Page last updated: 2024-10-23

benserazide and Sensitivity and Specificity

benserazide has been researched along with Sensitivity and Specificity in 3 studies

Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"Ropinirole is a nonergoline dopamine D(2)-receptor agonist and has been proven to be effective in both monotherapy and combination therapy for idiopathic Parkinson's disease."2.73The effect of Madopar on the pharmacokinetics of ropinirole in healthy Chinese volunteers. ( Bi, LL; Chen, XY; Jia, YY; Luo, XX; Wen, AD; Zhong, DF, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Palmisano, C1
Brandt, G1
Pozzi, NG1
Leporini, A1
Maltese, V1
Canessa, A1
Volkmann, J1
Pezzoli, G1
Frigo, CA1
Isaias, IU1
Marques, KL1
Santos, JL1
Lopes, JA1
Lima, JL1
Wen, AD1
Jia, YY1
Luo, XX1
Bi, LL1
Chen, XY1
Zhong, DF1

Trials

1 trial available for benserazide and Sensitivity and Specificity

ArticleYear
The effect of Madopar on the pharmacokinetics of ropinirole in healthy Chinese volunteers.
    Journal of pharmaceutical and biomedical analysis, 2007, Jan-17, Volume: 43, Issue:2

    Topics: Adult; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Asian People; Benserazide

2007

Other Studies

2 other studies available for benserazide and Sensitivity and Specificity

ArticleYear
Sit-to-walk performance in Parkinson's disease: A comparison between faller and non-faller patients.
    Clinical biomechanics (Bristol, Avon), 2019, Volume: 63

    Topics: Accidental Falls; Aged; Aged, 80 and over; Benserazide; Case-Control Studies; Drug Combinations; Fem

2019
Simultaneous chemiluminometric determination of levodopa and benserazide in a multi-pumping flow system with multivariate calibration.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2008, Volume: 24, Issue:8

    Topics: Antiparkinson Agents; Automation; Benserazide; Calibration; Flow Injection Analysis; Levodopa; Lumin

2008