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phenacetin and Sensitivity and Specificity

phenacetin has been researched along with Sensitivity and Specificity in 8 studies

Saridon: contains phenacetin, caffeine, propyphenazone & pyrithyldione

Sensitivity and Specificity: Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed)

Research Excerpts

ExcerptRelevanceReference
"Overall 20 patients with liver cirrhosis (Child-Pugh score ≥ 7, aged 48-79 years), 30 healthy young volunteers (aged 18-40 years), and 20 healthy elderly volunteers (aged 61-80 years) were enrolled."2.75Evaluating human liver reserve function by measuring serum concentrations of phenacetin and its metabolites. ( Ji, BN; Jin, H; Jin, JC; Li, SJ; Xiong, WJ; Yu, C, 2010)
" The developed assay was applied to a pharmacokinetic study in rats."1.38Highly sensitive LC-MS/MS-ESI method for simultaneous quantitation of albendazole and ricobendazole in rat plasma and its application to a rat pharmacokinetic study. ( Giri, S; Kandaswamy, M; Meena, AK; Mithra, C; Mullangi, R; Rajagopal, S; Sharma, K, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, H1
Sun, J1
Sui, X1
Liu, J1
Yan, Z1
Liu, X1
Sun, Y1
He, Z1
Liu, LY1
Han, YL1
Zhu, JH1
Yu, Q1
Yang, QJ1
Lu, J1
Guo, C1
Zhang, S1
Song, N1
Li, Q1
Fan, H1
Liu, C1
Zhang, Q1
Hu, J1
Sheng, L1
Li, Y1
Xiong, WJ1
Jin, H1
Li, SJ1
Jin, JC1
Ji, BN1
Yu, C1
Sharma, K1
Kandaswamy, M1
Mithra, C1
Meena, AK1
Giri, S1
Rajagopal, S1
Mullangi, R1
Himmelsbach, M1
Haunschmidt, M1
Buchberger, W1
Klampfl, CW1
Toraño, JS1
Verbon, A1
Guchelaar, HJ1

Trials

1 trial available for phenacetin and Sensitivity and Specificity

ArticleYear
Evaluating human liver reserve function by measuring serum concentrations of phenacetin and its metabolites.
    Journal of digestive diseases, 2010, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Chromatography, L

2010

Other Studies

7 other studies available for phenacetin and Sensitivity and Specificity

ArticleYear
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metab

2009
A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates.
    Biomedical chromatography : BMC, 2015, Volume: 29, Issue:3

    Topics: Bupropion; Calibration; Chromatography, Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450

2015
Liquid chromatography/tandem mass spectrometry method for simultaneous evaluation of activities of five cytochrome P450s using a five-drug cocktail and application to cytochrome P450 phenotyping studies in rats.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Aug-01, Volume: 871, Issue:1

    Topics: Animals; Chromatography, Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450

2008
Simultaneous quantification of capsaicin and dihydrocapsaicin in rat plasma using HPLC coupled with tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Aug-15, Volume: 878, Issue:24

    Topics: Animals; Capsaicin; Chromatography, High Pressure Liquid; Drug Stability; Least-Squares Analysis; Ph

2010
Highly sensitive LC-MS/MS-ESI method for simultaneous quantitation of albendazole and ricobendazole in rat plasma and its application to a rat pharmacokinetic study.
    Biomedical chromatography : BMC, 2012, Volume: 26, Issue:2

    Topics: Albendazole; Animals; Chromatography, Liquid; Drug Stability; Linear Models; Male; Phenacetin; Rats;

2012
Microemulsion electrokinetic chromatography with on-line atmospheric pressure photoionization mass spectrometric detection.
    Analytical chemistry, 2007, Feb-15, Volume: 79, Issue:4

    Topics: Atmospheric Pressure; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Emulsions; M

2007
Quantitative determination of thalidomide in human serum with high-performance liquid chromatography using protein precipitation with trichloroacetic acid and ultraviolet detection.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Nov-12, Volume: 734, Issue:2

    Topics: Blood Proteins; Chemical Precipitation; Chromatography, High Pressure Liquid; Drug Stability; Humans

1999