A prolyl endopeptidase FAP that is encoded in the genome of mouse. [OMA:P97321, PRO:DNx]
EC 3.4.21.26;
Dipeptidyl peptidase FAP;
3.4.14.5;
Fibroblast activation protein alpha;
FAPalpha;
Gelatine degradation protease FAP;
3.4.21.-;
Integral membrane serine protease;
Post-proline cleaving enzyme;
Serine inte
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| n-(n-(phenyl)butyryl-l-prolyl)pyrrolidine | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| sitagliptin | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| vildagliptin | Mus musculus (house mouse) | IC50 | 52.0000 | 1 | 1 |
| talabostat | Mus musculus (house mouse) | IC50 | 0.0673 | 3 | 3 |
| linagliptin | Mus musculus (house mouse) | IC50 | 0.3700 | 2 | 2 |
| kyp 2047 | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |