Page last updated: 2024-08-07 23:00:20
Fatty-acid amide hydrolase 1
A fatty-acid amide hydrolase 1 that is encoded in the genome of mouse. [OMA:O08914, PRO:DNx]
Synonyms
EC 3.5.1.99;
Anandamide amidohydrolase 1;
Fatty acid ester hydrolase;
3.1.1.-;
Oleamide hydrolase 1
Research
Bioassay Publications (9)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (15)
Drugs with Inhibition Measurements
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| anandamide | Mus musculus (house mouse) | Km | 15.0000 | 1 | 1 |
α-Ketoheterocycle inhibitors of fatty acid amide hydrolase: exploration of conformational constraints in the acyl side chain.Bioorganic & medicinal chemistry, , May-01, Volume: 22, Issue:9, 2014
Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase.Bioorganic & medicinal chemistry letters, , Nov-15, Volume: 18, Issue:22, 2008
Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity.Bioorganic & medicinal chemistry letters, , Mar-01, Volume: 15, Issue:5, 2005