Page last updated: 2024-08-07 23:00:20
Fatty-acid amide hydrolase 1
A fatty-acid amide hydrolase 1 that is encoded in the genome of mouse. [OMA:O08914, PRO:DNx]
Synonyms
EC 3.5.1.99;
Anandamide amidohydrolase 1;
Fatty acid ester hydrolase;
3.1.1.-;
Oleamide hydrolase 1
Research
Bioassay Publications (9)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (15)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| paraoxon | Mus musculus (house mouse) | IC50 | 5.9000 | 1 | 1 |
| o,o-diethyl o-3,5,6-trichloro-2-pyridyl phosphate | Mus musculus (house mouse) | IC50 | 0.4600 | 1 | 1 |
| methotrexate | Mus musculus (house mouse) | IC50 | 0.0800 | 1 | 1 |
| 2-[2-[4-(2-fluorophenyl)-1-piperazinyl]-2-oxoethyl]-1,1-dioxo-1,2-benzothiazol-3-one | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 0 |
| 3-(1-piperidinylsulfonyl)-N-(2-thiazolyl)benzamide | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 0 |
| 2-furanyl-[4-(4-phenoxyphenyl)sulfonyl-1-piperazinyl]methanone | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 0 |
| urb 597 | Mus musculus (house mouse) | IC50 | 0.0046 | 1 | 1 |
| N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 0 |
| 4-(1-methyl-3-indolyl)-N-propan-2-ylbutanamide | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 0 |
| 4-[2-(1-cyclohexenyl)ethyl]-1-cyclohexyl-3-pyridin-4-ylpiperazine-2,5-dione | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 0 |
| N-(3-acetylphenyl)-3,5-dimethyl-4-isoxazolesulfonamide | Mus musculus (house mouse) | IC50 | 50.0000 | 1 | 0 |
| ol-135 | Mus musculus (house mouse) | Ki | 0.0047 | 3 | 3 |
| ly2183240 | Mus musculus (house mouse) | IC50 | 0.0130 | 1 | 1 |
| pf 04457845 | Mus musculus (house mouse) | IC50 | 0.0074 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| anandamide | Mus musculus (house mouse) | Km | 15.0000 | 1 | 1 |