Compounds > 3-methylquinoxaline-2-carboxylic acid
Page last updated: 2024-12-11

3-methylquinoxaline-2-carboxylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-methylquinoxaline-2-carboxylic acid: cytotoxic and genotoxic [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6484678
SCHEMBL ID2056931
MeSH IDM0585094

Synonyms (26)

Synonym
BB 0252879
3-methyl-quinoxaline-2-carboxylic acid
AKOS000558927
3-methylquinoxaline-2-carboxylic acid
74003-63-7
FT-0672133
AG-0701
STL476641
SCHEMBL2056931
3-methyl-2-quinoxalinecarboxylic acid
DTXSID10424475
2-quinoxalinecarboxylic acid, 3-methyl-
mfcd03840415
J-512929
3-methyl-2-quinoxalinecarboxylic acid, vetranal(tm), analytical standard
BCP25035
3-methyl-quinoxaline-2-carboxylic acid 100 microg/ml in acetonitrile
mqca
CS-W016815
C76365
A917111
HY-W016099
3-methylquinoxaline-2-carboxylicacid
EN300-226768
PD088829
Z1198163353

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" The results indicate that 1,4-bisdesoxyquinocetone and MQCA are toxic to L-02 and Chang liver cells, and provide important new information towards understanding the olaquindox and quinocetone toxic mechanisms."( Cytotoxicity and genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic acid (MQCA) in human hepatocytes.
Ban, M; Fei, C; Wang, M; Wang, X; Xue, F; Zhang, K; Zhao, Z; Zheng, H, 2012)		0.62
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (83.33)24.3611
2020's2 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.94

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.94 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.94)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other12 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
aniline
[no description available]		7.1710anilines;
primary arylamine
quinoxalines
quinoxaline : A naphthyridine in which the nitrogens are at positions 1 and 4.		4120mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
malondialdehyde
Malondialdehyde: The dialdehyde of malonic acid.. malonaldehyde : A dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form.		2.110dialdehydebiomarker
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.		7.1710dihydrogen
olaquindox
olaquindox: used in prevention of swine dysentary; growth promoting additive in pig feed; structure		7.5720quinoxaline derivative
quinoxaline-2-carboxylic acid
[no description available]		3.2250
quinocetone
quinocetone: structure in first source		2.110
carbadox
Carbadox: An antibacterial agent that has been used in veterinary practice for treating swine dysentery and enteritis and for promoting growth. However, its use has been prohibited in the UK following reports of carcinogenicity and mutagenicity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p125)		2.1110quinoxaline derivative
ConditionIndicatedRelationship StrengthStudiesTrials
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.1310