Page last updated: 2024-11-12

n-desmethylatomoxetine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

N-desmethylatomoxetine: an atomoxetine metabolite; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11715688
SCHEMBL ID4624371
MeSH IDM0424472

Synonyms (10)

Synonym
n-desmethylatomoxetine
435293-68-8
benzenepropanamine, .gamma.-(2-methylphenoxy)-, (.gamma.r)-
n-desmethylatomoxetine, (-)-
0OAZ8PB6S3 ,
SCHEMBL4624371
benzenepropanamine, gamma-(2-methylphenoxy)-, (gammar)-
unii-0oaz8pb6s3
Q27237031
(3r)-3-(2-methylphenoxy)-3-phenylpropan-1-amine

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" The validated method was successfully applied to a pharmacokinetic study in humans."( Determination of atomoxetine metabolites in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study.
Bae, JW; Choi, CI; Jang, CG; Lee, HI; Lee, SY; Sohn, UD, 2012
)
0.38
" The Cmax and t1/2 for 4-HAT were lower and longer in the CYP2D6*10/*10 group than those in the CYP2D6*wt/*wt group, but the AUC0-∞ was not different between these groups."( Effects of the CYP2D6*10 allele on the pharmacokinetics of atomoxetine and its metabolites.
Bae, JW; Byeon, JY; Chung, MW; Jang, CG; Jang, JH; Kim, IS; Kim, SH; Kim, YH; Lee, SY; Lee, YJ; Na, HS, 2015
)
0.42
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.54

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.54 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.54)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (33.33%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (66.67%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]