Compounds > 2,4,6-trimethylaniline
Page last updated: 2024-11-05

2,4,6-trimethylaniline

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,4,6-Trimethylaniline, also known as mesidine, is a colorless liquid aromatic amine. It is an important precursor in the synthesis of various organic compounds, including dyes, pharmaceuticals, and pesticides. 2,4,6-Trimethylaniline is synthesized through the reduction of 2,4,6-trinitroanisole using a reducing agent like iron and hydrochloric acid. The compound is known for its ability to act as a weak base and can be used in the formation of salts with strong acids. Research on 2,4,6-trimethylaniline focuses on its potential applications in materials science, especially in the development of conductive polymers and organic semiconductors. Its unique electronic and structural properties make it a valuable component for developing new materials with advanced electrical conductivity and optical properties. The compound is also studied for its potential in catalysis and as a building block in the synthesis of complex organic molecules.'

2,4,6-trimethylaniline: RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6913
CHEBI ID82545
SCHEMBL ID139002
MeSH IDM0061715

Synonyms (55)

Synonym
BIDD:GT0806
88-05-1
2,4,6-trimethyl aniline
mesitylamine
einecs 201-794-3
mesidine
2-amino-1,3,5-trimethylbenzene
mesidin [czech]
mesidin
aminomesitylene
2-aminomesitylene
mesitylene, 2-amino-
1-amino-2,4,6-trimethylbenzen [czech]
2,4,6-trimethylbenzenamine
ccris 2871
hsdb 2694
aniline, 2,4,6-trimethyl-
nsc-31
2,4,6-trimethylaniline
inchi=1/c9h13n/c1-6-4-7(2)9(10)8(3)5-6/h4-5h,10h2,1-3h
benzenamine, 2,4,6-trimethyl-
2,4,6-trimethylaniline, 98%
AKOS000119132
C19540
(2,4,6-trimethyl-phenyl)-amine
STL164356
2,4,6-trimethylphenylamine
1-amino-2,4,6-trimethylbenzen
unii-yir5crl5bg
yir5crl5bg ,
FT-0609896
2,4,6-trimethylaniline [iarc]
1-amino-2,4,6-trimethylbenzene
2-amino-1,3,5-trimethylbenzene [hsdb]
SCHEMBL139002
CHEBI:82545
DTXSID5043847
mesityl amine
2,4,6-trimethyl-aniline
2,4,6-trimethyl-phenylamine
benzeneamine, 2,4,6-trimethyl-
W-100422
STR00896
CS-W007785
F2190-0482
2,4,6-trimethylaniline (mesidine), nd25=1,4959
2,4,6-trimethylaniline, purum, >=98.0% (gc)
mfcd00007740
Q4596776
AMY25805
CCG-302506
D77687
2-nitrophenyln-acetyl-alpha-dgalactosaminide
EN300-19092
Z104472738
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
substituted aniline
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 36.98

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index36.98 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.16 (4.65)
Search Engine Demand Index50.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (36.98)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
carbamates
[no description available]		1.9910amino-acid anion
guaiacol
Guaiacol: An agent thought to have disinfectant properties and used as an expectorant. (From Martindale, The Extra Pharmacopoeia, 30th ed, p747). methylcatechol : Any member of the class of catechols carrying one or more methyl substituents.. guaiacol : A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.		1.9610guaiacolsdisinfectant;
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor;
expectorant;
plant metabolite
nitrates
Nitrates: Inorganic or organic salts and esters of nitric acid. These compounds contain the NO3- radical.		2.0510monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
phenol
[no description available]		1.9610phenolsantiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite
2,4-xylidine
2,4-xylidine: RN given refers to parent cpd; structure. 2,4-dimethylaniline : A primary arylamine that is aniline in which the hydrogens at the 2- and 4-positions are replaced by methyl groups. A clear to yellow liquid, it is used in production of certain dyes, pesticides and other chemicals.		2.420dimethylaniline;
primary arylamine
dianisidine
Dianisidine: Highly toxic compound which can cause skin irritation and sensitization. It is used in manufacture of azo dyes.		1.9610biphenyls
2,4,5-trimethylaniline
2,4,5-trimethylaniline: RN given refers to parent cpd		1.9610substituted aniline
2,6-dichloroindophenol
2,6-Dichloroindophenol: A dye used as a reagent in the determination of vitamin C.. 2,6-dichloroindophenol : A quinone imine that is indophenol substituted by chloro groups at positions 2 and 6.. N-3,5-dichloro-4-hydroxyphenyl-1,4-benzoquinone imine : 1,4-benzoquinone imine having a 3,5-dichloro-4-hydroxyphenyl substituent attached to the nitrogen atom.		1.9610dichlorobenzene;
quinone imine
sodium dodecyl sulfate
Sodium Dodecyl Sulfate: An anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.. sodium dodecyl sulfate : An organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate.		1.9910organic sodium saltdetergent;
protein denaturant
ConditionIndicatedRelationship StrengthStudiesTrials
Experimental Neoplasms
[description not available]		02.3620
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		0210
Carcinoma, Anaplastic
[description not available]		01.9510
Cancer of Pituitary
[description not available]		01.9510
Carcinoma
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.		01.9510
Pituitary Neoplasms
Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.		01.9510