Compounds > 8,5'-cyclo-2'-deoxyadenosine
Page last updated: 2024-07-31 18:48:11

8,5'-cyclo-2'-deoxyadenosine

Description

8,5'-cyclo-2'-deoxyadenosine : An organic heterotetracyclic compound obtained by intramolecular formation of a C-C bond between positions 8 and 5' of 2'-deoxyadenosine. [CHeBI]

Cross-References

ID SourceID
PubMed CID11172711
SCHEMBL ID22982665
CHEBI ID131825
MeSH IDM0159115

Synonyms (9)

Synonym
(6r,7s,8s,10r)-4-amino-7,8,9,10-tetrahydro-6h-7,10-epoxyazepino[1,2-e]purine-6,8-diol
cycloda
cyclo-da
CHEBI:131825
8,5'-cyclo-2'-deoxyadenosine
(5'r)-5',8-cyclo-2'-deoxyadenosine
Q27225266
SCHEMBL22982665
(1r,11r,12s,13s)-7-amino-15-oxa-2,4,6,9-tetrazatetracyclo[10.2.1.02,10.03,8]pentadeca-3,5,7,9-tetraene-11,13-diol

Roles (1)

RoleDescription
Mycoplasma genitalium metaboliteAny bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.

Drug Classes (5)

ClassDescription
organic heterotetracyclic compound
bridged compoundA polycyclic compound in which two rings have two or more atoms in common.
N-glycosyl compoundA glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond.
diolA compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols.
aromatic amineAn amino compound in which the amino group is linked directly to an aromatic system.

Research

Studies (50)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (2.00)18.7374
1990's2 (4.00)18.2507
2000's16 (32.00)29.6817
2010's27 (54.00)24.3611
2020's4 (8.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews3 (5.88%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other48 (94.12%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
aristolochic acid i
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
racemethorphan
0
aromatic ether;
morphinane alkaloid;
morphinane-like compound;
organic heterotetracyclic compound		00low000000
ellipticine
0
indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
polycyclic heteroarene		antineoplastic agent;
plant metabolite		00low000000
lysergic acid diethylamide
0
ergoline alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound		dopamine agonist;
hallucinogen;
serotonergic agonist		00low000000
vincristine
0
acetate ester;
formamides;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent;
drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator		00low000000
gliotoxin
0
dipeptide;
organic disulfide;
organic heterotetracyclic compound;
pyrazinoindole		antifungal agent;
EC 2.5.1.58 (protein farnesyltransferase) inhibitor;
immunosuppressive agent;
mycotoxin;
proteasome inhibitor		00low000000
galantamine
0
benzazepine alkaloid fundamental parent;
benzazepine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound		antidote to curare poisoning;
cholinergic drug;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
plant metabolite		00low000000
beta-erythroidine
0
delta-lactone;
indole alkaloid;
organic heterotetracyclic compound;
tertiary amino compound		muscle relaxant;
plant metabolite		00low000000
hematoxylin
0
organic heterotetracyclic compound;
oxacycle;
polyphenol;
tertiary alcohol		histological dye;
plant metabolite		00low000000
podophyllotoxin
0
furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antimitotic;
antineoplastic agent;
keratolytic drug;
microtubule-destabilising agent;
plant metabolite;
tubulin modulator		00low000000
quinacridone
0
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		00low000000
glaucine
0
aporphine alkaloid;
organic heterotetracyclic compound;
polyether;
tertiary amino compound		antibacterial agent;
antineoplastic agent;
antitussive;
muscle relaxant;
NF-kappaB inhibitor;
plant metabolite;
platelet aggregation inhibitor;
rat metabolite		00low000000
palmatine
0
berberine alkaloid;
organic heterotetracyclic compound		plant metabolite00low000000
dihydro-beta-erythroidine
0
delta-lactone;
organic heterotetracyclic compound;
tertiary amino compound		nicotinic antagonist00low000000
nicergoline
0
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		00low000000
etoposide
0
beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor		00low000000
vindesine
0
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
primary carboxamide;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent00low000000
pergolide
0
diamine;
methyl sulfide;
organic heterotetracyclic compound		antiparkinson drug;
dopamine agonist		00low000000
calanolide a
0
cyclic ether;
delta-lactone;
organic heterotetracyclic compound;
secondary alcohol		HIV-1 reverse transcriptase inhibitor;
plant metabolite		00low000000
nile red
0
aromatic amine;
cyclic ketone;
organic heterotetracyclic compound;
tertiary amino compound		fluorochrome;
histological dye		00low000000
tetrahydropalmatine
0
an (S)-7,8,13,14-tetrahydroprotoberberine;
berberine alkaloid;
organic heterotetracyclic compound		adrenergic agent;
dopaminergic antagonist;
non-narcotic analgesic		00low000000
columbamine
0
berberine alkaloid;
organic heterotetracyclic compound		00low000000
picropodophyllin
0
furonaphthodioxole;
lignan;
organic heterotetracyclic compound		antineoplastic agent;
insulin-like growth factor receptor 1 antagonist;
plant metabolite;
tyrosine kinase inhibitor		00low000000
brazilin
0
catechols;
organic heterotetracyclic compound;
tertiary alcohol		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
antioxidant;
apoptosis inducer;
biological pigment;
hepatoprotective agent;
histological dye;
NF-kappaB inhibitor;
plant metabolite		00low000000
tryptanthrine
0
alkaloid antibiotic;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		00low000000
cryptolepine
0
indole alkaloid;
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		anti-inflammatory agent;
antimalarial;
antineoplastic agent;
cysteine protease inhibitor;
plant metabolite		00low000000
9-hydroxyellipticine
0
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		antineoplastic agent00low000000
beta-peltatin
0
furonaphthodioxole;
gamma-lactone;
lignan;
organic heterotetracyclic compound;
phenols		antineoplastic agent;
plant metabolite		00low000000
alpha-peltatin
0
furonaphthodioxole;
gamma-lactone;
lignan;
organic heterotetracyclic compound;
phenols		antineoplastic agent;
metabolite		00low000000
canthin-6-one
0
enone;
indole alkaloid;
organic heterotetracyclic compound		antimycobacterial drug;
metabolite		00low000000
allocryptopine
0
aromatic ether;
cyclic acetal;
cyclic ketone;
dibenzazecine alkaloid;
organic heterotetracyclic compound;
tertiary amino compound		00low000000
berbine
0
berberine alkaloid;
isoquinoline alkaloid fundamental parent;
organic heterotetracyclic compound		00low000000
aristolochic acid ii
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
megestrol acetate
0
bridged compound;
organic heterotetracyclic compound;
secondary alcohol;
sesquiterpene lactone;
spiro compound;
tertiary alcohol;
tetrol		GABA antagonist;
neurotoxin;
phytogenic insecticide;
plant metabolite		00low000000
4'-demethylpodophyllotoxin
0
furonaphthodioxole;
organic heterotetracyclic compound;
phenols		metabolite00low000000
4'-demethylepipodophyllotoxin
0
furonaphthodioxole;
organic heterotetracyclic compound;
phenols		antineoplastic agent00low000000
psorospermin
0
epoxide;
organic heterotetracyclic compound;
xanthones		antineoplastic agent;
plant metabolite		00low000000
asperlicin c
0
asperlicins;
indoles;
organic heterotetracyclic compound		Aspergillus metabolite;
cholecystokinin antagonist		00low000000
schizandrin b
0
aromatic ether;
cyclic acetal;
organic heterotetracyclic compound;
oxacycle;
tannin		anti-asthmatic agent;
anti-inflammatory agent;
antilipemic drug;
antioxidant;
apoptosis inhibitor;
hepatoprotective agent;
nephroprotective agent;
neuroprotective agent;
plant metabolite		00low000000
corytuberine
0
aporphine alkaloid;
aromatic ether;
organic heterotetracyclic compound;
polyphenol;
tertiary amino compound		plant metabolite00low000000
5,6-didehydrosparteine
0
organic heterotetracyclic compound;
quinolizidine alkaloid;
tertiary amino compound		human xenobiotic metabolite00low000000
aristolochic acid D
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
nephrotoxin;
toxin		00low000000
stephenanthrine
0
cyclic acetal;
organic heterotetracyclic compound;
tertiary amino compound		00low000000
aristolochic acid c
0
aristolochic acids;
aromatic ether;
C-nitro compound;
cyclic acetal;
monocarboxylic acid;
organic heterotetracyclic compound		carcinogenic agent;
metabolite;
mutagen;
nephrotoxin;
toxin		00low000000
erysodine
0
aromatic ether;
diether;
Erythrina alkaloid;
organic heterotetracyclic compound;
phenols		antiparasitic agent;
nicotinic antagonist;
phytogenic insecticide		00low000000
top 53
0
furonaphthodioxole;
gamma-lactone;
organic heterotetracyclic compound;
phenols;
tertiary amino compound		antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor		00low000000
pronuciferine
0
aromatic ether;
cyclic ketone;
isoquinoline alkaloid;
isoquinolines;
organic heterotetracyclic compound		plant metabolite00low000000
vincaleukoblastine
0
acetate ester;
indole alkaloid fundamental parent;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
tertiary alcohol;
tertiary amino compound;
vinca alkaloid		antineoplastic agent;
immunosuppressive agent;
microtubule-destabilising agent;
plant metabolite		00low000000
5-methoxycanthin-6-one
0
alkaloid;
organic heterotetracyclic compound		00low000000
pd 146176
0
organic heterotetracyclic compound;
organonitrogen heterocyclic compound;
organosulfur heterocyclic compound		antiatherogenic agent;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
ferroptosis inhibitor		00low000000
Amalorin
0
alkaloid;
organic heterotetracyclic compound		00low000000
sampangine
0
alkaloid;
organic heterotetracyclic compound		antifungal agent;
plant metabolite		00low000000
discretamine
0
berberine alkaloid;
organic heterotetracyclic compound		EC 5.99.1.2 (DNA topoisomerase) inhibitor;
plant metabolite		00low000000
tetrahydrocolumbamine
0
berberine alkaloid;
organic heterotetracyclic compound		00low000000
ergonovine
0
ergot alkaloid;
monocarboxylic acid amide;
organic heterotetracyclic compound;
primary alcohol;
secondary amino compound;
tertiary amino compound		diagnostic agent;
fungal metabolite;
oxytocic;
toxin		00low000000
costatolide
0
cyclic ether;
delta-lactone;
organic heterotetracyclic compound;
secondary alcohol		HIV-1 reverse transcriptase inhibitor;
plant metabolite		00low000000
piperlactam s
0
alkaloid;
aromatic ether;
gamma-lactam;
organic heterotetracyclic compound;
phenols		anti-inflammatory agent;
antioxidant;
plant metabolite		00low000000
6-methyl-12-indolo[1,2-c]quinazolinamine
0
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		00low000000
sb-224289
0
1,2,4-oxadiazole;
azaspiro compound;
benzamides;
organic heterotetracyclic compound		serotonergic antagonist00low000000
alsterpaullone
0
C-nitro compound;
caprolactams;
organic heterotetracyclic compound		anti-HIV-1 agent;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor		00low000000
bryostatin 1
0
acetate ester;
bryostatins;
cyclic hemiketal;
enoate ester;
methyl ester;
organic heterotetracyclic compound;
secondary alcohol		alpha-secretase activator;
anti-HIV-1 agent;
antineoplastic agent;
marine metabolite;
protein kinase C agonist		00low000000
azadirachtin
0
acetate ester;
azadirachtin;
cyclic hemiketal;
enoate ester;
epoxide;
methyl ester;
organic heterotetracyclic compound;
secondary alcohol;
tertiary alcohol		hepatoprotective agent00low000000
geissospermine
0
indole alkaloid;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound		EC 3.1.1.7 (acetylcholinesterase) inhibitor00low000000
maytansine
0
alpha-amino acid ester;
carbamate ester;
epoxide;
maytansinoid;
organic heterotetracyclic compound;
organochlorine compound		antimicrobial agent;
antimitotic;
antineoplastic agent;
plant metabolite;
tubulin modulator		00low000000
ellagic acid
0
catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent		00low000000
t-2 toxin
0
acetate ester;
organic heterotetracyclic compound;
trichothecene		apoptosis inducer;
cardiotoxic agent;
DNA synthesis inhibitor;
environmental contaminant;
fungal metabolite;
mycotoxin;
neurotoxin		00low000000
vinorelbine
0
acetate ester;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
ring assembly;
vinca alkaloid		antineoplastic agent;
photosensitizing agent		00low000000
rifamycin b
0
acetate ester;
carboxylic acid;
organic heterotetracyclic compound;
rifamycins		00low000000
2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz(h)imidazo(4,5-f)isoquinoline-7-one
0
organic heterotetracyclic compound;
organofluorine compound		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor00low000000
arglabin
0
epoxide;
gamma-lactone;
organic heterotetracyclic compound;
sesquiterpene lactone		antineoplastic agent;
metabolite		00low000000
rifamycin sv
0
acetate ester;
cyclic ketal;
lactam;
macrocycle;
organic heterotetracyclic compound;
polyphenol;
rifamycins		antimicrobial agent;
antitubercular agent;
bacterial metabolite		00low000000
muconomycin a
0
epoxide;
macrolide antibiotic;
macrotriolide;
organic heterotetracyclic compound;
trichothecene		00low000000
bryostatin 2
0
bryostatins;
cyclic hemiketal;
enoate ester;
methyl ester;
organic heterotetracyclic compound;
secondary alcohol		antineoplastic agent;
marine metabolite;
protein kinase C agonist		00low000000
1-azakenpaullone
0
lactam;
organic heterotetracyclic compound;
organobromine compound;
organonitrogen heterocyclic compound		EC 2.7.11.26 (tau-protein kinase) inhibitor;
Wnt signalling activator		00low000000
ergoline
0
diamine;
ergoline alkaloid;
indole alkaloid fundamental parent;
indole alkaloid;
organic heterotetracyclic compound		00low000000
lergotrile
0
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		00low000000
px-866
0
acetate ester;
delta-lactone;
organic heterotetracyclic compound;
tertiary amino compound		EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor00low000000
xenovulene a
0
cyclic ether;
enone;
organic heterotetracyclic compound;
sesquiterpenoid		GABA antagonist;
metabolite		00low000000
9-methoxycanthin-6-one
0
aromatic ether;
indole alkaloid;
organic heterotetracyclic compound		antineoplastic agent;
antiplasmodial drug;
metabolite		00low000000
HT-2 toxin
0
acetate ester;
organic heterotetracyclic compound;
trichothecene		apoptosis inducer;
fungal metabolite		00low000000
arisugacin
0
aromatic ether;
delta-lactone;
enone;
organic heterotetracyclic compound;
tertiary alcohol		antimicrobial agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite;
Penicillium metabolite		00low000000
vinflunine
0
acetate ester;
methyl ester;
organic heteropentacyclic compound;
organic heterotetracyclic compound;
semisynthetic derivative;
vinca alkaloid		antineoplastic agent00low000000
ossamycin
0
cyclic hemiketal;
macrolide antibiotic;
organic heterotetracyclic compound;
secondary alcohol;
spiroketal;
tertiary alcohol		antineoplastic agent;
bacterial metabolite		00low000000
liphagal
0
aldehyde;
cyclic ether;
meroterpenoid;
organic heterotetracyclic compound;
polyphenol		EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
metabolite		00low000000
drymaritin
0
enol ether;
enone;
indole alkaloid;
organic heterotetracyclic compound		anti-HIV agent;
metabolite		00low000000
pyripyropene a
0
organic heterotetracyclic compound;
sesquiterpenoid		acyl-CoA:cholesterol acyltransferase 2 inhibitor;
metabolite		00low000000
3-[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea
0
organic heterotetracyclic compound;
organonitrogen heterocyclic compound		00low000000
hapalindole u
0
hapalindole;
isocyanide;
organic heterotetracyclic compound		00low000000
chaetominine
0
indole alkaloid;
lactam;
organic heterotetracyclic compound;
quinazolines		metabolite00low000000
berkeleydione
0
beta-diketone;
cyclic terpene ketone;
meroterpenoid;
methyl ester;
organic heterotetracyclic compound;
terpene lactone;
tertiary alcohol;
tertiary alpha-hydroxy ketone		antineoplastic agent;
cysteine protease inhibitor;
Penicillium metabolite		00low000000
caribenol a
0
organic heterotetracyclic compound;
terpene lactone;
tertiary alcohol		antimalarial;
antitubercular agent;
metabolite		00low000000
cx 5461
0
diazepine;
naphthyridine derivative;
organic heterotetracyclic compound;
pyrazines;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
EC 2.7.7.6 (RNA polymerase) inhibitor		00low000000
lycojapodine a
0
alkaloid;
bridged compound;
cyclic ketone;
lactone;
organic heterotetracyclic compound		anti-HIV-1 agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
metabolite		00low000000
aspirochlorine
0
organic heterotetracyclic compoundAspergillus metabolite00low000000
alectinib
0
aromatic ketone;
morpholines;
nitrile;
organic heterotetracyclic compound;
piperidines		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
afidopyropen
0
cyclopropanecarboxylate ester;
organic heterotetracyclic compound;
pyridines;
secondary alcohol		agrochemical;
insecticide;
TRPV channel modulator		00low000000
stemmadenine
0
Aspidosperma alkaloid;
methyl ester;
monoterpenoid indole alkaloid;
organic heterotetracyclic compound;
primary alcohol		plant metabolite00low000000
mycocyclosin
0
2,5-diketopiperazines;
organic heterotetracyclic compound;
polyphenol		metabolite00low000000
mk-8742
0
carbamate ester;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organic heterotetracyclic compound;
ring assembly		antiviral drug;
hepatitis C virus nonstructural protein 5A inhibitor;
hepatoprotective agent		00low000000
pf-06463922
0
aminopyridine;
aromatic ether;
azamacrocycle;
benzamides;
cyclic ether;
monofluorobenzenes;
nitrile;
organic heterotetracyclic compound;
pyrazoles		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
atogepant
0
azaspiro compound;
organic heterotetracyclic compound;
piperidones;
secondary carboxamide;
trifluorobenzene		calcitonin gene-related peptide receptor antagonist00low000000
bictegravir
0
monocarboxylic acid amide;
organic heterotetracyclic compound;
secondary carboxamide;
trifluorobenzene		HIV-1 integrase inhibitor00low000000
8,5'-cyclo-2'-deoxyguanosine
0
aromatic amine;
bridged compound;
diol;
N-glycosyl compound;
organic heterotetracyclic compound		Mycoplasma genitalium metabolite00low000000
chlorendic acid
0
bridged compound;
dicarboxylic acid;
organochlorine compound		carcinogenic agent00low000000
triethylenediamine
0
bridged compound;
diamine;
saturated organic heterobicyclic parent;
tertiary amino compound		antioxidant;
catalyst;
reagent		00low000000
cytisine
0
alkaloid;
bridged compound;
lactam;
organic heterotricyclic compound;
secondary amino compound		nicotinic acetylcholine receptor agonist;
phytotoxin;
plant metabolite		00low000000
bicozamycin
0
azabicycloalkane;
bridged compound		antibacterial agent;
antidiarrhoeal drug;
antiinfective agent		00low000000
alpha-bergamotene
0
bridged compound;
polycyclic olefin;
sesquiterpene		plant metabolite;
volatile oil component		00low000000
tandospirone
0
bridged compound;
dicarboximide;
N-alkylpiperazine;
N-arylpiperazine;
pyrimidines		antidepressant;
anxiolytic drug		00low000000
ecteinascidin 743
0
acetate ester;
azaspiro compound;
bridged compound;
hemiaminal;
isoquinoline alkaloid;
lactone;
organic heteropolycyclic compound;
organic sulfide;
oxaspiro compound;
polyphenol;
tertiary amino compound		alkylating agent;
angiogenesis modulating agent;
anti-inflammatory agent;
antineoplastic agent;
marine metabolite		00low000000
lurasidone
0
1,2-benzisothiazole;
bridged compound;
dicarboximide;
N-arylpiperazine		adrenergic antagonist;
dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist		00low000000
stevioside
0
beta-D-glucoside;
bridged compound;
diterpene glycoside;
ent-kaurane diterpenoid;
tetracyclic diterpenoid		anti-inflammatory agent;
antineoplastic agent;
antioxidant;
hypoglycemic agent;
plant metabolite;
sweetening agent		00low000000
steviol
0
bridged compound;
ent-kaurane diterpenoid;
monocarboxylic acid;
tertiary allylic alcohol;
tetracyclic diterpenoid		antineoplastic agent00low000000
16beta,17-dihydroxy-ent-kaurane-19-oic acid
0
bridged compound;
diol;
ent-kaurane diterpenoid;
hydroxy monocarboxylic acid;
primary alcohol;
tertiary alcohol		anti-HIV agent;
metabolite		00low000000
sordaricin
0
3-oxo monocarboxylic acid;
aldehyde;
bridged compound;
primary alcohol;
tetracyclic diterpenoid		antifungal agent;
fungal metabolite		00low000000
komaroviquinone
0
bridged compound;
lactol;
p-quinones;
tetracyclic diterpenoid		metabolite;
trypanocidal drug		00low000000
bicyclo(2.2.1)heptene
0
bridged compound;
carbobicyclic compound;
cyclic olefin		00low000000
iwr-1 exo
0
bridged compound;
dicarboximide		axin stabilizer00low000000
sf 2370
0
bridged compound;
gamma-lactam;
methyl ester;
organic heterooctacyclic compound		antimicrobial agent;
bacterial metabolite;
EC 2.7.11.13 (protein kinase C) inhibitor;
tropomyosin-related kinase B receptor antagonist		00low000000
sr 144528
0
bridged compound;
monochlorobenzenes;
pyrazoles;
secondary carboxamide		CB2 receptor antagonist;
EC 2.3.1.26 (sterol O-acyltransferase) inhibitor		00low000000
catharanthine
0
alkaloid ester;
bridged compound;
methyl ester;
monoterpenoid indole alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		00low000000
cedrene
0
bridged compound;
carbotricyclic compound;
polycyclic olefin;
sesquiterpene		human urinary metabolite;
volatile oil component		00low000000
yunaconitine
0
acetate ester;
aromatic ether;
benzoate ester;
bridged compound;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary alcohol;
tertiary amino compound		antifeedant;
human urinary metabolite;
phytotoxin;
plant metabolite;
xenobiotic		00low000000
ly 404039
0
bridged compound;
dicarboxylic acid;
non-proteinogenic amino acid derivative;
organic heterobicyclic compound;
sulfone		antipsychotic agent;
anxiolytic drug;
dopamine agonist;
metabotropic glutamate receptor agonist		00low000000
ly 379268
0
amino dicarboxylic acid;
bridged compound;
organic heterobicyclic compound		antipsychotic agent;
anxiolytic drug;
metabotropic glutamate receptor agonist;
neuroprotective agent		00low000000
hu 308
0
aromatic ether;
bridged compound;
carbobicyclic compound;
primary allylic alcohol;
synthetic cannabinoid		anti-inflammatory agent;
antihypertensive agent;
apoptosis inhibitor;
bone density conservation agent;
CB2 receptor agonist		00low000000
sativene
0
bridged compound;
sesquiterpene		00low000000
benzoylaconine
0
benzoate ester;
bridged compound;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary alcohol;
tertiary amino compound;
tetrol		phytotoxin;
plant metabolite		00low000000
dihydroagarofuran
0
bridged compound;
cyclic ether;
eudesmane sesquiterpenoid;
organic heterotricyclic compound		metabolite00low000000
deoxyaconitine
0
acetate ester;
benzoate ester;
bridged compound;
diol;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary amino compound		plant metabolite00low000000
oxypaeoniflora
0
4-hydroxybenzoate ester;
beta-D-glucoside;
bridged compound;
cyclic acetal;
lactol;
monoterpene glycoside		plant metabolite00low000000
rubusoside
0
beta-D-glucoside;
bridged compound;
steviol glycoside;
tetracyclic diterpenoid		plant metabolite;
sweetening agent		00low000000
aspergillide b
0
bridged compound;
cyclic ether;
macrolide;
secondary alcohol		antineoplastic agent;
Aspergillus metabolite		00low000000
benzoylmesaconine
0
benzoate ester;
bridged compound;
diterpene alkaloid;
organic heteropolycyclic compound;
polyether;
secondary alcohol;
tertiary alcohol;
tertiary amino compound;
tetrol		analgesic;
antiinfective agent;
plant metabolite		00low000000
albiflorin
0
benzoate ester;
beta-D-glucoside;
bridged compound;
gamma-lactone;
monoterpene glycoside;
secondary alcohol		neuroprotective agent;
plant metabolite		00low000000
salvileucalin b
0
bridged compound;
diterpenoid;
furans;
gamma-lactone		antineoplastic agent;
metabolite		00low000000
iwr-1 endo
0
benzamides;
bridged compound;
dicarboximide;
quinolines		axin stabilizer;
Wnt signalling inhibitor		00low000000
N-[9-(dichloromethylene)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxamide
0
aromatic amide;
bridged compound;
olefinic compound;
organochlorine compound;
organofluorine compound;
pyrazoles		00low000000
streptolydigin
0
bridged compound;
cyclic ketal;
enol;
monocarboxylic acid amide;
N-glycosyl compound;
organic heterobicyclic compound;
pyrrolidinone;
spiro-epoxide		antimicrobial agent;
bacterial metabolite;
EC 2.7.7.6 (RNA polymerase) inhibitor		00low000000
ledipasvir
0
azaspiro compound;
benzimidazole;
bridged compound;
carbamate ester;
carboxamide;
fluorenes;
imidazoles;
L-valine derivative;
N-acylpyrrolidine;
organofluorine compound		antiviral drug;
hepatitis C protease inhibitor		00low000000
aspergillide a
0
bridged compound;
cyclic ether;
macrolide;
secondary alcohol		antineoplastic agent;
Aspergillus metabolite		00low000000
capilliposide b
0
alpha-L-arabinopyranoside;
bridged compound;
cyclic ether;
diol;
hexacyclic triterpenoid;
hexanoate ester;
lactol;
secondary alcohol;
tetrasaccharide derivative;
triterpenoid saponin		antineoplastic agent;
plant metabolite		00low000000
paeoniflorigenone
0
alicyclic ketone;
benzoate ester;
bridged compound;
cyclic acetal;
lactol;
monoterpenoid		neuromuscular agent;
plant metabolite		00low000000
arabinofuranosyluracil
0
N-glycosyl compoundmetabolite00low000000
thymine arabinoside
0
N-glycosyl compound00low000000
rebeccamycin
0
indolocarbazole;
N-glycosyl compound;
organic heterohexacyclic compound;
organochlorine compound		00low000000
8-azaadenosine
0
N-glycosyl compound00low000000
clitocine
0
N-glycosyl compound00low000000
nsc 154020
0
N-glycosyl compound00low000000
4'-azidocytidine
0
N-glycosyl compound00low000000
5'-deoxy-5-fluorocytidine
0
N-glycosyl compound00low000000
imidazoleacetic acid ribotide
0
imidazoles;
monocarboxylic acid;
N-glycosyl compound;
ribose monophosphate		00low000000
3-deazauridine
0
N-glycosyl compound00low000000
epz004777
0
N-glycosyl compound00low000000
2,2'-thiodiethanol
0
aliphatic sulfide;
diol		antineoplastic agent;
antioxidant;
metabolite;
solvent		00low000000
chloramphenicol
0
C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor		00low000000
triethylene glycol
0
diol;
poly(ethylene glycol);
primary alcohol		plasticiser00low000000
1-butyrylglycerol
0
1-monoglyceride;
butyrate ester;
diol;
fatty acid ester		00low000000
hexamethylene glycol
0
diol;
primary alcohol		00low000000
1,2-cyclohexanediol
0
diol00low000000
ancitabine
0
diol;
organic heterotricyclic compound		antimetabolite;
antineoplastic agent;
prodrug		00low000000
pyoluteorin
0
aromatic ketone;
beta-hydroxy ketone;
diol;
organochlorine compound;
organochlorine pesticide;
polyketide;
pyrroles;
resorcinols		antibacterial agent;
antifungal agent;
apoptosis inducer;
bacterial metabolite;
marine metabolite		00low000000
diisopropanolnitrosamine
0
diol;
nitrosamine;
secondary alcohol		carcinogenic agent00low000000
16-hydroxytestosterone
0
16alpha-hydroxy steroid;
17beta-hydroxy steroid;
3-oxo-Delta(4) steroid;
androstanoid;
C19-steroid;
diol;
secondary alcohol		androgen00low000000
nebivolol
0
chromanes;
diol;
organofluorine compound;
secondary alcohol;
secondary amino compound		00low000000
oxetanocin a
0
diol;
nucleoside analogue;
oxetanes;
primary alcohol		anti-HIV agent;
antibacterial agent;
bacterial metabolite		00low000000
nucleocidin
0
6-aminopurines;
adenosines;
diol;
organofluorine compound;
sulfamate ester		antibacterial agent;
bacterial metabolite;
nucleoside antibiotic;
protein synthesis inhibitor;
trypanocidal drug		00low000000
betulin
0
diol;
pentacyclic triterpenoid		analgesic;
anti-inflammatory agent;
antineoplastic agent;
antiviral agent;
metabolite		00low000000
2,5-bis(hydroxymethyl)furan
0
diol;
furans		00low000000
2,8-dihydroxyadenine
0
6-aminopurines;
diol;
heteroaryl hydroxy compound;
oxopurine		human urinary metabolite;
mammalian metabolite;
mouse metabolite;
nephrotoxic agent		00low000000
erythrodiol
0
diol;
pentacyclic triterpenoid;
primary alcohol;
secondary alcohol		plant metabolite00low000000
fumitremorgin a
0
aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide		mycotoxin00low000000
hawkinsin
0
cycloalkene;
cysteine derivative;
dicarboxylic acid;
diol;
secondary allylic alcohol;
tertiary allylic alcohol		biomarker;
human urinary metabolite		00low000000
veratrylglycerol-beta-guaiacyl ether
0
dimethoxybenzene;
diol		00low000000
xv 638
0
1,3-thiazoles;
benzamides;
diazepanone;
diol;
secondary alcohol;
secondary carboxamide;
ureas		HIV protease inhibitor00low000000
picrotin
0
diol;
epoxide;
gamma-lactone;
organic heteropentacyclic compound;
picrotoxane sesquiterpenoid;
tertiary alcohol		plant metabolite00low000000
colforsin daropate
0
acetate ester;
carboxylic ester;
cyclic ketone;
diol;
organic heterotricyclic compound;
tertiary amino compound		adenylate cyclase agonist;
antihypertensive agent;
cardiotonic drug;
vasodilator agent		00low000000
fumonisin b2
0
diester;
diol;
fumonisin;
primary amino compound		Aspergillus metabolite;
carcinogenic agent		00low000000
14,15-dihydroxyeicosatrienoic acid
0
DHET;
diol;
secondary allylic alcohol		mouse metabolite00low000000
8-isoprostaglandin e2
0
cyclic ketone;
diol;
prostanoid;
secondary alcohol		bronchoconstrictor agent;
human metabolite;
rat metabolite;
vasoconstrictor agent		00low000000
calcifediol
0
D3 vitamins;
diol;
hydroxycalciol		bone density conservation agent;
human metabolite;
metabolite;
mouse metabolite;
nutraceutical		00low000000
fortimicin a
0
amino cyclitol glycoside;
aminoglycoside antibiotic;
diol;
monocarboxylic acid amide;
primary amino compound		antibacterial agent;
metabolite		00low000000
8-hydroxygeraniol
0
diol;
monoterpenoid;
prenols		00low000000
pederin
0
cyclic ketal;
diol;
oxanes;
polyketide;
secondary alcohol;
secondary carboxamide		antimitotic;
antineoplastic agent;
bacterial metabolite;
vesicant		00low000000
ro 42-5892
0
cyclopropanes;
diol;
L-histidine derivative;
secondary carboxamide;
sulfone		antihypertensive agent;
EC 3.4.23.15 (renin) inhibitor;
peptidomimetic;
vasodilator agent		00low000000
riddelliine n-oxide
0
diol;
macrocyclic lactone;
olefinic compound;
organic heterotricyclic compound;
primary alcohol;
pyrrolizine alkaloid;
tertiary alcohol;
tertiary amine oxide		carcinogenic agent;
genotoxin;
human xenobiotic metabolite;
Jacobaea metabolite;
mutagen;
rat metabolite		00low000000
3-hydroxyretinol
0
diol;
retinoid		00low000000
hypothemycin
0
aromatic ether;
diol;
enone;
epoxide;
macrolide;
phenols;
polyketide;
secondary alpha-hydroxy ketone		antifungal agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
fungal metabolite		00low000000
protylonolide
0
diol;
enone;
macrolide		metabolite00low000000
alpha-onocerin
0
diol;
olefinic compound;
secondary alcohol;
triterpenoid		plant metabolite00low000000
neodysiherbaine a
0
amino dicarboxylic acid;
diol;
furopyran;
hydroxy carboxylic acid		animal metabolite;
excitatory amino acid agonist;
marine metabolite		00low000000
cortistatin a
0
cortistatins;
diol;
secondary alcohol		00low000000
verruculogen
0
aromatic ether;
diol;
indole alkaloid;
organic heterohexacyclic compound;
organic peroxide		Aspergillus metabolite;
GABA modulator;
mycotoxin;
Penicillium metabolite;
potassium channel blocker		00low000000
resolvin e2
0
diol;
hydroxy polyunsaturated fatty acid;
resolvin;
secondary allylic alcohol		anti-inflammatory agent;
human xenobiotic metabolite;
rat metabolite		00low000000
pamapimod
0
aromatic amine;
aromatic ether;
difluorobenzene;
diol;
primary alcohol;
pyridopyrimidine;
secondary amino compound		antirheumatic drug;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		00low000000
triptotriterpenic acid a
0
diol;
hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite00low000000
borrelidin
0
aliphatic nitrile;
diol;
macrolide;
monocarboxylic acid;
secondary alcohol		antifungal agent;
antimalarial;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
bacterial metabolite		00low000000
asperfuranone
0
2-benzofurans;
cyclic ketone;
diol;
polyketide;
secondary alcohol;
tertiary alcohol;
tertiary alpha-hydroxy ketone		antineoplastic agent;
fungal metabolite		00low000000
lancifodilactone g
0
cyclic ether;
diol;
enol;
gamma-lactone;
oxaspiro compound;
triterpenoid		anti-HIV agent;
metabolite		00low000000
pd 173074
0
aromatic amine;
biaryl;
dimethoxybenzene;
pyridopyrimidine;
tertiary amino compound;
ureas		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
fibroblast growth factor receptor antagonist		00low000000
amitrole
0
aromatic amine;
triazoles		carotenoid biosynthesis inhibitor;
EC 1.11.1.6 (catalase) inhibitor;
herbicide		00low000000
4-aminopyridine
0
aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker		00low000000
5-(n,n-hexamethylene)amiloride
0
aromatic amine;
azepanes;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines		antineoplastic agent;
apoptosis inducer;
odorant receptor antagonist;
sodium channel blocker		00low000000
ethylisopropylamiloride
0
aromatic amine;
guanidines;
monocarboxylic acid amide;
organochlorine compound;
pyrazines;
tertiary amino compound		anti-arrhythmia drug;
neuroprotective agent;
sodium channel blocker		00low000000
tacrine
0
acridines;
aromatic amine		EC 3.1.1.7 (acetylcholinesterase) inhibitor00low000000
tyrphostin ag957
0
aromatic amine00low000000
ambroxol
0
aromatic amine00low000000
dan 2163
0
aromatic amide;
aromatic amine;
benzamides;
pyrrolidines;
sulfone		environmental contaminant;
second generation antipsychotic;
xenobiotic		00low000000
antazoline
0
aromatic amine;
imidazolines;
tertiary amino compound		cholinergic antagonist;
H1-receptor antagonist;
xenobiotic		00low000000
cgs 15943
0
aromatic amine;
biaryl;
furans;
organochlorine compound;
primary amino compound;
quinazolines;
triazoloquinazoline		adenosine A1 receptor antagonist;
adenosine A2A receptor antagonist;
antineoplastic agent;
central nervous system stimulant		00low000000
chlorambucil
0
aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent		00low000000
diclofenac
0
amino acid;
aromatic amine;
dichlorobenzene;
monocarboxylic acid;
secondary amino compound		antipyretic;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
environmental contaminant;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic		00low000000
doxazosin
0
aromatic amine;
benzodioxine;
monocarboxylic acid amide;
N-acylpiperazine;
N-arylpiperazine;
quinazolines		alpha-adrenergic antagonist;
antihyperplasia drug;
antihypertensive agent;
antineoplastic agent;
vasodilator agent		00low000000
isothipendyl
0
aromatic amine;
tertiary amino compound		00low000000
lavendustin a
0
aromatic amine00low000000
2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid
0
aromatic amine00low000000
6-anilino-5,8-quinolinedione
0
aminoquinoline;
aromatic amine;
p-quinones;
quinolone		antineoplastic agent;
EC 4.6.1.2 (guanylate cyclase) inhibitor		00low000000
mafenide
0
aromatic amine00low000000
mesalamine
0
amino acid;
aromatic amine;
monocarboxylic acid;
monohydroxybenzoic acid;
phenols		non-steroidal anti-inflammatory drug00low000000
pargyline
0
aromatic amine00low000000
pd 153035
0
aromatic amine;
aromatic ether;
bromobenzenes;
quinazolines;
secondary amino compound		EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
epidermal growth factor receptor antagonist		00low000000
pd 158780
0
aromatic amine;
bromobenzenes;
diamine;
pyridopyrimidine;
secondary amino compound		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
pd 98059
0
aromatic amine;
monomethoxyflavone		EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector		00low000000
phenoxybenzamine
0
aromatic amine00low000000
ag 1879
0
aromatic amine;
monochlorobenzenes;
pyrazolopyrimidine		beta-adrenergic antagonist;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		00low000000
imatinib
0
aromatic amine;
benzamides;
N-methylpiperazine;
pyridines;
pyrimidines		antineoplastic agent;
apoptosis inducer;
tyrosine kinase inhibitor		00low000000
tripelennamine
0
aromatic amine00low000000
4-aminodiphenylamine
0
aromatic amine;
secondary amino compound		allergen00low000000
4,4'-diaminodiphenylmethane
0
aromatic amineallergen;
carcinogenic agent		00low000000
dibenzylamine
0
aromatic amine00low000000
benzoquinonium
0
aromatic amine00low000000
N-[(2-chlorophenyl)methyl]-1-[4-[[(2-chlorophenyl)methylamino]methyl]cyclohexyl]methanamine
0
aromatic amine00low000000
neutral red base
0
aromatic amine;
phenazines;
primary amino compound;
tertiary amino compound		acid-base indicator;
dye;
two-colour indicator		00low000000
diphenylamine
0
aromatic amine;
bridged diphenyl fungicide;
secondary amino compound		antifungal agrochemical;
antioxidant;
carotogenesis inhibitor;
EC 1.3.99.29 [phytoene desaturase (zeta-carotene-forming)] inhibitor;
ferroptosis inhibitor;
radical scavenger		00low000000
prothipendyl
0
aromatic amine;
tertiary amino compound		00low000000
guanazole
0
aromatic amine;
triazoles		antineoplastic agent;
DNA synthesis inhibitor;
EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor		00low000000
amiloride
0
aromatic amine;
guanidines;
organochlorine compound;
pyrazines		diuretic;
sodium channel blocker		00low000000
6-aminonicotinic acid
0
aminonicotinic acid;
aminopyridine;
aromatic amine		metabolite00low000000
trimetazidine
0
aromatic amine00low000000
oryzalin
0
aromatic amine;
C-nitro compound;
sulfonamide;
tertiary amino compound		agrochemical;
antimitotic;
herbicide		00low000000
2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline
0
aromatic amine;
imidazoquinoxaline		carcinogenic agent;
genotoxin;
Maillard reaction product;
mutagen		00low000000
acridine orange
0
aminoacridines;
aromatic amine;
tertiary amino compound		fluorochrome;
histological dye		00low000000
4-(diethylamino)benzaldehyde
0
aromatic amine;
benzaldehydes;
tertiary amino compound		EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor00low000000
dibenzthione
0
aromatic amine00low000000
8-azaadenine
0
aromatic amine;
nucleobase analogue;
triazolopyrimidines		EC 1.17.3.2 (xanthine oxidase) inhibitor;
Mycoplasma genitalium metabolite		00low000000
lamtidine
0
aromatic amine00low000000
bamipine
0
aromatic amine00low000000
methyl 3-aminopyrazine-2-carboxylate
0
aromatic amine;
methyl ester;
pyrazines		00low000000
p-Aminosalicylic acid methyl ester
0
aromatic amine00low000000
trimetazidine dihydrochloride
0
aromatic amine00low000000
phenylisopropyladenosine
0
aromatic amine;
benzenes;
hydrocarbyladenosine;
purine nucleoside;
secondary amino compound		adenosine A1 receptor agonist;
neuroprotective agent		00low000000
4-hydroxybenzylamine
0
aromatic amine00low000000
pomalidomide
0
aromatic amine;
dicarboximide;
isoindoles;
piperidones		angiogenesis inhibitor;
antineoplastic agent;
immunomodulator		00low000000
hydromethylthionine
0
aromatic amine;
phenothiazines;
tertiary amino compound		bacterial xenobiotic metabolite;
fluorochrome;
mouse metabolite;
rat metabolite		00low000000
8-amino-8-demethylriboflavin
0
aromatic amine;
benzopteridine;
primary amino compound;
tetrol		00low000000
aminopyralid
0
aromatic amine;
organochlorine pesticide;
pyridines		herbicide00low000000
lenalidomide
0
aromatic amine;
dicarboximide;
isoindoles;
piperidones		angiogenesis inhibitor;
antineoplastic agent;
immunomodulator		00low000000
5-aminonicotinic acid
0
aminonicotinic acid;
aminopyridine;
aromatic amine		metabolite00low000000
1-[4-[4-[(4-methylphenyl)methylamino]phenyl]-1-piperazinyl]ethanone
0
aromatic amine00low000000
4-[2-[[4-(dimethylamino)phenyl]methylamino]ethyl]-2,2-dimethyl-4-oxanol
0
aromatic amine00low000000
1-[4-[4-[(phenylmethyl)amino]phenyl]-1-piperazinyl]ethanone
0
aromatic amine00low000000
7-(2-methyl-2,3-dihydroindol-1-yl)-3-(phenylmethyl)triazolo[4,5-d]pyrimidine
0
aromatic amine;
tertiary amino compound		00low000000
1-(4-chlorophenyl)-N-(2-furanylmethyl)-N-[[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]methanamine
0
aromatic amine00low000000
N-[(1-cyclohexyl-5-tetrazolyl)-thiophen-2-ylmethyl]-N-(phenylmethyl)ethanamine
0
aromatic amine00low000000
5-[[4-(2-amino-2-oxoethoxy)-3-methoxyphenyl]methylamino]-2-(4-morpholinyl)benzoic acid
0
aromatic amine00low000000
5-(2-phenylethyl)-1,3,4-thiadiazol-2-amine
0
aromatic amine;
thiadiazoles		00low000000
iFSP1
0
aromatic amine;
nitrile;
primary amino compound;
pyridobenzimidazole;
toluenes		antineoplastic agent;
ferroptosis inducer;
ferroptosis suppressor protein 1 inhibitor		00low000000
N-(3-fluorophenyl)-2-(pyridin-4-yl)quinazolin-4-amine
0
aromatic amine;
monofluorobenzenes;
pyridines;
quinazolines;
secondary amino compound;
substituted aniline		00low000000
2-amino-4-(cyanomethyl)-6-(N-methylanilino)pyridine-3,5-dicarbonitrile
0
aromatic amine;
tertiary amino compound		00low000000
5-amino-3-(4-methoxyphenyl)-7-methyl-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid methyl ester
0
aromatic amine;
thiophenes		00low000000
4-[bis(phenylmethyl)amino]-2-(dimethylamino)-3-pyridinecarbonitrile
0
aromatic amine00low000000
2-[(3-fluorophenyl)methyl-(phenylmethyl)amino]ethanol
0
aromatic amine00low000000
2-methoxy-4-[[2-(methylthio)anilino]methyl]phenol
0
aromatic amine00low000000
1-(4-ethylphenyl)-N-(3-pyridinylmethyl)methanamine
0
aromatic amine00low000000
N-[(2,3-dimethoxyphenyl)methyl]-4-(4-methyl-1-piperidinyl)aniline
0
aromatic amine00low000000
2-amino-5-[diethylamino(oxo)methyl]-4-methyl-3-thiophenecarboxylic acid propan-2-yl ester
0
aromatic amine;
isopropyl ester;
tertiary carboxamide;
thiophenes		00low000000
4-(2,3-dihydro-1H-indol-1-yl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine
0
aromatic amine;
tertiary amino compound		00low000000
N-[(2-methoxyphenyl)methyl]-4-(1-piperidinyl)aniline
0
aromatic amine00low000000
4-[methyl-(4-thiophen-2-yl-2-thiazolyl)amino]phenol
0
aromatic amine;
tertiary amino compound		00low000000
N-[(3-bromo-4,5-diethoxyphenyl)methyl]-4-(4-morpholinyl)aniline
0
aromatic amine00low000000
4-[[5-chloro-2-[(4-fluorophenyl)methoxy]phenyl]methylamino]benzenesulfonamide
0
aromatic amine00low000000
2-[[2-[(2-fluorophenyl)methoxy]-3-methoxyphenyl]methylamino]phenol
0
aromatic amine00low000000
xl147
0
aromatic amine;
benzothiadiazole;
quinoxaline derivative;
sulfonamide		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor		00low000000
1-(4-acetyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-[[4-(difluoromethoxy)-3-methoxyphenyl]methyl-methylamino]ethanone
0
aromatic amine00low000000
(3-hydroxyphenyl)-[4-(phenylmethyl)-1-piperazinyl]methanethione
0
aromatic amine00low000000
N-[4-[(3-bromo-5-methoxy-4-prop-2-enoxyphenyl)methylamino]-2-methoxyphenyl]-2-methylpropanamide
0
aromatic amine00low000000
2-chloro-N-[4-(N-propan-2-ylanilino)phenyl]acetamide
0
aromatic amine;
tertiary amino compound		00low000000
6-[[(2-chlorophenyl)methyl-methylamino]methyl]-N2-(2-methylphenyl)-1,3,5-triazine-2,4-diamine
0
aromatic amine00low000000
2-chloro-1-[4-[(3-methylphenyl)methyl]-1-piperazinyl]ethanone
0
aromatic amine00low000000
N-{3-[(2-phenylquinazolin-4-yl)amino]phenyl}acetamide
0
acetamide;
aromatic amine;
quinazolines;
secondary amino compound;
substituted aniline		00low000000
1-(Benzylamino)-3-(3,4-dimethylphenoxy)propan-2-ol
0
aromatic amine00low000000
3-(4-ethyl-1-piperazinyl)-5-methylpyridazino[3,4-b][1,4]benzoxazine
0
aromatic amine;
tertiary amino compound		00low000000
5-amino-3-[[[1-(2-furanylmethyl)-5-oxo-3-pyrrolidinyl]-oxomethoxy]methyl]thiophene-2,4-dicarboxylic acid dimethyl ester
0
aromatic amine;
thiophenes		00low000000
1-(1-tert-butyl-5-tetrazolyl)-N-(phenylmethyl)-1-(3-pyridinyl)-N-(thiophen-2-ylmethyl)methanamine
0
aromatic amine00low000000
3-[[4,6-bis(4-morpholinyl)-1,3,5-triazin-2-yl]amino]-3-(2-chlorophenyl)propanoic acid ethyl ester
0
1,3,5-triazines;
aromatic amine		00low000000
2-(N-ethylanilino)-4-thieno[3,2-d][1,3]thiazinone
0
aromatic amine;
tertiary amino compound		00low000000
N4-ethyl-N6,1,2-trimethyl-N4-phenylpyrimidin-1-ium-4,6-diamine
0
aromatic amine;
tertiary amino compound		00low000000
N-(3-{[2-(2-fluorophenyl)quinazolin-4-yl]amino}phenyl)acetamide
0
acetamide;
aromatic amine;
monofluorobenzenes;
quinazolines;
secondary amino compound;
substituted aniline		00low000000
N-(1-benzylpiperidin-4-yl)-2-(pyridin-3-yl)quinazolin-4-amine
0
aromatic amine;
piperidines;
pyridines;
quinazolines;
secondary amino compound;
tertiary amino compound		00low000000
5-nitro-2-[(phenylmethyl)amino]benzoic acid [2-(cyclohexylamino)-2-oxoethyl] ester
0
aromatic amine00low000000
GSK3-XIII
0
aromatic amine;
pyrazoles;
quinazolines;
secondary amino compound		EC 2.7.11.26 (tau-protein kinase) inhibitor00low000000
b 43
0
aromatic amine;
aromatic ether;
cyclopentanes;
primary amino compound;
pyrrolopyrimidine		EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor;
geroprotector		00low000000
2-(1-adamantyl)-4-chloro-5-[(4-fluorophenyl)methylamino]-3-pyridazinone
0
aromatic amine00low000000
1-cyclohexyl-3-[1-[4-(phenylmethyl)-1-piperazinyl]-1-thiophen-2-ylpropan-2-yl]urea
0
aromatic amine00low000000
r 115866
0
aromatic amine;
benzothiazoles;
secondary amino compound;
triazoles		00low000000
nsc 716970
0
aromatic amine;
aromatic ether;
indolecarboxamide;
organochlorine compound		antineoplastic agent00low000000
n-methylbenzylamine hydrochloride
0
aromatic amine00low000000
pi103
0
aromatic amine;
morpholines;
organic heterotricyclic compound;
phenols;
tertiary amino compound		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor		00low000000
selexipag
0
aromatic amine;
ether;
monocarboxylic acid amide;
N-sulfonylcarboxamide;
pyrazines;
tertiary amino compound		orphan drug;
platelet aggregation inhibitor;
prodrug;
prostacyclin receptor agonist;
vasodilator agent		00low000000
mre 269
0
aromatic amine;
ether;
monocarboxylic acid;
pyrazines;
sulfonamide;
tertiary amino compound		drug metabolite;
orphan drug;
platelet aggregation inhibitor;
prostacyclin receptor agonist;
vasodilator agent		00low000000
sch 51344
0
aromatic amine;
aromatic ether;
primary alcohol;
pyrazoloquinoline;
secondary amino compound		antineoplastic agent00low000000
ageladine a
0
alkaloid;
aromatic amine;
imidazopyridine;
organobromine compound;
pyrroles		angiogenesis inhibitor;
antineoplastic agent;
matrix metalloproteinase inhibitor;
metabolite		00low000000
azd2858
0
aromatic amine;
N-methylpiperazine;
pyrazines;
pyridines;
secondary carboxamide;
sulfonamide		antineoplastic agent;
bone density conservation agent;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
Wnt signalling activator		00low000000
4-aminopyridine-3-methanol
0
aminopyridine;
aromatic amine;
aromatic primary alcohol		potassium channel blocker00low000000
ethaboxam
0
1,3-thiazoles;
aromatic amide;
aromatic amine;
nitrile;
secondary amino compound;
thiophenes		00low000000
abt-737
0
aromatic amine;
aryl sulfide;
biphenyls;
C-nitro compound;
monochlorobenzenes;
N-arylpiperazine;
N-sulfonylcarboxamide;
secondary amino compound;
tertiary amino compound		anti-allergic agent;
anti-inflammatory agent;
antineoplastic agent;
apoptosis inducer;
B-cell lymphoma 2 inhibitor		00low000000
abt 869
0
aromatic amine;
indazoles;
phenylureas		angiogenesis inhibitor;
antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
gw9508
0
aromatic amine00low000000
idelalisib
0
aromatic amine;
organofluorine compound;
purines;
quinazolines;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor		00low000000
trametinib
0
acetamides;
aromatic amine;
cyclopropanes;
organofluorine compound;
organoiodine compound;
pyridopyrimidine;
ring assembly		anticoronaviral agent;
antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor;
geroprotector		00low000000
ametoctradin
0
aromatic amine;
triazolopyrimidines		antifungal agrochemical;
mitochondrial cytochrome-bc1 complex inhibitor		00low000000
vizamyl
0
(18)F radiopharmaceutical;
aromatic amine;
benzothiazoles;
secondary amino compound		radioactive imaging agent00low000000
2-[(2-chloro-4-nitroanilino)methyl]-6-methoxyphenol
0
aromatic amine00low000000
[(2S,4S)-4-(4-bromophenyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-3,4-dihydro-2H-pyran-6-yl]-[4-(phenylmethyl)-1-piperazinyl]methanone
0
aromatic amine00low000000
gdc-0973
0
aromatic amine;
difluorobenzene;
N-acylazetidine;
organoiodine compound;
piperidines;
secondary amino compound;
tertiary alcohol		antineoplastic agent;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor		00low000000
gsk690693
0
1,2,5-oxadiazole;
acetylenic compound;
aromatic amine;
aromatic ether;
imidazopyridine;
piperidines;
primary amino compound;
tertiary alcohol		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor		00low000000
3-[[2-(4-bromophenyl)-1-oxoethyl]amino]-3-[4-[(4-fluorophenyl)methylamino]-3-nitrophenyl]propanamide
0
aromatic amine00low000000
2-[4-[(4-cyclopentyloxyphenyl)methyl]-1-propan-2-yl-2-piperazinyl]ethanol
0
aromatic amine00low000000
pci 32765
0
acrylamides;
aromatic amine;
aromatic ether;
N-acylpiperidine;
pyrazolopyrimidine;
tertiary carboxamide		antineoplastic agent;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor		00low000000
PP121
0
aromatic amine;
cyclopentanes;
pyrazolopyrimidine;
pyrrolopyridine		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
tyrosine kinase inhibitor		00low000000
asp3026
0
aromatic amine;
diamino-1,3,5-triazine;
monomethoxybenzene;
N-methylpiperazine;
piperidines;
secondary amino compound;
sulfone		antimalarial;
antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor;
EC 6.1.1.6 (lysine--tRNA ligase) inhibitor		00low000000
1-[4-[4-[(3-methylphenyl)methylamino]phenyl]-1-piperazinyl]ethanone
0
aromatic amine00low000000
mrt67307
0
aromatic amine00low000000
GS-441524
0
aromatic amine;
C-nucleoside;
nitrile;
pyrrolotriazine		anticoronaviral agent;
antiviral agent;
drug metabolite		00low000000
lrrk2-in1
0
aromatic amine;
aromatic ether;
N-acylpiperidine;
N-alkylpiperazine;
pyrimidobenzodiazepine;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor		00low000000
gilteritinib
0
aromatic amine;
monomethoxybenzene;
N-methylpiperazine;
oxanes;
piperidines;
primary carboxamide;
pyrazines;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor		00low000000
ML240
0
aromatic amine;
aromatic ether;
benzimidazoles;
primary amino compound;
quinazolines;
secondary amino compound		antineoplastic agent00low000000
xl765
0
aromatic amine;
aromatic ether;
benzamides;
quinoxaline derivative;
sulfonamide		antineoplastic agent;
EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor;
mTOR inhibitor		00low000000
GS-443902
0
aromatic amine;
C-nucleoside;
nitrile;
organic triphosphate;
pyrrolotriazine		anticoronaviral agent;
antiviral drug;
drug metabolite		00low000000
acp-196
0
aromatic amine;
benzamides;
imidazopyrazine;
pyridines;
pyrrolidinecarboxamide;
secondary carboxamide;
tertiary carboxamide;
ynone		antineoplastic agent;
apoptosis inducer;
EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor		00low000000
ly3009120
0
aminotoluene;
aromatic amine;
biaryl;
monofluorobenzenes;
phenylureas;
pyridopyrimidine;
secondary amino compound		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
B-Raf inhibitor;
necroptosis inhibitor		00low000000
enasidenib
0
1,3,5-triazines;
aminopyridine;
aromatic amine;
organofluorine compound;
secondary amino compound;
tertiary alcohol		antineoplastic agent;
EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor		00low000000
s 8932
0
aromatic amine;
C-nucleoside;
carboxylic ester;
nitrile;
phosphoramidate ester;
pyrrolotriazine		anticoronaviral agent;
antiviral drug;
prodrug		00low000000
can 508
0
aromatic amine;
monoazo compound;
phenols;
pyrazoles		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor		00low000000
tirapazamine
0
aromatic amine;
benzotriazines;
N-oxide		antibacterial agent;
antineoplastic agent;
apoptosis inducer		00low000000
pp242
0
aromatic amine;
biaryl;
hydroxyindoles;
phenols;
primary amino compound;
pyrazolopyrimidine		antineoplastic agent;
mTOR inhibitor		00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
butyric acid
0
fatty acid 4:0;
straight-chain saturated fatty acid		human urinary metabolite;
Mycoplasma genitalium metabolite		00low000000
methanol
0
alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite		00low000000
chloramphenicol
0
C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor		00low000000
cumene hydroperoxide
0
peroxolenvironmental contaminant;
Mycoplasma genitalium metabolite;
oxidising agent		00low000000
2-phenyl-2-propanol
0
benzyl alcohols;
tertiary alcohol		human xenobiotic metabolite;
Mycoplasma genitalium metabolite		00low000000
difloxacin
0
fluoroquinolone antibiotic;
monocarboxylic acid;
monofluorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
quinolone antibiotic;
quinolone		antibacterial drug;
Mycoplasma genitalium metabolite		00low000000
isodialuric acid
0
hydroxypyrimidine;
nucleobase analogue;
pyrimidone		Mycoplasma genitalium metabolite00low000000
cifostodine
0
2',3'-cyclic pyrimidine nucleotideEscherichia coli metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite		00low000000
6-azathymine
0
1,2,4-triazines;
cyclic ketone;
nucleobase analogue		EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitor;
Mycoplasma genitalium metabolite		00low000000
tyrosyltyrosine
0
tyrosyltyrosineMycoplasma genitalium metabolite00low000000
8-azaadenine
0
aromatic amine;
nucleobase analogue;
triazolopyrimidines		EC 1.17.3.2 (xanthine oxidase) inhibitor;
Mycoplasma genitalium metabolite		00low000000
leucylleucine
0
dipeptide;
L-aminoacyl-L-amino acid zwitterion		human metabolite;
Mycoplasma genitalium metabolite		00low000000
Trp-Trp
0
dipeptideMycoplasma genitalium metabolite00low000000
valylvaline
0
dipeptideMycoplasma genitalium metabolite00low000000
2-deoxyglucose-6-phosphate
0
deoxyaldohexose phosphateEscherichia coli metabolite;
Mycoplasma genitalium metabolite		00low000000
lysyllysine
0
dipeptideMycoplasma genitalium metabolite00low000000
2'-deoxycytidine diphosphate
0
2'-deoxycytidine phosphate;
pyrimidine 2'-deoxyribonucleoside 5'-diphosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite		00low000000
arginylarginine
0
dipeptideMycoplasma genitalium metabolite00low000000
cysteinylcysteine
0
dipeptideMycoplasma genitalium metabolite00low000000
5,6-dihydrothymidine
0
pyrimidine 2'-deoxyribonucleosideMycoplasma genitalium metabolite00low000000
glutamyl-glutamic acid
0
dipeptideMycoplasma genitalium metabolite00low000000
adenosine 5'-phosphoramidate
0
organic phosphoramidateMycoplasma genitalium metabolite00low000000
aspartyl-aspartic acid
0
dipeptideMycoplasma genitalium metabolite00low000000
5-(carboxymethylaminomethyl)-2-thiouridine
0
glycine derivative;
thiouridine		Mycoplasma genitalium metabolite00low000000
tryptophyl adenylate
0
adenosine 5'-phosphate;
alpha-amino acid ester;
L-tryptophan derivative;
purine ribonucleoside 5'-monophosphate		Mycoplasma genitalium metabolite00low000000
n-palmitoylsphingosine
0
Cer(d34:1);
N-acylsphingosine;
N-palmitoyl-sphingoid base		human blood serum metabolite;
Mycoplasma genitalium metabolite		00low000000
menaquinone 7
0
menaquinonebone density conservation agent;
cofactor;
Escherichia coli metabolite;
human blood serum metabolite;
Mycoplasma genitalium metabolite		00low000000
streptogramin a
0
1,3-oxazoles;
cyclic ketone;
enamide;
lactam;
macrolide antibiotic;
macrolide;
pyrroline;
secondary alcohol;
secondary carboxamide;
tertiary carboxamide		antibacterial drug;
Mycoplasma genitalium metabolite		00low000000
alanylalanine
0
dipeptide zwitterion;
dipeptide		Mycoplasma genitalium metabolite00low000000
phenylalanylphenylalanine
0
dipeptide;
L-aminoacyl-L-amino acid zwitterion		human blood serum metabolite;
Mycoplasma genitalium metabolite		00low000000
histidylhistidine
0
dipeptideMycoplasma genitalium metabolite00low000000
cyclic diadenosine phosphate
0
adenyl ribonucleotide;
cyclic purine dinucleotide		Mycoplasma genitalium metabolite00low000000
prolyl-proline
0
dipeptidehuman urinary metabolite;
Mycoplasma genitalium metabolite		00low000000
s-adenosylmethionine
0
organic cation;
sulfonium compound		coenzyme;
cofactor;
human metabolite;
micronutrient;
Mycoplasma genitalium metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite		00low000000
deoxyinosine monophosphate
0
deoxyinosine phosphate;
purine 2'-deoxyribonucleoside 5'-monophosphate		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite		00low000000
deoxydiguanosine diphosphosphate
0
5'-phospho-(3'->5')-dinucleotide;
single-stranded DNA oligonucleotide		Mycoplasma genitalium metabolite00low000000
8,5'-cyclo-2'-deoxyguanosine
0
aromatic amine;
bridged compound;
diol;
N-glycosyl compound;
organic heterotetracyclic compound		Mycoplasma genitalium metabolite00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
chloramphenicol
0
C-nitro compound;
carboxamide;
diol;
organochlorine compound		antibacterial drug;
antimicrobial agent;
Escherichia coli metabolite;
geroprotector;
Mycoplasma genitalium metabolite;
protein synthesis inhibitor		00low000000
8-azaadenine
0
aromatic amine;
nucleobase analogue;
triazolopyrimidines		EC 1.17.3.2 (xanthine oxidase) inhibitor;
Mycoplasma genitalium metabolite		00low000000
8,5'-cyclo-2'-deoxyguanosine
0
aromatic amine;
bridged compound;
diol;
N-glycosyl compound;
organic heterotetracyclic compound		Mycoplasma genitalium metabolite00low000000
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
formic acid
1
monocarboxylic acidantibacterial agent;
astringent;
metabolite;
protic solvent;
solvent		2007200717.0low000100
thymidine
1
pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite		2011201113.0low000010
deoxyuridine
1
pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		2011201113.0low000010
2'-deoxyadenosine
3
purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		2009201911.0low000120
manganese
1
elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient		201820186.0low000010
pyrimidine dimers
1
2007200717.0low000100
5-formyl-2'-deoxyuridine
1
2011201113.0low000010
4,6-diamino-5-n-formamidopyrimidine
2
aminopyrimidine;
formamidopyrimidine		2007201115.0low000110
8-oxo-dado
1
2011201113.0low000010
hydroxyl radical
4
oxygen hydride;
oxygen radical;
reactive oxygen species		2008201712.8low000220
fenton's reagent
1
2013201311.0low000010
thioguanine anhydrous
1
2-aminopurinesanticoronaviral agent;
antimetabolite;
antineoplastic agent		2013201311.0low000010
dinoprost
1
monocarboxylic acid;
prostaglandins Falpha		human metabolite;
mouse metabolite		201620168.0low000010
8-epi-prostaglandin f2alpha
1
F2-isoprostanebiomarker;
bronchoconstrictor agent;
vasoconstrictor agent		201620168.0low000010
deoxyribose
1
deoxypentosehuman metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		1995199529.0low001000
8-oxo-2'-deoxyadenosine
2
purine 2'-deoxyribonucleoside2007200717.0low000200
oligonucleotides
8
199920229.8medium001142
5-hydroxymethyl-2'-deoxyuridine
1
2011201113.0low000010
deoxyguanosine
18
purine 2'-deoxyribonucleoside;
purines 2'-deoxy-D-ribonucleoside		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		1988202112.8high0112131
guanine
2
2-aminopurines;
oxopurine;
purine nucleobase		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite		2010201113.5low000110
8-hydroxyguanine
2
oxopurine2010201113.5low000110
8-hydroxy-2'-deoxyguanosine
2
guanosinesbiomarker2008201612.0low000110
8,5'-cyclo-2'-deoxyguanosine
15
aromatic amine;
bridged compound;
diol;
N-glycosyl compound;
organic heterotetracyclic compound		Mycoplasma genitalium metabolite1988201913.5high0111120
phosphorus radioisotopes
2
2001201516.0low000110
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Aging0
1
2007200717.0low000100
Atherogenesis0
1
2012201212.0low000010
Atherosclerosis0
1
2012201212.0low000010
Breast Cancer0
2
2007201712.0low000110
Breast Neoplasms0
2
2007201712.0low000110
Cancer of Skin0
1
201720177.0low000010
Cell Transformation, Neoplastic0
1
2010201014.0low000100
Cockayne Syndrome0
1
2009200915.0low000100
Colorectal Cancer0
1
2011201113.0low000010
Colorectal Neoplasms0
1
2011201113.0low000010
Cytomegalovirus0
1
2002200222.0low000100
Degenerative Diseases, Central Nervous System0
1
201720177.0low000010
Diabetes Mellitus, Adult-Onset0
1
201620168.0low000010
Diabetes Mellitus, Type 20
1
201620168.0low000010
Kaposi Disease0
4
2000201717.5medium001210
Neurodegenerative Diseases0
1
201720177.0low000010
Prediabetes0
1
201620168.0low000010
Prediabetic State0
1
201620168.0low000010
Sensitivity and Specificity0
1
2001200123.0low000100
Skin Neoplasms0
1
201720177.0low000010
Xeroderma Pigmentosum0
4
2000201717.5medium001210