Proteins > Amine oxidase [flavin-containing] B
Page last updated: 2024-08-07 13:38:34
Amine oxidase [flavin-containing] B
An amine oxidase [flavin-containing] B that is encoded in the genome of mouse. [OMA:Q8BW75, PRO:DNx]
Synonyms
EC 1.4.3.4;
Monoamine oxidase type B;
MAO-B
Research
Bioassay Publications (8)
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
Compounds (12)
Drugs with Inhibition Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| isatin | Mus musculus (house mouse) | Ki | 6.1250 | 1 | 4 |
| heliamine | Mus musculus (house mouse) | IC50 | 1,000.0000 | 1 | 1 |
| toloxatone | Mus musculus (house mouse) | IC50 | 3.9200 | 1 | 1 |
| farnesol | Mus musculus (house mouse) | Ki | 430.0714 | 1 | 7 |
| piperine | Mus musculus (house mouse) | Ki | 3.1900 | 1 | 1 |
| aurapten | Mus musculus (house mouse) | IC50 | 0.3000 | 2 | 2 |
| rasagiline | Mus musculus (house mouse) | Ki | 0.5000 | 1 | 1 |
| formononetin | Mus musculus (house mouse) | IC50 | 11.0000 | 1 | 1 |
| lacinartin | Mus musculus (house mouse) | IC50 | 28.6000 | 1 | 1 |
| 8-(3-chlorostyryl)caffeine | Mus musculus (house mouse) | Ki | 0.1000 | 1 | 1 |
Drugs with Other Measurements
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|
| selegiline | Mus musculus (house mouse) | Activity | 0.0009 | 2 | 6 |
| desmethylselegiline | Mus musculus (house mouse) | Activity | 0.0011 | 2 | 3 |
Potent selective monoamine oxidase B inhibition by maackiain, a pterocarpan from the roots of Sophora flavescens.Bioorganic & medicinal chemistry letters, , 10-01, Volume: 26, Issue:19, 2016
A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease.Bioorganic & medicinal chemistry, , May-01, Volume: 21, Issue:9, 2013