Page last updated: 2024-08-07 12:49:46
Carbonic anhydrase 2
A vertebrate-type carbonic anhydrase 2 that is encoded in the genome of cow. [OMA:P00921, PRO:DNx]
Synonyms
EC 4.2.1.1;
Carbonate dehydratase II;
Carbonic anhydrase II;
CA-II
Research
Bioassay Publications (9)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (14)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| acetazolamide | Bos taurus (cattle) | IC50 | 0.7000 | 3 | 3 |
| acetazolamide | Bos taurus (cattle) | Ki | 0.1370 | 1 | 1 |
| sulfanilamide | Bos taurus (cattle) | Ki | 12.9850 | 1 | 2 |
| zonisamide | Bos taurus (cattle) | IC50 | 1.8600 | 1 | 1 |
| 4-toluenesulfonamide | Bos taurus (cattle) | Ki | 1.6467 | 1 | 2 |
| benzenesulfonamide | Bos taurus (cattle) | Ki | 3.8818 | 1 | 2 |
| carzenide | Bos taurus (cattle) | Ki | 0.1510 | 1 | 1 |
| 4-chlorobenzenesulfonamide | Bos taurus (cattle) | Ki | 0.5553 | 1 | 2 |
| 4-bromobenzenesulfonamide | Bos taurus (cattle) | Ki | 0.5553 | 1 | 2 |
| methanesulfonamide | Bos taurus (cattle) | IC50 | 0.6500 | 1 | 1 |
| betulinic acid methyl ester | Bos taurus (cattle) | Ki | 50.0000 | 1 | 1 |
| trifluoromethylsulfonamide | Bos taurus (cattle) | IC50 | 0.0020 | 1 | 1 |
| 3,4-Dichlorobenzenesulfonamide | Bos taurus (cattle) | Ki | 0.1523 | 1 | 2 |
| methyl ursolate | Bos taurus (cattle) | Ki | 10.0000 | 1 | 1 |
| 3-nitro-N-[(3-sulfamoylanilino)-sulfanylidenemethyl]benzamide | Bos taurus (cattle) | IC50 | 0.4900 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| sulfanilamide | Bos taurus (cattle) | Kd | 5.8800 | 1 | 1 |
| carzenide | Bos taurus (cattle) | Kd | 0.8900 | 1 | 1 |