Page last updated: 2024-08-07 15:12:13
Neuraminidase
[no definition available]
Synonyms
Research
Bioassay Publications (50)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (24.00) | 29.6817 |
| 2010's | 36 (72.00) | 24.3611 |
| 2020's | 2 (4.00) | 2.80 |
Compounds (56)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| 2-hydroxyphenethylamine | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 870.0000 | 1 | 1 |
| catechin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 100.0000 | 3 | 3 |
| ethopabate | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 0.2200 | 1 | 1 |
| 1-hydroxy-2-naphthoic acid | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 1,000.0000 | 1 | 1 |
| hesperidin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 100.0000 | 3 | 3 |
| zanamivir | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 41.7026 | 122 | 122 |
| zanamivir | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 0.0002 | 4 | 4 |
| oseltamivir | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 13.0076 | 82 | 83 |
| oseltamivir | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 0.0005 | 2 | 2 |
| 2-deoxy-2,3-dehydro-n-acetylneuraminic acid | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 1,075,064.3765 | 8 | 8 |
| 2-deoxy-2,3-dehydro-n-acetylneuraminic acid | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 4.9500 | 2 | 2 |
| honokiol | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 15.7450 | 2 | 2 |
| prunin protein, prunus | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 3.7650 | 2 | 2 |
| liquiritigenin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 5.2000 | 2 | 2 |
| bcx 1812 | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 0.9460 | 11 | 11 |
| (2S)-5,7-dihydroxy-6,8-dimethylflavanone | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 326.3550 | 2 | 2 |
| (+)-epicatechin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 100.0000 | 3 | 3 |
| scutellarin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 52.6000 | 3 | 3 |
| naringenin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 100.0000 | 3 | 3 |
| 1-[4-carboxy-2-(3-pentylamino)phenyl]-5,5-bis(hydroxymethyl)pyrrolidin-2-one | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 24.0217 | 2 | 2 |
| 4-amino-2-deoxy-2,3-didehydro-n-acetylneuraminic acid | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 159,981.6600 | 2 | 2 |
| 4-amino-2-deoxy-2,3-didehydro-n-acetylneuraminic acid | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 0.0400 | 1 | 1 |
| bana 113 | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 1,249,890.0000 | 2 | 2 |
| gs 4071 | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 22.1275 | 50 | 50 |
| laninamivir | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 0.0115 | 43 | 43 |
| likviriton | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 104.6200 | 5 | 5 |
| N-[[(4,6-dimethyl-2-pyrimidinyl)amino]-sulfanylidenemethyl]benzamide | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 2.0946 | 1 | 2 |
| dryocrassin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 3.6000 | 1 | 1 |
| quercetin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 53.9250 | 4 | 4 |
| quercetin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 3.8000 | 1 | 1 |
| formononetin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 44.9271 | 7 | 7 |
| vitexin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 47.0667 | 3 | 3 |
| apigenin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 34.9000 | 4 | 4 |
| apigenin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 37.1000 | 1 | 1 |
| luteolin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 32.6500 | 4 | 4 |
| luteolin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 19.6000 | 1 | 1 |
| herbacetin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 8.9000 | 1 | 1 |
| herbacetin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 13.7000 | 1 | 1 |
| luteolin-7-glucoside | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 52.7333 | 3 | 3 |
| gossypetin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 2.6000 | 1 | 1 |
| gossypetin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 7.7000 | 1 | 1 |
| apigetrin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 46.9000 | 1 | 1 |
| apigetrin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 53.8000 | 1 | 1 |
| rutin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 68.5750 | 4 | 4 |
| rutin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 33.8000 | 1 | 1 |
| kaempferol | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 38.5750 | 4 | 4 |
| kaempferol | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 21.1000 | 1 | 1 |
| genistein | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 98.2667 | 3 | 3 |
| sulfuretin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 39.0000 | 3 | 3 |
| chrysin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 43.9867 | 3 | 3 |
| hispidulin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 35.1667 | 3 | 3 |
| myricetin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 68.0667 | 3 | 3 |
| daidzein | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 36.8333 | 3 | 3 |
| astragalin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 38.4000 | 1 | 1 |
| astragalin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 33.0000 | 1 | 1 |
| eurycarpin b | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 4.5950 | 4 | 4 |
| kaempferol-3-o-rutinoside | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 31.7000 | 1 | 1 |
| kaempferol-3-o-rutinoside | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 32.7000 | 1 | 1 |
| 3-deoxysappanchalcone | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 24.3000 | 1 | 1 |
| kaempferol-7-methyl ether | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 65.8000 | 3 | 3 |
| sophoricoside | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 100.0000 | 3 | 3 |
| tetrahydroxycurcumin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 63.8000 | 1 | 1 |
| a 315675 | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 0.0002 | 1 | 1 |
| cs 8958 | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 0.4281 | 35 | 35 |
| tamiphosphor | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 0.0018 | 1 | 1 |
| 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 23.6200 | 4 | 4 |
| 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 41.3700 | 1 | 1 |
| Licoflavone B | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 8.9000 | 3 | 3 |
| glabrol | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 5.1675 | 4 | 4 |
| hispidin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 37.6667 | 3 | 3 |
| davallialactone | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 19.0333 | 3 | 3 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| astragalin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | EC50 | 72.8000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| hispidin | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Kiuc | 43.0000 | 1 | 1 |
| davallialactone | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Kiuc | 27.6000 | 1 | 1 |
Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity.European journal of medicinal chemistry, , Feb-01, Volume: 187, 2020
Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses.European journal of medicinal chemistry, , Jun-25, Volume: 154, 2018
Structural and Functional Analysis of Anti-Influenza Activity of 4-, 7-, 8- and 9-Deoxygenated 2,3-Difluoro- N-acetylneuraminic Acid Derivatives.Journal of medicinal chemistry, , 03-08, Volume: 61, Issue:5, 2018
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.Journal of medicinal chemistry, , Jul-26, Volume: 61, Issue:14, 2018
Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors.Journal of medicinal chemistry, , 06-09, Volume: 59, Issue:11, 2016
A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions.Journal of medicinal chemistry, , 05-26, Volume: 59, Issue:10, 2016
Anti-influenza activities of polyphenols from the medicinal mushroom Phellinus baumii.Bioorganic & medicinal chemistry letters, , Aug-15, Volume: 25, Issue:16, 2015
Development of novel potent orally bioavailable oseltamivir derivatives active against resistant influenza A.Journal of medicinal chemistry, , Feb-13, Volume: 57, Issue:3, 2014
Bifunctional thiosialosides inhibit influenza virus.Bioorganic & medicinal chemistry letters, , Jan-15, Volume: 24, Issue:2, 2014
Structure-based design and synthesis of C-1- and C-4-modified analogs of zanamivir as neuraminidase inhibitors.Journal of medicinal chemistry, , Feb-14, Volume: 56, Issue:3, 2013
Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities.European journal of medicinal chemistry, , Volume: 54, 2012
Development of oseltamivir phosphonate congeners as anti-influenza agents.Journal of medicinal chemistry, , Oct-25, Volume: 55, Issue:20, 2012
The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase.Bioorganic & medicinal chemistry letters, , Dec-01, Volume: 21, Issue:23, 2011
Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir.Bioorganic & medicinal chemistry, , Aug-15, Volume: 19, Issue:16, 2011
Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses.Bioorganic & medicinal chemistry, , Jun-01, Volume: 18, Issue:11, 2010
Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles.Journal of medicinal chemistry, , Oct-28, Volume: 53, Issue:20, 2010
Synergistic effect of zanamivir-porphyrin conjugates on inhibition of neuraminidase and inactivation of influenza virus.Journal of medicinal chemistry, , Aug-13, Volume: 52, Issue:15, 2009
Susceptibility of highly pathogenic H5N1 influenza viruses to the neuraminidase inhibitor oseltamivir differs in vitro and in a mouse model.Antimicrobial agents and chemotherapy, , Volume: 53, Issue:7, 2009
CS-8958, a prodrug of the new neuraminidase inhibitor R-125489, shows long-acting anti-influenza virus activity.Antimicrobial agents and chemotherapy, , Volume: 53, Issue:1, 2009
Limited inhibitory effects of oseltamivir and zanamivir on human sialidases.Antimicrobial agents and chemotherapy, , Volume: 52, Issue:10, 2008
Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase.Journal of medicinal chemistry, , Jul-10, Volume: 51, Issue:13, 2008
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.European journal of medicinal chemistry, , Volume: 43, Issue:3, 2008
Synthesis of potent pyrrolidine influenza neuraminidase inhibitors.Bioorganic & medicinal chemistry letters, , Mar-01, Volume: 18, Issue:5, 2008
Total synthesis of dryocrassin ABBA and its analogues with potential inhibitory activity against drug-resistant neuraminidases.Bioorganic & medicinal chemistry, , 09-01, Volume: 27, Issue:17, 2019
Synthesis and biological evaluation of NHEuropean journal of medicinal chemistry, , Dec-01, Volume: 141, 2017
1,2,3-Triazolyl-4-oxoquinolines: A feasible beginning for promising chemical structures to inhibit oseltamivir-resistant influenza A and B viruses.Bioorganic & medicinal chemistry, , Dec-15, Volume: 23, Issue:24, 2015
Design and synthesis of 6-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylate derivatives as neuraminidase inhibitors.European journal of medicinal chemistry, , Aug-18, Volume: 83, 2014
Computer-guided approach to access the anti-influenza activity of licorice constituents.Journal of natural products, , Mar-28, Volume: 77, Issue:3, 2014
Bifunctional thiosialosides inhibit influenza virus.Bioorganic & medicinal chemistry letters, , Jan-15, Volume: 24, Issue:2, 2014
Further discovery of caffeic acid derivatives as novel influenza neuraminidase inhibitors.Bioorganic & medicinal chemistry, , Dec-15, Volume: 21, Issue:24, 2013
Caffeic acid derivatives: a new type of influenza neuraminidase inhibitors.Bioorganic & medicinal chemistry letters, , Jun-15, Volume: 23, Issue:12, 2013
Synthesis and in vitro study of novel neuraminidase inhibitors against avian influenza virus.Bioorganic & medicinal chemistry, , Mar-15, Volume: 20, Issue:6, 2012
The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase.Bioorganic & medicinal chemistry letters, , Dec-01, Volume: 21, Issue:23, 2011
Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors.Bioorganic & medicinal chemistry, , Apr-01, Volume: 19, Issue:7, 2011
C-Methylated Flavonoids from Cleistocalyx operculatus and Their Inhibitory Effects on Novel Influenza A (H1N1) Neuraminidase.Journal of natural products, , Oct-22, Volume: 73, Issue:10, 2010
Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai.Journal of medicinal chemistry, , Jan-28, Volume: 53, Issue:2, 2010
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.Bioorganic & medicinal chemistry, , Oct-01, Volume: 17, Issue:19, 2009
Susceptibility of highly pathogenic H5N1 influenza viruses to the neuraminidase inhibitor oseltamivir differs in vitro and in a mouse model.Antimicrobial agents and chemotherapy, , Volume: 53, Issue:7, 2009
CS-8958, a prodrug of the new neuraminidase inhibitor R-125489, shows long-acting anti-influenza virus activity.Antimicrobial agents and chemotherapy, , Volume: 53, Issue:1, 2009
Limited inhibitory effects of oseltamivir and zanamivir on human sialidases.Antimicrobial agents and chemotherapy, , Volume: 52, Issue:10, 2008
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.European journal of medicinal chemistry, , Volume: 43, Issue:3, 2008
Synthesis of potent pyrrolidine influenza neuraminidase inhibitors.Bioorganic & medicinal chemistry letters, , Mar-01, Volume: 18, Issue:5, 2008
Design, synthesis, inhibitory activity, and SAR studies of pyrrolidine derivatives as neuraminidase inhibitors.Bioorganic & medicinal chemistry, , Apr-01, Volume: 15, Issue:7, 2007
A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1-N9 Neuraminidases: Insight into Neuraminidase-Inhibitor Interactions.Journal of medicinal chemistry, , 05-26, Volume: 59, Issue:10, 2016
Structure-based design and synthesis of C-1- and C-4-modified analogs of zanamivir as neuraminidase inhibitors.Journal of medicinal chemistry, , Feb-14, Volume: 56, Issue:3, 2013
Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: the hydrophobic side chain influences type A subtype selectivity.Bioorganic & medicinal chemistry, , Jul-15, Volume: 20, Issue:14, 2012
Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses.Bioorganic & medicinal chemistry, , Jun-01, Volume: 18, Issue:11, 2010
Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles.Journal of medicinal chemistry, , Oct-28, Volume: 53, Issue:20, 2010
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.European journal of medicinal chemistry, , Volume: 43, Issue:3, 2008
Peramivir conjugates as orally available agents against influenza H275Y mutant.European journal of medicinal chemistry, , Feb-10, Volume: 145, 2018
Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors.Journal of medicinal chemistry, , 06-09, Volume: 59, Issue:11, 2016
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.European journal of medicinal chemistry, , Volume: 43, Issue:3, 2008
The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase.Bioorganic & medicinal chemistry letters, , Dec-01, Volume: 21, Issue:23, 2011
Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses.Bioorganic & medicinal chemistry, , Jun-01, Volume: 18, Issue:11, 2010
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.European journal of medicinal chemistry, , Volume: 43, Issue:3, 2008
Design, synthesis, inhibitory activity, and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitors.Bioorganic & medicinal chemistry, , Apr-01, Volume: 16, Issue:7, 2008
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.European journal of medicinal chemistry, , Volume: 43, Issue:3, 2008
Discovery of hydrazide-containing oseltamivir analogues as potent inhibitors of influenza A neuraminidase.European journal of medicinal chemistry, , Oct-05, Volume: 221, 2021
Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity.European journal of medicinal chemistry, , Feb-01, Volume: 187, 2020
[no title available]European journal of medicinal chemistry, , Sep-15, Volume: 178, 2019
Discovery of novel acylhydrazone neuraminidase inhibitors.European journal of medicinal chemistry, , Jul-01, Volume: 173, 2019
Discovery of C-1 modified oseltamivir derivatives as potent influenza neuraminidase inhibitors.European journal of medicinal chemistry, , Feb-25, Volume: 146, 2018
Design, synthesis, and evaluation of carboxyl-modified oseltamivir derivatives with improved lipophilicity as neuraminidase inhibitors.Bioorganic & medicinal chemistry letters, , 11-15, Volume: 28, Issue:21, 2018
Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses.European journal of medicinal chemistry, , Jun-25, Volume: 154, 2018
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.Journal of medicinal chemistry, , Jul-26, Volume: 61, Issue:14, 2018
Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors.Journal of medicinal chemistry, , 06-09, Volume: 59, Issue:11, 2016
Discovery of N-substituted oseltamivir derivatives as potent and selective inhibitors of H5N1 influenza neuraminidase.Journal of medicinal chemistry, , Oct-23, Volume: 57, Issue:20, 2014
Development of novel potent orally bioavailable oseltamivir derivatives active against resistant influenza A.Journal of medicinal chemistry, , Feb-13, Volume: 57, Issue:3, 2014
Oseltamivir analogues bearing N-substituted guanidines as potent neuraminidase inhibitors.Journal of medicinal chemistry, , Apr-10, Volume: 57, Issue:7, 2014
Synthesis and in vitro study of novel neuraminidase inhibitors against avian influenza virus.Bioorganic & medicinal chemistry, , Mar-15, Volume: 20, Issue:6, 2012
Development of oseltamivir phosphonate congeners as anti-influenza agents.Journal of medicinal chemistry, , Oct-25, Volume: 55, Issue:20, 2012
Design, synthesis, inhibitory activity, and SAR studies of hydrophobic p-aminosalicylic acid derivatives as neuraminidase inhibitors.Bioorganic & medicinal chemistry, , Apr-01, Volume: 16, Issue:7, 2008
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.Bioorganic & medicinal chemistry, , Aug-01, Volume: 16, Issue:15, 2008
QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network.European journal of medicinal chemistry, , Volume: 43, Issue:3, 2008
Computer-guided approach to access the anti-influenza activity of licorice constituents.Journal of natural products, , Mar-28, Volume: 77, Issue:3, 2014
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.Bioorganic & medicinal chemistry, , Aug-01, Volume: 16, Issue:15, 2008
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.Bioorganic & medicinal chemistry, , Oct-01, Volume: 17, Issue:19, 2009
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.Bioorganic & medicinal chemistry, , Aug-01, Volume: 16, Issue:15, 2008
Computer-guided approach to access the anti-influenza activity of licorice constituents.Journal of natural products, , Mar-28, Volume: 77, Issue:3, 2014
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.Bioorganic & medicinal chemistry, , Aug-01, Volume: 16, Issue:15, 2008
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.Bioorganic & medicinal chemistry, , Oct-01, Volume: 17, Issue:19, 2009
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.Bioorganic & medicinal chemistry, , Aug-01, Volume: 16, Issue:15, 2008
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.Bioorganic & medicinal chemistry, , Oct-01, Volume: 17, Issue:19, 2009
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.Bioorganic & medicinal chemistry, , Aug-01, Volume: 16, Issue:15, 2008
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.Bioorganic & medicinal chemistry, , Oct-01, Volume: 17, Issue:19, 2009
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.Bioorganic & medicinal chemistry, , Aug-01, Volume: 16, Issue:15, 2008
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.Bioorganic & medicinal chemistry, , Oct-01, Volume: 17, Issue:19, 2009
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities.Bioorganic & medicinal chemistry, , Aug-01, Volume: 16, Issue:15, 2008
Flavonoids from Matteuccia struthiopteris and Their Anti-influenza Virus (H1N1) Activity.Journal of natural products, , May-22, Volume: 78, Issue:5, 2015
Neuraminidase inhibitory activities of flavonols isolated from Rhodiola rosea roots and their in vitro anti-influenza viral activities.Bioorganic & medicinal chemistry, , Oct-01, Volume: 17, Issue:19, 2009