A Rho-associated protein kinase 2 that is encoded in the genome of rat. [OMA:Q62868, PRO:DNx]
EC 2.7.11.1;
Rho-associated, coiled-coil-containing protein kinase 2;
Rho-associated, coiled-coil-containing protein kinase II;
ROCK-II;
RhoA-binding kinase 2;
p150 ROK-alpha;
ROKalpha;
p164 ROCK-2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| aspirin | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 2 |
| fasudil | Rattus norvegicus (Norway rat) | IC50 | 1.9000 | 1 | 1 |
| indomethacin | Rattus norvegicus (Norway rat) | IC50 | 7.7000 | 1 | 2 |
| y 27632 | Rattus norvegicus (Norway rat) | IC50 | 0.8000 | 1 | 1 |
| h 89 | Rattus norvegicus (Norway rat) | IC50 | 0.2700 | 1 | 1 |
| as 1517499 | Rattus norvegicus (Norway rat) | IC50 | 0.0210 | 1 | 1 |