Proteins > acid sphingomyelinase
Page last updated: 2024-08-08 00:29:02

acid sphingomyelinase

[no definition available]

Synonyms

Research

Bioassay Publications (0)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0)18.7374
1990's0 (0)18.2507
2000's0 (0)29.6817
2010's0 (0)24.3611
2020's0 (0)2.80

Compounds (831)

Drugs with Potency Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
1,3-dipropyl-8-(4-sulfophenyl)xanthineHomo sapiens (human)Potency25.118910
1,5-dihydroxyisoquinolineHomo sapiens (human)Potency31.622810
1-anilino-8-naphthalenesulfonateHomo sapiens (human)Potency25.118910
5-(n,n-hexamethylene)amilorideHomo sapiens (human)Potency31.622810
ethylisopropylamilorideHomo sapiens (human)Potency25.118910
amlodipineHomo sapiens (human)Potency31.622810
benzo(a)pyreneHomo sapiens (human)Potency25.118910
bufexamacHomo sapiens (human)Potency7.079510
5,7-dimethoxycoumarinHomo sapiens (human)Potency25.118910
amberlite cg 400Homo sapiens (human)Potency25.118910
dipyridamoleHomo sapiens (human)Potency25.118910
ellipticineHomo sapiens (human)Potency25.118910
ethoxyquinHomo sapiens (human)Potency25.118910
etidronateHomo sapiens (human)Potency14.125410
felodipineHomo sapiens (human)Potency25.118910
doxorubicin hydrochlorideHomo sapiens (human)Potency25.118910
metolazoneHomo sapiens (human)Potency31.622810
pomiferinHomo sapiens (human)Potency79.432810
silymarinHomo sapiens (human)Potency100.000010
terazosinHomo sapiens (human)Potency25.118910
vincaHomo sapiens (human)Potency31.622810
methyldimethylaminoazobenzeneHomo sapiens (human)Potency1,412.540010
9,10-dimethyl-1,2-benzanthraceneHomo sapiens (human)Potency25.118910
p-aminoazobenzeneHomo sapiens (human)Potency79.432810
ampicillinHomo sapiens (human)Potency70.794610
quinethazoneHomo sapiens (human)Potency31.622810
1-phenylazo-2-naphthylamineHomo sapiens (human)Potency89.125110
methyl n-methylanthranilateHomo sapiens (human)Potency25.118910
7-amino-4-hydroxy-2-naphthalenesulfonic acidHomo sapiens (human)Potency31.622810
1-naphthylphenylamineHomo sapiens (human)Potency25.118910
pyronineHomo sapiens (human)Potency10.000010
dehydrothio-4-toluidineHomo sapiens (human)Potency25.118910
5-amino-2-naphthalenesulfonateHomo sapiens (human)Potency25.118910
benzethonium chlorideHomo sapiens (human)Potency112.202010
pyrazolanthroneHomo sapiens (human)Potency25.118910
3-amino-9-ethylcarbazoleHomo sapiens (human)Potency31.622810
2-Phenylethyl 2-aminobenzoateHomo sapiens (human)Potency25.118910
peucedaninHomo sapiens (human)Potency25.118910
neozoneHomo sapiens (human)Potency25.118910
sterogenolHomo sapiens (human)Potency56.234110
1,2-dihydro-2,2,4-trimethylquinolineHomo sapiens (human)Potency25.118910
fluorantheneHomo sapiens (human)Potency31.622810
benz(c)acridineHomo sapiens (human)Potency31.622810
thioxanthoneHomo sapiens (human)Potency31.622810
myristic acidHomo sapiens (human)Potency223.872010
2-anthramineHomo sapiens (human)Potency39.810710
dicarbethoxydihydrocollidineHomo sapiens (human)Potency25.118910
erythromycinHomo sapiens (human)Potency70.794610
2'-deoxy-5'-adenosine monophosphateHomo sapiens (human)Potency31.622810
laudanosineHomo sapiens (human)Potency19.952610
amiloride hydrochloride, anhydrousHomo sapiens (human)Potency15.848910
amilorideHomo sapiens (human)Potency25.118910
ethyl violetHomo sapiens (human)Potency39.810710
6-chrysenamineHomo sapiens (human)Potency31.622810
6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinolineHomo sapiens (human)Potency31.622810
n-methylisatoic anhydrideHomo sapiens (human)Potency31.622810
marmesin, (r)-isomerHomo sapiens (human)Potency31.622810
9-chloromethylanthraceneHomo sapiens (human)Potency25.118910
wr 171,699Homo sapiens (human)Potency44.668410
10-carboxymethyl-9-acridanoneHomo sapiens (human)Potency10.000010
terazosin hydrochloride anhydrousHomo sapiens (human)Potency25.118910
amlodipine besylateHomo sapiens (human)Potency25.118910
topotecan hydrochlorideHomo sapiens (human)Potency15.848910
trazodone hydrochlorideHomo sapiens (human)Potency19.952610
doxazosin mesylateHomo sapiens (human)Potency25.118910
xanthotoxolHomo sapiens (human)Potency25.118910
xanthyletineHomo sapiens (human)Potency31.622810
xanthoxyletinHomo sapiens (human)Potency25.118910
pyrrolo(1,2-a)quinoxalineHomo sapiens (human)Potency25.118910
harmolHomo sapiens (human)Potency25.118910
11h-pyrido(2,1-b)quinazolin-11-oneHomo sapiens (human)Potency25.118910
prazosin hydrochlorideHomo sapiens (human)Potency31.622810
miconazole nitrateHomo sapiens (human)Potency891.251010
n-(2-carboxyphenyl)glycineHomo sapiens (human)Potency25.118910
etidinHomo sapiens (human)Potency25.118910
2-MethoxyxanthoneHomo sapiens (human)Potency31.622810
honokiolHomo sapiens (human)Potency316.228010
9-aminocamptothecinHomo sapiens (human)Potency15.848910
coumarin 153Homo sapiens (human)Potency15.848910
methyl 3-aminopyrazine-2-carboxylateHomo sapiens (human)Potency25.118910
nodakeninHomo sapiens (human)Potency25.118910
OroseloneHomo sapiens (human)Potency25.118910
N-(4-ethoxyphenyl)-3-hydroxy-2-naphthalenecarboxamideHomo sapiens (human)Potency39.810710
2-(1H-benzimidazol-2-yl)anilineHomo sapiens (human)Potency15.848910
2-butyl-6-(butylamino)-1h-benzo(de)isoquinoline-1,3(2h)-dioneHomo sapiens (human)Potency89.125110
mephentermineHomo sapiens (human)Potency89.125110
adenosine 5'-methylenediphosphateHomo sapiens (human)Potency63.095710
columbianetin, (s)-isomerHomo sapiens (human)Potency25.118910
corynanthineHomo sapiens (human)Potency25.118910
methylene bis(methylanthranilate)Homo sapiens (human)Potency25.118910
osajinHomo sapiens (human)Potency70.794610
4-chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acidHomo sapiens (human)Potency100.000010
3,5,7,3',4'-pentamethoxyflavoneHomo sapiens (human)Potency25.118910
6-methoxyflavanoneHomo sapiens (human)Potency25.118910
diiodobenzotepaHomo sapiens (human)Potency3.981110
6,6'-methylene bis(2,2,4-trimethyl-1,2-dihydroquinoline)Homo sapiens (human)Potency31.622810
diphyllinHomo sapiens (human)Potency39.810710
7,9-dimethyl-9aH-quinolizine-1,2,3,4-tetracarboxylic acid tetramethyl esterHomo sapiens (human)Potency25.118910
moxifloxacin hydrochlorideHomo sapiens (human)Potency25.118910
bicuculline methiodideHomo sapiens (human)Potency31.622810
methotrexateHomo sapiens (human)Potency31.622810
alpha-ergocryptineHomo sapiens (human)Potency31.622810
nsc-141549Homo sapiens (human)Potency19.952610
4,5-diphenyl-4-oxazolin-2-oneHomo sapiens (human)Potency19.952610
tetrahydroharmineHomo sapiens (human)Potency39.810710
metralindole monohydrochlorideHomo sapiens (human)Potency25.118910
abt 980Homo sapiens (human)Potency112.202010
4-methoxy-1-vinylcarbolineHomo sapiens (human)Potency25.118910
moracin mHomo sapiens (human)Potency25.118910
1-(1-pyrrolidinylmethyl)-2-naphtholHomo sapiens (human)Potency25.118910
2-[(2-methoxy-2-oxoethyl)thio]benzoic acid methyl esterHomo sapiens (human)Potency25.118910
ml 204Homo sapiens (human)Potency31.622810
6-methyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrileHomo sapiens (human)Potency31.622810
raubasineHomo sapiens (human)Potency31.622810
n-acetyl-1-aminopyreneHomo sapiens (human)Potency31.622810
methyl reserpateHomo sapiens (human)Potency19.952610
a-301Homo sapiens (human)Potency19.952610
7-Acetoxy-2-methylisoflavoneHomo sapiens (human)Potency25.118910
1',3'-dimethylspiro[1H-indole-3,8'-7,9-dihydropurine]-2,2',6'-trioneHomo sapiens (human)Potency7.943310
11,12-dihydro-4-methoxydibenz(b,f)(1,4)oxazepine-8-carboxylateHomo sapiens (human)Potency31.622810
7-methoxycoumarin-4-acetic acidHomo sapiens (human)Potency25.118910
3-phenyl-1H-quinoxalin-2-oneHomo sapiens (human)Potency31.622810
7-benzoyl-3-chloroindolizine-1,2-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency25.118910
1-methyl-3-phenylpyrazino[1,2-a]benzimidazoleHomo sapiens (human)Potency25.118910
nsc 674495Homo sapiens (human)Potency25.118910
nsc 680410Homo sapiens (human)Potency281.838010
7-(4-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidineHomo sapiens (human)Potency19.952610
18-Hydroxy-11,17-dimethoxyyohimban-16-carboxylic acidHomo sapiens (human)Potency19.952610
amiodarone hydrochlorideHomo sapiens (human)Potency39.810710
dihydroergocristine monomesylateHomo sapiens (human)Potency25.118910
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diolHomo sapiens (human)Potency25.118910
6-bromoindirubin-3'-oximeHomo sapiens (human)Potency141.254010
meso-dihydroguaiaretic acidHomo sapiens (human)Potency112.202010
4-(2,3-Dihydroxy-3-methylbutoxy)furo(3,2-g)chromen-7-oneHomo sapiens (human)Potency31.622810
3-methoxycinnolineHomo sapiens (human)Potency25.118910
2-(3-oxo-4H-quinoxalin-2-yl)propanoic acid ethyl esterHomo sapiens (human)Potency31.622810
4,7-dimethoxy-2,3-dihydroinden-1-oneHomo sapiens (human)Potency31.622810
2-amino-3-cyano-5,6,7,8-tetrahydroquinoline-4-carboxylic acid methyl esterHomo sapiens (human)Potency25.118910
NeobyakangelicolHomo sapiens (human)Potency25.118910
2-chlorothioxanthen-9-oneHomo sapiens (human)Potency31.622810
2,3-diphenyl-6-quinoxalinecarboxylic acidHomo sapiens (human)Potency31.622810
sinapinic acidHomo sapiens (human)Potency25.118910
piperineHomo sapiens (human)Potency31.622810
averufinHomo sapiens (human)Potency316.228010
calmidazoliumHomo sapiens (human)Potency56.234110
N-(2-fluorophenyl)-2-(3-methoxyphenyl)imino-3-methyl-4-oxo-1,3-thiazinane-6-carboxamideHomo sapiens (human)Potency501.187010
6-amino-2-methyl-8-phenyl-1,6,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrileHomo sapiens (human)Potency25.118910
3-[(1-cyclopentyl-5-tetrazolyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methyl]-7-methoxy-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
2-(2,5-dimethoxyphenyl)-5-(5-methyl-2-furanyl)-1,3,4-oxadiazoleHomo sapiens (human)Potency25.118910
1-[3-(dimethylamino)propyl]-3-(4-fluorophenyl)-1-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]ureaHomo sapiens (human)Potency25.118910
LSM-19079Homo sapiens (human)Potency25.118910
4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid ethyl esterHomo sapiens (human)Potency31.622810
5-(1,3-benzodioxol-5-yl)-N-(2-furanylmethyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
5-hydroxy-N,N-dimethyl-2-phenyl-3-benzofurancarboxamideHomo sapiens (human)Potency25.118910
11-[2-(4-morpholinyl)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrileHomo sapiens (human)Potency25.118910
3-(benzenesulfonyl)-2-imino-1-(2-oxolanylmethyl)-5-dipyrido[1,2-d-3',4'-f]pyrimidinoneHomo sapiens (human)Potency25.118910
N-[(6-ethoxy-2-oxo-1H-quinolin-3-yl)methyl]-4-fluoro-N-(2-hydroxyethyl)benzamideHomo sapiens (human)Potency25.118910
2-(1-benzimidazolylmethyl)-5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazoleHomo sapiens (human)Potency125.892010
3-[1-azepanyl-[1-(phenylmethyl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
5-[3-(dimethylamino)phenyl]-N-methyl-1,3,4-thiadiazol-2-amineHomo sapiens (human)Potency25.118910
7-[[1-(2-oxolanylmethyl)-5-tetrazolyl]-(1-pyrrolidinyl)methyl]-5H-[1,3]dioxolo[4,5-g]quinolin-6-oneHomo sapiens (human)Potency19.952610
2-[[3-cyano-6-(2-furanyl)-4-(trifluoromethyl)-2-pyridinyl]thio]propanoic acid ethyl esterHomo sapiens (human)Potency25.118910
N-[2,5-dimethoxy-4-[[oxo(thiophen-2-yl)methyl]amino]phenyl]-2-furancarboxamideHomo sapiens (human)Potency39.810710
haplamineHomo sapiens (human)Potency31.622810
6-methyl-2-[4-[oxo(thiophen-2-yl)methyl]-1-piperazinyl]-3-quinolinecarbonitrileHomo sapiens (human)Potency25.118910
5,7-dimethyl-2-(1-pyrrolidinyl)-3-quinolinecarbonitrileHomo sapiens (human)Potency31.622810
3-cyclohexyl-1-[(7-oxo-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-8-yl)methyl]-1-[2-(1-pyrrolidinyl)ethyl]ureaHomo sapiens (human)Potency25.118910
6-(4-hydroxy-3-methoxyphenyl)-4-methoxy-1,3-dimethyl-8-cyclohepta[c]furanoneHomo sapiens (human)Potency125.892010
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methylphenyl)propanamideHomo sapiens (human)Potency31.622810
2-[[2-(1-azepanyl)-2-oxoethyl]thio]-6-methoxy-3-quinolinecarbonitrileHomo sapiens (human)Potency25.118910
N-[2-[(3-cyano-6-ethoxy-2-quinolinyl)amino]ethyl]propanamideHomo sapiens (human)Potency25.118910
8-[2-(4-methoxyphenyl)-5-phenyl-7-pyrazolo[1,5-a]pyrimidinyl]-1,4-dioxa-8-azaspiro[4.5]decaneHomo sapiens (human)Potency25.118910
3-[2-hydroxyethyl-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]sulfamoyl]benzoic acid ethyl esterHomo sapiens (human)Potency25.118910
2-acetyl-6-amino-8-(2-phenylethyl)-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrileHomo sapiens (human)Potency31.622810
6-methoxy-3-[[[1-(2-methoxyethyl)-5-tetrazolyl]methyl-(3-pyridinylmethyl)amino]methyl]-1H-quinolin-2-oneHomo sapiens (human)Potency31.622810
1-(3-cyano-7-methoxy-2-quinolinyl)-4-piperidinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
3-[3,4-dihydro-1H-isoquinolin-2-yl-[1-(2-methylbutan-2-yl)-5-tetrazolyl]methyl]-7-methoxy-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
3-(2-chlorophenyl)-1-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-1-[2-(1-pyrrolidinyl)ethyl]ureaHomo sapiens (human)Potency25.118910
N-[(1,3-dimethyl-4-pyrazolyl)methyl]-5-(2-furanyl)-N-methyl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
8-[(1-tert-butyl-5-tetrazolyl)-thiomorpholin-4-ylmethyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-oneHomo sapiens (human)Potency19.952610
2-(2,5-dimethoxyphenyl)-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazoleHomo sapiens (human)Potency25.118910
5-(4-fluorophenyl)-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxylic acid methyl esterHomo sapiens (human)Potency19.952610
N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)butanamideHomo sapiens (human)Potency31.622810
1-[1-[[1-[(4-methylphenyl)methyl]-5-tetrazolyl]methyl]-4-piperidinyl]-5-(trifluoromethyl)benzotriazoleHomo sapiens (human)Potency112.202010
3-[1-azepanyl-[1-[(4-fluorophenyl)methyl]-5-tetrazolyl]methyl]-6,7-dimethoxy-1H-quinolin-2-oneHomo sapiens (human)Potency31.622810
9-[3-(4-acetyl-3,5-dimethyl-1-pyrazolyl)-2-hydroxypropyl]-6-methyl-3,4-dihydro-2H-carbazol-1-oneHomo sapiens (human)Potency25.118910
N-[(6,7-dimethoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(3-hydroxypropyl)benzenesulfonamideHomo sapiens (human)Potency25.118910
1-[(6,7-dimethoxy-2-oxo-1H-quinolin-3-yl)methyl]-3-(phenylmethyl)-1-(3-pyridinylmethyl)ureaHomo sapiens (human)Potency25.118910
4-methyl-6-(methylthio)-1H-quinolin-2-oneHomo sapiens (human)Potency31.622810
2-[[4-(3,4-dimethoxyphenyl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]-N-(5-methyl-3-isoxazolyl)acetamideHomo sapiens (human)Potency25.118910
N,N-diethyl-2-[(3-thiophen-2-yl-7-isothiazolo[4,5-d]pyrimidinyl)thio]acetamideHomo sapiens (human)Potency25.118910
N-(2,1,3-benzothiadiazol-4-yl)-3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxamideHomo sapiens (human)Potency25.118910
4-[2-(4-fluorophenyl)-5-phenyl-7-pyrazolo[1,5-a]pyrimidinyl]morpholineHomo sapiens (human)Potency25.118910
4-amino-N5-[1-(2-furanyl)-2-(3-methylbutylamino)-2-oxoethyl]-N5-(2-methoxyphenyl)isothiazole-3,5-dicarboxamideHomo sapiens (human)Potency31.622810
6-methoxy-3-[[[1-(2-oxolanylmethyl)-5-tetrazolyl]methyl-(2-phenylethyl)amino]methyl]-1H-quinolin-2-oneHomo sapiens (human)Potency25.118910
4-amino-N5-[2-(2-methoxyethylamino)-1-(5-methyl-2-furanyl)-2-oxoethyl]-N5-(thiophen-2-ylmethyl)isothiazole-3,5-dicarboxamideHomo sapiens (human)Potency25.118910
4-[(3-cyano-4,6-dimethyl-2-pyridinyl)thio]-3-oxobutanoic acid propan-2-yl esterHomo sapiens (human)Potency25.118910
N-[4-(4-fluorophenyl)-2-thiazolyl]-2-[(4-methylphenyl)sulfonylamino]benzamideHomo sapiens (human)Potency25.118910
1-cyclohexyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-amineHomo sapiens (human)Potency19.952610
1-amino-5-(4-morpholinyl)-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxylic acid ethyl esterHomo sapiens (human)Potency7.943310
2-[2-hydroxy-6,7-dimethoxy-4-(4-morpholinyl)-1-naphthalenyl]-N-phenylacetamideHomo sapiens (human)Potency19.952610
8-(2-furanyl)-6-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-3,3-dimethyl-1,4-dihydrothiopyrano[3,4-c]pyridine-5-carbonitrileHomo sapiens (human)Potency25.118910
7-methyl-3-(4-morpholinyl)-1-(prop-2-enylamino)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrileHomo sapiens (human)Potency7.943310
2-amino-1-(1,3-benzodioxol-5-yl)-N-[2-(4-morpholinyl)ethyl]-3-pyrrolo[3,2-b]quinoxalinecarboxamideHomo sapiens (human)Potency25.118910
7-diethylaminocoumarin-3-carboxylic acidHomo sapiens (human)Potency25.118910
6-[2-(dimethylamino)ethylamino]-8-(2-furanyl)-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrileHomo sapiens (human)Potency25.118910
2-cyano-N-(3-methoxypropyl)-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetamideHomo sapiens (human)Potency25.118910
LSM-27020Homo sapiens (human)Potency25.118910
4-(3-amino-5-bromo-2-benzofuranyl)-4-oxobutanoic acid methyl esterHomo sapiens (human)Potency25.118910
1-[3-[1-cyano-2-oxo-2-[(phenylmethyl)amino]ethyl]-2-quinoxalinyl]-3-piperidinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
1-[7-(2,4-dichlorophenyl)-5-methyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethanoneHomo sapiens (human)Potency25.118910
4-amino-5,8-dimethoxy-2-(1,1,2,2,2-pentafluoroethyl)-3-quinolinecarbonitrileHomo sapiens (human)Potency25.118910
2-[(6-amino-3,5-dicyano-4-thiophen-2-yl-2-pyridinyl)thio]-N-(2-phenylethyl)acetamideHomo sapiens (human)Potency31.622810
N-ethyl-2-imino-10-methyl-1-[(4-methylphenyl)methyl]-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideHomo sapiens (human)Potency12.589310
2-(4-chlorophenyl)-5-(1-piperidinyl)-4-oxazolecarbonitrileHomo sapiens (human)Potency31.622810
1-methyl-2-[(phenylthio)methyl]-3-indolecarbonitrileHomo sapiens (human)Potency199.526010
5-(4-methoxyphenyl)-7-phenyl-[1,2,4]triazolo[1,5-a]pyrimidineHomo sapiens (human)Potency25.118910
LSM-23818Homo sapiens (human)Potency25.118910
arachinHomo sapiens (human)Potency125.892010
2-(4-chlorophenyl)-3-(2-furanylmethyl)imidazo[4,5-b]quinoxalineHomo sapiens (human)Potency31.622810
5-methyl-6-pyridin-4-yl-6H-benzimidazolo[1,2-c]quinazolineHomo sapiens (human)Potency25.118910
5-(2,4-dimethoxyphenyl)-7-(3,4-dimethoxyphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidineHomo sapiens (human)Potency31.622810
3-methyl-N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamideHomo sapiens (human)Potency25.118910
N-(1-propyl-3-pyrazolo[3,4-b]quinolinyl)butanamideHomo sapiens (human)Potency31.622810
LSM-32147Homo sapiens (human)Potency25.118910
2-cyano-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetic acid hexyl esterHomo sapiens (human)Potency630.957010
LSM-23602Homo sapiens (human)Potency15.848910
N-[7-(2-chlorophenyl)-5-(4-methoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-methoxyacetamideHomo sapiens (human)Potency25.118910
3-(ethylaminomethyl)-6-methyl-1H-quinolin-2-oneHomo sapiens (human)Potency39.810710
4-(1H-benzimidazol-2-ylmethylthio)-2-methylbenzofuro[3,2-d]pyrimidineHomo sapiens (human)Potency89.125110
N-(1,8-dimethyl-3-pyrazolo[3,4-b]quinolinyl)propanamideHomo sapiens (human)Potency25.118910
2-[4-[(4-chlorophenyl)methoxy]phenyl]-5-[3-(1-imidazolyl)propylamino]-4-oxazolecarbonitrileHomo sapiens (human)Potency89.125110
2-(3-methylphenyl)sulfonyl-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetonitrileHomo sapiens (human)Potency25.118910
2-methoxy-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methoxyphenyl)acetamideHomo sapiens (human)Potency25.118910
N-[7-(4-chlorophenyl)-5-(4-methoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-methoxyacetamideHomo sapiens (human)Potency25.118910
N-(1-ethyl-7-methyl-3-pyrazolo[3,4-b]quinolinyl)-2-furancarboxamideHomo sapiens (human)Potency25.118910
1-(thiophen-2-ylmethyl)-3-thiophen-2-ylsulfonyl-2-pyrrolo[3,2-b]quinoxalinamineHomo sapiens (human)Potency25.118910
N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-(4-methylphenyl)-2-oxolanecarboxamideHomo sapiens (human)Potency25.118910
N-butyl-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-2-pyridinecarboxamideHomo sapiens (human)Potency25.118910
N-(1,7-dimethyl-3-pyrazolo[3,4-b]quinolinyl)acetamideHomo sapiens (human)Potency25.118910
3-[[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-oxoethyl]amino]-5-ethoxy-1H-indole-2-carboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
9,10-dimethoxy-2-(2-pyridinylmethylamino)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-oneHomo sapiens (human)Potency25.118910
N-[5-(4-chlorophenyl)-7-(4-methoxyphenyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-2-furancarboxamideHomo sapiens (human)Potency89.125110
3-[[2-(3,5-dimethyl-1-pyrazolyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl]amino]-1-propanolHomo sapiens (human)Potency31.622810
3-(4-methoxyphenyl)-6-[(4-methylphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleHomo sapiens (human)Potency100.000010
1-[1-oxo-2-[(4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-7-yl)oxy]ethyl]-4-piperidinecarboxylic acidHomo sapiens (human)Potency31.622810
LSM-32980Homo sapiens (human)Potency25.118910
7-methyl-3-(3-methylbutylamino)-1-(1-pyrrolidinyl)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrileHomo sapiens (human)Potency25.118910
LSM-20899Homo sapiens (human)Potency25.118910
3-(1-benzimidazolylmethyl)-6-[(4-methoxyphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleHomo sapiens (human)Potency251.189010
5-(4-methoxyphenyl)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylic acidHomo sapiens (human)Potency31.622810
3,3',4,5'-tetrahydroxystilbeneHomo sapiens (human)Potency25.118910
N-(1,3-dioxo-2-phenyl-5-isoindolyl)-2-thiophenecarboxamideHomo sapiens (human)Potency25.118910
2-amino-4-(5-methyl-2-furanyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrileHomo sapiens (human)Potency25.118910
1-(diethylamino)-3-methyl-4-pyrido[1,2-a]benzimidazolecarbonitrileHomo sapiens (human)Potency25.118910
3-(4-nitrophenyl)-2H-phthalazine-1,4-dioneHomo sapiens (human)Potency79.432810
4,6-dimethyl-N-phenyl-2-quinolinamineHomo sapiens (human)Potency25.118910
7-(diethylamino)-2-oxo-1-benzopyran-3-carbonitrileHomo sapiens (human)Potency12.589310
4-(3-amino-2-imidazo[1,2-a]pyridinyl)-2-methoxyphenolHomo sapiens (human)Potency19.952610
6-(2-methyl-3-benzofuranyl)-2,3-dihydroimidazo[2,1-b]thiazoleHomo sapiens (human)Potency15.848910
N4-(3-chlorophenyl)-6-methyl-N2-(phenylmethyl)pyrimidine-2,4-diamineHomo sapiens (human)Potency70.794610
1-(3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinyl)ethanoneHomo sapiens (human)Potency25.118910
iFSP1Homo sapiens (human)Potency25.118910
3-methyl-N-[4-(4-oxo-3,1-benzoxazin-2-yl)phenyl]butanamideHomo sapiens (human)Potency31.622810
5-methyl-4-[(2-oxo-1-benzopyran-7-yl)oxymethyl]-2-furancarboxylic acid methyl esterHomo sapiens (human)Potency25.118910
2-(3,4-dichlorophenyl)imidazo[1,2-a]pyrimidineHomo sapiens (human)Potency31.622810
4-[2-(dimethylamino)ethylamino]-3-benzo[h]quinolinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
6-methoxy-2-oxo-N-(3-pyridinylmethyl)-1-benzopyran-3-carboxamideHomo sapiens (human)Potency25.118910
vu0038882Homo sapiens (human)Potency31.622810
7,9-dibromo-3,4-dihydropyrido[2,1-c][1,2,4]thiadiazine 2,2-dioxideHomo sapiens (human)Potency25.118910
4-(1H-benzimidazol-2-yl)quinolineHomo sapiens (human)Potency25.118910
6-amino-5-(methylamino)-1-(phenylmethyl)pyrimidine-2,4-dioneHomo sapiens (human)Potency25.118910
N,N-diethyl-2-oxo-1H-benzo[cd]indole-6-sulfonamideHomo sapiens (human)Potency25.118910
5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidineHomo sapiens (human)Potency31.622810
(4-Methyl-2-oxochromen-7-yl) furan-2-carboxylateHomo sapiens (human)Potency7.943310
3-[(6-methyl-4-phenyl-2-quinazolinyl)amino]propanoic acidHomo sapiens (human)Potency25.118910
acetic acid (4-oxo-3-phenyl-1-benzopyran-7-yl) esterHomo sapiens (human)Potency25.118910
LSM-21110Homo sapiens (human)Potency31.622810
7,7-dimethyl-2-(1-pyrrolidinyl)-5,8-dihydropyrano[4,3-b]pyridine-3-carbonitrileHomo sapiens (human)Potency25.118910
2-(4-fluorophenyl)-8-methylindolizineHomo sapiens (human)Potency25.118910
3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinecarboxylic acid methyl esterHomo sapiens (human)Potency25.118910
2-methyl-N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)propanamideHomo sapiens (human)Potency25.118910
N-[2-(4-methoxyphenyl)-5-benzotriazolyl]butanamideHomo sapiens (human)Potency31.622810
6-methyl-4-(trifluoromethyl)-7,8,9,10-tetrahydropyrano[2,3-f]quinolin-2-oneHomo sapiens (human)Potency25.118910
(3-methyl-1-phenyl-5-thieno[2,3-c]pyrazolyl)-(3-methyl-1-pyrazolyl)methanoneHomo sapiens (human)Potency12.589310
3-(8-methyl-2-imidazo[1,2-a]pyridinyl)-1-benzopyran-2-oneHomo sapiens (human)Potency19.952610
N-(1-methyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-yl)-2-(1-pyrrolidinyl)acetamideHomo sapiens (human)Potency25.118910
N-[7-(1-oxopropyl)-2,3-dihydro-1,4-benzodioxin-6-yl]benzamideHomo sapiens (human)Potency12.589310
4-(6-methyl-4-phenyl-2-quinazolinyl)-1-piperazinecarboxaldehydeHomo sapiens (human)Potency25.118910
2-methoxy-4-[[2-(methylthio)anilino]methyl]phenolHomo sapiens (human)Potency25.118910
6-(4-morpholinyl)naphthalene-2,3-dicarbonitrileHomo sapiens (human)Potency25.118910
2-(3-cyano-4,5,6-trimethyl-1H-pyridin-2-ylidene)propanedinitrileHomo sapiens (human)Potency31.622810
2-(2,4-dimethylphenyl)-5-benzotriazolamineHomo sapiens (human)Potency25.118910
4-tert-butyl-N-(1,4-dioxo-2,3-dihydrophthalazin-5-yl)benzamideHomo sapiens (human)Potency31.622810
(4-Ethyl-2-oxochromen-7-yl) furan-2-carboxylateHomo sapiens (human)Potency12.589310
2-(2,5-dimethylphenyl)-3H-benzimidazol-5-amineHomo sapiens (human)Potency25.118910
6-methyl-4-oxoquinolizine-1,3-dicarboxylic acid diethyl esterHomo sapiens (human)Potency31.622810
2-chloro-5-methyl-1-oxo-3-phenyl-4-pyrido[1,2-a]benzimidazolecarbonitrileHomo sapiens (human)Potency31.622810
1-[[4-(2-pyridinyl)-1-piperazinyl]methyl]-2-benzo[cd]indoloneHomo sapiens (human)Potency31.622810
LSM-20487Homo sapiens (human)Potency25.118910
2-[[4-(1-pyrrolidinylsulfonyl)phenyl]hydrazinylidene]propanedinitrileHomo sapiens (human)Potency281.838010
3-methyl-5-propyl-7-furo[3,2-g][1]benzopyranoneHomo sapiens (human)Potency25.118910
N-(4-fluorophenyl)-1-(3-methylphenyl)-4-pyrazolo[3,4-d]pyrimidinamineHomo sapiens (human)Potency630.957010
3-amino-6-cyclopropyl-4-(4-methoxyphenyl)-2-thieno[2,3-b]pyridinecarbonitrileHomo sapiens (human)Potency31.622810
5-(1-methyl-2-benzimidazolyl)-2-thiophenecarboxaldehydeHomo sapiens (human)Potency25.118910
N-(2-methyl-1,3-dioxo-5-isoindolyl)-1-naphthalenecarboxamideHomo sapiens (human)Potency25.118910
4-(4-morpholinylmethyl)-3-quinolinolHomo sapiens (human)Potency25.118910
2-amino-9-ethyl-3-pyrido[2,3-b]indolecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
8-chloro-7-propan-2-yloxy-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-4-oneHomo sapiens (human)Potency31.622810
5-(4-morpholinyl)-2-thiophen-2-yl-4-oxazolecarbonitrileHomo sapiens (human)Potency25.118910
6-methoxy-4-methyl-2-[(2-methylphenyl)methylthio]quinazolineHomo sapiens (human)Potency31.622810
3-[5-(4-methoxyphenyl)-1-prop-2-enyl-2-pyrrolyl]propanoic acidHomo sapiens (human)Potency31.622810
[2-(5-methyl-2-thiophenyl)-4-quinolinyl]-(1-pyrrolidinyl)methanoneHomo sapiens (human)Potency25.118910
3-(3,5-dimethyl-7-oxo-6-furo[3,2-g][1]benzopyranyl)propanoic acidHomo sapiens (human)Potency19.952610
7-methoxy-2-oxo-1-benzopyran-3-carboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
7,8-dichloropyrido[1,2-a]benzimidazoleHomo sapiens (human)Potency25.118910
2-(2-furanyl)-3-(4-methylphenyl)imidazo[4,5-b]quinoxalineHomo sapiens (human)Potency3.981110
3-(2-benzo[cd]indolylamino)benzoic acidHomo sapiens (human)Potency31.622810
N-[6-methyl-1-(2-methylpropyl)-3-pyrazolo[3,4-b]quinolinyl]-2-furancarboxamideHomo sapiens (human)Potency25.118910
3-(isopropylideneamino)-2,2-dimethyl-2,3-dihydroquinazolin-4(1h)-oneHomo sapiens (human)Potency25.118910
3-amino-4-thiophen-2-yl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxylic acid methyl esterHomo sapiens (human)Potency25.118910
2-(2-fluorophenyl)-5-(4-methoxyanilino)-4-oxazolecarbonitrileHomo sapiens (human)Potency25.118910
terazosinHomo sapiens (human)Potency25.118910
1-(4-methyl-2-oxo-1-benzopyran-7-yl)-3-(2-pyridinylmethyl)thioureaHomo sapiens (human)Potency25.118910
N-[(1-ethyl-2-oxo-6-benzo[cd]indolyl)sulfonyl]-N-(4-methoxyphenyl)-3-pyridinecarboxamideHomo sapiens (human)Potency31.622810
umi-77Homo sapiens (human)Potency70.794610
N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-(3-methyl-N-methylsulfonylanilino)acetamideHomo sapiens (human)Potency25.118910
2-[(3-cyano-4-phenyl-6-thiophen-2-yl-2-pyridinyl)thio]-N-propan-2-ylacetamideHomo sapiens (human)Potency25.118910
2-[9-(4-methoxyphenyl)-1,8-dioxo-3,4,5,6,7,9-hexahydro-2H-acridin-10-yl]acetic acidHomo sapiens (human)Potency25.118910
6-chloro-4-phenyl-3-(1-phenyl-5-tetrazolyl)quinolineHomo sapiens (human)Potency501.187010
2-[3-(4-methoxyphenyl)-1-benzo[f]quinolinyl]acetic acid ethyl esterHomo sapiens (human)Potency25.118910
4-[[[2,3-bis(2-pyridinyl)-6-quinoxalinyl]amino]-oxomethyl]-1-piperazinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
1-[(4-fluorophenyl)methyl]-4-(3,4,5-trimethoxyphenyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency25.118910
1-(3,4-dichlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)ureaHomo sapiens (human)Potency2.511910
N-cyclopentyl-2-imino-1-[3-(4-morpholinyl)propyl]-5-oxo-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
N-(2-methoxyphenyl)-5-methyl-3-[(2-methylphenyl)methyl]-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamideHomo sapiens (human)Potency12.589310
2-[[3-cyano-6-(2-furanyl)-4-(trifluoromethyl)-2-pyridinyl]thio]-N,N-diethylacetamideHomo sapiens (human)Potency31.622810
2-(2,4,5-trimethoxyphenyl)-1,3-benzothiazoleHomo sapiens (human)Potency31.622810
5-(4-bromophenyl)-2-phenyl-7-pyrazolo[1,5-a]pyrimidinamineHomo sapiens (human)Potency31.622810
N-(3-methylphenyl)-4-tetrazolo[1,5-a]quinoxalinamineHomo sapiens (human)Potency39.810710
[3-amino-4-(methoxymethyl)-6-methyl-2-thieno[2,3-b]pyridinyl]-(4-phenyl-1-piperazinyl)methanoneHomo sapiens (human)Potency25.118910
[7-(difluoromethyl)-5-(4-methoxyphenyl)-3-pyrazolo[1,5-a]pyrimidinyl]-(1-piperidinyl)methanoneHomo sapiens (human)Potency25.118910
1-[(3,4-dimethoxyphenyl)methyl]-4-(4-hydroxyphenyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency25.118910
N-(2-furanylmethyl)-5-(4-methoxyphenyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
N-(2-furanylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
2-(3,4-dimethoxyphenyl)-8-methoxy-4,4-dimethyl-5H-isothiazolo[5,4-c]quinoline-1-thioneHomo sapiens (human)Potency125.892010
5-(3,4-dimethoxyphenyl)-N-(2-furanylmethyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
4-morpholinyl-[5-thiophen-2-yl-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinyl]methanoneHomo sapiens (human)Potency25.118910
6-ethyl-2-thieno[2,3-b]quinolinecarboxylic acidHomo sapiens (human)Potency25.118910
N-(6-acetyl-1,3-benzodioxol-5-yl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]acetamideHomo sapiens (human)Potency25.118910
2-[(3-cyano-6-methoxy-2-quinolinyl)thio]-N-(2-methyl-1,3-benzothiazol-5-yl)acetamideHomo sapiens (human)Potency25.118910
3-[[4-(1,3-benzodioxol-5-yl)-6-(trifluoromethyl)-2-pyrimidinyl]thio]-N-(2-furanylmethyl)propanamideHomo sapiens (human)Potency31.622810
2-(6-amino-2-methyl-4-oxo-3-quinazolinyl)-N-(2-methylphenyl)acetamideHomo sapiens (human)Potency25.118910
6-amino-3-[(2-chlorophenyl)methyl]-2-propyl-4-quinazolinoneHomo sapiens (human)Potency25.118910
2-(3-methylphenyl)-N-[4-(4-morpholinyl)phenyl]-4-quinazolinamineHomo sapiens (human)Potency112.202010
N-(2-ethylphenyl)-2-[[2-(4-methoxyphenyl)-4-oxo-1-benzopyran-6-yl]oxy]acetamideHomo sapiens (human)Potency31.622810
4-(4-anilinoanilino)-2-quinazolinecarboxylic acid ethyl esterHomo sapiens (human)Potency70.794610
1-ethyl-2-oxo-N-(2-pyridinylmethyl)-6-benzo[cd]indolesulfonamideHomo sapiens (human)Potency25.118910
2-[(4-methyl-2-oxo-1-benzopyran-7-yl)oxy]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)acetamideHomo sapiens (human)Potency25.118910
10-(4-methoxyphenyl)-3,4,5,6,7,9-hexahydro-2H-acridine-1,8-dioneHomo sapiens (human)Potency15.848910
N-(2-phenylethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxamideHomo sapiens (human)Potency31.622810
3-imino-2-benzo[f][1]benzopyrancarbothioamideHomo sapiens (human)Potency25.118910
5-bromo-2-furancarboxylic acid (3-benzamidophenyl) esterHomo sapiens (human)Potency316.228010
2-[(3-cyano-6-methyl-2-pyridinyl)thio]-N-(2-thiazolyl)acetamideHomo sapiens (human)Potency31.622810
LSM-16526Homo sapiens (human)Potency25.118910
LSM-28559Homo sapiens (human)Potency25.118910
N-(3,5-dichlorophenyl)-2-(methanesulfonamido)benzamideHomo sapiens (human)Potency25.118910
7-(2-oxopropoxy)-3-phenyl-1-benzopyran-2-oneHomo sapiens (human)Potency25.118910
3-thiophen-2-ylimidazo[1,5-a]pyridineHomo sapiens (human)Potency25.118910
N-(2,4-dimethoxyphenyl)-2-(1-pyrrolidinyl)-4-quinazolinamineHomo sapiens (human)Potency25.118910
N-(2-furanylmethyl)-2-imino-5-oxo-1-(2-phenylethyl)-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamideHomo sapiens (human)Potency31.622810
N-[6-(diethylsulfamoyl)-1,3-benzothiazol-2-yl]-2-thiophenecarboxamideHomo sapiens (human)Potency100.000010
N-(4-fluorophenyl)-3-([1,2,4]triazolo[4,3-a]quinolin-1-ylthio)propanamideHomo sapiens (human)Potency25.118910
2-[[4-cyano-6,6,7-trimethyl-1-(4-morpholinyl)-5,8-dihydro-2,7-naphthyridin-3-yl]thio]acetic acid methyl esterHomo sapiens (human)Potency25.118910
N-cyclohexyl-2-[(8-methoxy-6-oxo-3-benzo[c][1]benzopyranyl)oxy]acetamideHomo sapiens (human)Potency31.622810
2-imino-10-methyl-N-[2-(4-morpholinyl)ethyl]-5-oxo-1-(3-pyridinylmethyl)-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
2-methylsulfonyl-4,6-diphenyl-3-thieno[2,3-b]pyridinamineHomo sapiens (human)Potency25.118910
2-[[5-(3-aminophenyl)-4-methyl-1,2,4-triazol-3-yl]thio]-1-(9H-fluoren-2-yl)ethanoneHomo sapiens (human)Potency501.187010
[2-(4-methoxyphenyl)-6-methyl-4-quinolinyl]-(4-morpholinyl)methanoneHomo sapiens (human)Potency25.118910
3-(3-oxo-2-benzo[f][1]benzopyranyl)-1-phenyl-4-pyrazolecarboxaldehydeHomo sapiens (human)Potency7.943310
N-(2-phenyl-5-benzotriazolyl)-2,3-dihydro-1,4-benzodioxin-6-carboxamideHomo sapiens (human)Potency19.952610
3-(3,4-dimethoxyphenyl)-7-(2-oxopropoxy)-1-benzopyran-2-oneHomo sapiens (human)Potency25.118910
1-(2-fluorophenyl)-3-[5-(2-fluorophenyl)-1,3,4-thiadiazol-2-yl]ureaHomo sapiens (human)Potency12.589310
N-[6-methoxy-1-(2-methylpropyl)-3-pyrazolo[3,4-b]quinolinyl]-3-methylbutanamideHomo sapiens (human)Potency25.118910
3-bromo-5-[[4-[hydroxy(diphenyl)methyl]-1-piperidinyl]-oxomethyl]-2-pyranoneHomo sapiens (human)Potency25.118910
8,9-dimethyl-N-(3-methylphenyl)-3-[2-(4-morpholinyl)ethyl]-4H-[1,3]thiazino[6,5-b]quinolin-2-imineHomo sapiens (human)Potency56.234110
7-(4-ethyl-1-piperazinyl)-2-(3-fluorophenyl)-5-phenylpyrazolo[1,5-a]pyrimidineHomo sapiens (human)Potency25.118910
3-amino-8-methyl-N-[4-(4-morpholinyl)phenyl]-2-thieno[2,3-b]quinolinecarboxamideHomo sapiens (human)Potency89.125110
7-methyl-2-[4-(4-methylphenyl)sulfonyl-1,4-diazepan-1-yl]-3-quinolinecarbonitrileHomo sapiens (human)Potency25.118910
7-methoxy-2-[4-[(2-methylphenyl)-oxomethyl]-1-piperazinyl]-3-quinolinecarbonitrileHomo sapiens (human)Potency31.622810
(2,6-difluorophenyl)-[4-(5-fluoro-2-methyl-1-benzimidazolyl)-1-piperidinyl]methanoneHomo sapiens (human)Potency25.118910
2-[(3-chlorophenyl)methyl]-6-phenyl-5-(1-piperidinyl)-3-pyridazinoneHomo sapiens (human)Potency630.957010
4-(4-tert-butylphenoxy)-5-methoxy-2-phenylpyrimidineHomo sapiens (human)Potency177.828010
3-[5-[(4-chlorophenyl)methylthio]-1,3,4-oxadiazol-2-yl]-1-(phenylmethyl)-2-pyridinoneHomo sapiens (human)Potency31.622810
5-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-2-phenylthiazoleHomo sapiens (human)Potency25.118910
5-[1-[(4-fluorophenyl)methyl]-3-pyrazolyl]-2-phenylthiazoleHomo sapiens (human)Potency25.118910
6-(4-methyl-1-piperazinyl)-2-(3,4,5-trimethoxyphenyl)-1H-benzimidazoleHomo sapiens (human)Potency25.118910
6-tert-butyl-2-oxo-4-(trifluoromethyl)-1H-pyridine-3-carbonitrileHomo sapiens (human)Potency25.118910
2-(4-methylsulfonylphenyl)-6-imidazo[1,2-a]pyridinecarboxylic acid methyl esterHomo sapiens (human)Potency31.622810
4-(2-quinoxalinylamino)benzoic acid ethyl esterHomo sapiens (human)Potency25.118910
2-(benzenesulfonylmethyl)-5-(4-chlorophenyl)cyclohexane-1,3-dioneHomo sapiens (human)Potency1.995310
3-(5-chloro-1,3-benzoxazol-2-yl)-N-(phenylmethyl)-2-pyridinamineHomo sapiens (human)Potency25.118910
2-[(2,4-dichlorophenyl)methylthio]-6,7-dimethoxy-3-(thiophen-2-ylmethyl)-4-quinazolinimineHomo sapiens (human)Potency112.202010
5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamideHomo sapiens (human)Potency100.000010
7-methyl-4-oxo-2-[(phenylmethyl)amino]-3-pyrido[1,2-a]pyrimidinecarboxaldehydeHomo sapiens (human)Potency25.118910
LSM-19448Homo sapiens (human)Potency25.118910
11-[2-(diethylamino)ethylamino]-7,8,9,10-tetrahydrobenzimidazolo[1,2-b]isoquinoline-6-carbonitrileHomo sapiens (human)Potency31.622810
auraptenHomo sapiens (human)Potency31.622810
1-[[1-oxo-2-[[5-(phenylmethylthio)-1,3,4-thiadiazol-2-yl]thio]ethyl]amino]-3-phenylthioureaHomo sapiens (human)Potency199.526010
1-ethyl-N-[3-(4-morpholinyl)propyl]-2-oxo-6-benzo[cd]indolesulfonamideHomo sapiens (human)Potency25.118910
2-chloro-4,6-diphenyl-5-pyrimidinamineHomo sapiens (human)Potency25.118910
5-[(4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-7-yl)oxymethyl]-2-furancarboxylic acidHomo sapiens (human)Potency31.622810
umbellipreninHomo sapiens (human)Potency31.622810
4-[[[1-oxo-2-[(2-oxo-3-phenyl-1-benzopyran-7-yl)oxy]ethyl]amino]methyl]-1-cyclohexanecarboxylic acidHomo sapiens (human)Potency25.118910
3-(3-hydroxypropylamino)-7-methyl-1-(pentylamino)-6,8-dihydro-5H-2,7-naphthyridine-4-carbonitrileHomo sapiens (human)Potency31.622810
2-[[(4-methyl-1-piperazinyl)-sulfanylidenemethyl]amino]benzene-1,4-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency19.952610
5-bromo-N-(2-fluorophenyl)-6-oxo-3-pyrancarboxamideHomo sapiens (human)Potency25.118910
5-tert-butyl-3-(4-chlorophenyl)-N-(2-pyridinylmethyl)-7-pyrazolo[1,5-a]pyrimidinamineHomo sapiens (human)Potency31.622810
2-amino-4-[[2-(4-bromophenyl)-2-oxoethyl]thio]-3-azaspiro[5.5]undeca-1,4-diene-1,5-dicarbonitrileHomo sapiens (human)Potency316.228010
2-amino-1-[2-(4-morpholinyl)ethyl]-3-pyrrolo[3,2-b]quinoxalinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
6-methyl-7-[2-nitro-4-(trifluoromethyl)phenoxy]-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-4-oneHomo sapiens (human)Potency25.118910
N-[3-(benzenesulfonyl)-1-cyclohexyl-2-pyrrolo[3,2-b]quinoxalinyl]benzenesulfonamideHomo sapiens (human)Potency31.622810
3-[(6-methyl-4-phenyl-2-quinazolinyl)amino]-1-propanolHomo sapiens (human)Potency25.118910
3-amino-N-(2-fluorophenyl)-6-(2-furanyl)-2-thieno[2,3-b]pyridinecarboxamideHomo sapiens (human)Potency31.622810
N-[4-[[3-(4-sulfamoylanilino)-2-quinoxalinyl]sulfamoyl]phenyl]acetamideHomo sapiens (human)Potency25.118910
N-(1-ethyl-6-methyl-3-pyrazolo[3,4-b]quinolinyl)-2-(4-methoxyphenyl)acetamideHomo sapiens (human)Potency19.952610
2-[[1-oxo-2-(2-pyrimidinylthio)ethyl]amino]-6-(phenylmethyl)-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
4-(3,4-dimethoxyphenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl esterHomo sapiens (human)Potency25.118910
3-(4-methylphenyl)sulfonylpropanoic acid [2-[(3,5-dichloro-2-pyridinyl)amino]-2-oxoethyl] esterHomo sapiens (human)Potency31.622810
N-(4,5-dihydrothiazol-2-yl)-2-thiophen-2-yl-4-quinolinecarboxamideHomo sapiens (human)Potency31.622810
2-(4-methoxyphenyl)-4-quinolinecarboxylic acid [2-oxo-2-(propan-2-ylamino)ethyl] esterHomo sapiens (human)Potency25.118910
2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxo-5-pyrimidinyl]-2-oxoethyl] esterHomo sapiens (human)Potency31.622810
2-[2-[[5-cyano-1-(3-methoxypropyl)-6-oxo-3-pyridinyl]-oxomethyl]-4-methoxyphenoxy]-N-(5-methyl-3-isoxazolyl)acetamideHomo sapiens (human)Potency19.952610
[4-(5-chloro-2-methylphenyl)-1-piperazinyl]-(2-ethoxy-3-pyridinyl)methanoneHomo sapiens (human)Potency79.432810
3-methyl-6-thiophen-2-yl-4-isoxazolo[5,4-b]pyridinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
N-[3-(6-methyl-4-phenyl-2-quinolinyl)phenyl]methanesulfonamideHomo sapiens (human)Potency112.202010
4-[2-[[3-(4-methylphenyl)-5-triazolo[1,5-a]quinazolinyl]amino]ethyl]benzenesulfonamideHomo sapiens (human)Potency12.589310
N-[(4-methoxyphenyl)methyl]-2-methyl-4,9-dioxo-3-benzo[f]benzofurancarboxamideHomo sapiens (human)Potency1,584.890010
2-[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]-oxomethyl]imino-1-(2-methylpropyl)-5-oxo-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
3-[[(2,3-dimethylanilino)-sulfanylidenemethyl]amino]-1H-indole-2-carboxylic acid ethyl esterHomo sapiens (human)Potency19.952610
LSM-26967Homo sapiens (human)Potency25.118910
2-[2-furanyl(oxo)methyl]imino-5-oxo-1-propan-2-yl-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxylic acid ethyl esterHomo sapiens (human)Potency31.622810
1-(2,3-dimethyl-6-quinoxalinyl)-3-(3-hydroxypropyl)thioureaHomo sapiens (human)Potency25.118910
N-[5-(3-methoxyphenyl)-1,3,4-thiadiazol-2-yl]-2-thiophenecarboxamideHomo sapiens (human)Potency25.118910
N-[2-(1-naphthalenyl)-1,3-benzoxazol-5-yl]-1H-1,2,4-triazole-5-carboxamideHomo sapiens (human)Potency25.118910
3-[1-(3-methoxypropyl)-5-thiophen-2-yl-2-pyrrolyl]propanoic acidHomo sapiens (human)Potency25.118910
4-methyl-N-(2-phenylphenyl)-3-(phenylsulfamoyl)benzamideHomo sapiens (human)Potency891.251010
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(5,7-diphenyl-2-pyrazolo[1,5-a]pyrimidinyl)methanoneHomo sapiens (human)Potency25.118910
N-(2,1,3-benzothiadiazol-4-yl)-5-(3-chlorophenyl)-2-furancarboxamideHomo sapiens (human)Potency15.848910
3,4-dimethoxy-N-[4-(2,2,3,3-tetrafluoropropoxy)-3-(trifluoromethyl)phenyl]benzamideHomo sapiens (human)Potency112.202010
reversanHomo sapiens (human)Potency25.118910
2-(4-methoxyphenyl)-N-[2-(4-morpholinyl)ethyl]-4-quinolinecarboxamideHomo sapiens (human)Potency25.118910
5,7-dimethyl-N-phenyl-2-pyrazolo[1,5-a]pyrimidinamineHomo sapiens (human)Potency25.118910
N-[4-[(4,6-dimethyl-2-pyrimidinyl)sulfamoyl]phenyl]-2-phenyl-4-quinolinecarboxamideHomo sapiens (human)Potency15.848910
2-[(2,5-dimethylphenyl)sulfonylamino]-N-[4-(2-pyrimidinylsulfamoyl)phenyl]benzamideHomo sapiens (human)Potency31.622810
3-methoxy-2-naphthalenecarboxylic acid [2-(4-morpholinyl)-2-oxoethyl] esterHomo sapiens (human)Potency25.118910
LSM-19724Homo sapiens (human)Potency25.118910
4-(diethylsulfamoyl)benzoic acid [2-[4-(6-methyl-1,3-benzothiazol-2-yl)anilino]-2-oxoethyl] esterHomo sapiens (human)Potency19.952610
4-amino-2-[[4-(1-azepanylsulfonyl)phenyl]-oxomethyl]isoindole-1,3-dioneHomo sapiens (human)Potency31.622810
1-butyl-2,4-dioxo-7-thiophen-2-yl-5-pyrido[2,3-d]pyrimidinecarboxylic acid ethyl esterHomo sapiens (human)Potency31.622810
6-amino-5-(butylamino)-1-propylpyrimidine-2,4-dioneHomo sapiens (human)Potency25.118910
4-(1H-benzimidazol-2-ylthio)butanoic acid [2-oxo-2-(4-phenoxyanilino)ethyl] esterHomo sapiens (human)Potency199.526010
N-(3-chloro-2-quinoxalinyl)-2-naphthalenesulfonamideHomo sapiens (human)Potency19.952610
2-(2-furanylmethylamino)benzoic acid [2-oxo-2-(3-oxo-2,4-dihydroquinoxalin-1-yl)ethyl] esterHomo sapiens (human)Potency25.118910
3-(2-chlorophenyl)sulfonylpropanoic acid [2-[(3,5-dichloro-6-methyl-2-pyridinyl)amino]-2-oxoethyl] esterHomo sapiens (human)Potency25.118910
1-(2-cyanoethyl)-6-(2-fluoro-4-methoxyphenyl)-3-methyl-4-pyrazolo[3,4-b]pyridinecarboxylic acid ethyl esterHomo sapiens (human)Potency31.622810
N2-[5-(4-chlorophenyl)-2-phenyl-3-pyrazolyl]benzene-1,2-diamineHomo sapiens (human)Potency199.526010
2-[(6-methyl-1H-benzimidazol-2-yl)thio]-1-(2-methyl-1H-indol-3-yl)ethanoneHomo sapiens (human)Potency89.125110
4-acetyl-N-[4-(4-chlorophenyl)-2-thiazolyl]-3,5-dimethyl-1H-pyrrole-2-carboxamideHomo sapiens (human)Potency79.432810
3-(benzenesulfonyl)propanoic acid [2-[(3,5-dichloro-4-methyl-2-pyridinyl)amino]-2-oxoethyl] esterHomo sapiens (human)Potency25.118910
4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)methyl]-7-ethyl-1-benzopyran-2-oneHomo sapiens (human)Potency31.622810
2-(butylamino)benzoic acid [2-oxo-2-(4-sulfamoylanilino)ethyl] esterHomo sapiens (human)Potency31.622810
5-(3,4-dimethoxyphenyl)-2-(1-piperidinyl)-7-thiazolo[4,5-b]pyridinecarboxylic acidHomo sapiens (human)Potency25.118910
2-[[2-[[5-(4-ethylanilino)-1,3,4-thiadiazol-2-yl]thio]-1-oxoethyl]amino]-3-thiophenecarboxamideHomo sapiens (human)Potency100.000010
N-[3-(4-morpholinyl)propyl]-3-(3-pyridinyl)-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amineHomo sapiens (human)Potency25.118910
4-chloro-N-[3-[(3,5-dimethyl-4-isoxazolyl)methylthio]-2-quinoxalinyl]benzenesulfonamideHomo sapiens (human)Potency15.848910
3-[ethyl(phenyl)sulfamoyl]-4-methylbenzoic acid (4-methyl-2-oxo-1-benzopyran-7-yl) esterHomo sapiens (human)Potency25.118910
2-(methylamino)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrileHomo sapiens (human)Potency12.589310
2-(1-piperidinyl)-6-thiophen-2-yl-4-(trifluoromethyl)-3-pyridinecarbonitrileHomo sapiens (human)Potency25.118910
6-(4-chlorophenyl)-4-(methylthio)-2-oxo-1H-pyridine-3-carbonitrileHomo sapiens (human)Potency31.622810
3-(4-methylphenyl)-2,1-benzoxazole-5-carboxaldehydeHomo sapiens (human)Potency25.118910
[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]hydrazineHomo sapiens (human)Potency31.622810
3-(dimethylaminomethylideneamino)-4-methoxy-2-thieno[2,3-b]pyridinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
4-(dimethylamino)-3-[(phenylmethoxyamino)methylideneamino]-2-thieno[2,3-b]pyridinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
2-chloro-N-(7-methyl-9-oxo-2-thioxanthenyl)benzamideHomo sapiens (human)Potency25.118910
1-[(3-chlorophenyl)methyl]-3-[5-(methylthio)-1,3,4-oxadiazol-2-yl]-2-pyridinoneHomo sapiens (human)Potency25.118910
4-chlorobenzoic acid [3-cyano-6-(3-methoxyphenyl)-2-pyridinyl] esterHomo sapiens (human)Potency25.118910
2-(benzenesulfonylmethyl)-5-(4-methoxyphenyl)cyclohexane-1,3-dioneHomo sapiens (human)Potency2.238710
5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-amineHomo sapiens (human)Potency25.118910
7-(3-hydroxyphenyl)-5-phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl esterHomo sapiens (human)Potency19.952610
3-chloro-1-(4-methoxyphenyl)-4-(3-methyl-1-piperidinyl)pyrrole-2,5-dioneHomo sapiens (human)Potency281.838010
8-methoxy-4-oxo-1H-quinoline-2-carboxylic acid methyl esterHomo sapiens (human)Potency25.118910
2-(3,5-dimethyl-1-pyrazolyl)benzonitrileHomo sapiens (human)Potency19.952610
Benzo[E]pyrazolo[5,1-c][1,2,4]triazin-8-yl N,N-dimethylcarbamateHomo sapiens (human)Potency25.118910
2-(4-morpholinyl)-5-[[oxo-[2-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]-3-furanyl]methyl]amino]benzoic acid methyl esterHomo sapiens (human)Potency89.125110
5-[[[5-(4-chlorophenyl)-2-(trifluoromethyl)-3-furanyl]-oxomethyl]amino]-2-(4-morpholinyl)benzoic acid methyl esterHomo sapiens (human)Potency89.125110
2-[[2-[[5-(4-tert-butylphenyl)-2-methoxycarbonyl-3-thiophenyl]amino]-2-oxoethyl]thio]acetic acidHomo sapiens (human)Potency25.118910
2-[4-(trifluoromethoxy)phenyl]imidazo[1,2-a]pyrimidineHomo sapiens (human)Potency12.589310
LSM-28486Homo sapiens (human)Potency25.118910
2-oxo-4,6-dithiophen-2-yl-1H-pyridine-3-carbonitrileHomo sapiens (human)Potency25.118910
3,3-dimethyl-1-[[9-(methylthio)-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]thio]-2-butanoneHomo sapiens (human)Potency31.622810
6-(2,3-dihydrobenzofuran-5-yl)-1H-pyrimidine-2-thioneHomo sapiens (human)Potency25.118910
2-[(Dimethylamino)methylidene]indan-1-oneHomo sapiens (human)Potency25.118910
2-[4-(2-methylpropyl)phenyl]propanoic acid [2-(1H-indol-3-yl)-2-oxoethyl] esterHomo sapiens (human)Potency89.125110
2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-phenylacetamideHomo sapiens (human)Potency25.118910
3-(4-ethyl-1-piperazinyl)-5-methylpyridazino[3,4-b][1,4]benzoxazineHomo sapiens (human)Potency25.118910
N,N'-diphenylcarbamimidothioic acid [1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl] esterHomo sapiens (human)Potency112.202010
4-[[4-(3-methylanilino)-3,5-dinitrophenyl]-oxomethyl]-1,3-dihydroquinoxalin-2-oneHomo sapiens (human)Potency125.892010
oreoseloneHomo sapiens (human)Potency25.118910
1-hexadecyl-3-methylimidazolium bromideHomo sapiens (human)Potency71.264210
N-[2-(4-chlorophenoxy)ethyl]-5-(3,5-dimethyl-1-piperazinyl)-2-nitroanilineHomo sapiens (human)Potency79.432810
N-[2-(4-methoxyphenoxy)ethyl]-5-(4-morpholinyl)-2-nitroanilineHomo sapiens (human)Potency89.125110
3-methyl-2-[(4-methylphenyl)sulfonylamino]pentanoic acid (4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-7-yl) esterHomo sapiens (human)Potency25.118910
4-methyl-2-[(4-methylphenyl)sulfonylamino]pentanoic acid (4-oxo-2,3-dihydro-1H-cyclopenta[c][1]benzopyran-7-yl) esterHomo sapiens (human)Potency25.118910
cid 2858522Homo sapiens (human)Potency70.794610
2,4-dichloro-6-[1-(4-morpholinyl)-3-phenylprop-2-ynyl]phenolHomo sapiens (human)Potency1,122.020010
4-[3-[[(2,5-dichloroanilino)-methyliminomethyl]thio]-2,5-dioxo-1-pyrrolidinyl]benzoic acid methyl esterHomo sapiens (human)Potency100.000010
N-(3-chloro-4-methylphenyl)-2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)acetamideHomo sapiens (human)Potency25.118910
N-[(2-hydroxy-1-naphthalenyl)-(4-methoxyphenyl)methyl]-2-methylpropanamideHomo sapiens (human)Potency31.622810
2-(2,4-dichlorophenyl)-3-(phenylmethyl)-1,2-dihydroquinazolin-4-oneHomo sapiens (human)Potency25.118910
3-acetamidobenzoic acid [2-(4-methylphenyl)-2-oxo-1-phenylethyl] esterHomo sapiens (human)Potency112.202010
1-cyclopentyl-2-imino-10-methyl-5-oxo-N-(2-oxolanylmethyl)-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
3-(2-furanylmethyl)-2-phenyl-1,2-dihydroquinazolin-4-oneHomo sapiens (human)Potency25.118910
5-(2-oxolanylmethylamino)-2-thiophen-2-yl-4-oxazolecarbonitrileHomo sapiens (human)Potency25.118910
N-[3-(4-chlorophenyl)-2-methyl-3H-1,5-benzodiazepin-4-yl]benzamideHomo sapiens (human)Potency70.794610
2-(2-oxo-1-benzo[cd]indolyl)-N-(2-oxolanylmethyl)acetamideHomo sapiens (human)Potency25.118910
importazoleHomo sapiens (human)Potency31.622810
2-[[(2-methoxy-4-nitroanilino)-sulfanylidenemethyl]amino]benzene-1,4-dicarboxylic acid diethyl esterHomo sapiens (human)Potency25.118910
2-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)thio]-N-(2-methoxy-3-dibenzofuranyl)acetamideHomo sapiens (human)Potency2,511.890010
1-[(4-tert-butylphenyl)methyl]-4-(4-nitrophenyl)imidazoleHomo sapiens (human)Potency89.125110
2-[4-(2-methyl-4-quinolinyl)-1-piperazinyl]-4-phenylthiazoleHomo sapiens (human)Potency562.341010
3-[5-(4-methylphenyl)-1-(2-oxolanylmethyl)-2-pyrrolyl]propanoic acidHomo sapiens (human)Potency31.622810
1-[2-furanyl(oxo)methyl]-6-(1-pyrrolidinylsulfonyl)-2-benzo[cd]indoloneHomo sapiens (human)Potency25.118910
3-[5-(4-methoxyphenyl)-1-(2-oxolanylmethyl)-2-pyrrolyl]propanoic acidHomo sapiens (human)Potency25.118910
3-[5-(4-fluorophenyl)-1-(2-oxolanylmethyl)-2-pyrrolyl]propanoic acidHomo sapiens (human)Potency25.118910
2-cyano-N-(phenylmethyl)-2-[3-(1-pyrrolidinyl)-2-quinoxalinyl]acetamideHomo sapiens (human)Potency31.622810
5,6-dihydro-4H-cyclopenta[b]thiophene-2-carboxylic acid [2-[(1,1-dioxo-3-thiolanyl)-(2-methylpropyl)amino]-2-oxoethyl] esterHomo sapiens (human)Potency31.622810
2-amino-4-chlorobenzoic acid [2-oxo-2-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethyl] esterHomo sapiens (human)Potency31.622810
2-(2-amino-4H-[1,3,5]triazino[2,1-b][1,3]benzoxazol-4-yl)propanedioic acid diethyl esterHomo sapiens (human)Potency25.118910
2-(2-furanyl)-N-(2-oxolanylmethyl)-4-quinolinecarboxamideHomo sapiens (human)Potency25.118910
3-(4-methylphenyl)sulfonyl-1-(3-oxolanylmethyl)-2-pyrrolo[3,2-b]quinoxalinamineHomo sapiens (human)Potency25.118910
2-chloro-n(6)-(3-iodobenzyl)adenosine-5'-n-methyluronamideHomo sapiens (human)Potency70.794610
acetic acid [6-ethyl-2-methyl-3-(1-methyl-2-benzimidazolyl)-4-oxo-1-benzopyran-7-yl] esterHomo sapiens (human)Potency15.848910
3-O-AcetylepisamarcandinHomo sapiens (human)Potency19.952610
2-[8-(6-amino-1H-benzimidazol-2-yl)octyl]-3H-benzimidazol-5-amineHomo sapiens (human)Potency794.328010
(3-bromophenyl)-[5-(4-bromophenyl)-3-ethyl-5-hydroxy-4H-pyrazol-1-yl]methanoneHomo sapiens (human)Potency89.125110
1-(4-bromophenyl)-N-(3,4-dichlorophenyl)-5-oxo-3-pyrrolidinecarboxamideHomo sapiens (human)Potency70.794610
3-(4-fluorophenyl)-5-(2-furanyl)-2-phenyl-3,4-dihydropyrazoleHomo sapiens (human)Potency25.118910
N-[3-[(4-chlorophenyl)-oxomethyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-3-pyridinecarboxamideHomo sapiens (human)Potency79.432810
7-(2-methoxyphenyl)-5-phenyl-1,7-dihydrotetrazolo[1,5-a]pyrimidineHomo sapiens (human)Potency19.952610
2-imino-1-[(4-methylphenyl)methyl]-5-oxo-N-(2-oxolanylmethyl)-3-dipyrido[1,2-d-3',4'-f]pyrimidinecarboxamideHomo sapiens (human)Potency31.622810
6-amino-5,7,7-tricyano-8-pyridin-4-yl-1,3,8,8a-tetrahydroisoquinoline-2-carboxylic acid (phenylmethyl) esterHomo sapiens (human)Potency25.118910
6-amino-2-ethyl-8-[2-(trifluoromethyl)phenyl]-1,6,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrileHomo sapiens (human)Potency25.118910
3-methyl-1-(3-propan-2-yloxypropylamino)-4-pyrido[1,2-a]benzimidazolecarbonitrileHomo sapiens (human)Potency25.118910
N-(2-methoxyethyl)-1-methyl-2-oxo-6-benzo[cd]indolesulfonamideHomo sapiens (human)Potency31.622810
LSM-24662Homo sapiens (human)Potency10.000010
2-(3-ethoxypropylamino)-8-methyl-5-oxo-N-(2-oxolanylmethyl)-3-dipyrido[1,2-pyrimidinecarboxamideHomo sapiens (human)Potency15.848910
1-[2-(dimethylamino)ethyl]-1-[(6-oxo-5H-[1,3]dioxolo[4,5-g]quinolin-7-yl)methyl]-3-(2-oxolanylmethyl)thioureaHomo sapiens (human)Potency25.118910
2-methoxy-4-[5-methyl-3-(2-oxolanylmethylamino)-2-imidazo[1,2-a]pyridinyl]phenolHomo sapiens (human)Potency25.118910
4-[3-(1,3-benzodioxol-5-ylmethylamino)-7-methyl-2-imidazo[1,2-a]pyridinyl]phenolHomo sapiens (human)Potency31.622810
4-amino-3-[(cyclohexylamino)-oxomethyl]-5-isothiazolecarboxylic acid [1-(cyclohexylamino)-1-oxopropan-2-yl] esterHomo sapiens (human)Potency25.118910
1-[2-[(3-cyano-5,7-dimethyl-2-quinolinyl)amino]ethyl]-3-(3-methoxypropyl)thioureaHomo sapiens (human)Potency25.118910
1-[3-[(7-cyano-[1,3]dioxolo[4,5-g]quinolin-6-yl)amino]propyl]-3-(3-methoxypropyl)thioureaHomo sapiens (human)Potency25.118910
1-[3-[(7-cyano-[1,3]dioxolo[4,5-g]quinolin-6-yl)amino]propyl]-3-(3-ethoxypropyl)thioureaHomo sapiens (human)Potency25.118910
1-[2-[(3-cyano-7-methyl-2-quinolinyl)amino]ethyl]-3-[3-(4-morpholinyl)propyl]thioureaHomo sapiens (human)Potency25.118910
N-[2-[(3-cyano-8-methyl-2-quinolinyl)amino]ethyl]benzenesulfonamideHomo sapiens (human)Potency31.622810
N-[2-(cyclopentylamino)-2-oxoethyl]-4,7-dimethyl-N-(2-methylphenyl)-2-oxo-3H-pyrido[1,2-a]pyrimidine-4-carboxamideHomo sapiens (human)Potency25.118910
[4-[5-tert-butyl-3-(phenylmethyl)-7-triazolo[4,5-d]pyrimidinyl]-1-piperazinyl]-(2-furanyl)methanoneHomo sapiens (human)Potency1,778.280010
N-[2-(3-fluorophenyl)-5-phenyl-7-pyrazolo[1,5-a]pyrimidinyl]-N',N'-dimethylpropane-1,3-diamineHomo sapiens (human)Potency25.118910
N-[4-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-5-methyl-2-thiazolyl]-2-(4-morpholinyl)acetamideHomo sapiens (human)Potency354.813010
3-[2-[butyl(methyl)amino]ethyl]-6-(4-morpholinyl)-2-sulfanylidene-1H-quinazolin-4-oneHomo sapiens (human)Potency25.118910
N-(2,4-dimethoxyphenyl)-3-[[2-(2-methoxyphenoxy)-1-oxoethyl]amino]-2-benzofurancarboxamideHomo sapiens (human)Potency25.118910
7-(4-methoxyphenyl)-5-methyl-2-(methylthio)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidineHomo sapiens (human)Potency25.118910
2-(3-oxo-2,4-dihydro-1H-quinoxalin-2-yl)-N-(1-phenylethyl)acetamideHomo sapiens (human)Potency25.118910
2-phenyl-5-(1-piperidinyl)-4-triazolecarbonitrileHomo sapiens (human)Potency25.118910
2,4-dioxo-3-pentyl-N-[3-(1-piperidinyl)propyl]-1H-quinazoline-7-carboxamideHomo sapiens (human)Potency25.118910
1-oxo-N-(3-pyridinyl)-2-benzopyran-4-carboxamideHomo sapiens (human)Potency25.118910
4-[2-[(1'-acetyl-4-oxo-6-spiro[3,4-dihydro-2H-1-benzopyran-2,4'-piperidine]yl)oxy]-1-oxoethyl]-1-piperazinecarboxylic acid ethyl esterHomo sapiens (human)Potency31.622810
2-[(3-oxo-2-propan-2-yl-2H-imidazo[1,2-c]quinazolin-5-yl)thio]-N-[2-(4-sulfamoylphenyl)ethyl]acetamideHomo sapiens (human)Potency25.118910
N-[2-(1-tert-butyl-3,4,6-trimethyl-5-pyrazolo[3,4-b]pyridinyl)ethyl]carbamic acid ethyl esterHomo sapiens (human)Potency112.202010
5-bromo-N-[2-(2-chlorophenyl)-1,3-benzoxazol-5-yl]-3-pyridinecarboxamideHomo sapiens (human)Potency19.952610
9-(4-methoxyphenyl)-3,3,6,6-tetramethyl-10-[2-(4-morpholinyl)ethyl]-4,5,7,9-tetrahydro-2H-acridine-1,8-dioneHomo sapiens (human)Potency25.118910
5a,6,7,8,9,10-hexahydro-5H-azepino[2,1-b]quinazolin-12-oneHomo sapiens (human)Potency25.118910
N-(3-chlorophenyl)-5-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)-3-methyl-2-benzofurancarboxamideHomo sapiens (human)Potency44.668410
N-(1,3-benzodioxol-5-ylmethyl)-3-cyclopentyl-2,4-dioxo-1H-quinazoline-7-carboxamideHomo sapiens (human)Potency31.622810
N-(5-chloro-2,4-dimethoxyphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamideHomo sapiens (human)Potency35.481310
2,4-dioxo-3-(2-oxolanylmethyl)-N-pentyl-1H-quinazoline-7-carboxamideHomo sapiens (human)Potency25.118910
N-[4-methyl-2-(4-methyl-1-piperazinyl)-6-quinolinyl]-1,3-benzodioxole-5-carboxamideHomo sapiens (human)Potency31.622810
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanoneHomo sapiens (human)Potency25.118910
2-chloro-6-[4-morpholinyl(oxo)methyl]-11-pyrido[2,1-b]quinazolinoneHomo sapiens (human)Potency25.118910
N-(2-furanylmethyl)-N'-[4-methyl-2-(4-methyl-1-piperazinyl)-6-quinolinyl]butanediamideHomo sapiens (human)Potency25.118910
3-[5-(4-fluorophenyl)-7-phenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]-1-propanolHomo sapiens (human)Potency31.622810
1-[(6-methoxy-2-furo[2,3-b]quinolinyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
N-(2-furanylmethyl)-1-[2-(2-hydroxyethoxy)ethyl]-2-imino-10-methyl-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
2-(2-ethoxyphenyl)-8-oxo-9-phenyl-7H-purine-6-carboxamideHomo sapiens (human)Potency3.981110
6-methoxy-N-(thiophen-2-ylmethyl)-2-furo[2,3-b]quinolinecarboxamideHomo sapiens (human)Potency15.848910
N-[2-(3,4-diethoxyphenyl)ethyl]-1-[6-(4-morpholinyl)-3-pyridazinyl]-4-piperidinecarboxamideHomo sapiens (human)Potency25.118910
5-(1-ethyl-3-methyl-4-pyrazolyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxylic acidHomo sapiens (human)Potency25.118910
LSM-28187Homo sapiens (human)Potency31.622810
2,6-dimethyl-4-(4-phenyl-2-quinolinyl)morpholineHomo sapiens (human)Potency25.118910
3-[3-(N-ethylanilino)propyl]-6-(4-morpholinyl)-2-sulfanylidene-1H-quinazolin-4-oneHomo sapiens (human)Potency19.952610
2-(1-benzo[e]benzofuranyl)-N-[4-methoxy-3-(4-morpholinylsulfonyl)phenyl]acetamideHomo sapiens (human)Potency14.125410
1-(3-ethoxypropyl)-2-[2-furanyl(oxo)methyl]imino-10-methyl-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
LSM-20806Homo sapiens (human)Potency25.118910
2-[(4-cyano-1-oxo-5H-pyrido[1,2-a]benzimidazol-3-yl)methylthio]propanoic acidHomo sapiens (human)Potency25.118910
N-[4-[2-(2-ethyl-1-oxobutyl)-3-phenyl-3,4-dihydropyrazol-5-yl]phenyl]methanesulfonamideHomo sapiens (human)Potency31.622810
N-[2-(4-morpholinyl)ethyl]-2-(4-propan-2-yloxyphenyl)-4-quinolinecarboxamideHomo sapiens (human)Potency25.118910
2-[[2-(4-methoxyphenyl)-6-methyl-1-benzopyran-4-ylidene]amino]-4-methylpentanoic acidHomo sapiens (human)Potency31.622810
1-butyl-2-[2-furanyl(oxo)methyl]imino-10-methyl-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
7-methoxy-2-(3-methoxyanilino)-3-quinolinecarbonitrileHomo sapiens (human)Potency31.622810
N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]-2-[4-methyl-4-(4-methylphenyl)-2,5-dioxo-1-imidazolidinyl]acetamideHomo sapiens (human)Potency25.118910
ro 41-0960Homo sapiens (human)Potency707.946010
6-[2-butylimino-3-(cyclopentylideneamino)-4-thiazolyl]-4H-1,4-benzoxazin-3-oneHomo sapiens (human)Potency89.125110
2-benzoylimino-1-(2-furanylmethyl)-10-methyl-5-oxo-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxylic acid ethyl esterHomo sapiens (human)Potency22.028910
N4-(2-furanylmethyl)-N2-(3-methoxyphenyl)-5-nitropyrimidine-2,4,6-triamineHomo sapiens (human)Potency79.432810
8-methylene-7-(phenylmethyl)-5H-[1,3]dioxolo[4,5-g]quinazoline-6-thioneHomo sapiens (human)Potency12.589310
2-chloro-8-[4-morpholinyl(oxo)methyl]-11-pyrido[2,1-b]quinazolinoneHomo sapiens (human)Potency25.118910
N-(6-acetamido-3-prop-2-enyl-1,3-benzothiazol-2-ylidene)-2-thiophenecarboxamideHomo sapiens (human)Potency19.952610
2-[2-[(5-chloro-2-thiophenyl)-oxomethyl]imino-6-fluoro-1,3-benzothiazol-3-yl]acetic acid methyl esterHomo sapiens (human)Potency25.118910
4-[4-dimethoxyphosphoryl-2-(1-naphthalenyl)-5-oxazolyl]morpholineHomo sapiens (human)Potency25.118910
obtusininHomo sapiens (human)Potency25.118910
2-[4-methoxy-3-(4-morpholinylmethyl)phenyl]-3-(phenylmethyl)-1,2-dihydroquinazolin-4-oneHomo sapiens (human)Potency25.118910
7-(5-bromo-2-fluorophenyl)-5-(4-bromophenyl)-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidineHomo sapiens (human)Potency25.118910
6-[2-(1-azepanyl)-2-oxoethoxy]-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-oneHomo sapiens (human)Potency25.118910
1-[(2,6-dichlorophenyl)methyl]-5-(4-methylphenyl)-2-oxo-3-pyridinecarbonitrileHomo sapiens (human)Potency15.848910
2-thiophen-2-yl-4-quinolinecarboxylic acid (2-oxo-3-oxolanyl) esterHomo sapiens (human)Potency25.118910
5-(4-ethoxyphenyl)-1,3-diphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dioneHomo sapiens (human)Potency25.118910
2-(1,3-benzothiazol-2-ylthio)-N-[2-hydroxy-5-(4-morpholinylsulfonyl)phenyl]acetamideHomo sapiens (human)Potency50.118710
N-[3-[(3-chlorophenyl)sulfamoyl]-4-methylphenyl]-3-(4-nitrophenyl)-3-oxopropanamideHomo sapiens (human)Potency158.489010
2-[(2,2-dimethyl-4-oxo-3,4-dihydro-2H-1-benzopyran-6-yl)oxy]-N-heptylacetamideHomo sapiens (human)Potency31.622810
2-[(4-amino-7-tert-butyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)thio]acetic acidHomo sapiens (human)Potency25.118910
10-[3-(dibutylamino)-2-hydroxypropyl]-9-acridinoneHomo sapiens (human)Potency25.118910
2-(4-ethoxyphenyl)-N-[3-(1-imidazolyl)propyl]-4-quinolinecarboxamideHomo sapiens (human)Potency25.118910
2-(4-chlorophenyl)-5-methyl-4-oxo-2,3-dihydro-1H-thieno[3,4-d]pyrimidine-7-carboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
2-[(3-ethyl-7-methyl-4-oxo-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-2-yl)thio]-N-(2-phenylethyl)acetamideHomo sapiens (human)Potency19.952610
4-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitrobenzoic acid methyl esterHomo sapiens (human)Potency158.489010
2-[4-[3-(4-methoxyphenyl)-1H-pyrazol-5-yl]-1-piperidinyl]-3-nitropyridineHomo sapiens (human)Potency89.125110
2-[[2-(3,4-dimethoxyphenyl)-6-methyl-1-benzopyran-4-ylidene]amino]butanoic acidHomo sapiens (human)Potency25.118910
LSM-17147Homo sapiens (human)Potency15.848910
1-amino-N-methyl-5-(4-morpholinyl)-N-phenyl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxamideHomo sapiens (human)Potency31.622810
AnthraniloyllycoctonineHomo sapiens (human)Potency25.118910
3,5-diethyl-2-(3-hydroxypropylamino)-5-methyl-6H-benzo[h]quinazolin-4-oneHomo sapiens (human)Potency31.622810
LSM-31277Homo sapiens (human)Potency31.622810
2-amino-4-(2-fluorophenyl)-6-(3-pyridinyl)-3-pyridinecarbonitrileHomo sapiens (human)Potency25.118910
4-[(3-cyano-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)thio]-3-oxobutanoic acid ethyl esterHomo sapiens (human)Potency31.622810
2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrileHomo sapiens (human)Potency25.118910
3-(2-methoxyphenyl)-2-methyl-4-oxo-1H-quinazoline-2-carboxylic acid methyl esterHomo sapiens (human)Potency25.118910
N-[6-amino-2,4-dioxo-1-(phenylmethyl)-5-pyrimidinyl]-N-ethyl-2-(2-methyl-2,3-dihydroindol-1-yl)acetamideHomo sapiens (human)Potency15.848910
1-[2-(3,4-dimethoxyphenyl)ethyl]-2-imino-10-methyl-5-oxo-N-(2-oxolanylmethyl)-3-dipyrido[3,4-c-1',2'-f]pyrimidinecarboxamideHomo sapiens (human)Potency25.118910
3-(2-chlorophenyl)-N-[5-(2,4-dichlorophenyl)-1,3,4-thiadiazol-2-yl]-5-methyl-4-isoxazolecarboxamideHomo sapiens (human)Potency25.118910
N-[3-[3-(1-piperidinylsulfonyl)anilino]-2-quinoxalinyl]benzenesulfonamideHomo sapiens (human)Potency25.118910
6-(4-morpholinyl)-3-(2-phenylethyl)-2-sulfanylidene-1H-quinazolin-4-oneHomo sapiens (human)Potency31.622810
N-(1,3-benzodioxol-5-ylmethyl)-6-[6-(4-morpholinyl)-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl]hexanamideHomo sapiens (human)Potency19.952610
N-[4-oxo-2-(2-pyridinyl)-1,2-dihydroquinazolin-3-yl]acetamideHomo sapiens (human)Potency25.118910
3-(2-fluorophenyl)-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxylic acid methyl esterHomo sapiens (human)Potency25.118910
2-(5-bromo-2-thiophenyl)-N-(4-methyl-1-piperazinyl)-4-quinolinecarboxamideHomo sapiens (human)Potency25.118910
7-methoxy-N-(3-pyridinylmethyl)-2-furo[2,3-b]quinolinecarboxamideHomo sapiens (human)Potency25.118910
3-(4-fluorophenyl)sulfonyl-1-(2-furanylmethyl)-2-imino-10-methyl-5-dipyrido[3,4-c-1',2'-f]pyrimidinoneHomo sapiens (human)Potency3.162310
LSM-19765Homo sapiens (human)Potency6.309610
2,6-dichloro-1,7-dimethylpyrazolo[1,2-a]pyrazole-3,5-dioneHomo sapiens (human)Potency25.118910
2-(2-bromophenyl)-3-[3-(4-morpholinyl)propyl]-1,2-dihydroquinazolin-4-oneHomo sapiens (human)Potency25.118910
2-(2-furanylmethylamino)benzoic acid [2-[(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)amino]-2-oxoethyl] esterHomo sapiens (human)Potency10.000010
N-[4-(1H-benzimidazol-2-yl)phenyl]-3-(2,5-dioxo-1-pyrrolidinyl)benzamideHomo sapiens (human)Potency31.622810
LSM-22688Homo sapiens (human)Potency398.107010
N-[3-[(2,4-dimethylphenyl)sulfamoyl]-4-methylphenyl]-3-oxo-4H-1,4-benzothiazine-6-carboxamideHomo sapiens (human)Potency125.892010
6-(2,3-dihydro-1,4-benzodioxin-3-yl)-3-(phenoxymethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoleHomo sapiens (human)Potency44.668410
N-(3-chlorophenyl)-2-[4-oxo-2-phenylimino-3-(2-pyridinylmethyl)-5-thiazolidinyl]acetamideHomo sapiens (human)Potency79.432810
2-[4-(2,5-diphenyl-3,4-dihydropyrazol-3-yl)-2-methoxyphenoxy]acetic acidHomo sapiens (human)Potency25.118910
isovitexinHomo sapiens (human)Potency25.118910
4-(9-acridinylamino)-1,5-dimethyl-2-phenyl-3-pyrazoloneHomo sapiens (human)Potency31.622810
N-[3-[(2-bromo-5-methylphenyl)sulfamoyl]-4-methoxyphenyl]-4-fluorobenzamideHomo sapiens (human)Potency125.892010
4-[7-(2-methoxyethyl)-2,6-dioxo-3-(phenylmethyl)-8-purinyl]benzonitrileHomo sapiens (human)Potency25.118910
3-amino-4-[(4-chlorophenyl)thio]benzoic acid methyl esterHomo sapiens (human)Potency25.118910
LSM-31434Homo sapiens (human)Potency31.622810
2-bromo-6-[1,4-dioxa-8-azaspiro[4.5]decan-8-yl(oxo)methyl]-11-pyrido[2,1-b]quinazolinoneHomo sapiens (human)Potency25.118910
2-[[(3,4-dimethoxyphenyl)-oxomethyl]amino]acetic acid [2-[5-(4-chlorophenyl)-3-(2-furanyl)-3,4-dihydropyrazol-2-yl]-2-oxoethyl] esterHomo sapiens (human)Potency251.189010
2-(3-methoxyphenyl)-3,5,6,7,8,9-hexahydrocyclohepta[2,3]thieno[2,4-b]pyrimidin-4-oneHomo sapiens (human)Potency12.589310
N-(5-methyl-3-isoxazolyl)-2-(4-propan-2-yloxyphenyl)-4-quinolinecarboxamideHomo sapiens (human)Potency25.118910
4-dimethoxyphosphoryl-2-(1-naphthalenyl)-N-(phenylmethyl)-5-oxazolamineHomo sapiens (human)Potency31.622810
2-[4-chloro-2-[3-(4-methoxyphenyl)-4-oxo-1,2-dihydroquinazolin-2-yl]phenoxy]acetic acid methyl esterHomo sapiens (human)Potency25.118910
N-[4-(4-fluorophenyl)-2-thiazolyl]-3-methoxy-4-[2-(4-morpholinyl)-2-oxoethoxy]benzamideHomo sapiens (human)Potency89.125110
4-[[[1-oxo-2-[(2-oxo-3-phenyl-1-benzopyran-7-yl)oxy]propyl]amino]methyl]-1-cyclohexanecarboxylic acidHomo sapiens (human)Potency25.118910
N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]benzamideHomo sapiens (human)Potency199.526010
2-methyl-1-cyclopropanecarboxylic acid [5-[2-(3,4-dimethoxyphenyl)-4-quinolinyl]-1,3,4-oxadiazol-2-yl]methyl esterHomo sapiens (human)Potency19.952610
5'-bromo-2'-spiro[1,2-dihydro-4,1,2-benzoxadiazine-3,3'-1H-indole]oneHomo sapiens (human)Potency79.432810
3-(1-methyl-2-benzimidazolyl)-1-(3-methylphenyl)-2-pyrrolo[3,2-b]quinoxalinamineHomo sapiens (human)Potency19.952610
5-(4-methylphenyl)-2-(1-piperidinyl)-7-thiazolo[4,5-b]pyridinecarboxylic acidHomo sapiens (human)Potency25.118910
3-[(4-methyl-1-piperazinyl)sulfonyl]-N-(4-phenyl-2-thiazolyl)-N-prop-2-enylbenzamideHomo sapiens (human)Potency89.125110
N-[2-(4-methoxyphenyl)-4-oxo-1,2-dihydroquinazolin-3-yl]carbamic acid ethyl esterHomo sapiens (human)Potency25.118910
N-(3-oxo-2-benzo[f][1]benzopyranyl)acetamideHomo sapiens (human)Potency15.848910
[5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-3-pyrazolyl]-(4-morpholinyl)methanoneHomo sapiens (human)Potency89.125110
3-(5,7-diphenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-1-propanolHomo sapiens (human)Potency25.118910
2-[[3-butyl-6-(4-morpholinyl)-4-oxo-2-quinazolinyl]thio]acetamideHomo sapiens (human)Potency25.118910
5,6-dimethyl-1-octyl-4-benzimidazolamineHomo sapiens (human)Potency89.125110
2-[3-(1-benzotriazolylmethyl)-4-methoxyphenyl]-3-(4-methoxyphenyl)-1,2-dihydroquinazolin-4-oneHomo sapiens (human)Potency25.118910
sphingosineHomo sapiens (human)Potency70.794610
genisteinHomo sapiens (human)Potency562.341010
amentoflavoneHomo sapiens (human)Potency89.125110
7-hydroxy-6,4'-dimethoxyisoflavoneHomo sapiens (human)Potency25.118910
coumestrolHomo sapiens (human)Potency31.622810
trans-2,3',4,5'-tetrahydroxystilbeneHomo sapiens (human)Potency25.118910
fenretinideHomo sapiens (human)Potency100.000010
8-(1-piperidinylsulfonyl)-6-pyrido[1,2-a]quinazolinoneHomo sapiens (human)Potency31.622810
1,5-dimethyl-4-oxo-N-[2-(3-thiophenyl)ethyl]-2-pyrrolo[3,2-c]quinolinecarboxamideHomo sapiens (human)Potency354.813010
N-(2-furanylmethyl)-3-(2,4,8,10-tetramethyl-3-pyrido[2,3]pyrazolo[2,4-a]pyrimidinyl)propanamideHomo sapiens (human)Potency25.118910
N-(6-acetyl-1,3-benzodioxol-5-yl)-5-methyl-2-phenyl-3-pyrazolecarboxamideHomo sapiens (human)Potency31.622810
4-methyl-2,3-dihydro-1,4-benzothiazine-6-carboxylic acid methyl esterHomo sapiens (human)Potency25.118910
N-[2-(4-morpholinyl)ethyl]-4-(phenylmethyl)-2,3-dihydro-1,4-benzothiazine-6-carboxamideHomo sapiens (human)Potency25.118910
N-[3-(4-methyl-1-piperazinyl)propyl]-4-(phenylmethyl)-2,3-dihydro-1,4-benzothiazine-6-carboxamideHomo sapiens (human)Potency25.118910
2-(2-chlorophenyl)-9-(3-methylphenyl)-8-oxo-7H-purine-6-carboxamideHomo sapiens (human)Potency25.118910
N-cycloheptyl-3-(2-methoxyethyl)-2,4-dioxo-1H-quinazoline-7-carboxamideHomo sapiens (human)Potency25.118910
8-(diethylaminomethyl)-7-hydroxy-4-phenyl-1-benzopyran-2-oneHomo sapiens (human)Potency25.118910
3-[6-[4-(trifluoromethoxy)anilino]-4-pyrimidinyl]benzamideHomo sapiens (human)Potency112.202010
su 6656Homo sapiens (human)Potency89.125110
bornyl ferulateHomo sapiens (human)Potency25.118910
cycloheterophyllinHomo sapiens (human)Potency398.107010
neoglycyrolHomo sapiens (human)Potency25.118910
thunberginol aHomo sapiens (human)Potency25.118910
4-[(3aR,4S,9bS)-8-[(4-methoxyphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acidHomo sapiens (human)Potency100.000010
4-methyl-2,7-diphenyl-8H-pyrido[2,3-d]pyrimidin-5-oneHomo sapiens (human)Potency25.118910
8-[[butyl(ethyl)amino]methyl]-7-hydroxy-4-phenyl-1-benzopyran-2-oneHomo sapiens (human)Potency25.118910
5,7-dihydroxy-4-methylcoumarinHomo sapiens (human)Potency25.118910
4-amino-6,7-diphenyl-3H-pteridine-2-thioneHomo sapiens (human)Potency10.000010
7-hydroxy-4-phenyl-8-(1-piperidinylmethyl)-1-benzopyran-2-oneHomo sapiens (human)Potency15.848910
isoalloxazineHomo sapiens (human)Potency31.622810
7-hydroxy-4-methyl-1H-quinolin-2-oneHomo sapiens (human)Potency19.952610
5-deazaflavinHomo sapiens (human)Potency25.118910
7-hydroxyisoflavoneHomo sapiens (human)Potency25.118910
2-(4-(dimethylamino)styryl)benzothiazoleHomo sapiens (human)Potency25.118910
7-Hydroxy-2-methylisoflavoneHomo sapiens (human)Potency25.118910
2-(5,7-dihydroxy-4-methyl-2-oxo-1-benzopyran-3-yl)acetic acid ethyl esterHomo sapiens (human)Potency25.118910
3-(1-benzimidazolyl)-6-ethyl-7-hydroxy-1-benzopyran-4-oneHomo sapiens (human)Potency25.118910
10H-phenanthro[9,10-g]pteridine-11,13-dioneHomo sapiens (human)Potency15.848910
3-bromo-7-hydroxy-4,8-dimethyl-1-benzopyran-2-oneHomo sapiens (human)Potency25.118910
5,7-dihydroxy-4-methyl-3-(phenylmethyl)-1-benzopyran-2-oneHomo sapiens (human)Potency31.622810
baohuoside iiHomo sapiens (human)Potency89.125110
8-(diethylaminomethyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-hydroxy-1-benzopyran-4-oneHomo sapiens (human)Potency25.118910
7-hydroxy-8-methyl-4-[[methyl-(phenylmethyl)amino]methyl]-1-benzopyran-2-oneHomo sapiens (human)Potency25.118910
3-(dimethylamino)benzoic acid (7-hydroxy-2-oxo-1-benzopyran-4-yl)methyl esterHomo sapiens (human)Potency25.118910
methylbenzethonium chlorideHomo sapiens (human)Potency63.095710
CrotaoprostrinHomo sapiens (human)Potency316.228010
3,8-dibromo-7-hydroxy-4-methylchromen-2-oneHomo sapiens (human)Potency25.118910
DPI2Homo sapiens (human)Potency794.328010
alpha-(p-Methoxyphenyl)-2-pyridineacrylonitrileHomo sapiens (human)Potency25.118910
Adenosine 5'-monophosphate monohydrateHomo sapiens (human)Potency44.668410
dihydroergotoxineHomo sapiens (human)Potency19.952610
marminHomo sapiens (human)Potency25.118910
LSM-18452Homo sapiens (human)Potency15.848910
[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-[(3R)-2,3-dihydro-1,4-benzodioxin-3-yl]methanoneHomo sapiens (human)Potency25.118910
2-methyl-5-[(2-oxo-1H-benzo[cd]indol-6-yl)sulfonylamino]-3-benzofurancarboxylic acid butyl esterHomo sapiens (human)Potency125.892010
[4-(phenylmethyl)-2,3-dihydro-1,4-benzothiazin-6-yl]-(1-piperidinyl)methanoneHomo sapiens (human)Potency31.622810
2-(2-furanyl)-N-phenyl-3-imidazo[1,2-a]pyridinamineHomo sapiens (human)Potency15.848910
1-(4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-N-(phenylmethyl)-3-piperidinecarboxamideHomo sapiens (human)Potency31.622810
5-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-3-methyl-2-thiophenecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
3-[(2S,4S)-2-(4-hydroxybutoxy)-6-[4-morpholinyl(oxo)methyl]-3,4-dihydro-2H-pyran-4-yl]-1-benzopyran-4-oneHomo sapiens (human)Potency31.622810
LSM-6455Homo sapiens (human)Potency31.622810
2-[4-(2-pyrimidinyl)-1-piperazinyl]quinolineHomo sapiens (human)Potency19.952610
4-fluoro-N-(4-fluoro-1,3-benzothiazol-2-yl)-1,3-benzothiazol-2-amineHomo sapiens (human)Potency25.118910
N-(6-fluoro-1,3-benzothiazol-2-yl)-6,7-dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-amineHomo sapiens (human)Potency19.952610
2-[4-ethoxy-2-[2-furanyl(oxo)methyl]imino-1,3-benzothiazol-3-yl]acetic acid methyl esterHomo sapiens (human)Potency25.118910
3-butyl-10-phenylpyrimido[4,5-b]quinoline-2,4-dioneHomo sapiens (human)Potency25.118910
2-(3,5-dimethyl-1H-pyrrol-2-yl)-1,3-benzothiazoleHomo sapiens (human)Potency12.589310
2-amino-3-methyl-7-(2-phenylethyl)-5H-pteridine-4,6-dioneHomo sapiens (human)Potency25.118910
N-[2-(3-methoxyphenyl)-4-[(4-methoxyphenyl)methoxy]-6-quinolinyl]-3-pyridinecarboxamideHomo sapiens (human)Potency79.432810
4-[[[4-[(4-fluorophenyl)methyl]-2,3-dihydro-1,4-benzothiazin-6-yl]-oxomethyl]amino]-1-piperidinecarboxylic acid ethyl esterHomo sapiens (human)Potency25.118910
N-[3-(4-morpholinyl)propyl]-2,4-dioxo-3-(2-phenylethyl)-1H-quinazoline-7-carboxamideHomo sapiens (human)Potency25.118910
5-chloro-N-[4-(2-thiazolo[5,4-b]pyridinyl)phenyl]-2-thiophenesulfonamideHomo sapiens (human)Potency25.118910
4-[[oxo-[4-(phenylmethyl)-2,3-dihydro-1,4-benzothiazin-6-yl]methyl]amino]-1-piperidinecarboxylic acid ethyl esterHomo sapiens (human)Potency31.622810
N-(6-methoxy-1,3-benzothiazol-2-yl)-1-thiophen-2-ylsulfonyl-4-piperidinecarboxamideHomo sapiens (human)Potency223.872010
1'-acetyl-6-[2-(4-ethyl-1-piperazinyl)-2-oxoethoxy]-4-spiro[3,4-dihydro-2H-1-benzopyran-2,4'-piperidine]oneHomo sapiens (human)Potency25.118910
3-(2-methoxyethyl)-2,4-dioxo-N-pentyl-1H-quinazoline-7-carboxamideHomo sapiens (human)Potency25.118910
chlorhexidineHomo sapiens (human)Potency89.125110
cgp 20712aHomo sapiens (human)Potency25.118910
levodopa methyl ester hydrochlorideHomo sapiens (human)Potency39.810710
R-(-)-actinodaphnineHomo sapiens (human)Potency39.810710
calcimycinHomo sapiens (human)Potency25.118910
apocodeine hydrochloride, (r)-isomerHomo sapiens (human)Potency15.848910
N-[5-[2-(4-chloroanilino)-4-thiazolyl]-4-methyl-2-thiazolyl]-2-furancarboxamideHomo sapiens (human)Potency891.251010
N-[(2-methoxyphenyl)methyl]-2-methyl-3-prop-2-enoxy-6-indazolecarboxamideHomo sapiens (human)Potency25.118910
3-hydroxy-3-methyl-5-oxo-5-[[3,4,5-trihydroxy-6-[[6-methoxy-2-oxo-3-[(2-oxo-1-benzopyran-7-yl)oxy]-1-benzopyran-7-yl]oxy]-2-oxanyl]methoxy]pentanoic acidHomo sapiens (human)Potency25.118910
1-(4-bromophenyl)-3-[[[4-(4-morpholinyl)-3-nitrophenyl]-oxomethyl]amino]thioureaHomo sapiens (human)Potency112.202010
N-(3-fluorophenyl)-2-(9-oxo-10-acridinyl)acetamideHomo sapiens (human)Potency7.943310
4-[3-(2-furanyl)-4-(3-nitrophenyl)-6-oxo-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid ethyl esterHomo sapiens (human)Potency28.183810
3-(benzenesulfonyl)-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]propanamideHomo sapiens (human)Potency25.118910
[9-(benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanoneHomo sapiens (human)Potency25.118910
Moracin PHomo sapiens (human)Potency630.957010
win 62577Homo sapiens (human)Potency25.118910
foetidinHomo sapiens (human)Potency1,778.280010
3-[(4-methoxyphenyl)methyl]-N-(3-methoxypropyl)-2,4-dioxo-1H-quinazoline-7-carboxamideHomo sapiens (human)Potency31.622810
N'-butan-2-yl-N-[2-(3,5-dimethyl-1-piperidinyl)-4-methyl-6-quinolinyl]butanediamideHomo sapiens (human)Potency25.118910
2-(5,8-dimethyl-2,4-dioxo-3-phenyl-1-pyrimido[5,4-b]indolyl)-N-(2-oxolanylmethyl)acetamideHomo sapiens (human)Potency25.118910
8-methyl-4-oxo-N-[3-(4-propyl-1-piperazinyl)propyl]-5H-thieno[3,2-c]quinoline-2-carboxamideHomo sapiens (human)Potency31.622810
[1-[(1,2-dimethyl-3-indolyl)methyl]-4-[[3-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methanolHomo sapiens (human)Potency630.957010
5-[[1-(2-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]methyl]-2-methylthiazoleHomo sapiens (human)Potency25.118910
1-butyl-3-[2-(4-ethyl-1-piperazinyl)-4-methyl-6-quinolinyl]-1-methylthioureaHomo sapiens (human)Potency15.848910
N-[3-(1-azepanyl)propyl]-3-[(4-methoxyphenyl)methyl]-2,4-dioxo-1H-quinazoline-7-carboxamideHomo sapiens (human)Potency25.118910
2-[[6-(4-morpholinyl)-4-oxo-3-(2-phenylethyl)-2-quinazolinyl]thio]-N-(2-oxolanylmethyl)acetamideHomo sapiens (human)Potency25.118910
3-phenylpropanoic acid [3-(4-cyanophenyl)-7-methyl-6,8-dioxo-2-[2-(2-pyridinyl)ethyl]-7-isoquinolinyl] esterHomo sapiens (human)Potency25.118910
3-(4-methylphenyl)-5-oxo-N-propyl-8-thiazolo[2,3-b]quinazolinecarboxamideHomo sapiens (human)Potency25.118910
3-(4-methylphenyl)-5-oxo-8-thiazolo[2,3-b]quinazolinecarboxamideHomo sapiens (human)Potency25.118910
reserpic acid, hydrochloride salt, (3beta,16beta,17alpha,18beta,20alpha)-isomerHomo sapiens (human)Potency31.622810
N-[2-(2,5-dimethoxyphenyl)ethyl]-4-[(4-fluorophenyl)methyl]-2,3-dihydro-1,4-benzothiazine-6-carboxamideHomo sapiens (human)Potency25.118910
N-[(5-bromo-2-methoxyphenyl)methyl]-4-methyl-2,3-dihydro-1,4-benzothiazine-6-carboxamideHomo sapiens (human)Potency25.118910
4-[4-(4-fluorophenyl)-1-piperazinyl]-N-[4-methyl-2-(4-morpholinyl)-6-quinolinyl]-4-oxobutanamideHomo sapiens (human)Potency31.622810
montelukast sodiumHomo sapiens (human)Potency19.952610
cefamandole nafateHomo sapiens (human)Potency70.794610
1-butyl-2-(2-methylphenyl)-7-propan-2-yl-5H-imidazo[4,5-g]quinoxalin-6-oneHomo sapiens (human)Potency31.622810
4-(4-acetyloxyphenyl)benzoic acid [2-[[2-(2-chloroanilino)-2-oxoethyl]-methylamino]-2-oxoethyl] esterHomo sapiens (human)Potency112.202010
LSM-1287Homo sapiens (human)Potency79.432810
LSM-1315Homo sapiens (human)Potency112.202010
3-[(2-fluorophenyl)methyl]-5-methyl-4-thieno[3,4]pyrrolo[1,3-d]pyrimidinoneHomo sapiens (human)Potency25.118910
N-(1,3-benzodioxol-5-ylmethyl)-6-(2-chlorophenyl)-4-quinazolinamineHomo sapiens (human)Potency70.794610
6-(2-chlorophenyl)-N-[(4-methyl-2-thiophenyl)methyl]-4-quinazolinamineHomo sapiens (human)Potency79.432810
N-[4-cyano-2-(1-naphthalenyl)-5-oxazolyl]acetamideHomo sapiens (human)Potency25.118910
5-amino-2-(1-naphthalenyl)-4-oxazolecarbonitrileHomo sapiens (human)Potency31.622810
4-[5-(3-hydroxy-4-oxo-1,2-dihydroquinazolin-2-yl)-2-furanyl]benzonitrileHomo sapiens (human)Potency31.622810
3-hydroxy-2-(5-thiophen-2-yl-2-furanyl)-1,2-dihydroquinazolin-4-oneHomo sapiens (human)Potency19.952610
1-[[(2S,3R)-10-[[(cyclohexylamino)-oxomethyl]amino]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methyl-3-[4-(trifluoromethyl)phenyl]ureaHomo sapiens (human)Potency100.000010
1-[[(2S,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-10-[[oxo-[4-(trifluoromethyl)anilino]methyl]amino]-3,4-dihydro-2H-1,5-benzoxazocin-2-yl]methyl]-1-methyl-3-phenylureaHomo sapiens (human)Potency63.095710
LSM-28526Homo sapiens (human)Potency19.952610
LSM-19696Homo sapiens (human)Potency15.848910
a 1062Homo sapiens (human)Potency0.631010
sepiapterinHomo sapiens (human)Potency15.848910
folic acidHomo sapiens (human)Potency25.118910
5-amino-2-phenyl-3H-triazolo[4,5-d]pyrimidin-7-oneHomo sapiens (human)Potency25.118910
2-[(3-bromo-2-imidazo[1,2-a]pyrimidinyl)methylthio]-6-methyl-1H-pyrimidin-4-oneHomo sapiens (human)Potency39.810710
N-tert-butyl-3-(3-tert-butyl-1-methyl-7-oxo-4H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxybenzenesulfonamideHomo sapiens (human)Potency89.125110
salicylaldehyde thiosemicarbazoneHomo sapiens (human)Potency31.622810
2-[5-(3-chlorophenyl)-2-furanyl]-1H-quinazolin-4-oneHomo sapiens (human)Potency25.118910
5,5-diethyl-2-(2-hydroxyethylamino)-1,6-dihydrobenzo[h]quinazolin-4-oneHomo sapiens (human)Potency25.118910
5,5-diethyl-2-hydrazinyl-1,6-dihydrobenzo[h]quinazolin-4-oneHomo sapiens (human)Potency25.118910