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7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Sensitivity and Specificity

7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide has been researched along with Sensitivity and Specificity in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's10 (58.82)29.6817
2010's1 (5.88)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Motwani, HV1
Feng, F; Wang, H; Wang, X; Yuan, H1
Le, XC; Lu, M; Song, Y; Wang, H; Wang, X; Wang, Z; Yin, R1
Anna, L; Georgiadis, P; Kaila, S; Knudsen, LE; Kovács, K; Kyrtopoulos, SA; Makedonopoulou, P; Poirier, MC; Schoket, B1
Albert, PS; Dawsey, SM; Divi, RL; Dong, ZW; Kleiner, DE; Olivero, OA; Poirier, MC; Qiao, YL; Roth, MJ; Schrager, JA; Taylor, PR; van Gijssel, HE; Wang, GQ1
Carmella, SG; Chen, M; Hecht, SS; Jerina, DM; Yagi, H1
Akpan, V; Bacci, C; Boddi, V; Dolara, P; Fonnesu, ML; Guglielmi, F; Lodovici, M; Luceri, C1
Iyer, PC; Jerina, DM; Sayer, JM; Yagi, H1
Denissenko, M; Venkatachalam, S; Wani, AA1
Amin, S; Geacintov, NE; Hsu, TM; Liu, TM; Santella, RM1
Dasari, RR; London, SJ; Ozbal, CC; Skipper, PL; Tannenbaum, SR; Yu, MC1
Booth, E; Carnelley, T; Le, XC; Lee, J; Watson, WP; Weinfeld, M; Xing, JZ1
Dasari, RR; Gurjuar, R; Lafleur, A; Luo, W; Ozbal, C; Taghizadeh, K; Thilly, WG; Zarbl, H1
Alexandrov, K; Bartsch, H; Hillebrand, M; Kriek, E; Rojas, M; van Schooten, FJ1
Airoldi, L; Cappelli, R; Cerri, A; Fanelli, R; Fumagalli, F; Guanci, M; La Vecchia, C; Mezzetti, M; Negri, E; Panigalli, T; Pastorelli, R1
Barker, S; Carnelley, TJ; Le, XC; Tan, WG; Wang, H; Weinfeld, M1
Keohavong, P; Thilly, WG1

Trials

1 trial(s) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Sensitivity and Specificity

ArticleYear
Impact of inherited polymorphisms in glutathione S-transferase M1, microsomal epoxide hydrolase, cytochrome P450 enzymes on DNA, and blood protein adducts of benzo(a)pyrene-diolepoxide.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:8

    Topics: Aged; Base Sequence; Benzopyrenes; Biomarkers, Tumor; Blood Proteins; Cytochrome P-450 Enzyme System; DNA, Neoplasm; Epoxide Hydrolases; Genotype; Glutathione Transferase; Humans; Lung Neoplasms; Male; Microsomes, Liver; Middle Aged; Molecular Sequence Data; Polymerase Chain Reaction; Polymorphism, Genetic; Sensitivity and Specificity

1998

Other Studies

16 other study(ies) available for 7,8-dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide and Sensitivity and Specificity

ArticleYear
DNA as an in vitro trapping agent for detection of bulky genotoxic metabolites.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Sep-01, Volume: 1152

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Chromatography, Liquid; DNA; DNA Adducts; Linear Models; Mass Spectrometry; Microsomes, Liver; Models, Chemical; Mutagens; Rats; Reproducibility of Results; Sensitivity and Specificity

2020
Ultra-performance liquid chromatography-tandem mass spectrometry for rapid and highly sensitive analysis of stereoisomers of benzo[a]pyrene diol epoxide-DNA adducts.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Jul-15, Volume: 877, Issue:22

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Cell Line, Tumor; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA Adducts; Humans; Mutagens; Sensitivity and Specificity; Stereoisomerism; Tandem Mass Spectrometry

2009
Quantum dots enhanced ultrasensitive detection of DNA adducts.
    Analytical chemistry, 2009, Dec-15, Volume: 81, Issue:24

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; DNA Adducts; Electrophoresis, Capillary; Fluorescence; Humans; Immunoassay; Quantum Dots; Sensitivity and Specificity

2009
Development and validation of a direct sandwich chemiluminescence immunoassay for measuring DNA adducts of benzo[a]pyrene and other polycyclic aromatic hydrocarbons.
    Mutagenesis, 2012, Volume: 27, Issue:5

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Animals; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Female; Hep G2 Cells; Humans; Infant, Newborn; Leukocytes, Mononuclear; Luminescent Measurements; Male; MCF-7 Cells; Mice; Polycyclic Aromatic Hydrocarbons; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Staining and Labeling

2012
Semiquantitation of polycyclic aromatic hydrocarbon-DNA adducts in human esophagus by immunohistochemistry and the automated cellular imaging system.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:12

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Automation; Carcinoma, Squamous Cell; China; Culture Media; Culture Techniques; Diagnostic Imaging; DNA Adducts; Esophageal Neoplasms; Esophagectomy; Humans; Immunohistochemistry; Keratinocytes; Polycyclic Aromatic Hydrocarbons; Rabbits; Reference Values; Reproducibility of Results; Sampling Studies; Sensitivity and Specificity

2002
r-1,t-2,3,c-4-Tetrahydroxy-1,2,3,4-tetrahydrophenanthrene in human urine: a potential biomarker for assessing polycyclic aromatic hydrocarbon metabolic activation.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2003, Volume: 12, Issue:12

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Biomarkers; Biotransformation; Carcinogens, Environmental; Gas Chromatography-Mass Spectrometry; Humans; Polycyclic Aromatic Hydrocarbons; Probability; Psoriasis; Sensitivity and Specificity; Smoking; Urinalysis

2003
Benzo(a)pyrene diolepoxide (BPDE)-DNA adduct levels in leukocytes of smokers in relation to polymorphism of CYP1A1, GSTM1, GSTP1, GSTT1, and mEH.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2004, Volume: 13, Issue:8

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adolescent; Adult; Analysis of Variance; Cohort Studies; Cytochrome P-450 CYP1A1; DNA Adducts; Female; Genetic Markers; Glutathione Transferase; Humans; Leukocytes; Male; Middle Aged; Polymorphism, Genetic; Risk Assessment; Sensitivity and Specificity; Smoking; Statistics, Nonparametric

2004
3'-H-phosphonate synthesis of chiral benzo[a]pyrene diol epoxide adducts at N(2) of deoxyguanosine in oligonucleotides.
    Chemical research in toxicology, 2007, Volume: 20, Issue:2

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Chromatography, High Pressure Liquid; Deoxyguanosine; Magnetic Resonance Spectroscopy; Molecular Conformation; Oligonucleotides; Organophosphonates; Sensitivity and Specificity; Stereoisomerism; Time Factors

2007
DNA repair in human cells: quantitative assessment of bulky anti-BPDE-DNA adducts by non-competitive immunoassays.
    Carcinogenesis, 1995, Volume: 16, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adsorption; Antibodies; Carcinogens; Cells, Cultured; DNA; DNA Adducts; DNA Damage; DNA Repair; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Humans; Kinetics; Reference Standards; Sensitivity and Specificity

1995
Determination of stereospecificity of benzo[a]pyrene diolepoxide-DNA antisera with site-specifically modified oligonucleotides.
    Carcinogenesis, 1995, Volume: 16, Issue:9

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Binding Sites; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Humans; Immune Sera; Molecular Sequence Data; Oligonucleotides; Sensitivity and Specificity; Stereoisomerism

1995
Quantification of (7S,8R)-dihydroxy-(9R,10S)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene adducts in human serum albumin by laser-induced fluorescence: implications for the in vivo metabolism of benzo[a]pyrene.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:7

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Benzo(a)pyrene; Case-Control Studies; Chromatography, High Pressure Liquid; DNA Adducts; Fluorescence; Humans; Male; Middle Aged; Sensitivity and Specificity; Serum Albumin

2000
Assay for DNA damage using immunochemical recognition and capillary electrophoresis.
    Methods in molecular biology (Clifton, N.J.), 2001, Volume: 162

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adenocarcinoma; Animals; Antibodies, Monoclonal; Bromodeoxyuridine; DNA Adducts; DNA Damage; DNA, Neoplasm; Electrophoresis, Capillary; Immunochemistry; Immunoglobulin G; Lung Neoplasms; Mice; Microscopy, Fluorescence; Plasmids; Sensitivity and Specificity; Skin; Tumor Cells, Cultured

2001
Quantitative detection of benzo[alpha]pyrene diolepoxide-DNA adducts by cryogenic laser induced fluorescence.
    Chemical research in toxicology, 2003, Volume: 16, Issue:1

    Topics: Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; DNA; DNA Adducts; Freezing; Humans; Lasers; Sensitivity and Specificity; Spectrometry, Fluorescence; Tumor Cells, Cultured

2003
Validation of a new fluorometric assay for benzo[a]pyrene diolepoxide-DNA adducts in human white blood cells: comparisons with 32P-postlabeling and ELISA.
    Carcinogenesis, 1994, Volume: 15, Issue:3

    Topics: Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Enzyme-Linked Immunosorbent Assay; Fluorescence; Humans; Leukocytes; Lung Neoplasms; Phosphorus Radioisotopes; Sensitivity and Specificity

1994
Synthesis, characterization, and applications of a fluorescent probe of DNA damage.
    Chemical research in toxicology, 2001, Volume: 14, Issue:11

    Topics: Antibodies; Benzopyrenes; DNA Damage; Electrophoresis; Fluorescent Dyes; Humans; Immunoassay; Lung Neoplasms; Oligonucleotides; Sensitivity and Specificity; Tumor Cells, Cultured

2001
Determination of point mutational spectra of benzo[a]pyrene-diol epoxide in human cells.
    Environmental health perspectives, 1992, Volume: 98

    Topics: Benzopyrenes; Cells, Cultured; DNA Mutational Analysis; Electrophoresis, Agar Gel; Humans; Mutation; Polymerase Chain Reaction; Sensitivity and Specificity

1992