An aldo-keto reductase family 1 member A1 that is encoded in the genome of pig. [OMA:P50578, PRO:DNx]
EC 1.1.1.2;
EC 1.1.1.33;
EC 1.1.1.372;
EC 1.1.1.54;
Alcohol dehydrogenase [NADP(+)];
Aldehyde reductase;
Glucuronate reductase;
1.1.1.19;
Glucuronolactone reductase;
1.1.1.20
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| ponalrestat | Sus scrofa (pig) | IC50 | 2.0000 | 1 | 1 |
| 3,5-dichlorosalicylic acid | Sus scrofa (pig) | IC50 | 11.3000 | 1 | 1 |
| tolrestat | Sus scrofa (pig) | IC50 | 1.3650 | 2 | 2 |
| al-01567 | Sus scrofa (pig) | IC50 | 0.0270 | 1 | 1 |
| fidarestat | Sus scrofa (pig) | IC50 | 2.5000 | 1 | 1 |
| minalrestat | Sus scrofa (pig) | IC50 | 0.0400 | 1 | 1 |
| sorbinil | Sus scrofa (pig) | IC50 | 2.9500 | 2 | 2 |
| epalrestat | Sus scrofa (pig) | IC50 | 1.5000 | 1 | 1 |
| quercetin | Sus scrofa (pig) | IC50 | 38.4000 | 1 | 1 |
| valproate sodium | Sus scrofa (pig) | IC50 | 89.0000 | 1 | 1 |
| ethyl 1-benzyl-3-hydroxy-2(5h)-oxopyrrole-4-carboxylate | Sus scrofa (pig) | IC50 | 1.8252 | 2 | 2 |