benserazide has been researched along with Sensitivity and Specificity in 3 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)
Excerpt | Relevance | Reference |
---|---|---|
"Ropinirole is a nonergoline dopamine D(2)-receptor agonist and has been proven to be effective in both monotherapy and combination therapy for idiopathic Parkinson's disease." | 2.73 | The effect of Madopar on the pharmacokinetics of ropinirole in healthy Chinese volunteers. ( Bi, LL; Chen, XY; Jia, YY; Luo, XX; Wen, AD; Zhong, DF, 2007) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Palmisano, C | 1 |
Brandt, G | 1 |
Pozzi, NG | 1 |
Leporini, A | 1 |
Maltese, V | 1 |
Canessa, A | 1 |
Volkmann, J | 1 |
Pezzoli, G | 1 |
Frigo, CA | 1 |
Isaias, IU | 1 |
Marques, KL | 1 |
Santos, JL | 1 |
Lopes, JA | 1 |
Lima, JL | 1 |
Wen, AD | 1 |
Jia, YY | 1 |
Luo, XX | 1 |
Bi, LL | 1 |
Chen, XY | 1 |
Zhong, DF | 1 |
1 trial available for benserazide and Sensitivity and Specificity
Article | Year |
---|---|
The effect of Madopar on the pharmacokinetics of ropinirole in healthy Chinese volunteers.
Topics: Adult; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Asian People; Benserazide | 2007 |
2 other studies available for benserazide and Sensitivity and Specificity
Article | Year |
---|---|
Sit-to-walk performance in Parkinson's disease: A comparison between faller and non-faller patients.
Topics: Accidental Falls; Aged; Aged, 80 and over; Benserazide; Case-Control Studies; Drug Combinations; Fem | 2019 |
Simultaneous chemiluminometric determination of levodopa and benserazide in a multi-pumping flow system with multivariate calibration.
Topics: Antiparkinson Agents; Automation; Benserazide; Calibration; Flow Injection Analysis; Levodopa; Lumin | 2008 |