| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
chlorine
chloride : A halide anion formed when chlorine picks up an electron to form an an anion. | 2.03 | 1 | 0 | halide anion;
monoatomic chlorine | cofactor;
Escherichia coli metabolite;
human metabolite |
diethyl phosphate
diethyl phosphate: RN given refers to parent cpd. diethyl hydrogen phosphate : A dialkyl phosphate having ethyl as the alkyl group. | 2.48 | 2 | 0 | dialkyl phosphate | human xenobiotic metabolite;
mouse metabolite |
o,o-diethyl phosphorothionate
O,O-diethyl phosphorothionate: metabolite of organothiophosphorous insecticides; structure given in first source. O,O-diethyl hydrogen thiophosphate : An organic thiophosphate that is the diethyl ester of phosphorothioic O,O,O-acid. | 2.82 | 3 | 0 | organic thiophosphate | human xenobiotic metabolite;
mouse metabolite |
dimethoate
Dimethoate: An organothiophosphorus cholinesterase inhibitor that is used as a systemic and contact insecticide.. dimethoate : A monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group. | 2.7 | 3 | 0 | monocarboxylic acid amide;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic |
malathion
Malathion: A wide spectrum aliphatic organophosphate insecticide widely used for both domestic and commercial agricultural purposes.. malathion : A racemate comprising equimolar amounts of (R) and (S)-malathion. It is a broad spectrum organophosphate proinsecticide used to control a wide range of pests including Coleoptera, Diptera, fruit flies, mosquitos and spider mites.. diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate : A diester that is diethyl succinate in which position 2 is substituted by a (dimethoxyphosphorothioyl)thio group. | 2.43 | 2 | 0 | diester;
ethyl ester;
organic thiophosphate | |
naled
Naled: An organophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.. naled : An dialkyl phosphate resulting from the formal condensation of the acidic hydroxy group of dimethyl hydrogen phosphate with the alcoholic hydroxy group of 1,2-dibromo-2,2-dichloroethanol. An organophosphate insecticide, it is no longer approved for use within the European Union. | 1.96 | 1 | 0 | dialkyl phosphate;
organobromine compound;
organochlorine compound;
organophosphate insecticide | acaricide;
agrochemical;
antibacterial agent;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor |
trichlorfon
Trichlorfon: An organochlorophosphate cholinesterase inhibitor that is used as an insecticide for the control of flies and roaches. It is also used in anthelmintic compositions for animals. (From Merck, 11th ed). trichlorfon : A phosphonic ester that is dimethyl phosphonate in which the hydrogen atom attched to the phosphorous is substituted by a 2,2,2-trichloro-1-hydroxyethyl group. | 1.96 | 1 | 0 | organic phosphonate;
organochlorine compound;
phosphonic ester | agrochemical;
anthelminthic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
insecticide |
o,o-diethyl dithiophosphate
O,O-diethyl dithiophosphate: structure given in first source | 2.4 | 2 | 0 | organic thiophosphate | |
phosmet
Phosmet: An organothiophosphorus insecticide that has been used to control pig mange. | 1.96 | 1 | 0 | organic thiophosphate;
organothiophosphate insecticide;
phthalimides | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
dimethyl phosphate
dimethyl phosphate: excreted in urine after exposure to mevinphos; RN given refers to parent cpd; structure | 2.41 | 2 | 0 | dialkyl phosphate | |
bromophos
bromophos: minor descriptor (72-83); on-line & Index Medicus search ORGANOTHIOPHOSPHORUS COMPOOUNDS (72) & INSECTICIDES (72) & INSECTICIDES, ORGANOTHIOPHOSPHATE (73-83); structure | 1.96 | 1 | 0 | organic thiophosphate | |
terbufos
[no description available] | 2.6 | 1 | 0 | organic thiophosphate;
organosulfur compound;
organothiophosphate insecticide | agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
nematicide |
thiophosphoric acid
thiophosphoric acid: RN given refers to parent cpd | 2.17 | 1 | 0 | phosphorothioic acid | |
o,o-dimethyl phosphorothionate
O,O-dimethyl phosphorothionate: metabolite of phosmet; RN given refers to parent cpd | 3.5 | 8 | 0 | organic thiophosphate | |
maleamic acid
maleamic acid: structure. maleamic acid : A dicarboxylic acid monoamide of maleamic acid. | 1.98 | 1 | 0 | alpha,beta-unsaturated monocarboxylic acid;
dicarboxylic acid monoamide | bacterial xenobiotic metabolite;
Escherichia coli metabolite |