Page last updated: 2024-12-06

nicotinoyl-gaba

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

nicotinoyl-GABA: used in treatment of migraine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID60608
CHEMBL ID4303255
SCHEMBL ID678984
MeSH IDM0130869

Synonyms (65)

Synonym
34562-97-5
AC-19324
BB 0258436
pikamilone
picamilon
CBKINASE1_003003
EU-0052131
CBKINASE1_015403
gaba-ng
pikamilon
butanoic acid, 4-((3-pyridinylcarbonyl)amino)-
nicotinoyl-gaba
4-(pyridine-3-carbonylamino)butanoic acid
STK760083
AKOS000126425
n-(3-carboxypropyl)nicotinamide
4-[(pyridin-3-ylcarbonyl)amino]butanoic acid
4-(pyridine-3-carbonylamino)butanoic acid;pikamilone
A822275
0s5n9sek4n ,
unii-0s5n9sek4n
FT-0639198
4-(nicotinamido)butanoic acid
3-[(3-carboxypropyl)carbamoyl]pyridine
S5363
n-nicotinoyl-gamma-aminobutyric acid
4[(pyridine-3-carbonyl)-amino]-butyric acid
NAJVRARAUNYNDX-UHFFFAOYSA-N
SCHEMBL678984
mfcd00186518
4-nicotinoylamino-butyric acid
4-[(pyridine-3-carbonyl)amino]butyric acid
pycamilon
pikatropin
nicotinoyl-.gamma.-aminobutyric acid
W-202413
N0998
4-(nicotinamido)butyric acid
n-nicotinoyl-gaba
sr-01000523993
butanoic acid, 4-[(3-pyridinylcarbonyl)amino]-
DTXSID40188098
4-[(pyridin-3-yl)formamido]butanoic acid
AC-33105
1h-pyrazole, 1-(2-methylpropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
4-[(3-pyridinylcarbonyl)amino]butanoic acid
Z235541930
SR-01000523993-1
3-((3-carboxypropyl)carbamoyl)pyridine
BCP19066
Q4362563
AS-14847
HMS3886A04
CCG-266641
CHEMBL4303255
nicotinoyl-gaba; nicotinoyl-gamma-aminobutyric acid
nicotinoyl-gaba (sodium); nicotinoyl-gamma-aminobutyric acid (sodium)
pikamilone (sodium)
D70208
nicotinoyl-gaba; nicotinoyl--aminobutyric acid
EN300-113400
nicotinoyl-gaba (sodium); nicotinoyl--aminobutyric acid (sodium)
SB77795
CS-0028604
SY050468

Research Excerpts

Compound-Compound Interactions

ExcerptReferenceRelevance
"Electric impedance measurements on awake rabbits with electrodes implanted into cortex, thalamus, and hypothalamus showed that modeling of the noise and general (wide-band) vibration, as well as their combination with sea-sickness action, leads to disturbances in the aqueous-electrolyte balance in brain."( [Effects of pikamilon on the brain water-electrolyte balance and in models of responses to the noise and vibration exposure, and their combination with motion sickness].
Sapegin, ID,
)
0.13

Bioavailability

ExcerptReferenceRelevance
" The drug bioavailability at oral administration to mice is 21."( [Pikamilon pharmacokinetics in animals].
Dorofeev, BF; Kholodov, LE,
)
0.13
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (22.22)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's2 (22.22)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.90

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.90 (24.57)
Research Supply Index3.76 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index44.85 (26.88)
Search Engine Supply Index4.00 (0.95)

This Compound (21.90)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials4 (10.53%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other34 (89.47%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]