N-desmethylatomoxetine: an atomoxetine metabolite; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
ID Source | ID |
---|---|
PubMed CID | 11715688 |
SCHEMBL ID | 4624371 |
MeSH ID | M0424472 |
Synonym |
---|
n-desmethylatomoxetine |
435293-68-8 |
benzenepropanamine, .gamma.-(2-methylphenoxy)-, (.gamma.r)- |
n-desmethylatomoxetine, (-)- |
0OAZ8PB6S3 , |
SCHEMBL4624371 |
benzenepropanamine, gamma-(2-methylphenoxy)-, (gammar)- |
unii-0oaz8pb6s3 |
Q27237031 |
(3r)-3-(2-methylphenoxy)-3-phenylpropan-1-amine |
Excerpt | Reference | Relevance |
---|---|---|
" The validated method was successfully applied to a pharmacokinetic study in humans." | ( Determination of atomoxetine metabolites in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study. Bae, JW; Choi, CI; Jang, CG; Lee, HI; Lee, SY; Sohn, UD, 2012) | 0.38 |
" The Cmax and t1/2 for 4-HAT were lower and longer in the CYP2D6*10/*10 group than those in the CYP2D6*wt/*wt group, but the AUC0-∞ was not different between these groups." | ( Effects of the CYP2D6*10 allele on the pharmacokinetics of atomoxetine and its metabolites. Bae, JW; Byeon, JY; Chung, MW; Jang, CG; Jang, JH; Kim, IS; Kim, SH; Kim, YH; Lee, SY; Lee, YJ; Na, HS, 2015) | 0.42 |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (33.33) | 29.6817 |
2010's | 4 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.54) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 2 (33.33%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 4 (66.67%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |