Compounds > 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid
Page last updated: 2024-12-07

3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid: structure given in first source; RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID91658
CHEBI ID39308
SCHEMBL ID192771
MeSH IDM0189929

Synonyms (53)

Synonym
BB 0261358
1r-cis-permethrinic acid
3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid
CHEBI:39308 ,
3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
55701-05-8
3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid
einecs 259-768-2
cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-
STK809740
AKOS000267381
3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylic acid
permethric acid
A830761
3-[2,2-bis(chloranyl)ethenyl]-2,2-dimethyl-cyclopropane-1-carboxylic acid
3-(2,2-dichloroethenyl)-2,2-dimethyl-1-cyclopropanecarboxylic acid
FT-0640331
AKOS016039119
SCHEMBL192771
2,2-dimethyl-3-(2',2'-dichlorovinyl)-cyclopropanecarboxylic acid
2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropane-1-carboxylic acid
2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylic acid
3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropanecarboxylic acid
2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropane-carboxylic acid
3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid
2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylic acid
3-(2,2-dichloro-vinyl)-2,2-dimethylcyclopropane-1-carboxylic acid
2,2-dimethyl-3-(2',2'-dichlorovinyl)-cyclopropane-carboxylic acid
3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid
2-(2',2'-dichlorovinyl)-3,3-dimethylcyclopropane-1-carboxylic acid
2,2-dimethyl-3-(2,2-dichlorovinyl) cyclopropane carboxylic acid
LLMLSUSAKZVFOA-UHFFFAOYSA-N
2-(2,2-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylic acid
2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropane-1-carboxylic acid
2,2-dimethyl-3-(2',2'-dichlorovinyl) cyclopropanecarboxylic acid
2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropane carboxylic acid
3-(2,2-dichlorovinyl)-2,2-dimethyl-1-cyclopropanecarboxylic acid
DTXSID5028039
cis-dl-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid
mfcd00137937
permethrinic acid 10 microg/ml in methanol
beta-cyfluthrin tp2
FT-0700671
3-(2,2-dichlorovinyl)-2,2-dimethyl-(1-cyclopropane)carboxylicacid
CS-0206089
3-(2,2-dichloroethyenyl)-2,2-dimethylcyclopropanecarboxylic acid
Q27119806
3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylicacid
FT-0701335
trans-permethrinic acid 100 microg/ml in acetonitrile
SB47946
permethrinic acid 100 microg/ml in acetonitrile
LS-03917

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Following oral dosing approx."( The metabolism of cypermethrin in man: differences in urinary metabolite profiles following oral and dermal administration.
Laird, WJ; Lesser, JE; Marsh, JR; Woollen, BH, 1992)		0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
organochlorine compoundAn organochlorine compound is a compound containing at least one carbon-chlorine bond.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (16)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (18.75)18.2507
2000's5 (31.25)29.6817
2010's8 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.80

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.80 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.74 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.80)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (5.88%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other16 (94.12%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
glycine
[no description available]		2.7230alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
cypermethrin
cypermethrin : A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.. zeta-cypermethrin : A diastereoisomeric mixture comprising the isomeric pair (1R)-cis-(alphaS)- and (1S)-trans-(alphaR)-cypermethrin together with the isomeric pair (1S)-cis-(alphaS)- and (1S)-trans-(alphaS)-cypermethrin where the ratio between the isomeric pairs lies in the range 45:55 to 55:45.		2.4220aromatic ether;
cyclopropanecarboxylate ester;
nitrile;
organochlorine compound		agrochemical;
molluscicide;
pyrethroid ester acaricide;
pyrethroid ester insecticide
phencyclidine
Phencyclidine: A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.. phencyclidine : A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.		1.9910benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
fluorobenzenes
Fluorobenzenes: Derivatives of BENZENE that contain FLUORINE.. monofluorobenzene : The simplest member of the class of monofluorobenzenes that is benzene carrying a single fluoro substituent.. fluorobenzenes : Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group.		2.110monofluorobenzenesNMR chemical shift reference compound
3-phenoxybenzoic acid
3-phenoxybenzoic acid: metabolite associated with exposure to pyrethroid insecticides. 3-phenoxybenzoic acid : A phenoxybenzoic acid in which the phenoxy group is meta to the carboxy group. It is a metabolite of pyrethroid insecticides.		4.5990phenoxybenzoic acidhuman xenobiotic metabolite;
marine xenobiotic metabolite
fluorine
Fluorine: A nonmetallic, diatomic gas that is a trace element and member of the halogen family. It is used in dentistry as fluoride (FLUORIDES) to prevent dental caries.		1.9710diatomic fluorine;
gas molecular entity		NMR chemical shift reference compound
permethrin
hemoglobin Atlanta-Coventry: Leu replaced by Pro at beta75 and Leu deleted at beta141		4.6761cyclopropanecarboxylate ester;
cyclopropanes		agrochemical;
ectoparasiticide;
pyrethroid ester acaricide;
pyrethroid ester insecticide;
scabicide
3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid
3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane-1-carboxylic acid: urinary metabolite of insectiside, deltamethrin		2.110
transfluthrin
transfluthrin: an insecticide. transfluthrin : A carboxylic ester obtained by formal condensation of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and 2,3,5,6-tetrafluorobenzyl alcohol.		2.110carboxylic ester;
cyclopropanes;
organochlorine compound;
organofluorine compound		pyrethroid ester insecticide
pyrethrins
[no description available]		6.48161
ConditionIndicatedRelationship StrengthStudiesTrials
Child Behavior Disorders
Disturbances considered to be pathological based on age and stage appropriateness, e.g., conduct disturbances and anaclitic depression. This concept does not include psychoneuroses, psychoses, or personality disorders with fixed patterns.		02.1510
Delayed Effects, Prenatal Exposure
[description not available]		02.1510
Pregnancy
The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.		02.5120
Mange, Sarcoptic
[description not available]		03.4111
Scabies
A contagious cutaneous inflammation caused by the bite of the mite SARCOPTES SCABIEI. It is characterized by pruritic papular eruptions and burrows and affects primarily the axillae, elbows, wrists, and genitalia, although it can spread to cover the entire body.		03.4111
Sensitivity and Specificity
Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)		02.0310
Neuroblastoma
A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)		01.9710