pyrazinoic acid has been researched along with Sensitivity and Specificity in 4 studies
pyrazinoic acid: active metabolite of pyrazinamide; structure
pyrazine-2-carboxylic acid : The parent compound of the class of pyrazinecarboxylic acids, that is pyrazine bearing a single carboxy substituent. The active metabolite of the antitubercular drug pyrazinamide.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyrazinamide (PZA) is an important component of first-line drugs because of its distinctive capability to kill subpopulations of persistent Mycobacterium tuberculosis (MTB)." | 7.91 | Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan. ( Afzal, MT; Ali, S; Khan, AS; Khan, MT; Malik, SI; Masood, N; Nadeem, T, 2019) |
| "A new, precise, and very selective method for increasing the impact and assessment of 3-nitrotyrosine (3-Nty) as a biomarker for early diagnosis of liver cirrhosis with minimal hepatic encephalopathy (MHE) disease was developed." | 7.83 | Nano optical sensor binuclear Pt-2-pyrazinecarboxylic acid -bipyridine for enhancement of the efficiency of 3-nitrotyrosine biomarker for early diagnosis of liver cirrhosis with minimal hepatic encephalopathy. ( Al-Radadi, NS; Attia, MS, 2016) |
| "Pyrazinamide (PZA) is an important component of first-line drugs because of its distinctive capability to kill subpopulations of persistent Mycobacterium tuberculosis (MTB)." | 3.91 | Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan. ( Afzal, MT; Ali, S; Khan, AS; Khan, MT; Malik, SI; Masood, N; Nadeem, T, 2019) |
| "A new, precise, and very selective method for increasing the impact and assessment of 3-nitrotyrosine (3-Nty) as a biomarker for early diagnosis of liver cirrhosis with minimal hepatic encephalopathy (MHE) disease was developed." | 3.83 | Nano optical sensor binuclear Pt-2-pyrazinecarboxylic acid -bipyridine for enhancement of the efficiency of 3-nitrotyrosine biomarker for early diagnosis of liver cirrhosis with minimal hepatic encephalopathy. ( Al-Radadi, NS; Attia, MS, 2016) |
| "Pyrazinamide (PZA) is an important drug in the treatment of tuberculosis." | 1.38 | A new approach for pyrazinamide susceptibility testing in Mycobacterium tuberculosis. ( Cotrina, M; Fuentes, P; Gilman, RH; Gutierrez, A; Kirwan, D; Loli, S; Sheen, P; Zimic, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aono, A | 1 |
| Chikamatsu, K | 1 |
| Yamada, H | 1 |
| Igarashi, Y | 1 |
| Murase, Y | 1 |
| Takaki, A | 1 |
| Mitarai, S | 1 |
| Khan, MT | 1 |
| Malik, SI | 1 |
| Ali, S | 1 |
| Masood, N | 1 |
| Nadeem, T | 1 |
| Khan, AS | 1 |
| Afzal, MT | 1 |
| Attia, MS | 1 |
| Al-Radadi, NS | 1 |
| Zimic, M | 1 |
| Loli, S | 1 |
| Gilman, RH | 1 |
| Gutierrez, A | 1 |
| Fuentes, P | 1 |
| Cotrina, M | 1 |
| Kirwan, D | 1 |
| Sheen, P | 1 |
4 other studies available for pyrazinoic acid and Sensitivity and Specificity
| Article | Year |
|---|---|
A simplified pyrazinamidase test for pyrazinamide drug susceptibility in Mycobacterium tuberculosis.
Topics: Amidohydrolases; Antitubercular Agents; Culture Media; Diagnostic Tests, Routine; Drug Resistance, B | 2018 |
Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan.
Topics: Adolescent; Adult; Aged; Amidohydrolases; Antitubercular Agents; Child; Drug Resistance, Bacterial; | 2019 |
Nano optical sensor binuclear Pt-2-pyrazinecarboxylic acid -bipyridine for enhancement of the efficiency of 3-nitrotyrosine biomarker for early diagnosis of liver cirrhosis with minimal hepatic encephalopathy.
Topics: Adult; Biomarkers; Early Diagnosis; Equipment Design; Equipment Failure Analysis; Female; Hepatic En | 2016 |
A new approach for pyrazinamide susceptibility testing in Mycobacterium tuberculosis.
Topics: Antitubercular Agents; Biological Transport; Biotransformation; Drug Resistance, Bacterial; Humans; | 2012 |