Page last updated: 2024-08-07 16:54:56

Small conductance calcium-activated potassium channel protein 3

A small conductance calcium-activated potassium channel protein 3 that is encoded in the genome of rat. [OMA:P70605, PRO:DNx]

Synonyms

SK3;
SKCa 3;
SKCa3;
KCa2.3

Research

Bioassay Publications (8)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Compounds (15)

Drugs with Inhibition Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
tacrineRattus norvegicus (Norway rat)IC500.042011
vanoxerineRattus norvegicus (Norway rat)IC500.073011
gbr 12935Rattus norvegicus (Norway rat)IC500.298011
galantamineRattus norvegicus (Norway rat)IC5012.700011
dequalinium chlorideRattus norvegicus (Norway rat)IC500.880033
dequalinium chlorideRattus norvegicus (Norway rat)Ki0.180522
pancuronium bromideRattus norvegicus (Norway rat)IC506.800011
atracuriumRattus norvegicus (Norway rat)Ki5.900011
1-ethyl-2-benzimidazolinoneRattus norvegicus (Norway rat)Ki50.000011
ucl 1684Rattus norvegicus (Norway rat)IC500.003011
ucl 1684Rattus norvegicus (Norway rat)Ki0.001811
rs 102221Rattus norvegicus (Norway rat)IC500.001511
hymecromoneRattus norvegicus (Norway rat)IC50500.000011
7-hydroxycoumarinRattus norvegicus (Norway rat)IC50500.000011
bicuculline methochlorideRattus norvegicus (Norway rat)IC507.000011
bicuculline methochlorideRattus norvegicus (Norway rat)Ki4.400011
(r)-n-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamineRattus norvegicus (Norway rat)Ki50.000011
ns 309Rattus norvegicus (Norway rat)Ki50.000011

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
dequalinium chlorideRattus norvegicus (Norway rat)Kd0.180011
atracuriumRattus norvegicus (Norway rat)Kd6.400011
ucl 1684Rattus norvegicus (Norway rat)Kd0.002711
(r)-n-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphthylamineRattus norvegicus (Norway rat)Kd0.077011