Page last updated: 2024-12-06

1,8-naphthalenedicarboxylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,8-naphthalenedicarboxylic acid is a white solid that is sparingly soluble in water. It is a dicarboxylic acid that can be synthesized by the oxidation of 1,8-dimethylnaphthalene. 1,8-naphthalenedicarboxylic acid is used as a precursor to polymers and as a starting material for the synthesis of other organic compounds. It is also a potential building block for the construction of functionalized materials. The compound has been studied for its potential applications in organic electronics and as a catalyst for organic reactions. It exhibits fluorescence and is under investigation for its potential use in fluorescent probes and sensors.'

1,8-naphthalenedicarboxylic acid: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID68204
SCHEMBL ID68291
MeSH IDM0198114

Synonyms (30)

Synonym
1,8-naphthalic acid
nsc37065
518-05-8
naphthalic acid
1,8-naphthalenedicarboxylic acid
nsc-37065
NCI60_008003
AE-641/05536032
SR-01000645150-1
AC-10622
AKOS000278046
HMS1661D04
naphthalene-1,8-dicarboxylic acid
einecs 208-247-8
u1t26yew8c ,
unii-u1t26yew8c
nsc 37065
STK525477
A828792
CCG-56176
naphthalic acid [mi]
SCHEMBL68291
naphthalsaure
HRRDCWDFRIJIQZ-UHFFFAOYSA-N
1,8-naphthalicacid
bio1g11
DTXSID90199730
FT-0727282
Q27290570
CS-0368272
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's4 (40.00)24.3611
2020's1 (10.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.85

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.85 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.62 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.85)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]