Proteins > transactivating tegument protein VP16 [Human herpesvirus 1]
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transactivating tegument protein VP16 [Human herpesvirus 1]

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (78)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
doxorubicin hydrochlorideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.888020
cycloheximideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.421010
cytarabineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5016.247010
2,4-diacetylphloroglucinolHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC504.561010
nitroxolineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC506.357010
helenalinHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC504.374010
metoprineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5011.949010
etoposideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.872020
triazinateHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.849010
simvastatinHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC504.426010
chlormidazoleHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.404010
9-aminocamptothecinHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC501.991010
3-hydroxy naphthoic acid hydrazideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5022.816020
1,10-phenanthroline-5,6-dioneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5013.136010
streptovitacin aHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.328010
pyridabenHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.401020
diphyllinHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC502.300010
carboxyamido-triazoleHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.403010
methotrexateHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.879020
nsc-141549Human alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.878010
chrysomycin bHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC507.597010
demecolcineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.895010
brusatolHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC509.487010
3-(4-aminophenyl)-2h-chromen-2-oneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.857520
nsc606985Human alphaherpesvirus 1 (Herpes simplex virus type 1)IC501.310010
nsc 680410Human alphaherpesvirus 1 (Herpes simplex virus type 1)IC5011.559010
nsc697923Human alphaherpesvirus 1 (Herpes simplex virus type 1)IC506.323010
n,n-dimethyldaunorubicinHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC503.206010
N-benzylquinazolin-4-amineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.430010
2-[[5-(1-benzotriazolylmethyl)-1,3,4-oxadiazol-2-yl]thio]-N-[(4-fluorophenyl)methyl]-N-phenylacetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.355010
3-(2-chlorophenyl)-1-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-1-[2-(1-pyrrolidinyl)ethyl]ureaHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5023.777520
2-acetamido-3-(4-methoxyphenyl)-N-[1-(1-phenyl-5-tetrazolyl)-4-piperidinyl]propanamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.871020
3-chloro-4-[4-(4-fluorophenyl)sulfonyl-1-piperazinyl]-N,N-dimethylbenzenesulfonamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC509.395010
N-[4-(2-methyl-1-methylsulfonyl-2,3-dihydroindol-5-yl)-2-thiazolyl]-2-thiophen-2-ylacetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5024.162320
4-(cyclohexylamino)-2-(3,5-dimethyl-1-pyrazolyl)-5-pyrimidinecarboxylic acid ethyl esterHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5045.355010
N1-(6-bromo-4-quinazolinyl)-N4,N4-dimethylbenzene-1,4-diamineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC503.197010
9-(dimethylamino)-3-(4-methoxyphenyl)-4-pyrido[1,2]thieno[3,4-d]pyrimidinoneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5014.247020
4-(2,4-dichlorophenyl)-2-[(1-oxo-2-phenylethyl)amino]-3-thiophenecarboxamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.404010
2-imino-10-methyl-N-[2-(4-morpholinyl)ethyl]-5-oxo-1-(3-pyridinylmethyl)-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5013.490010
SMER 28Human alphaherpesvirus 1 (Herpes simplex virus type 1)IC505.958010
N-[(4-methoxyphenyl)methyl]-2-methyl-4,9-dioxo-3-benzo[f]benzofurancarboxamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC501.182010
1-(5-isoquinolinyl)-3-(2-phenylethyl)thioureaHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.413010
2-chloro-N-[4-(N-propan-2-ylanilino)phenyl]acetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5014.566010
2-chloro-1-[4-[(3-methylphenyl)methyl]-1-piperazinyl]ethanoneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5011.952010
N-[4-(4-methylphenyl)-2-thiazolyl]-1-thiophen-2-ylsulfonyl-4-piperidinecarboxamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.404010
N-(1H-benzimidazol-2-yl)-4-(3-methylphenoxy)butanamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5039.841020
6-thioguanosineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC503.368010
6-(2-methyl-3-imidazo[1,2-a]pyridinyl)-1H-pyrimidine-2-thioneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.822010
5-amino-1-formylisoquinoline thiosemicarbazoneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC502.657020
N-(1,3-benzothiazol-2-yl)-2-methoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC507.904010
N-[4-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-5-methyl-2-thiazolyl]-2-(4-morpholinyl)acetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.413010
6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dioneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5039.841020
5-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-4-triazolecarboxamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5023.096010
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(3-methyl-4-oxo-1-phthalazinyl)acetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.382010
4-[[2-[4-(4-chlorophenyl)-1-piperazinyl]-1-oxoethyl]amino]benzoic acid methyl esterHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.864320
4-(3,4-dihydro-2H-quinolin-1-ylsulfonyl)-N-(5-ethyl-1,3,4-oxadiazol-2-yl)benzamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC506.800010
2-(1H-benzimidazol-2-ylthio)-1-[2,5-dimethyl-1-(2-oxolanylmethyl)-3-pyrrolyl]ethanoneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC507.318010
1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)-2-[(6-methyl-2-nitro-3-pyridinyl)oxy]ethanoneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC507.560520
2-(3-chloro-N-(2-chloro-1-oxoethyl)anilino)-N-cyclohexyl-2-(3-pyridinyl)acetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC505.370020
2-chloro-N-(1,2-diphenylethyl)acetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5017.911020
N-(3-acetylphenyl)-2-[[6-chloro-3-(2-hydroxypropyl)-4-methyl-2-oxo-1-benzopyran-7-yl]oxy]acetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.872010
N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-5,6-dimethyl-4-thieno[2,3-d]pyrimidinamineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.397020
su 9516Human alphaherpesvirus 1 (Herpes simplex virus type 1)IC5012.744010
2-(4-(dimethylamino)styryl)benzothiazoleHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5019.800010
cycloheximideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.413010
2-(4-chloro-N-(2-chloro-1-oxoethyl)anilino)-N-cyclohexyl-2-(4-methoxyphenyl)acetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC505.268010
5-amino-N-(2-methoxy-5-methylphenyl)-1-[[3-(trifluoromethyl)phenyl]methyl]-4-triazolecarboxamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5039.833010
6-(3,5-dimethyl-4-isoxazolyl)-N-[(3-methoxyphenyl)methyl]-4-quinazolinamineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.865020
4-[2-[(6-chloro-4-quinazolinyl)amino]ethyl]phenolHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.398010
sri 62320Human alphaherpesvirus 1 (Herpes simplex virus type 1)IC501.219010
fractalsHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC502.240010
4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC502.080010
N-[1-(2,3-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.403010
N-[1-(3,4-dimethylphenyl)-4,5,6,7-tetrahydroindazol-4-yl]-2,5-dimethyl-3-pyrazolecarboxamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5085.403010
N-[(5-chloro-8-hydroxy-7-quinolinyl)-cyclopropylmethyl]acetamideHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC509.302010
1-[3-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanoneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC506.886010
3-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-6-(phenylmethyl)-2H-1,2,4-triazin-5-oneHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5035.872520
8-azainosineHuman alphaherpesvirus 1 (Herpes simplex virus type 1)IC5010.115010