| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent. | 2.31 | 1 | 0 | isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | |
ascaridole
ascaridole: monoterpene endoperoxide with anthelmintic properties; structure given in first source. ascaridole : A p-menthane monoterpenoid that is p-menth-2-ene with a peroxy group across position 1 to 4. | 1.98 | 1 | 0 | organic heterobicyclic compound;
organic peroxide;
p-menthane monoterpenoid | antileishmanial agent;
antinematodal drug;
plant metabolite |
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46. | 7.41 | 1 | 0 | metal allergen;
nickel group element atom;
platinum group metal atom | |
alkenes
[no description available] | 2.6 | 1 | 0 | | |
artemisinin
(+)-artemisinin : A sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. | 5.01 | 14 | 0 | organic peroxide;
sesquiterpene lactone | antimalarial;
plant metabolite |
artemether
Artemether: An artemisinin derivative that is used in the treatment of MALARIA.. artemether : An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. | 7.44 | 2 | 0 | artemisinin derivative;
cyclic acetal;
organic peroxide;
semisynthetic derivative;
sesquiterpenoid | antimalarial |
artesunic acid
[no description available] | 2.31 | 1 | 0 | | |
sesquiterpenes
[no description available] | 3.11 | 5 | 0 | | |
artemotil
artemotil: structure given in first source; RN given refers to cpd without isomeric designation | 1.98 | 1 | 0 | artemisinin derivative | |
scopoletin
[no description available] | 8.44 | 2 | 0 | hydroxycoumarin | plant growth regulator;
plant metabolite |
dexmedetomidine
chrysoplenol D: potentiates the activity of berberine, artemisinin, and norfloxacine against S. aureus; isolated from Artemisa annua; structure in first source. 3',4',5-trihydroxy-3,6,7-trimethoxyflavone : A trimethoxyflavone that is the 3,6,7-trimethyl ether derivative of quercetagetin. | 2.21 | 1 | 0 | trihydroxyflavone;
trimethoxyflavone | antineoplastic agent;
metabolite |
eupatoriopicrine
[no description available] | 1.98 | 1 | 0 | germacranolide | |
casticin
casticin: from fruit of Vitex rotundifolia; structure in second source. casticin : A tetramethoxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6, 7 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii. | 2.21 | 1 | 0 | dihydroxyflavone;
tetramethoxyflavone | apoptosis inducer;
plant metabolite |
andrographolide
[no description available] | 7.31 | 1 | 0 | carbobicyclic compound;
gamma-lactone;
labdane diterpenoid;
primary alcohol;
secondary alcohol | anti-HIV agent;
anti-inflammatory drug;
antineoplastic agent;
metabolite |
licochalcone b
licochalcone B: isolated from Glycyrrhiza inflata; inhibits phosphorylation of NF-kappaB p65 in LPS signaling pathway; structure in first source | 7.31 | 1 | 0 | chalcones | |
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. | 7.6 | 1 | 0 | cysteinium | fundamental metabolite |
artenimol
artenimol: derivative of antimalarial drug artemisinin (quinghaosu) | 1.98 | 1 | 0 | | |
artemisitene
artemisitene: RN given for (3R-(3alpha,5abeta,6beta,8abeta,12beta,12aR*))-isomer; structure in first source | 2.49 | 2 | 0 | | |
artemisic acid
artemisic acid: isolated from Artemisia annua; MF: C28-H58-O; RN from Toxline. (+)-artemisinic acid : A monocarboxylic acid that is prop-2-enoic acid which is substituted at position 2 by a 4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group (the 1S,4R,4aS,8aR diastereoisomer). It is a sesquiterpenoid precursor of artemisinin, obtained from sweet wormwood, Artemisia annua. | 9.69 | 10 | 0 | carbobicyclic compound;
monocarboxylic acid;
octahydronaphthalenes;
sesquiterpenoid | metabolite |
dihydroartemisinic acid
dihydroartemisinic acid: structure in first source. dihydroartemisinic acid : A monocarboxylic acid that is propanoic acid substituted at position 2 by a (1S,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group. It is a sesquiterpenoid precursor of the antimalarial drug, artemisinin. | 2.08 | 1 | 0 | carbobicyclic compound;
monocarboxylic acid;
octahydronaphthalenes;
sesquiterpenoid | plant metabolite |
sodium artesunate
[no description available] | 1.98 | 1 | 0 | | |