Page last updated: 2024-12-05
1,3,5-tribromobenzene
## 1,3,5-Tribromobenzene: A Building Block for Research
**1,3,5-tribromobenzene** is an organic compound with the formula C6H3Br3. It is a white solid at room temperature with a characteristic odor. Its structure consists of a benzene ring with three bromine atoms attached at the 1st, 3rd, and 5th positions.
**Why is it important for research?**
1,3,5-tribromobenzene serves as a **versatile building block** in various fields of research, including:
* **Organic synthesis:** It is a precursor for synthesizing various organic compounds. Its highly reactive bromine atoms can be substituted with other functional groups through nucleophilic aromatic substitution reactions, allowing for the creation of a wide array of new molecules.
* **Materials science:** It plays a role in the development of new materials with tailored properties. Its rigid structure and the presence of bromine atoms can contribute to the formation of crystalline materials with specific optical or electronic properties.
* **Medicinal chemistry:** 1,3,5-tribromobenzene can be used as a starting material in the synthesis of potential drug candidates. The bromine atoms can be modified to create new compounds with desired biological activities.
* **Analytical chemistry:** It is used as a reference standard in analytical techniques like gas chromatography-mass spectrometry (GC-MS) and high-performance liquid chromatography (HPLC).
* **Environmental chemistry:** It can be used as a model compound for studying the fate and transport of brominated organic pollutants in the environment.
**Specific examples of its applications:**
* **Synthesis of polybrominated diphenyl ethers (PBDEs):** These compounds are widely used as flame retardants, but some are considered environmentally hazardous. Studying the synthesis of PBDEs from 1,3,5-tribromobenzene can provide insights into their environmental impact.
* **Development of new materials with photoluminescent properties:** Researchers have used 1,3,5-tribromobenzene to synthesize materials exhibiting photoluminescence, potentially useful in optical devices and sensors.
* **Synthesis of novel drugs for treating cancer:** 1,3,5-tribromobenzene has been incorporated into the synthesis of several potential anticancer drugs, demonstrating its potential in the fight against cancer.
In conclusion, 1,3,5-tribromobenzene is an essential reagent for research in various fields, serving as a versatile building block for synthesizing new molecules with potentially valuable applications in organic synthesis, materials science, medicinal chemistry, and environmental chemistry.
Cross-References
ID Source | ID |
PubMed CID | 12279 |
SCHEMBL ID | 24617 |
MeSH ID | M0155943 |
Synonyms (37)
Synonym |
o3td0u1oaq , |
unii-o3td0u1oaq |
AKOS009031625 |
EN300-20007 |
1,3,5-tribromo-benzene |
1,3,5-tribromobenzene |
benzene, 1,3,5-tribromo- |
inchi=1/c6h3br3/c7-4-1-5(8)3-6(9)2-4/h1-3 |
1,5-tribromobenzene |
benzene,3,5-tribromo- |
nsc62439 |
626-39-1 |
nsc-62439 |
ai3-15483 |
einecs 210-947-3 |
nsc 62439 |
1,3,5-tribromobenzene, 98% |
NCIOPEN2_008123 |
T0347 |
A833903 |
AM20061088 |
CX1334 |
SCHEMBL24617 |
1,3,5-tribromobezene |
tox21_303951 |
dtxcid0030879 |
dtxsid3052307 , |
NCGC00357185-01 |
cas-626-39-1 |
W-104975 |
1,3,5-tribromobenzene, purum, >=98.0% (at) |
mfcd00000080 |
GS-3046 |
1,3,5-tribromobenzene; nsc 62439 |
SY006267 |
Q27285289 |
CS-0019382 |
Protein Targets (2)
Potency Measurements
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 1 (20.00) | 18.7374 |
1990's | 1 (20.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 40.98
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 40.98 (24.57) | Research Supply Index | 1.79 (2.92) | Research Growth Index | 4.54 (4.65) | Search Engine Demand Index | 56.46 (26.88) | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |