Carboxypeptidase B

A carboxypeptidase B that is encoded in the genome of human. [PRO:DNx, UniProtKB:P15086]

EC 3.4.17.2;
Pancreas-specific protein;
PASP

Research

Drug	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Publication(s)
guanidinoethylmercaptosuccinic acid	Homo sapiens (human)	Ki	1.1000	1	1
benzylsuccinic acid	Homo sapiens (human)	Ki	10.0000	1	1

This protein enables 4 target(s):

Target	Category	Definition
carboxypeptidase activity	molecular function	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain. [https://www.ebi.ac.uk/merops/about/glossary.shtml#CARBOXYPEPTIDASE]
protein binding	molecular function	Binding to a protein. [GOC:go_curators]
zinc ion binding	molecular function	Binding to a zinc ion (Zn). [GOC:ai]
metallocarboxypeptidase activity	molecular function	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. [https://www.ebi.ac.uk/merops/about/glossary.shtml#CARBOXYPEPTIDASE]

This protein is located in 1 target(s):

Target	Category	Definition
cytoplasmic vesicle	cellular component	A vesicle found in the cytoplasm of a cell. [GOC:ai, GOC:mah, GOC:vesicles]

This protein is active in 1 target(s):

Target	Category	Definition
extracellular space	cellular component	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]

This protein is involved in 1 target(s):

Target	Category	Definition
proteolysis	biological process	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. [GOC:bf, GOC:mah]