Proteins > Myoglobin
Page last updated: 2024-08-07 21:05:55

Myoglobin

A myoglobin that is encoded in the genome of human. [PRO:DNx, UniProtKB:P02144]

Synonyms

Research

Bioassay Publications (1)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Compounds (1)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
acetaminophenHomo sapiens (human)IC502.300011

Enables

This protein enables 6 target(s):

TargetCategoryDefinition
peroxidase activitymolecular functionCatalysis of the reaction: a donor + a peroxide = an oxidized donor + 2 H2O. [GOC:curators]
oxygen carrier activitymolecular functionBinding to oxygen and delivering it to an acceptor molecule or a specific location. [GOC:ai]
heme bindingmolecular functionBinding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. [GOC:ai]
metal ion bindingmolecular functionBinding to a metal ion. [GOC:ai]
nitrite reductase activitymolecular functionCatalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor. [GOC:dos, GOC:jh]
oxygen bindingmolecular functionBinding to oxygen (O2). [GOC:jl]

Located In

This protein is located in 3 target(s):

TargetCategoryDefinition
cytosolcellular componentThe part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
sarcoplasmcellular componentThe cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. [ISBN:0198547684]
extracellular exosomecellular componentA vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. [GOC:BHF, GOC:mah, GOC:vesicles, PMID:15908444, PMID:17641064, PMID:19442504, PMID:19498381, PMID:22418571, PMID:24009894]

Involved In

This protein is involved in 6 target(s):

TargetCategoryDefinition
response to hypoxiabiological processAny process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. [GOC:hjd]
heart developmentbiological processThe process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. [GOC:jid, UBERON:0000948]
removal of superoxide radicalsbiological processAny process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2). [GOC:jl]
enucleate erythrocyte differentiationbiological processThe process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus. [GOC:go_curators]
brown fat cell differentiationbiological processThe process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. [PMID:12588810]
oxygen transportbiological processThe directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]