clioquinol has been researched along with Sensitivity and Specificity in 2 studies
Clioquinol: A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide.
5-chloro-7-iodoquinolin-8-ol : A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by chlorine and iodine, respectively. It has antibacterial and atifungal properties, and is used in creams for the treatment of skin infections. It has also been investigated as a chelator of copper and zinc ions for the possible treatment of Alzheimer's disease.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clioquinol was separated on a Nucleosil C18 300 mm x 3." | 1.33 | Determination of 5-chloro-7-iodo-8-quinolinol (clioquinol) in plasma and tissues of hamsters by high-performance liquid chromatography and electrochemical detection. ( Bareggi, SR; Bondiolotti, GP; Pirola, R; Pollera, C, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, BY | 1 |
| Toyama, BH | 1 |
| Wille, H | 1 |
| Colby, DW | 1 |
| Collins, SR | 1 |
| May, BC | 1 |
| Prusiner, SB | 1 |
| Weissman, J | 1 |
| Shoichet, BK | 1 |
| Bondiolotti, GP | 1 |
| Pollera, C | 1 |
| Pirola, R | 1 |
| Bareggi, SR | 1 |
2 other studies available for clioquinol and Sensitivity and Specificity
| Article | Year |
|---|---|
Small-molecule aggregates inhibit amyloid polymerization.
Topics: Acetophenones; Animals; Benzopyrans; beta-Lactamase Inhibitors; beta-Lactamases; Clioquinol; Congo R | 2008 |
Determination of 5-chloro-7-iodo-8-quinolinol (clioquinol) in plasma and tissues of hamsters by high-performance liquid chromatography and electrochemical detection.
Topics: Administration, Oral; Amebicides; Animals; Chromatography, High Pressure Liquid; Clioquinol; Criceti | 2006 |