ketanserin has been researched along with Sensitivity and Specificity in 3 studies
Ketanserin: A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
ketanserin : A member of the class of quinazolines that is quinazoline-2,4(1H,3H)-dione which is substituted at position 3 by a 2-[4-(p-fluorobenzoyl)piperidin-1-yl]ethyl group.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " During chronic administration, however, the alpha-1 blocking effects of KET are compensated for, and the reduction in blood pressure by day 7 of KET chronic administration is maintained predominantly by persistent blockade of 5HT2 receptors." | 1.29 | Differences in the acute and chronic antihypertensive mechanism of action of ketanserin in spontaneously hypertensive rats. ( Balasubramaniam, G; Lee, HS; Mah, SC, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yassen, A | 1 |
| Hanff, LM | 1 |
| Vulto, AG | 1 |
| MacLean, MR | 1 |
| Clayton, RA | 1 |
| Hillis, SW | 1 |
| McIntyre, PD | 1 |
| Peacock, AJ | 1 |
| Templeton, AG | 1 |
| Balasubramaniam, G | 1 |
| Lee, HS | 1 |
| Mah, SC | 1 |
3 other studies available for ketanserin and Sensitivity and Specificity
| Article | Year |
|---|---|
Simultaneous quantitative analysis of ketanserin and ketanserinol in plasma by RP-HPLC with fluorescence detection.
Topics: Calibration; Chromatography, High Pressure Liquid; Humans; Ketanserin; Reproducibility of Results; S | 2003 |
5-HT1-receptor-mediated vasoconstriction in bovine isolated pulmonary arteries: influences of vascular endothelium and tone.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cattle; Drug Interactions; Endothelium, Vascular; In | 1994 |
Differences in the acute and chronic antihypertensive mechanism of action of ketanserin in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Heart Rate; Hypertension; Infusions, Intraven | 1993 |