bupivacaine has been researched along with Sensitivity and Specificity in 52 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypotension is a common side effect associated with spinal anesthesia." | 6.70 | Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine. ( Charuluxananan, S; Kyokong, O; Leerapun, R; Pothimamaka, S, 2001) |
| "Postoperative pain was assessed and recorded using the visual analog scale (VAS) at postoperative hours 1, 2, 3, 4, 5, 6, 7, 8, 12, 16, 20, 24, and 48." | 2.73 | Periprostatic nerve blockage reduces postoperative analgesic consumption and pain scores of patients undergoing transurethral prostate resection. ( Akkurt, BC; Candan, Y; Gorur, S; Inanoglu, K; Kiper, AN, 2007) |
| "Hypotension is a common side effect associated with spinal anesthesia." | 2.70 | Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine. ( Charuluxananan, S; Kyokong, O; Leerapun, R; Pothimamaka, S, 2001) |
| " The optimized methods show good linearity, precision (RSD < 2%) and accuracy (bias < 2% for dosage forms)." | 1.29 | Validation of high-performance liquid chromatographic methods on two silica base-deactivated reversed phases for the determination of chloroprocaine and bupivacaine. ( Brun, F; Veuthey, JL, 1996) |
| "Sensitivity and specificity were 50% and 97%, respectively." | 1.29 | Factors associated with hypotension and bradycardia after epidural blockade. ( Curatolo, M; Orlando, A; Scaramozzino, P; Venuti, FS; Zbinden, AM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (30.77) | 18.2507 |
| 2000's | 25 (48.08) | 29.6817 |
| 2010's | 10 (19.23) | 24.3611 |
| 2020's | 1 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Kesici, S | 1 |
| Demirci, M | 1 |
| Kesici, U | 1 |
| Istenič, S | 1 |
| Cvetko, E | 1 |
| Zabret, J | 1 |
| Stopar Pintarič, T | 1 |
| Umek, N | 1 |
| Cho, SH | 1 |
| Park, JA | 1 |
| Zheng, W | 1 |
| Abd El-Aty, AM | 1 |
| Kim, SK | 1 |
| Choi, JM | 1 |
| Yi, H | 1 |
| Cho, SM | 1 |
| Afifi, NA | 1 |
| Shim, JH | 1 |
| Chang, BJ | 1 |
| Kim, JS | 1 |
| Shin, HC | 1 |
| del Mar LópezGuerrero, M | 1 |
| Hernández-Mesa, M | 1 |
| Cruces-Blanco, C | 1 |
| García-Campaña, AM | 1 |
| Altun, Z | 1 |
| Abdel-Rehim, M | 2 |
| Elsayed, MM | 1 |
| Vierl, U | 1 |
| Cevc, G | 1 |
| Salmerón-García, A | 1 |
| Navas, N | 1 |
| Martín, A | 1 |
| Román, E | 1 |
| Cabeza, J | 1 |
| Capitán-Vallvey, LF | 1 |
| Chang, YW | 1 |
| Liao, CH | 1 |
| Day, YJ | 1 |
| Wetmore, BA | 1 |
| Brees, DJ | 1 |
| Singh, R | 1 |
| Watkins, PB | 1 |
| Andersen, ME | 1 |
| Loy, J | 1 |
| Thomas, RS | 1 |
| Qin, WW | 1 |
| Jiao, Z | 1 |
| Zhong, MK | 1 |
| Shi, XJ | 1 |
| Zhang, J | 1 |
| Li, ZD | 1 |
| Cui, XY | 1 |
| Onnerud, H | 1 |
| Bassiouny, F | 1 |
| Kretzschmar, M | 1 |
| Wiewiorski, M | 1 |
| Rasch, H | 1 |
| Jacob, AL | 1 |
| Bilecen, D | 1 |
| Walter, MA | 1 |
| Valderrabano, V | 1 |
| Baker, JF | 1 |
| Walsh, PM | 1 |
| Byrne, DP | 1 |
| Mulhall, KJ | 1 |
| Rump, JC | 1 |
| Streitparth, F | 1 |
| Böning, G | 1 |
| Seebauer, CJ | 1 |
| Walter, T | 1 |
| Güttler, F | 1 |
| Hamm, B | 1 |
| Teichgräber, UK | 1 |
| Margarido, CB | 1 |
| Dlacic, A | 1 |
| Balki, M | 1 |
| Furtado, L | 1 |
| Carvalho, JC | 1 |
| Yuen, TS | 1 |
| Ng, KF | 1 |
| Tsui, SL | 1 |
| Henry, BJ | 1 |
| Kenison, M | 1 |
| McVay, C | 1 |
| Rolfe, R | 1 |
| Graham, S | 1 |
| Rasty, J | 1 |
| Slauterbeck, J | 1 |
| Dabezies, EJ | 1 |
| Faraj, AA | 1 |
| Kumaraguru, P | 1 |
| Kosygan, K | 1 |
| Emery, J | 1 |
| Ho, D | 1 |
| MacKeen, L | 1 |
| Héon, E | 1 |
| Bissonnette, B | 1 |
| Laslett, M | 1 |
| Oberg, B | 1 |
| Aprill, CN | 2 |
| McDonald, B | 1 |
| Filler, AG | 1 |
| Haynes, J | 1 |
| Jordan, SE | 1 |
| Prager, J | 1 |
| Villablanca, JP | 1 |
| Farahani, K | 1 |
| McBride, DQ | 1 |
| Tsuruda, JS | 1 |
| Morisoli, B | 1 |
| Batzdorf, U | 1 |
| Johnson, JP | 1 |
| Hoizey, G | 1 |
| Lamiable, D | 1 |
| Robinet, A | 1 |
| Ludot, H | 1 |
| Malinovsky, JM | 1 |
| Kaltenbach, ML | 1 |
| Binet, L | 1 |
| Boulanger, C | 1 |
| Millart, H | 1 |
| Sänger-van de Griend, CE | 1 |
| Ek, AG | 1 |
| Widahl-Näsman, ME | 1 |
| Andersson, EK | 1 |
| Wei, S | 1 |
| Guo, H | 1 |
| Lin, JM | 1 |
| Tanaka, E | 1 |
| Nakamura, T | 1 |
| Inomata, S | 1 |
| Honda, K | 1 |
| Schmid, MR | 1 |
| Kissling, RO | 1 |
| Curt, A | 1 |
| Jaschko, G | 1 |
| Hodler, J | 1 |
| Gorur, S | 1 |
| Inanoglu, K | 1 |
| Akkurt, BC | 1 |
| Candan, Y | 1 |
| Kiper, AN | 1 |
| Mahajan, R | 1 |
| Batra, YK | 1 |
| Kumar, S | 1 |
| Tiger, G | 1 |
| Lundin, D | 1 |
| Fowler, CJ | 1 |
| Schwarzer, AC | 1 |
| Derby, R | 1 |
| Fortin, J | 1 |
| Kine, G | 1 |
| Bogduk, N | 1 |
| Gupta, RN | 1 |
| Dauphin, A | 1 |
| Iossifidis, A | 1 |
| Brun, F | 1 |
| Veuthey, JL | 1 |
| Mizel, MS | 1 |
| Michelson, JD | 1 |
| Newberg, A | 1 |
| Curatolo, M | 1 |
| Scaramozzino, P | 1 |
| Venuti, FS | 1 |
| Orlando, A | 1 |
| Zbinden, AM | 1 |
| Siluveru, M | 1 |
| Stewart, JT | 1 |
| Crawford, RW | 1 |
| Gie, GA | 1 |
| Ling, RS | 1 |
| Murray, DW | 1 |
| De Wachter, DS | 1 |
| Verdonck, PR | 1 |
| Verhoeven, RF | 1 |
| Gu, XQ | 1 |
| Fryirs, B | 1 |
| Mather, LE | 1 |
| Reif, S | 1 |
| Le Corre, P | 1 |
| Dollo, G | 1 |
| Chevanne, F | 1 |
| Le Verge, R | 1 |
| Gross, AS | 1 |
| Nicolay, A | 1 |
| Eschalier, A | 1 |
| Arvidsson, T | 1 |
| Askemark, Y | 1 |
| Halldin, MM | 1 |
| Tsujiguchi, N | 1 |
| Fujita, S | 1 |
| Kawamata, T | 1 |
| Omote, K | 1 |
| Matsumoto, M | 1 |
| Namiki, A | 1 |
| Durkin, D | 1 |
| Foley, JP | 1 |
| Stringer, NH | 1 |
| Rodino, KL | 1 |
| Edwards, M | 1 |
| Kumari, NV | 1 |
| Stumpe, M | 1 |
| Morton, NS | 1 |
| Watson, DG | 1 |
| Ozgün, H | 1 |
| Cevikel, MH | 1 |
| Boylu, S | 1 |
| Kyokong, O | 1 |
| Charuluxananan, S | 1 |
| Pothimamaka, S | 1 |
| Leerapun, R | 1 |
| Hofmann-Kiefer, K | 1 |
| Herbrich, C | 1 |
| Seebauer, A | 1 |
| Schwender, D | 1 |
| Peter, K | 1 |
| Montanari, L | 1 |
| Cilurzo, F | 1 |
| Conti, B | 1 |
| Genta, I | 1 |
| Groppo, A | 1 |
| Valvo, L | 1 |
| Faucitano, A | 1 |
| Buttafava, A | 1 |
| Gieraerts, R | 1 |
| Van Zundert, A | 1 |
| De Wolf, A | 1 |
| Vaes, L | 1 |
| Kalso, E | 1 |
| Aromaa, U | 1 |
| Tammisto, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Spinal Morphine (0.05 mg) Provides an Effective Pain Control in Patients Undergoing Transurethral Resection of Prostate Gland- a Randomized Double-blinded Control Trial[NCT02458742] | 80 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 trials available for bupivacaine and Sensitivity and Specificity
| Article | Year |
|---|---|
99mTc-DPD-SPECT/CT predicts the outcome of imaging-guided diagnostic anaesthetic injections: a prospective cohort study.
Topics: Adult; Aged; Anesthetics, Local; Ankle Joint; Arthralgia; Bupivacaine; Cohort Studies; Diagnosis, Co | 2011 |
Intra-articular bupivacaine hip injection in differentiation of coxarthrosis from referred thigh pain: a 10 year study.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Arthroplasty, Replacement, Hip; Bupivacaine; Dia | 2003 |
Zygapophysial joint blocks in chronic low back pain: a test of Revel's model as a screening test.
Topics: Adult; Aged; Anesthetics, Local; Bupivacaine; Chronic Disease; Female; Humans; Injections, Intra-Art | 2004 |
Periprostatic nerve blockage reduces postoperative analgesic consumption and pain scores of patients undergoing transurethral prostate resection.
Topics: Aged; Anesthetics, Local; Bupivacaine; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; | 2007 |
Hypotension in spinal anesthesia for cesarean section: a comparison of 0.5% hyperbaric bupivacaine and 5% hyperbaric lidocaine.
Topics: Adult; Anesthesia, Spinal; Blood Pressure Determination; Bupivacaine; Cesarean Section; Chi-Square D | 2001 |
Ropivacaine 7.5 mg/ml versus bupivacaine 5 mg/ml for interscalene brachial plexus block--a comparative study.
Topics: Adult; Aged; Amides; Anesthesia, Conduction; Anesthesia, General; Anesthetics, Local; Brachial Plexu | 2002 |
Ten ml bupivacaine 0.125% with 12.5 micrograms epinephrine is a reliable epidural test dose to detect inadvertent intravascular injection in obstetric patients. A double-blind study.
Topics: Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthesia, Obstetrical; Apgar Sc | 1992 |
Sensitivity, specificity and predictive value of the sensation of warmth as a method of detecting inadvertent subarachnoid injection of local anaesthetic when performing extradural blocks.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Epidural; Bupivacaine; Female; Hot Temperature; Humans; | 1991 |
44 other studies available for bupivacaine and Sensitivity and Specificity
| Article | Year |
|---|---|
Bacterial inhibition efficiency of prilocaine and bupivacaine.
Topics: Bupivacaine; Escherichia coli; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Prilocaine; | 2019 |
Determination of bupivacaine tissue concentration in human biopsy samples using high-performance liquid chromatography with mass spectrometry.
Topics: Biopsy; Bupivacaine; Chromatography, High Pressure Liquid; Humans; Linear Models; Mass Spectrometry; | 2021 |
Quantification of bupivacaine hydrochloride and isoflupredone acetate residues in porcine muscle, beef, milk, egg, shrimp, flatfish, and eel using a simplified extraction method coupled with liquid chromatography-triple quadrupole tandem mass spectrometry
Topics: Animals; Bupivacaine; Chromatography, Liquid; Drug Residues; Eels; Flatfishes; Fluprednisolone; Line | 2017 |
On-line preconcentration strategy for the simultaneous quantification of three local anesthetics in human urine using CZE.
Topics: Anesthetics, Local; Bupivacaine; Electrophoresis, Capillary; Female; Humans; Lidocaine; Limit of Det | 2015 |
Study of the factors affecting the performance of microextraction by packed sorbent (MEPS) using liquid scintillation counter and liquid chromatography-tandem mass spectrometry.
Topics: Blood Chemical Analysis; Bupivacaine; Chromatography, High Pressure Liquid; Reproducibility of Resul | 2008 |
Accurate potentiometric determination of lipid membrane-water partition coefficients and apparent dissociation constants of ionizable drugs: electrostatic corrections.
Topics: Bupivacaine; Diclofenac; Ions; Ketoprofen; Membrane Lipids; Naphthalenes; Osmolar Concentration; Pha | 2009 |
Determination of tramadol, metamizole, ropivacaine, and bupivacaine in analgesic mixture samples by HPLC with DAD detection.
Topics: Amides; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; | 2009 |
Platelet function analyzer (PFA-100) offers higher sensitivity and specificity than thromboelastography (TEG) in detection of platelet dysfunction.
Topics: Adenosine; Bupivacaine; Dose-Response Relationship, Drug; Humans; Levobupivacaine; Phenethylamines; | 2009 |
Quantitative analyses and transcriptomic profiling of circulating messenger RNAs as biomarkers of rat liver injury.
Topics: Acetaminophen; Alanine Transaminase; Albumins; Analgesics, Non-Narcotic; Anesthetics, Local; Animals | 2010 |
Simultaneous determination of procaine, lidocaine, ropivacaine, tetracaine and bupivacaine in human plasma by high-performance liquid chromatography.
Topics: Amides; Bupivacaine; Chromatography, High Pressure Liquid; Drug Stability; Humans; Least-Squares Ana | 2010 |
Chromatographic behavior of bupivacaine and five of its major metabolites in human plasma, utilizing solid-phase extraction and capillary gas chromatography.
Topics: Bupivacaine; Drug Stability; Gas Chromatography-Mass Spectrometry; Humans; Linear Models; Reproducib | 2010 |
In vitro assessment of human chondrocyte viability after treatment with local anaesthetic, magnesium sulphate or normal saline.
Topics: Amides; Analysis of Variance; Anesthetics, Local; Bupivacaine; Cell Survival; Cells, Cultured; Chond | 2011 |
Evaluation of a MR-quadrupole imaging coil for spinal interventions in a vertical 1.0 T MRI.
Topics: Anesthetics, Local; Bupivacaine; Equipment Design; Equipment Failure Analysis; Humans; Image Enhance | 2012 |
The epidural electric stimulation test does not predict local anesthetic spread or consumption in labour epidural analgesia.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Anesthetics, Loca | 2013 |
Neurolytic celiac plexus block for visceral abdominal malignancy: is prior diagnostic block warranted?
Topics: Abdominal Neoplasms; Anesthetics, Local; Autonomic Nerve Block; Bupivacaine; Celiac Plexus; Ethanol; | 2002 |
The effect of local hematoma blocks on early fracture healing.
Topics: Analysis of Variance; Animals; Bupivacaine; Disease Models, Animal; Femoral Fractures; Fracture Fixa | 2002 |
Pupillary reflex dilation and skin temperature to assess sensory level during combined general and caudal anesthesia in children.
Topics: Analysis of Variance; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Combined; Anesthetics, I | 2004 |
Sciatica of nondisc origin and piriformis syndrome: diagnosis by magnetic resonance neurography and interventional magnetic resonance imaging with outcome study of resulting treatment.
Topics: Adult; Aged; Back; Bupivacaine; Diagnosis, Differential; Follow-Up Studies; Humans; Image Enhancemen | 2005 |
Sensitive bioassay of bupivacaine in human plasma by liquid-chromatography-ion trap mass spectrometry.
Topics: Acetonitriles; Amides; Anesthetics, Local; Biological Assay; Bupivacaine; Calibration; Chemistry, Ph | 2005 |
Method development for the enantiomeric purity determination of low concentrations of adrenaline in local anaesthetic solutions by capillary electrophoresis.
Topics: Anesthetics; Bupivacaine; Chemistry, Pharmaceutical; Cyclodextrins; Electrolytes; Electrophoresis, C | 2006 |
Chiral separation of salbutamol and bupivacaine by capillary electrophoresis using dual neutral cyclodextrins as selectors and its application to pharmaceutical preparations and rat blood samples assay.
Topics: Albuterol; Animals; Buffers; Bupivacaine; Cyclodextrins; Electrophoresis, Capillary; Hydrogen-Ion Co | 2006 |
Simultaneous determination of three local anesthetic drugs from the pipecoloxylidide group in human serum by high-performance liquid chromatography.
Topics: Amides; Anesthetics, Local; Bupivacaine; Chromatography, High Pressure Liquid; Humans; Mepivacaine; | 2006 |
Sympathetic skin response: monitoring of CT-guided lumbar sympathetic blocks.
Topics: Adolescent; Adult; Anesthesia, Spinal; Anesthetics, Local; Autonomic Nerve Block; Body Temperature; | 2006 |
Caudal 'Whoosh' or modified 'Swoosh': be careful to push.
Topics: Air; Anesthesia, Caudal; Anesthetics, Local; Auscultation; Blood Pressure; Bronchodilator Agents; Bu | 2008 |
Veratrine-stimulated phosphoinositide breakdown as an assay for local anesthetic actions at Na+ channels.
Topics: Anesthetics, Local; Animals; Bupivacaine; Drug Interactions; Hydrolysis; Male; Monensin; Ouabain; Ph | 1995 |
The value of the provocation response in lumbar zygapophyseal joint injections.
Topics: Adult; Bupivacaine; Female; Humans; Injections, Intra-Articular; Injections, Spinal; Lidocaine; Low | 1994 |
Column liquid chromatographic determination of bupivacaine in human serum using solid-phase extraction.
Topics: Acetonitriles; Bupivacaine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration | 1994 |
Knee arthroscopy under local anaesthesia: results and evaluation of patients' satisfaction.
Topics: Adolescent; Adult; Anesthetics, Local; Arthroscopy; Bupivacaine; Female; Humans; Knee Joint; Lidocai | 1996 |
Validation of high-performance liquid chromatographic methods on two silica base-deactivated reversed phases for the determination of chloroprocaine and bupivacaine.
Topics: Anesthetics, Local; Aniline Compounds; Bupivacaine; Chromatography, High Pressure Liquid; Drug Stabi | 1996 |
Peroneal tendon bupivacaine injection: utility of concomitant injection of contrast material.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Bupivacaine; Contrast Media; Drug Combinations; Female; | 1996 |
Factors associated with hypotension and bradycardia after epidural blockade.
Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; B | 1996 |
Stereoselective determination of R(-)- and S(+)-prilocaine in human serum using a brush-type chiral stationary phase, solid-phase extraction and UV detection.
Topics: Anesthetics, Local; Bupivacaine; Calibration; Chromatography, High Pressure Liquid; Humans; Prilocai | 1996 |
Diagnostic value of intra-articular anaesthetic in primary osteoarthritis of the hip.
Topics: Anesthetics, Local; Arthroplasty, Replacement, Hip; Bupivacaine; Female; Follow-Up Studies; Hip Join | 1998 |
Distribution of Marcaine in an in vitro model of the subarachnoid space conforming to actual spinal column geometries.
Topics: Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Equipment Design; Injections, Spinal; Models, A | 1997 |
High-performance liquid chromatographic separation and nanogram quantitation of bupivacaine enantiomers in blood.
Topics: Anesthetics, Local; Animals; Bupivacaine; Chromatography, High Pressure Liquid; Humans; Sensitivity | 1998 |
High-performance liquid chromatographic determination of ropivacaine, 3-hydroxy-ropivacaine, 4-hydroxy-ropivacaine and 2',6'-pipecoloxylidide in plasma.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Chromatography, High Pressure Liquid; Rabbits; Rop | 1998 |
Simultaneous analysis of ketamine and bupivacaine in plasma by high-performance liquid chromatography.
Topics: Bupivacaine; Child; Chromatography, High Pressure Liquid; Humans; Ketamine; Reference Standards; Rep | 1999 |
Liquid chromatographic bioanalytical determination of ropivacaine, bupivacaine and major metabolites.
Topics: Amides; Anesthetics, Local; Animals; Bupivacaine; Calibration; Chromatography, Liquid; Humans; Repro | 1999 |
[Clinical evaluation of accuracy of a new disposable pump (Syrinjector) for continuous epidural infusion].
Topics: Analgesia, Epidural; Anesthetics, Local; Bupivacaine; Disposable Equipment; Humans; Infusion Pumps; | 2000 |
Dual-opposite injection electrokinetic chromatography for the unbiased, simultaneous separation of cationic and anionic compounds.
Topics: Anions; Benzoates; Bupivacaine; Cations; Chromatography; Disopyramide; Electrophoresis, Capillary; H | 2000 |
On-Q system for managing trocar site pain after operative laparoscopy.
Topics: Anesthesia, Local; Bupivacaine; Female; Genital Diseases, Female; Humans; Infusion Pumps; Laparoscop | 2000 |
Determination of free concentrations of ropivacaine and bupivacaine in plasma from neonates using small-scale equilibrium-dialysis followed by liquid chromatography-mass spectrometry.
Topics: Amides; Anesthetics, Local; Bupivacaine; Calibration; Chromatography, Liquid; Dialysis; Humans; Infa | 2000 |
A way to facilitate dissection in laparoscopic cholecystectomy.
Topics: Anesthetics, Local; Bupivacaine; Cholecystectomy, Laparoscopic; Dissection; Humans; Injections, Intr | 2001 |
Gamma irradiation effects and EPR investigation on poly(lactide-co-glycolide) microspheres containing bupivacaine.
Topics: Alanine; Biphenyl Compounds; Bupivacaine; Cobalt Radioisotopes; Drug Stability; Electron Spin Resona | 2002 |