Page last updated: 2024-08-07 16:54:56
Small conductance calcium-activated potassium channel protein 3
A small conductance calcium-activated potassium channel protein 3 that is encoded in the genome of rat. [OMA:P70605, PRO:DNx]
Synonyms
SK3;
SKCa 3;
SKCa3;
KCa2.3
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (15)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| tacrine | Rattus norvegicus (Norway rat) | IC50 | 0.0420 | 1 | 1 |
| vanoxerine | Rattus norvegicus (Norway rat) | IC50 | 0.0730 | 1 | 1 |
| gbr 12935 | Rattus norvegicus (Norway rat) | IC50 | 0.2980 | 1 | 1 |
| galantamine | Rattus norvegicus (Norway rat) | IC50 | 12.7000 | 1 | 1 |
| dequalinium chloride | Rattus norvegicus (Norway rat) | IC50 | 0.8800 | 3 | 3 |
| dequalinium chloride | Rattus norvegicus (Norway rat) | Ki | 0.1805 | 2 | 2 |
| pancuronium bromide | Rattus norvegicus (Norway rat) | IC50 | 6.8000 | 1 | 1 |
| atracurium | Rattus norvegicus (Norway rat) | Ki | 5.9000 | 1 | 1 |
| 1-ethyl-2-benzimidazolinone | Rattus norvegicus (Norway rat) | Ki | 50.0000 | 1 | 1 |
| ucl 1684 | Rattus norvegicus (Norway rat) | IC50 | 0.0030 | 1 | 1 |
| ucl 1684 | Rattus norvegicus (Norway rat) | Ki | 0.0018 | 1 | 1 |
| rs 102221 | Rattus norvegicus (Norway rat) | IC50 | 0.0015 | 1 | 1 |
| hymecromone | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| 7-hydroxycoumarin | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| bicuculline methochloride | Rattus norvegicus (Norway rat) | IC50 | 7.0000 | 1 | 1 |
| bicuculline methochloride | Rattus norvegicus (Norway rat) | Ki | 4.4000 | 1 | 1 |
| (r)-n-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine | Rattus norvegicus (Norway rat) | Ki | 50.0000 | 1 | 1 |
| ns 309 | Rattus norvegicus (Norway rat) | Ki | 50.0000 | 1 | 1 |
Drugs with Activation Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| dequalinium chloride | Rattus norvegicus (Norway rat) | Kd | 0.1800 | 1 | 1 |
| atracurium | Rattus norvegicus (Norway rat) | Kd | 6.4000 | 1 | 1 |
| ucl 1684 | Rattus norvegicus (Norway rat) | Kd | 0.0027 | 1 | 1 |
| (r)-n-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamine | Rattus norvegicus (Norway rat) | Kd | 0.0770 | 1 | 1 |