone
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-1,3-dihydroindol-2-one[no description available]low00aromatic ketone
plx 4720[no description available]low00aromatic ketone;
difluorobenzene;
organochlorine compound;
pyrrolopyridine;
sulfonamide		antineoplastic agent;
B-Raf inhibitor
lcl161[no description available]low001,3-thiazoles;
aromatic ketone;
L-alanine derivative;
monofluorobenzenes;
N-acylpyrrolidine		antineoplastic agent;
apoptosis inducer
a-922500[no description available]low00aromatic ketone
marinopyrrole a[no description available]low00aromatic ketone;
organochlorine compound;
phenols;
pyrroles		antibacterial agent;
antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
marine metabolite
plx4032[no description available]low00aromatic ketone;
difluorobenzene;
monochlorobenzenes;
pyrrolopyridine;
sulfonamide		antineoplastic agent;
B-Raf inhibitor
1-[2-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone[no description available]low00aromatic ketone;
thienopyrimidine
cblc137[no description available]low00aromatic ketone;
carbazoles;
methyl ketone;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
NF-kappaB inhibitor;
p53 activator
myrtucommulone a[no description available]low00aromatic ketone
(3,4-dimethoxyphenyl)-[1-(2-phenylethyl)-3-piperidinyl]methanone[no description available]low00aromatic ketone
[1-(cyclohexylmethyl)-3-piperidinyl]-(3,4-dimethoxyphenyl)methanone[no description available]low00aromatic ketone
yk 4-279[no description available]low00aromatic ketone
1-[3-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone[no description available]low00aromatic ketone;
thienopyrimidine
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-3,3-dichloro-1H-indol-2-one[no description available]low00aromatic ketone
mephedrone[no description available]low00amphetamines;
aromatic ketone;
secondary amino compound		environmental contaminant;
xenobiotic
alectinib[no description available]low00aromatic ketone;
morpholines;
nitrile;
organic heterotetracyclic compound;
piperidines		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
4-methylethcathinone[no description available]low00aromatic ketone
3,4-dimethylmethcathinone[no description available]low00aromatic ketone
pogostone[no description available]low00aromatic ketone
ilicicolin h[no description available]low00aromatic ketone;
carbobicyclic compound;
ilicicolin;
monohydroxypyridine;
octahydronaphthalenes;
phenols;
pyridone		antimicrobial agent;
mitochondrial respiratory-chain inhibitor
[4-amino-2-[2-methoxy-4-(4-methyl-1-piperazinyl)anilino]-5-thiazolyl]-(2,6-dichlorophenyl)methanone[no description available]low00aromatic ketone
biliatresone[no description available]low00aromatic ether;
aromatic ketone;
benzodioxoles;
enone;
phenols		plant metabolite;
toxin
myxopyronin b[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[(4-oxo-1H-quinazolin-2-yl)thio]butanamide[no description available]low00aromatic ketone
6-amino-2-[[2-(3,4-dimethylphenyl)-2-oxoethyl]thio]-1H-pyrimidin-4-one[no description available]low00aromatic ketone
3-(4-oxo-1H-quinazolin-2-yl)propanoic acid [1-(4-bromophenyl)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
nbi 31772[no description available]low00aromatic ketone;
benzenediols;
hydroxy monocarboxylic acid;
isoquinolines;
tetrol		insulin-like growth factor-binding protein inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
Abnormalities, Autosome0low10
Abnormalities, Chromosomal0low10
Abnormalities, Chromosome0low10
Abnormalities, Drug-Induced0low10
Acne0low10
Acne Vulgaris0low10
Actinic Reticuloid Syndrome0low10
Autosome Abnormalities0low10
Body Weight0low20
Brain Ischemia0low10
Cadaver0low10
Cancer of Liver0low10
Cancer of Lung0low10
Cancer of Stomach0low10
Cancer of the Liver0low10
Cancer of the Lung0low10
Cancer of the Stomach0low10
Cancer, Hepatocellular0low10
Carcinoma, Ehrlich Tumor0low10
Carcinoma, Hepatocellular0low20
Cerebral Ischemia0low10
Chromosomal Aberrations0low10
Chromosome Aberrations0low10
Chromosome Abnormalities0low10
Chronic Actinic Dermatitis0low10
Contact Dermatitis0low10
Corpse0low10
Cytogenetic Aberrations0low10
Cytogenetic Abnormalities0low10
Dermatitis Venenata0low10
Dermatitis, Actinic0low10
Dermatitis, Contact0low10
Disease Models, Animal0low10
Diseases of Endocrine System0low10
Drug-Induced Abnormalities0low10
Eczema, Contact0low10
Ehrlich Ascites Tumor0low10
Encephalopathy, Ischemic0low10
Endocrine Diseases0low10
Endocrine System Diseases0low10
Female Genital Diseases0low10
Fibrosarcoma0low10
Gastric Cancer0low10
Gastric Cancer, Familial Diffuse0low10
Gastric Neoplasms0low10
Genital Diseases, Female0low10
Germinoblastoma0low10
Gynecologic Diseases0low10
Hepatic Cancer0low10
Hepatic Neoplasms0low10
Hepatocellular Cancer0low10
Hepatocellular Carcinoma0low20
Hepatoma0low20
Hirsutism0low10
Hypersensitivity, Contact0low10
Injuries, Spinal Cord0low10
Ischemia, Cerebral0low10
Ischemic Encephalopathy0low10
Leukemia L51780low10
Liver Cancer0low10
Liver Cancer, Adult0low20
Liver Cell Carcinoma0low20
Liver Cell Carcinoma, Adult0low20
Liver Neoplasms0low10
Lung Cancer0low10
Lung Neoplasms0low10
Lymphoma0low10
Lymphoma L51780low10
Lymphoma, Malignant0low10
Myelopathy, Traumatic0low10
Neoplasms, Gastric0low10
Neoplasms, Hepatic0low10
Neoplasms, Liver0low10
Neoplasms, Lung0low10
Neoplasms, Pulmonary0low10
Neoplasms, Stomach0low10
Photodermatitis0low10
Photosensitivity Disorders0low10
Photosensitization0low10
Post-Traumatic Myelopathy0low10
Pregnancy0low20
Premenstrual Syndrome0low10
Premenstrual Tension0low10
Pulmonary Cancer0low10
Pulmonary Neoplasms0low10
Reticulolymphosarcoma0low10
Sarcoma, Germinoblastic0low10
Sensitivity and Specificity0low40
Sensitivity, Contact0low10
Spinal Cord Contusion0low10
Spinal Cord Injuries0low10
Spinal Cord Laceration0low10
Spinal Cord Transection0low10
Spinal Cord Trauma0low10
Stomach Cancer0low10
Stomach Neoplasms0low10

Research Highlights

Safety/Toxicity (9)

ArticleYear
Synthetic musk in seafood products from south Europe using a quick, easy, cheap, effective, rugged and safe extraction method.
Food chemistry, Jun-01, Volume: 200		2016
Comparison of embryo toxicity using two classes of aquatic vertebrates.
Environmental toxicology and pharmacology, Volume: 37, Issue: 1		2014
Read-across estimates of aquatic toxicity for selected fragrances.
Alternatives to laboratory animals : ATLA, Volume: 41, Issue: 1		2013
[Toxic effect of musk ketone based on the determinations of wheat (Triticum aestivum) seed germination and root elongation].
Ying yong sheng tai xue bao = The journal of applied ecology, Volume: 19, Issue: 6		2008
Developmental toxicity studies of four fragrances in rats.
Toxicology letters, Dec-20, Volume: 111, Issue: 1-2		1999
Toxicity of nitromusks in early lifestages of South African clawed frog (Xenopus laevis) and zebrafish (Danio rerio).
Toxicology letters, Dec-20, Volume: 111, Issue: 1-2		1999
Genotoxicity of nitro musks in the micronucleus test with human lymphocytes in vitro and the human hepatoma cell line Hep G2.
Toxicology letters, Mar-14, Volume: 91, Issue: 1		1997
An evaluation of genotoxicity tests with Musk ketone.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Volume: 34, Issue: 7		1996
A comparative study of five nitro musk compounds for genotoxicity in the SOS chromotest and Salmonella mutagenicity.
Toxicology letters, Volume: 85, Issue: 3		1996
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (2)

ArticleYear
Determination of polycyclic and nitro musks in environmental water samples by means of microextraction by packed sorbents coupled to large volume injection-gas chromatography-mass spectrometry analysis.
Analytica chimica acta, Apr-22, Volume: 773		2013
Stir-bar-sorptive extraction and liquid desorption combined with large-volume injection gas chromatography-mass spectrometry for ultra-trace analysis of musk compounds in environmental water matrices.
Analytical and bioanalytical chemistry, Volume: 396, Issue: 5		2010
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (1)

ArticleYear
In vitro determination of transdermal permeation of synthetic musks and estimated dermal uptake through usage of personal care products.
Chemosphere, Volume: 173		2017
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (7)

ArticleYear
Identification of bound nitro musk-protein adducts in fish liver by gas chromatography-mass spectrometry: biotransformation, dose-response and toxicokinetics of nitro musk metabolites protein adducts in trout liver as biomarkers of exposure.
Aquatic toxicology (Amsterdam, Netherlands), Jan-15, Volume: 106-107		2012
Biological transformation, kinetics and dose-response assessments of bound musk ketone hemoglobin adducts in rainbow trout as biomarkers of environmental exposure.
Journal of environmental sciences (China), Volume: 20, Issue: 7		2008
An in vivo mouse micronucleus assay on musk ketone.
Mutation research, Jan-24, Volume: 464, Issue: 2		2000
Developmental toxicity studies of four fragrances in rats.
Toxicology letters, Dec-20, Volume: 111, Issue: 1-2		1999
Effects of musk xylene and musk ketone on rat hepatic cytochrome P450 enzymes.
Toxicology letters, Dec-20, Volume: 111, Issue: 1-2		1999
Dermal absorption and disposition of musk ambrette, musk ketone and musk xylene in rats.
Toxicology letters, Dec-20, Volume: 111, Issue: 1-2		1999
Characterization of the effects of musk ketone on mouse hepatic cytochrome P450 enzymes.
Fundamental and applied toxicology : official journal of the Society of Toxicology, Volume: 40, Issue: 2		1997
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]