Page last updated: 2024-08-07 19:54:24
Neuraminidase
[no definition available]
Synonyms
Research
Bioassay Publications (3)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (3)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| zanamivir | Influenza A virus (A/duck/Laos/25/2006(H5N1)) | IC50 | 0.0027 | 3 | 3 |
| zanamivir | Influenza A virus (A/duck/Laos/25/2006(H5N1)) | Ki | 0.0005 | 1 | 1 |
| oseltamivir | Influenza A virus (A/duck/Laos/25/2006(H5N1)) | IC50 | 2.0317 | 3 | 3 |
| oseltamivir | Influenza A virus (A/duck/Laos/25/2006(H5N1)) | Ki | 0.0011 | 1 | 1 |
| gs 4071 | Influenza A virus (A/duck/Laos/25/2006(H5N1)) | IC50 | 1.6300 | 1 | 1 |
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.Journal of medicinal chemistry, , Jul-26, Volume: 61, Issue:14, 2018
Susceptibility of highly pathogenic H5N1 influenza viruses to the neuraminidase inhibitor oseltamivir differs in vitro and in a mouse model.Antimicrobial agents and chemotherapy, , Volume: 53, Issue:7, 2009