inositol has been researched along with Sensitivity and Specificity in 65 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This project was designed to compare differences in brain proton spectra between children and adolescents with bipolar disorder (BPD) and gender and age-matched normal controls, and to measure changes in myo-inositol levels following lithium therapy, utilizing in vivo proton magnetic resonance spectroscopy (1H MRS)." | 9.09 | Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder. ( Belin, T; Davanzo, P; McCracken, J; Oshiro, T; Strober, M; Thomas, MA; Yue, K, 2001) |
| "We measured urinary myo-inositol enzymatically before and 2 h after a 75-g oral glucose tolerance test in 564 volunteers, who were divided into four groups [normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes mellitus (DM)]." | 7.72 | A study of urinary myo-inositol as a sensitive marker of glucose intolerance. ( Katsura, Y; Kawazu, S; Kure, M; Matsuoka, T; Noritake, M; Sarashina, G; Shiomi, H; Takahashi, M; Tominaga, M; Tsuboi, I; Yamagata, F; Yamakoshi, M, 2004) |
| "This project was designed to compare differences in brain proton spectra between children and adolescents with bipolar disorder (BPD) and gender and age-matched normal controls, and to measure changes in myo-inositol levels following lithium therapy, utilizing in vivo proton magnetic resonance spectroscopy (1H MRS)." | 5.09 | Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder. ( Belin, T; Davanzo, P; McCracken, J; Oshiro, T; Strober, M; Thomas, MA; Yue, K, 2001) |
| "Myo-inositol (MI) deficiency is associated with an increased risk for neural tube defects (NTDs), mental disorders and metabolic diseases." | 3.83 | Quantification of plasma myo-inositol using gas chromatography-mass spectrometry. ( Guo, J; Niu, B; Shi, Y; Wang, J; Xu, C; Zhang, F; Zhang, T; Zhong, R, 2016) |
| "We measured urinary myo-inositol enzymatically before and 2 h after a 75-g oral glucose tolerance test in 564 volunteers, who were divided into four groups [normal glucose tolerance (NGT), impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes mellitus (DM)]." | 3.72 | A study of urinary myo-inositol as a sensitive marker of glucose intolerance. ( Katsura, Y; Kawazu, S; Kure, M; Matsuoka, T; Noritake, M; Sarashina, G; Shiomi, H; Takahashi, M; Tominaga, M; Tsuboi, I; Yamagata, F; Yamakoshi, M, 2004) |
| " MRS of normal brain parenchyma displays 4 main metabolites: N-acetyl aspartate (neuronal marker), creatine (cellular density marker), choline (membrane activity marker) and myoinositol (glial marker); pathological processes lead to variations of the level of these metabolites and/or the appearance of abnormal metabolites (lactate), following different patterns according to pathological process involved: glioma, meningioma, metastasis, bacterial or toxoplasmic abscess, radionecrosis." | 3.71 | [Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors]. ( Confort-Gouny, S; Cozzone, PJ; Dufour, H; Galanaud, D; Le Fur, Y; Nicoli, F; Peragut, JC; Ranjeva, JP; Roche, P; Viout, P, 2002) |
| "To evaluate cerebral biochemical abnormalities in patients with frontotemporal dementia and Alzheimer disease and to determine whether proton (hydrogen-1) magnetic resonance (MR) spectroscopy can help differentiate among these two patient groups and healthy (control) subjects." | 3.69 | Frontotemporal dementia and early Alzheimer disease: differentiation with frontal lobe H-1 MR spectroscopy. ( Chang, L; Ernst, T; Mehringer, CM; Melchor, R, 1997) |
| "Dementia was an independent predictor of metabolite values." | 2.73 | Magnetic resonance spectroscopy performance for detection of dementia, Alzheimer's disease and mild cognitive impairment in a community-based survey. ( Antúnez, C; Carles, R; Fortuna, L; García Santos, JM; Gavrila, D; Jiménez Veiga, J; Navarro, C; Parrilla, G; Salmerón, D; Tormo, MJ; Torres del Río, S, 2008) |
| "Despite promising new therapies, bipolar depression remains difficult to treat." | 2.72 | Inositol augmentation of lithium or valproate for bipolar depression. ( Culhane, M; Demopulos, C; Eden Evins, A; Grandin, LD; Nierenberg, AA; Ogutha, J; Sachs, GS; Yovel, I, 2006) |
| "The validamycin A residue was extracted with methanol-water (9/1, v/v) or methanol by vortex, and a HLB solid-phase extraction cartridge was used for cleaning up the extracts." | 1.42 | Determination of validamycin A in agricultural food samples by solid-phase extraction combined with liquid chromatography-atmospheric pressure chemical ionisation-tandem mass spectrometry. ( Han, C; Shen, Y; Tian, Z; Wang, C; Xu, D; Zhang, Z, 2015) |
| "Myo-inositol plays key physiological functions, necessitating development of methodology for quantification in biological matrices." | 1.37 | Quantitative analysis of myo-inositol in urine, blood and nutritional supplements by high-performance liquid chromatography tandem mass spectrometry. ( Burren, KA; Copp, AJ; Greene, ND; Leung, KY; Mills, K, 2011) |
| "Choline/creatine was also significantly elevated in the left hippocampus-amygdala and cerebellar regions of children with autism spectrum disorder." | 1.35 | 1H-magnetic resonance spectroscopy markers of cognitive and language ability in clinical subtypes of autism spectrum disorders. ( Azizian, A; DeVincent, C; Gabis, L; Kesner-Baruch, Y; Pomeroy, J; Roche, P; Tudorica, A, 2008) |
| "The association with spina bifida was expressed by the ratio of geometric means and by odds ratios and 95% CI for a cutoff value at the extreme 10th percentile of the control group." | 1.32 | Maternal myo-inositol, glucose, and zinc status is associated with the risk of offspring with spina bifida. ( Franke, B; Groenen, PM; Mariman, EC; Peer, PG; Steegers-Theunissen, RP; Swinkels, DW; Wevers, RA, 2003) |
| "Myo-inositol is a strongly coupled system and resonates at four chemical shift positions." | 1.32 | A comparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brain. ( Hurd, R; Nelson, S; Sailasuta, N; Srinivasan, R; Vigneron, D, 2004) |
| "Mycothiol (MSH) is a glycosylated derivative of N-acetylcysteine that may have antioxidant functions in mycobacteria and other actinomycetes." | 1.30 | An immunoassay for the detection and quantitative determination of mycothiol. ( Davis, C; Fahey, RC; Newton, GL; Unson, MD, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.54) | 18.7374 |
| 1990's | 10 (15.38) | 18.2507 |
| 2000's | 31 (47.69) | 29.6817 |
| 2010's | 22 (33.85) | 24.3611 |
| 2020's | 1 (1.54) | 2.80 |
| Authors | Studies |
|---|---|
| Peña-Bautista, C | 1 |
| Torres-Cuevas, I | 1 |
| Baquero, M | 1 |
| Ferrer, I | 1 |
| García, L | 1 |
| Vento, M | 1 |
| Cháfer-Pericás, C | 1 |
| Zeitoun, H | 1 |
| Bahey-El-Din, M | 1 |
| Kassem, MA | 1 |
| Aboushleib, HM | 1 |
| Nagashima, H | 1 |
| Sasayama, T | 1 |
| Tanaka, K | 1 |
| Kyotani, K | 1 |
| Sato, N | 1 |
| Maeyama, M | 1 |
| Kohta, M | 1 |
| Sakata, J | 1 |
| Yamamoto, Y | 1 |
| Hosoda, K | 1 |
| Itoh, T | 1 |
| Sasaki, R | 1 |
| Kohmura, E | 1 |
| Xin, L | 1 |
| Gambarota, G | 1 |
| Cudalbu, C | 1 |
| Mlynárik, V | 1 |
| Gruetter, R | 2 |
| Ding, XQ | 1 |
| Maudsley, AA | 1 |
| Sabati, M | 1 |
| Sheriff, S | 1 |
| Dellani, PR | 1 |
| Lanfermann, H | 1 |
| Sarkar, BK | 1 |
| Chakraborty, C | 1 |
| Sharma, AR | 1 |
| Bae, KJ | 1 |
| Sharma, G | 1 |
| Doss, GP | 1 |
| Dutta, D | 1 |
| Ding, S | 1 |
| Ganbold, B | 1 |
| Nam, JS | 1 |
| Lee, SS | 1 |
| Wang, C | 1 |
| Zhang, Z | 1 |
| Shen, Y | 1 |
| Tian, Z | 1 |
| Xu, D | 1 |
| Han, C | 1 |
| Öz, G | 1 |
| Kittelson, E | 1 |
| Demirgöz, D | 1 |
| Rainwater, O | 1 |
| Eberly, LE | 1 |
| Orr, HT | 1 |
| Clark, HB | 1 |
| Guo, J | 1 |
| Shi, Y | 1 |
| Xu, C | 1 |
| Zhong, R | 1 |
| Zhang, F | 1 |
| Zhang, T | 1 |
| Niu, B | 1 |
| Wang, J | 1 |
| Jiménez-Xarrié, E | 1 |
| Davila, M | 1 |
| Candiota, AP | 1 |
| Delgado-Mederos, R | 1 |
| Ortega-Martorell, S | 1 |
| Julià-Sapé, M | 1 |
| Arús, C | 1 |
| Martí-Fàbregas, J | 1 |
| García Santos, JM | 1 |
| Gavrila, D | 1 |
| Antúnez, C | 1 |
| Tormo, MJ | 1 |
| Salmerón, D | 1 |
| Carles, R | 1 |
| Jiménez Veiga, J | 1 |
| Parrilla, G | 1 |
| Torres del Río, S | 1 |
| Fortuna, L | 1 |
| Navarro, C | 1 |
| Watanabe, T | 1 |
| Shiino, A | 1 |
| Akiguchi, I | 1 |
| Bernabeu, A | 1 |
| Alfaro, A | 1 |
| García, M | 1 |
| Fernández, E | 1 |
| Iwasaki, Y | 1 |
| Masayama, A | 1 |
| Mori, A | 1 |
| Ikeda, C | 1 |
| Nakano, H | 1 |
| Srinivasan, R | 2 |
| Phillips, JJ | 1 |
| Vandenberg, SR | 1 |
| Polley, MY | 1 |
| Bourne, G | 1 |
| Au, A | 1 |
| Pirzkall, A | 1 |
| Cha, S | 1 |
| Chang, SM | 1 |
| Nelson, SJ | 1 |
| Yakoub, D | 1 |
| Keun, HC | 1 |
| Goldin, R | 1 |
| Hanna, GB | 1 |
| Hancu, I | 1 |
| Gillen, R | 1 |
| Cowan, J | 1 |
| Zimmerman, EA | 1 |
| Kirov, II | 1 |
| George, IC | 1 |
| Jayawickrama, N | 1 |
| Babb, JS | 1 |
| Perry, NN | 1 |
| Gonen, O | 1 |
| Kim, BH | 1 |
| Park, JY | 1 |
| Jang, JB | 1 |
| Moon, DC | 1 |
| Ganji, SK | 1 |
| Banerjee, A | 1 |
| Patel, AM | 1 |
| Zhao, YD | 1 |
| Dimitrov, IE | 1 |
| Browning, JD | 1 |
| Brown, ES | 1 |
| Maher, EA | 1 |
| Choi, C | 1 |
| Leung, KY | 1 |
| Mills, K | 1 |
| Burren, KA | 1 |
| Copp, AJ | 1 |
| Greene, ND | 1 |
| Zheng, P | 1 |
| Gao, HC | 1 |
| Li, Q | 1 |
| Shao, WH | 1 |
| Zhang, ML | 1 |
| Cheng, K | 1 |
| Yang, DY | 1 |
| Fan, SH | 1 |
| Chen, L | 1 |
| Fang, L | 1 |
| Xie, P | 1 |
| Cheng, VC | 1 |
| Yam, WC | 1 |
| Tsang, LL | 1 |
| Yau, MC | 1 |
| Siu, GK | 1 |
| Wong, SC | 1 |
| Chan, JF | 1 |
| To, KK | 1 |
| Tse, H | 1 |
| Hung, IF | 1 |
| Tai, JW | 1 |
| Ho, PL | 1 |
| Yuen, KY | 1 |
| Bathena, SP | 1 |
| Huang, J | 1 |
| Epstein, AA | 1 |
| Gendelman, HE | 1 |
| Boska, MD | 1 |
| Alnouti, Y | 1 |
| Sun, T | 1 |
| Wetzel, SJ | 1 |
| Johnson, ME | 1 |
| Surlow, BA | 1 |
| Patton-Vogt, J | 1 |
| Hock, A | 1 |
| MacMillan, EL | 1 |
| Fuchs, A | 1 |
| Kreis, R | 2 |
| Boesiger, P | 1 |
| Kollias, SS | 1 |
| Henning, A | 1 |
| Gutzeit, A | 1 |
| Meier, D | 1 |
| Froehlich, JM | 1 |
| Hergan, K | 1 |
| Kos, S | 1 |
| V Weymarn, C | 1 |
| Lutz, K | 1 |
| Ettlin, D | 1 |
| Binkert, CA | 1 |
| Mutschler, J | 1 |
| Sartoretti-Schefer, S | 1 |
| Brügger, M | 1 |
| Binesh, N | 1 |
| Yue, K | 2 |
| Fairbanks, L | 1 |
| Thomas, MA | 2 |
| Hofmann, L | 1 |
| Kuhlmann, B | 1 |
| Boesch, C | 1 |
| Bossi, E | 1 |
| Hüppi, PS | 1 |
| Galanaud, D | 2 |
| Dormont, D | 1 |
| Grabli, D | 1 |
| Charles, P | 1 |
| Hauw, JJ | 1 |
| Lubetzki, C | 1 |
| Brandel, JP | 1 |
| Marsault, C | 1 |
| Cozzone, PJ | 2 |
| Yamakoshi, M | 2 |
| Takahashi, M | 3 |
| Kouzuma, T | 2 |
| Imamura, S | 1 |
| Tsuboi, I | 2 |
| Kawazu, S | 2 |
| Yamagata, F | 2 |
| Tominaga, M | 2 |
| Noritake, M | 2 |
| Rijpkema, M | 1 |
| Schuuring, J | 1 |
| van der Meulen, Y | 1 |
| van der Graaf, M | 2 |
| Bernsen, H | 1 |
| Boerman, R | 1 |
| van der Kogel, A | 1 |
| Heerschap, A | 2 |
| Nicoli, F | 1 |
| Le Fur, Y | 1 |
| Roche, P | 2 |
| Confort-Gouny, S | 1 |
| Dufour, H | 1 |
| Ranjeva, JP | 1 |
| Peragut, JC | 1 |
| Viout, P | 1 |
| SCHOPFER, WH | 1 |
| POSTERNAK, T | 1 |
| Groenen, PM | 1 |
| Peer, PG | 1 |
| Wevers, RA | 1 |
| Swinkels, DW | 1 |
| Franke, B | 1 |
| Mariman, EC | 1 |
| Steegers-Theunissen, RP | 1 |
| Simonetti, AW | 1 |
| Melssen, WJ | 1 |
| Postma, GJ | 1 |
| Buydens, LM | 1 |
| Bachert, P | 1 |
| Schröder, L | 1 |
| Perelló, J | 1 |
| Isern, B | 1 |
| Costa-Bauzá, A | 1 |
| Grases, F | 1 |
| Vigneron, D | 1 |
| Sailasuta, N | 1 |
| Hurd, R | 1 |
| Nelson, S | 1 |
| Sarashina, G | 1 |
| Kure, M | 1 |
| Katsura, Y | 1 |
| Shiomi, H | 1 |
| Matsuoka, T | 1 |
| Kaiser, LG | 1 |
| Schuff, N | 1 |
| Cashdollar, N | 1 |
| Weiner, MW | 1 |
| Eden Evins, A | 1 |
| Demopulos, C | 1 |
| Yovel, I | 1 |
| Culhane, M | 1 |
| Ogutha, J | 1 |
| Grandin, LD | 1 |
| Nierenberg, AA | 1 |
| Sachs, GS | 1 |
| Xue, YP | 1 |
| Zheng, YG | 1 |
| Chen, XL | 1 |
| Shen, YC | 1 |
| Shaltiel, G | 1 |
| Dalton, EC | 1 |
| Belmaker, RH | 1 |
| Harwood, AJ | 1 |
| Agam, G | 1 |
| Harris, LM | 1 |
| Davies, N | 1 |
| Macpherson, L | 1 |
| Foster, K | 1 |
| Lateef, S | 1 |
| Natarajan, K | 1 |
| Sgouros, S | 1 |
| Brundler, MA | 1 |
| Arvanitis, TN | 1 |
| Grundy, RG | 1 |
| Peet, AC | 1 |
| Gottschalk, M | 1 |
| Lamalle, L | 1 |
| Segebarth, C | 1 |
| Brunetti-Pierri, N | 1 |
| Bhattacharjee, MB | 1 |
| Wang, ZJ | 1 |
| Wenger, DA | 1 |
| Potocki, L | 1 |
| Hunter, J | 1 |
| Scaglia, F | 1 |
| Gabis, L | 1 |
| Azizian, A | 1 |
| DeVincent, C | 1 |
| Tudorica, A | 1 |
| Kesner-Baruch, Y | 1 |
| Pomeroy, J | 1 |
| Chang, L | 2 |
| Miller, BL | 1 |
| McBride, D | 1 |
| Cornford, M | 1 |
| Oropilla, G | 1 |
| Buchthal, S | 1 |
| Chiang, F | 1 |
| Aronow, H | 1 |
| Beck, CK | 1 |
| Ernst, T | 2 |
| Resnick, SM | 1 |
| Costa, PT | 1 |
| Shonk, TK | 1 |
| Moats, RA | 1 |
| Gifford, P | 1 |
| Michaelis, T | 1 |
| Mandigo, JC | 1 |
| Izumi, J | 1 |
| Ross, BD | 1 |
| Piérard, C | 1 |
| Satabin, P | 1 |
| Lagarde, D | 1 |
| Barrère, B | 1 |
| Guezennec, CY | 1 |
| Menu, JP | 1 |
| Pérès, M | 1 |
| Melchor, R | 1 |
| Mehringer, CM | 1 |
| Hennig, J | 1 |
| Thiel, T | 1 |
| Speck, O | 1 |
| Rodríguez-Díaz, M | 1 |
| Garzón, J | 1 |
| Sánchez-Blázquez, P | 1 |
| Unson, MD | 2 |
| Newton, GL | 2 |
| Davis, C | 1 |
| Fahey, RC | 2 |
| Arnold, KF | 1 |
| Davis, CE | 1 |
| O'Neill, RB | 1 |
| Dillon, SA | 1 |
| Morgan, PM | 1 |
| Choi, IY | 1 |
| Tkác, I | 1 |
| McLean, MA | 1 |
| Woermann, FG | 1 |
| Barker, GJ | 1 |
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| Griffiths, JR | 1 |
| Davanzo, P | 1 |
| Oshiro, T | 1 |
| Belin, T | 1 |
| Strober, M | 1 |
| McCracken, J | 1 |
| Lee, CW | 1 |
| Lee, JH | 1 |
| Lim, TH | 1 |
| Yang, HS | 1 |
| Hong, MK | 1 |
| Song, JK | 1 |
| Park, SW | 1 |
| Park, SJ | 1 |
| Kim, JJ | 1 |
| Endoh, T | 1 |
| Kaneko, R | 1 |
| Ura, N | 1 |
| Shimamoto, K | 1 |
| Watanabe, N | 1 |
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| Rozenthal, M | 1 |
| Oliveira, AC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study for the Development of a Cortical Visual Neuroprosthesis for the Blind Based on Intracortical Microelectrodes[NCT02983370] | 5 participants (Anticipated) | Interventional | 2019-10-01 | Recruiting | |||
| Muscle Fat Compartments and Turnover as Determinant of Insulin Sensitivity - the MISTY Study[NCT03065140] | 50 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| Role of Glutamate-mediate Excitotoxicity in Invasion and Progression Processes of Glioblastoma Multiforme[NCT05775458] | 50 participants (Anticipated) | Observational | 2020-06-01 | Recruiting | |||
| Inositol for Comorbid Anxiety in Children and Adolescents With Bipolar Disorder[NCT02811133] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2023-08-31 | Withdrawn (stopped due to Funding terminated) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for inositol and Sensitivity and Specificity
| Article | Year |
|---|---|
Novel biomarker for prostate cancer diagnosis by MRS.
Topics: Biomarkers, Tumor; Choline; Citric Acid; Creatine; Humans; Inositol; Magnetic Resonance Spectroscopy | 2014 |
[Alzheimer's disease and magnetic resonance spectroscopy of the hippocampus].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Case-Control Studies; Choline; Creatine; | 2001 |
11 trials available for inositol and Sensitivity and Specificity
| Article | Year |
|---|---|
Magnetic resonance spectroscopy performance for detection of dementia, Alzheimer's disease and mild cognitive impairment in a community-based survey.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Brain; Choline; Cognition Disorders; Crea | 2008 |
Absolute quantification in proton magnetic resonance spectroscopy is superior to relative ratio to discriminate Alzheimer's disease from Binswanger's disease.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Choline; Creatine; Dementia, Vascular; Diagnosis, Differenti | 2008 |
Reproducibility of localized 2D correlated MR spectroscopy.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Brain Chemistry; Brain Mapping; Female; Glutamate | 2002 |
Brain metabolite composition during early human brain development as measured by quantitative in vivo 1H magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Choline; Embryonic and Fetal Development; Female; Gestational | 2002 |
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging.
Topics: Adult; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Dipeptides; Female; Glutamic Acid | 2003 |
Scyllo-inositol in normal aging human brain: 1H magnetic resonance spectroscopy study at 4 Tesla.
Topics: Adaptation, Physiological; Adult; Aged; Aging; Brain; Female; Humans; Inositol; Internal Capsule; Ma | 2005 |
Inositol augmentation of lithium or valproate for bipolar depression.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Brief Psychiatric Rating Scale | 2006 |
Probable Alzheimer disease: diagnosis with proton MR spectroscopy.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Brain Diseases, Metabolic; Creatine; Dementia; Diagno | 1995 |
Quantitative analysis of short echo time (1)H-MRSI of cerebral gray and white matter.
Topics: Adult; Aspartic Acid; Brain; Brain Chemistry; Calibration; Cerebrospinal Fluid; Choline; Creatine; D | 2000 |
Decreased anterior cingulate myo-inositol/creatine spectroscopy resonance with lithium treatment in children with bipolar disorder.
Topics: Adolescent; Area Under Curve; Aspartic Acid; Bipolar Disorder; Child; Creatine; Demography; Drug Adm | 2001 |
Prognostic significance of cerebral metabolic abnormalities in patients with congestive heart failure.
Topics: Adult; Aspartic Acid; Brain; Brain Diseases, Metabolic; Choline; Creatine; Female; Follow-Up Studies | 2001 |
52 other studies available for inositol and Sensitivity and Specificity
| Article | Year |
|---|---|
Early neurotransmission impairment in non-invasive Alzheimer Disease detection.
Topics: Acetylcholine; Aged; Alzheimer Disease; Amino Acids; Biomarkers; Cognitive Dysfunction; Creatine; Fe | 2020 |
Mycothiol acetyltransferase (Rv0819) of Mycobacterium tuberculosis is a potential biomarker for direct diagnosis of tuberculosis using patient serum specimens.
Topics: Acetyltransferases; Adult; Aged; Antigens, Bacterial; Biomarkers; Cloning, Molecular; Cysteine; Earl | 2017 |
Myo-inositol concentration in MR spectroscopy for differentiating high grade glioma from primary central nervous system lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; Glioma; Humans; Imag | 2018 |
Single spin-echo T2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain.
Topics: Animals; Brain; Choline; Creatine; Glutamic Acid; Inositol; Magnetic Resonance Spectroscopy; Male; P | 2013 |
Reproducibility and reliability of short-TE whole-brain MR spectroscopic imaging of human brain at 3T.
Topics: Adult; Algorithms; Aspartic Acid; Brain; Choline; Creatine; Female; Glutamic Acid; Glutamine; Humans | 2015 |
Determination of validamycin A in agricultural food samples by solid-phase extraction combined with liquid chromatography-atmospheric pressure chemical ionisation-tandem mass spectrometry.
Topics: Atmospheric Pressure; Chromatography, High Pressure Liquid; Crops, Agricultural; Inositol; Reproduci | 2015 |
Assessing recovery from neurodegeneration in spinocerebellar ataxia 1: Comparison of in vivo magnetic resonance spectroscopy with motor testing, gene expression and histology.
Topics: Animals; Area Under Curve; Aspartic Acid; Ataxin-1; Cerebellum; Doxycycline; Gene Expression; Humans | 2015 |
Quantification of plasma myo-inositol using gas chromatography-mass spectrometry.
Topics: Anencephaly; Female; Gas Chromatography-Mass Spectrometry; Humans; Inositol; Male; Mass Screening; N | 2016 |
Brain metabolic pattern analysis using a magnetic resonance spectra classification software in experimental stroke.
Topics: Animals; Brain; Brain Ischemia; Creatine; Image Processing, Computer-Assisted; Inositol; Lactic Acid | 2017 |
Proton magnetic resonance spectroscopy (1H-MRS) reveals the presence of elevated myo-inositol in the occipital cortex of blind subjects.
Topics: Adult; Aged; Biomarkers; Blindness; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Male; | 2009 |
Composition analysis of positional isomers of phosphatidylinositol by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Inositol; Isomerism; Phenylcarbamates; Phosphatidylcholines; P | 2009 |
Ex vivo MR spectroscopic measure differentiates tumor from treatment effects in GBM.
Topics: Biomarkers, Tumor; Brain Neoplasms; Choline; Glioblastoma; Humans; Image Interpretation, Computer-As | 2010 |
Metabolic profiling detects field effects in nondysplastic tissue from esophageal cancer patients.
Topics: Adenocarcinoma; Barrett Esophagus; Cell Transformation, Neoplastic; Diagnosis, Differential; Esophag | 2010 |
Improved myo-inositol detection through Carr-Purcell PRESS: a tool for more sensitive mild cognitive impairment diagnosis.
Topics: Aged; Analysis of Variance; Aspartic Acid; Case-Control Studies; Cognition Disorders; Discriminant A | 2011 |
Longitudinal inter- and intra-individual human brain metabolic quantification over 3 years with proton MR spectroscopy at 3 T.
Topics: Aging; Algorithms; Aspartic Acid; Brain; Choline; Creatine; Humans; Inositol; Longitudinal Studies; | 2012 |
LC-MS/MS method for the quantification of myo- and chiro-inositol as the urinary biomarkers of insulin resistance in human urine.
Topics: Biomarkers; Chromatography, Liquid; Humans; Inositol; Insulin Resistance; Sensitivity and Specificit | 2012 |
T2 measurement of J-coupled metabolites in the human brain at 3T.
Topics: Adult; Aspartic Acid; Brain; Creatinine; Glutamic Acid; Humans; Inositol; Magnetic Resonance Imaging | 2012 |
Quantitative analysis of myo-inositol in urine, blood and nutritional supplements by high-performance liquid chromatography tandem mass spectrometry.
Topics: Adult; Chromatography, High Pressure Liquid; Dietary Supplements; Glucose; Humans; Inositol; Linear | 2011 |
Plasma metabonomics as a novel diagnostic approach for major depressive disorder.
Topics: Acetates; Adult; Amino Acids; Biomarkers; Case-Control Studies; Creatine; Creatinine; Depressive Dis | 2012 |
Epidemiology of Klebsiella oxytoca-associated diarrhea detected by Simmons citrate agar supplemented with inositol, tryptophan, and bile salts.
Topics: Adolescent; Adult; Agar; Aged; Aged, 80 and over; Bacteriological Techniques; Bile Acids and Salts; | 2012 |
Rapid and reliable quantitation of amino acids and myo-inositol in mouse brain by high performance liquid chromatography and tandem mass spectrometry.
Topics: Amino Acids; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Hydrophobic and Hydroph | 2012 |
Development and validation of a hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the quantification of lipid-related extracellular metabolites in Saccharomyces cerevisiae.
Topics: Choline; Chromatography, Liquid; Fungal Proteins; Gene Deletion; Glycerophospholipids; Hydrophobic a | 2012 |
Non-water-suppressed proton MR spectroscopy improves spectral quality in the human spinal cord.
Topics: Adult; Algorithms; Aspartic Acid; Body Water; Choline; Creatine; Female; Humans; Inositol; Magnetic | 2013 |
Differential NMR spectroscopy reactions of anterior/posterior and right/left insular subdivisions due to acute dental pain.
Topics: Acute Pain; Adult; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Glutamic Acid; Glutamine; Humans | 2013 |
MR spectroscopic pulvinar sign in a case of variant Creutzfeldt-Jakob disease.
Topics: Adult; Aspartic Acid; Biopsy; Case-Control Studies; Choline; Creatine; Creutzfeldt-Jakob Syndrome; F | 2002 |
Determination of urinary myo-inositol concentration by an improved enzymatic cycling method using myo-inositol dehydrogenase from Flavobacterium sp.
Topics: Adult; Female; Flavobacterium; Humans; Inositol; Male; Middle Aged; Phosphoric Monoester Hydrolases; | 2003 |
[Contribution of magnetic resonance spectrometry to the diagnosis of intracranial tumors].
Topics: Aspartic Acid; Biomarkers; Brain Abscess; Brain Neoplasms; Choline; Computer Graphics; Creatine; Dia | 2002 |
[On the specificity of the action of meso-inositol and on the purification of D-inositol].
Topics: Inositol; Sensitivity and Specificity | 1959 |
Maternal myo-inositol, glucose, and zinc status is associated with the risk of offspring with spina bifida.
Topics: Adult; Biomarkers; Blood Glucose; Case-Control Studies; Child, Preschool; Confidence Intervals; Fema | 2003 |
A chemometric approach for brain tumor classification using magnetic resonance imaging and spectroscopy.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Neoplasms; Cerebrospinal Fluid; Choline; Creatine; Disc | 2003 |
[Magnetic resonance imaging spectroscopy. Part 1: Basics].
Topics: Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Choline; Energy Metabolism; Humans; Image Enh | 2003 |
Determination of myo-inositol in biological samples by liquid chromatography-mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Humans; Inositol; Mass Spectrometry; Reproducibility of Result | 2004 |
A comparative study of myo-inositol quantification using LCmodel at 1.5 T and 3.0 T with 3 D 1H proton spectroscopic imaging of the human brain.
Topics: Aspartic Acid; Brain; Dipeptides; Female; Humans; Hydrogen; Inositol; Magnetic Resonance Spectroscop | 2004 |
A study of urinary myo-inositol as a sensitive marker of glucose intolerance.
Topics: Adult; Age Factors; Biomarkers; Case-Control Studies; Female; Glucose Intolerance; Humans; Inositol; | 2004 |
Quantitative determination of valienamine and validamine by thin-layer chromatography.
Topics: Chromatography, Thin Layer; Cyclohexenes; Glycoside Hydrolase Inhibitors; Hexosamines; Inositol; Rep | 2007 |
Specificity of mood stabilizer action on neuronal growth cones.
Topics: Animals; Animals, Newborn; Ganglia, Spinal; Inositol; Lithium Compounds; Psychotropic Drugs; Rats; R | 2007 |
The use of short-echo-time 1H MRS for childhood cerebellar tumours prior to histopathological diagnosis.
Topics: Aspartic Acid; Biomarkers, Tumor; Cerebellar Neoplasms; Cerebellum; Child; Choline; Creatine; Humans | 2007 |
Short-TE localised 1H MRS of the human brain at 3 T: quantification of the metabolite signals using two approaches to account for macromolecular signal contributions.
Topics: Adult; Aspartic Acid; Body Water; Brain; Choline; Creatine; Echo-Planar Imaging; Female; Glucose; Gl | 2008 |
Brain proton magnetic resonance spectroscopy and neuromuscular pathology in a patient with GM1 gangliosidosis.
Topics: Aspartic Acid; Axons; Biomarkers; Brain; Female; Gangliosidosis, GM1; Gliosis; Humans; Infant; Inosi | 2008 |
1H-magnetic resonance spectroscopy markers of cognitive and language ability in clinical subtypes of autism spectrum disorders.
Topics: Adolescent; Amygdala; Analysis of Variance; Aspartic Acid; Asperger Syndrome; Autistic Disorder; Bio | 2008 |
Brain lesions in patients with AIDS: H-1 MR spectroscopy.
Topics: Abscess; Adult; AIDS Dementia Complex; Aspartic Acid; Brain Diseases; Brain Neoplasms; Choline; Crea | 1995 |
Comments on use of H-1 MR spectroscopy for diagnosis of probable Alzheimer disease.
Topics: Aged; Alzheimer Disease; Aspartic Acid; Brain; Creatine; Humans; Inositol; Magnetic Resonance Spectr | 1995 |
Effects of a vigilance-enhancing drug, modafinil, on rat brain metabolism: a 2D COSY 1H-NMR study.
Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Cognition; C | 1995 |
Frontotemporal dementia and early Alzheimer disease: differentiation with frontal lobe H-1 MR spectroscopy.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aspartic Acid; Dementia; Discriminant Analysis; Female; | 1997 |
Improved sensitivity to overlapping multiplet signals in in vivo proton spectroscopy using a multiecho volume selective (CPRESS) experiment.
Topics: Alanine; Aspartic Acid; Brain; Choline; Creatine; gamma-Aminobutyric Acid; Humans; Inositol; Magneti | 1997 |
The delta2-opioid receptor subtype stimulates phosphoinositide metabolism in mouse periaqueductal gray matter.
Topics: Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Inositol | 1998 |
An immunoassay for the detection and quantitative determination of mycothiol.
Topics: Animals; Antibodies; Chromatography, High Pressure Liquid; Cysteine; Disaccharides; Enterococcus fae | 1998 |
Improved methods for immunoassay of mycothiol.
Topics: Animals; Antibodies; Antibody Specificity; Biotinylation; Cerebrospinal Fluid; Cysteine; Disaccharid | 1999 |
A coupled enzyme assay for myo-inositol.
Topics: Dihydrolipoamide Dehydrogenase; Inositol; NAD; Oxidation-Reduction; Sensitivity and Specificity; Spe | 1998 |
Single-shot, three-dimensional "non-echo" localization method for in vivo NMR spectroscopy.
Topics: Acetates; Animals; Aspartic Acid; Brain Chemistry; Calibration; Carbon Isotopes; Evaluation Studies | 2000 |
Sensitivity of quantitative (1)H magnetic resonance spectroscopy of the brain in detecting early neuronal damage in systemic lupus erythematosus.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Brain Diseases; Case-Control Studies; Choline; Creatine; Fem | 2001 |
An enzymatic cycling method for the measurement of myo-inositol in biological samples.
Topics: Aged; Bacillus; Biochemistry; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Inositol; Male; NA | 2001 |