Page last updated: 2024-08-07 19:28:00
Cytochrome P450 2D3
A protein that is a translation product of the Cyp2d3 gene in rat. [PRO:DNx, UniProtKB:P12938]
Synonyms
EC 1.14.14.1;
CYPIID3;
Cytochrome P450-DB3;
Debrisoquine 4-hydroxylase
Research
Bioassay Publications (1)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Compounds (8)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| debrisoquin | Rattus norvegicus (Norway rat) | IC50 | 1,754.0000 | 1 | 1 |
| nortriptyline | Rattus norvegicus (Norway rat) | IC50 | 14.2000 | 1 | 1 |
| phenformin | Rattus norvegicus (Norway rat) | IC50 | 1,927.0000 | 1 | 1 |
| dexpropranolol | Rattus norvegicus (Norway rat) | IC50 | 155.0000 | 1 | 1 |
| quinidine | Rattus norvegicus (Norway rat) | IC50 | 26.9000 | 1 | 1 |
| quinine | Rattus norvegicus (Norway rat) | IC50 | 12.0000 | 1 | 1 |
| codeine | Rattus norvegicus (Norway rat) | IC50 | 4,089.0000 | 1 | 1 |
| dextromethorphan | Rattus norvegicus (Norway rat) | IC50 | 18.6000 | 1 | 1 |